Search Results
Results 301 - 350 of 843
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D'Incà R - - 1999
BACKGROUND: Physical exercise may exacerbate the disturbed homeostasis of Crohn's disease patients. AIM: To examine the effect of moderate physical exercise on gastrointestinal function in a group of Crohn's disease patients in remission. PATIENTS AND METHODS: The effect of one-hour's exercise at a maximum of 60% oxygen consumption was evaluated ...
Castiello U U Department of Psychology, University of Melbourne, Parkville, Victoria, Australia. - - 1999
This study assessed the adaptive response of the reach-to-grasp movement of 12 Parkinson's disease (PD) and 12 control subjects to a simultaneous perturbation of target object location and size. The main aim was to test further the reported dysfunction of PD subjects in the simultaneous activation of movement components. Participants ...
Stein R A - - 1999
This review focuses on innovative directions and recent studies in cardiovascular exercise science. Studies that address the enhancement of the diagnostic and prognostic value of exercise testing, by virtue of electrocardiographic analysis and the integration of exercise tolerance and clinical findings, are reviewed. The roles of exercise electrocardiographic testing in ...
Uppal R S - - 1999
Suction drains can be used as alternatives to conventional underwater seal drains following cardiac surgery, and may be advantageous under some circumstances. The authors present a case where a suction drain eroded into the right ventricle causing near-fatal haemorrhage following coronary artery surgery. Caution should be exercised in taking the ...
Zakhari S - - 1999
Moderate alcohol consumption (1-2 drinks a day) can be beneficial in reducing the risk of coronary artery disease. This article focuses on cellular and molecular mechanisms underlying the beneficial effect of moderate drinking, including increased plasma high-density lipoprotein levels, changes in cellular signaling, reduction in platelet function, stimulation of fibrinolysis, ...
Michaelides A P - - 1999
BACKGROUND: Exercise electrocardiography is an perfect test for the detection of coronary artery disease. We attempted to improve the diagnostic accuracy of exercise testing as a noninvasive method for the detection of coronary artery disease by using a combination of the left and right precordial leads. METHODS: We studied 245 ...
Gabriel H H - - 1999
Cardiovascular disease is the principal cause of death in Europe, the United States, and much of Asia. If sedentary people begin exercising on a regular basis, there is epidemiologal evidence of approximately 50% reduction in their risk of developing coronary heart disease. This article is an overview about epidemiology and ...
Dimov T - - 1999
The aim of our study was to evaluate the prognostic value of an early predischarge and late symptom-limited exercise tests as opposed to the evidence from the coronary angiographic examination. Twenty patients with an uncomplicated myocardial infarction were studied with an early predischarge exercise test (14-21 days) and a following ...
McCartney N - - 1999
Resistance training is widely used in fitness programs for healthy individuals of all ages and has become accepted as part of the exercise rehabilitation process for patients with coronary artery disease. It is only during the past decade that the acute circulatory responses to resistance exercise have been investigated directly, ...
Adamczewska AM - - 1998
The terrestrial red crab Gecarcoidea natalis undertakes an annual breeding migration and must sustain locomotion for prolonged periods. The migrating crabs must travel a specific distance in a fixed time and can either walk at a constant speed or walk faster for short periods and then pause to feed or ...
Fletcher G F - - 1998
Cardiac rehabilitation is an important management strategy in patients with coronary artery disease. Substantial data from both mortality and morbidity studies support the benefits. Recent studies of patients with coronary artery disease have shown that exercise confers greater benefit in those who are also on a fat-controlled diet than in ...
Duncker D J - - 1998
A pivotal role for adenosine in the regulation of coronary blood flow is still controversial. Consequently, we investigated its role in the regulation of coronary vasomotor tone in swine at rest and during graded treadmill exercise. During exercise, myocardial O2 consumption increased from 167 +/- 18 micromol/min at rest to ...
Franklin B A - - 1998
Exercise is vital if you've had a heart attack, balloon angioplasty, or bypass surgery, or if you are affected by heart disease in some other way, like having chest pain when you exert yourself. Of course, you also need to eat smart and take other healthy steps to reduce your ...
Kirk J D - - 1998
STUDY OBJECTIVES: To determine the safety and utility of immediate exercise testing in the evaluation of low-risk patients presenting to the emergency department with chest pain and its applicability to a heterogeneous population of men and women. METHODS: We conducted a prospective study of the safety and utility of immediate ...
Lamers K J - - 1998
There is an evident need for a quantitative laboratory marker for ascertaining disease activity and treatment effects in multiple sclerosis (MS) patients. Activity of the disease process in MS is accompanied by myelin breakdown and appearance of myelin basic protein (MBP) in cerebrospinal fluid (CSF). In this paper MBP in ...
Quebbemann B B - - 1998
This study was performed to determine whether nitroglycerin can increase blood flow to collateral-dependent myocardium during exercise. Intermittent repetitive occlusions of the left circumflex coronary artery (LCX) were used to stimulate growth of coronary collateral vessels in seven adult mongrel dogs. Coronary pressure distal to the occluder was measured with ...
Säfström K - - 1998
BACKGROUND: The diagnostic information from an ECG taken while at rest and an exercise test is considered less reliable in women than in men, mostly due to a high percentage of false-positive tests. This can be explained by a lower pre-test likelihood of coronary heart disease. AIMS: To evaluate the ...
Klainman E - - 1998
Twenty-nine patients with documented coronary artery disease underwent cardiopulmonary exercise tests before and following a percutaneous transluminal coronary angioplasty (PTCA). The patients medication regimen and exercise protocols remained the same in both cases. Following PTCA, significant improvement (p < 0.001-0.0001) was noted in oxygen consumption (1,526.8 +/- 470.0 vs. 1,686.2 ...
Luotolahti Matti - - 1998
The purpose of this study was to test whether the systolic myocardial wall motion abnormalities at the early stages of ischemia are applicable to the diagnosis of coronary artery disease. Forty-four patients with suspected coronary artery disease were studied with the use of low-level exercise echocardiography. Exercise was stopped at ...
Shiran A - - 1998
In this prospective study, we examined the diagnostic accuracy of exercise-induced left QRS axis deviation as a marker of LAD coronary artery stenosis. The mean frontal QRS axis of 66 consecutive patients with chest pain and exercise-induced ST segment depression referred for diagnostic coronary angiography was analyzed and related to ...
Jørgensen B - - 1998
AIMS: To study the impact of smoking on the change in exercise capacity in patients treated with coronary angioplasty. METHODS: Three hundred and sixty-eight men below 70 years of age eligible for percutaneous transluminal coronary angioplasty without previous coronary interventions were consecutively enrolled. Of the 334 patients (90.8%) who completed ...
Kaufmann P A - - 1998
BACKGROUND: It has been shown that exercise-induced coronary vasodilation of angiographically normal coronary vessels is reduced in hypercholesterolemic patients. The purpose of this study was to evaluate the effect of calcium channel blockers on coronary vasomotion of angiographically smooth coronary arteries in hypercholesterolemic patients. METHODS AND RESULTS: A total of ...
Watanabe T - - 1998
Exercise-induced myocardial ischemia is difficult to detect with ST-T changes in patients with right bundle branch block (RBBB). We sought to predict exercise-induced myocardial ischemia with QT interval behavior during exercise in patients with RBBB. Twenty-two patients with angiographically proven coronary artery disease and RBBB and 9 healthy volunteers underwent ...
Roger V L - - 1998
Exercise echocardiography has experienced a rapid rise in clinical acceptance because of its recognized ability to detect coronary artery disease in addition to attractive features such as portability, versatility and relatively low cost. To achieve and maintain accuracy and diagnostic yield, adequate training of the sonographer and the cardiologist is ...
Laughlin M H - - 1998
Aerobic exercise training induces an increase in coronary blood flow capacity that is associated with altered control of coronary vascular resistance and, therefore, coronary blood flow. The relative importance of metabolic, myogenic, endothelium-mediated, and neurohumoral control systems varies throughout the coronary arterial tree, and these control systems contribute in parallel ...
Ishibashi Y - - 1998
We previously reported that combined blockade of adenosine receptors and ATP-sensitive K+ channels (K+(ATP) channels) blunted but did not abolish the response of coronary blood flow to exercise. This study tested the hypothesis that the residual increase in coronary flow in response to exercise after adenosine receptor and K+(ATP) channel ...
Koike A - - 1998
PURPOSE: Although nitrates are known to improve indices of exercise capacity in patients with coronary artery disease, their effects on oxygen uptake kinetics during the onset of exercise have not been clarified. We evaluated the acute effects of isosorbide dinitrate on the kinetics of oxygen uptake during the onset of ...
Kaufmann P - - 1998
BACKGROUND: Clinical symptoms have been found to correlate only poorly with the severity of the culprit lesion in coronary artery disease. The purpose of the present study was to evaluate the influence of the culprit lesion and its change during exercise on clinical symptoms in patients with this condition. METHODS: ...
Miller T D - - 1998
Physical exercise has become universally accepted as an important component in the primary prevention of coronary disease and in the management of subjects with established coronary artery disease. Exercise should be utilized appropriately for each individual's needs and done in concert with aggressive modification of other risk factors such as ...
Sofair A F - - 1998
As we learn more about the origins of coronary artery disease, research has begun to focus on its prevention. The purpose of this study was to determine if exercise stress testing of the offspring of our cardiac rehabilitation patients would be a useful adjunct to their general cardiac risk factor ...
Massin M - - 1998
Children who underwent arterial switch operation for simple transposition of the great arteries in the neonatal period are now reaching an age when exercise testing becomes feasible. This study was conducted to assess exercise tolerance and electrocardiographic response to exercise stress in 50 asymptomatic children, aged 4 to 9 years, ...
Pesola G R - - 1997
BACKGROUND: Activated clotting time (ACT) values during percutaneous transluminal coronary angioplasty (PTCA) after the initial 10,000 U heparin bolus are often below target values of 350 or 400 s (Hemochron) and have to be supplemented with additional heparin. This study evaluated the initial 10 min post-heparin bolus clotting time value ...
Cox M H - - 1997
Exercise is effective in both preventing and treating coronary artery disease (CAD). Exercise improves cardiovascular efficiency and, in combination with other measures such as medication use, diet changes, and smoking cessation, may arrest or reverse atherosclerosis. Exercise prescriptions will vary according to disease level or risk, but the basic principle ...
Leung D Y - - 1997
Mitral valve prolapse is sometimes associated with chest pain, but this symptom may also be caused by coexisting coronary disease. The accuracy of exercise echocardiography in diagnosing coronary disease in these patients and the most cost-efficient diagnostic approach are unclear. We studied 96 patients (aged 59 +/- 12 years; 70 ...
Abraham P - - 1997
Atherosclerosis and inflammatory arterial diseases are rare in young people. Since the early 1980s, an increasing incidence of iliac arterial stenosis in competition cyclists has been reported. Histological findings in these individuals are specific, with fibrosis of the intimal wall on histology and no atherosclerotic or inflammatory lesions. Clinical consequences ...
Lee M - - 1997
To assess the peripheral vascular effects of estrogen in women without coronary disease, normal postmenopausal women (mean age 56 +/- 8 years) participated in a randomized, crossover trial using treadmill exercise echocardiography, and received oral conjugated estrogen, 0.625 mg/day or underwent a drug-free period. There was no significant effect on ...
Osborn L A - - 1997
We report on a case of significant exertional symptoms secondary to occlusion of a nondominant right coronary artery proximal to the sino-atrial branch, with associated exercise-induced sinus node dysfunction. Successful angioplasty of the occluded right coronary artery restored a normal functional capacity and sinus tachycardia response to exercise.
Leon A S - - 1997
PURPOSE: To examine the long-term association of leisure time physical activity (LTPA) and risk of death from coronary heart disease (CHD) and all-causes. METHODS: Data are from a prospective study of 12,138 middle-aged men at high risk for CHD participating in the MRFIT. Men were classified into deciles based on ...
Lowensteyn I - - 1997
PURPOSE: The American College of Sports Medicine recently published new guidelines to classify individuals at increased risk for coronary heart disease (CHD) before starting a vigorous (> 60% maximum oxygen consumption) exercise program. We compared the prognostic value of the new guidelines to the earlier guidelines. METHODS: Subjects included men ...
Ferri C - - 1997
The endothelium-derived peptide endothelin-1 (ET-1) was evaluated in 14 male patients [mean age 52.74 years (SEM 1.10)] affected by coronary artery disease during a bicycle electrocardiographic stress test and dipyridamole echocardiogram. Both tests were performed before and after coronary revascularization. Fourteen healthy male subjects served as controls [mean age 53.21 ...
Zhao G - - 1997
The effects of exercise training on the coronary vasodilation following activation of the Bezold-Jarisch reflex were examined in conscious dogs. Mongrel dogs were chronically instrumented using sterile techniques for measurements of systemic hemodynamics and left circumflex coronary blood flow (CBF). With the heart rate controlled (150 bpm), veratrine (0.5 to ...
Caplice N M - - 1997
OBJECTIVES: This study sought to 1) assess in vivo release of platelet-derived growth factor (PDGF) and basic fibroblast growth factor (bFGF) into the coronary circulation after vascular injury in human subjects; and 2) evaluate mitogenic effects of PDGF and bFGF on the patient's own vascular smooth muscle cells (VSMCs). BACKGROUND: ...
Fowler G C - - 1997
Exercise testing is an effective method for evaluating patients with chest pain, for diagnosing and managing coronary artery disease, for determining prognosis in patients with known coronary disease, for determining exercise capacity, for evaluating exercise-induced arrhythmias, for verifying the safety of exercise, and for customizing an exercise prescription. With proper ...
Munt B - - 1997
Exercise-induced left bundle branch block is a relatively rare finding during exercise tolerance testing. A 36-year-old female with intermittent exercise-induced left bundle branch block, a MIBI study suggesting anterior ischemia and normal coronary arteries is reported. A review of the English and French language literature published from January 1985 to ...
Schell W D - - 1997
In recent years, it has been established in humans that progression of atherosclerosis can be slowed, and in some cases, regressed. This differs from previous decades in which such observations were only considered possible in animals. The emergence of more effective lipid-lowering agents along with aggressive dietary and other lifestyle ...
Yamada H - - 1997
Multivariable analysis of clinical and exercise test variables has the potential to become both a useful tool for assisting in the diagnosis of coronary artery disease and reducing the cost of evaluating patients with suspected coronary disease. Managed care and capitation require that tests such as the exercise test or ...
Pepi M - - 1997
In hypertension, several factors disturb coronary circulation and the metabolic reserve of the heart. This study was undertaken to test whether in hypertensive patients global and regional left ventricular (LV) function is related during exercise to the presence of significant coronary stenosis and whether lowering of coronary perfusion pressure through ...
Vassalli G - - 1997
BACKGROUND: Coronary flow reserve (CFR) is reduced in a majority of patients after heart transplantation (HTx). Pharmacological interventions, however, provide only limited information on CFR under physiological conditions. Thus, CFR during exercise was evaluated in the present study. METHODS AND RESULTS: Coronary angiography was performed at rest and during supine ...
Ishibashi Y - - 1997
Previously, we observed that alpha 1-but not alpha 2-adrenergic vasoconstriction restricted blood flow distal to a coronary artery stenosis that resulted in myocardial hypoperfusion during exercise. This study was performed to test the hypothesis that vascular smooth muscle alpha 2-adrenergic vasoconstriction during exercise does exert a flow-limiting effect distal to ...
Papazoglou N - - 1997
The purpose of this study was to delineate among the usually gathered parameters in an electrocardiographic exercise test the determinants of its positive outcome (delta ST decreases > or = 1 mm measured at 80 msec from the J point). The authors studied 832 patients investigated with Bruce's exercise testing ...
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