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Nikolaidis Michalis G - - 2013
Despite the progress of analytic techniques and the refinement of study designs, striking disagreement exists among studies regarding the influence of exercise on muscle function and redox homeostasis in the elderly. The repeated eccentric exercise model was applied to produce long-lasting and extensive changes in redox biomarkers and to reveal ...
Venojärvi Mika - - 2013
Our aim was to determine whether 12 weekś aerobic Nordic walking (NW) or resistance exercise training (RT) without diet-induced weight loss could decrease oxidative stress and atherogenic index of plasma (AIP), prevalence of metabolic syndrome (MetS) and MetS score in middle-aged men with impaired glucose regulation (IGR) (n =144. 54.5 ...
Haus Jacob M - - 2013
Hepatic steatosis, insulin resistance, inflammation, low levels of polyunsaturated lipids, and adiponectin are implicated in the development and progression of nonalcoholic fatty liver disease (NAFLD). We examined the effects of short-term aerobic exercise on these metabolic risk factors. Obese individuals (N = 17, 34.3 ± 1.0 kg/m²) with clinically confirmed ...
Zhonghui Zhao Z Zhejiang Police College, Hangzhou, Zhejiang 310053, PR - - 2014
The present study was designed to determine the effects of Ganoderma lucidum polysaccharides (GL-PS) on exhaustive exercise-induced oxidative stress in skeletal muscle tissues of mice. The mice were divided into four groups (three GL-PS administered groups and the control group). The control group was administered with distilled water and GL-PS ...
Braakhuis Andrea J - - 2013
Abstract Exercise-induced oxidative stress is implicated in muscle damage and fatigue which has led athletes to embark on antioxidant supplementation regimes to negate these effects. This study investigated the intake of vitamin C (VC) (1 g), blackcurrant (BC) juice (15 mg VC, 300 mg anthocyanins) and placebo in isocaloric drink ...
Ramos Dionizio - - 2013
Both acute exercise and excessive training can cause oxidative stress. The resulting increase in free radicals and the inadequate response from antioxidant systems can lead to a framework of cellular damage. An association between affected tissue and the biomarkers of oxidative stress that appear in plasma has not been clearly ...
Lo Presti R - - 2013
Physical exercise influences the body's oxidative status. The modifications can involve lipids, proteins and nucleic acids, and different effects seem to be induced by regular and acute exercise respectively. We examined protein oxidation, expressed as concentration of protein carbonyl groups (PC), in trained subjects before (time 0), 10 min (time ...
Yu Feng - - 2013
Chronic administration of D-galactose simulates the changes in natural senescence and accelerates aging in animal models and has been used in aging research. The present study was undertaken to investigate the molecular mechanisms underlying the effects of exercise on learning and memory in rats with D-galactose-induced aging. The learning and ...
Drigny J - - 2013
BACKGROUND: QT dispersion (QTd) is a marker of myocardial electrical instability, and is increased in metabolic syndrome (MetS). Moderate intensity continuous exercise (MICE) training was shown to improve QTd in MetS patients. OBJECTIVES: To describe long-term effects of MICE and high-intensity interval exercise training (HIIT) on QTd parameters in MetS. ...
Lamprecht Manfred - - 2013
Obesity and sedentary lifestyle are associated with increased oxidative stress, inflammation and vessel dysfunction. Previous research has shown that an encapsulated fruit/berry/vegetable juice powder (FBV) supplement or controlled exercise training improve the markers of redox biology, low-grade inflammation and circulation. The aim of the present study was to assess the ...
Layec Gwenael - - 2013
AIM: Short-term exercise training may induce metabolic and performance adaptations before any changes in mitochondrial enzyme potential. However, there has not been a study that has directly assessed changes in mitochondrial oxidative capacity or metabolic control as a consequence of such training in vivo. Therefore, we used (31) P-magnetic resonance ...
Hamakawa Michiru - - 2013
Long-term exercise prior to brain ischemia enhances the activities of antioxidant enzymes and leads to a significant reduction in brain damage and neurological deficits in rats subjected to transient middle cerebral artery occlusion. However, it has not been established whether relatively short-term exercise generates similar results following middle cerebral artery ...
Silva Luciano A - - 2013
Abstract Thirty-six male rats were used; divided into 6 groups (n = 6): saline; creatine (Cr); eccentric exercise (EE) plus saline 24 h (saline + 24 h); eccentric exercise plus Cr 24 h (Cr + 24 h); eccentric exercise plus saline 48 h (saline + 48 h); and eccentric exercise plus Cr 48 h (Cr + 48h). Cr supplementation was administered as a solution of 300 mg · ...
Shen Yuh-Chiang - - 2013
Background and Purpose: Caffeic acid phenethyl ester (CAPE), a phenolic compound isolated from propolis, displays a variety of biological activities. The aim is to examine the protective effect and mechanisms of CAPE on an eccentric exercise-induced muscle injury model. Experimental Approach: An intermittent downhill eccentric exercise protocol was used. The ...
Reuland Danielle J - - 2013
Oxidative stress is a component of many human diseases, including cardiovascular diseases (CVD). Exercise and various phytochemicals activate nuclear factor (erythroid-derived 2)-like 2 (Nrf2), the "master regulator" of antioxidant defenses, and attenuate CVD. This review highlights Nrf2 regulation by exercise and phytochemicals, and the role of Nrf2 as a therapeutic ...
Chen Zichao - - 2013
The main purpose of this study was to examine the effect of Radix Pseudostellariae polysaccharides (RPPs) against swimming exercise-induced oxidative stress in male rats. A total of 40 male Wistar rats were randomized into four groups: the control (C), low-dose RPP supplementation (LRS), medium-dose RPP supplementation (MRS) and high-dose RPP ...
Quindry John - - 2013
Previous research findings indicate that environmental temperature can influence exercise-induced oxidative-stress responses, although the response to variable temperatures is unknown. The purpose of this study was to investigate the effect of warm, cold, and "neutral," or room, environmental temperatures on the blood oxidative stress associated with exercise and recovery. Participants ...
Mashhadi Nafiseh Shokri - - 2013
Ginger (rich in gingerols and shogaols) rhizomes have been widely used as dietary spices and to treat different diseases in Asia. Cinnamon (containing cinnamic aldehyde and cinnamyl aldehyde) is used as spices and as a pharmacological agent in ancient medicine. Intense exercise can result in oxidative damage to cellular compounds ...
Darvishi Leila - - 2013
Quercetin is a health-enhancing antioxidant bioflavonoid (1-3). This flavonoid occurs in variety of natural fruits and vegetables such as apple, cranberry, onion, broccoli, and teas. Many studies have shown that quercetin has possible positive effects on exercise performance. The aim of this study is the evaluation of effects of quercetin ...
Kim Hyun-Sub HS Department of Social Sports, College of Natural Science, Dae Jeon University, Daejeon, - - 2013
Hypertension is designated as either essential (primary) hypertension or secondary hypertension and is defined as a consistently elevated blood pressure exceeding 140/90 mmHg. Hypertension is called "the silent killer" because it often causes no symptoms for many years, even decades, until it finally damages certain critical organs. In various causes ...
Awobajo F O FO Department of Physiology, Faculty of Basic Medical Sciences, University of Lagos. - - 2013
Exercise is a physical activity that maintains physical fitness and optimum health of an individual. The objective of this study was to determine changes in redox-oxidative status, lipid profile, cortisol, testosterone and fasting blood glucose (FBG) in trained and untrained male subjects during a programmed exercise session. Twenty (20) trained ...
Silva Luiz Fernando Almeida - - 2013
Traumatic brain injury (TBI) is a major cause of acquired epilepsy and significant resources are required to develop a better understanding of the pathologic mechanism as targets for potential therapies. Thus, we decided to investigate whether physical exercise after fluid percussion injury (FPI) protects from oxidative and neurochemical alterations as ...
Astorino Todd A - - 2013
INTRODUCTION: The primary aim of the current study was to determine the effect of two doses of chronic high intensity interval training (HIT) on changes in maximal fat oxidation (MFO) and body composition. METHODS: Sedentary women (N = 23, age and VO2max = 24.2 ± 6.2 yr and 30.3 ± ...
Isacco Laurie - - 2013
PURPOSE: Abdominal and lower body fat mass tissues exhibit particular metabolic profiles at rest and during exercise. However data are missing in normal weight women during exercise. The purpose of this study was to investigate the impact of low (LA/LB) and high (HA/LB) abdominal to lower body (A/LB) fat mass ...
Solomon Thomas P J - - 2013
OBJECTIVE: To determine the influence of dietary glycemic index on exercise training-induced adaptations in substrate oxidation in obesity. DESIGN AND METHODS: Twenty older, obese individuals undertook 3-months of fully-supervised aerobic exercise and were randomised to low (LoGIX) or high glycemic (HiGIX) diets. Changes in indirect calorimetry (VO2 ; VCO2 ) ...
Hu Xiaofei - - 2013
To screen target proteins of oxidative stress which mediate the effects of exercise on preventing nonalcoholic fatty liver disease (NAFLD), the methods for selecting carbonylated proteins were modified, and carbonylated proteins were profiled. The results showed that treadmill training reduced oxidative stress and the levels of intrahepatic triglyceride (IHTG). The ...
Camiletti-Moirón D - - 2013
The aim of the present systematic review was to investigate the influence of different exercise programs on brain oxidative stress. A search of the literature was conducted up to 1 December 2012 across five databases: PUBMED, SCOPUS, SPORTS DISCUS, Web of Science, and The Cochrane Library. The search strategy used ...
Reis L F F - - 2013
Background: Support and treatment options have been widely discussed in recent decades with the aim of improving morbidity, mortality and quality of life of chronic respiratory disease (COPD) patients. Although it is believed that longer pulmonary rehabilitation programs can provide better results, most of the evidence comes from short-term programs. ...
McAnulty Lisa S - - 2013
Resveratrol and quercetin function as antioxidants and anti-inflammatories in vitro, but these mechanisms have been minimally examined in combination in exercising humans. The purpose of this investigation was to examine supplementation as a countermeasure against oxidative stress and inflammation in response to exercise. Fourteen athletes were randomly assigned, in a ...
Concepcion-Huertas Melquiades - - 2013
Abstract The present research was designed to evaluate the adaptive responses to oxidative stress and inflammation in handball players subjected to well-controlled training intervals over one-year of competition. Seven blood samples were collected over the season of the study, approximately one a month. Plasma lipid peroxidation, nitrite, cytokines (IL-1β, IL-6, ...
Gravier Gilles - - 2013
We hypothesized that the changes in blood oxidant/antioxidant status during incremental maximal cycling exercise could affect the motor drive to leg muscles. Indeed, the oxygen free radicals activate the metabosensitive muscle afferents which are suspected to elicit an adaptive motor response delaying fatigue. Fifteen healthy subjects performed an incremental cycling ...
Fogarty Mark C - - 2013
Introduction: Although pharmacological antioxidants have previously been investigated for a prophylactic effect against exercise oxidative stress, is not known if α-lipoic acid supplementation can protect against DNA damage following high intensity isolated quadriceps exercise. This randomised controlled investigation was designed to test the hypothesis that fourteen days of α-lipoic acid ...
Wadley Glenn D - - 2013
The aim of this research was to examine the impact of the xanthine oxidase (XO) inhibitor allopurinol on the skeletal muscle activation of cell signaling kinases' and adaptations to mitochondrial proteins and antioxidant enzymes following acute endurance exercise and endurance-training. Male Sprague Dawley rats performed either acute exercise (60 min ...
Sparks Lauren M LM Translational Research Institute for Metabolism and Diabetes, Orlando, FL 32804, USA. - - 2013
Type 2 diabetes (T2D) has features of disordered lipid and glucose metabolism, due in part to reduced mitochondrial content. Our objective was to investigate effects of different types of exercise on mitochondrial content and substrate oxidation in individuals with T2D (ancillary study of the randomized controlled trial Health Benefits of ...
Reamy Brian V - - 2013
Cardiovascular disease remains the leading cause of death in the United States despite a 50% decrease in deaths from myocardial infarction and stroke in the past 30 years associated with improvements in blood pressure and lipid control. The National Health and Nutrition Evaluation Survey found that the least prevalent metrics ...
Davis Brittany B Department of Vascular Surgery, Yale School of Medicine, New Haven, Connecticut ; Veterans Administration Health Care System, West Haven, - - 2013
Although research unanimously maintains that exercise can ward off cardiovascular disease (CVD), the optimal type, duration, intensity, and combination of forms are yet not clear. In our review of existing rodent-based studies on exercise and cardiovascular health, we attempt to find the optimal forms, intensities, and durations of exercise. Using ...
Hodgson Adrian B AB Human Performance Laboratory, School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, - - 2013
Green tea is made from the leaves of the Camellia sinensis L plant, which is rich in polyphenol catechins and caffeine. There is increasing interest in the potential role of green tea extract (GTE) in fat metabolism and its influence on health and exercise performance. A number of studies have ...
Braakhuis Andrea J - - 2013
The beneficial effects of exercise and a healthy diet are well documented in the general population, but poorly understood in elite athletes. Previous research in sub-elite athletes suggest regular training and an antioxidant-rich diet enhances antioxidant defences, but not performance. PURPOSE: To investigate whether habitual diet and/or exercise (training status ...
Hart Nikolett - - 2013
High capacity runner (HCR) rats have been developed by divergent artificial selection for treadmill endurance running capacity to explore an aerobic biology-disease connection. The beneficial effects of resveratrol supplementation have been demonstrated in endurance running and the antioxidant capacity of resveratrol is also demonstrated. In this study we examine whether ...
Radák Zsolt - - 2013
The effects of treadmill running (8 weeks, 5 times/ week, 1hour/day at 27 m/min), caloric restriction, and cocoa supplementation on brain function and oxidative stress markers were tested. The Morris maze test was used to appraise rat memory. Regular exercise significantly improved spatial learning performance. The level of oxidative stress ...
Bhutani Surabhi - - 2013
Objective: This study examined whether the combination of Alternate day fasting (ADF) plus exercise produces superior changes in body composition and plasma lipid levels when compared to each intervention alone. Designs and Methods: Obese subjects (n = 64) were randomized to 1 of 4 groups for 12 weeks: 1) combination ...
Chang Rei-Yeuh - - 2013
Abstract Objectives: A single bout of t'ai chi (TC) exercise was previously found to be associated with a significant increase in post-exercise adiponectin levels in individuals with cardiovascular risk factors. The objective of this study was to examine the long-term effects of 24-month habitual TC exercise on adiponectin levels, glucose ...
Di Blasio A - - 2013
Aim: Executive functions are susceptible to age-related changes, and menopause has also been shown to be linked with their decline. The aim of the present study was to investigate the variables related to executive functions in postmenopausal women not involved in controlled dietary and physical exercise programs and without hormone-replacement ...
Chan Huan Hao - - 2013
This study examined the acute effect of sprint interval exercise (SIE) on postexercise oxygen consumption, substrate oxidation, and blood pressure. The participants were 10 healthy males aged 21-27 years. Following overnight fasts, each participant undertook 2 trials in a random balanced order: (i) four 30-s bouts of SIE on a ...
Gayda Mathieu - - 2013
Skeletal muscle substrate oxidation was compared during moderate-intensity continuous exercise (MICE) and high-intensity intermittent exercise (HIIE) in patients with heart failure and reduced ejection fraction (HFREF). Eighteen patients (aged 60 ± 9 years; LVEF, 26 ± 7%) randomly performed MICE (22 minutes at 60% of peak power) and HIIE (30 ...
Teixeira V H - - 2013
Aim: This study aimed to investigate the response of blood antioxidants and biomarkers of lipid peroxidation, muscle damage and inflammation to a 1000m kayak trial in elite male kayakers. Methods: Enzymatic (superoxide dismutase [SOD], glutathione reductase [Gr] and glutathione peroxidase [GPx] activities) and non-enzymatic (total antioxidant status [TAS], uric acid, ...
Sanchis-Gomar Fabian - - 2013
Oxidative stress results from damage to tissues caused by free radicals and is increased by exercise. Peroxiredoxins (PRXs) maintain the cellular reducing environment by scavenging intracellular hydrogen peroxide. It has been recently noted that physical exercise has a positive effect on the PRX system, exerting a protective effect against oxidative ...
Jeppesen Jacob - - 2013
Lipid metabolism is important for health and insulin action, yet the fundamental process of regulating lipid metabolism during muscle contraction is incompletely understood. Here, we show that LKB1 muscle-specific knockout (LKB1 MKO) mice display decreased fatty acid (FA) oxidation during treadmill exercise. LKB1 MKO mice also show decreased muscle SIK3 ...
Frasier Chad R - - 2013
AIMS: We have previously shown that exercise leads to sustainable cardioprotection through a mechanism involving improved glutathione replenishment. This study was conducted to determine if redox-dependent modifications in glutathione reductase (GR) were involved in exercise cardioprotection. Furthermore, we sought to determine if reactive oxygen species generated by NADPH oxidase and/or ...
Sun Mengwei - - 2013
AIMS: In this study, we investigated the interaction between exercise-induced mitochondrial adaptation of large vessels and the effects of chronic anabolic androgenic steroids (AASs). METHODS AND RESULTS: Four groups of Sprague-Dawley rats were studied: (i) sedentary, (ii) sedentary + nandrolone-treated, (iii) aerobic exercise trained, and (iv) trained + nandrolone-treated. Aerobic ...
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