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Results 101 - 150 of 1165
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Gwozdzinski Krzysztof K Department of Molecular Biophysics, University of Lodz, Pomorska 141/143, 90-236 Lodz, - - 2013
The aim of this study was to investigate alterations in haemoglobin conformation and parameters related to oxidative stress in whole erythrocytes, membranes, and plasma after a single bout of exercise in a group of young untrained men. Venous blood samples from eleven healthy young untrained males (age = 22 ± ...
Moro Cedric C Inserm UMR1048, Institute of Metabolic and Cardiovascular Diseases, Obesity Research Laboratory, CHU Rangueil, 1 Avenue Jean Poulhès, BP84225, 31432, Toulouse Cedex 4, France, - - 2013
The aim of the present study was to investigate the influence of substrate availability on fuel selection during exercise. Eight endurance-trained male cyclists performed 90-min exercise at 70 % of their maximal oxygen uptake in a cross-over design, either in rested condition (CON) or the day after 2-h exercise practised at ...
Sutkowy PaweĊ‚ - - 2013
Background. The aim of this study was to determine the effect of Finnish sauna as a regeneration method post-exercise on the oxidant-antioxidant balance in healthy men. Material. 43 men aged 24.0 ± 4.3 years performed a 30-min aerobic exercise on a cycle ergometer and rested for 39 min at a ...
Lee Sang-Ho SH Research Institute of Sport Science, Kyungwoon University, Republic of - - 2013
[Purpose] This study was conducted to identify the effects of walking on the body composition, health-related physical fitness, and serum lipids as part of efforts to encourage middle-aged people to participate in walking as a regular and sustainable exercise. [Methods] This study was conducted as a pretest-posttest control group study. ...
Parker Lewan - - 2013
The aim of the current study was to examine the influence of exercise intensity on systemic oxidative stress (OS) and endogenous antioxidant capacity. Non-smoking, sedentary healthy adult males (n = 14) participated in two exercise sessions using an electronically braked cycle ergometer. The first session consisted of a graded exercise test to ...
Flaherty Joseph M - - 2013
The purpose of the study was to determine whether short-term high-intensity aerobic interval training improves resting pulmonary diffusing capacity for nitric oxide (DLNO) and carbon monoxide (DLCO). Twenty eight sedentary females [mean (SD) age 32 (11) yrs, body mass index 24.3 (5.7) kg/m2] were randomly assigned to either a self-directed ...
Barreto Mario M Pediatric Unit, Sant'Andrea Hospital, NESMOS Department, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy. Electronic address: - - 2013
The fractional concentration of exhaled nitric oxide (FENO), a known marker of atopic-eosinophilic inflammation, may be used as a surrogate to assess exercise-induced bronchoconstriction (EIB) in asthmatic children. The predictive value of baseline FENO for EIB appears to be influenced by several factors, including age, atopy, current therapy with corticosteroids ...
Krause Mauricio - - 2013
To investigate the effect of 16 weeks of aerobic training performed at two different intensities on nitric oxide (tNOx) availability and iNOS/nNOS expression, oxidative stress (OS) and inflammation in obese humans with or without type 2 diabetes mellitus (T2DM). Twenty-five sedentary, obese (BMI > 30 kg/m(2)) males (52.8 ± 7.2 years); 12 controls versus 13 T2DM were ...
Henderson Gregory C - - 2013
A single bout of exercise can alter subsequent resting metabolism for many hours and into the next day. However, differences between men and women, effects of nutritional state, and relative effects of resting metabolic rate (RMR) and respiratory exchange ratio (RER) in controlling the increase in lipid oxidation (Lox) after ...
Fiuza-Luces Carmen - - 2013
Chronic graft-versus-host disease (cGVHD) is a frequent cause of morbimortality after allogeneic hematopoietic stem cell transplantation (allo-HSCT), and severely compromises patients' physical capacity. Despite the aggressive nature of the disease, aerobic exercise training can positively impact survival as well as clinical and functional parameters. We analyzed potential mechanisms underlying the ...
Bouzid Mohamed A - - 2013
This comparative study examined the effects of regular low intensity aerobic exercise on oxidative stress markers in older adults. The study was carried out on fifteen sedentary subjects (age: 65.1 ± 3.5 years) versus eighteen subjects performing fitness exercises (age: 65.8 ± 3.3 years). Before and after an incremental exercise ...
Gray Patrick - - 2013
Due to the potential anti-inflammatory properties of fish-derived long chain n-3 fatty acids, it has been suggested that athletes should regularly consume fish oils, although evidence in support of this recommendation is not clear. While fish oils can positively modulate immune function, it remains possible that, due to their high ...
Hrncic D - - 2013
The aim of the study was to examine the effects of chronic exercise training on seizures induced by homocysteine thiolactone (HCT) in adult rats. Rats were assigned to: sedentary control; exercise control; sedentary+HCT; exercise+HCT group. Animals in the exercise groups ran 30 min daily on a treadmill for 30 consecutive days ...
Bracken Richard M - - 2013
Optimal carbohydrate ingestion strategies as nutritional therapy for glycogen storage diseases have not been fully realised, in part, due to difficulties in accessing patient cohorts, alongside limited details on metabolic effects and insight into working mechanisms. The present pilot study compared glycaemic and fuel oxidation responses following the ingestion of ...
Masschelein Evi - - 2013
Hypoxia-induced muscle wasting is a phenomenon often described with prolonged stays at high altitude, which has been attributed to altered protein metabolism. We hypothesized that acute normobaric hypoxia would induce a negative net protein balance by repressing anabolic and activating proteolytic signaling pathways at rest and postexercise and that those ...
Martorell Miquel M Laboratory of Physical Activity Sciences, University of the Balearic Islands, Crtra. Valldemossa, km 7.5, E-07122, Palma de Mallorca, Spain, and CIBER: CB12/03/30038 Fisiopatología de la Obesidad y la Nutrición, CIBERobn, Instituto de Salud Carlos III (ISCIII), - - 2014
Diet supplementation with omega-3 fatty acids could influence the oxidative equilibrium, enhancing a pro-oxidant status. The aim was to determine the effects of diet supplementation with docosahexaenoic acid (DHA), training, and acute exercise on oxidative balance in neutrophils. Fifteen volunteer male soccer players were randomly assigned to a placebo or ...
Murias Juan M - - 2013
It has been proposed that the adjustment of oxygen uptake (VO2) during the exercise on-transient is controlled intracellularly in young, healthy individuals, and that insufficient local O2 delivery plays a rate-limiting role in aging and disease only. This review shows that adequate O2 provision to the active tissues is critical ...
Li Jie J College of Physical Education, Northwest Normal University, Lanzhou, Gansu 730070, P.R. - - 2013
The effects of different modes of hypoxic exercise training on free radical production and antioxidant enzyme activity in the brain of rats were investigated in this study. A total of 40 healthy 2-month-old male Wister rats were randomly assigned to 5 groups according to different training modes. Endurance training sessions ...
Louche Katie - - 2013
Context:Skeletal muscle lipase and intramyocellular triglyceride (IMTG) play a role in obesity-related metabolic disorders.Objectives:The aim of the present study was to investigate the impact of 8 weeks of endurance exercise training on IMTG content and lipolytic proteins in obese male subjects.Design and Volunteers:Ten obese subjects completed an 8-week supervised endurance ...
Takahashi M - - 2013
The purpose of this study was to investigate the effects of curcumin supplementation on exercise-induced oxidative stress in humans. 10 male participants, ages 26.8±2.0 years (mean±SE), completed 3 trials in a random order: (1) placebo (control), (2) single (only before exercise) and (3) double (before and immediately after exercise) curcumin ...
Casuso R A - - 2013
We aimed to test exercise-induced adaptations on skeletal muscle when quercetin is supplemented. Four groups of rats were tested: quercetin sedentary, quercetin exercised, placebo sedentary, and placebo exercised. Treadmill exercise training took place 5 days a week for 6 weeks. Quercetin groups were supplemented with quercetin, via gavage, on alternate ...
Dantas de Lucas Ricardo - - 2013
Abstract The purpose of the present investigation was to identify muscle damage, inflammatory response and oxidative stress blood markers in athletes undertaking the ultra-endurance MultiSport Brazil race. Eleven well-trained male athletes (34.3 ± 3.1 years, 74.0 ± 7.6 kg; 172.2 ± 5.1 cm) participated in the study and performed the race, which consisted of about 90 km of alternating ...
Rech Anderson - - 2013
Introduction: We examined oxidative stress and skeletal muscle damage resulting from acute strength, aerobic, or concurrent exercise in rats. Methods: The animals were divided into control (C), strength (SE), aerobic (AE), and combined (CE) exercise groups. The animals were euthanized at 3 different time points (6, 24, and 48 hours) ...
Farah C - - 2013
Exercise is an efficient strategy for myocardial protection against ischemia-reperfusion (IR) injury. Although endothelial nitric oxide synthase (eNOS) is phosphorylated and activated during exercise, its role in exercise-induced cardioprotection remains unknown. This study investigated whether modulation of eNOS activation during IR could participate in the exercise-induced cardioprotection against IR injury. ...
Faes Camille C CRIS EA647, Université de Lyon 1, Villeurbanne, - - 2014
Very few studies have investigated the effects of exercise on the biological parameters involved in vaso-occlusive events in sickle cell anaemia (SCA). The aim of this study was to test how a mild-moderate endurance exercise modulates oxidative stress, nitric oxide bioavailability and endothelial activation in SCA patients and healthy individuals. ...
Ji Li Li - - 2013
ABSTRACT Contraction-induced production of reactive oxygen species (ROS) has been implicated in oxidative stress to skeletal muscle for the past few decades. As research advances more evidence has revealed a more complete role of ROS under both physiological and pathological conditions. The current review postulated that moderate intensity of physical ...
Markworth James F - - 2013
Classical pro-inflammatory, and more recently discovered lipid mediators with pro-resolving bioactivity, exert a complex role in the initiation, control, and resolution of inflammation. We investigated lipid mediator responses to resistance exercise and treatment with the non-steroidal anti-inflammatory drug (NSAID) ibuprofen. Human subjects undertook a single bout of resistance exercise (80% ...
Karabulut Aysun Bay - - 2013
This experimental study aimed to determine the effects of the combined application of regular exercises and massage on the values of Malondialdehyde (MDA), Nitric Oxide (NOx), Glutathione (GSH), Adenosine Deaminase (ADA) and Superoxide Dismutase (SOD). Twenty five sedentary women (32-50 years) who did not have the habit of getting regularly ...
Goes André T R - - 2013
Parkinson's disease (PD) is characterized by progressive dopamine (DA) depletion in the striatum. Exercise has been shown to be a promising non-pharmacological approach to reduce the risk of neurodegeneration diseases. This study was designed to investigate the potential neuroprotective effect of swimming training (ST) in a mouse model of PD ...
Viña Jose - - 2013
Scientific evidence links physical activity to several benefits. Recently, we proposed the idea that exercise can be regarded as a drug. As with many drugs, dosage is of great importance. However, to issue a public recommendation of physical activity in aging is not an easy task. Exercise in the elderly ...
Schwarz Neil A - - 2013
Capsaicin and evodiamine are 2 thermogenic agents recognized for their ability to stimulate the sympathetic nervous system. We hypothesized that both capsaicin and evodiamine would be effective at increasing thermogenesis and lipid oxidation during rest and exercise. In a randomized, cross-over design, 11 men ingested 500 mg of cayenne pepper ...
Yan Feng - - 2013
Abstract Context. Cordyceps sinensis (Berk.) Sacc. (Clavicipitaceae) is a famous medicinal fungus (mushroom) in Chinese herbal medicine. Polysaccharides from Cordyceps sinensis (CSP) have been identified as active ingredients responsible for its biological activities. Although many pharmacological actions of CSP have received a great deal of attention, research in this area ...
Ceusters Justine D - - 2013
Horses are outstanding athletes, performing in many different disciplines involving different kinds of efforts and metabolic responses. Depending on exercise intensity, their skeletal muscle oxygenation decreases, and the reperfusion at cessation of the exercise can cause excessive production of free radicals. This study on cultured primary equine myoblasts investigated the ...
Redmond Jessica G - - 2013
To determine if a small body size at birth is associated with an unfavorable metabolic profile and a reduced response to exercise training in young adults. Thirty-six college students, all singletons born to term, participated. Subjects were defined as either high ponderal index (HIGHPI) or low ponderal index (LOWPI). LOWPI ...
Mitranun W - - 2013
To determine the effects of continuous aerobic exercise training (CON) vs interval aerobic exercise training (INT) on glycemic control and endothelium-dependent vasodilatation, 43 participants with type 2 diabetes were randomly allocated to the sedentary, CON, and INT groups. The CON and INT exercise training programs were designed to yield the ...
Lee SoJung S Division of Weight Management and Wellness - - 2013
It is unclear whether regular exercise alone (no caloric restriction) is a useful strategy to reduce adiposity and obesity-related metabolic risk factors in obese girls. We examined the effects of aerobic (AE) vs. resistance exercise (RE) alone on visceral adipose tissue (VAT), intrahepatic lipid, and insulin sensitivity in obese girls. ...
Schwindling S - - 2013
The intensity that elicits maximal fat oxidation (Fatmax) is recommended for training fat metabolism. However, it remains unclear whether Fatmax leads to the highest fat oxidation rates during prolonged exercise. It was hypothesized that there are no differences in fat oxidation rates among 3 different exercise intensities. Therefore, fat metabolism ...
Martin Daniel S - - 2013
The study of healthy human volunteers ascending to high altitude provides a robust model of the complex physiological interplay that emulates human adaptation to hypoxaemia in clinical conditions. Nitric oxide (NO) metabolism may play an important role in both adaptation to high altitude and response to hypoxaemia during critical illness ...
Dieter Brad P - - 2013
The dicarbonyl methylglyoxal (MGO) is an endogenous metabolite and a known intracellular precursor of advanced glycation endproducts (AGEs). High serum levels of MGO have been correlated with MGO-derived AGEs in individuals with type 2 diabetes (T2DM). Furthermore, there is human and animal evidence to suggest that MGO is causal in ...
Jacobs Kevin A - - 2013
Context/objective: To describe and compare substrate oxidation and partitioning during voluntary arm ergometry in individuals with paraplegia and non-disabled individuals over a wide range of exercise intensities. Cross-sectional study. Clinical research facility. Ten apparently healthy, sedentary men with paraplegia and seven healthy, non-disabled subjects. Rest and continuous progressive voluntary arm ...
Li Yong-Qiang - - 2013
To investigate the prevalence and distribution of metabolic syndrome (MetS) and the impact of exercise, smoking, and educational level on the risk of MetS in a southern Chinese population. A cross-sectional study was conducted in Zhuhai City, China from June to August 2012. Data on exercise, smoking, and educational level, ...
Ko Il Gyu - - 2013
An overactive bladder (OAB) may be defined as urgency that is a sudden, compelling, difficult to defer desire to pass urine that is usually accompanied by frequency and nocturia and possibly by incontinence. Obesity and old age are two factors in various causes of OAB. Several epidemiologic studies have identified ...
Baraas Faisal F Department of Cardiology, Medical Faculty, National Cardiovascular Center Harapan Kita Hospital, University of Indonesia, Jakarta, - - 2013
Moderate-to-high intensity of exercise training within 2 to 3 months decreases oxygen free radicals (reactive oxygen species, ROS) and increases nitric oxide (NO) in outpatients with myocardial infarction. There is no data about the association of ROS and NO after short-term low-intensity exercise training within 5 days in patients hospitalized ...
Araneda O F - - 2013
It is a well-established fact that exercise increases pro-oxidants and favors oxidative stress; however, this phenomenon has been poorly studied in human lungs. Pro-oxidative generation (H2O2, NO2 (-)), lipid peroxidation markers (MDA), and inflammation (pH) in exhaled breath condensate (EBC) have been determined through data from 10 active subjects who ...
Wright David C DC Department of Human Health and Nutritional Sciences, University of Guelph, Guelph ON N1G 2W1, - - 2014
Owing to its obligatory role in locomotion and the fact that it accounts for the vast majority of whole-body glucose and lipid oxidation, much work has focused on studying the biochemical adaptations that occur in skeletal muscle in response to exercise. However, over the past several years there has been ...
Campos Juliane C - - 2013
Reactive oxygen and nitrogen species regulate a wide array of signaling pathways that governs cardiovascular physiology. However, oxidant stress resulting from disrupted redox signaling has an adverse impact on the pathogenesis and progression of cardiovascular diseases. In this review, we address how redox signaling and oxidant stress affect the pathophysiology ...
Sarga Linda - - 2013
Regular exercise promotes brain function via a wide range of adaptive responses, including the increased expression of antioxidant and oxidative DNA damage-repairing systems. Accumulation of oxidized DNA base lesions and strand breaks is etiologically linked to for example aging processes and age-associated diseases. Here we tested whether exercise training has ...
Fittipaldi Simona - - 2013
Abstract The multiple roles that have been associated with heat shock proteins (HSPs), inside and outside cells are remarkable. HSPs have been found to play a fundamental role in multiple stress conditions and to offer protection from subsequent insults. Exercise, because of the physiological stresses associated with it, is one ...
Finkler Maya - - 2013
Abstract Physical exercise has many benefits, but it might also have a negative impact on the body, depending on the training level, length of workout, gender, age and fitness. The negative effects of physical exercise are commonly attributed to an imbalance between the levels of antioxidants (both low molecular weight ...
Rengo Giuseppe - - 2013
Aging is a well-recognized risk factor for several different forms of cardiovascular disease. However, mechanisms by which aging exerts its negative effect on outcome have been only partially clarified. Numerous evidence indicate that aging is associated with alterations of several mechanisms whose integrity confers protective action on the heart and ...
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