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Broadbent Suzanne S School of Health and Human Sciences, Southern Cross University, PO Box 157, Lismore, NSW 2480, Australia. - - 2013
Chronic Fatigue Syndrome is a debilitating disorder with an unknown aetiology but suspected multifactorial origins. Common "triggers" include severe viral infections and emotional stress. Recent studies have also found evidence of immune dysfunction and elevated inflammatory cytokines in CFS patients, but there has been considerable variation in the outcome measures ...
Neme Ide Bernardo - - 2013
The purpose of this study was to observe the time course of muscle damage and inflammatory responses following an eccentric overload resistance-training (EO) program. 3 females (23.8 ± 2.6 years; 70.9 ± 12.7 kg; 1.6 ± 0.08 m) and 5 males (23.8 ± 2.6 years; 75.1 ± 11.2 kg; 1.8 ± 0.1 m) underwent ...
Huang Chi-Chang - - 2013
This study investigates whether a 12-week swimming exercise training can prevent liver damage or senescence associated biomarkers in an experimental aging model in rats. Twenty-three male Sprague-Dawley rats were divided into four groups: vehicle treatment with sedentary control (C, n = 6), aging induction with sedentary (A, n = 6), ...
Karch Izabela I Department of Cardiac and Vascular Diseases, The John Paul II Hospital, Jagiellonian University Medical College, Krakow, Poland. - - 2013
Physical activity is associated with a lower risk of cardiovascular disease but the mechanism underlying this association is unclear. These benefits of physical activity might result from its effects on inflammation and endothelial function. We investigated whether cardiorespiratory fitness and the level of physical activity are associated with biomarkers of ...
Tang Clarice Y - - 2013
The aim of the study is to explore the experiences of inpatients with an acute exacerbation of chronic obstructive pulmonary disease, who participated in a very early exercise programme while acutely unwell. This qualitative study analysed responses from participant interviews as part of a mixed method trial whereby participants were ...
Nunes Rafael Amorim Belo - - 2013
C-reactive protein (CRP) is a marker of systemic inflammatory activity and may be modulated by physical fitness. Treadmill exercise testing is used to evaluate cardiovascular health through different variables including exercise capacity, heart rate and blood pressure responses. It was hypothesized that CRP levels are associated with these variables in ...
Babbitt Dianne M - - 2013
African Americans have the highest prevalence of hypertension in the world which may emanate from their predisposition to heightened endothelial inflammation. The purpose of this study was to determine the effects of a 6-month aerobic exercise training (AEXT) intervention on the inflammatory biomarkers interleukin-10 (IL-10), interleukin-6 (IL-6), and endothelial microparticle ...
Malin Steven K - - 2013
Impaired glucose tolerant (IGT) adults are at elevated risk for cardiovascular disease (CVD). Exercise or metformin reduce CVD risk, but the efficacy of combining treatments is unclear. To determine the effects of exercise training plus metformin (EM), compared with each treatment alone, on CVD risk factors in IGT adults. Subjects ...
Williams Paul T - - 2013
Test whether inadequate exercise is related to sepsis mortality. Mortality surveillance of an epidemiological cohort of 155,484 National Walkers' and Runners' Health Study participants residing in the United States. Deaths were monitored for an average of 11.6-years using the National Death index through December 31, 2008. Cox proportional hazard analyses ...
Schier Robert - - 2013
Background. Perioperative vascular function has been widely studied using noninvasive techniques that measure reactive hyperemia as a surrogate marker of vascular function. However, studies are limited to a static setting with patients tested at rest. We hypothesized that exercise would increase reactive hyperemia as measured by digital thermal monitoring (DTM) ...
Hovanloo Fariborz - - 2013
Chronic and inflammatory diseases are major causes of mortality. Although the anti-inflammatory effects of exercise have been confirmed, but the effect of different types of exercise on inflammatory markers is different. The aim of this study is comparing the effects of two types of sprint interval (SIT) and continuous endurance ...
Kim Hye-Jeong - - 2013
Increased adiponectin is a result of an anti-arteriosclerotic effect and is related to the prevention of arteriosclerosis. However, it is uncertain whether cardiac rehabilitation and exercise (CRE) increase adiponectin in patients after acute coronary syndrome (ACS). To assess the effects of CRE intervention on adiponectin in patients after ACS. Forty ...
Sugama Kaoru - - 2013
It has been consistently shown that circulating levels of interleukin (IL)-6, IL-8, IL-1 receptor antagonist (IL-1ra) and IL-10 increase remarkably following endurance exercise longer than 2 h such as marathon and triathlon races. However, no studies have compared changes in the plasma and urinary levels of these cytokines after endurance ...
Botta Amy - - 2013
PGC-1α, a transcriptional coactivator, controls inflammation and mitochondrial gene expression in insulin-sensitive tissues following exercise intervention. However, attributing such effects to PGC-1α is counfounded by exercise-induced fluctuations in blood glucose, insulin or bodyweight in diabetic patients. The goal of this study was to investigate the role of PGC-1α on inflammation ...
Takeda Kenichi - - 2013
Upper-extremity exercise is for pulmonary rehabilitation. The 6-minute pegboard and ring test (6PBRT) was developed to evaluate arm exercise capacity in patients with chronic obstructive pulmonary disease (COPD). The purpose of this study was to characterize the 6PBRT and evaluate its relationship with upper-extremity activities of daily living (ADLs) in ...
Begue Gwénaëlle - - 2013
Cytokine interleukin-6 (IL-6) is an essential regulator of satellite cell-mediated hypertrophic muscle growth through the transcription factor signal transducer and activator of transcription 3 (STAT3). The importance of this pathway linked to the modulation of myogenic regulatory factors expression in rat skeletal muscle undergoing hypertrophy following resistance exercise, has not ...
Kanda Kazue - - 2013
The purpose of this study was to determine the relationships among delayed-onset muscle soreness (DOMS), muscle damage and inflammatory responses to eccentric exercise and investigate the underlying mechanisms. Nine healthy males performed one-leg calf-raise exercise with their right leg on a force plate. They performed 10 sets of 40 repetitions ...
Samjoo I A IA 1] Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada [2] Department of Medicine, McMaster University, Hamilton, Ontario, - - 2013
Obesity is associated with low-grade systemic inflammation, in part because of secretion of proinflammatory cytokines, resulting into peripheral insulin resistance (IR). Increased oxidative stress is proposed to link adiposity and chronic inflammation. The effects of endurance exercise in modulating these outcomes in insulin-resistant obese adults remain unclear. We investigated the ...
van de Weert-van Leeuwen Pauline Barbera - - 2013
Regular exercise is positively associated with health. It has also been suggested to exert anti-inflammatory effects. In healthy subjects, a single exercise session results in immune cell activation, which is characterized by production of immune modulatory peptides (e.g. IL-6, IL-8), a leukocytosis and enhanced immune cell functions. Upon cessation of ...
Lee Na Kyung NK Department of Rehabilitation Science, Graduate school, Daegu University, Kyeongbuk, Republic of - - 2013
The major contributors to physical disability after stroke are the negative impairments related to loss of functional ability and muscle strength. The aim of this study was to examine the effects of close kinetic chain (CKC) exercise and open kinetic chain (OKC) exercise on muscle activation of the paretic lower ...
Mangner Norman - - 2013
Inflammatory cytokines like tumor necrosis factor alpha (TNF-α) are elevated in congestive heart failure and are known to induce the production of reactive oxygen species as well as to deteriorate respiratory muscle function. Given the antioxidative effects of exercise training, the aim of the present study was to investigate if ...
Little Robert M D RM Canadian Centre for Activity and Aging, University of Western Ontario London, London, Ontario, - - 2013
Fear of injury is reported as a barrier to exercise by older adults. However, the literature is limited in describing exercise injuries in older adults. This study prospectively evaluated the 12-month incidence of exercise-related injuries to community-dwelling older adults (n=167 respondents; 63 men, 104 women; mean age 69±5 year). A ...
Lan Ching C Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital and National Taiwan University, College of Medicine, 7 Chung-Shan South Road, Taipei 100, - - 2013
Exercise training is the cornerstone of rehabilitation for patients with cardiovascular disease (CVD). Although high-intensity exercise has significant cardiovascular benefits, light-to-moderate intensity aerobic exercise also offers health benefits. With lower-intensity workouts, patients may be able to exercise for longer periods of time and increase the acceptance of exercise, particularly in ...
Bravi Andrea - - 2013
Although physiological (e.g., exercise) and pathological (e.g., infection) stress affecting the cardiovascular system have both been documented to be associated with a reduction in overall heart rate variability (HRV), it remains unclear if loss of HRV is ubiquitously similar across different domains of variability analysis or if distinct patterns of ...
Qutubuddin Abu - - 2013
Objective. The concept of forced exercise has drawn attention for the treatment of Parkinson's disease symptoms with anecdotal reports of success. This study sought to ascertain any significant effect of forced exercise using a motorized stationary bicycle when compared to controls on Parkinson's disease symptoms in a blinded, randomized, and ...
Strohacker Kelley K The Miriam Hospital and the Warren Alpert Medical School of Brown University, Providence, Rhode Island, - - 2013
Determine whether body mass index (BMI) and physical activity (PA) above, at or below MET minute per week (MMW) levels recommended in the 2008 Physical Activity Guidelines interact or have additive effects on interleukin (IL)-6, C reactive protein (CRP), fibrinogen, interleukin6 (IL-6) soluble receptor (IL-6sr), soluble E-selectin and soluble intracellular ...
Bennett Philippa - - 2013
Introduction: NICE stated exercise stress tests (EST) should not be used to diagnose obstructive coronary artery disease in patients presenting with chest pain presumed to be of cardiac origin. Methods: A retrospective review of 209 patients with presumed cardiac chest pain was done. EST results, GRACE scores and need for ...
Morris Gerwyn - - 2013
'Encephalomyelitis disseminata' (multiple sclerosis) and myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) are both classified as diseases of the central nervous system by the World Health Organization. This review aims to compare the phenomenological and neuroimmune characteristics of MS with those of ME/CFS. There are remarkable phenomenological and neuroimmune overlaps between both ...
Zgierska Aleksandra A Department of Family Medicine, University of Wisconsin-Madison, 1100 Delaplaine Ct., Madison, WI 53715, - - 2013
Background. A randomized trial suggests that meditation and exercise may prevent acute respiratory infection (ARI). This paper explores potential mediating mechanisms. Methods. Community-recruited adults were randomly assigned to three nonblinded arms: 8-week mindfulness-based stress reduction (N = 51), moderate-intensity exercise (N = 51), or wait-list control (N = 52). Primary ...
Jamshidpour Boshra B Physical Therapist, Department of Physical Therapy, Tehran University of Medical Sciences, - - 2013
Aim: Cardiac rehabilitation is a key part in the treatment of coronary artery disease (CAD) by its anti-infammatory effects. However, the effect of exercise training programs on salivary concentrations of high-sensitivity C-reactive protein (hs-CRP) in patients with coronary artery disease has not been well studied. The objective of this study ...
Mitchell Cameron J - - 2013
To determine relationships between post-exercise changes in systemic [testosterone, growth hormone (GH), insulin like grow factor 1 (IGF-1) and interleukin 6 (IL-6)], or intramuscular [skeletal muscle androgen receptor (AR) protein content and p70S6K phosphorylation status] factors in a moderately-sized cohort of young men exhibiting divergent resistance training-mediated muscle hypertrophy. Twenty ...
Wan Zhongxiao - - 2013
[This corrects the article on p. e41719 in vol. 7.].
Hackney Anthony Carl AC Department of Exercise & Sport Sciences, Applied Physiology Laboratory, AND Department of Nutrition, School of Public Health, University of North Carolina, Chapel Hill, North Carolina, USA. - - 2013
The Overtraining Syndrome (OTS) is a physically debilitating medical condition that results in athletes being totally compromised in their capacity to perform and compete. Many physiological systems are affected by the process of overtraining and the development of the OTS which results from it; but one system in particular, the ...
López-Sánchez Marta - - 2013
A subclinical left ventricle diastolic dysfunction (LVDD) has been described in patients with chronic obstructive pulmonary disease (COPD). To evaluate the prevalence of LVDD in stable severe COPD patients, to analyze its relationship with exercise capacity and to look for its possible causes (lung hyperinflation, ventricular interdependence or inflammatory mechanisms). ...
Terra R - - 2012
Physical exercise can improve health and may lead to changes in the functionality of the immune system. Moderate intensity exercise can reduce the risk of infection by shifting the overall immune response towards a T helper type 1 pattern. This study investigates the effect of 12 weeks of swimming on ...
Ho Suleen S - - 2012
Physical activity has been shown to lower levels of inflammatory markers. However, results are inconsistent, indicating different modes of exercise may have different effects on inflammatory cytokines. We aimed to investigate the effects of 12 weeks of moderate-intensity aerobic, resistance, or combination exercise on TNF-α and IL-6 compared to no exercise ...
Jones Sara B SB Yale School of Public Health, New Haven, CT 06520, - - 2013
Physical activity is associated with improved breast cancer survival, but the underlying mechanisms, possibly including modification of the inflammatory state, are not well understood. We analyzed changes in interleukin (IL)-6, C-reactive protein (CRP), and TNF-α in a randomized controlled trial of exercise in postmenopausal breast cancer survivors. Seventy-five women, recruited ...
Mancuso M M Neurological Clinic, University of Pisa, Italy. - - 2012
Fatigue and exercise intolerance are common symptoms of mitochondrial diseases, but difficult to be clinically assessed. New methods to quantify these rather common complaints are strongly needed in the clinical practice. Coenzyme Q10 administration and aerobic exercise may improve exercise intolerance, but more definite studies are still pending. Herein, we ...
Janicek J - - 2012
Fibrotic myopathy can cause incapacitating gait abnormalities. Transection of the fibrotic mass followed by early post operative exercise is the best treatment for fibrotic myopathy. A laser may be used to transect the fibrotic mass. Assessment of the effectiveness of therapies for fibrotic myopathy has been limited to subjective evaluation. ...
Broderick Gordon - - 2012
Though potentially linked to the basic physiology of stress response we still have no clear understanding of Gulf War Illness (GWI), a debilitating illness presenting with a complex constellation of immune, endocrine and neurological symptoms. Here we compared male GWI (n=20) with healthy veterans (n=22) and subjects with chronic fatigue ...
Mentz Robert J RJ Duke University Medical Center, Durham, NC, USA. - - 2013
The aim of this study was to investigate the clinical characteristics, exercise training response, β-blocker selectivity, and outcomes in patients with heart failure (HF) and chronic obstructive pulmonary disease (COPD). We performed an analysis of HF-ACTION, which randomized 2,331 patients with HF having an ejection fraction of ≤35% to usual ...
Lisman Peter - - 2012
PURPOSE: This study investigated associations between injuries and individual components of the Marine Corps Physical Fitness Test (PFT), self-reported exercise and previous injury history, and Functional Movement Screen (FMS) scores. METHODS: A cohort of 874 men enrolled in either six (n = 447) or 10 (n = 427) weeks of ...
Pereira G B - - 2012
The purpose of the present study was to examine the acute effects of resistance training (RT) on CD4+ and CD8+ T lymphocytes apoptosis (annexin V+) and migration (CX(3)CR1). Twelve subjects performed two RT sessions (3 sets of 9 exercises) with 1min (Hyper-1) and 3min (Hyper-3) of rest-interval length between sets ...
- - 2012
OBJECTIVE: Ischemic heart disease (IHD) is associated with decreased exercise tolerance and it is subjectively reported as angina pectoris or dyspnea. Inflammation and pro- inflammatory cytokines are related to progression of IHD, but their level is seldom analyzed in association with self reported exercise tolerance. METHODS: Women aged 35-75 years ...
Zembron-Lacny A - - 2012
α-Lipoic acid (αLA), as an inductor of hydrogen peroxide (H(2)O(2)) and nitrogen oxide (NO) generation and modulator of thiol redox status, plays an important role in cell signalling pathways. The study was designed to observe the effect of αLA on inflammatory response through changes in H(2)O(2) and NO levels as ...
Garcia J J - - 2012
Regular exercise is a good non-pharmacological treatment of metabolic syndrome in that it improves obesity, diabetes, and inflammation. The 72 kDa extracellular heat shock protein (eHsp72) is released during exercise, thus stimulating the inflammatory responses. The aim of the present work was to evaluate the effect of regular exercise on the ...
Donatto F F - - 2012
Cancer cachexia is a multifactorial syndrome characterised by progressive weight loss, frequently accompanied by anorexia, sarcopenia, and chronic systemic inflammation. The white adipose tissue is markedly affected by cachexia and contributes to this syndrome throught the secretion of pro-inflammatory factors which reach the adjacent tissues and the circulation. A nonpharmacologic ...
Skjerbæk Anders G - - 2012
BACKGROUND: Heat sensitivity (HS) is reported by 58% of all persons with multiple sclerosis (MS), causing symptom exacerbation possibly limiting exercise participation. OBJECTIVE: The purpose of this study was to test the hypotheses that (a) a relationship between exercise-induced changes in core-temperature (C(temp)) and changes in symptom intensity exists, and ...
Reihmane Dace - - 2012
Data on interleukin-6 (IL-6) and tumor necrosis factor-α (TNF-α) release during acute exercise are not conclusive and lack information about the impact of physical inactivity. Some studies have shown an increase, but others report no changes in IL-6 and TNF-α release during exercise. We have now studied the temporal relationship ...
Zuhl Micah - - 2012
Gastrointestinal distress, such as diarrhoea, cramping, vomiting, nausea and gastric pain are common among athletes during training and competition. The mechanisms that cause these symptoms are not fully understood. The stress of heat and oxidative damage during exercise causes disruption to intestinal epithelial cell tight junction proteins resulting in increased ...
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