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Duke Joseph W JW University of Oregon - - 2014
Adults with a history of very preterm birth (<32 weeks gestational age; PRET) have reduced lung function and significantly lower lung diffusion capacity for carbon monoxide (DLCO) relative to individuals born at term (CONT). Low DLCO may predispose PRET to diffusion limitation during exercise, particularly while breathing hypoxic gas because ...
Hajizadeh Maleki Behzad B Department of Exercise Physiology, Faculty of Physical Education and Sport Science, Urmia University, Urmia, - - 2014
To examine the effects of long-term low-to-intensive cycling training on seminal cytokines and semen parameters in male road cyclists. Repeated measures design. The Exercise Physiology Laboratory of the Urmia University. Twenty-four healthy nonprofessional male road cyclists (23.1 ± 6.2 years) participated in this study. All subjects participated in a 16-week ...
Thirapatarapong Wilawan W Department of Rehabilitation Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700 Thailand; Department of Rehabilitation and Regenerative Medicine, Columbia University Medical Center, NY, NY 10032 USA. Electronic address: - - 2014
To determine; (i) the effect of PH on exercise capacity, gas exchange and oxygen pulse; (ii) the variables that correlate with mean pulmonary artery pressure (mPAP) in severe COPD patients. We reviewed 98 severe COPD patients who had pulmonary function, right heart catheterisation, and cardiopulmonary exercise testing (CPET) performed within ...
Kim Chul-Ho CH Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota. Electronic address: - - 2014
Cardiac resynchronization therapy (CRT) has been an important treatment for heart failure. However, it is controversial as to whether an individualized approach to altering AV and VV timing intervals would improve outcomes. Changes in respiratory patterns and gas exchange are dynamic and may be influenced by timing delays. Light exercise ...
Maleki Behzad Hajizadeh BH *Faculty of Physical Education and Sport Science, Department of Exercise Physiology, Urmia University, Urmia, Iran; †Faculty of Physical Education and Sport Science, Department of Exercise Physiology, Urmia University, Urmia, Iran; and ‡Department of Morphological Sciences, School of Medicine, University of Córdoba, Córdoba, - - 2014
To examine the effects of 16 weeks of intensive cycling training on seminal reactive oxygen species (ROS), malondialdehyde (MDA), superoxide dismutase (SOD), catalase, and total antioxidant capacity (TAC) in male road cyclists. Repeated measures design. The Exercise Physiology Laboratory of the Urmia University. Twenty-four healthy nonprofessional male road cyclists (aged ...
Smolka Lukasz L University School of Physical Education in Wroclaw, Department of Physiology and Biochemistry , Wroclaw, - - 2014
The purpose of the study was to investigate the effects of implementing additional respiratory dead space during cycloergometry-based aerobic training. The primary outcome measures were respiratory exchange ratio (RER) and carbon dioxide production (VCO2). Two groups of young healthy males: Experimental (Exp, n = 15) and Control (Con, n = ...
Tan Xiaoyue X Department of Pulmonary Function Test, Shanghai Pulmonary Hospital Affiliated to Tongji University, Shanghai, China; State Key Laboratory of Cardiovascular Disease, Heart-Lung Function Testing Center, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, - - 2014
Decline in oxygen uptake efficiency (OUE), especially during exercise, is found in patients with chronic heart failure. In this study we aimed to test the validity and usefulness of OUE in evaluating gas exchange abnormality of patients with idiopathic pulmonary arterial hypertension (IPAH). We retrospectively investigated the cardiopulmonary exercise test ...
Scott Christopher B CB Exercise, Health and Sports Sciences Department, University of Southern Maine, Gorham, ME 04038, USA. - - 2014
While no doubt thought about for thousands of years, it was Antoine Lavoisier in the late 18th century who is largely credited with the first "modern" investigations of biological energy exchanges. From Lavoisier's work with combustion and respiration a scientific trend emerges that extends to the present day: the world ...
O'Donnell Denis E DE Division of Respiratory and Critical Care Medicine, Department of Medicine, Queen's University, 102 Stuart Street, Kingston, Ontario K7L 2V6, Canada. Electronic address: - - 2014
Peripheral airway dysfunction, inhomogeneous ventilation distribution, gas trapping, and impaired pulmonary gas exchange are variably present in all stages of chronic obstructive pulmonary disease (COPD). This article provides a cogent physiologic explanation for the relentless progression of activity-related dyspnea and exercise intolerance that all too commonly characterizes COPD. The spectrum ...
Broberg Craig S CS Adult Congenital Heart Disease Program, Division of Cardiovascular Medicine, Oregon Health and Science University, Portland, OR, United States. Electronic address: - - 2013
Eisenmenger physiology may contribute to abnormal pulmonary mechanics and gas exchange and thus impaired functional capacity. We explored the relationship between lung function and gas exchange parameters with exercise capacity and survival. Stable adult patients with Eisenmenger syndrome (N=32) were prospectively studied using spirometry, lung volumes, diffusion capacity, and blood ...
Scharhag-Rosenberger F - - 2013
We sought to investigate the effects of wearing a mobile respiratory gas analysis system during a treadmill test on blood lactate (bLa) concentrations and commonly applied bLa thresholds. A total of 16 recreational athletes (31±3 years, V̇O2max: 58±6 ml · min-1 · kg-1) performed one multistage treadmill test with and one without gas exchange measurements ...
McCabe Colm - - 2013
Persistent obstruction in the pulmonary artery following acute pulmonary embolism (PE) can give rise to both chronic thromboembolic pulmonary hypertension (CTEPH) and chronic thromboembolic disease without PH (CTED). We hypothesised that cardiopulmonary exercise testing (CPET) may be able to differentiate patients with CTEPH and CTED following unresolved PE which may ...
Haouzi Philippe - - 2013
Populations of III and IV muscle afferent fibers located in the adventitia of the small vessels appear to respond to the level of venular distension and to the recruitment of the vascular bed within the skeletal muscles. The central nervous system is thus informed on the level of muscle hyperemia ...
Erickson Harold P HP Departments of Cell Biology and Biochemistry; Duke University Medical Center; Durham, NC - - 2013
FNDC5 (fibronectin domain-containing [protein] 5) was initially discovered and characterized by two groups in 2002. In 2011 FNDC5 burst into prominence as the parent of irisin, a small protein containing the fibronectin type III domain. Irisin was proposed to be secreted by skeletal muscle cells in response to exercise, and ...
Paterson David J - - 2013
One hundred years ago in this Journal, Krogh and Lindhard published a seminal paper highlighting the importance of the brain in the control of breathing during exercise. This symposium report reviews the historical developments that have taken place since 1913, and attempts to place the detailed neuro-circuitry thought to underpin ...
Hajizadeh Maleki B - - 2013
The purpose of this study was to evaluate the seminal 8-Isoprostane, reactive oxygen species (ROS), malondialdehyde (MDA), superoxide dismutase (SOD), catalase, total antioxidant capacity (TAC) in subjects with different level of physical fitness. A total of 161 semen samples were obtained from three groups of healthy males, including elite athletes ...
Elbelt Ulf - - 2013
The recently identified myokine, irisin has raised great expectations as a potential target in the conservative treatment of obesity. This review focuses on studies exploring the effects of irisin in humans. Peroxisome proliferator-activated receptor γ coactivator-1 α expression in skeletal muscles is induced by exercise followed by expression of the ...
Bergstrom Haley C - - 2013
Critical power (CP) from the 3-min test was compared to the power outputs associated with thresholds determined from gas exchange parameters that have been used to demarcate the exercise-intensity domains including the respiratory compensation point (RCP), gas exchange threshold (GET), and ventilatory threshold (VT). Twenty-eight participants performed an incremental-cycle ergometer ...
Stickland Michael K - - 2013
As the first step in the oxygen-transport chain, the lung has a critical task: optimizing the exchange of respiratory gases to maintain delivery of oxygen and the elimination of carbon dioxide. In healthy subjects, gas exchange, as evaluated by the alveolar-to-arterial PO2 difference (A-aDO2), worsens with incremental exercise, and typically ...
Tattersall Glenn J - - 2013
Gas exchange in animals is ultimately diffusion based, generally occurring across dedicated respiratory organs. In many aquatic amphibians, however, multiple modes of gas exchange exist, allowing for the partitioning of O uptake and CO excretion between respiratory organs with different efficiencies. For example, due to the physical properties of O ...
Thirapatarapong Wilawan - - 2013
Impaired ventilation on cardiopulmonary exercise test (CPET) is seen in patients with chronic obstructive pulmonary disease (COPD). However, evaluation of the differences of abnormal gas exchange in COPD according to GOLD severity criteria is limited. A retrospective review was performed on all COPD patients referred for CPET at our center ...
Taylor Bryan J BJ Division of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, Rochester, MN, - - 2013
We determined whether a non-invasive gas exchange based estimate of pulmonary vascular (PV) capacitance [PVCAP = stroke volume (SV) × pulmonary arterial pressure (Ppa)] (GXCAP) tracked the PV response to exercise in heart-failure (HF) patients. Pulmonary wedge pressure (Ppw), Ppa, PV resistance (PVR), and gas exchange were measured simultaneously during ...
Marcellis Rik G J - - 2012
BACKGROUND: Cardiopulmonary exercise testing (CPET) with blood gas analysis may be helpful when there is a discrepancy between clinical findings and physiologic tests at rest. The aim of this study was to examine the added value of CPET compared to the measurement of the diffusing capacity of the lung for ...
Allen K K Langford House, Equine Hospital, University of Bristol, Langford, UK. - - 2013
The effect of palatal instability (PI) on measures of ventilation and gas exchange is not well understood. To assess to what degree different severities of naturally occurring palatal dysfunction affect ventilation and gas exchange during strenuous exercise. A retrospective study was performed using data collected from 40 Thoroughbred racehorses diagnosed ...
Courtney Sean M - - 2012
There are large interindividual differences in exercise capacity. It is well established that there is a genetic basis for these differences. However, the genetic factors underlying this variation are undefined. Therefore, the purpose of this study was to identify novel putative quantitative trait loci (QTL) for exercise capacity by measuring ...
Kato John-David - - 2012
PURPOSE:: Exercise recommendations for patients with sickle cell trait (SCT) and myocardial infarction (MI) are limited. This case report describes such a patient, who subsequently participated in cardiac rehabilitation (CR). CASE:: Patient experienced sudden intense chest pressure and shortness of breath while singing in church. Electrocardiogram and cardiac enzymes confirmed ...
Allstadt Andrew - - 2012
Certain invasive plants may rely on interference mechanisms (e.g., allelopathy) to gain competitive superiority over native species. But expending resources on interference presumably exacts a cost in another life-history trait, so that the significance of interference competition for invasion ecology remains uncertain. We model ecological invasion when combined effects of ...
Kelly Scott A SA Department of Genetics, Carolina Center for Genome Sciences, University of North Carolina, Chapel Hill, North Carolina 27599-7264, USA. - - 2012
The biological basis of voluntary exercise is complex and simultaneously controlled by peripheral (ability) and central (motivation) mechanisms. The accompanying natural reward, potential addiction, and the motivation associated with exercise are hypothesized to be regulated by multiple brain regions, neurotransmitters, peptides, and hormones. We generated a large (n = 815) ...
Carraro Attilio - - 2012
Although high anxiety is common in people with intellectual disabilities (ID) and the anxiolytic effects of exercise have been systematically recognised in clinical and non-clinical populations, research is scant concerning the role played by exercise on anxiety in people with ID. The purpose of this study was to investigate the ...
Kim Chul-Ho - - 2012
Patients with pulmonary arterial hypertension (PAH) and heart failure (HF) display many abnormalities in respiratory gas exchange. These abnormalities are accentuated with exercise and track with disease severity. However, use of gas exchange measures in day-to-day clinical practice is limited by several issues, including the large number of variables available ...
Stroescu Carmen - - 2012
Pulmonary rehabilitation is a comprehensive therapeutic intervention with proven efficacy in relieving symptoms and increasing exercise tolerance in patients with chronic respiratory diseases.One of the main components of a pulmonary rehabilitation program is lower limbs exercise training. There are several ways of establishing the optimal intensity of the exercise training, ...
Rissanen Antti-Pekka E - - 2012
The magnitude and timing of oxygenation responses in highly active leg muscle, less active arm muscle, and cerebral tissue, have not been studied with simultaneous alveolar gas exchange measurement during incremental treadmill exercise. Nor is it known, if blood O(2) carrying capacity affects the tissue-specific oxygenation responses. Thus, we investigated ...
Bulckaen Massimo - - 2011
Exercise training is beneficial for hemodialysis patients, but it should be tailored to individual abilities and willingness to participate. This study evaluated the effects of different 6-month programs of physical activity in 18 patients of a single hemodialysis unit. Before and after a 12-month control period (T0), and following 3 ...
Cingi C - - 2011
This article describes the authors' course, which takes facial plastic surgeons through specific exercises to demonstrate the esthetic impact of 3D manipulations of the nose and face. The course components are described, which include 3D assessment, exercises in manual dexterity, and improving imagination in sculpting facial and nasal features for ...
Jacobs Cale A - - 2011
Passive stretching exercise protocols, as part of outpatient treatment or home exercise programs, are used to improve hypomobility. Despite the cosmopolitan use of stretching exercises, little is known about the forces being applied to the joint during these routine treatments. Clinical review. Articles were identified using MEDLINE and Google Scholar ...
Jean-St-Michel Emilie - - 2011
: Remote ischemic preconditioning (RIPC) induced by transient limb ischemia releases a dialysable circulating protective factor that reduces ischemia-reperfusion injury. Exercise performance in highly trained athletes is limited by tissue hypoxemia and acidosis, which may therefore represent a type of ischemia-reperfusion stress modifiable by RIPC. : National-level swimmers, 13-27 yr, ...
Strobel Natalie A - - 2011
: Exercise increases the production of reactive oxygen species (ROS) in skeletal muscle, and athletes often consume antioxidant supplements in the belief they will attenuate ROS-related muscle damage and fatigue during exercise. However, exercise-induced ROS may regulate beneficial skeletal muscle adaptations, such as increased mitochondrial biogenesis. We therefore investigated the ...
Baumann Freerk T - - 2011
An allogeneic hematopoietic stem cell transplantation (HSCT) can have profound and lasting adverse effects on a patient's physical and psychological well- being. So far, only few studies have investigated the effectiveness of physical activity over the entire inpatient phase of an allogeneic HSCT. PURPOSE: We performed a randomized controlled study ...
Kelly Luke A - - 2011
PURPOSE:: To determine the effect of foot orthoses on neuromuscular control and the aerobic cost of running. METHODS:: Twelve recreational athletes ran for 1 hour on a treadmill at a constant velocity (i.e. 10% higher than their first ventilatory threshold) with and without custom-molded foot orthoses, in a counterbalanced order. ...
Umpierre Daniel - - 2011
Regular exercise improves glucose control in diabetes, but the association of different exercise training interventions on glucose control is unclear. To conduct a systematic review and meta-analysis of randomized controlled clinical trials (RCTs) assessing associations of structured exercise training regimens (aerobic, resistance, or both) and physical activity advice with or ...
Miyamoto Tadayoshi - - 2011
We have reported that minute ventilation [[Formula: see text]] and end-tidal CO(2) tension [[Formula: see text]] are determined by the interaction between central controller and peripheral plant properties. During exercise, the controller curve shifts upward with unchanged central chemoreflex threshold to compensate for the plant curve shift accompanying increased metabolism. ...
Andersson Gustav - - 2011
Tenocytes produce substance P (SP), and its receptor (neurokinin-1 receptor (NK-1R)) is expressed throughout the tendon tissue, especially in patients with tendinopathy and tissue changes (tendinosis) including hypercellularity and vascular proliferation. Considering the known effects of SP, one might ask whether SP contributes to these changes. To test whether development ...
Caudwell Phillipa - - 2011
Investigations of the impact of physical activity on appetite control have the potential to throw light on the understanding of energy balance and therefore, upon body weight regulation and the development of obesity. Given the complexity of the landscape influencing weight regulation,research strategies should reflect this complexity. We have developed ...
Bourke Liam - - 2011
Bourke L, Thompson G, Gibson DJ, Daley A, Crank H, Adam I, Shorthouse A, Saxton J. Pragmatic lifestyle intervention in patients recovering from colon cancer: a randomized controlled pilot study. To investigate the feasibility of a pragmatic lifestyle intervention in patients who had recently completed surgery and chemotherapy for colon ...
Dideriksen K J - - 2011
Sarcopenia is a well-known phenomenon in elderly individuals and resistance exercise together with sufficient amino acid (AA) availability has proved to be a counteractive implement. However, the source of AA and supplement timing require further investigation. The objective was to compare muscle protein synthesis (MPS) to intakes of whey and ...
Trost Barry M - - 2011
Pd-catalyzed asymmetric prenylation of oxindoles to afford selectively either the prenyl or reverse-prenyl product has been demonstrated. Control of the regioselectivity in this transformation is governed by the choice of ligand, solvent, and halide additive. The resulting prenylated and reverse-prenylated products were transformed into ent-flustramides and ent-flustramines A and B. ...
Smith Catherine - - 2011
Purpose. Regular exercise is considered important for long-term health outcomes and fatigue management in persons with multiple sclerosis (MS); however, little is known about the experiences of individuals with MS-related fatigue, who participate in community-based exercise activities. The aim of this study was to describe the experiences of people with MS-related ...
Layne Andrew S - - 2011
Strength training induces muscle remodeling and may improve insulin responsiveness. This study will quantify the impact of resistance training on insulin sensitivity in subjects with the metabolic syndrome and correlate this with activation of intramuscular pathways mediating mitochondrial biogenesis and muscle fiber hypertrophy. Ten subjects with the metabolic syndrome (MS) ...
Karthikbabu S - - 2011
Objective: To examine the effects of trunk exercises performed using the physio ball as against the plinth, on trunk control and functional balance in patients with acute stroke. Design: An observer-blinded pilot randomized controlled trial. Subjects: Thirty patients with acute stroke (mean post-stroke duration 12 (95% confidence interval (CI) 2-34) ...
Söderberg J - - 2011
The main aim of this study was to evaluate the short-term effects of daily eccentric exercises on functional pain-free hand strength in subjects with long-term lateral epicondylalgia. Forty-two subjects with lateral epicondylalgia were randomly assigned either to a 6-week home exercise regimen receiving eccentric training for their wrist extensors and ...
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