PURPOSE: To determine if particular values clarification exercises included in a patient decision aid had discernible impact on postdecisional regret in patients with early-stage prostate cancer. METHODS: A multicenter randomized controlled trial compared 2 versions of a computerized patient decision aid: only structured information compared to the structured information plus ...

Unfavourable effects on the respiratory and the cardiovascular systems from short-term and long-term inhalation of air pollution are well documented. Exposure to freshly generated mixed combustion emissions such as those observed in proximity to roadways with high volumes of traffic and those from ice-resurfacing equipment are of particular concern. This ...

The influence of physical exercise on the effects elicited by homocysteine on glutamate uptake and some parameters of oxidative stress, namely thiobarbituric acid-reactive substances, 2',7'-dichlorofluorescein (H(2)DCF) oxidation, as well as enzymatic antioxidant activities, superoxide dismutase, catalase and glutathione peroxidase in rat cerebral cortex were investigated. Wistar rats received subcutaneous administration ...

Strenuous exercise induces muscle damage due to a highly increased generation of free radicals and inflammatory response and therefore, in this type of exercise, it is important to reduce both oxidative stress and inflammation, at least their negative aspects. The purpose of this study was investigate, for the first time, ...

Hypercholesterolemia is one of the cardiovascular risk factors sensitive to preventive and control interventions. Here we created a hypercholesterolemia model to investigate the effect of the long term aerobic exercise (swimming) on the hemorheology of rats fed with high-fat diet. We found that the rats fed with high-fat diet developed ...

This study examined the acute effects of a single dose of an antioxidant (AO; Lactaway(®)containing pycnogenol) on time to fatigue (TTF). Nine trained cyclists [mean ± SD age 35 ± 10 yrs; body mass 71.6 ± 10.2 kg; VO(2)peak 63 ± 11 ml/kg/min] performed on two separate occasions a continuous ...

The risk of accidental falls and fall-related injuries increases with age. Regular physical exercises can delay the age-related changes affecting postural balance and reduce the risk of falls. Although Tai Chi (TC) has become a popular exercise among the elderly, does regular TC exercise lead to fewer falls and fall-related ...

The prescription of an effective therapeutic exercise program requires the right dosage of the right exercise, at the right time for that patient. The therapist must understand and apply training principles effectively in the presence of pathology, injury, or otherwise unhealthy tissue. The intervention goal is to close the gap ...

OBJECTIVE: International guidelines recommend short- (SABA) or long-acting b-agonists for the prevention of bronchoconstriction after exercise (EIB) in patients with exercise-induced asthma (EIA). However, other drugs are still in discussion for the prevention of EIB. We investigated the efficacy of a combination of inhaled sodium cromoglycate and the β-mimetic drug ...

Abstract The purpose of this study was to determine the effects of short-term normoxic and hypoxic exercise on plasma endothelin-1 and nitric oxide levels, and the relationship of arterial compliance and pulmonary artery pressure to endothelin-1. Seven endurance-trained males completed two incremental and two steady-state exercise tests performed at ventilatory ...

ABSTRACT: BACKGROUND: Ingestion of creatine (Cr) and glycerol (Gly) has been reported to be an effective method in expanding water compartments within the human body, attenuating the rise in heart rate (HR) and core temperature (Tcore) during exercise in the heat. Despite these positive effects, a substantial water retention could ...

Exercising in hot environments results in a rise in core body temperature; an effect associated with impaired performance over a variety of exercise modes and durations. Precooling has become a popular strategy to combat this impairment, as evidence has shown it to be an effective method for lowering pre-exercise core ...

ABSTRACT Research demonstrates a positive effect of aerobic exercise on cognitive functioning in older adults. Unfortunately, aerobic exercise is often contraindicated for older adults due to cardiovascular and functional limitations. Low-intensity strengthening exercise may offer a practical alternative, but the neuropsychological benefits and potential neurophysiological mechanisms are less well understood. ...

This study compared the effects of resistance exercise (RE) intensities on blood glucose (GLUC) of individuals without (ND) and with type-2 diabetes (T2D). Nine individuals with T2D and ten ND performed: 1) RE-circuit at 23% of one repetition maximum (1RM) (RE_L); 2) RE-circuit at 43%1RM (RE_M); and 3) control session ...

There are little data on the optimization of high-intensity aerobic interval exercise (HIIE) protocols in patients with chronic heart failure (CHF). Therefore, we compared acute cardiopulmonary responses to 4 different HIIE protocols to identify the optimal one. Twenty men with stable systolic CHF performed 4 different randomly ordered single HIIE ...

This review systematically synthesized current evidence on the effects of lower limb reciprocal pedalling exercise on motor function poststroke. Detailed analysis of single studies in the review revealed multiple instances of heterogeneity including outcome measures; therefore we decided to avoid undertaking a single, potentially misleading meta-analysis. We found that despite ...

The current review outlines the under-appreciated effects of physical exercise on the course of psychiatric disorders, focussing on recent findings from animal and human research. Several studies have shown that regular physical exercise is significantly beneficial for psychiatric patients both on a biological and a psychological level. Positive effects of ...

This paper reviews the therapeutically beneficial effects of progressive resistance exercise (PRE) on Parkinson's disease (PD). First, this paper discusses the rationale for PRE in PD. Within the first section, the review discusses the central mechanisms that underlie bradykinesia and muscle weakness, highlights findings related to the central changes that ...

The aim of this study was to examine the effects of ionised and non-ionised compression tights on sprint and endurance cycling performance. Using a randomised, blind, crossover design, 10 well-trained male athletes (age: 34.6 ± 6.8 years; height: 1.80 ± 0.05 m; body mass: 82.2 ± 10.4 kg; VO2max: 50.86 ...

Many studies have reported on the detrimental effects of early life adversity and the beneficial effects of exercise on brain function. However, the molecular mechanisms that underpin these various effects remain poorly understood. The advent of advanced proteomic analysis techniques has enabled simultaneous measurement of protein expression in a wide ...

There is growing interest in promoting health for people with disabilities, yet evidence regarding community-based interventions is sparse. This paper describes the design details of a randomized controlled trial (RCT) that will test the effectiveness of a multi-component behaviorally based, intervention to promote exercise adoption (over 6months) and maintenance (up ...

Workplace snacking can contribute to obesity. Exercise reduces chocolate cravings but effects on chocolate consumption are unknown. This study investigated the effect of brief exercise on ad libitum consumption during breaks in a computerised task. Seventy-eight regular chocolate eaters, age: 24.90±8.15years, BMI: 23.56±3.78kg/m(2) abstained for 2days. They were randomly assigned ...

Different exercise paradigms show differential effects on various forms of memory. We hypothesize that the differential effects of exercises on memory performance are caused by different neuroplasticity changes in relevant brain regions in response to different exercise trainings. We examined the effects of treadmill running (TR) and wheel running (WR) ...

The use of exercise interventions to manage cancer-related fatigue (CRF) is a rapidly developing field of study. However, results are inconsistent and difficult to interpret across the literature, making it difficult to draw accurate conclusions regarding the true effectiveness of exercise interventions for CRF management. The aims of this study ...

BACKGROUND: Depression is a distressing side effect of cancer and its treatment. In the general population, exercise is an effective antidepressant. OBJECTIVE: We conducted a systematic review and meta-analysis to determine the antidepressant effect of exercise in cancer survivors. Data Sources: In May, 2011, we searched MEDLINE, PsycInfo, EMBASE, CINAHL, ...

Spinocerebellar ataxia type 1 (SCA1) is a fatal neurodegenerative disease caused by expansion of a translated CAG repeat in Ataxin-1 (ATXN1). To determine the long-term effects of exercise, we implemented a mild exercise regimen in a mouse model of SCA1 and found a considerable improvement in survival accompanied by up-regulation ...

Experimental research has produced evidence in recent years underlying the beneficial effects that exercise can have in preventing and deceleration of the development of Parkinson disease. These beneficial effects are exerted through various mechanisms such as neuroprotection, neurotransmission, plasticity, neurogenesis, homeostasis, and neurotrophic factors. Studies on clinical application at an ...

ABSTRACT: BACKGROUND: Improving the lifestyle of overweight and obese adults is of increasing interest in view of its role in several chronic diseases. Interventions aiming at overweight or weight-related chronic diseases suffer from high drop-out rates. It has been suggested that Motivational Interviewing and more frequent and more patient-specific coaching ...

Spaccarotella, KJ and Andzel, WD. Building a beverage for recovery from endurance activity: A review. J Strength Cond Res 25(11): 3198-3204, 2011-Recovery beverages are commonly used by endurance and team-sport athletes during the time between exercise sessions. Practical recommendations on the optimal nutrient composition of these drinks and timing of ...

This study investigated the effects of high-dose large neutral amino acid (LNAA) supplementation on attenuating fatigue-induced decrements in exercise and motor skill performance in Australian Rules Football (ARF) players. Fifteen subelite ARF players participated in 3 testing sessions separated by 7 days. Players completed an initial control trial involving a reactive ...

Abstract Aging is associated with a progressive loss of muscle mass, strength, and function, a condition known as sarcopenia, which represents an important risk factor for physical disability in elderly. The mechanisms leading to sarcopenia are still largely unknown, and no specific therapy is presently available to counteract its onset ...

OBJECTIVE: To assess the short- and long-term effects of addition of exercise to a very low calorie diet (VLCD) on low-grade inflammation in obese patients with type 2 diabetes mellitus (T2DM). METHODS: Twenty seven obese, insulin-dependent T2DM patients followed a 4-month VLCD with (n=13) or without (n=14) exercise and were ...

The search for an extended understanding of the causes of depression, and for the development of additional effective treatments is highly significant. Clinical and pre-clinical studies suggest stress is a key mediator in the pathophysiology of depression. Exercise is a readily available therapeutic option, effective as a first-line treatment in ...

Compression garments (CGs) provide a means of applying mechanical pressure at the body surface, thereby compressing and perhaps stabilizing/supporting underlying tissue. The body segments compressed and applied pressures ostensibly reflect the purpose of the garment, which is to mitigate exercise-induced discomfort or aid aspects of current or subsequent exercise performance. ...

This paper sets out to clarify the unique features of exercise addiction. It begins by examining how this addiction can be distinguished from compulsions and impulse control disorders both of which, like an addiction, involve excessive behavior that creates adverse effects. Assessment of exercise addiction also requires that clinicians be ...

A snapshot of current evidence from 6 randomised controlled trials for the effects of short bouts of high-impact exercises in 256 women via meta-analysis reveals that ample osteogenic response could be realised at the femoral neck and trochanter of premenopausal women with rest-inserted bouts of few mechanical bone loading cycles. ...

Aims: Insulin resistance and visceral adiposity are predisposing factors for fatty liver disease. The main objectives of this study were 1) to compare the effects of caloric restriction alone (CR) or together with moderate-intensity aerobic exercise training (CR+EX) on liver enzymes, a surrogate marker of liver injury, in obese metabolic ...

An increase in intrahepatic triglyceride (IHTG) content is the hallmark of nonalcoholic fatty liver disease (NAFLD) and is strongly associated with insulin resistance and dyslipidemia. Although regular aerobic exercise improves metabolic function, its role in regulating fat accumulation in the liver is incompletely understood, and human data are scarce. Results ...

STUDY DESIGN: Systematic review with meta-analysis. OBJECTIVE: To pool and summarize the published research evidence examining if the combination of therapeutic exercise and joint mobilization is more beneficial than therapeutic exercise alone in patients with shoulder dysfunction. BACKGROUND: Therapeutic exercise is an effective intervention for patients with shoulder dysfunction which ...

Exercise-based cardiac rehabilitation (CR) remains an underused tool for secondary prevention post-myocardial infarction (MI). In part, this arises from uncertainty regarding the efficacy of CR, particularly with respect to reinfarction, where previous studies have failed to show consistent benefit. We therefore undertook a meta-analysis of randomized controlled trials (RCTs) to ...

Research on the performance effects of acute carbohydrate supplementation is comprehensive. Here we present the first meta-analytic review of this research. Methods: Eighty-eight randomized crossover studies in which carbohydrate supplements were consumed with or without protein before and/or during exercise provided 155 estimates for performance effects in time-to-exhaustion tests or ...

Lifestyle intervention programs encompassing exercise and healthy diets are an option for the treatment and management of obesity and type 2 diabetes and have long been known to exert beneficial effects on wholebody metabolism, in particular leading to enhanced insulin-sensitivity. Obesity is associated with increased risk of several illnesses and ...

PURPOSE OF REVIEW: Consensus statements about the care of people with cystic fibrosis (CF) recommend exercise as part of a wider management strategy. Many of these recommendations are based on high-quality evidence that regular exercise improves some important clinical outcomes, such as lung function and quality of life. However, the ...

Endurance swimming is known to increase duodenal calcium absorption in normal rats and bone strength in estrogen-deficient rats. Because the stress resulting from forced training often attenuates the stimulatory effect of exercise, swimming in an inescapable chamber should reveal both the positive effect of the exercise and the negative effect ...

BACKGROUND: Evidence is emerging of the combined effects of psychosocial and environmental determinants on exercise. PURPOSE: This study aims to examine the moderating effects of convenience, facilities at places of worship, access, crime/safety, and neighborhood characteristics on the relationship between exercise and psychosocial needs satisfaction (autonomy, competence, and relatedness). METHODS: ...

Regular exercise reduces the risk of chronic metabolic and cardiorespiratory diseases, in part because exercise exerts anti-inflammatory effects. However, these effects are also likely to be responsible for the suppressed immunity that makes elite athletes more susceptible to infections. The anti-inflammatory effects of regular exercise may be mediated via both ...

It is well established that physical exercise can enhance hippocampal-dependent forms of learning and memory in laboratory animals, commensurate with increases in hippocampal neural plasticity (brain-derived neurotrophic factor [BDNF] mRNA/protein, neurogenesis, long-term potentiation [LTP]). However, very little is known about the effects of exercise on other, non-spatial forms of learning ...

Exercise enhances general health. However, its effects on neurodegeneration are controversial, and the molecular pathways in the brain involved in this enhancement are poorly understood. Here, we examined the effect of long-term moderate treadmill training on adult male rats cortex and hippocampus in order to identify the cellular mechanisms behind ...

Immediate effects of an exercise with the vocal tract semi-closed. To investigate the immediate effects of the phonation exercise in a straw in individuals with and without vocal fold lesions. Prospective study. 48 individuals, aged between 18 and 55 years participated in the study, and they were distributed into two ...

The present paper has proposed two methods for obtaining the linear correlation of the baroreflex system without measurement of blood pressure. One is based on the pulse wave transit time which needs both the electrocardiogram and the photoplethysmogram. The other is based on the photoplethysmogram only. The results from the ...