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Climie Rachel - - 2014
BackgroundCentral hemodynamics help to maintain appropriate cerebral and other end-organ perfusion, and may be altered with ageing and type 2 diabetes mellitus (T2DM). We aimed to determine the associations between central hemodynamics and brain structure at rest and during exercise in people with and without T2DM.MethodsIn a sample of people ...
Ellis Michael J MJ Division of Neurosurgery, Pan Am Clinic, University of Manitoba , Winnipeg, Manitoba , Canada - - 2014
Abstract Primary objective: To present a novel pathophysiological approach to acute concussion and post-concussion syndrome (PCS). Research design: Review of the literature Methods and procedures: PubMed searches were performed to identify articles related to the pathophysiology and treatment of concussion and PCS. Relevant articles that contributed to the primary objective ...
Tan Can Ozan CO From the Cardiovascular Research Laboratory, Spaulding Rehabilitation Hospital, Department of Physical Medicine and Rehabilitation, Harvard Medical School (C.O.T., J.A.T.); The Micheli Center for Sports Injury Prevention, Division of Sports Medicine, Boston Children's Hospital, Department of Pediatrics and Orthopedics, Harvard Medical School (W.P.M.); and Department of Physical Medicine and Rehabilitation, Harvard Medical School, Spaulding Rehabilitation Hospital, Massachusetts General Hospital Sport Concussion Clinic, Red Sox Foundation and Massachusetts General Hospital Home Base Program (G.L.I.). - - 2014
A substantial number of people who sustain a mild traumatic brain injury report persistent symptoms. Most common among these symptoms are headache, dizziness, and cognitive difficulties. One possible contributor to sustained symptoms may be compromised cerebrovascular regulation. In addition to injury-related cerebrovascular dysfunction, it is possible that prolonged rest after ...
Berger Nikolas - - 2014
BackgroundAn increasing number of studies suggest that physical activity can alleviate symptoms of ADHD in children. In adults there are currently insufficient data available on this subject. Interestingly, ADHD and forms of excessive exercising have both been shown to occur more frequently in adult athletes. The aim of the present ...
Zhang Li L Department of Rehabilitation, Huashan Hospital, Fudan University, Shanghai 200040, - - 2014
Autophagy is a degradative mechanism for cellular proteins and organelles, but its role in the nervous system is still not clear. In the present study, we found that exercise pretreatment and p38 inhibition had influence on autophagic process after cerebral ischemia, contributing to their neuroprotective effects. We examined the levels ...
Jacotte-Simancas Alejandra A Universitat Autònoma de Barcelona, Institut de Neurociències, Bellaterra, Spain ; - - 2014
The biochemical and cellular events that lead to secondary neural damage after traumatic brain injury (TBI) contribute to long-term disabilities, including memory deficits. There is a need to search for single and/or combined treatments aimed at reducing these TBI-related disfunctions. The effects of citicoline and of voluntary physical exercise in ...
Reinecke Natália Lopes NL Renal Division, Department of Medicine, Federal University of São Paulo, São Paulo, - - 2014
Reports about exercise performance in autosomal dominant polycystic kidney disease (ADPKD) are scarce. We aimed to evaluate exercise capacity and levels of nitric oxide and asymmetric dimethylarginine (ADMA) in normotensive patients with ADPKD. Prospective controlled cohort study. 26 patients with ADPKD and 30 non-ADPKD control participants (estimated glomerular filtration rate>60mL/min/1.73m(2), ...
Lippi Giuseppe G U.O. di Diagnostica Ematochimica, Dipartimento di Patologia e Medicina di Laboratorio, Azienda Ospedaliero-Universitaria di Parma, Parma, - - 2014
Although it is widely acknowledged that physical activity confers several health benefits, it remains uncertain whether strenuous and physically demanding exercise might determine biological effects that might turn to be ultimately unfavorable for health. Copeptin and midregion proadrenomedullin (MR-proADM) are emerging cardiovascular and stress biomarkers, but little is known about ...
Coquart Jérémy B JB Faculté des Sciences du Sport et de l'Education Physique, EA 3832, Centre d'Etudes des Transformations des Activités Physiques et Sportives, Université de Rouen, Boulevard Siegfried, 76821, Mont Saint Aignan Cedex, France, - - 2014
Maximal or peak oxygen uptake ([Formula: see text] and [Formula: see text], respectively) are commonly measured during graded exercise tests (GXTs) to assess cardiorespiratory fitness (CRF), to prescribe exercise intensity and/or to evaluate the effects of training. However, direct measurement of CRF requires a GXT to volitional exhaustion, which may ...
Bandyopadhyay Amit A Sports and Exercise Physiology Laboratory, Department of Physiology, University of Calcutta University College of Science and Technology, Kolkata, - - 2014
Direct estimation of VO<formula>_{2}</formula>max involves labourious, exhaustive, hazardous, time consuming and expensive experimental protocols. Hence, application of various indirect protocols for prediction of VO<formula>_{2}</formula>max has become popular, subject to proper population-specific standardisation of the indirect protocol. Application of Fox (1973) protocol in male sedentary university students of Kolkata, India led ...
Orcy Rafael R School of Physiotherapy, Universidade Católica de Pelotas, Pelotas, Brazil; School of Medicine, Universidade Federal de Pelotas, Pelotas, - - 2014
Previous studies have suggested that exercise during hemodialysis (HD) could increase the efficacy of solute removal, although this hypothesis has not been conclusively evaluated. The goal of this study was to compare the removal of low-molecular weight solutes between HD sessions, with and without aerobic exercise. It was a controlled ...
Aparicio V A VA Department of Physiology, School of Pharmacy and Faculty of Sport Sciences, and Institute of Nutrition and Food -Technology, University of Granada, - - 2014
We investigated the renal effects of a high-intensity exercise (HIE) program based on strength training. 20 Wistar rats were randomly assigned to 2 experimental groups performing HIE or control over 12 weeks. Urinary volume, pH, citrate and calcium, and plasma urea, total proteins, creatinine, albumin, lactate dehydrogenase, creatine kinase (CK), ...
Micalos Peter S PS School of Biomedical Sciences, Charles Sturt University, Bathurst, NSW, - - 2014
The purpose of this research was to assess the functional brain activity and perceptual rating of innocuous somatic pressure stimulation before and after exercise rehabilitation in patients with chronic pain. Eleven chronic pain patients and eight healthy pain-free controls completed 12 weeks of supervised aerobic exercise intervention. Perceptual rating of ...
Collins Larisa R LR Program in Neuroscience, Department of Psychology, Bates College, 4 Andrews Road, Lewiston, Maine, USA 04240. Electronic address: - - 2013
Circulating levels of brain-derived neurotrophin factor (BDNF) are known to be affected by aerobic exercise. As the previous research focus in humans has been to examine peripheral BDNF levels through blood, serum, and platelet assay, the present study investigated the association between basal urinary BDNF concentration and indices of aerobic ...
Kordi Mehdi M European Astronaut Centre, European Space Agency, Linder Hoehe, Cologne, - - 2013
The European Space Agency conducted an astronaut selection campaign in 2008-09 which attracted over 8000 applicants. Of those, 45 made the final assessment stage: the medical examination (MEX). This retrospective, observational study reports exercise and fitness data, lipid profiles and other results of interest from the blood and urine samples ...
Kirkman Danielle L - - 2013
Background/Aims: According to mathematical modeling, intradialytic exercise of sufficient intensity and duration implemented in the second half of dialysis should be as efficacious as increasing dialysis time for dialysis adequacy. This assumption has not been tested in vivo. Methods: In this controlled trial, 11 hemodialysis (HD) patients (mean (SD) age ...
Ma Guodong - - 2013
It is documented that exercise can increase serum cardiac troponins in adults and adolescents; however, there is a lack of related studies concerning the release of cardiac troponins in children. This study investigated the influence of table tennis training on cardiac biomarkers in children. Twenty-eight male children performed six 10-min ...
Paglialonga Fabio - - 2013
Intradialytic exercise has been poorly investigated in pediatric patients on chronic hemodialysis (HD). The aim of this study was to assess the acceptability, safety and efficacy of intradialytic exercise in children and young adults on HD. The intradialytic exercise program consisted of 30-min sessions of intra-HD exercise using a cycloergometer ...
Amorim Mayra Z - - 2013
We investigated differences in sex responses in serum CK activity and renal function measured by glomerular filtration rate (GFR) after an exercise session. Twenty-two healthy and trained volunteers (11 males and 11 females) performed 17 resistance exercises with 3 × 12 repetitions in a circuit training fashion. Subjects provided blood samples prior ...
Junglee Naushad Ali - - 2013
Unaccustomed strenuous physical exertion in hot environments can result in heat stroke and acute kidney injury (AKI). Both exercise-induced muscle damage and AKI are associated with the release of interleukin-6 but whether muscle damage causes AKI in the heat is unknown. We hypothesized that muscle damaging exercise, prior to exercise ...
Koikawa Natsue N School of Health and Sports Science, Juntendo University, Inzai, Chiba - - 2013
Wheat gluten hydrolysate (WGH) is a food ingredient, prepared by partial enzymatic digestion of wheat gluten, which has been reported to suppress exercise-induced elevation of serum creatinine kinase (CK) activity. However, its effects on athletic performance have not yet been elucidated. This is the presentation of an experiment performed on ...
Park Sung-Ji - - 2013
Background: The aim of this study was to assess contractile reserve (CR) in patients with severe aortic regurgitation (AR), and potential clinical applications of CR in minimally symptomatic patients. Methods and Results: Symptom-limited treadmill exercise echocardiography was performed in 58 asymptomatic or mildly symptomatic patients with chronic severe AR (male 69%, 50±14 ...
Dabidi Roshan V - - 2013
We evaluated the effect of Creatine (Cr) supplementation on muscle fatigue and physiological indices after intermittent swimming bouts in trained swimmers. Sixteen healthy non-elite swimmers (19±4 years, 75±12 kg) were randomly assigned into two groups of either Cr supplementation or placebo and performed six repeated sprints swimming bouts of 50-m ...
Hiraki Koji - - 2013
The aim of this study was to determine whether a single moderate-intensity exercise session induces renal injury based on various parameters that reflect kidney dysfunction, including urinary L-type fatty acid-binding protein (L-FABP). Adult outpatients (n = 31) with chronic kidney disease (CKD) not receiving renal replacement therapy participated in this ...
Tsitsimpikou Christina - - 2013
Creatinine phosphokinase (CPK) and lactate dehydrogenase (LDH) are important biological markers of various myocardial disorders and exercise-induced muscle damage. Lycopene, on the other side, is a natural anti-oxidant with protective action against cardiovascular risk. Fifteen anaerobically trained athletes with elevated LDH and CPK baseline levels were enrolled in this study ...
Attarzadeh Hosseini Seyyed Reza - - 2013
So far, there have been a few and incoherent results about the effects of physical activities. Fasting in Ramadan has an effect on the level of osmolarity and the concentration of serum electrolytes both in active and inactive females. The aim of this study was to observe the changes of ...
Sokal Paweł - - 2013
Contact of humans with the earth, either directly (e.g., with bare feet) or using a metal conductor, changes their biochemical parameters. The effects of earthing during physical exercise are unknown. This study was carried out to evaluate selected biochemical parameters in subjects who were earthed during cycling. In a double-blind, ...
Ribeiro Ronaldo R Federal University of São - - 2013
Patients with chronic kidney disease (CKD) when subjected to resistance exercise (RE) show substantial improvements in many functions, especially those related to the cardiovascular system, respiratory, muscular and quality of life (QOL). There are no evaluations of the impact of exercise simple and feasible in patients with CKD associated with ...
Maheshwari Vaibhav - - 2012
ABSTRACT: BACKGROUND: Maintenance hemodialysis (HD) patients universally suffer from excess toxin load. Hemodiafiltration (HDF) has shown its potential in better removal of small as well as large sized toxins, but its efficacy is restricted by inter-compartmental clearance. Intra-dialytic exercise on the other hand is also found to be effective for ...
Francescato M P - - 2012
The hypothesis that variability in individual's cardiac output response affects the kinetics of pulmonary O(2) uptake ( [Formula: see text] ) was tested by investigating the time constants of cardiac output (Q˙) adjustment (τ(Q)), of PCr splitting (τ(PCr)), and of phase II pulmonary O(2) uptake ( [Formula: see text] ) ...
Keays S L - - 2012
BACKGROUND: Following anterior cruciate ligament (ACL) rupture, the knee becomes unstable with alterations in joint kinematics including anterior tibial displacement (ATD), and internal tibial rotation. Therapeutic exercises that promote faulty kinematics should be discouraged, especially early post-reconstruction, to avoid graft stretching and possibly longer-term osteoarthritis. Our study aimed to compare ...
Chiang Kwo-Tsao - - 2012
Military aircrew members undergo regular aviation physiology training, including hypobaric chamber flight to demonstrate the effects of hypoxia at altitude on human physiology and to strengthen hypoxia awareness. Premature near syncope under hypoxia will jeopardize flight safety. However, the causes of such abnormality may not be apparent. We present a ...
Lippi Giuseppe - - 2012
Abstract Background: Strenuous exercise may trigger acute complications, such as exertional rhabdomyolysis and gastrointestinal complaint. As less is known about the potential renal impairment after long distance running, we assessed creatinine and neutrophil gelatinase associated lipocalin (NGAL) in serum (sNGAL) and urine (uNGAL) before and after an ultramarathon. Methods: The ...
Hejazi Seyed Majid Akhavan SM Department of Rehabilitation Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia. - - 2012
Polymyositis (PM) is an idiopathic inflammatory myopathy manifested by proximal limb muscles weakness, elevated creatinin kinase, electromyography changes, and muscle inflammation in biopsy. We report an instance of intensive rehabilitation therapy in a patient with clinically active polymyositis. A 19-year-old female patient, diagnosed with 'electromyography and biopsy proven' polymyositis for ...
Wang Jong-Shyan - - 2011
The cytotoxic functions of NKs (natural killer cells) are critical in enabling the immune system to cope efficiently with malignancy. In the present study, we compared how various exercise regimens without/with hypoxia influence phenotypic characteristics of NK subsets and cytotoxicity of NKs to NPCs (nasopharyngeal carcinoma cells). A total of ...
Bolger Claire - - 2011
Exercise-induced bronchoconstriction (EIB) is a common condition in both individuals with asthma and otherwise healthy elite athletes. Although excessive water loss by peripheral airways during hyperpnea is regarded as the initial trigger for EIB, the cascade of events that follows remains unclear. Our goal was to establish whether transient disruption ...
Sossdorf Maik - - 2011
Cell-derived procoagulant microparticles (MP) might be able to contribute to exercise-induced changes in blood hemostasis. : This study aimed to examine (i) the concentration and procoagulant activity of cell-derived MP after a moderate endurance exercise and (ii) the differences in the release, clearance, and activity of MP before and after ...
Viloria María - - 2011
The aim of the present study was to determine the effect of moderate exercise on the production and secretion of IgA in mouse duodenum, on lymphocyte levels in the lamina propria, and on gene expression encoding for cytokines that regulate the synthesis of α-chain of IgA and the expression of ...
Boehme Fanny - - 2011
Alcohol consumption during pregnancy can result in a myriad of health problems in the affected offspring ranging from growth deficiencies to central nervous system impairments that result in cognitive deficits. Adult hippocampal neurogenesis is thought to play a role in cognition (i.e. learning and memory) and can be modulated by ...
Drummond Micah J MJ University of Texas Medical Branch, Department of Nutrition and Metabolism, Division of Rehabilitation Sciences, Sealy Center on Aging, 301 Univ. Blvd., Galveston, TX 77555-1144, USA. - - 2011
Amino acid transporters and mammalian target of rapamycin complex 1 (mTORC1) signaling are important contributors to muscle protein anabolism. Aging is associated with reduced mTORC1 signaling following resistance exercise, but the role of amino acid transporters is unknown. Young (n = 13; 28 ± 2 yr) and older (n = ...
Kelly Karen R - - 2011
Low-glycemic index diets and exercise independently improve glucose tolerance and reduce diabetes risk. However, the combined effect of a low-glycemic index diet and exercise on inflammation and glucose metabolism is not known. Therefore, we randomized 28 insulin-resistant adults (age: 66 ± 1 y; BMI: 34.2 ± 0.7 kg · m(-2)) ...
Nam Sung Min - - 2011
In this study, we investigated the effects of treadmill exercise on calretinin (CR), a marker of early postmitotic neurons, immunoreactivity in the dentate gyrus (DG) of Zucker diabetic fatty (ZDF) rats, before or after diabetes onset, and Zucker lean control (ZLC) rats. For this study, 6-week-old ZLC and prediabetic ZDF ...
Belke Darrell D - - 2011
Swim-training exercise in mice leads to cardiac remodeling associated with an improvement in contractile function. Protein O-linked N-acetylglucosamine (O-GlcNAcylation) is a posttranslational modification of serine and threonine residues capable of altering protein-protein interactions affecting gene transcription, cell signaling pathways, and general cell physiology. Increased levels of protein O-GlcNAcylation in the ...
Turner James E - - 2011
This study investigated whether changes in the cellular composition of blood during exercise could partly account for observations of exercise-induced changes in lymphocyte oxidative stress markers. Markers of oxidative stress were assessed before and after 60 min of intense treadmill running. Samples were collected from 16 men (means ± SD: ...
Moebius-Winkler Sven - - 2011
Abstract Endothelial progenitor cells (EPCs) are thought to participate in endothelial cell regeneration and neovascularization in either a direct or an indirect way. The number of circulating EPCs is influenced by many factors like disease status, medication, age, and fitness level and is an independent predictor of disease progression and ...
Nielsen Joachim - - 2011
Although glycogen is known to be heterogeneously distributed within skeletal muscle cells, there is presently little information available about the role of fibre types, utilization and resynthesis during and after exercise with respect to glycogen localization. Here, we tested the hypothesis that utilization of glycogen with different subcellular localizations during ...
Rebelo António N - - 2011
Rebelo, AN, Ascensão, AA, Magalhães, JF, Bischoff, R, Bendiksen, M, and Krustrup, P. Elite futsal refereeing: activity profile and physiological demands. J Strength Cond Res 25(4): 980-987, 2011-The purpose of this study was to determine the physiological demands and to establish the relationship between activity profile and endurance capacity of ...
Billaut François - - 2011
: The anticipation of exercise-induced stress influences performance during continuous exercise. However, not all exercise is continuous. This study explores the influence of prior knowledge of sprint number on mechanical work, surface EMG, and RPE during repeated-sprint exercise (RSE). : Fourteen athletes performed three RSE in random order. In one ...
Hinchado M D - - 2011
Recently, the terms "stress mediators" or "danger signals" have come to be used to describe endogenous molecules that can be released in stress situations and activate the innate immune system even in the absence of antigenic stimuli. There is evidence suggesting that extracellular heat shock proteins of 72 kDa (eHsp72), ...
Itoh Tatsuki - - 2011
Exercise is reported to inhibit neuronal apoptotic cell death in the hippocampus and improve learning and memory. However, the effect of exercise on inhibition of neuronal apoptosis surrounding the area of damage after traumatic brain injury (TBI) and the improvement of cerebral dysfunction following TBI are unknown. Here, we investigate ...
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