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Nowiński Adam - - 2013
Dyspnoea and decreased exercise tolerance are symptoms of acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Anaemia is a risk factor for reduced functional capacity and dyspnoea in stable COPD. There is limited information about the impact of anaemia on functional capacity and dyspnoea of patients during AECOPD. The aim ...
Zebrowska Aleksandra - - 2013
The objective of the study was to investigate whether a blood pressure increase during static exercises might affect the left ventricular function and whether a possible pressure overload might decrease cardio-respiratory adaptation to aerobic exercise in power lifting athletes. Nine resistance-trained athletes and ten age-matched untrained men participated in high ...
Wiseman Rachel L - - 2013
Healthy individuals are known to have significantly reduced oxygen saturations at rest when acutely exposed to moderate altitudes, such as during commercial flight. There is a paucity of data on the response of healthy individuals to exercise at these altitudes. The aim of this study was to establish the normal ...
Nachbauer Wolfgang - - 2013
Friedreich ataxia (FRDA) is caused by a GAA repeat expansion in the FXN gene leading to reduced expression of the mitochondrial protein frataxin. Recombinant human erythropoietin (rhuEPO) is suggested to increase frataxin levels, alter mitochondrial function and improve clinical scores in FRDA patients. Aim of the present pilot study was ...
Mørkeberg Jakob - - 2013
The delivery of oxygen is the limiting factor during whole-body endurance exercise in well-trained individuals, so manipulating the amount of hemoglobin in the blood results in changes in endurance exercise capacity. Athletes began using novel erythropoiesis-stimulating agents well before they were approved for medical use. Older manipulation practices, such as ...
Otto James M JM Division of Surgery and Interventional Science, c/o 4th Floor, Rockefeller Building, 21 University Street, London WC1E 6DE, UK. - - 2013
The ability of the cardiorespiratory system (heart, lungs, blood) to deliver oxygen to exercising skeletal muscle constrains maximum oxygen consumption V˙O2max, with cardiac output and the concentration of oxygen-carrying haemoglobin ([Hb]) being key limiting parameters. Total blood volume (BV) is the sum of the plasma volume (PV) and the total ...
Humberstone-Gough Clare E CE Department of Physiology; Australian Institute of Sport ; Canberra, Australia ; Faculty of Health, University of Canberra , Canberra, - - 2013
Live High:Train Low (LHTL) altitude training is a popular ergogenic aid amongst athletes. An alternative hypoxia protocol, acute (60-90 min daily) Intermittent Hypoxic Exposure (IHE), has shown potential for improving athletic performance. The aim of this study was to compare directly the effects of LHTL and IHE on the running ...
Pun Matiram M Mountain Medicine Society of Nepal (MMSN), C/O Nepal International Clinic (NIC), Lal durbar, GPO BOX 3596, Kathmandu, Nepal. - - 2013
The 18th International Hypoxia Symposia, Lake Louise, Alberta, Canada, February 26-March 02, 2013, covered molecular basis of hypoxic responses (e.g., hypoxia inducible factor, nitrite, nitrate, and hemoglobin) and integrative physiology (e.g., exercise physiology, cerebral blood flow responses, live-high train-low, and population genetics). Free communications and poster sessions covered scientific areas ...
Otto James M JM Division of Surgery and Interventional Science, University College London, 21 University Street, London WC1E 6DE, UK. - - 2013
Preoperative anaemia and low exertional oxygen uptake are both associated with greater postoperative morbidity and mortality. This study reports the association among haemoglobin concentration ([Hb]), peak oxygen uptake (V˙O2 peak) and anaerobic threshold (AT) in elective surgical patients. Between 1999 and 2011, preoperative [Hb] and cardiopulmonary exercise tests were recorded ...
Sun Jian Ling - - 2012
The aim of this study was to determine the diagnostic value of treadmill exercise test (TET) in patients with coronary heart disease (CHD) by comparing the diagnostic conclusions with coronary angiography (CAG). Patients (445) with CHD and suspected CHD underwent TET and CAG, and the corresponding diagnostic conclusions were compared. ...
Norris Jacob N - - 2012
Few studies have evaluated high altitude headache (HAH) and acute mountain sickness (AMS) in military populations training at moderate (1,500-2,500 m) to high altitudes (>2,500 m). In the current study, researchers interviewed active duty personnel training at Marine Corps Mountain Warfare Training Center. Participants were asked about HAH and AMS ...
Trevizani Gabriela Alves - - 2012
BACKGROUND: Physiological aging leads to cardiac autonomic dysfunction, which is associated with the onset and worsening of cardiovascular disease and an increased risk of death. Currently, physical exercise is considered a cardioprotective strategy and more research is needed on its benefit on cardiac autonomic function. OBJECTIVE: To evaluate the autonomic ...
Choi Kyung Mook - - 2012
Context:Low levels of soluble receptor for advanced glycation end-products (sRAGE) have been linked to systemic inflammation and vascular complications in patients with type 2 diabetes mellitus (T2DM).Objective:We examined the effects of exercise on sRAGE and its association with diverse cardiometabolic risk factors and indicators of atherosclerosis in patients with T2DM.Design, ...
Loganathan Rajprasad - - 2012
One of the fundamental biochemical defects underlying the complications of diabetic cardiovascular system is elevation of diacylglycerol (DAG) and its effects on protein kinase C (PKC) signaling. It has been noted that exercise training attenuates poor cardiac performance in Type 1 diabetes. However, the role of PKC signaling in exercise-induced ...
Sovtic Aleksandar D - - 2012
BACKGROUND: We evaluated the exercise capacity of children with cystic fibrosis to determine whether ventilatory limitation associated with static hyperinflation is related with decreased exercise capacity, thus predisposing these children to arterial hypoxaemia during progressive exercise. METHODS: Thirty-seven children aged 8 - 17 years underwent spirometry, bodyplethysmography and cardiopulmonary exercise ...
Liu Sam - - 2012
Background: Previous studies examining the relationship between exercise dose and post-exercise hypotension (PEH) have employed a limited range of exercise duration and subject age. We extended the dose-response curve by studying two intensities of prolonged exercise that may produce a greater magnitude of PEH and reveal age differences in the ...
Swank Ann M - - 2012
The prognostic ability of a single measurement of peak oxygen uptake (VO(2)) is well established in patients with chronic heart failure. The relation between a change in peak VO(2) and clinical outcomes is not well defined. This investigation determined whether an increase in peak VO(2) was associated with a lower ...
Kusunose Kenya - - 2012
OBJECTIVE: Left atrial (LA) function is an important contributor to cardiac function in a variety of disease states and especially with exercise. The purpose of this study was to assess the role of LA function in the left ventricular (LV) filling pressure (E/e') response to exercise and exercise tolerance in ...
Faselis Charles - - 2012
Prehypertension is likely to progress to hypertension. The rate of progression is determined mostly by age and resting blood pressure but may also be attenuated by increased fitness. A graded exercise test was performed in 2303 men with prehypertension at the Veterans Affairs Medical Centers in Washington, DC. Four fitness ...
Nepal O - - 2012
Backgroud The oxygen saturation of haemoglobin is reduced in high altitude-living organisms. Increase in the hematocrit is responsible for rise in the hemoglobin concentration so that the oxygen carrying capacity in the hypobaric hypoxic subject is elevated. Objectives To compare two different high altitude populations, in order to study the ...
Glei Dana A - - 2012
To compare the effects of relaxation practice and other exercise on a multisystem measure of physiologic dysregulation in a national sample of older Taiwanese. The study was a cross-sectional survey. The study was conducted in Taiwan. A population-based sample of 1036 adults aged 53 and older completed an in-home interview ...
Kusy K - - 2012
We studied relationships between age and aerobic capacity in three groups of subjects adhering to different exercise modalities. A total of 203 men aged 20-90 years were examined: 52 speed-power track and field athletes (SP), 89 endurance runners (ER) and 62 untrained individuals (UT). Maximal exercise characteristics were obtained during ...
Buitrago S - - 2012
ABSTRACT: The purpose of the study was to compare the mechanical impact and the corresponding physiological responses of four different and often practically applied resistance training methods (RTM). Ten healthy male subjects (27.3 ± 3.2 years) experienced in resistance training performed one exhausting set of bench press exercise until exhaustion ...
Renfree Andrew - - 2012
This study examined the determinants of pacing strategy and performance during self-paced maximal exercise. Eight well-trained cyclists completed two 20-km time trials. Power output, rating of perceived exertion (RPE), positive and negative affect, and iEMG activity of the active musculature were recorded every 0.5 km, confidence in achieving preexercise goals ...
Thanassoulis George - - 2012
Exercise blood pressure (BP) is an important marker of left ventricular hypertrophy, incident hypertension, and future cardiovascular events. Although impaired vascular function is hypothesized to influence the BP response during exercise, limited data exist on the association of vascular function with exercise BP in the community. Framingham Offspring cohort participants ...
Feitosa L A S - - 2012
INTRODUCTION: The gold-standard method for the diagnosis of exercise-induced bronchospasm (EIB) is an exercise test combined with spirometry. However, this test is expensive, time consuming and requires specialized equipment and trained personnel. Exhaled nitric oxide (eNO) is a fast, easy, noninvasive method for the diagnosis of EIB. The aim of ...
Geda Yonas E YE Department of Psychiatry and Psychology, Mayo Clinic, Scottsdale, AZ 85259, USA. - - 2012
To examine the association between computer use, physical exercise, aging, and mild cognitive impairment (MCI). The Mayo Clinic Study of Aging is a population-based study of aging and MCI in Olmsted County, Minnesota. The study sample consists of a random sample of 926 nondemented individuals aged 70 to 93 years ...
Peltonen Juha E - - 2012
We used near-infrared spectroscopy to investigate whether leg and arm skeletal muscle and cerebral deoxygenation differ during incremental cycling exercise in men with type 1 diabetes (T1D, n=10, mean±SD age 33±7 years) and healthy control men (matched by age, anthrometry, and self-reported physical activity, CON, n=10, 32±7 years) to seek ...
Scrivener Katharine - - 2012
BACKGROUND: . Predicting walking outcomes poststroke is a challenge for clinicians. OBJECTIVE: . To identify the extent to which exercise dose (repetitions of leg movements) in the first week of a comprehensive stroke unit stay predicts discharge mobility. METHODS: . A cohort study was conducted on 200 consecutive people admitted ...
Marcuccio Elisa - - 2012
In patients with surgically repaired tetralogy of Fallot (TOF), reported peak oxygen consumption (VO(2)) is decreased compared with control subjects. The measurement of exercise cardiac output (CO) could be a useful adjunct for assessing cardiovascular fitness. There are few data assessing noninvasive CO, cardiac index (CI), and stroke volume (SV) ...
Pomp Sarah - - 2012
The aim of the study was to examine the relationship between depressive symptoms and physical exercise by unveiling how outcome expectancies regarding exercise and positive exercise experience could mediate between depressive symptoms and exercise. A longitudinal study included 178 cardiac and orthopedic rehabilitation patients in Germany. Patients responded to psychometric ...
De Roia Gabriela - - 2012
Ageing is associated with a functional decline of the oxidative metabolism due to progressive limitations of both O(2) delivery and utilization. Priming exercise (PE) increases the speed of adjustment of oxidative metabolism during successive moderate intensity transitions. We tested the hypothesis that such improvement is due to a better matching ...
Mooney Mitchell - - 2012
This study aimed to quantify the influence of neuromuscular fatigue (NMF) via flight time to contraction time ratio (FT:CT) obtained from a countermovement jump on the relationships between yo-yo intermittent recovery (level 2) test (yo-yo IR2), match exercise intensity (HIR m·min and Load™·min) and Australian football (AF) performance.Thirty seven data ...
Mehta R - - 2012
Marathon running can increase circulating cardiac troponin above the diagnostic criteria for myocardial infarction. We determined whether prior-exercise experience (training history) might be related to the magnitude of immediate post-race troponin release following completion of the London Marathon in a group of non-elite runners. Using a prospective study design, 52 ...
Leclair E - - 2012
This study aimed to examine if the faster pulmonary oxygen uptake (VO(2p) ) phase 2 in children could be explained by increased O (2) availability or extraction at the muscle level. For that purpose, O (2) availability and extraction were assessed using deoxyhemoglobin (HHb) estimated by near-infrared spectroscopy during moderate-intensity ...
Gravel Hugo - - 2012
Exercise testing can highlight repolarisation abnormalities in adults with coronary artery disease. Late after Kawasaki disease (KD), increased QT dispersion (QTd) has been reported on resting ECG in children, but there are no reported studies of QTd during exercise. Our objective was to determine the pattern of QTd response to ...
Lopes A J AJ Setor de Provas de Função Respiratória, Universidade do Estado do Rio de Janeiro, Rua Araguaia 1266, Rio de Janeiro, RJ, Brazil. - - 2012
Cardiopulmonary exercise testing (CPET) plays an important role in the assessment of functional capacity in patients with interstitial lung disease. The aim of this study was to identify CPET measures that might be helpful in predicting the vital capacity and diffusion capacity outcomes of patients with thoracic sarcoidosis. A longitudinal ...
Meyerspeer Martin - - 2012
By improving spatial and anatomical specificity, localized spectroscopy can enhance the power and accuracy of the quantitative analysis of cellular metabolism and bioenergetics. Localized and nonlocalized dynamic (31)P magnetic resonance spectroscopy using a surface coil was compared during aerobic exercise and recovery of human calf muscle. For localization, a short ...
Blank A Christian - - 2012
The management of patients with isolated congenital complete atrioventricular block (CCAVB) has changed during the last decades. The current policy is to pace the majority of patients based on a variety of criteria, among which is limited exercise capacity. Data regarding exercise capacity in this population stems from previous publications ...
Shantsila Eduard - - 2012
Eur J Clin Invest 2012 ABSTRACT: Background  Monocytes are important mediators in the pathophysiology of cardiovascular disease, but only scarce data are available on biological and methodological factors affecting their levels. Design  Three monocyte subsets, CD14(++)  CD16(-)  CCR2+ (Mon1), CD14(++)  CD16(+)  CCR2(+)  (Mon2), CD14(+)  CD16(+)  CCR2(-) (Mon3), and monocyte-platelet aggregates ...
O'Callaghan Frances - - 2012
Studies involving animals and older adults suggest that physical activity (PA) might lead to improved cognitive ability in general, and enhanced intelligence scores (IQ) in particular. However, there are few studies involving young persons and none controlling for the possibility that those with better cognitive skills are more likely to ...
Llewellyn Tamra L - - 2012
AIM: Endothelial function is a predictor of cardiovascular health and is improved with exercise training. However, it is not clear how exercise acutely affects endothelial function. Previous studies present conflicting results, resulting from varied exercise protocols and ambiguity in data analysis after exercise. The aims of this study were to ...
Manika Katerina - - 2012
Background. Pulmonary hypertension (PH) is an often complication of severe cystic fibrosis (CF); however, data on the presence and impact of pulmonary vasculopathy in adult CF patients with milder disease, is very limited. Aim. To investigate, for the first time, the impact of systolic pulmonary arterial pressure (PASP) on maximal ...
Gennser Mikael - - 2012
Recent studies have indicated that exercise before diving significantly reduces the number of circulating bubbles and the risk of decompression sickness. However, the most effective time delay between exercise and dive is not clear; the present aim was to resolve this. In a hyperbaric chamber, 10 men were compressed to ...
Czaprowski D - - 2012
Background: Muscle shortening is often present in children with idiopathic scoliosis and may be the object of physiotherapy. Aim of the study: Prospective randomized single-blinded evaluation of hamstring-H, rectus femoris-RF and iliopsoas-IP flexibility in children under the 6-week therapeutic programme consisting of one physiotherapy session per week and daily home ...
Faulhaber Martin - - 2012
Intermittent hypoxic exposure (IHE) has been shown to induce aspects of altitude acclimatization which affect ventilatory, cardiovascular and metabolic responses during exercise in normoxia and hypoxia. However, knowledge on altitude-dependent effects and possible interactions remains scarce. Therefore, we determined the effects of IHE on cardiorespiratory and metabolic responses at different ...
Bisson Etienne J - - 2012
Fatiguing exercises used across studies to induce alterations in postural control are diverse and may explain the different findings reported. This study aimed to compare the effects of two types of fatiguing plantarflexion exercises on postural control on a firm and a compliant surface. Ten healthy young men (29 ± ...
Sieverdes John C - - 2011
BACKGROUND: Habitual physical activity (PA) is associated with higher cardiorespiratory fitness values, but additional information is needed on the contributions of specific types and amounts of PA. Therefore the main aim of this study was to analyze the heart and lung function of a large cohort of men and compare ...
King Matthew S - - 2011
In this descriptive case series, 80 soldiers from Fort Campbell, Kentucky, with inhalational exposures during service in Iraq and Afghanistan were evaluated for dyspnea on exertion that prevented them from meeting the U.S. Army's standards for physical fitness. The soldiers underwent extensive evaluation of their medical and exposure history, physical ...
Logemann J A - - 2012
The oropharyngeal swallow involves a rapid, highly coordinated set of neuromuscular actions beginning with lip closure and terminating with opening of the upper esophageal sphincter. Evaluation of the oropharyngeal swallow usually involves the use of a modified barium swallow radiographic study with the goals of (i) defining the patient's swallow ...
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