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Kalani Rizwan - - 2006
Chronic inflammation is associated with the aging process and numerous age-related pathologies. We evaluated the effects of age, caloric restriction (CR), and exercise on plasma C-reactive protein (CRP), interleukin-6, and total antioxidant capacity in Fisher 344 rats. The inflammatory markers were analyzed using enzyme-linked immunosorbent assays (ELISA), while total antioxidant ...
Seo Arnold Y - - 2006
Hepatic aging may involve alterations in redox status, resulting in enhanced oxidant production and changes in specific signaling pathways that lead to a pro-inflammatory response. The authors investigated whether mild calorie restriction and long-term voluntary exercise could attenuate these changes. Four groups of male Fischer 344 rats were compared: young ...
Galassetti Pietro R - - 2006
BACKGROUND: In humans, the main sources of reactive oxygen species (ROS), the molecules causing oxidative stress, are mitochondrial superoxide ions and neutrophil-derived oxidative radicals. Circulating antioxidants contribute to the protection against oxidative stress. Although the formation of ROS and secretion of antioxidants are independently regulated by exercise and diet, little ...
Qiao D - - 2006
To determine the effect of intermittent anaerobic exercise on physical endurance, antioxidant capacity, and lipid peroxidation of brain, heart, and skeletal muscles in mice. Mice were made to perform intermittent (with short or long rest intervals) anaerobic swimming on six consecutive days. Body weight was monitored. Tissue total antioxidant capacity ...
Deruisseau Keith C - - 2006
Diaphragmatic antioxidant enzymes are upregulated following acute and long-term treadmill exercise, but the effect of lifelong voluntary exercise (E) on diaphragmatic antioxidants is unknown. Therefore, 10-week old Fisher 344 rats were assigned to either: (a) sedentary ad libitum (AL) fed (24AL; n = 6); (b) E + 8% caloric restriction ...
Steinberg Jean Guillaume - - 2006
This study compares the changes in four blood markers of exercise-induced oxidative stress in response to exercise protocols commonly used to explore the global muscle performance at work (maximal incremental cycle) and endurance to fatigue of selected muscles (static handgrip and thumb adduction). Cycling and static exercises allow the muscle ...
Dadjour Mahmoud Farshbaf - - 2006
An ultrasonic treatment system, using a TiO2 photocatalyst, was used to disinfect Legionella pneumophila. A kinetic study of the process indicates that TiO2 significantly improves the disinfection process. The concentrations of viable cells were reduced to 6% of the initial concentrations in the presence of 0.2g/ml TiO2 after a 30 ...
Sacheck Jennifer M - - 2006
IL-6 mediates many aspects of the exercise-induced acute-phase response, including upregulation of antioxidant defenses. Moreover, IL-6 synthesis is regulated in part by oxidative stress. This investigation tested the hypothesis that an IL-6-mediated acute-phase response after exercise provides negative-feedback protection against exercise-induced oxidative stress. Healthy young (n = 16, 26.4 +/- ...
Prieto Ana I - - 2006
Increasing evidence suggests that oxidative stress may play a significant role in causing microcystin (MCs) toxicity not only in mammals, but also in fish. MCs are a family of cyclic peptide toxins produced by some species of freshwater cyanobacteria (blue-green algae). Among the microcystins, MC-LR is the most extensively studied. ...
Finaud J - - 2006
Physical training is known to increase the antioxidant defence system and reduce exercise-induced oxidative stress. However, intense physical aerobic and anaerobic training and competition such as those imposed on professional rugby players, can induce an increase of oxidative stress which can be implicated with the arrival of overtraining. The aim ...
Duckles Sue Piper - - 2006
Mitochondrial dysfunction has been implicated as a cause of age-related disorders, and the mitochondrial theory of aging links aging, exercise, and diet. Endothelial dysfunction is a key paradigm for vascular disease and aging, and there is considerable evidence that exercise and dietary restriction protect against cardiovascular disease. Recent studies demonstrate ...
Wilson Mark A - - 2006
The beneficial effects of polyphenol compounds in fruits and vegetables are mainly extrapolated from in vitro studies or short-term dietary supplementation studies. Due to cost and duration, relatively little is known about whether dietary polyphenols are beneficial in whole animals, particularly with respect to aging. To address this question, we ...
Hagobian Todd A - - 2006
PURPOSE: This study tested the hypothesis that antioxidant supplementation would attenuate plasma cytokine (IL-6, tumor necrosis factor (TNF)-alpha), and C-reactive protein (CRP) concentrations at rest and in response to exercise at 4300-m elevation. METHODS: A total of 17 recreationally trained men were matched and assigned to an antioxidant (N = ...
Dékány M - - 2006
Muscular exercise results in an increased production of free radicals and other forms of reactive oxygen species (ROS). Further, developing evidence implicates cytotoxins as an underlying etiology of exercise-induced stimuli in muscle redox status, which could result in muscle fatigue and/or injury. Two major classes of endogenous protective mechanisms (enzymatic ...
Hatao Hidekazu - - 2006
The lung could be the target organ to cellular damage, since it is directly exposed to high concentrations of oxygen. Acute exercise and age would be an added challenge to the lung, and therefore, we investigated alterations of major lung antioxidant enzymes (manganese-superoxide dismutase, Mn-SOD; copper-zinc-SOD, Cu-Zn-SOD; glutathione peroxidase, GPX; ...
Ohno, Hideki
OHNO, H., KIZAKI, T., SUZUKI, K., HITOMI, Y., WATANABE, A., OOKAWARA, T., SUZUKI, K., HAGA, S., SAITO, D., RADAK, Z. and Li Li JI, Physical Exercise and Extracellular Superoxide Dismutase:Antiatherogenic Effects. Adv. Exerc. Sports Physiol., Vol.9, No.2 pp45-53, 2003. It has been well known that strenuous of endurance exercise causes ...
Toshinai, Koji
TOSHINAI, K., OHNO, H., BAE, A.Y., IWASHITA, T., KOSEKI, S. and HAGA, S., Effect of Different Intensity and Duration of Exercise with the Same Total Oxygen Uptake on Lipid Peroxidation and Antioxidant Enzyme Levels in Human Plasma. Adv. Exerc. Sports Physiol., Vol.4, No.2 pp65-70, 1998. The present study was undertaken ...
Radak, Zsolt
RANDK, Z., OGONOVSZKY, H., TAYLOR, A.w. and FOTO, S., Exercise-induced Alteration of Oxidative DAN Damage. Adv. Exerc. Sports Physiol., Vol.7, No.2 pp43-46, 2001. Reactive oxygen and mitrogen specise generated in physiologicak processes are continuously attatcking unclear and mitochondrial DNA. Oxidative DNA damage can have seriou outcomes through the induction of ...
Toshinai, Koji
TOSHINAI, K., HAGA, S., MIYAZAKI, H., TAKEMASA, T., NOMURA, T., KIZAKI, T. and OHNO, H., Effects of Different Intensity and Duration of Exercise with the Same Oxygen Consumption on the Ability of Neutrophils to Generate Superoxide Anion Radicals in Humans. Adv. Exerc. Sports Physiol., Vol.6, No.3 pp91-95, 2000. The aim ...
Morillas-Ruiz J M - - 2006
Polyphenols are of increasing interest to consumers and food manufacturers for several reasons. Commonly referred to as antioxidants (they are the most abundant antioxidants in our diets), they may prevent various oxidative stress-related diseases, such as cancer, cardiovascular disease, inflammation and others. Physical activity is known to induce oxidative stress ...
Traverse Jay H - - 2006
Exercise is associated with an increase in oxygen flux through the mitochondrial electron transport chain that has recently been demonstrated to increase the production of reactive oxygen species (ROS) in skeletal muscle. This study examined whether exercise also causes free radical production in the heart. We measured ROS production in ...
Johnston Carol S - - 2006
BACKGROUND: Vitamin C is a cofactor in the biosynthesis of carnitine, a molecule required for the oxidation of fatty acids. A reduction in the ability to oxidize fat may contribute to the reported inverse relationship between vitamin C status and adiposity. To examine this possibility, we conducted a preliminary trial ...
Galán Ana I - - 2006
Free radicals and oxidative stress are involved in the pathogenic mechanisms of cardiovascular disease (CVD), diabetes and cancer. Exercise is a useful strategy for preventing CVD but in elderly persons it can enhance oxidative stress, which is why some studies recommend antioxidant supplementation for exercising elderly subjects. This intervention study ...
Williams Melvin - - 2006
This is the fourth in a series of six articles to discuss the major classes of dietary supplements (vitamins; minerals; amino acids; herbs or botanicals; metabolites, constituents/extracts, or combinations). The major focus is on efficacy of such dietary supplements to enhance exercise or sport performance.
Ascensão António - - 2006
Endurance training (ET) and adriamycin (ADR) treatment are two conditions that have been described as triggering metabolic alterations within the myocardium. ADR is an anti-neoplastic agent with notorious cardiotoxicity, most likely because it increases oxidative stress. ET and/or ADR treatment can induce metabolic and signaling alterations affording cross-tolerance against several ...
Bagchi Debasis - - 2006
Edible berry extracts rich in anthocyanins possess a broad spectrum of therapeutic, pharmacologic and anti-carcinogenic properties. Six berry extracts (wild blueberry, bilberry, cranberry, elderberry, raspberry seeds and strawberry), singly and in combination, were studied in our laboratories for antioxidant efficacy, cytotoxic potential, cellular uptake and anti-angiogenic properties. Combinations of edible ...
Fry Andrew C - - 2006
The purpose of this study was to determine if supplementation with a liquid multi-vitamin/mineral would improve anaerobic exercise performance. Fourteen resistance-trained men performed a 30-second cycle sprint and one set of squat exercise on 2 separate days before and following 8 weeks of supplementation with either a liquid multi-vitamin/ mineral ...
Davison Gareth W - - 2006
Maximal exercise in normoxia results in oxidative stress due to an increase in free radical production. However, the effect of a single bout of moderate aerobic exercise performed in either relative or absolute normobaric hypoxia on free radical production and lipid peroxidation remains unknown. To examine this, we randomly matched ...
Zoppi Claudio C - - 2006
Exercise training is known to induce an increase in free radical production potentially leading to enhanced muscle injury. Vitamins C and E are well known antioxidants that may prevent muscle cell damage. The purpose of this study was to determine the effects of these supplemental antioxidant vitamins on markers of ...
Knez Wade L - - 2006
At least 30 minutes of moderate-intensity physical activity accumulated on most, preferably all days is considered the minimum level necessary to reduce the risk of developing cardiovascular disease. Despite an unclear explanation, some epidemiological data paradoxically suggest that a very high volume of exercise is associated with a decrease in ...
Kingsley Michael - - 2006
Phosphatidylserine (PtdSer) is a ubiquitous phospholipid species that is normally located within the inner leaflet of the cell membrane. PtdSer has been implicated in a myriad of membrane-related functions. As a cofactor for a variety of enzymes, PtdSer is thought to be important in cell excitability and communication. PtdSer has ...
Choi Eun-Young - - 2006
AIMS AND METHODS: This study investigated the effect of Allium vegetable intake on the antioxidative activity and on the plasma cholesterol profile during exercise in rats. Ninety rats were fed either a control diet or a diet with added Allium sativum (AS), Allium cepa (AC), Allium fistulosum (AF), or Allium ...
Kostaropoulos I A - - 2006
Exercise increases the production of reactive oxygen species, which may damage a number of cell constituents. Organisms have developed a sophisticated antioxidant system for protection against reactive oxygen species. Our aim was to compare the adaptive responses of antioxidant mechanisms and the blood redox status of two groups of athletes, ...
Tauler Pedro - - 2006
BACKGROUND: Exhaustive exercise induces oxidative stress. The cellular antioxidant defence systems have demonstrated great adaptation to chronic exercise. AIM: To establish the influence of the antioxidant diet supplementation on the erythrocyte and lymphocyte antioxidant enzyme activities in athletes at basal and post-exercise levels. METHODS: Fifteen amateur trained male athletes were ...
Sureda Antoni - - 2005
Hydrogen peroxide (H2O2) could induce oxidative damage at long distance from its generation site and it is also an important signalling molecule that induces some genes related to oxidative stress. Our objective was to study the plasma and blood cells capability to detoxify H2O2 after intense exercise and its correlation ...
Co┼čkun Sule - - 2005
The purpose of this study was to ascertain whether vitamin C supplementation during chronic exercise training alters rat brain antioxidant content. Female Wistar albino rats were exercised on a treadmill for 30 min/day for 6.5 weeks and were administered daily intraperitoneal injections of vitamin C (20 mg/kg). After the training ...
Schneider Cláudia Dornelles - - 2005
In 8 trained subjects (T) and 9 untrained subjects (UT), lipid peroxidation (LPO), total antioxidant capacity (TRAP), superoxide dismutase, catalase, and glutathione peroxidase (GPx) activities were measured in the blood before and after three different intensities of exercise on the treadmill, determined from ventilatory threshold and maximal oxygen uptake data, ...
Box W - - 2005
AIM: Exercise can conceivably increase concentrations of lipid peroxides (by producing oxidant stress) or decrease their concentrations (by accelerating peroxide breakdown). The net effect could depend on exercise intensity and nutritional antioxidant intake. METHODS: Recreationally trained, young adult women (n=18) consumed antioxidant-rich soy protein or antioxidant-poor whey protein for 4 ...
Tauler Pedro - - 2006
It has been reported that exercise induces oxidative stress and causes adaptations in antioxidant defences. The aim of this study was to determine the adaptations of lymphocytes to the oxidative stress induced by an exhaustive exercise. Nine voluntary male subjects participated in the study. The exercise was a cycling mountain ...
McAnulty Steven R - - 2005
OBJECTIVE: This study examined whether, daily fruit (blueberries) consumption (250 g) for three weeks or acute fruit ingestion (250 g) would attenuate angiotensin converting enzyme (ACE) activity and reduce oxidative stress in chronic cigarette smokers. METHODS: Twenty subjects were recruited and randomized into fruit or control groups. Blood samples and ...
Sapin M R - - 2005
Exogenous antioxidants, e.g. tocopherol, prevent undesirable changes in the thymus and accelerate its recovery after intensive physical exercise. Four weeks after the end of training (swimming) the general structure of the thymus and content of LPO products in rats treated with tocopherol corresponded to the control values, in contrast to ...
Kakarla Pushpalatha - - 2005
This study investigated the onset of age-related changes in the myocardial antioxidant defense system (ADS) and the vulnerability of the myocardium to oxidative stress following exercise training. Few studies have investigated the influence of the most prevalent life-prolonging strategy physical exercise, on the age-dependent alterations in the myocardial antioxidant enzyme ...
Chicco Adam J - - 2006
Doxorubicin (Dox) is a highly effective antineoplastic antibiotic associated with a dose-limiting cardiotoxicity that may result in irreversible cardiomyopathy and heart failure. The purpose of this study was to examine the effects of low-intensity exercise training (LIET) during the course of Dox treatment on cardiac function, myosin heavy chain expression, ...
Uner M - - 2005
This study was performed as a complimentary to our previous study regarding the chemical stability of ascorbyl palmitate (AP) in solid lipid nanoparticles (SLN), nanostructured lipid carriers (NLC) and for comparison, in nanoemulsion (NE) incorporated into a hydrogel produced by high pressure homogenization. AP is known as an effective antioxidant ...
Davison G W - - 2005
The purpose of this investigation was to determine the effects of antioxidant supplementation on DNA damage following exercise. Fourteen subjects were randomly assigned to one of two groups and required to ingest either antioxidants (400 mg alpha-lipoic acid, 200 mg co-enzyme Q10, 12 mg manganese, 600 mg vitamin C, 800 ...
Wang Jong-Shyan - - 2005
Exercise is linked with intensity-dependent immune response. Intracellular redox status is important in programmed cell death. This study, by closely examining 18 sedentary men who exercised moderately and severely (ie. 60% and 80% VO2max, respectively) for 40 min, investigated how exercise intensities influence intracellular redox status and oxidative stress-induced apoptosis ...
Venditti P - - 2005
We investigated effects of prolonged aerobic exercise and severe hyperthyroidism on indices of oxidative damage, susceptibility to oxidants, and respiratory capacity of homogenates from rat liver, heart and skeletal muscle. Both treatments induced increases in hydroperoxide and protein-bound carbonyl levels. Moreover, the highest increases were found when hyperthyroid animals were ...
Vento Máximo - - 2005
RATIONALE: Pure oxygen causes more oxidative stress than room air in resuscitation of asphyctic neonates, and consequently could be associated with increased tissue damage. OBJECTIVES: To compare damage caused to heart and kidneys on reoxygenation in severely asphyctic term neonates resuscitated with room air (RAR) or 100% oxygen (OxR). Nonasphyctic ...
Zhou S - - 2005
AIM: To investigate whether 4 weeks of oral supplementation with coenzyme Q10 (CoQ10) would increase its concentration in skeletal muscle, and affect aerobic power (VO2max) and oxygen consumption during submaximal exercise in healthy, physically active men. METHODS: Six volunteers with an average (+/-SD) age of 29.7+/-7.2 years and VO2max of ...
Karanth Jyothsna - - 2005
The purpose of this study was to determine the effect of dietary fat, carnitine supplementation, and exercise on oxidative damage and antioxidant status. Male Wistar rats (60 days old) were fed diets containing either hydrogenated fat (HF) or peanut oil (PO) with or without 0.5 mg % (of dry diet) ...
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