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Hayashi Miyuki - - 2012
AimsCatecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited arrhythmic disorder with a highly malignant clinical course. Exercise-stress test is the first-line approach to diagnose suspected individuals. We sought to elucidate the value of exercise-stress test for predicting mutations and future cardiac events in CPVT-family relatives.Methods and resultsThe present study included ...
Iguchi Masaki - - 2012
Conditions such as osteoarthritis, obesity, and spinal cord injury limit the ability of patients to exercise, preventing them from experiencing many well-documented physiologic stressors. Recent evidence indicates that some of these stressors might derive from exercise-induced body temperature increases. To determine whether whole-body heat stress without exercise triggers cardiovascular, hormonal, ...
Kennard John A - - 2012
In this study we compared two types of forced exercise-a low impact paradigm to minimize stress, which included speeds up to 10 m/min and a stressful high impact paradigm, with speeds up to 21 m/min. 150 male C57BL/6J mice were randomly assigned to the low impact, high impact, or sedentary ...
Minardi Giovanni - - 2012
We describe the case of a patient with typical chest pain but negative maximal bicycle exercise-electrocardiogram test and for whom significant coronary artery disease was hypothesized by a positive handgrip exercise test and demonstrated by coronary angiography. Despite negative exercise stress test, handgrip as well as other provocative tests have ...
Woods D R - - 2012
High altitude exposure normally leads to a marked natriuresis and diuresis. Acute mountain sickness is often associated with fluid retention, to which an elevated cortisol may contribute. Most investigators report a rise in resting cortisol with ascent, but little data exist regarding the cortisol response to a day trekking. We ...
Ren Zhuyin - - 2012
Pulmonary embolism is the third leading cause of death in hospitalized patients in the US. Vena cava filters are medical devices inserted into the inferior vena cava (IVC) and are designed to trap thrombi before they reach the lungs. Once trapped in a filter, however, thrombi disturb otherwise natural flow ...
Rontoyanni Victoria G - - 2012
Long-chain n-3 PUFA can lower blood pressure (BP) but their acute effects on cardiac output, BP and systemic vascular resistance (SVR) in response to dynamic exercise are uncertain. We compared the effects of high-fat meals rich in EPA (20 : 5n-3), DHA (22 : 6n-3) or oleic acid (control) on cardiac output, BP and ...
Pauliks Linda B - - 2012
Adult studies suggest a better functional outcome after aortic valve replacement with a pulmonary autograft compared with mechanical or homograft valves. Little is known about functional results after Ross surgery in growing children. This study reports formal exercise stress echocardiographic data from 26 pediatric Ross patients. A retrospective cohort study ...
Minett Geoffrey M - - 2012
This study examined the effects of pre-cooling duration on performance and neuromuscular function for self-paced intermittent-sprint shuttle running in the heat. Eight male, team-sport athletes completed two 35-min bouts of intermittent-sprint shuttle running separated by a 15-min recovery on three separate occasions (33°C, 34% relative humidity). Mixed-method pre-cooling was completed ...
Pinho Cleber A - - 2012
AIM: Physical exercise is important in the prevention and treatment of cardiovascular diseases. Nevertheless, controversy remains around type and intensity of effort required for significant biochemical protective changes. This study investigates two exercise protocols on ventricular oxidative parameters in rats post-infarction. MAIN METHODS: Thirty-six 2-month-old male Wistar rats were divided ...
Marshall Heather - - 2012
For many shark species, little information exists about the stress response to capture and release in commercial longline fisheries. Recent studies have used hematological profiling to assess the secondary stress response, but little is known about how, and to what degree, these indicators vary interspecifically. Moreover, there is little understanding ...
Bailey Stephen J - - 2012
The purpose of this investigation was to determine the influence of heat stress on the dynamics of muscle metabolic perturbation during high-intensity exercise. Seven healthy males completed single-legged knee-extensor exercise until the limit of tolerance on two separate occasions. In a randomized order the subjects underwent 40 min of lower-body ...
Chirico Erica N - - 2012
The aim of this study was to analyze the effects of exercise training on oxidative stress in sickle cell trait carriers. Plasma levels of oxidative stress [advanced oxidation protein products (AOPP), protein carbonyl, malondialdehyde (MDA), and nitrotyrosine], antioxidant markers [catalase, glutathione peroxidase (GPX), and superoxide dismutase (SOD)], and nitrite and ...
Repossini Alberto - - 2012
OBJECTIVESThe present study investigates early clinical and haemodynamic results with the Freedom SOLO bioprosthesis (FSB) for aortic valve replacement (AVR) in eight Italian institutions.METHODSFrom 2004 to 2008, a total of 229 patients [139 females (60.7%); mean age 74 ± 8 years, left ventricular (LV) ejection fraction >40%] underwent AVR with FSB. One ...
Basha P Mahaboob - - 2012
Regardless of the circumstantial evidences on the involvement of fluoride on the etiology and pathogenesis of fluorosis, several lines of evidences strongly indicate the influence of modulator factors such as duration of fluoride exposure, age, temperature, and physical activity. This study has been designed to investigate the combined influence of ...
Scheer Bernd Volker - - 2012
ABSTRACT: This is the first report of a runner with myasthenia gravis who completed an ultra endurance event. Myasthenia gravis, a neuromuscular disease that usually results in skeletal muscle weakness, which worsens with exercise and strenuous aerobic exercise, is generally contraindicated. Our runner completed a 220-km, 5-day ultramarathon and presented ...
Davison Gareth W - - 2012
Even though intense exercise has traditionally been associated with a statistically significant accumulation of blood-borne biomarkers of free radical-mediated lipid peroxidation, it remains to be determined if the oxidative stress response is biologically significant. To examine biological significance, we calculated the critical difference of selected biomarkers of oxidants-antioxidants in the ...
Garatachea N - - 2012
We examined hormonal and haematological parameters and the profile of mood states (POMS) in top level judoists undertaking a 7-week competitive training period in a real contest. Participants were 10 top level judoists belonging to the Spanish National Team. Training load was calculated by multiplying the training session intensity by ...
Nikolaidis Michalis G - - 2012
Twenty males ran either on a level treadmill (nonmuscle-damaging condition) or on a downhill treadmill (muscle-damaging condition). Blood and urine samples were collected before and after exercise (immediately after, 1h, 4h, 24h, 48h, and 96h). The following assays were performed: F(2)-isoprostanes in urine, protein carbonyls in plasma, glutathione, superoxide dismutase, ...
Weber Maria Helena - - 2012
Heat shock protein 70 (HSP70) is a chaperone that maintains protein conformation during heat stress. It has recently been observed that HSP70 may be released from cells in response to increased energy demand (e.g., exercise) and/or oxidative stress. Since HSP70 levels should change in response to athletic training, we have ...
Miwa H - - 2012
Background  Care of patients with functional gastrointestinal disorders (FGIDs) commonly includes offering guidance on diet, exercise, and other lifestyle factors, but there is little information available on the actual lifestyles of FGID sufferers. Methods  An internet questionnaire survey of 15 000 adult members of the general public in Japan who were ...
Cholewa Jason M - - 2012
ABSTRACT: Regular exercise is recommended as part of cystic fibrosis (CF) physiotherapy. Exercise delays the development of pulmonary disease in CF patients; however, the cellular mechanisms responsible for these improvements are unclear. This review expands upon the hypothesis that exercise improves CF pathophysiological ion dysregulation via purinergic and adrenergic pathways ...
Head Denise - - 2012
Chronic stress has well-documented negative effects on hippocampal structure and function, and has been suggested to contribute to age-related declines. In contrast, there is evidence that exercise has beneficial effects in older adults. The current investigation examined effects of lifetime stress on hippocampal volume and memory, the moderating role of ...
Donal Erwan - - 2012
BACKGROUND: Heart failure (HF) with a preserved (P) left ventricular (LV) ejection fraction (EF) is common, though its diagnosis and physiopathology remains unclear. We sought to analyse the myocardial characteristics at rest and during a sub-maximal exercise test in patients with HFPEF. METHODS AND RESULTS: Standardized sub-maximal exercise stress echocardiography ...
Jaisson Maxime - - 2012
INTRODUCTION: On account of its specific biodynamics, the disc joint located at the very heart of the joint can impact every constituent of the manducatory system. The disc is deformed when subjected to stresses exerted by the muscles of mastication which it partly absorbs and partly redistributes. MATERIALS AND METHODS: ...
Silveira Paulo Cesar Lock - - 2012
INTRODUCTION: The aim of the study was to evaluate the effects of TPU together with DMSO on oxidative stress parameters after eccentric exercise. METHODS: Thirty and six animals were divided in control; eccentric exercise (EE); EE+saline gel 0.9%; EE+TPU 0.8W/cm(2); EE+DMSO gel; EE+TPU+DMSO gel and submitted to one 90-min downhill ...
Romeih Soha - - 2012
OBJECTIVESIn patients with pulmonary atresia with intact ventricular septum (PAIVS), biventricular repair is considered to be the optimal treatment option in the absence of significant right ventricular (RV) hypoplasia. However, long-term clinical outcome studies are limited. We evaluated exercise capacity and cardiac function during pharmacological stress in children and young ...
Wingo Jonathan E - - 2012
ABSTRACT: Cardiovascular drift, the progressive increase in heart rate and decrease in stroke volume that begins after ~ 10 min of prolonged, moderate-intensity exercise, is associated with decreased maximal oxygen uptake, particularly during heat stress. Consequently, increased heart rate reflects increased relative metabolic intensity during prolonged exercise in the heat ...
Kiuchi T - - 2012
In animals, chronic stress leads to the development of depression-like behavior and decreases neurogenesis and blood vessel density in hippocampus, whereas antidepressants increase adult neurogenesis in hippocampus. Regular exercise training also has antidepressant action and increases hippocampal neurogenesis; however, whether exercise-induced antidepressant action is related to hippocampal microvasculature is unclear. ...
Loenneke Jeremy P - - 2012
Objectives: Exercise to failure results in similar muscle protein synthesis responses, independent of intensity. However, low-intensity exercise likely requires more time under tension and those with injuries may be incapable of sustaining the mechanical stress to reach failure. Design: The purpose was to determine whether elastic knee wraps (KW) provide ...
McLeay Yanita - - 2012
Exercise-induced muscle damage (EIMD) is accompanied by localized oxidative stress / inflammation which, in the short-term at least, is associated with impaired muscular performance. Dietary antioxidants have been shown to reduce excessive oxidative stress; however, their effectiveness in facilitating recovery following EIMD is not clear. Blueberries demonstrate antioxidant and anti-inflammatory ...
Olszowska Maria - - 2012
Dobutamine stress testing is an important non-invasive method for evaluating patients with known or suspected coronary artery disease who are unable to adequately exercise. We present a case of a paradoxical, progressive bradycardia occurring with increasing doses of dobutamine that resulted in stress test interruption. (Cardiol J 2012; 19, 1: ...
Paulsen Gøran - - 2012
Exercise-induced muscle damage is an important topic in exercise physiology. However several aspects of our understanding of how muscles respond to highly stressful exercise remain unclear In the first section of this review we address the evidence that exercise can cause muscle damage and inflammation in otherwise healthy human skeletal ...
Okudan N - - 2012
This study examined the combined effects of swimming training and coenzyme Q10 (CoQ10) supplementation on exhaustive exercise-induced oxidative stress in rat heart. The study was carried out with 4-month-old young adult male Wistar rats. Sixty four rats were divided mainly into two groups: trained and control. Each group was further ...
Yu Szu-Hsien - - 2012
Previous studies reported divergent results on nutraceutical actions and free radical scavenging capability of ginseng extracts. Variations in ginsenoside profile of ginseng due to different soil and cultivating season may contribute to the inconsistency. To circumvent this drawback, we assessed the effect of major ginsenoside-Rg1 (Rg1) on skeletal muscle antioxidant ...
Ramadan Mohamed Zaki - - 2012
Objective: Although respiratory device is an essential item to protect the wearer from hazardous gases and dust, it tends to increase heat load on the workers. The goal of this paper was to select the appropriate respiratory devices that can be used in a harsh weather under different work-loads. Methods: ...
Vaturi Mordehay - - 2012
Patient gender can affect not only the clinical manifestations of coronary artery disease (CAD) but also the clinician's interpretation of the symptoms and results of exercise stress tests for management decisions. This may be true also for aortic stenosis (AS), given its many shared features with CAD and similar symptom-based ...
Liu Yuefei - - 2012
Exercise causes a variety of physiological and metabolic changes that can in turn reduce exercise tolerance. One of the potential mechanisms responsible for fatigue is "exercise-induced hyperammonemia". Previous studies have shown that supplementation with amino acids can increase training tolerance. The α-keto acids are biochemical analogs of amino acids and ...
Bhatt Hema - - 2012
This paper explores the extent of the physiological stresses of female workers at kitchen workstation while performing the various activities. For this a survey of eighty homemakers and experiment on sixteen respondents having similar physical and physiological parameters was done. Five activities in which the respondents faced maximum problems were ...
Viana Marcelo Tavares - - 2012
To analyze the impact of moderate physical exercise on the total and differential leukocyte counts and red blood cell count of 36 sixty-day-old adult male Wistar rats subjected to early malnourishment. The rats were divided in nourished (N - casein 17%) and malnourished groups (M - casein 8%) and thesegroups ...
Martinez-Campos Catalina - - 2012
Oxidative stress (OS) induced by acute exercise is reduced by chronic exercise. Ozone (O(3)) exposure produces OS. The aim of this study was to determine if aerobic exercise (AE) reduced OS produced by O(3). A pilot experiment was performed with male Wistar rats submitted to AE (trained to swim 90 min/day). ...
Harms-Ringdahl Mats - - 2012
DNA is constantly exposed to reactive oxygen species (ROS), spontaneously arising during the normal oxygen metabolism. ROS may result in temporary as well as permanent modifications in various cellular components such as lipids, proteins and DNA, which may have deleterious consequences. Demonstrating that a dietary supplementation of antioxidants can reduce ...
Falone Stefano - - 2012
Oxidative stress and neurotrophic support decline seem to be crucially involved in brain aging. Emerging evidences indicate the pro-oxidant methylglyoxal (MG) as a key player in the age-related dicarbonyl stress and molecular damage within the central nervous system. Although exercise promotes the overproduction of reactive oxygen species, habitual exercise may ...
Kanamori Satoru - - 2012
We sought to examine prospectively the difference in the association between incident functional disability and exercise with or without sports organization participation. The study was based on the Aichi Gerontological Evaluation Study (AGES) Cohort Study data. In October 2003, self-reported questionnaires were mailed to 29,374 non-disabled Japanese individuals aged 65 ...
Johnson Blair D - - 2012
Acute doses of elevated retrograde shear rate (SR) appear to be detrimental to endothelial function in resting humans. However, retrograde shear increases during moderate intensity exercise which also enhances post-exercise endothelial function. Since SR patterns differ with the modality of exercise, it is important to determine if augmented retrograde SR ...
Veskoukis Aristidis S - - 2012
Fruits, such as grapes, are essential food of the Mediterranean diet. Grape extracts have potent antioxidant and chemopreventive properties in vitro. Numerous studies have examined the effects of plant extract administration on redox status at rest in animals and humans but their results are controversial. However, there are no studies ...
Gomes Elisa Couto - - 2012
This review offers an overview of the influence of reactive species produced during exercise and their effect on exercise adaptation. Reactive species and free radicals are unstable molecules that oxidize other molecules in order to become stable. Although they play important roles in our body, they can also lead to ...
Ishikawa Yuji - - 2012
Exercise is recommended for the management of type 2 diabetes, but its effects on diabetic nephropathy (DN) are still unknown. We hypothesized that appropriate exercise improves early DN via attenuation of inflammation and oxidative damage. Type 2 diabetic KK-A(y) mice, a spontaneous DN model, underwent two different kinds of exercise ...
Greulich Simon - - 2012
Exercise electrocardiography (ECG) is frequently used in the work-up of patients with suspected coronary artery disease (CAD), however the accuracy is reduced in women. Cardiovascular magnetic resonance (CMR) stress testing can accurately diagnose CAD in women. To date, a direct comparison of CMR to ECG has not been performed. We ...
Golbidi Saeid - - 2012
The metabolic syndrome is a clustering of obesity, diabetes, hyperlipidemia, and hypertension that is occurring in increasing frequency across the global population. Although there is some controversy about its diagnostic criteria, oxidative stress, which is defined as imbalance between the production and inactivation of reactive oxygen species, has a major ...
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