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Vanhees L - - 2012
The beneficial effect of exercise training and exercise-based cardiac rehabilitation on symptom-free exercise capacity, cardiovascular and skeletal muscle function, quality of life, general healthy lifestyle, and reduction of depressive symptoms and psychosocial stress is nowadays well recognized. However, it remains largely obscure, which characteristics of physical activity (PA) and exercise ...
Burtscher M - - 2012
To study the effects of a supervised exercise program on serum gamma-glutamyl transferase (GGT), glycemic control and cardiovascular risk factors in pre-diabetic patients with isolated impaired fasting glucose (IFG) and those with IFG plus impaired glucose tolerance (IGT).Out of 60 pre-diabetic patients (30 with isolated IFG and 30 with IFG ...
Dimatelis J J JJ Department of Human Biology, Faculty of Health Sciences, University of Cape Town, Observatory 7925, South Africa. - - 2013
Animals subjected to maternal separation stress during the early stages of development display behavioural, endocrine and growth factor abnormalities that mirror the clinical findings in anxiety/depression. In addition, maternal separation has been shown to exacerbate the behavioural deficits induced by 6-hydroxydopamine (6-OHDA) in a rat model of Parkinson's disease. In ...
Takada Shingo - - 2012
Skeletal muscle bulk and strength are becoming important therapeutic targets in medicine. To increase muscle mass, however, intensive, long-term mechanical stress must be applied to the muscles, and such stress is often accompanied by orthopedic and cardiovascular problems. We examined the effects of circulatory occlusion in resistance training combined with ...
Desplan M - - 2012
AIM: To assess whether the severity of obstructive sleep apnoea syndrome (OSAS) is associated with altered fat oxidation (FO) during physical exercise in men with type 2 diabetes (T2DM) and/or the metabolic syndrome (MetS). METHODS: A total of 105 consecutive overweight or/and T2DM male patients were hospitalized for metabolic check-ups ...
Kroepfl Julia M - - 2012
Abstract Objective: Circulating hematopoietic progenitor cells (CPCs) may be triggered by both physical exercise and/or normobaric hypoxia from the bone marrow. The aim of the study was to investigate the influence of physical exercise and normobaric hypoxia on CPC number and functionality in the peripheral blood as well as the ...
Lambiase Maya J - - 2012
Cardiovascular responses during exercise are matched to the increased metabolic demand, but this may not be the case during psychological stress. No studies to date have tested this hypothesis in youth. Fifty-four youth, ages 13-16 years completed two visits. Heart rate (HR), systolic blood pressure (SBP), and oxygen (O(2)) consumption ...
Ciampi Quirino - - 2012
AIMS: Dobutamine stress echocardiography (DSE) is widely used to evaluate myocardial contractile reserve in patients with heart failure (HF). The aim of the study was to assess the relationship between the tissue Doppler (TD) mitral annulus systolic velocity (Sm) change during DSE, contractile reserve, and aerobic exercise capacity in HF ...
Peart Daniel J - - 2012
The purpose of this study was to investigate the effects of pre-exercise alkalosis on the physiological stress response to high-intensity exercise. Seven physically active males (age 22 ± 3 years, height 1.82 ± 0.06 m, mass 81.3 ± 8.4 kg and peak power output 300 ± 22 W) performed a repeated sprint cycle exercise following a dose of 0.3 g kg(-1) body mass of ...
Greenwood Benjamin N BN Department of Integrative Physiology, University of Colorado-Boulder, CO 80309-0354, USA. - - 2012
Humans who exercise are less likely to suffer from stress-related mood disorders. Similarly, rats allowed voluntary access to running wheels have constrained corticosterone responses to mild stressors and are protected against several behavioral consequences of uncontrollable stress which resemble symptoms of human anxiety and depression, including exaggerated fear and deficits ...
Neves F J FJ Programa de Pós-Graduação em Ciências Cardiovasculares, Faculdade de Medicina, Universidade Federal Fluminense, Niterói, RJ, - - 2012
To determine the hemodynamic mechanisms responsible for the attenuated blood pressure response to mental stress after exercise, 26 healthy sedentary individuals (age 29 ± 8 years) underwent the Stroop color-word test before and 60 min after a bout of maximal dynamic exercise on a treadmill. A subgroup (N = 11) ...
Nikolaidis Michalis G - - 2012
The central aim of this review is to address the highly multidisciplinary topic of redox biology as related to exercise using an integrative and comparative approach rather than focusing on blood, skeletal muscle or humans. An attempt is also made to re-define 'oxidative stress' as well as to introduce the ...
Schinkel Arend F L - - 2012
AIMS: Exercise myocardial perfusion imaging (MPI) is widely used, but the long-term prognostic value of this test in patients with normal exercise electrocardiographic testing is not defined. METHODS AND RESULTS: A consecutive group of 650 patients (428 men, mean age: 56 ± 11 years) with known or suspected coronary artery ...
Kishi Takuya - - 2012
Exercise training normalizes sympathetic outflow in hypertension and chronic heart failure. The aim of this study was to determine whether the exercise training inhibits sympathetic nerve activity (SNA) via reduction of oxidative stress through blocked angiotensin II type 1 receptor (AT(1)R) in rostral ventrolateral medulla (RVLM). We divided stroke-prone spontaneously ...
Mahmoody Seeyed Ali Akbar - - 2012
The effect of aerobic training and Ferula gummosa supplementation (90 mg/kg) on apelinergic system and markers of cardiac stress in hypertensive rats were studied. Chronically administered l-NAME resulted in an increased level of angiotensin-converting enzyme (ACE), malondialdehyde (MDA), and high-sensitive C-reactive protein (hs-CRP), and also reduced the levels of apelin, ...
Partington Sara L - - 2012
Regadenoson during exercise stress test (ETT) can provide maximal hyperemia for myocardial perfusion imaging (MPI), along with exercise information. Our aim was to study the feasibility and safety of regadenoson injection at peak ETT for submaximal heart rate (HR) response. Consecutive patients who underwent SPECT MPI with standard Bruce ETT ...
Zagatina Angela - - 2012
BACKGROUND: Knowledge of alteration in coronary artery flow during physical activity provides important and valuable information about every patient. AIM: The aim of our study was (a) to identify the possibility of assessing coronary artery flow parameters using different ultrasound systems during the exercise test and (b) to compare these ...
Szivak Tunde K - - 2012
ABSTRACT: Commercial high intensity, short rest (HI/SR) protocols have been anecdotally postured to be extremely demanding. However, limited prior studies have demonstrated HI/SR protocols to produce hyper-reactions in metabolic and adrenal function; thus the purpose of this study was to evaluate physiological effects of an acute, high intensity (75% 1RM), ...
Sanchis-Gomar Fabian - - 2012
ABSTRACT: Physical exercise positively influences epigenetic mechanisms and improves health, several issues remain unclear concerning the links between physical exercise and epigenetics. There is growing concern about the negative influence of excessive and persistent physical exercise on health. How an individual physically adapts to the prevailing environmental conditions might influence ...
Dhoble Abhijeet - - 2012
BACKGROUND: There are no published data on the safety of cardiopulmonary exercise testing in patients with aortic stenosis. METHODS: In this retrospective descriptive study, we examined 347 consecutive patients with aortic stenosis who underwent cardiopulmonary exercise testing at a tertiary referral center. We recorded major events including death, nonfatal major ...
Sharma Kavita - - 2012
Exercise stress testing is the most commonly used noninvasive method to evaluate for coronary artery disease in men and women. Although emphasis has been placed on the diagnostic value of ST-segment depression, the exercise stress test provides other valuable diagnostic and prognostic data, beyond ST-segment depression. The value of these ...
Argulian Edgar - - 2012
Exercise echocardiography is an important and useful tool for the evaluation of symptoms and monitoring the response to therapy in patients with hypertrophic cardiomyopathy (HCM). A significant number of patients without resting left ventricular outflow tract gradients develop dynamic obstruction with exercise. Detection of an exercise-induced gradient provides a therapeutic ...
Banerjee A - - 2012
Background:  Exercise stress testing offers a non-invasive, less expensive way of risk stratification prior to coronary angiography, and a negative stress test may actually avoid angiography. However, previous meta-analyses have not included all exercise test modalities, or patients without known Coronary artery disease (CAD). Methods and Results:  We systematically reviewed ...
Chaudhry Kavita K Department of Medicine, Jawaharlal Nehru Medical College, Swangi (Meghe), - - 2012
To determine the prevalence of prehypertension in young females and its correlation to various parameters like body mass index (BMI), waist hip ratio (WHR), waist circumference (WC) and family history, and blood pressure (BP) response to exercise stress testing. One hundred and fifty apparently healthy females of age group 18-25-years ...
Hopkins M E - - 2012
The effects of regular exercise versus a single bout of exercise on cognition, anxiety, and mood were systematically examined in healthy, sedentary young adults who were genotyped to determine brain-derived neurotrophic factor (BDNF) allelic status (i.e., Val-Val or Val66Met polymorphism). Participants were evaluated on novel object recognition (NOR) memory and ...
Cho Min Soo - - 2012
The relationship between blood pressure (BP) response during exercise and future cardiovascular events remains unclear. We assessed the association between an increase in early systolic BP (SBP) during exercise tests and future cardiovascular events in patients with sustained hypertension (sHT). Between 2002 and 2005, we enrolled 300 patients newly diagnosed ...
Brunelli Andrea - - 2012
PURPOSE: Although several studies have shown that immune cells stimulated by in vitro stress are capable to produce neurotrophins (NTs), there is still no evidence whether physiological stress, such as exercise, can modulate the in vivo levels of brain-derived neurotrophic factor (BDNF) in peripheral blood mononuclear cells (PBMCs). METHODS: This ...
Scoppetta Fausto - - 2012
Physical exercise induces various stress responses and metabolic adaptations that have not yet been completely elucidated. Novel biomarkers are needed in sport veterinary medicine to monitor training levels and to detect subclinical conditions that can develop into exercise-related diseases. In this study, protein modifications in horse plasma induced by prolonged, ...
Aoki Kosuke - - 2012
ABSTRACT: BACKGROUND: Muscle contraction during short intervals of intense exercise causes oxidative stress, which can play a role in the development of overtraining symptoms, including increased fatigue, resulting in muscle microinjury or inflammation. Recently it has been said that hydrogen can function as antioxidant, so we investigated the effect of ...
Punn Rajesh - - 2012
BACKGROUND: Echocardiography has been used to determine ventricular function, segmental wall motion abnormality, and pulmonary artery pressure before and after peak exercise. No prior study has investigated systolic and diastolic function using echocardiography at various phases of exercise in children. The aim of this study was to determine the fractional ...
Farney Tyler M - - 2012
Exercise has been noted in some, but not all studies, to elicit an oxidative stress. The discrepancy in findings may be related to differences in exercise intensity across protocols, as well as differences in training status of participants. PURPOSE: We compared blood oxidative stress biomarkers in exercise-trained men following three ...
Kerasioti Efthalia - - 2012
Exercise has been associated with oxidative stress that is correlated with muscle fatigue and reduced exercise performance. The aim of this study was to examine the effects of a special cake (consisting of carbohydrate to whey protein 3.5:1) vs an isocaloric carbohydrate cake on biomarkers of oxidative stress in 9 ...
Périard J D - - 2012
This study investigated the effects of moderate dehydration (~2.5% body weight) on muscle strength and endurance using percutaneous electrical stimulation to quantify central and peripheral fatigue, and isolate the combined effects of exercise-heat stress and dehydration, vs. the effect of dehydration alone. Force production and voluntary activation were calculated in ...
Puente-Maestu Luis - - 2012
Rationale:Exercise triggers skeletal muscle oxidative stress in patients with chronic obstructive pulmonary disease (COPD). Objective:To study the specific site(s) of reactive oxygen species (ROS) production in mitochondria isolated from skeletal muscle of COPD patients and its relationship with local oxidative stress induced by exercise.Methods:Vastus lateralis (VL) biopsies were obtained in ...
Sahlén Anders - - 2012
Exercise can lead to release of biomarkers such as cardiac troponin T (cTnT) and N-terminal pro-brain natriuretic peptide (NT-proBNP), a poorly understood phenomenon proposed to especially occur with high-intensity exercise in less trained subjects. We hypothesised that haemodynamic perturbations during exercise are larger in athletes with cTnT release, and studied ...
Brodov Yafim - - 2012
The aim of this study was to assess the effect of attenuation correction (AC) on left ventricular (LV) volumes and LV transient ischemic dilatation (TID) during dual-isotope single-photon emission computer tomographic (SPECT) myocardial perfusion imaging (MPI). Ninety-six patients (mean age 58 ± 11 years, 15% women, 38 patients completed exercise ...
Bengalorkar G M - - 2012
Single-photon emission computerized tomography for myocardial perfusion imaging (MPI) is a non-invasive technique. MPI is performed by subjecting the patient to exercise or by using a pharmacological stress agent. Regadenoson is a selective A 2A adenosine receptor agonist used when MPI with exercise is contraindicated. It binds to the A ...
Lalanza Jaume F - - 2012
The benefits of long-term moderate exercise for health are widely accepted in humans, but few animal studies have been undertaken to characterize the effects of such activity on emotionality and responsiveness to stress. The present study describes the effects of long-term moderate forced treadmill training (36 weeks) on exploratory activity, ...
Wright Heather E - - 2012
Blood marker concentrations such as cortisol (COR) and interleukin (IL)-6 are commonly used to evaluate the physiological strain associated with work in the heat. It is unclear, however, if hot environments of an equivalent thermal stress, as defined by a similar wet bulb globe temperature (WBGT), result in similar response ...
Alipour M - - 2012
Oxidative stress forms the foundation for the induction of multiple cellular pathways which can lead to the complications of diabetes mellitus that the most debilitating ones are diseases of the nervous system. In this study, we evaluated whether treadmill running could alleviate oxidative stress and apoptosis rate in the hippocampus ...
Costin Alex - - 2012
Purpose: We sought to determine if an exercise programme of moderate aerobic intensity would decrease the heart-rate response to mental stress in teenagers with normal hearts.Methods: Mental stress testing (50 arithmetic problems) was performed in student volunteers before and after a 5-week period of rigorous aerobic exercise training of 2.5 ...
Di Franco Antonino - - 2012
ST-segment depression during exercise stress testing in asymptomatic subjects showing normal coronary arteries is considered a "false-positive" result. Coronary microvascular dysfunction, however, might be a possible cause of ST-segment depression in these cases. We assessed the coronary blood flow response to adenosine and to cold pressor test in the left ...
Gabriel Brendan - - 2012
Regular exercise can reduce the risk of cardiovascular disease. Although moderate intensity exercise can attenuate post-prandial triacylglycerol, high-intensity intermittent exercise might be a more effective method to improve health. We compared the effects of high-intensity intermittent exercise and 30 mins of brisk walking on postprandial triacylglycerol, soluble adhesion molecules and ...
Faёs Camille - - 2012
AIM: Alpha-thalassemia is known to reduce intra-erythrocyte HbS (sickle hemoglobin) concentration in sickle cell trait (SCT) subjects. Because HbS was shown to increase oxidative stress, the purpose of this study was to assess the effects of the coexistence of α-thalassemia and SCT on oxidative stress markers and nitric oxide (NO) ...
Philp Andrew - - 2012
The glycogen content of muscle determines not only our capacity for exercise but also the signaling events that occur in response to exercise. The result of the shift in signaling is that frequent training in a low-glycogen state results in improved fat oxidation during steady-state submaximal exercise. This review will ...
Casimiro-Lopes Gustavo - - 2012
Free radical production is increased in many disease states and during exercise, but in the latter the concurrent stimulation of the antioxidant defense system seems to protect the organism from excessive production of reactive oxygen species. Chronic exercise can exert negative effects on the activity of mitochondrial glycerol phosphate dehydrogenase ...
Sato Hiroki - - 2012
Decreased activity has been reported in both nocturnal and diurnal primates during the prolonged dry season in western Madagascar, and this has been interpreted as a reaction to the severe environment, with its food scarcity and/or thermal stress. Several day-active lemurs rest more as trees defoliate, although the reason for ...
Husley Caleb R - - 2012
The purpose of this study was to compare metabolic demand of a kettlebell (KB) swing routine to treadmill (TM) running at equivalent rating of perceived exertion (RPE). Thirteen subjects (11 M, 2 F, age = 21.4 ± 2.1 y, weight = 73.0 ± 9.2 kg) completed a 10-min KB swing ...
Demachi K - - 2012
To assess the effects of starting or stopping leg cooling on the thermoregulatory responses during exercise, 60 min of cycling exercise at 30% of maximal oxygen uptake was performed under 4 conditions using tube trouser perfused with water at 10°C; no leg cooling (NC), starting of leg cooling after 30 ...
Stoebner Richard - - 2012
Intense exercise requires a significant increase in cardiac output in order to meet the needs of the skeletal muscles for oxygenated blood. In order to improve cardiac performance, the autonomic nervous system increases sympathetic tone primarily through release of norepinephrine from postganglionic receptors to stimulate the β-adrenergic receptors of the ...
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