Search Results
Results 701 - 750 of 754
< 6 7 8 9 10 11 12 13 14 15 16 >
Fried T A - - 1986
Atrial natriuretic factor (ANF) is a peptide originally found to be present in extracts of mammalian atria that possess marked natriuretic and diuretic qualities. A number of mechanisms have been suggested to explain these properties. Recently, it has been suggested that ANF may enhance glomerular filtration. In this report, we ...
Wilson J X - - 1986
Cardiovascular responses (cardiac frequency, fH; mean arterial pressure, Pa; ischiatic arterial blood flow; Qi; ischiatic vascular resistance, Ri) to 1-norepinephrine (NE), acetylcholine (ACH), [Asp1, Val5]-angiotensin II (ANG II), and arginine vasotocin (AVT) were studied in conscious chickens (Gallus gallus) and Pekin ducks (Anas platyrhynchos). Age-dependent changes, in the cardiovascular variables ...
Sved A F - - 1986
High affinity glutamate uptake in the intermediate portion of the nucleus tractus solitarius (NTS) was not altered by prior removal of one nodose ganglion or by prior midline transection at the level of the NTS. In contrast, glutamate uptake in a tissue punch of the septal nucleus was significantly reduced ...
Olson K R - - 1986
Plasma clearance and tissue accumulation of 125I-angiotensin I, [Asp1, Ile5]ANG I, and [14C]sucrose, an inert volume reference, were measured after a bolus injection into the dorsal aorta of rainbow trout, Salmo gairdneri. Retention and metabolism of ANG I to angiotensin II (ANG II) and their constituent 1-4 peptide by the ...
Howes L G - - 1986
Plasma levels of norepinephrine (NE) and the NE metabolite 3,4-dihydroxyphenylethylene glycol (DHPG) were measured simultaneously following sympathetic activation induced by standing, cold pressor testing and bicycle exercise at progressively increasing workloads in normal volunteers. Free DHPG and NE levels both increased with sympathetic activation, but free NE levels were a ...
Stoddard S L - - 1986
Hypothalamic sites were selected which elicited flight (escape) behavior in the freely moving cat. Sympatho-adrenal (SA) activation was determined by measuring the levels of norepinephrine (NE) and epinephrine (E) in bilateral adrenolumbar and peripheral venous plasma following stimulation of these 29 hypothalamic sites in 18 anesthetized cats. Heart rate (HR) ...
Griffis C - - 1986
Endogenous opiate peptides are known to exert a depressant action on ventilation (VE), and their plasma levels have been shown to be elevated during a variety of exercise protocols. We investigated whether they might modulate the control of the hyperpnea of short-term constant-load (CLE) and incremental (IE) cycle-ergometer exercise. Four ...
Kraemer W J - - 1985
Proenkephalin peptide F immunoreactivity, epinephrine, and norepinephrine were measured in the plasma of endurance-trained and untrained male subjects riding on a bicycle ergometer at 28%, 54%, 83%, and 100% of maximum oxygen consumption (VO2). At rest the trained group had peptide F levels almost twice the level of the untrained ...
Kono T - - 1985
Biological activities of asn1-,val5-angiotensin II (Hypertensin, Ciba, Asn1-,Val5-ANG II), ile5-angiotensin II (human angiotensin II, Ile5-ANG II) and sar1-angiotensin II (Sar1-ANG II) were compared in man. In 7 normal men 5 pmol/kg X min each of Asn1-,Val5-ANG II, Ile5-ANG II and Sar1-ANG II was infused iv from 0900 h to 0930 ...
Stratton J R - - 1985
To determine whether a benzodiazepine central nervous system depressant, alprazolam, inhibits sympathetic discharge during exercise stress, 11 healthy men, aged 21 to 35 years, performed symptom-limited treadmill tests before and on the third day of drug therapy (0.5 mg 3 times daily). Plasma epinephrine and norepinephrine levels were measured at ...
Bardon T - - 1985
The effects of systemic infusion of neurotensin (NT) were studied in four dogs fitted with strain-gauge transducers implanted on the ascending and descending colon. The motility index of the colon was enhanced for the duration of the 20 min NT infusion (20 pmol X kg-1 X min-1). Such stimulation was ...
Louie J A - - 1985
We calculated the percent change in initial vascular resistance during open loop intra-arterial infusions of norepinephrine (NE) in 12 acutely denervated isolated canine brains and 5 acutely denervated perfused hindlimbs. The studies were repeated on seven chronically denervated brains devoid of perivascular sympathetic fibers. All tissues were free of residual ...
Gasic S - - 1985
In 10 patients suffering from cardiac neurosis changes in plasma norepinephrine (NE) and epinephrine (E) were studied by an upright bicycle exercise and during psychological stress. Psychometric tests were also performed. 6 healthy subjects served as a control group. At exercise, no relevant differences in blood pressure and heart rate ...
Young M A - - 1985
We correlated levels of circulating norepinephrine (NE) and epinephrine (Epi) induced by 1) infusions, 2) treadmill exercise, and 3) hemorrhage with left ventricular (LV) function in conscious dogs instrumented for the measurement of LV and arterial pressures, LV diameter, and calculations of indexes of myocardial contractility. With infusions of NE, ...
Mena M A - - 1985
The influence of chronic stellectomy on external carotid flow responses to i.a. serotonin (5HT) was determined in dogs in which both stellate ganglia had been removed 1, 2, 4 or 8 weeks previously. The effect of this maneuver on carotid and heart rate responses to i.a. and i.v. norepinephrine (NE), ...
Pequignot J M - - 1985
Head-down bed rest at an angle of 6 degrees was used as an experimental model to simulate the hemodynamic effects of microgravity, i.e., the shift of fluids from the lower to the upper part of the body. The sympathoadrenal activity during acute (from 0.5 to 10 h) and prolonged (4 ...
Barron B A - - 1984
Retrogradely perfused bovine adrenal glands were stimulated by acetylcholine (ACh) and 1,1-dimethyl-4-phenyl-piperazinium (DMPP), with or without hexamethonium. Stimulation by either agent resulted in an increased release of both [Met5]enkephalin immunoreactive material (ME-IRM) and catecholamines as measured by radioimmunoassay and high performance liquid chromatography with electrochemical detection, respectively. ACh (5 X ...
Escourrou P - - 1984
To determine whether plasma catecholamine concentrations (a measure of sympathetic nervous activity [SNA]) rise above normoxic levels during exercise with hypoxemia, we exercised seven men for 15 min at three loads that required from 40 to 88% of maximal O2 uptake (VO2max). Subjects breathed room air on one day and ...
Musgrave I F - - 1984
In five males with mild essential hypertension, simultaneous hemodynamic and arterial and venous plasma catecholamine responses to three stimulation tests (mental arithmetic, isometric handgrip exercise, and cold) were studied. Plasma norepinephrine (NE), epinephrine (EPI), and dopamine (DA) were measured radioenzymatically. Isometric exercise was the best stimulus for systolic and diastolic ...
Zambraski E J - - 1984
Exercise is associated with an increase in plasma renin activity (PRA). The purpose of this study was to determine the role of the prostaglandin (PG) and adrenergic pathways in the renin release with exercise in the dog. One group of animals (n = 4) was exercised under control untreated and ...
Fagard R - - 1983
To evaluate the effect of dynamic exercise on the response to angiotensin II (AII), AII (7.5 ng/kg/min) or vehicle (P) was infused intravenously in seven normal sodium replete volunteers before, during and after a graded uninterrupted exercise test until exhaustion, using a randomized cross-over protocol. Plasma angiotensin II (PAII) during ...
Morioka S - - 1983
Systolic time measurements, echocardiography, and bicycle exercise testing with cardiac output determinations (CO2 rebreathing) were used to evaluate cardiac performance in 16 male hypertensives at the end of a 4-wk placebo period and after 12 wk of treatment with increasing doses (maximum = 40 mg/day) of enalapril maleate (N = ...
Fluharty S J - - 1983
Angiotensin and mineralocorticoids, the hormones of sodium conservation, acted together to arouse a sodium appetite with shorter latency and greater magnitude than is produced by larger amounts of each acting alone. This potentiation was selective for sodium ingestion and occurred in the absence of significant changes in sodium balance. Therefore, ...
Veith R C - - 1983
Fourteen depressed patients were treated for 1 to 8 wk (4.1 +/- 0.6, mean +/- SEM) with imipramine, doxepin, or amitriptyline to study the effects of tricyclic antidepressants (TCAs) on sympathetic nervous system (SNS) function. Eight had chronic but medically stable cardiac disease and six were medically healthy. Supine plasma ...
Bünger R - - 1983
The quantitative effects of norepinephrine (NE) on the active form of the cardiac pyruvate dehydrogenase complex (PDCa) and the rate of oxidative decarboxylation of pyruvate (MVPyr) were compared with those of pyruvate (Pyr). Isolated working guinea pig hearts metabolized pyruvate alone or in combination with alternative energy-providing substrates (ketone bodies, ...
Sowers J R - - 1983
This study examines the effects of age on plasma norepinephrine (NE) responses to upright posture and isometric handgrip exercise in nonobese men. Increasing age was associated with increased basal levels of plasma NE as well as increased NE responses to upright posture. These results suggest that aging affects sympathetic system ...
Ritter J M - - 1983
Concentrations of 6-oxo-prostaglandin F1 alpha (6-oxo-PGF1 alpha), the stable hydrolysis product of prostacyclin (PGI2) were determined in venous blood sampled from a forearm vein after dextrose (10% w/v) perfusion and after subsequent distension with physiological saline in seven healthy volunteers. 6-oxo-PGF1 alpha was measured by gas chromatography/negative ion chemical ionisation ...
Ylikorkala O - - 1983
To study the production of prostacyclin (PGI2) and thromboxane A2 (TxA2) in endometriosis in vitro, samples of endometriotic tissue taken during operation from 6 women were superfused for 4.5 hours in 95% O2/5% CO2 at 37 degrees C, and the stable metabolites of PGI2 (=6-keto-PGF1 alpha), and TxA2 (=TxB2) were ...
Chernow B - - 1983
The effect of fenfluramine on sympathetic nervous system activity was determined in 12 normotensive, obese men. Supine plasma norepinephrine (NE) concentrations decreased (p less than 0.001) from pretherapy levels (298 +/- 39 pg/ml) after one (166 +/- 30 pg/ml) and four weeks (171 +/- 28 pg/ml) of fenfluramine (60 mg ...
Rapoport R M - - 1983
The purpose of this study was to investigate the effect of prior agonist-induced contraction of vascular smooth muscle on its subsequent responsiveness and maximum contractility. Repeated exposure of the rabbit ear artery to equieffective histamine (Hist) or KCl concentrations increased subsequent norepinephrine (NE) responsiveness and maximum contractility in comparison to ...
Mäurer W - - 1982
In 17 patients suffering from severe chronic aortic regurgitation (AR) (New York Heart Association functional class III), right atrial biopsies were taken during aortic valve replacement. In these samples, we determined the myocardial content of norepinephrine (NE), normetanephrine (NM), epinephrine (E) and dopamine (DA). Two to 4 days before valve ...
Bock J L - - 1982
Plasma concentrations of the geometric isomers of 10-OH amitriptyline (10-OH AT) and 10-OH nortriptyline (10-OH-NT) were determined by reversed-phase high-pressure liquid chromatography. Steady-state concentrations of At, NT, and the four 10-OH metabolites were measured in 27 patients taking AT for depression. All of the unconjugated hydroxylated metabolites were usually detectable ...
Péronnet F - - 1981
Plasma norepinephrine (NE) concentration was measured by means of a sensitive radioenzymatic assay in blood collected from an antecubital vein in 10 healthy male subjects (37 +/- 2 yr, mean +/- SE). The subjects were evaluated at rest and during exercise before and after a 20-wk training program on bicycle ...
Wickler S J - - 1981
Nonshivering thermogenesis (NST) is a major contributor to total heat production capabilities of Peromyscus and the magnitude of the NST response increases dramatically in winter-acclimatized animals. To directly assess the contribution from skeletal muscle to this NST, a hindlimb perfusion system was developed for Peromyscus. Oxygen consumption was then measured ...
Hall J E - - 1981
Previous studies from our laboratory have provided evidence that the renin-angiotensin system plays an important role in controlling glomerular filtration rate (GFR) through an efferent arteriolar vasoconstrictor mechanism; however, the relative importance of circulating versus intrarenally formed angiotensin II (ANG II) in this control has not been determined. In the ...
Mehta S - - 1981
Contraceptive vaginal rings (CVRs) impregnated with a combination of estradiol and d-norgestrel were studied in 39 women. The rings were inserted as three weeks "in" and one week "out" schedule to allow withdrawal bleeding. Ovulation was inhibited in all cycles and promptly resumed on completion of the treatment cycles. Bleeding ...
Kim M Y - - 1981
THe alpha-adrenoreceptor-related dissociation constant and intrinsic efficacy of the stereoisomers of epinephrine were determined on the rabbit aortic strip. (-)-Epinephrine showed higher affinity than (+)-epinephrine or the desoxy analogue epinine. Efficacy of (+)-epinephrine relative to (-)-epinephrine was low (relative efficacy, er = 0.44). Epinephrine had about the same affinity and ...
Corrado M L - - 1980
Forty clinical isolates of Pseudomonas aeruginosa were tested for their susceptibility to cefoperazone, cefotaxime, moxalactam, piperacillin, N-formimidoyl thienamycin (MK0787), and gentamicin at three different inocula. At an inoculum of 5 x 10(3) colony-forming units (CFU) per ml, the minimum inhibitory concentrations (in micrograms per milliliter) for 90% of isolates (MIC90) ...
Hilsted J - - 1980
Peripheral plasma concentrations of gastroenteropancreatic peptides were measured during a 3-h period of bicycle exercise at 40% of maximal oxygen uptake in six normal men. Marked increases (P < 0.02) were found in vasoactive intestinal polypeptide (VIP) [1.8 +/- 0.7 (rest) vs. 22.3 +/- 5.4 pmol x l-1 (mean +/- ...
Lammintausta R - - 1980
In the clinical evaluation of renin status, the effect of chronic digitalization is unknown. A 50 per cent decrease in PRA is presented after intravenous digoxin injection. In this study the acute intake of 0.75 mg digoxin decreased PRA slightly (p less than 0,05), but no difference could be found ...
Hagberg J M - - 1979
Five subjects who had been training vigorously for 2 mo worked 5 min on the cycle ergometer at 1,480 +/- 100 kpm/min and at 1,920 kpm/min on separate days. Plasma norepinephrine (NE), blood lactate, and heart rate were determined during the postexercise periods. The same subjects were also tested at ...
Steiner R W - - 1979
Glomerular hemodynamics were measured by micropuncture technique in the plasma volume-expanded Munich-Wistar rat in 1) a control group, 2) during a pressor infusion of angiotensin II (AII), and 3) during simultaneous infusions of AII and saralasin, which returned arterial pressure to normal. Respective values obtained in the three groups studied ...
Pequignot J M - - 1979
The urinary excretion of dihydroxyphenylalanine (DOPA), catecholamines (CA) [dopamine (DA), norepinephrine (NE), and epinephrine (e)], their 3-O-methylated derivatives [3-O-methyldopamine (3-MT), normetanephrine (NMN), and metanephrine (MN)], and their deaminated metabolites [dihydroxyphenylacetic acid (DOPAC) and vanilmandelic acid (VMA)] was studied in six healthy men, at rest during short-term (15 min) or exhaustive ...
Muldoon S M - - 1979
A method for the measurement of norepinephrine (NE) overflow from isolated superfused canine saphenous veins is described. This method involves concentrating NE present in the superfusate, followed by measurement of its concentration by high-performance liquid chromatography with electrochemical detection. The limit of sensitivity of the method (defined as a signal-to-noise ...
Brandao F - - 1977
Canine isolated vein strips were labeled with tritiated norepinephrine (NE). Tritiated NE and its metabolites appearing during spontaneous outflow and during electric stimulation (10 Hz, 100 V, 2 msec, 5 minutes) were determined. The spontaneous outflow of tritiated compounds from the vein contained 90.5% metabolic products of NE, chiefly, the ...
Goldberg M R - - 1977
Contractile effects of prostaglandins (PGs) have not been widely studied in the canine saphenous vein, as in vitro model for venous function. We studied responses to two PG endoperoxide analogs (PGEA) and to monoenoic and bisenoic PGs of the A, B, E, and F series in helical strips of canine ...
Beil M - - 1977
Plasma nor-epinephrine (NE) and epinephrine (E) levels at rest and immediately after exercise were estimated in 8 patients with asymptomatic extrinsic allergic bronchial asthma. The patients had a normal airway resistance at rest and developed a marked bronchoconstriction (EIB) during exercise, which could be prevented by previous alpha-adrenergic blockade with ...
LeBlanc J - - 1977
Forty young male adults, aged 18-30 yr, with maximal oxygen intake (VO2 max) varying between 35 and 76 ml-kg-1-min-1 were studied. The fasting subjects were perfused for 15 min with saline and thereafter for 30 min with norepinephrine (0.1 mug/kg per min). Blood variables were determined at the end of ...
Assaf S Y - - 1976
Drinking elicited by administering angiotensin II (ANG II) to the preoptic region with cannulae passing through the lateral ventricles was attenuated significantly when the ventricles or subfornical organ were pretreated with saralasin acetate (Sar1-Ala8-angiotensin II). If the cannulae in the preoptice region were angled to bypass the lateral ventricles water ...
Miura Y - - 1976
Plasma catecholamine (CA) levels in the coronary sinus (CS), aorta (Ao) and femoral vein (fv) were simultaneously measured in 22 patients with various heart diseases at rest and during handgrip exercise (IHG). The mean resting levels of plasma norepinephine (NE) in CS, Ao and FV were 359 +/- 49 (SEM) ...
< 6 7 8 9 10 11 12 13 14 15 16 >