Search Results
Results 501 - 550 of 946
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Lavie Carl J - - 2007
Although under-emphasized, substantial evidence indicates that psychological distress, especially depression, hostility, and anxiety, are risk factors for coronary heart disease (CHD) and affect recovery following major coronary heart disease events. We review several major studies from Ochsner Medical Center demonstrating the high prevalence of psychological distress in CHD patients and ...
Baravelli Massimo - - 2007
BACKGROUND: Despite the great improvement in clinical management of patients with idiopathic dilated cardiomyopathy (DCM), sudden cardiac death (SCD) and death due to worsening heart failure (HF) remain a challenging problem. The assessment of oxygen consumption (peakVO(2)) has been recognized as an independent marker of mortality. Nevertheless peakVO(2) is not ...
Dutcher Jacob R - - 2007
This study evaluated exercise capacity and left ventricular ejection fraction (LVEF) as predictors of long-term mortality in patients with ST-elevation myocardial infarction (STEMI) treated with percutaneous coronary intervention. LVEF is a well-established predictor of mortality in patients with STEMI. Exercise capacity, expressed as milliliters per kilogram per minutes or METs ...
Ortega F B - - 2006
AIM: The relationship between extreme exercise and coronary artery disease is not well understood, and the information available is contradictory. The aim of the present study was to determine whether strenuous endurance exercise, performed under conditions in which the partial pressure of environmental oxygen varies constantly, can induce myocardial cell ...
Mohamed, Abdul Latiff
Our purpose is to report on the epidemiological variables and their association with the results of the exercise tolerance test (ETT) in the series of patients referred for standard diagnostic ETT at Seremban Hospital during the year 2001. ETT is widely performed, but, in Malaysia, an analysis of the associations ...
Choo Jina - - 2007
BACKGROUND: Health-related quality of life (HRQOL) has been used as a primary health outcome in cardiac rehabilitation programs (CRP). AIMS: This study aimed to evaluate the effects of an 8-week CRP on HRQOL and exercise capacity in myocardial infarction (MI) patients in Korea. METHODS: After matching on gender, age, and ...
Giallauria Francesco - - 2006
BACKGROUND: Heart rate recovery (HRR) is a marker of vagal tone that is a powerful predictor of mortality in patients with coronary artery disease. DESIGN: This study aims at evaluating the effects of long-term exercise training on HRR after acute myocardial infarction (AMI), in order to clarify whether prolonged exercise ...
Giallauria Francesco - - 2006
BACKGROUND: Heart rate recovery (HRR), defined as the fall in HR during the first minute after exercise, is a marker of vagal tone, which is a powerful predictor of mortality in patients with coronary artery disease and in older patients. Whether exercise training (ET) modifies HRR in elderly patients recovering ...
Petropoulou Evdokia - - 2006
OBJECTIVES: This study was performed to evaluate the feasibility of quantitative analysis of exercise echocardiography using pulsed wave Doppler myocardial imaging (DMI) and to examine the relation between age and DMI parameters at rest and during graded exercise in normal subjects. METHODS AND RESULTS: Seventy-two healthy volunteers were divided into ...
Wienbergen Harm - - 2006
BACKGROUND: Exercise testing has been advocated for risk stratification and determination of therapeutic strategies after acute myocardial infarction. Frequency and therapeutic impact of exercise testing after non-ST-elevation myocardial infarction (NSTEMI) in actual clinical practice, however, is not known. METHODS AND RESULTS: From the German acute coronary syndrome (ACOS) registry patients ...
Sanchis Juan - - 2006
We investigated whether the result of early exercise testing yields prognostic information in addition to that afforded by a clinical risk score in patients who present with chest pain in the emergency department. The study group consisted of 340 patients without preexisting evidence of myocardial ischemia. A clinical risk score ...
Delmez James A - - 2006
BACKGROUND: Cerebrovascular disease (CBVD) in hemodialysis patients is associated with significant morbidity and mortality. A secondary analysis of CBVD in the Hemodialysis (HEMO) Study was performed. Specific objectives were to: (1) determine risk factors for the presence of CBVD at baseline, (2) assess risk factors for the subsequent occurrence of ...
Iwanaga Yoshitaka - - 2005
BACKGROUND: The relationship of the genotype for the angiotensin-converting enzyme (ACE) with exercise capacity or training effects has been studied in athletes or healthy persons, but recently the ACE DD genotype was reported to be associated with decreased exercise capacity in patients with congestive heart failure. Therefore, in the present ...
Kato Kazuyo - - 2006
BACKGROUND: Recent studies indicated that excessive oxidative stress in an animal heart failure model injures both the sympathetic nerve endings and receptors, resulting in disturbance of norepinephrine release and sensitivity to norepinephrine. However, it has not been clarified whether this phenomenon is expressed clinically in patients with heart disease. Therefore, ...
Brown David A - - 2005
This study was conducted to examine the role of myocardial ATP-sensitive potassium (K(ATP)) channels in exercise-induced protection from ischaemia-reperfusion (I-R) injury. Female rats were either sedentary (Sed) or exercised for 12 weeks (Tr). Hearts were excised and underwent a 1-2 h regional I-R protocol. Prior to ischaemia, hearts were subjected ...
Motohiro Masayuki - - 2005
OBJECTIVE: This study examined the cardiovascular adaptations of an exercise training program and evaluated the role of peripheral vasodilator capacity in contributing to these adaptations after myocardial infarction. DESIGN: A total of 44 consecutive patients with uncomplicated myocardial infarction underwent 3 wks of exercise training. Controls (n = 12) with ...
Elhendy Abdou - - 2005
The aim of this study was to assess the relation between QRS duration and mortality in patients with known or suspected coronary artery disease, after adjustment for myocardial functional abnormalities, as assessed by exercise echocardiography. We studied 4,033 patients (age 62 +/- 12 years; 2,360 men, 18% with previous myocardial ...
Hesse Barbara - - 2005
OBJECTIVE: The aim of the study was to derive and externally validate a mortality prediction rule for patients undergoing exercise testing. BACKGROUND: The prognostic value of exercise testing is increasingly appreciated. However, global prognosis estimates ideally should account for numerous routinely obtained variables, including demographics, risk factors, resting electrocardiogram, and ...
Gehi Anil K - - 2005
OBJECTIVES: The objective of this study was to perform a meta-analysis of the predictive value of microvolt T-wave alternans (MTWA) testing for arrhythmic events in a wide variety of populations. BACKGROUND: Previous studies describing the use of MTWA as a predictor of ventricular tachyarrhythmic events have been limited by small ...
Gulati Martha - - 2005
Submaximal exercise testing is often used to estimate functional capacity in non-athletes, to assess cardiovascular disease in elderly or frail patients, to demonstrate exercise equipment, or to risk-stratify patients after myocardial infarction. However, submaximal exercise testing is not sufficiently sensitive, specific, or predictive to have widespread clinical utility, except in ...
McCully Robert B - - 2005
BACKGROUND: Patients with good exercise capacity and mildly abnormal exercise echocardiography results have a favorable overall prognosis. OBJECTIVE: We sought to define subgroups that might be at higher risk. METHODS: We examined outcomes of 868 patients (women, > or = 5 metabolic equivalents; men, > or = 7 metabolic equivalents) ...
Jouven Xavier - - 2005
BACKGROUND: Changes in heart rate during exercise and recovery from exercise are mediated by the balance between sympathetic and vagal activity. Since alterations in the neural control of cardiac function contribute to the risk of sudden death, we tested the hypothesis that among apparently healthy persons, sudden death is more ...
Izawa Kazuhiro P - - 2005
OBJECTIVE: To evaluate the effect of the self-monitoring approach (SMA) on self-efficacy for physical activity (SEPA), exercise maintenance, and objective physical activity level over a 6-mo period after a supervised 6-mo cardiac rehabilitation (CR) program. DESIGN: We conducted a randomized, controlled trial with 45 myocardial infarction patients (38 men, seven ...
Ueshima Kenji - - 2005
BACKGROUND: This study investigated the influence of exercise training on left ventricular (LV) function in patients with acute myocardial infarction (AMI) using a new index of cardiac function, the Tei index. METHODS AND RESULTS: The study enrolled 53 consecutive patients (36 males, 17 females; mean age: 65+/-10 years) with AMI. ...
Brown David A - - 2005
The cardioprotective effects of short-term exercise against myocardial ischaemia-reperfusion injury in male and female rats were examined. We subjected male and female rats to 0 (Sed; n = 8 males and 8 females), 1 (1 day; n = 10 males and 8 females), or 5 (5 day; n = 6 ...
Yoshinari Kazuyuki - - 2005
OBJECTIVE: The effects of exercise, a therapeutic tool in ischemic heart disease (IHD), may differ in ischemic and infarcted hearts. METHODS AND RESULTS: To assess this, we created coronary stenosis (CS), which reduced coronary flow reserve (CFR), or coronary occlusion to induce myocardial infarction (MI) in rats, and subjected them ...
Scognamiglio Roldano - - 2005
BACKGROUND: No data are available on the relationship between myocardial perfusion and left ventricular (LV) function in type 1 diabetes mellitus (T1DM), which may constitute a factor explaining the progressive contractile dysfunction to the overt phase of diabetic cardiomyopathy. HYPOTHESIS: This study was undertaken to test whether myocardial perfusion abnormalities ...
Desideri A - - 2005
To compare in a prospective, randomised, multicentre trial the relative merits of pre-discharge exercise ECG and early pharmacological stress echocardiography concerning risk stratification and costs of treating patients with uncomplicated acute myocardial infarction. 262 patients from six participating centres with a recent uncomplicated myocardial infarction were randomly assigned to early ...
Tayebjee Muzahir H - - 2005
BACKGROUND: Circulating metalloproteinases (MMP) and their inhibitors (TIMP) are indices of vascular and cardiac tissue matrix turnover. However, the temporal changes and relationship of these parameters to age, gender, ethnicity and exercise have been poorly defined. We therefore studied these aspects on plasma levels of MMP-2 and -9 and TIMP-1 ...
Jarrell Loretta A - - 2005
This study examined functional capacity and hemodynamic responses to exercise in men and women during early recovery after myocardial infarction (MI). Participants were tested at hospital discharge and six weeks following discharge. At each testing time, they completed the Beck Depression Inventory and a symptom-limited graded exercise test (SL-GXT). Functional ...
Elfatih A - - 2005
Nitric oxide (NO) plays a vital role in vascular homeostasis and in the pathophysiology of coronary heart disease. Its metabolites, nitrite and nitrate, have vasculoprotective properties, whereas peroxynitrite, an oxidant metabolite of NO, is cytotoxic and can aggravate myocardial damage during ischaemic reperfusion injury. Peroxynitrite nitrates free and protein bound ...
Erdogan Okan - - 2004
BACKGROUND: This study sought to determine whether adding an anti-histaminic medication, loratidine, to anti-ischemic treatment would ameliorate or improve ischemic parameters induced by exercise stress test in patients who suffered an acute myocardial infarction. METHODS: Twenty stable patients with acute inferior myocardial infarction who had a positive EST were randomly ...
Izawa Kazuhiro P - - 2004
OBJECTIVE: The purpose of this study was to determine exercise maintenance rate, leisure-time objective physical activity level, and health-related quality of life in relation to exercise maintenance over the 6-mo period after a supervised 5-mo recovery-phase cardiac rehabilitation program in acute myocardial infarction patients. The study also investigated whether exercise ...
Smith Lauren L - - 2005
Heart rate recovery after exercise, thought to be related to cardiac parasympathetic tone, has been shown to be a prognostic tool for all-cause mortality. However, the relationship between this variable and confirmed susceptibility to ventricular fibrillation (VF) has not been established. Therefore, myocardial ischemia was induced with a 2-min occlusion ...
Merkus Daphne - - 2005
Previous studies demonstrated a decreased flow reserve in the hypertrophied myocardium early after myocardial infarction (MI). Previously, we reported that exacerbation of hemodynamic abnormalities and neurohumoral activation during exercise caused slight impairment of myocardial O(2) supply in swine with a recent MI. We hypothesized that increased metabolic coronary vasodilation [via ...
Hamilton Karyn L - - 2004
Exercise provides protection against ischemia-reperfusion (I-R)-induced arrhythmias, myocardial stunning, and infarction. An exercise-induced increase in myocardial manganese superoxide dismutase (MnSOD) activity has been reported to be vital for protection against infarction. However, whether MnSOD is essential for exercise-induced protection against ventricular arrhythmias is unknown. We determined the effects of preventing ...
Castro R R T - - 2004
To determine the acute effects of pyridostigmine bromide, a reversible cholinesterase inhibitor, during exercise in patients with coronary artery disease. Double blind, randomised, placebo controlled, crossover study. Outpatients evaluated in an exercise test laboratory. 15 patients with exercise induced myocardial ischaemia. Maximal cardiopulmonary exercise test on a treadmill according to ...
Nasir Javed M JM Uniformed Services University of the Health Sciences, Bethesda, MD 20814, - - 2004
The Food and Drug Administration recently banned the sale of ephedra alkaloids because of their association with arrhythmic sudden death, myocardial infarction, and stroke. This has resulted in the emergence of formulations marketed for weight loss and performance enhancement that are "ephedra free" but contain other sympathomimetic substances, the safety ...
Morshedi-Meibodi Ali - - 2004
BACKGROUND: Recent investigations suggest that ventricular premature beats during exercise (EVPBs) are associated with increased cardiovascular mortality in asymptomatic individuals, but mechanisms underlying the association are unclear. METHOD AND RESULTS: We evaluated 2885 Framingham Offspring Study participants (1397 men; mean age, 43 years) who were free of cardiovascular disease and ...
Blumenthal James A - - 2004
PURPOSE: The large and well-characterized population of acute myocardial infarction (AMI) patients studied in the recently completed Enhancing Recovery in Coronary Heart Disease (ENRICHD) multicenter clinical trial provides a unique opportunity to examine the importance of self-reported regular physical exercise in a large cohort of patients with a recent AMI ...
Bigi Riccardo - - 2004
BACKGROUND: Exercise testing after acute myocardial infarction has limited prognostic accuracy. We prospectively used stress-recovery, heart rate-adjusted, ST-segment analysis to predict cardiac death in this clinical setting. METHODS: The stress-recovery index, defined as the difference in absolute values of the areas designated by ST depression in the heart-rate domain during ...
Yasuda Satoshi - - 2004
BACKGROUND: The hepatocyte growth factor (HGF) is a multifunctional cytokine with cardioprotective properties and potent myogenic activity for vascular endothelium. In patients after acute myocardial infarction, exercise training has the beneficial effects on cardiovascular adaptations. We hypothesized that exercise induces HGF production in those patients. If this hypothesis is correct, ...
Niemann T - - 2004
OBJECTIVE: To examine the association among different centres' referral practices for coronary angiography (CAG) after exercise testing, with 1- and 5-year outcomes. DESIGN: Observational population-based cohort study. SETTING: All 10 hospitals and six private practising consultants in Aarhus and Ringkjoebing counties (900 000 inhabitants), Denmark. SUBJECTS: All patients who in ...
Scoville Stephanie L - - 2004
BACKGROUND: A Recruit Mortality Registry, linked to the Department of Defense Medical Mortality Registry, was created to provide comprehensive medical surveillance data for deaths occurring during enlisted basic military training. METHODS: Recruit deaths from 1977 through 2001 were identified and confirmed through redundant sources. Complete demographic, circumstantial, and medical information ...
Lennon Shannon L - - 2004
Endurance exercise provides cardioprotection against ischemia-reperfusion-induced myocardial stunning and infarction. A recent study demonstrates that an exercise-induced increase in myocardial manganese superoxide dismutase (MnSOD) activity is essential to protect the heart against infarction. It is unknown if an elevation in cardiac MnSOD is also a prerequisite to achieve exercise-induced protection ...
Gaibazzi Nicola - - 2004
BACKGROUND: Previous work showed a strong inverse association between 1-min heart rate recovery (HRR) after exercising on a treadmill and all-cause mortality. The aim of this study was to determine whether the results could be replicated in a wide population of real-world exercise ECG candidates in our center, using a ...
Munih Marko - - 2004
The objective of the study was a quantitative examination of Proprioceptive Neuromuscular Facilitation (PNF) exercise in simultaneous combination with FES of lower extremity muscles in comparison to voluntary movement, training with PNF alone, or training with FES alone. Two subjects were monitored during a one-month rehabilitation period. The PNF pattern ...
Macrae Holden - - 2003
The objectives of this study were to assess whether exercise performance responses could be altered when subjects were exposed to interactive video feedback and music (VFM), compared to music only feedback (M). Ten women, 5 well-trained (46.4 ± 4.7 ml × kg(-1) × min(-1)) and 5 untrained (34.5 ± 5.7 ...
Elhendy Abdou - - 2003
OBJECTIVES: The goal of this research was to study the association between heart rate (HR) response to exercise and the risk of death and myocardial infarction (MI) after adjustment for left ventricular (LV) function and myocardial ischemia. BACKGROUND: Chronotropic incompetence during exercise testing is associated with increased mortality. It is ...
Peteiro Jesús - - 2003
Recommendations for risk assessment after acute myocardial infarction (AMI) include electrocardiographic (ECG) exercise testing. We hypothesized that a more sensitive technique, exercise echocardiography (EE), would refer a greater number of patients to invasive procedures. Therefore, we compared a strategy based on EE with a strategy based on ECG exercise testing ...
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