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Patki Gaurav G Department of Pharmacological and Pharmaceutical Sciences, University of Houston, TX, - - 2014
Social defeat (SD) induced stress causes physiological and behavioral deficits in rodents, including depression and anxiety-like behaviors, as well as memory impairment. Anxiolytic and mood elevating effects of physical exercise are also known. However, rescue effect of physical exercise in social defeat-induced anxiety, depression or memory impairment has not been ...
Puett Robin R Maryland Institute for Applied Environmental Health, University of Maryland, College Park, - - 2014
The importance of physical activity for health is well-established. Questions remain whether outdoor exercise additionally benefits overall mental and physical well-being. Using cross-sectional data from the Aerobics Center Longitudinal Study, we examined relationships of physical activity environment (PAE) with reported tension, stress, emotional outlook, and health. 11,649 participants were included. ...
Scott Adam C AC Department of Cardiology, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia; School of Public Health, Queensland University of Technology, Brisbane, Queensland, - - 2014
National guidelines for management of intermediate risk patients with suspected acute coronary syndrome, in whom AMI has been excluded, advocate provocative testing to final risk stratify these patients into low risk (negative testing) or high risk (positive testing suggestive of unstable angina). Adults less than 40 years have a low ...
Powers Christopher M CM Associate Professor and Co-Director, Jacquelin Perry Musculoskeletal Biomechanics Research Laboratory, Division of Biokinesiology and Physical Therapy, University of Southern California, Los Angeles, - - 2014
Study Design Single-group, repeated-measures design. Objective To compare patellofemoral joint (PFJ) stress among weight bearing and non-weight bearing quadriceps exercises. Background An important consideration in prescribing exercises to strengthen the quadriceps in persons with patellofemoral pain is to minimize PFJ loading. Currently there is disagreement in the literature as to ...
Goadsby Peter J PJ From the Headache Group, NIHR-Wellcome Trust Clinical Research Facility, King's College London, UK; and Department of Neurology, University of California, San - - 2014
This could be a statement about clinical practice, particularly completion of documentation; politics; modern life; or here, the pathophysiology of migraine. Only last year, Neurology® published a very challenging study demonstrating that alleged migraine triggers-flickering lights and strenuous exercise-were only about 10% likely to precipitate migraine in apparently susceptible individuals.(1) ...
Patki Gaurav G Department of Pharmacological and Pharmaceutical Sciences, University of Houston, Texas, - - 2014
Post-traumatic stress disorder (PTSD) is a condition which can develop from exposure to a severe traumatic event such as those occurring during wars or natural disasters. Benzodiazepines and selective serotonin reuptake inhibitors (SSRIs) are considered the gold standard for PTSD treatment, but their side effects pose a serious problem. While ...
Li Jia-Yi - - 2014
Involuntary exercising rats undergo more physical and mental stress than voluntary exercising rats; however these findings still lack electrophysiological evidence. Many studies have reported that theta rhythm appears when there is mental stress and that it is affected by emotional status. Thus, we hypothesized that the differences between voluntary and ...
Hong Heeok H Department of Medical Science, School of Medicine, Konkuk University, Seoul 143‑701, Republic of - - 2014
Immediate‑early genes are involved in acute stress responses in the central nervous system. β‑glucan stimulates innate immune defenses, exerts an anti‑tumor response and increases resistance to a wide variety of types of infection. To date, the effect of β‑glucan on the expression of immediate‑early genes under stressful conditions has not ...
Hochgruber Thomas T Department of Cardiology, University Hospital Basel, - - 2014
The impact of different forms of cardiac stress testing (exercise versus pharmacological stress testing) on cardiac wall stress and myocardial ischemia is incompletely understood. In a prospective study, 331 consecutive patients with suspected myocardial ischemia referred for nuclear perfusion imaging were enrolled: 266 underwent exercise (bicycle) stress testing and 65 ...
Sales Allan Robson Kluser AR Fluminense Federal - - 2014
Mental stress induces transient endothelial dysfunction, which is an important finding for subjects at cardiometabolic risk. Thus, we tested whether aerobic exercise prevents this dysfunction among subjects with metabolic syndrome (MetS) and whether an increase in shear rate (SR) during exercise plays a role in this phenomenon. Subjects with MetS ...
Hooper Philip L PL Division of Endocrinology, Metabolism and Diabetes, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA, - - 2014
Organisms have evolved to survive rigorous environments and are not prepared to thrive in a world of caloric excess and sedentary behavior. A realization that physical exercise (or lack of it) plays a pivotal role in both the pathogenesis and therapy of type 2 diabetes mellitus (t2DM) has led to ...
Lawson Eric C EC Department of Ophthalmology, Emory University School of Medicine, Atlanta, Georgia 30322, and Rehab R&D Center, Atlanta Veterans Administration Medical Center, Decatur, Georgia - - 2014
Aerobic exercise is a common intervention for rehabilitation of motor, and more recently, cognitive function (Intlekofer and Cotman, 2013; Wood et al., 2012). While the underlying mechanisms are complex, BDNF may mediate much of the beneficial effects of exercise to these neurons (Ploughman et al., 2007; Griffin et al., 2011; ...
Revilla Susana S Institut d'Investigacions Biomèdiques de Barcelona (IIBB), CSIC, IDIBAPS, Barcelona, - - 2014
Physical exercise has become a potentially beneficial therapy for reducing neurodegeneration symptoms in Alzheimer's disease. Previous studies have shown that cognitive deterioration, anxiety and the startle response observed in 7-month-old 3xTg-AD mice were ameliorated after 6 months of free access to a running wheel. Also, alterations in synaptic response to ...
Grégoire Catherine-Alexandra CA Department of Pathology and Cell Biology, Groupe de recherche sur le système nerveux central (GRSNC), and Center of Excellence in Neuroscience of the Université de Montréal (CENUM), Université de Montréal, Montréal, - - 2014
Environmental enrichment (EE) exerts powerful effects on brain physiology, and is widely used as an experimental and therapeutic tool. Typical EE paradigms are multifactorial, incorporating elements of physical exercise, environmental complexity, social interactions and stress, however the specific contributions of these variables have not been separable using conventional housing paradigms. ...
Wang Chong-Wen - - 2014
An increasing number of studies have documented the effectiveness of qigong exercise in helping people reduce psychological stress and anxiety, but there is a scarcity of systematic reviews evaluating evidence from randomized controlled trials (RCTs) conducted among healthy subjects. Thirteen databases were searched for RCTs from their inception through June ...
Russell Vivienne A VA Department of Human Biology, University of Cape Town, Observatory, 7925, South Africa, - - 2014
In response to acute adversity, emotional signals shift the body into a state that permits rapid detection, identification, and appropriate response to a potential threat. The stress response involves the release of a variety of substances, including neurotransmitters, neurotrophic factors, hormones, and cytokines, that enable the body to deal with ...
Stults-Kolehmainen Matthew A MA Yale School of Medicine, New Haven, - - 2014
Abstract Both cumulative adversity, an individual's lifetime exposure to stressors, and insufficient exercise are associated with poor health outcomes. The purpose of this study was to ascertain whether exercise buffers the association of cumulative adverse life events (CALE) with health in a community-wide sample of healthy adults (ages 18-50y; women: ...
Senan Mahavir M Yerevan State Medical University after M. Heratsi, Armenia; National Institute of Govt of India, Kolkata, - - 2014
During last years the relationship has been found in between sudden cardiac death and autonomic disbalance of nervous system, which effect on baroreflector regulation of heart rhythm. The importance of heart rate in cardiovascular prognosis can be explained by its relationship with major pathophysiological determinants. We considered this fact as ...
Tonello Laís L Department of Physical Education, Catholic University of Brasilia Brasilia, - - 2014
Physical activity (PA) and exercise are often used as tools to reduce stress and therefore the risk for developing cardiovascular diseases (CVD). Meanwhile, heart rate variability (HRV) has been utilized to assess both stress and PA or exercise influences. The objective of the present review was to examine the current ...
Cosín-Tomás Marta M Unitat de Farmacologia, Facultat de Farmàcia Institut de Biomedicina Universitat de Barcelona (IBUB), Nucli Universitari de Pedralbes Barcelona, Spain ; Department of Brain Ischemia and Neurodegeneration, Institut d'Investigacions Biomèdiques de Barcelona (IIBB)-Consejo Superior de Investigaciones Científicas (CSIC) Barcelona, - - 2014
The senescence-accelerated SAMP8 mouse model displays features of cognitive decline and Alzheimer's disease. With the purpose of identifying potential epigenetic markers involved in aging and neurodegeneration, here we analyzed the expression of 84 mature miRNAs, the expression of histone-acetylation regulatory genes and the global histone acetylation in the hippocampus of ...
Park Woncheoul W Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of - - 2014
Previous studies of horse RNA-seq were performed by mapping sequence reads to the reference genome during transcriptome analysis. However in this study, we focused on two main ideas. First, differentially expressed genes (DEGs) were identified by de novo-based analysis (DBA) in RNA-seq data from six Thoroughbreds before and after exercise, ...
Demarzo Marcelo M P MM Department of Preventive Medicine, "Mente Aberta" - Brazilian Center for Mindfulness and Health Promotion, Universidade Federal de São Paulo São Paulo, - - 2014
The psychological construct of mindfulness refers to an awareness that emerges by intentionally paying attention to the present experience in a non-judgmental or evaluative way. This particular quality of awareness has been associated to several indicators of physical and psychological health, and can be developed using mindfulness-based interventions (MBIs), and ...
Kobal Sergio L SL Cardiology Department, Soroka University Medical Center, Ben-Gurion University, Beer-Sheva, - - 2013
The prognostic value of ST-segment depression on exercise electrocardiogram (eECG) in the setting of a normal wall motion response in a stress echocardiographic study is not well defined. The aim of the study was to compare outcomes among patients with normal wall motion during stress echocardiography with and without ischemic ...
Stults-Kolehmainen Matthew A MA Department of Kinesiology and Health Education, The University of Texas at Austin Yale Stress Center, Yale School of - - 2013
The primary aim of this study was to determine whether chronic mental stress moderates recovery of muscular function and somatic sensations: perceived energy, fatigue and soreness, in a four-day period following a bout of strenuous resistance exercise. Undergraduate resistance training students (n = 31, age = 20.26 ± 1.34 y) ...
Castilla-Ortega Estela E Unidad de Gestión Clínica de Salud Mental, Hospital Regional Universitario Carlos Haya, Instituto de Investigación Biomédica de Málaga (IBIMA), Spain. Electronic address: - - 2013
We investigated whether voluntary exercise prevents the deleterious effects of chronic stress on episodic-like memory and adult hippocampal neurogenesis. After bromodeoxyuridine (BrdU) administration, mice were assigned to receive standard housing, chronic intermittent restraint stress, voluntary exercise or a combination of both (stress starting on the seventh day of exercise). Twenty-four ...
Neubauer Oliver - - 2013
Re-programming of gene expression is fundamental for skeletal muscle adaptations in response to endurance exercise. This study investigated the time-course dependent changes in the muscular transcriptome following an endurance exercise trial consisting of 1 h of intense cycling immediately followed by 1 h of intense running. Skeletal muscle samples were ...
Sanford Kate L - - 2013
Exercise stress testing is a non-invasive procedure that provides diagnostic and prognostic information for the evaluation of several pathologies, including arrhythmia provocation, assessment of exercise capacity, and coronary heart disease. Historically, exercise tests were directly supervised by physicians; however, cost-containment issues and time constraints on physicians have encouraged the use ...
Garcia-Alvarez Mercedes M Department of Anaesthesiology, Hospital de Sant Pau, Barcelona, Spain; Department of Intensive Care Medicine, Austin Hospital, Melbourne, - - 2014
An increased blood lactate concentration is common during physiological (exercise) and pathophysiological stress (stress hyperlactataemia). In disease states, there is overwhelming evidence that stress hyperlactataemia is a strong independent predictor of mortality. However, the source, biochemistry, and physiology of exercise-induced and disease-associated stress hyperlactataemia are controversial. The dominant paradigm suggests ...
Saleem Ayesha - - 2013
An acute bout of exercise activates downstream signaling cascades that ultimately result in mitochondrial biogenesis. In addition to inducing mitochondrial synthesis, exercise also triggers the removal of damaged cellular material via autophagy, and of dysfunctional mitochondria through mitophagy. Here we investigated the necessity of p53 for the changes that transpire ...
Russell Aaron P - - 2013
Maintaining skeletal muscle mitochondrial content and function is important for sustained health throughout the lifespan. Exercise stimulates important key stress signals that control skeletal mitochondrial biogenesis and function. Perturbations in mitochondrial content and function can directly or indirectly impact skeletal muscle function and consequently whole-body health and wellbeing. This review ...
Luo Beibei - - 2013
The purpose of this study was to examine the effect of moderate exercise on repeated restraint stress (RRS)-induced intestinal barrier dysfunction and explore possible mechanisms in a mouse model. Male Balb/c mice (6-week) were randomized into 7 groups: CON functioned as controls with no intervention; RRS was subjected to 6-hour ...
Hare Brendan D - - 2013
Exercise promotes stress resistance and is associated with reduced anxiety and reduced depression in both humans and in animal models. Despite the fact that dysfunction within the hypothalamic adrenal pituitary (HPA) axis is strongly linked to both anxiety and depressive disorders, the evidence is mixed as to how exercise alters ...
Toti L L Department of Traslational Research and New Technology in Medicine and Surgery, University of Pisa, Italy ; These authors contributed equally to this - - 2013
IN THE PRESENT STUDY WE INVESTIGATED THE EFFECT OF TWO DIFFERENT EXERCISE PROTOCOLS ON FIBRE COMPOSITION AND METABOLISM OF TWO SPECIFIC MUSCLES OF MICE: the quadriceps and the gastrocnemius. Mice were run daily on a motorized treadmill, at a velocity corresponding to 60% or 90% of the maximal running velocity. ...
Landers Merrill R - - 2013
Studies on exercise before and after toxin-induced hemiparkinsonism have reported promising findings in terms of amelioration of motor asymmetry in adult, 6-hydroxydopamine (6-OHDA) rats. However, recent studies have had more mixed results. Therefore, the purpose of this study was to further explore the notion of exercise, in particular forced exercise, ...
Wang Jing - - 2013
Exercise is beneficial to brain and can attenuate stress-induced hippocampal damages. However, the details involved monoamine neurotransmitter in exercise to counteract stress have not been well elucidated. The aim of this study was to examine exercise-induced responses of the norepinephrine (NE) and serotonin (5-HT) systems in counteracting stress-induced hippocampal damages. ...
Collimore Kelsey C - - 2013
There is accumulating evidence suggesting that anxiety sensitivity (AS) may play a role in social anxiety disorder (SAD; e.g., Ball, Otto, Pollack, Uccello, & Rosenbaum, 1995). Precedent research has demonstrated the role of AS in panic disorder and posttraumatic stress disorder, and subsequently, treatment techniques aimed at reducing AS (i.e., ...
Griesbach Grace Sophia - - 2013
We have recently shown that there is a heightened stress response after a mild traumatic brain injury (TBI) during the first two post-injury weeks. This corresponds to the same post-injury period when exercise does not increase brain derived neurotrophic factor (BDNF) and autonomic dysfunction becomes evident with exercise. Here we ...
Robinson Andrea M - - 2013
Exercising during pregnancy has been shown to improve spatial learning and short-term memory, as well as increase BDNF mRNA levels and hippocampal cell survival in juvenile offspring. However, it remains unknown if these effects endure into adulthood. In addition, few studies have considered how maternal exercise can impact cognitive functions ...
Kelly Scott - - 2013
Ventilatory control is affected by genetics, the environment, and gene-environment and gene-gene interactions. Here, we used an experimental evolution approach to test if 37 generations of selective breeding for high voluntary wheel running (genetic effects) and/or long-term (7-11 weeks) wheel access (training effects) alter acute respiratory behavior of mice resting ...
Yao Siu-Sun - - 2013
Submaximal stress testing or achieving <85% maximum predicted heart rate (MPHR) may lead to nondiagnostic results and indeterminate outcomes. High exercise capacity (≥10 metabolic equivalents, METS) is a predictor of favorable prognosis. The purpose of this study was to evaluate the prognostic value of submaximal or high exercise capacity stress ...
Thavendiranathan Paaladinesh - - 2013
To compare exercise stress cardiac magnetic resonance (cardiac MR) to echocardiography in healthy volunteers with respect to adequacy of endocardial visualization and confidence of stress study interpretation. Twenty-eight healthy volunteers (age 28 ± 11 years, 15 males) underwent exercise stress echo and cardiac MR one week apart assigned randomly to ...
Ferreira-Vieira Talita H - - 2013
It is well known that physical exercise has positive effects on cognitive functions and hippocampal plasticity. However, the underlying mechanisms have remained to be further investigated. Here we investigated the hypothesis that the memory-enhancement promoted by physical exercise relies on facilitation of the endocannabinoid system. We observed that the spatial ...
Deuster Patricia A - - 2013
Various groups representing a number of different perspectives (for example, operational, architectural, community, institutional, and individual resilience) use the term resilience. We define resilience as the ability to withstand, recover, and grow in the face of stressors and changing demands. Physical fitness is one pathway toward resilience because it is ...
Han Gun-Soo GS Department of Sports and Leisure Studies, College of Humanity, Daegu University, Republic of - - 2013
[Purpose] The purpose of this study was to investigate the effects of 8 weeks of endurance exercise on the cardiac mitochondrial function of mice. [Subjects] Ten 129 SvJ/C57BL6 Male mice were used. The mice were randomly divided into an exercise group (n=5; mean ± SD weight, 27.4 ± 1.6 g) and ...
Bridger Robert S - - 2013
Questionnaire data captured in January-March 2007 were examined in relation to turnover in males and females during the next five years. In general, most of the workplace stressors (such as role conflict or peer support) were not antecedents of turnover in any group. Junior personnel with psychological strain in 2007 ...
Castilla-Ortega Estela - - 2013
This work was aimed to assess whether voluntary exercise rescued behavioral and hippocampal alterations in mice lacking the lysophosphatidic acid LPA1 receptor (LPA1-null mice), studying the potential relationship between the amount of exercise performed and its effects. Normal and LPA1-null mice underwent 23 days of free wheel running and were ...
Harel Noam Y - - 2013
In the context of injury to the corticospinal tract (CST), brainstem-origin circuits may provide an alternative system of descending motor influence. However, subcortical circuits are largely under subconscious control. To improve volitional control over spared fibers after CST injury, we hypothesized that a combination of physical exercises simultaneously stimulating cortical ...
Wang Qin - - 2013
Exercise has been shown to enhance hippocampus-related cognition and slow the progression of Alzheimer's disease (AD). However, whether voluntary exercise directly decreases the neurotoxicity of amyloid peptide (Aβ) needs to be determined. In the present study, two-month old male C57bl/6 mice were intracerebroventricularly injected with Aβ25-35, and then allowed for ...
Stults-Kolehmainen Matthew A - - 2013
Psychological stress and physical activity (PA) are believed to be reciprocally related; however, most research examining the relationship between these constructs is devoted to the study of exercise and/or PA as an instrument to mitigate distress. The aim of this paper was to review the literature investigating the influence of ...
Nguyen Jason C D - - 2013
Exercise has been demonstrated to have positive effects on both the body and brain. The present study aimed to determine the behavioural and morphological consequence of low-intensity running. Rats were exercised on a treadmill for a total of 30days, 30min/day. Social interaction, locomotor activity and behaviour on an elevated plus ...
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