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Duvall W Lane - - 2013
BACKGROUND: Previous literature suggests that the results of myocardial perfusion imaging (MPI) add little to the prognosis of patients who exercise >10 metabolic equivalents (METS) during stress testing. With this in mind, we attempted to determine if a provisional injection protocol could be developed in which a patient would not ...
Benite-Ribeiro Sandra Aparecida - - 2013
Epidemiological studies have demonstrated that stress-related disorders, such as the increase on the caloric intake, are twice as common in women as in men, but surprisingly, very few studies have been tested this subject on female experimental animals. Additionally, it has been proposed that regular physical exercise can improve the ...
Sebire Simon J - - 2013
Goals are central to exercise motivation, although not all goals (e.g., health vs. appearance goals) are equally psychologically or behaviorally adaptive. Within goal content theory (Vansteenkiste, Niemiec, & Soenens, 2010), goals are adaptive to the extent to which they satisfy psychological needs for autonomy, competence, and relatedness. However, little is ...
Fang Zheng Huan - - 2013
A growing body of evidence suggests that exercise enhances hippocampal plasticity and function through BDNF up-regulation, which is potentiated by antidepressant treatment. However, little is known about the molecular mechanisms mediating the effect of exercise. The present study investigated the effect of treadmill exercise on PI3K/Akt signaling, which mediates synaptic ...
Uretsky Seth - - 2013
The obesity paradox has been reported in several populations of patients with cardiovascular disease. Recent data have shown that physical fitness may attenuate the obesity paradox. Patients who undergo pharmacologic stress testing are known to have a higher risk of mortality than those who can exercise. The purpose of this ...
Schoenfeld Timothy J TJ Department of Psychology, Neuroscience Institute, Princeton University, Princeton, New Jersey 08544, - - 2013
Physical exercise is known to reduce anxiety. The ventral hippocampus has been linked to anxiety regulation but the effects of running on this subregion of the hippocampus have been incompletely explored. Here, we investigated the effects of cold water stress on the hippocampus of sedentary and runner mice and found ...
Zielinski Mark R - - 2013
Sleep deprivation can have deleterious effects on cognitive function and mental health. Moderate exercise training has myriad beneficial effects on cognition and mental health. However, physiological and behavioral effects of chronic moderate sleep restriction and its interaction with common activities, such as moderate exercise training, have received little investigation. The ...
White Andrea T AT Department of Exercise & Sport Science, University of Utah, Salt Lake City, Utah 84112, USA. - - 2013
Heat stress is associated with increased fatigue perception and decrements in function for individuals with multiple sclerosis (MS). Similarly, healthy individuals experience decrements in exercise performance during hyperthermia. Alterations in central nervous system (CNS) function during hyperthermia include reduced voluntary activation of muscle and increased effort perception. The purpose of ...
Stoner Lee - - 2013
INTRODUCTION: Despite its potential, the validity of the flow-mediated dilation (FMD) test has been questioned because of lack of normalization to the vasodilatory stimulus. The hemodynamic conditions inside blood vessels lead to the development of superficial stress near the vessel walls, which can be divided into 2 categories: (1) circumferential ...
Landers Merrill R - - 2013
Several studies have found a neuroprotective effect of forced exercise in rodent Parkinson's disease models; however, the evidence for the protective effect of voluntary exercise is mixed. Most of these studies have initiated the exercise after toxin-induced hemiparkinsonism. Few studies have investigated the role of a preconditioning of exercise prior ...
Mairbäurl Heimo - - 2013
Introduction: Specific ATP release from red blood cells has been discussed as a possible mediator controlling microcirculation in states of decreased tissue oxygen. Since intravascular hemolysis might also contribute to plasma ATP, we tested in vitro, which portion of ATP release is due to hemolysis in typical exercise-induced strains to ...
Christianson John P - - 2013
Abstract Exposure to an uncontrollable stressor elicits a constellation of physiological and behavioral sequelae in laboratory rats that often reflect aspects of anxiety and other emotional disruptions. We review evidence suggesting that plasticity within the serotonergic dorsal raphe nucleus (DRN) is critical to the expression of uncontrollable stressor-induced anxiety. Specifically, ...
LaCroix Andrew S AS Department of Biomedical Engineering, University of Wisconsin-Madison, Madison, WI 53706, - - 2013
Tendon mechanical properties are thought to degrade during aging but improve with exercise. A remaining question is whether exercise in aged animals provides sufficient regenerative, systemic stimulus to restore younger mechanical behaviors. Herein we address that question with tail tendons from aged and exercised rats, which would be subject to ...
Radahmadi Maryam - - 2013
Different stressors induce learning and memory impairment and physical activity influence learning and memory enhancement. In this research, we investigated the effect of synchronized running activity with stress on acquisition and retention time of passive avoidance test. MALE WISTAR RATS WERE RANDOMLY DIVIDED INTO FIVE GROUPS AS FOLLOWS: Control (Co), ...
Seo Tae-Beom TB Department of Biochemistry, Division of Sports Science & Engineering, Korea Institute of Sports Science, Seoul, - - 2013
Autism is a complex neurodevelopmental disability with impairments of social interaction and communication, and repetitive behavior. Reelin is an extracellular glycoprotein that is essential for neuronal migration and brain development. Neuroprotective effects of exercise on various brain insults are well documented, however, the effects of exercise on autism in relation ...
Lee Hyeonkyeong H Department of Nursing Environments and Systems, Yonsei University, Seoul, South - - 2014
The purpose of this study was to assess the efficacy of a 12 week, self-managed, community-based stretching program on musculoskeletal fitness, musculoskeletal symptoms, and acculturative stress, in Korean-Chinese female migrant workers in Korea. This was a randomized controlled trial with random assignment of eligible full-time Korean-Chinese female migrant workers to ...
Kwon Dong-Ho - - 2013
We assessed whether chronic treadmill exercise attenuated restraint stress-induced cognition impairment. Although serum corticosterone was not significantly altered by exercise, the restraint-induced increases in hippocampal malondialdehyde (MDA) and 4-hydroxynonenal (HNE) were reduced by chronic exercise. The exercise paradigm also reversed stress-induced reductions in brain-derived neurotrophic factor (BDNF), which increased cAMP ...
Cairney John - - 2013
PURPOSE: To examine the prevalence of exercise as a coping behaviour for stress, compare this to other coping behaviours, and examine its demographic, behavioural, and health correlates in a nationally representative sample of Canadians. METHOD: We used data from the Canadian Community Health Survey 1.2, a cross-sectional survey of 36,984 ...
Gerecke Kim M - - 2013
Chronic stress induces high levels of reactive oxygen species, creating a neurotoxic environment. Because exercise protects against the neurodegenerative effects of oxidative stress, we investigated the protective effects of exercise against chronic restraint stress (CRS)-induced expression of the proapoptotic cortical B-cell associated X protein (Bax) and cyclooxegenase-2 (Cox-2) as well ...
Alomari Mahmoud A - - 2013
Multiple evidence suggest the importance of exercise for cognitive and brain functions. Few studies however, compared the behavioral and neural adaptations to force versus voluntary exercise training. Therefore, spatial learning and memory formation and brain-derived neurotrophic factor (BDNF) were examined in Wister male rats after 6 weeks of either daily ...
de Araujo Gustavo Gomes - - 2013
To assess the effects of continuous exercise training at intensities corresponding to 80 and 90 % of the lactate minimum test (LM), we evaluated antioxidant activity, hormone concentration, biochemical analyses and aerobic and anaerobic performance, as well as glycogen stores, during 12 weeks of swimming training in rats. One-hundred rats were separated ...
Richards Daniel A - - 2013
The loss of cardiac reserve is in part responsible for exercise intolerance in late stage heart failure (HF). Exercise tolerance testing (ETT) has been performed in mouse models of heart failure; however, treadmill performance and at-rest cardiac indices determined by magnetic resonance imaging (MRI) rarely correlate. The current study adopted ...
Lewis Evan J H - - 2013
The loss of muscle mass with age or sarcopenia contributes to increased morbidity and mortality. Thus, preventing muscle loss with age is important for maintaining health. Hsp72, the inducible member of the Hsp70 family, is known to provide protection to skeletal muscle and can be increased by exercise. However, ability ...
Legerlotz Kirsten - - 2013
Cyclic and static loading regimes are commonly used to study tenocyte metabolism in vitro and to improve our understanding of exercise associated tendon pathologies. The aims of our study were to investigate if cyclic and static stress relaxation affected the mechanical properties of tendon fascicles differently, if this effect was ...
Pastore Stephen F - - 2013
Circadian locomotor output cycles kaput (CLOCK) is a nuclear transcription factor which is a component of the central autoregulatory feedback loop that governs the generation of biological rhythms. Homozygous Clock mutant mice contain a truncated CLOCK(Δ19) protein within somatic cells, subsequently causing an impaired ability to rhythmically express circadian genes. ...
Nishijima Takeshi - - 2013
While increasing evidence demonstrates that physical exercise promotes brain health, little is known on how the reduction of physical activity affects brain function. We investigated whether the cessation of wheel running alters anxiety-like and depression-like behaviors and its impact on adult hippocampal neurogenesis in mice. Male C57BL/6 mice (4 weeks ...
de Souza Giovane Galdino - - 2013
BACKGROUND:Several studies have demonstrated antinociception induced by exercise; however, the specific mechanisms for this effect are not well understood. Thus, we investigated the involvement of α2-adrenergic receptors (α2-ARs) in the antinociceptive effect produced by exercise in rats and mice.METHODS:Male Wistar rats performed acute aerobic (AA) and acute resistance exercise protocols, ...
Griesbach Grace S GS Department of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, California 90095-7039, USA. - - 2013
We have previously reported that mild fluid percussion injury (FPI) is associated with a heightening of the hypothalamic-pituitary-adrenal axis response during the first post-injury weeks. This is the same time period when rehabilitative exercise has been strongly suggested to be ineffective. Here, we explored whether cardiac and temperature autonomic function ...
Brewer Britton W BW Department of Psychology, Springfield College, 263 Alden Street, Springfield, MA 01109, USA. - - 2013
Although home exercises are commonly prescribed following anterior cruciate ligament (ACL) reconstruction and are considered important in obtaining successful rehabilitation outcomes, little is known about factors associated with the completion of such exercises. Consequently, this study was designed to identify predictors of adherence to home rehabilitation exercises after ACL surgery. ...
Paine Nicola J - - 2013
Mental stress has been identified as a trigger of myocardial infarction (MI), with inflammation and vascular responses to mental stress independently implicated as contributing factors. This study examined whether inflammation moderates the vascular responses to mental stress. Eighteen healthy male participants completed a stress task under two counter balanced conditions. ...
Schoenfeld Brad J - - 2013
It is well established that regimented resistance training can promote increases in muscle hypertrophy. The prevailing body of research indicates that mechanical stress is the primary impetus for this adaptive response and studies show that mechanical stress alone can initiate anabolic signalling. Given the dominant role of mechanical stress in ...
Hosseini Nasrin - - 2013
Some studies have shown the effects of exercise training in retarding onset and progression of memory deficit in neurodegenerative disorders such as Alzheimer's disease. In this research, we investigated the effect of treadmill running on memory function; before, after, and continually (before and after) the nucleus basalis magnocellularis lesions. 66 ...
Lambiase Maya J - - 2013
BACKGROUND Studies in youth show an association between systolic blood pressure (SBP) reactivity to acute psychological stress and carotid artery intima-media thickness (CIMT). Submaximal exercise produces similar cardiovascular responses as acute psychological stress and may be a valuable tool to assess SBP reactivity in youth. However, it has not yet ...
Bernardi Caren - - 2013
Physical exercise effects on brain health and cognitive performance have been described. Synaptic remodeling in hippocampus induced by physical exercise has been described in animal models, but the underlying mechanisms remain poorly understood. Changes in astrocytes, the glial cells involved in synaptic remodeling, need more characterization. We investigated the effect ...
Rayhan Rakib U - - 2013
25% to 30% of Veterans deployed to the 1990 to 1991 Persian Gulf War exhibit an idiopathic syndrome of chronic fatigue, exertional exhaustion, pain, hyperalgesia, cognitive and affective dysfunction known as Gulf War Illness (GWI). Gulf War veterans (n=15) and sedentary veteran and civilian controls (n=11) completed a 2-back working ...
Matula Brian - - 2013
We all encounter various forms of stress every single day. Stress can be caused by family issues, relationships, children and especially work. With the ever-growing demands that are placed on Healthcare Security professionals today, career burnout associated with stress is becoming more and more common. In this article, the author ...
Srinivas Sunil Kumar - - 2013
A 56-year-old man with multiple risk factors undergoing evaluation for chest pain developed ST elevations in multiple leads during exercise stress test. These ST elevations were not classical of ischaemic pattern. The coronary angiogram showed normal coronaries. The false-positive ST elevation was due to an error in the computer-synthesised averaging ...
Javadi Hamid - - 2013
False-positive findings with myocardial perfusion imaging (MPI) have frequently been identified in the presence of left bundle branch block (LBBB) and tend to lower the accuracy of MPI in individuals with normal coronary angiographs. Pharmacologic stress is recognized as the preferred method for MPI in patients with LBBB. In contrast, ...
Ringholm Stine - - 2013
The aim of the present study was to test the hypotheses that 1) a single exercise bout increases UCP1 mRNA in both inguinal (i)WAT and epididymal (e)WAT, 2) UCP1 expression and responsiveness to exercise are different in iWAT and eWAT, 3) PGC-1α determines the basal levels of UCP1 and PRDM16 ...
Cotrim Carlos - - 2013
Exercise stress echocardiography is the most frequently used stress test in our laboratory. Exercise echocardiography is used mainly in the study of patients with coronary artery disease. However, the technique is increasingly being used to study other diseases.In our centre, we use an original methodology, published by us in 2000, ...
Maesako Masato - - 2013
High fat diet (HFD) is prevalent in many modern societies and HFD-induced metabolic condition is a growing concern worldwide. It has been previously reported that HFD clearly worsens cognitive function in amyloid precursor protein (APP) transgenic mice. On the other hand, we have demonstrated that voluntary exercise in an enriched ...
Shih Pei-Cheng - - 2013
Memory impairment is commonly noted in stroke survivors, and can lead to delay of functional recovery. Exercise has been proved to improve memory in adult healthy subjects. Such beneficial effects are often suggested to relate to hippocampal synaptic plasticity, which is important for memory processing. Previous evidence showed that in ...
Wang Zhuo - - 2013
Exercise training is widely used for neurorehabilitation of Parkinson's disease (PD). However, little is known about the functional reorganization of the injured brain after long-term aerobic exercise. We examined the effects of 4 weeks of forced running wheel exercise in a rat model of dopaminergic deafferentation (bilateral, dorsal striatal 6-hydroxydopamine ...
Nishijima Takeshi - - 2013
Physical exercise improves multiple aspects of hippocampal function. In line with the notion that neuronal activity is key to promoting neuronal functions, previous literature has consistently demonstrated that acute bouts of exercise evoke neuronal activation in the hippocampus. Repeated activating stimuli lead to an accumulation of the transcription factor ΔFosB, ...
Weng Tzu-Pin - - 2013
Exercise is linked with the type/intensity-dependent adaptive immune responses, whereas hypoxic stress facilitates the programmed death of CD4 lymphocytes. This study investigated how high intensity-interval (HIT) and moderate intensity-continuous (MCT) exercise training influence hypoxia-induced apoptosis and autophagy of CD4 lymphocytes in sedentary men. Thirty healthy sedentary males were randomized to ...
Santos-Soto Iván J IJ Department of Biology, University of Puerto Rico, Rio Piedras Campus, San Juan, Puerto - - 2013
Combinatorial therapies using voluntary exercise and diet supplementation with polyunsaturated fatty acids have synergistic effects benefiting brain function and behavior. Here, we assessed the effects of voluntary exercise on anxiety-like behavior and on total FA accumulation within three brain regions: cortex, hippocampus, and cerebellum of running versus sedentary young adult ...
Capomaccio Stefano S Department of Pathology, Diagnostic and Veterinary Clinic - Sport Horse Research Centre, University of Perugia, Perugia, - - 2013
The horse is an optimal model organism for studying the genomic response to exercise-induced stress, due to its natural aptitude for athletic performance and the relative homogeneity of its genetic and environmental backgrounds. Here, we applied RNA-sequencing analysis through the use of SOLiD technology in an experimental framework centered on ...
Ludlow Andrew T AT Department of Cell Biology, UT Southwestern Medical Center, Dallas, TX 75309, - - 2013
Aging is associated with a tissue degeneration phenotype marked by a loss of tissue regenerative capacity. Regenerative capacity is dictated by environmental and genetic factors that govern the balance between damage and repair. The age-associated changes in the ability of tissues to replace lost or damaged cells is partly the ...
Bengoetxea Harkaitz H Laboratory of Experimental Neuroscience, Department of Neuroscience, Faculty of Medicine and Odontology, University of the Basque Country Leioa, - - 2013
Elimination of sensory inputs (deprivation) modifies the properties of the sensory cortex and serves as a model for studying plasticity during postnatal development. Many studies on the effects of deprivation have been performed in the visual cortex using dark-rearing as a visual deprivation model. It induces changes in all cellular ...
Sasse Sarah K SK Department of Psychology and Neuroscience, University of Colorado Boulder, CO, - - 2013
Accumulating evidence indicates that regular physical exercise benefits health in part by counteracting some of the negative physiological impacts of stress. While some studies identified reductions in some measures of acute stress responses with prior exercise, limited data were available concerning effects on cardiovascular function, and reported effects on hypothalamic-pituitary-adrenocortical ...
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