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Sanford Kate L - - 2013
Exercise stress testing is a non-invasive procedure that provides diagnostic and prognostic information for the evaluation of several pathologies, including arrhythmia provocation, assessment of exercise capacity, and coronary heart disease. Historically, exercise tests were directly supervised by physicians; however, cost-containment issues and time constraints on physicians have encouraged the use ...
Garcia-Alvarez Mercedes M Department of Anaesthesiology, Hospital de Sant Pau, Barcelona, Spain; Department of Intensive Care Medicine, Austin Hospital, Melbourne, - - 2014
An increased blood lactate concentration is common during physiological (exercise) and pathophysiological stress (stress hyperlactataemia). In disease states, there is overwhelming evidence that stress hyperlactataemia is a strong independent predictor of mortality. However, the source, biochemistry, and physiology of exercise-induced and disease-associated stress hyperlactataemia are controversial. The dominant paradigm suggests ...
Saleem Ayesha - - 2013
An acute bout of exercise activates downstream signaling cascades that ultimately result in mitochondrial biogenesis. In addition to inducing mitochondrial synthesis, exercise also triggers the removal of damaged cellular material via autophagy, and of dysfunctional mitochondria through mitophagy. Here we investigated the necessity of p53 for the changes that transpire ...
Russell Aaron P - - 2013
Maintaining skeletal muscle mitochondrial content and function is important for sustained health throughout the lifespan. Exercise stimulates important key stress signals that control skeletal mitochondrial biogenesis and function. Perturbations in mitochondrial content and function can directly or indirectly impact skeletal muscle function and consequently whole-body health and wellbeing. This review ...
Luo Beibei - - 2013
The purpose of this study was to examine the effect of moderate exercise on repeated restraint stress (RRS)-induced intestinal barrier dysfunction and explore possible mechanisms in a mouse model. Male Balb/c mice (6-week) were randomized into 7 groups: CON functioned as controls with no intervention; RRS was subjected to 6-hour ...
Hare Brendan D - - 2013
Exercise promotes stress resistance and is associated with reduced anxiety and reduced depression in both humans and in animal models. Despite the fact that dysfunction within the hypothalamic adrenal pituitary (HPA) axis is strongly linked to both anxiety and depressive disorders, the evidence is mixed as to how exercise alters ...
Toti L L Department of Traslational Research and New Technology in Medicine and Surgery, University of Pisa, Italy ; These authors contributed equally to this - - 2013
IN THE PRESENT STUDY WE INVESTIGATED THE EFFECT OF TWO DIFFERENT EXERCISE PROTOCOLS ON FIBRE COMPOSITION AND METABOLISM OF TWO SPECIFIC MUSCLES OF MICE: the quadriceps and the gastrocnemius. Mice were run daily on a motorized treadmill, at a velocity corresponding to 60% or 90% of the maximal running velocity. ...
Landers Merrill R - - 2013
Studies on exercise before and after toxin-induced hemiparkinsonism have reported promising findings in terms of amelioration of motor asymmetry in adult, 6-hydroxydopamine (6-OHDA) rats. However, recent studies have had more mixed results. Therefore, the purpose of this study was to further explore the notion of exercise, in particular forced exercise, ...
Wang Jing - - 2013
Exercise is beneficial to brain and can attenuate stress-induced hippocampal damages. However, the details involved monoamine neurotransmitter in exercise to counteract stress have not been well elucidated. The aim of this study was to examine exercise-induced responses of the norepinephrine (NE) and serotonin (5-HT) systems in counteracting stress-induced hippocampal damages. ...
Collimore Kelsey C - - 2013
There is accumulating evidence suggesting that anxiety sensitivity (AS) may play a role in social anxiety disorder (SAD; e.g., Ball, Otto, Pollack, Uccello, & Rosenbaum, 1995). Precedent research has demonstrated the role of AS in panic disorder and posttraumatic stress disorder, and subsequently, treatment techniques aimed at reducing AS (i.e., ...
Griesbach Grace Sophia - - 2013
We have recently shown that there is a heightened stress response after a mild traumatic brain injury (TBI) during the first two post-injury weeks. This corresponds to the same post-injury period when exercise does not increase brain derived neurotrophic factor (BDNF) and autonomic dysfunction becomes evident with exercise. Here we ...
Robinson Andrea M - - 2013
Exercising during pregnancy has been shown to improve spatial learning and short-term memory, as well as increase BDNF mRNA levels and hippocampal cell survival in juvenile offspring. However, it remains unknown if these effects endure into adulthood. In addition, few studies have considered how maternal exercise can impact cognitive functions ...
Kelly Scott - - 2013
Ventilatory control is affected by genetics, the environment, and gene-environment and gene-gene interactions. Here, we used an experimental evolution approach to test if 37 generations of selective breeding for high voluntary wheel running (genetic effects) and/or long-term (7-11 weeks) wheel access (training effects) alter acute respiratory behavior of mice resting ...
Yao Siu-Sun - - 2013
Submaximal stress testing or achieving <85% maximum predicted heart rate (MPHR) may lead to nondiagnostic results and indeterminate outcomes. High exercise capacity (≥10 metabolic equivalents, METS) is a predictor of favorable prognosis. The purpose of this study was to evaluate the prognostic value of submaximal or high exercise capacity stress ...
Thavendiranathan Paaladinesh - - 2013
To compare exercise stress cardiac magnetic resonance (cardiac MR) to echocardiography in healthy volunteers with respect to adequacy of endocardial visualization and confidence of stress study interpretation. Twenty-eight healthy volunteers (age 28 ± 11 years, 15 males) underwent exercise stress echo and cardiac MR one week apart assigned randomly to ...
Ferreira-Vieira Talita H - - 2013
It is well known that physical exercise has positive effects on cognitive functions and hippocampal plasticity. However, the underlying mechanisms have remained to be further investigated. Here we investigated the hypothesis that the memory-enhancement promoted by physical exercise relies on facilitation of the endocannabinoid system. We observed that the spatial ...
Deuster Patricia A - - 2013
Various groups representing a number of different perspectives (for example, operational, architectural, community, institutional, and individual resilience) use the term resilience. We define resilience as the ability to withstand, recover, and grow in the face of stressors and changing demands. Physical fitness is one pathway toward resilience because it is ...
Han Gun-Soo GS Department of Sports and Leisure Studies, College of Humanity, Daegu University, Republic of - - 2013
[Purpose] The purpose of this study was to investigate the effects of 8 weeks of endurance exercise on the cardiac mitochondrial function of mice. [Subjects] Ten 129 SvJ/C57BL6 Male mice were used. The mice were randomly divided into an exercise group (n=5; mean ± SD weight, 27.4 ± 1.6 g) and ...
Bridger Robert S - - 2013
Questionnaire data captured in January-March 2007 were examined in relation to turnover in males and females during the next five years. In general, most of the workplace stressors (such as role conflict or peer support) were not antecedents of turnover in any group. Junior personnel with psychological strain in 2007 ...
Castilla-Ortega Estela - - 2013
This work was aimed to assess whether voluntary exercise rescued behavioral and hippocampal alterations in mice lacking the lysophosphatidic acid LPA1 receptor (LPA1-null mice), studying the potential relationship between the amount of exercise performed and its effects. Normal and LPA1-null mice underwent 23 days of free wheel running and were ...
Harel Noam Y - - 2013
In the context of injury to the corticospinal tract (CST), brainstem-origin circuits may provide an alternative system of descending motor influence. However, subcortical circuits are largely under subconscious control. To improve volitional control over spared fibers after CST injury, we hypothesized that a combination of physical exercises simultaneously stimulating cortical ...
Wang Qin - - 2013
Exercise has been shown to enhance hippocampus-related cognition and slow the progression of Alzheimer's disease (AD). However, whether voluntary exercise directly decreases the neurotoxicity of amyloid peptide (Aβ) needs to be determined. In the present study, two-month old male C57bl/6 mice were intracerebroventricularly injected with Aβ25-35, and then allowed for ...
Stults-Kolehmainen Matthew A - - 2013
Psychological stress and physical activity (PA) are believed to be reciprocally related; however, most research examining the relationship between these constructs is devoted to the study of exercise and/or PA as an instrument to mitigate distress. The aim of this paper was to review the literature investigating the influence of ...
Nguyen Jason C D - - 2013
Exercise has been demonstrated to have positive effects on both the body and brain. The present study aimed to determine the behavioural and morphological consequence of low-intensity running. Rats were exercised on a treadmill for a total of 30days, 30min/day. Social interaction, locomotor activity and behaviour on an elevated plus ...
Nadel Jeffrey - - 2013
Exercise is a natural form of neurophysiologic stimulation that has known benefits for mental health, maintenance of cerebral function, and stress reduction. Exercise is known to induce an upregulation of brain-derived neurotrophic factor and this is thought to be involved in associated increases in neural plasticity. Protein synthesis is also ...
Tsuji Michio - - 2013
This study investigated whether wearing common white sportswear can reduce heat stress more than being semi-nude during exercise of different intensities performed under radiant heat and wind conditions, such as a hot summer day. After a 20-min rest period, eight male subjects performed three 20 min sessions of cycling exercise at ...
M Akhavan Maziar - - 2013
Objective(s): The effect of maternal voluntary exercise on hippocampal BDNF level in rat offspring was studied. In addition, the possible role of hippocampal BDNF receptors in maternal exercise induced enhancement of learning in the rat pups was investigated. Materials and Methods: Pregnant rats have been randomly assigned to sedentary control ...
Fennich Nada - - 2013
Stress echocardiography is a valuable tool for the noninvasive diagnosis of ischemic heart disease. Despite its widely use in the clinical practice, safety and side effects profile have never been evaluated in Moroccans.The aim: To assess the safety and tolerability of the two stress echo modalities in Moroccans. The study ...
Lee Joseph C - - 2013
Coronary artery disease (CAD) remains a major health concern and the leading cause of death in Australia. Effective assessment of patients for possible CAD is a common problem in general practice. Non-invasive tests such as myocardial perfusion scans (MPS), exercise stress tests (ESTs) and stress echocardiography (using exercise or dobutamine ...
Li Hongwei - - 2013
A substantial amount of evidence has shown that treadmill running enhances neurogenesis, improves cognitive function, and protects the brain against neurodegenerative disorders. However, treadmill running is a type of forced exercise that could increase the level of corticosterone, which subsequently down-regulates neurogenesis and impairs cognitive function. The purpose of this ...
Clark Matthew M - - 2013
High stress is a prevalent problem in the worksite. To reduce stress, improve productivity, reduce absenteeism, and lower healthcare costs, many companies offer exercise classes or stress management programmes. Although physical activity is an important component of stress management, few worksites have integrated physical activity into their comprehensive stress reduction ...
Fernandes Jansen - - 2013
The deleterious effects of paradoxical sleep deprivation (SD) on memory processes are well documented. Physical exercise improves many aspects of brain functions and induces neuroprotection. In the present study, we investigated the influence of 4 weeks of treadmill aerobic exercise on both long-term memory and the expression of synaptic proteins ...
Frinchi M - - 2013
The lack of dystrophin in mdx mice leads to cycles of muscle degeneration and regeneration processes. Various strategies have been proposed in order to reduce the muscle-wasting component of muscular dystrophy, including implementation of an exercise programme. The aim of this study was to examine how low-intensity endurance exercise affects ...
Luijnenburg Saskia E - - 2013
To evaluate the additional value of dobutamine stress testing in patients with repaired tetralogy of Fallot (TOF) by relating stress imaging parameters at baseline to relevant parameters of clinical condition and right ventricular (RV) size during a serial follow-up. We prospectively included 27 patients (14 ± 4 years at baseline), ...
Harte Christopher B - - 2013
The present investigation examined associations between intensities of exercise involvement and posttraumatic stress (PTS) symptom cluster severity (reexperiencing, avoidance/numbing, and hyperarousal). The sample was comprised of 108 adults (54.6% women; Mage = 23.9, SD = 10.22, range = 18-62), who endorsed exposure to a Diagnostic and Statistical Manual of Mental ...
Jezova Daniela - - 2013
The relationship between anxiety and neuroendocrine response to stress stimuli is still not fully understood. The aim of this study was to evaluate the contribution of acute increase in state anxiety to neuroendocrine activation under stress conditions. To do so, it was necessary to find a stress condition of the ...
Wanner Samuel Penna - - 2013
The mechanisms underlying physical exercise-induced hyperthermia may be species specific. Therefore, the present study aimed to investigate the effects of exercise intensity and ambient temperature on the core body temperature (T core) of running mice, which provide an important experimental model for advancing the understanding of thermal physiology. We evaluated ...
Khan Hira Mujeeb - - 2013
The objective of this paper is to assess the efficacy of deep breathing as a relaxation activity using a wearable stress monitor. For this purpose, we developed a protocol with different mentally stressful activities interleaved with regular sessions of deep breathing. We used three physiological sensors: a heart rate monitor, ...
Jacob M J - - 2013
We present three interesting and representative cases of exercise ECGs which were done as part of Stress Myocardial Perfusion study. Aim is to emphasize the point that the stress part of the test should be conducted by an expert in the field and recovery phase ECG records should be analyzed ...
Hettinga Florentina J FJ University Medical Center Groningen, University of Groningen, The Netherlands. - - 2013
Developments in assistive technology such as handcycling provide attractive possibilities to pursue a healthy lifestyle for patients with spinal cord injury. The objective of the study is to evaluate physical stress and strain of handcycling against training guidelines as defined by the American College of Sports Medicine (ACSM). Seven able-bodied ...
Haddad Monoem - - 2013
The aim of this study was to access the effects of the Hooper's index variations (i.e. self-ratings of fatigue, stress, delayed onset muscle soreness (DOMS), and sleep) on rating of perceived exertion during a 10min submaximal exercise training session (RPE-10min) and then check the stability and the internal consistency of ...
Røsjø Helge - - 2013
The classic chromogranin-secretogranin (granin) proteins are produced in the myocardium and throughout the neuroendocrine system, but while chromogranin (Cg) A and B levels are high in the adrenal medulla, secretogranin (Sg) II production is higher in the pituitary gland. Whether these differences may influence the response to physical activity is ...
Parker Sarah M - - 2013
When people are involved in outdoor activities, it is important to be able to assess a situation and make rational decisions. The goal of this study is to determine the effects of 90 minutes of light-intensity exercise in a hot environment on executive functioning capabilities of healthy individuals. In this ...
Moore Jonathan P - - 2013
PURPOSE: Individuals exposed to total sleep deprivation may experience an increased risk of impaired thermoregulation and physiological strain during prolonged physical activity in the heat. However, little is known of the impact of more relevant partial sleep deprivation (PSD). This randomized counterbalanced study investigated the effect of PSD on thermal ...
Bärtsch Peter - - 2013
A 45-year-old healthy man wishes to climb Mount Kilimanjaro (5895 m) in a 5-day period, starting at 1800 m. The results of a recent exercise stress test were normal; he runs 10 km 4 or 5 times per week and finished a marathon in less than 4 hours last year. ...
Kim Ji-Eun - - 2013
Autism is a neurological disorder that occurs during childhood and is characterized by impairments in social interaction and communication, as well as restricted and repetitive behaviors. Abnormalities of the cerebellum in autism include Purkinje cell loss and motor disturbance. In the present study, we evaluated the effect of treadmill exercise ...
Vissing Kristian - - 2013
The striated muscle activator of Rho signaling (STARS) pathway is suggested to provide a link between external stress responses and transcriptional regulation in muscle. However, the sensitivity of STARS signaling to different mechanical stress has not been investigated. In a comparative study, we examined the regulation of the STARS signaling ...
Duvall W Lane - - 2013
BACKGROUND: Previous literature suggests that the results of myocardial perfusion imaging (MPI) add little to the prognosis of patients who exercise >10 metabolic equivalents (METS) during stress testing. With this in mind, we attempted to determine if a provisional injection protocol could be developed in which a patient would not ...
Benite-Ribeiro Sandra Aparecida - - 2013
Epidemiological studies have demonstrated that stress-related disorders, such as the increase on the caloric intake, are twice as common in women as in men, but surprisingly, very few studies have been tested this subject on female experimental animals. Additionally, it has been proposed that regular physical exercise can improve the ...
Sebire Simon J - - 2013
Goals are central to exercise motivation, although not all goals (e.g., health vs. appearance goals) are equally psychologically or behaviorally adaptive. Within goal content theory (Vansteenkiste, Niemiec, & Soenens, 2010), goals are adaptive to the extent to which they satisfy psychological needs for autonomy, competence, and relatedness. However, little is ...
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