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Russell Vivienne A VA Department of Human Biology, University of Cape Town, Observatory, 7925, South Africa, - - 2014
In response to acute adversity, emotional signals shift the body into a state that permits rapid detection, identification, and appropriate response to a potential threat. The stress response involves the release of a variety of substances, including neurotransmitters, neurotrophic factors, hormones, and cytokines, that enable the body to deal with ...
Stults-Kolehmainen Matthew A MA Yale School of Medicine, New Haven, - - 2014
Abstract Both cumulative adversity, an individual's lifetime exposure to stressors, and insufficient exercise are associated with poor health outcomes. The purpose of this study was to ascertain whether exercise buffers the association of cumulative adverse life events (CALE) with health in a community-wide sample of healthy adults (ages 18-50y; women: ...
Senan Mahavir M Yerevan State Medical University after M. Heratsi, Armenia; National Institute of Govt of India, Kolkata, - - 2014
During last years the relationship has been found in between sudden cardiac death and autonomic disbalance of nervous system, which effect on baroreflector regulation of heart rhythm. The importance of heart rate in cardiovascular prognosis can be explained by its relationship with major pathophysiological determinants. We considered this fact as ...
Cosín-Tomás Marta M Unitat de Farmacologia, Facultat de Farmàcia Institut de Biomedicina Universitat de Barcelona (IBUB), Nucli Universitari de Pedralbes Barcelona, Spain ; Department of Brain Ischemia and Neurodegeneration, Institut d'Investigacions Biomèdiques de Barcelona (IIBB)-Consejo Superior de Investigaciones Científicas (CSIC) Barcelona, - - 2014
The senescence-accelerated SAMP8 mouse model displays features of cognitive decline and Alzheimer's disease. With the purpose of identifying potential epigenetic markers involved in aging and neurodegeneration, here we analyzed the expression of 84 mature miRNAs, the expression of histone-acetylation regulatory genes and the global histone acetylation in the hippocampus of ...
Park Woncheoul W Department of Agricultural Biotechnology and Research Institute for Agriculture and Life Sciences, Seoul National University, Seoul, Republic of - - 2014
Previous studies of horse RNA-seq were performed by mapping sequence reads to the reference genome during transcriptome analysis. However in this study, we focused on two main ideas. First, differentially expressed genes (DEGs) were identified by de novo-based analysis (DBA) in RNA-seq data from six Thoroughbreds before and after exercise, ...
Demarzo Marcelo M P MM Department of Preventive Medicine, "Mente Aberta" - Brazilian Center for Mindfulness and Health Promotion, Universidade Federal de São Paulo São Paulo, - - 2014
The psychological construct of mindfulness refers to an awareness that emerges by intentionally paying attention to the present experience in a non-judgmental or evaluative way. This particular quality of awareness has been associated to several indicators of physical and psychological health, and can be developed using mindfulness-based interventions (MBIs), and ...
Childs Emma E Human Behavioral Pharmacology Laboratory, Department of Psychiatry and Behavioral Neuroscience, The University of Chicago Chicago, IL, - - 2014
Physical activity has long been considered beneficial to health and regular exercise is purported to relieve stress. However empirical evidence demonstrating these effects is limited. In this study, we compared psychophysiological responses to an acute psychosocial stressor between individuals who did, or did not, report regular physical exercise. Healthy men ...
Wiederhold Brenda K BK Virtual Reality Medical Institute, Brussels, - - 2014
The INTERSTRESS project developed a completely new concept in the treatment of psychological stress: Interreality, a concept that combines cognitive behavioral therapy with a hybrid, closed-loop empowering experience bridging real and virtual worlds. This model provides the opportunity for individual citizens to become active participants in their own health and ...
Raymond Lawrence W LW Departments of Family Medicine, Carolinas HealthCare System, Charlotte, NC, USA. University of North Carolina at Chapel Hill, USA. - - 2014
U.S. guidance for examining hazmat workers recommends stress testing be considered when heat stress is expected. However, the most common stress test-Bruce protocol treadmill electrocardiography (BPTE) wearing gym clothes-creates little thermal stress. Objective. Evaluate a novel thermal stress treadmill walk (TSTW). Methods. Body temperatures and heart rates during BPTE in ...
Tonello Laís L Department of Physical Education, Catholic University of Brasilia Brasilia, - - 2014
Physical activity (PA) and exercise are often used as tools to reduce stress and therefore the risk for developing cardiovascular diseases (CVD). Meanwhile, heart rate variability (HRV) has been utilized to assess both stress and PA or exercise influences. The objective of the present review was to examine the current ...
James Morgan H MH Neurobiology of Addiction Laboratory, The Centre for Brain and Mental Health Research, School of Biomedical Sciences and Pharmacy, Hunter Medical Research Institute, University of Newcastle Newcastle, NSW, - - 2014
Early life stress (ELS) is a known antecedent for the development of mood disorders such as depression. Orexin neurons drive arousal and motivated behaviors in response to stress. We tested the hypothesis that ELS alters orexin system function and leads to an altered stress-induced behavioral phenotype in adulthood. We also ...
Holmes Philip V PV Neuroscience Program, Psychology Department, Biomedical and Health Sciences Institute, The University of Georgia , Athens, GA , - - 2014
Current concepts of the neurobiology of stress-related disorders, such as anxiety and depression emphasize disruptions in neural plasticity and neurotrophins. The potent trophic actions of exercise, therefore, represent not only an effective means for prevention and treatment of these disorders, they also afford the opportunity to employ exercise paradigms as ...
Kobal Sergio L SL Cardiology Department, Soroka University Medical Center, Ben-Gurion University, Beer-Sheva, - - 2013
The prognostic value of ST-segment depression on exercise electrocardiogram (eECG) in the setting of a normal wall motion response in a stress echocardiographic study is not well defined. The aim of the study was to compare outcomes among patients with normal wall motion during stress echocardiography with and without ischemic ...
Stults-Kolehmainen Matthew A MA Department of Kinesiology and Health Education, The University of Texas at Austin Yale Stress Center, Yale School of - - 2013
The primary aim of this study was to determine whether chronic mental stress moderates recovery of muscular function and somatic sensations: perceived energy, fatigue and soreness, in a four-day period following a bout of strenuous resistance exercise. Undergraduate resistance training students (n = 31, age = 20.26 ± 1.34 y) ...
Castilla-Ortega Estela E Unidad de Gestión Clínica de Salud Mental, Hospital Regional Universitario Carlos Haya, Instituto de Investigación Biomédica de Málaga (IBIMA), Spain. Electronic address: - - 2013
We investigated whether voluntary exercise prevents the deleterious effects of chronic stress on episodic-like memory and adult hippocampal neurogenesis. After bromodeoxyuridine (BrdU) administration, mice were assigned to receive standard housing, chronic intermittent restraint stress, voluntary exercise or a combination of both (stress starting on the seventh day of exercise). Twenty-four ...
Neubauer Oliver - - 2013
Re-programming of gene expression is fundamental for skeletal muscle adaptations in response to endurance exercise. This study investigated the time-course dependent changes in the muscular transcriptome following an endurance exercise trial consisting of 1 h of intense cycling immediately followed by 1 h of intense running. Skeletal muscle samples were ...
Sanford Kate L - - 2013
Exercise stress testing is a non-invasive procedure that provides diagnostic and prognostic information for the evaluation of several pathologies, including arrhythmia provocation, assessment of exercise capacity, and coronary heart disease. Historically, exercise tests were directly supervised by physicians; however, cost-containment issues and time constraints on physicians have encouraged the use ...
Garcia-Alvarez Mercedes M Department of Anaesthesiology, Hospital de Sant Pau, Barcelona, Spain; Department of Intensive Care Medicine, Austin Hospital, Melbourne, - - 2014
An increased blood lactate concentration is common during physiological (exercise) and pathophysiological stress (stress hyperlactataemia). In disease states, there is overwhelming evidence that stress hyperlactataemia is a strong independent predictor of mortality. However, the source, biochemistry, and physiology of exercise-induced and disease-associated stress hyperlactataemia are controversial. The dominant paradigm suggests ...
Saleem Ayesha - - 2013
An acute bout of exercise activates downstream signaling cascades that ultimately result in mitochondrial biogenesis. In addition to inducing mitochondrial synthesis, exercise also triggers the removal of damaged cellular material via autophagy, and of dysfunctional mitochondria through mitophagy. Here we investigated the necessity of p53 for the changes that transpire ...
Russell Aaron P - - 2013
Maintaining skeletal muscle mitochondrial content and function is important for sustained health throughout the lifespan. Exercise stimulates important key stress signals that control skeletal mitochondrial biogenesis and function. Perturbations in mitochondrial content and function can directly or indirectly impact skeletal muscle function and consequently whole-body health and wellbeing. This review ...
Luo Beibei - - 2013
The purpose of this study was to examine the effect of moderate exercise on repeated restraint stress (RRS)-induced intestinal barrier dysfunction and explore possible mechanisms in a mouse model. Male Balb/c mice (6-week) were randomized into 7 groups: CON functioned as controls with no intervention; RRS was subjected to 6-hour ...
Hare Brendan D - - 2013
Exercise promotes stress resistance and is associated with reduced anxiety and reduced depression in both humans and in animal models. Despite the fact that dysfunction within the hypothalamic adrenal pituitary (HPA) axis is strongly linked to both anxiety and depressive disorders, the evidence is mixed as to how exercise alters ...
Toti L L Department of Traslational Research and New Technology in Medicine and Surgery, University of Pisa, Italy ; These authors contributed equally to this - - 2013
IN THE PRESENT STUDY WE INVESTIGATED THE EFFECT OF TWO DIFFERENT EXERCISE PROTOCOLS ON FIBRE COMPOSITION AND METABOLISM OF TWO SPECIFIC MUSCLES OF MICE: the quadriceps and the gastrocnemius. Mice were run daily on a motorized treadmill, at a velocity corresponding to 60% or 90% of the maximal running velocity. ...
Landers Merrill R - - 2013
Studies on exercise before and after toxin-induced hemiparkinsonism have reported promising findings in terms of amelioration of motor asymmetry in adult, 6-hydroxydopamine (6-OHDA) rats. However, recent studies have had more mixed results. Therefore, the purpose of this study was to further explore the notion of exercise, in particular forced exercise, ...
Wang Jing - - 2013
Exercise is beneficial to brain and can attenuate stress-induced hippocampal damages. However, the details involved monoamine neurotransmitter in exercise to counteract stress have not been well elucidated. The aim of this study was to examine exercise-induced responses of the norepinephrine (NE) and serotonin (5-HT) systems in counteracting stress-induced hippocampal damages. ...
Collimore Kelsey C - - 2013
There is accumulating evidence suggesting that anxiety sensitivity (AS) may play a role in social anxiety disorder (SAD; e.g., Ball, Otto, Pollack, Uccello, & Rosenbaum, 1995). Precedent research has demonstrated the role of AS in panic disorder and posttraumatic stress disorder, and subsequently, treatment techniques aimed at reducing AS (i.e., ...
Griesbach Grace Sophia - - 2013
We have recently shown that there is a heightened stress response after a mild traumatic brain injury (TBI) during the first two post-injury weeks. This corresponds to the same post-injury period when exercise does not increase brain derived neurotrophic factor (BDNF) and autonomic dysfunction becomes evident with exercise. Here we ...
Robinson Andrea M - - 2013
Exercising during pregnancy has been shown to improve spatial learning and short-term memory, as well as increase BDNF mRNA levels and hippocampal cell survival in juvenile offspring. However, it remains unknown if these effects endure into adulthood. In addition, few studies have considered how maternal exercise can impact cognitive functions ...
Kelly Scott - - 2013
Ventilatory control is affected by genetics, the environment, and gene-environment and gene-gene interactions. Here, we used an experimental evolution approach to test if 37 generations of selective breeding for high voluntary wheel running (genetic effects) and/or long-term (7-11 weeks) wheel access (training effects) alter acute respiratory behavior of mice resting ...
Yao Siu-Sun - - 2013
Submaximal stress testing or achieving <85% maximum predicted heart rate (MPHR) may lead to nondiagnostic results and indeterminate outcomes. High exercise capacity (≥10 metabolic equivalents, METS) is a predictor of favorable prognosis. The purpose of this study was to evaluate the prognostic value of submaximal or high exercise capacity stress ...
Thavendiranathan Paaladinesh - - 2013
To compare exercise stress cardiac magnetic resonance (cardiac MR) to echocardiography in healthy volunteers with respect to adequacy of endocardial visualization and confidence of stress study interpretation. Twenty-eight healthy volunteers (age 28 ± 11 years, 15 males) underwent exercise stress echo and cardiac MR one week apart assigned randomly to ...
Ferreira-Vieira Talita H - - 2013
It is well known that physical exercise has positive effects on cognitive functions and hippocampal plasticity. However, the underlying mechanisms have remained to be further investigated. Here we investigated the hypothesis that the memory-enhancement promoted by physical exercise relies on facilitation of the endocannabinoid system. We observed that the spatial ...
Deuster Patricia A - - 2013
Various groups representing a number of different perspectives (for example, operational, architectural, community, institutional, and individual resilience) use the term resilience. We define resilience as the ability to withstand, recover, and grow in the face of stressors and changing demands. Physical fitness is one pathway toward resilience because it is ...
Han Gun-Soo GS Department of Sports and Leisure Studies, College of Humanity, Daegu University, Republic of - - 2013
[Purpose] The purpose of this study was to investigate the effects of 8 weeks of endurance exercise on the cardiac mitochondrial function of mice. [Subjects] Ten 129 SvJ/C57BL6 Male mice were used. The mice were randomly divided into an exercise group (n=5; mean ± SD weight, 27.4 ± 1.6 g) and ...
Bridger Robert S - - 2013
Questionnaire data captured in January-March 2007 were examined in relation to turnover in males and females during the next five years. In general, most of the workplace stressors (such as role conflict or peer support) were not antecedents of turnover in any group. Junior personnel with psychological strain in 2007 ...
Castilla-Ortega Estela - - 2013
This work was aimed to assess whether voluntary exercise rescued behavioral and hippocampal alterations in mice lacking the lysophosphatidic acid LPA1 receptor (LPA1-null mice), studying the potential relationship between the amount of exercise performed and its effects. Normal and LPA1-null mice underwent 23 days of free wheel running and were ...
Harel Noam Y - - 2013
In the context of injury to the corticospinal tract (CST), brainstem-origin circuits may provide an alternative system of descending motor influence. However, subcortical circuits are largely under subconscious control. To improve volitional control over spared fibers after CST injury, we hypothesized that a combination of physical exercises simultaneously stimulating cortical ...
Wang Qin - - 2013
Exercise has been shown to enhance hippocampus-related cognition and slow the progression of Alzheimer's disease (AD). However, whether voluntary exercise directly decreases the neurotoxicity of amyloid peptide (Aβ) needs to be determined. In the present study, two-month old male C57bl/6 mice were intracerebroventricularly injected with Aβ25-35, and then allowed for ...
Stults-Kolehmainen Matthew A - - 2013
Psychological stress and physical activity (PA) are believed to be reciprocally related; however, most research examining the relationship between these constructs is devoted to the study of exercise and/or PA as an instrument to mitigate distress. The aim of this paper was to review the literature investigating the influence of ...
Nguyen Jason C D - - 2013
Exercise has been demonstrated to have positive effects on both the body and brain. The present study aimed to determine the behavioural and morphological consequence of low-intensity running. Rats were exercised on a treadmill for a total of 30days, 30min/day. Social interaction, locomotor activity and behaviour on an elevated plus ...
Nadel Jeffrey - - 2013
Exercise is a natural form of neurophysiologic stimulation that has known benefits for mental health, maintenance of cerebral function, and stress reduction. Exercise is known to induce an upregulation of brain-derived neurotrophic factor and this is thought to be involved in associated increases in neural plasticity. Protein synthesis is also ...
Tsuji Michio - - 2013
This study investigated whether wearing common white sportswear can reduce heat stress more than being semi-nude during exercise of different intensities performed under radiant heat and wind conditions, such as a hot summer day. After a 20-min rest period, eight male subjects performed three 20 min sessions of cycling exercise at ...
M Akhavan Maziar M Skin Research Center, Laboratory of Protein and Enzyme, Shahid Beheshti University (M.C), Shohada-e Tajrish Hospital, Shahrdari St, Tehran, Iran ; Department of Pharmacology, School of Medicine, Semnan University of Medical Sciences, Semnan, - - 2013
The effect of maternal voluntary exercise on hippocampal BDNF level in rat offspring was studied. In addition, the possible role of hippocampal BDNF receptors in maternal exercise induced enhancement of learning in the rat pups was investigated. Pregnant rats have been randomly assigned to sedentary control or voluntary exercise groups. ...
Fennich Nada - - 2013
Stress echocardiography is a valuable tool for the noninvasive diagnosis of ischemic heart disease. Despite its widely use in the clinical practice, safety and side effects profile have never been evaluated in Moroccans.The aim: To assess the safety and tolerability of the two stress echo modalities in Moroccans. The study ...
Lee Joseph C - - 2013
Coronary artery disease (CAD) remains a major health concern and the leading cause of death in Australia. Effective assessment of patients for possible CAD is a common problem in general practice. Non-invasive tests such as myocardial perfusion scans (MPS), exercise stress tests (ESTs) and stress echocardiography (using exercise or dobutamine ...
Li Hongwei - - 2013
A substantial amount of evidence has shown that treadmill running enhances neurogenesis, improves cognitive function, and protects the brain against neurodegenerative disorders. However, treadmill running is a type of forced exercise that could increase the level of corticosterone, which subsequently down-regulates neurogenesis and impairs cognitive function. The purpose of this ...
Clark Matthew M - - 2013
High stress is a prevalent problem in the worksite. To reduce stress, improve productivity, reduce absenteeism, and lower healthcare costs, many companies offer exercise classes or stress management programmes. Although physical activity is an important component of stress management, few worksites have integrated physical activity into their comprehensive stress reduction ...
Fernandes Jansen - - 2013
The deleterious effects of paradoxical sleep deprivation (SD) on memory processes are well documented. Physical exercise improves many aspects of brain functions and induces neuroprotection. In the present study, we investigated the influence of 4 weeks of treadmill aerobic exercise on both long-term memory and the expression of synaptic proteins ...
Frinchi M - - 2013
The lack of dystrophin in mdx mice leads to cycles of muscle degeneration and regeneration processes. Various strategies have been proposed in order to reduce the muscle-wasting component of muscular dystrophy, including implementation of an exercise programme. The aim of this study was to examine how low-intensity endurance exercise affects ...
Luijnenburg Saskia E - - 2013
To evaluate the additional value of dobutamine stress testing in patients with repaired tetralogy of Fallot (TOF) by relating stress imaging parameters at baseline to relevant parameters of clinical condition and right ventricular (RV) size during a serial follow-up. We prospectively included 27 patients (14 ± 4 years at baseline), ...
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