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Nemet Dan - - 2010
Physical activity plays an important role in tissue anabolism, growth and development, but the mechanisms that link patterns of exercise with tissue anabolism are not completely understood. The effectiveness of physical training depends on the training load and on the individual ability to tolerate it, and an imbalance between the ...
Stuempfle Kristin J - - 2010
OBJECTIVE: Physical stress (exercise and/or environmental) activates the sympathetic-adrenal-medullary (SAM) and hypothalamic-pituitary-adrenocortical (HPA) axes. The combination of ultraendurance exercise in the cold presents a unique summated stress to the body. The purpose of this study was to assess the stress hormone response in runners, cyclists, and skiers participating in a ...
Cadore Eduardo L - - 2009
Although adaptations to water-based resistance exercise and conventional water-based exercise have been investigated, little is known regarding acute anabolic and catabolic hormonal responses to these 2 types of exercise. The purpose of this study was to investigate the acute responses of salivary testosterone and cortisol to 2 water-based exercise protocols ...
De Souza M J - - 2010
BACKGROUND: The identification of subtle menstrual cycle disturbances requires daily hormone assessments. In contrast, the identification of severe menstrual disturbances, such as amenorrhea and oligomenorrhea, can be established by clinical observation. The primary purpose of this study was to determine the frequency of subtle menstrual disturbances, defined as luteal phase ...
West Daniel W D - - 2010
The aim of our study was to determine whether resistance exercise-induced elevations in endogenous hormones enhance muscle strength and hypertrophy with training. Twelve healthy young men (21.8 +/- 1.2 yr, body mass index = 23.1 +/- 0.6 kg/m(2)) trained their elbow flexors independently for 15 wk on separate days and ...
Nemet Dan - - 2009
BACKGROUND: Exercise affects growth and development through a complex interaction between the endocrine, immune, and nervous systems. To date very little is known about how these systems respond to exercise in children or adolescents. Moreover, there are few studies that have examined growth factors, pro-inflammatory cytokines, and peripheral blood mononuclear ...
Oliver Stacy R - - 2010
In children, exercise modulates systemic anabolism, muscle growth, and overall physiological development through the growth hormone (GH)-insulin-like growth factor I (IGF-I) axis. GH secretion, at rest and during exercise, changes with age and maturational status and can be blunted by hyperlipidemia and obesity, with possible negative effects on physiological growth. ...
West Daniel W D - - 2009
We aimed to determine whether exercise-induced elevations in systemic concentration of testosterone, growth hormone (GH) and insulin-like growth factor-1 (IGF-1) enhanced post-exercise myofibrillar protein synthesis (MPS) and phosphorylation of signalling proteins important in regulating mRNA translation. Eight young men (20 +/- 1.1 years, BMI = 26 +/- 3.5 kg m(-2)) ...
Le Panse B??n??dicte - - 2009
The present study investigated whether short-term oral administration of glucocorticoid would modify performance and selected hormonal and metabolic parameters during submaximal exercise in healthy women. Nine recreational female athletes completed cycling trials at 70-75% VO(2) max until exhaustion after either placebo (Pla, gelatin) or oral prednisone (Cor, Cortancyl, 50 mg ...
Nemet Dan - - 2009
We evaluated the effect of cold ice-pack application following a brief sprint-interval training on the balance between anabolic mediators [growth hormone (GH), insulin-like growth factor-I (IGF-I), testosterone], catabolic markers (cortisol, IGFBP-1), and circulating pro [Interlukin-6 (IL-6) and IL-1beta]- and anti-inflammatory cytokines [IL-1 receptor antagonist (IL-1ra)]. Twelve males, elite junior handball ...
Eliakim Alon - - 2009
The effect of a single exercise as well as exercise training on the growth hormone (GH)-insulin-like growth factor (IGF-I) axis and inflammatory cytokines was studied mainly in adults participating in individualized endurance-type sports. The gender-specific effect of exercise on these systems in adolescents is unknown. Therefore, the purpose of this ...
Izquierdo Mikel - - 2009
This study examined the effects of heavy resistance training on physiological acute exercise-induced fatigue (5 x 10 RM leg press) changes after two loading protocols with the same relative intensity (%) (5 x 10 RM(Rel)) and the same absolute load (kg) (5 x 10 RM(Abs)) as in pretraining in men ...
McClean Conor M - - 2009
Individuals with impaired glucose tolerance (IGT) have a greater risk of developing diabetes and cardiovascular disease compared with those with normal glycemic control. The aim of this study was to examine the effects of acute aerobic exercise on glycemia, regional arterial stiffness, and oxidative stress in obese subjects with IGT. ...
Roberts Michael D - - 2009
This cross-sectional study examined aging and resistance exercise-related changes in intramuscular gene expression in younger (21.3 +/- 0.6 years, 84.8 +/- 6.0 kg, 26.6 +/- 2.1 kg x m(-2); n = 11) and older men (67.6 +/- 1.3 years, 88.7 +/- 4.8 kg, 28.6 +/- 1.4 kg x m(-2); n ...
Caruso John F - - 2009
INTRODUCTION: In-flight muscle mass and strength losses are likely exacerbated by low growth hormone (GH) concentrations. Factors associated with exercise may foretell resultant GH levels and thereby help blunt future mass and strength losses. METHODS: To assess the ability of variables to predict GH variance from resistive exercise done on ...
Bizzarri C - - 2009
Glucocorticoid over-treatment in children with congenital adrenal hyperplasia (CAH) may suppress GH secretion and growth. Aims of our study were: 1) to evaluate post-exercise GH response in patients affected by CAH due to 21-hydroxylase deficiency, in comparison with a group of healthy subjects; 2) to investigate the relationship between the ...
Widdowson W Matthew - - 2009
The growth hormone (GH)/ insulin-like growth factor-I (IGF-I) axis exerts short-and long-term metabolic effects that are potentially important during exercise. Exercise is a potent stimulus to GH release and there is some evidence that the acute increase in GH is important in regulating substrate metabolism post-exercise. Regular exercise also increases ...
Nindl Bradley C - - 2009
INTRODUCTION: This study hypothesized that insulin-like growth factor-binding protein (IGFBP), rather than insulin-like growth factor I (IGF-I) itself, would be more responsive to acute exercise stress in a dose-dependent fashion. METHODS: Eight men (24 +/- 5 yr, 87 +/- 9 kg, 182 +/- 6 cm, 21 +/- 5% body fat) ...
Goto Kazushige - - 2009
We examined hormonal responses to slow movement exercise involving concentric (CON) and eccentric (ECC) actions. Nine men performed knee extension exercises: (1) low-intensity exercise with slow CON contractions (5-1; 5 s for CON and 1 s for ECC); (2) low-intensity exercise with slow ECC contractions (1-5; 1 s for CON ...
Charmas MaƂgorzata - - 2009
The aim of this study is to estimate the metabolic and hormone response in middle-aged women to acute physical aerobic exercise accompanied by music, the so-called "aerobics." The experiment (single 60-minute aerobics session) included 11 women aged between 30 and 50. The following variables were determined in blood samples collected ...
Ojasto Timo - - 2009
This study monitored acute neuromuscular responses and growth hormone (GH) and blood lactate (La) concentrations in the eccentric-concentric (ECC-CON) hypertrophic protocol by using various dynamic accentuated external resistance (DAER) loads in the bench press exercise. Male subjects (age = 32 +/- 4 years; n = 11) performed 4 sets of ...
Rubeck K Z - - 2009
Background  Several but not all trials suggest that GH replacement in GH-deficient adults improves aerobic exercise capacity, whereas its effect on muscle strength is more dubious. However, a denominator of these studies is a low sample size. Objective  We systematically reviewed and analysed all randomized, double-blind, placebo-controlled trials on the ...
Irving Brian A - - 2009
Abdominal adiposity is associated with reduced spontaneous GH secretion, and an increased incidence of the metabolic syndrome, type 2 diabetes, and cardiovascular disease. Exercise training increases GH secretion, induces abdominal visceral fat loss, and has been shown to improve the cardiometabolic risk factor profile. However, little is known about the ...
Kamimori G H - - 2009
The hormonal and cardiovascular responses to atropine and low-intensity exercise were examined in 7 young men. Subjects completed 3 trials in a single blind crossover design. During the first trial (T1), subjects received 2.0 mg of atropine intramuscularly at rest. Subsequently in trial 2 (T2), subjects received a saline placebo ...
Garde A H - - 2009
OBJECTIVE: Salivary cortisol is widely used in occupational health research. However, many ordinary daily activities can influence the concentrations of cortisol and the interpretation of field studies. The aim of the present study was to evaluate the effect of lifestyle factors on salivary cortisol in everyday settings. MATERIAL AND METHODS: ...
Meckel Yoav - - 2009
Exercise training efficiency depends on the intensity, volume, duration, and frequency of training, as well as on the athlete's ability to tolerate it. Recent efforts to quantify the effects of aerobic exercise training on hormonal response have suggested that exercise leads to simultaneous changes of antagonistic mediators. The effects of ...
Shing Cecilia M - - 2009
Bovine colostrum (BC) is rich in immune, growth and antimicrobial factors, which promote tissue growth and the development of the digestive tract and immune function in neonatal calves. Although the value of BC to human adults is not well understood, supplementation with BC is becoming increasingly popular in trained athletes ...
Manshouri Mahnaz - - 2008
Obestatin is a 23-amino-acid peptide encoded by the same gene as ghrelin. Because there is a paucity of data concerning the effects of exercise on obestatin, this study investigated the effect of anaerobic exercise training-detraining on obestatin and growth hormone (GH) plasma levels. Ten young female volunteers participated. Blood was ...
Eliakim Alon - - 2008
The diagnosis of Growth Hormone (GH) deficiency in children with short stature is complex, and in certain cases, might be very difficult. Most of the provocative tests used to evaluate GH deficiency use pharmacological agents. The artificial nature of the pharmacological tests and the possibility that these tests might not ...
Arlettaz A - - 2009
In order to test the hypothesis that salbutamol would change substrate oxidation during submaximal exercise, eight recreationally trained men twice performed 1 h at 60% VO(2) peak after ingestion of placebo or 4 mg of salbutamol. Gas exchange was monitored and blood samples were collected during exercise for GH, ACTH, ...
Sakharov D A - - 2008
We developed a semiquantitative method for the analysis of main growth hormone isoforms. The use of immunoaffinity sorbents, two-dimensional electrophoresis, and immunoblotting allows detection of more than 90% circulating growth hormone. It was demonstrated that the proportion of growth hormone isoforms in human serum before and after strenuous exercise remained ...
Hackney A C - - 2008
An increasing number of investigative research studies point to participation in endurance exercise training as having significant detrimental effects upon reproductive hormonal profiles in men. Specifically, men chronically exposed to this type of exercise training exhibit persistently reduced basal (resting-state) free and total testosterone concentrations without concurrent LH elevations. Men ...
Aperghis Michael - - 2009
OBJECTIVE: Elevated growth hormone (GH) levels lead to increased circulating insulin-like growth factor-I (IGF-I), but the effects on localised muscle IGF-I splice variant expression is not known. The effects of rhGH administration, with or without an acute bout of high resistance exercise, were measured on serum IGF-I and on the ...
Choi Kyoung-Shin - - 2008
Recently developed strategies and conditions to provide rational control of inorganic crystal growth via electrodeposition are presented with a specific focus on the systematic tuning of crystal habit and the regulation of branching growth. Precise morphology control is critical to investigate the effect that a material's morphologies have on physical ...
Weltman Arthur - - 2008
Obesity attenuates spontaneous GH secretion and the GH response to exercise. Obese individuals often have low fitness levels, limiting their ability to complete a typical 30-min bout of continuous exercise. An alternative regimen in obese subjects may be shorter bouts of exercise interspersed throughout the day. The objective of the ...
Gondoni L A - - 2008
BACKGROUND: Prader-Willi syndrome (PWS) is associated with an inappropriate proportion of fat mass (FM) to non-FM compared to simple obesity. Altered body composition in PWS resembles that seen in subjects with GH deficiency, in which a reduction of lean body mass (LBM) is observed. The low LBM may contribute to ...
Groban Leanne L Department of Anesthesiology, Wake Forest University School of Medicine, Medical Center Blvd., Winston-Salem, NC 27157-1009, USA. - - 2008
Whether the lusitropic potential of short-term exercise in aged rats is linked to an augmentation in the growth hormone/insulin-like growth factor-1 (GH/IGF-1) axis and an alteration in the cardiac renin angiotensin system (RAS) is unknown. Old (28-month-old) male, Fischer 344xBrown Norway rats were randomized to 4 weeks of GH supplementation ...
Widdowson W Matthew - - 2008
GH replacement in GH-deficient adults exerts clear effects on body composition, but there is a lack of high-quality evidence concerning its functional effects, which are more clinically important. This metaanalysis was carried out to determine the effects of GH replacement on exercise performance. A Medline search and examination of reference ...
Calil C M - - 2008
The menstrual cycle has been pointed out as a factor influencing halitosis. However, this relationship has not yet been clarified. The aim of this study was to evaluate the influence of gender and the menstrual cycle on the production of volatile sulphur compounds (VSC) in women (n=14) across the menstrual ...
Cadore Eduardo - - 2008
The aim of present study was to examine the relationships between serum and salivary values of free testosterone, dehydroepiandrosterone, and cortisol before and after a session of resistance exercise. Twenty-eight healthy men (mean age 40 years, s = 4) participated in the present study. Serum and salivary samples were collected ...
Gilbert Kate L - - 2008
Exercise is a potent stimulus for growth hormone (GH) release, although aging appears to attenuate this response. The aim of this study was to investigate GH responses to different exercise stimuli in young and early middle-aged men. Eight men aged 18-25 y and 8 men aged 40-50 y completed 3 ...
Burke Darren G - - 2008
The purpose of this study was to compare changes in muscle insulin-like growth factor-I (IGF-I) content resulting from resistance-exercise training (RET) and creatine supplementation (CR). Male (n=24) and female (n=18) participants with minimal resistance-exercise-training experience (=1 year) who were participating in at least 30 min of structured physical activity (i.e., ...
Judelson Daniel A - - 2008
Hypohydration (decreased total body water) exacerbates the catabolic hormonal response to endurance exercise with unclear effects on anabolic hormones. Limited research exists that evaluates the effect of hypohydration on endocrine responses to resistance exercise; this work merits attention as the acute postexercise hormonal environment potently modulates resistance training adaptations. The ...
Hill E E - - 2008
This study examined the influence of exercise intensity upon the cortisol response of the hypothalamic-pituitary-adrenal (HPA) axis. Specifically, we examined exercise at intensities of 40, 60, and 80% maximal oxygen uptake (VO2max) in an attempt to determine the intensity necessary to provoke an increase in circulating cortisol. Twelve active moderately ...
Baume Norbert - - 2008
There is anecdotal evidence that athletes use the banned substance Synacthen because of its perceived benefit with its associated rise in cortisol. To test the performance-enhancing effects of Synacthen, eight trained cyclists completed two, 2-day exercise sessions separated by 7-10 days. On the first day of each 2-day exercise session, ...
Di Luigi Luigi - - 2008
CONTEXT: Physical exercise-related stress activates hypothalamus-pituitary-adrenal (HPA) axis; nitric oxide is one of the mediators of the HPA axis response to stress, and phosphodiesterase type 5 inhibitors influences nitric oxide-linked biological activities. OBJECTIVE: The objective of the study was to investigate whether a single oral long half-life phosphodiesterase type 5 ...
Hoffman J - - 2008
The effect of 30 days of beta-alanine supplementation (4.8 g per day) on resistance exercise performance and endocrine changes was examined in eight experienced resistance-trained men. An acute resistance exercise protocol consisting of 6 sets of 12 repetitions of the squat exercise at 70 % of one-repetition maximum (1-RM) with ...
Pomerants T - - 2008
AIM: The aim of this study was to investigate the response of N-terminal propeptide of type I procollagen, crosslinked telopeptide of type I collagen and the growth hormone/insulin-like growth factor-I axis to acute aerobic exercise in boys at different pubertal stages METHODS: The subjects were 60 healthy boys (group I ...
Consitt Leslie A LA Department of Exercise and Sport Science, University of North Carolina at Greensboro, Greensboro, NC 27858, USA. - - 2008
Growth hormone (GH) is a powerful stimulator of the Janus kinase 2 (JAK2)-signal transducer and activator of transcription 5 (STAT5) pathway. Acute exercise is a known stimulus for GH secretion. The purpose of this study was to determine the phosphorylation of the JAK2-STAT5 pathway in human skeletal muscle in response ...
Roelands Bart - - 2008
Combined inhibition of dopamine (DA)/norepinephrine (NE) reuptake improves exercise performance and increases core temperature in the heat. A recent study demonstrated that this effect may primarily be related to increased DA activity. NE reuptake inhibition (NERI), however, has received little attention in humans, certainly in the heat, where central fatigue ...
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