Search Results
Results 451 - 500 of 1202
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Kosmas E N - - 2004
It is known that, in stable asthmatics at rest, tidal expiratory flow limitation (EFL) and dynamic hyperinflation (DH) are seldom present. This study investigated whether stable asthmatics develop tidal EFL and DH during exercise with concurrent limitation of maximal exercise work rate (WRmax). A total of 20 asthmatics in a ...
Barreiro E - - 2004
Blunted perception of dyspnoea under resistive loading has been observed in patients with a history of near-fatal asthma (NFA). The perception of dyspnoea at rest and at the end point of various exercises was assessed in such patients. Respiratory function and exercise capacity (6-min walking distance, incremental cycloergometry and inspiratory ...
Backer Vibeke - - 2004
BACKGROUND: Knowledge of respiratory diseases in an arctic population with increasingly westernized lifestyles provides the opportunity to obtain new information in this field. OBJECTIVE: To investigate the influence of environment and lifestyle on the presence of respiratory symptoms in a genetically homogenous population sample living under widely differing conditions. METHODS: ...
Brown Sandra M - - 2004
PURPOSE: To investigate the effect of daily brimonidine tartrate 0.15% on the dark-adapted pupil diameter. DESIGN: Observational case series. METHOD: Ten normal volunteers administered brimonidine to their right eyes once daily. Four to six hours later, infrared pupil photographs were taken after dark adaptation. Measurements were performed at baseline; on ...
Hermansen Christian L - - 2004
Exercise-induced bronchospasm (EIB) is an often-undiagnosed but common problem affecting both recreational and elite athletes. Although exercise can trigger exacerbation of chronic asthma, EIB should not be confused with the chronic inflammatory disease. In this article, Drs Hermansen and Kirchner review the incidence, diagnosis, and treatment of EIB and explain ...
Chalupa David C - - 2004
Ambient air particles in the ultrafine size range (diameter < 100 nm) may contribute to the health effects of particulate matter. However, there are few data on ultrafine particle deposition during spontaneous breathing, and none in people with asthma. Sixteen subjects with mild to moderate asthma were exposed for 2 ...
Anees W - - 2004
Serial peak expiratory flow records are recommended in the first-line investigation of suspected occupational asthma. The effects of sequentially reducing the numbers of working weeks, consecutive days at work and readings taken per day on diagnostic sensitivity and specificity were investigated, using good quality peak expiratory flow records from 81 ...
Cavalcanti Silvio - - 2004
BACKGROUND: Hemodialysis technique (dialysate composition, filter, convection/diffusion ratio, etc.) can have an impact on the patient's tendency to acute hypotension. We have examined the hypothesis that the dialysis technique affects the hypotension risk by altering the cardiovascular compensatory response to hemodialysis-induced hypovolemia. METHODS: Twelve hypotension-prone subjects were studied during six ...
Liangas G - - 2004
This study was conducted to assess the prevalence of laughter-induced asthma, and to study any associations with asthma-related triggers and measures of disease activity, using a questionnaire-based survey of asthma subjects in both the community and on presentation to hospital. A total of 105 subjects participated, and 44 (41.9%) reported ...
Tancredi G - - 2004
A simple exercise test would be useful for detecting exercise-induced asthma, a common problem in asthmatic children. The current study compared the 3-min step test with treadmill exercise for evaluating exercise-induced asthma in asthmatic children and assessed whether responses to both tests are influenced by baseline lung function and habitual ...
Pastva Amy - - 2004
Recent reports indicate that aerobic exercise improves the overall physical fitness and health of asthmatic patients. The specific exercise-induced improvements in the pathology of asthma and the mechanisms by which these improvements occur, however, are ill-defined; thus, the therapeutic potential of exercise in the treatment of asthma remains unappreciated. Using ...
Krivan Vlastimil - - 2004
Predator-prey models consider those prey that are free. They assume that once a prey is captured by a predator it leaves the system. A question arises whether in predator-prey population models the variable describing prey population shall consider only those prey which are free, or both free and handled prey ...
Bramon Elvira E Institute of Psychiatry, PO Box 63, De Crespigny Park, Denmark Hill, London SE5 8AF, UK. - - 2004
Mismatch negativity (MMN) is a measure of cortical activity that occurs in response to a change in auditory stimuli. We investigated whether MMN is a potential marker of genetic vulnerability to schizophrenia by comparing MMN in a group of patients with schizophrenia, their unaffected relatives, and controls. There are 25 ...
Bruno Michiko K - - 2004
Paroxysmal exercise-induced dystonia can occur with Parkinson's disease (PD), and in rare cases, this can also be the presenting symptom. We report on 2 second cousins (no known consanguinity) who presented with paroxysmal exercise-induced dystonia who later developed clinical features of PD. Although autosomal recessive inheritance was suggested, and the ...
Ragusa V Franco - - 2004
Aim of the study was to evaluate in a retrospective analysis the incidence and clinical characteristics of nonfatal systemic reactions (NSR) to subcutaneous immunotherapy over a 20-year period (1981-2000) and to compare two ten-year periods as regard to NSR rate and type as well as to identify risk factors for ...
Onadeko B O - - 2004
BACKGROUND: Exercise-induced asthma (EIA) is increasingly encountered among school children in Kuwait. Available evidence has shown that inflammatory mediators may be involved in the pathogenesis of EIA. Studies on release of inflammatory mediators have been carried out in adult patients with asthma in Kuwait, but no study on EIA involving ...
Emeryk Andrzej - - 2004
The aim of our study was to estimate the prevalence of asthma and some respiratory symptoms and diseases in schoolchildren from rural regions of Poland in 2001 and to compare these data with previous estimations in 1995. Repeated cross-sectional epidemiological studies were performed among 594 primary schoolchildren in 1995 and ...
Singer Mel - - 2004
The soldiers who perpetrated atrocities during the Vietnam War are a group much less studied than the victims of violence during peacetime. These soldiers were catalyzed by war to express a darker side of their humanity, a side that our society often chosses to ignore. At some level their experiences ...
Bozi Maria - - 2003
Paroxysmal exercise-induced dystonia (PED) is a rare, typically idiopathic familial condition, although sporadic and secondary cases have been reported. We present 2 cases where PED was the presenting feature of young-onset idiopathic Parkinson's disease (PD), preceding the onset of parkinsonian symptoms by 1.5 and 5 years, respectively. Initially, the dystonic ...
Brooks Edward G - - 2003
EIB is a common manifestation in diagnosed asthmatics and is a sensitive warning sign of worsening asthma. EIB may occur as an isolated entity in the absence of signs and symptoms of chronic asthma. Careful diagnosis is crucial in determining if this condition represents a preasthmatic state or simply a ...
Hallstrand Teal S TS Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington, Seattle, Washington 98195-6522, USA. - - 2003
The majority of individuals with asthma have mild disease, often in conjunction with allergic rhinitis and exercise-induced bronchoconstriction (EIB). Although health-related quality-of-life (HRQoL) is reduced in moderate to severe asthma and allergic rhinitis, little is known about the effect of mild asthma, mild allergic rhinitis, and EIB on HRQoL outcomes. ...
Seale J Paul - - 2003
1. Science, in the present paper, is defined as the systematic study of humans, based on deduction and inferences from reproducible observation and measurement. Physicianly practice is the art of healing through accurate diagnosis and treatment. 2. The science that is conducted by clinical pharmacologists involves both clinical studies, which ...
Sunyer J - - 2003
BACKGROUND: Eosinophils play a central role in asthma, but the interplay of the effects of smoking, eosinophils and asthma remains unclear. OBJECTIVE: The primary objective of our study was to investigate the extent to which smoking modifies the effect of asthma on circulating eosinophils, CD4+ and CD8+ T cell counts. ...
Tilles Stephen A - - 2003
Vocal cord dysfunction (VCD) is a nonorganic disorder of the larynx that involves unintentional paradoxical adduction of the vocal cords while breathing. The resultant symptoms can include dyspnea, chest tightness, cough, throat tightness, wheezing, or voice change. Most patients with VCD are female, and among adolescents and children, VCD tends ...
Rabe K F - - 2003
Despite concerns in the 1970s and 1980s about the safety of short-acting beta2-agonists, it is now generally accepted that these agents, used at appropriate doses, provide safe and effective treatment for asthma symptoms. After their introduction, beta2-agonists with a long duration of action--formoterol and salmeterol--became widely used as maintenance therapy ...
Mandell David L - - 2003
Exercise-induced laryngomalacia (EIL) is characterized by inspiratory stridor that is brought on by exercise (i.e. competitive sports) and fails to respond to treatment with bronchodilators (Smith et al., Ann Otol Rhinol Laryngol 1995;104:537-541). During exercise, (1) spirometric flow volume loops show evidence of variable extrathoracic obstruction, and (2) laryngoscopy shows ...
Storms William W - - 2003
PURPOSE: The purpose of this manuscript is to review the recent literature on exercise-induced asthma (EIA) and summarize the pathogenesis, diagnosis, and treatment of this condition. METHOD: A review of the English language medical literature was performed to obtain articles on EIA. RESULTS: The pathophysiology of EIA is not fully ...
Duncan Erica - - 2003
Studies of the acoustic startle response and of its inhibition by the presentation of a non-startling preliminary stimulus (prepulse inhibition, PPI) have revealed deficits in PPI in schizophrenic subjects compared to healthy controls. Animal studies indicate that atypical antipsychotics improve PPI deficits induced by NMDA antagonists more consistently than typical ...
Shankarkumar U - - 2003
HLA B27 association with seronegative spondarthritis (SSA) has been recognized for over a decade and its association with chronic synovitis in Haemophilia patients has been recently reported. We characterized the HLA B27 subtypes in a cohort of 98 B27 positive individuals with SSA (n = 45), haemophilia with chronic synovitis ...
Suh Sung-Suk - - 2003
Single-phase transition during flowering has been suggested by Hempel and Feldman (1994) [Planta 192: 276]. When early flowering ecotypes of Arabidopsis were microscopically observed, a long day signal simultaneously induced the acropetal (bottom to top) production of flower primordia and the basipetal (top to bottom) differentiation of paraclades (axillary flowering ...
Akcan Y - - 2003
Familial Mediterranean fever (FMF) is an autosomal recessive disorder characterized by recurrent fever of unknown origin, renal amyloidosis, peritonitis, pleuritis and/or synovitis. There have been many studies to elucidate the etiopathogenesis of FMF. IL-6 is a cytokine that can induce the formation of serum amyloid A and C-reactive protein, both ...
Gautrin D - - 2003
OBJECTIVE: The aim of this study was to explore the role of rhinoconjunctivitis (RC), taking into account atopy and the level of bronchial responsiveness to methacholine, on the incidence of respiratory symptoms and in the development and/or worsening of asthma. METHODS: We examined data from a prospective study in 769 ...
Fonseca-Guedes Cristina H F - - 2003
The response of asthmatic children to exercise has usually been evaluated by forced expiratory volume in 1 sec (FEV(1)). We reasoned that other respiratory indexes derived from the forced vital capacity maneuver such as forced expiratory flow between 25-75% of vital capacity (FEF(25-75%)) would add significant information in the evaluation ...
Pata Yavuz Selim YS Department of Otorhinolaryngology, Mersin, Turkey. - - 2003
We investigated the bactericidal activity of the cerumen in patients with recurrent otitis externa. Cerumen samples were collected from 2 groups. Group A (n = 20) consisted of patients with recurrent otitis externa (2 or more acute otitis externa attack in the current year) and group B (n = 30) ...
Fozard John R - - 2003
Mice rendered adenosine deaminase-deficient manifest an 'asthma' phenotype in the lungs that includes mast cell degranulation, eosinophilia, mucus hypersecretion and bronchial hyperresponsiveness. These changes can be reversed by enzyme therapy with adenosine deaminase, and attenuated by theophylline. Theophylline also blocks the pro-inflammatory effects of adenosine in allergen-challenged mice. Adenosine A(2A) ...
Tarlo Susan M - - 2003
OBJECTIVE: To describe the features of irritant-induced asthma and discuss the diagnosis in relation to differing workplace irritant exposures and symptomatic responses. DATA SOURCES: A review of MEDLINE articles on this topic from January 1, 1985, through December 31, 2001 was performed. STUDY SELECTION: The author selected relevant articles for ...
Stevens W J WJ Departement Immunologie, Allergologie en Reumatologie, Universiteit Antwerpen (UA), Universiteitsplein 1, B 2610 Antwerpen, België. - - 2003
The aim of this study was to evaluate the relative frequencies of sensitisation to four common inhalant allergens in two atopic populations suffering from asthma and/or rhinitis. One had been studied in the period of 1975 till 1979, and a second population was evaluated between 1992 and 1995. At both ...
Nieto L - - 2003
OBJECTIVES: To assess the utility of capsaicin test in the differential diagnosis of non-productive causes of chronic cough and to examine the effects of treatment on this reflex. PARTICIPANTS: 86 healthy volunteers and 101 patients with chronic cough: asthma (n: 54) gastroesophageal reflux (n: 35) and post-nasal drip syndrome (n: ...
Sudhir P - - 2003
To study the prevalence of exercise-induced bronchospasm (EIB), 400 schoolchildren, aged 7-15 years, 200 each from urban and rural areas were administered a standard respiratory questionnaire, spirometry and exercise challenge. The study documented a higher prevalence of EIB in urban areas compared with rural area, 13 vs. 10 per cent. ...
Ho Anthony M-H - - 2003
OBJECTIVE: To evaluate, by systematic review, the efficacy of heliox on respiratory mechanics and outcomes in patients with acute asthma. METHODS: The search strategy included searching electronic databases (MEDLINE, EMBASE, and The Cochrane Library) and the references of relevant articles. Study quality was assessed based on allocation concealment. Randomized controlled ...
Sinha Taru - - 2003
Exercise-induced bronchospasm is an obstruction of transient airflow that usually occurs five to 15 minutes after physical exertion. Although this condition is highly preventable, it is still underrecognized and affects aerobic fitness and quality of life. Diagnosis is based on the results of a detailed history, including assessment of asthma ...
Hong Jung-Ae - - 2003
Paeonia radix is the root of Paeonia japonica MIYABE, a perennial plant classified in the family Paeoniaceae. In the present study, the effects of Paeonia radix on performance in treadmill exercise, and 5-hydroxytryptamine (5-HT) synthesis and tryptophan hydroxylase (TPH) expression in the dorsal raphe were investigated. Time to exhaustion in ...
Lemanske Robert F RF - - 2003
The increasing incidence and prevalence of asthma in many parts of the world continue to make it a global health concern. The heterogeneous nature of the clinical manifestations and therapeutic responses of asthma in both adult and pediatric patients indicate that it may be more of a syndrome rather than ...
Lopiano Leonardo - - 2003
OBJECTIVE: Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is a very effective therapy for the advanced phase of Parkinson's disease (PD). The functional inhibition of this nucleus is responsible for a significant improvement of cardinal motor symptoms of PD. The aim of the study was the assessment of ...
Pinna Baingio - - 2003
The watercolor effect is perceived when a dark (e.g., purple) contour is flanked by a lighter chromatic contour (e.g., orange). Under these conditions, the lighter color will assimilate over the entire enclosed area. This filling-in determines figure-ground organization when it is pitted against the classical Gestalt factors of proximity, good ...
Kumar Parveen - - 2003
I have struggled with schizophrenia throughout my life. I present the case report of my life to demonstrate that the fundamental psychopathology that caused various symptoms of schizophrenia in me was that my prefrontal lobe had become inert and inactive. Once I reactivated my prefrontal lobe by various prefrontal lobe ...
Mickleborough Timothy - - 2003
Exercise-induced asthma (EIA) occurs in up to 90% of individuals with asthma and approximately 10% of the general population without asthma. EIA describes a condition in which vigorous physical activity triggers acute airway narrowing with heightened airway reactivity resulting in reductions in forced expiratory volume in 1 second of greater ...
Anderson Sandra D - - 2003
BACKGROUND: There has been an increase in the number and percentage of athletes competing in Olympic Games notifying use of beta2-agonists, from 1.7% at Los Angeles (1984) to 5.5% at Sydney (2000). For Salt Lake City (2002), the International Olympic Committee requested objective evidence to use beta2-agonists for asthma or ...
Komotar Ricardo J - - 2002
OBJECTIVE: Hydrocephalus requiring shunt placement is a common complication after aneurysmal subarachnoid hemorrhage (aSAH). Previous investigations suggest that fenestration of the lamina terminalis during microsurgery for aSAH may be associated with a reduced rate of shunt-dependent hydrocephalus. We report a retrospective analysis correlating fenestration of the lamina terminalis with decreased ...
Kume Hiroaki - - 2002
1. Recently, a patch formulation of tulobuterol, a beta-adrenoceptor (AR) agonist, has been developed using a transdermal delivery system. The present study was designed to determine whether beta-AR function and asthma control were affected by the sustained-released beta-AR agonist. 2. Tulobuterol (2 mg) was applied daily for 8 weeks to ...
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