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Capomaccio S - - 2010
A large proportion of mammalian genomes is represented by transposable elements (TE), most of them being long interspersed nuclear elements 1 (LINE-1 or L1). An increased expression of LINE-1 elements may play an important role in cellular stress-related conditions exerting drastic effects on the mammalian transcriptome. To understand the impact ...
Davidson Elizabeth J - - 2010
To (1) assess upper airway function by videoendoscopy in horses performing poorly after laryngoplasty and (2) establish whether dynamic collapse of the left arytenoid can be predicted by the degree of resting postsurgical abduction. Case series. Horses that had left laryngoplasty (n=45). Medical records (June 1993-December 2007) of horses evaluated ...
Meyer N D - - 2010
Prolonged equine exercise can cause hypochloraemic alkalosis and hypokalaemia secondary to the loss of hypertonic sweat. Movement of ions in and out of erythrocytes during exercise may help regulate acid-base balance and changes in plasma ion concentrations. The extent to which this happens during prolonged equine exercise has not been ...
Pigott J H JH Department of Clinical Sciences, Cornell University, NY, - - 2010
The relationship between dorsal displacement of the soft palate (DDSP) and swallowing is unclear. To quantify the relationship between DDSP and swallowing in horses at exercise. The frequency of swallowing increases immediately prior to DDSP in horses at exercise. Videoendoscopic and upper airway pressure data were collated from horses with ...
Alberghina Daniela - - 2011
This study was designed to examine the influence of sub-maximal exercise on purine and pyrimidine catabolism in horses. Ten horses were initially trained for 12 weeks at the end of which they underwent a standardized exercise test (SET); venous blood samples were taken at rest, 5 and 30 min after the SET. ...
Matsuura Akihiro - - 2010
Horse trekking (HT) is having a stroll on a horse along a walking trail in a forest, field, and/or sandy beach. Generally in HT, horses exercise in tandem line outside the riding facilities. Because the leading horse will be confronted with stressors in the forefront, we hypothesized that the leading ...
Lindner A - - 2011
This study examined the effect of exercising horses five times per fortnight with two bouts of 5 min duration at their v(10) with 2 days between consecutive exercise sessions. Five Anglo-Arabian horses were treadmill-conditioned for 6 weeks. A standardized exercise test (SET) was performed at the beginning of the conditioning period (CP) to ...
Cehak Anja - - 2010
Dynamic nasopharyngeal collapse with upper airway obstruction is an important cause of exercise intolerance in performance horses. Its underlying pathophysiology is not fully understood. We hypothesize that head position affects pharyngeal diameter, and thus head position may be a contributing factor to nasopharyngeal obstruction. Fifteen adult healthy horses were subjected ...
Muñoz Ana - - 2011
This study investigated the effect of hypertonic dehydration on exercise in horses. Valencian draft horses (n=43) with hypertonic dehydration following water and food deprivation and competing in pulling events (COM), were compared to euhydrated horses (n=11) during a pulling exercise test (PET). Both groups were divided into bodyweight (BW) categories ...
Xie Lin - - 2011
Equine degenerative suspensory ligament desmitis (DSLD) is a debilitating condition that has limited response to rest and stall confinement. This study was designed to test the hypothesis that mild to moderate DSLD is not worsened by consistent exercise. Paso Fino and Peruvian Paso horses (two normal horses and four horses ...
Schefer K D - - 2010
BACKGROUND: Stress echocardiography is used to diagnose myocardial dysfunction in horses, but current methods are not well standardized. The influence of heart rate (HR) on measurements is largely unknown. OBJECTIVES: To investigate the use of 2-dimensional echocardiography (2DE), anatomical M-mode (AMM), tissue Doppler imaging (TDI), and 2D speckle tracking (2DST) ...
Romero Alfredo - - 2010
A 3-year-old Thoroughbred was presented for evaluation of hematuria post exercise. On physical examination, an enlarged kidney was identified, as well as serum biochemical abnormalities such as an elevated creatine kinase (CK) and hypoalbuminemia. The kidney was removed laparoscopically and a nephroblastoma was identified.
Kawcak Chris E - - 2010
Objective-To determine the effects of exercise at an early age on tissues in the metacarpophalangeal joints of horses. Animals-Twelve 18-month-old horses. Procedures-All horses were pasture reared, but 6 horses had additional exercise starting at 3 weeks of age until 18 months of age. At that time, computed tomography, articular cartilage ...
Allen K J - - 2010
REASONS FOR PERFORMING STUDY: To date there is no information on the comparison of the more recently documented technique of performing endoscopy during ridden exercise in the field, with the more traditional method of endoscopy during high-speed treadmill exercise. OBJECTIVES: To compare the results of upper respiratory tract endoscopy in ...
Authie E C - - 2010
Equine antidoping rules were established to prevent a horse's performance being altered after the administration of prohibited substances, including approved drugs used for legitimate treatment. Veterinarians have to advise owners or trainers on appropriate withholding times to guarantee that their horses may safely compete after drug administration. In order to ...
Kawcak Chris E - - 2010
OBJECTIVE: To determine the effects of exercise at an early age on tissues in the metacarpophalangeal joints of horses. ANIMALS: Twelve 18-month-old horses. PROCEDURES: All horses were pasture reared, but 6 horses had additional exercise starting at 3 weeks of age until 18 months of age. At that time, computed ...
Williamson K K - - 2010
BACKGROUND: Omeprazole and famotidine both reduce severity of exercise-induced gastritis, but administering famotidine is easier than administering omeprazole during racing competition. HYPOTHESIS: Famotidine is more efficacious than no treatment in reducing severity of exercise-induced gastritis; and high-dose famotidine is more efficacious than omeprazole in reducing severity of exercise-induced gastritis. ANIMALS: ...
Lindner A E - - 2010
The speed producing the maximal lactate steady state (maxLASS) is supposed to be the optimal speed to condition for endurance. The maxLASS was defined as the maximal speed at which the blood lactate concentration ([LA]) between the 5th and the 25th min of continuous exercise did not increase by more ...
Muñoz A - - 2010
Arginine vasopressin (AVP) is released in response to depletion of the effective circulating blood volume. Endurance horses might develop exhaustion because loss of water and electrolytes in sweat with hypovolaemia and electrolytes abnormalities. Therefore, AVP should act in the control of volemia in these animals. This research evaluates the differences ...
Giordano Alessia A Unit of General Pathology and Parasitology, Department of Veterinary Pathology, Hygiene and Public Health, University of Milan, Via Celoria 10, 20133 Milano, - - 2010
Exercise-induced pulmonary hemorrhage (EIPH) commonly occurs in race horses. Thromboelastometry (TEM) investigates the whole hemostatic process by evaluating the viscoelastic properties of the blood clot from its formation to fibrinolysis. The aim of this study was to assess whether horses with EIPH have abnormal thromboelastometric profiles. Intrinsic and extrinsic pathways, ...
Lindner A E - - 2010
The objective of the study was to examine the validity of v(4) [velocity run under the defined conditions inducing 4 mmol/L of blood lactate concentration ([LA])] and v(200) (velocity run under the defined conditions inducing a heart rate of 200 beats/min) to differentiate performance level among Standardbred racehorses. For this ...
Faramarzi Babak - - 2009
OBJECTIVE: To quantitate changes in hoof wall growth and hoof morphology induced by mild exercise in Standardbreds. ANIMALS: 18 Standardbreds. PROCEDURES: Horses were exercised at approximately 6 m/s (4,200 to 5,600 m/d) on 4 d/wk for 17 weeks. Both exercise (n = 9) and nonexercise (control group; 9) groups were ...
Cramp P - - 2009
REASONS FOR PERFORMING STUDY: Little is known about the efficacy of bilateral ventriculectomy (VE) or bilateral ventriculocordectomy (VCE) in draught horses. OBJECTIVES: To compare the effect of VE and VCE on upper airway noise in draught horses with recurrent laryngeal neuropathy (RLN) by use of quantitative sound analysis techniques. HYPOTHESIS: ...
Haggett Emily - - 2010
Exercise causes an increase in the production of reactive oxygen species, which can result in oxidant/antioxidant disequilibrium. Deficiency of antioxidants can further alter this balance in favor of pro-oxidation. Selenium (Se) is one of many antioxidant catalysts, as a component of the glutathione peroxidase enzymes. Soils and forages vary widely ...
van den Hoven R - - 2010
The time-dependent changes in intramuscular amino acid (AA) levels caused by exercise and by feeding a protein/AA supplement were analysed in nine horses. Horses were submitted to a total of four standardized exercise tests (SETs). Amino acid concentrations were determined prior to, immediately after, 4 and 18 h after exercise. ...
McCue Molly E - - 2009
OBJECTIVE: To compare effects of corn oil or a 7-carbon fat (triheptanoin) on acylcarnitine, lipid, and carbohydrate metabolism in plasma or muscle of exercising horses. ANIMALS: 8 Thoroughbred geldings. PROCEDURES: Horses received isocaloric diets containing 650 mL of oil (triheptanoin or corn oil)/d for 18 or 25 days in a ...
Perez-Moreno Cecilia I - - 2009
The objective was to quantify the effect of furosemide and carbazochrome on exercise-induced pulmonary hemorrhage (EIPH) in Standardbred horses using red blood cell count and hemoglobin concentration in bronchoalveolar lavage (BAL) fluid. Six healthy Standardbred horses with prior evidence of EIPH performed a standardized treadmill test 4 h after administration ...
Fureix Carole - - 2009
Handling is a crucial component of the human-horse relationship. Here, we report data from an experiment conducted to assess and compare the effect of two training methods. Two groups of six Welsh mares were trained during four sessions of 50 min, one handled with traditional exercises (halter leading, grooming/brushing, lifting ...
Leprêtre P-M - - 2009
Measurements of minute ventilation (VE) and expired oxygen and carbon dioxide fractions (FeO2 and FeCO2) were measured at rest and during exercise in seven warmblood horses performing two consecutive standardised incremental treadmill exercise tests at submaximal speed, using the portable K4b2 telemetric unit and the laboratory Quark metabolic cart in ...
Lindner A - - 2009
The velocity at which blood lactate concentration ([LA]) of 4 mmol/L is reached (v(4)) is widely used to determine fitness, but there are few published data on using [LA] as a guide for the exercise speed for training in horses. In this study, the effect of 3 conditioning programs with ...
Nieto Jorge E - - 2009
Objective-To develop a protocol to induce and maintain gastric ulceration in horses and to determine whether gastric ulceration affects physiologic indices of performance during high-speed treadmill exercise. Animals-20 healthy Thoroughbreds. Procedures-Each horse was acclimatized to treadmill exercise during a 2-week period. Subsequently, baseline data were collected (day 0) and each ...
Ducharme Normand G - - 2009
OBJECTIVE: To evaluate whether administering a tart cherry juice blend (TCJB) prior to exercise would reduce skeletal and cardiac muscle damage by decreasing the inflammatory and oxidative stress response to exercise in horses. ANIMALS: 6 horses. PROCEDURES: Horses were randomly allocated into 2 groups in a crossover study with a ...
Nieto Jorge E JE Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, CA 95616, - - 2009
To develop a protocol to induce and maintain gastric ulceration in horses and to determine whether gastric ulceration affects physiologic indices of performance during high-speed treadmill exercise. 20 healthy Thoroughbreds. Each horse was acclimatized to treadmill exercise during a 2-week period. Subsequently, baseline data were collected (day 0) and each ...
Richard Eric A - - 2010
Any disorder impairing a performance horse's ability to ventilate its lungs and exchange oxygen compromises exercise performance in any discipline. Since bronchoalveolar lavage was described in horses in the early 1980s, laboratory evaluation of respiratory fluids, along with clinical and functional assessment of the respiratory system, has become a relevant ...
Richard Eric A - - 2010
The objectives of this study were to determine the prevalence of sub-clinical diseases in poorly-performing Standardbred horses, compare their physiological response to exercise with control horses, and identify predictive parameters of poor-performance. Fifty horses underwent thorough clinical and ancillary examinations, including haematological and biochemical evaluation, Doppler echocardiography, standardised exercise tests ...
Hubbell J A E - - 2009
REASON FOR PERFORMING STUDY: Increased doses of detomidine are required to produce sedation in horses after maximal exercise compared to calm or resting horses. OBJECTIVES: To determine if the pharmacokinetics of detomidine in Thoroughbred horses are different when the drug is given during recuperation from a brief period of maximal ...
Freire R - - 2009
REASONS FOR PERFORMING STUDY: It is unknown if different locomotor activities are equally effective at meeting the stabled horse's need for exercise and if they attenuate unwanted behaviour. HYPOTHESIS: Alternative forms of exercise influence the intensity of locomotor activities during a period of turn-out (the so-called rebound effect) and the ...
Verheyen Kristien L P - - 2009
This study aimed to determine the effects of exercise on racecourse performance in horses racing on the flat. Daily exercise and race records were obtained over a 2-year period for a cohort of racehorses in training for which injury data were also available. Multivariable regression techniques were used to investigate ...
Desmaizieres L-M - - 2009
REASONS FOR PERFORMING STUDY: High speed treadmill endoscopy provides a true assessment and diagnosis of the dynamic obstructions of the upper equine respiratory tract (DO-URT). However, treadmills do not always allow reproduction of the exact conditions of dynamic collapse of the URT. The availability of on-board endoscopes, which could be ...
McKenzie Erica C - - 2009
Chronic exertional rhabdomyolysis represents a syndrome of recurrent exercise-associated muscle damage in horses that arises from a variety of etiologies. Major advances have been made in the understanding of the pathophysiology of this disease, and causative genetic defects have been recently identified for two conditions-polysaccharide storage myopathy of quarter horses, ...
Pollock P J - - 2009
REASONS FOR PERFORMING STUDY: There are potential advantages to imaging the upper portion of the respiratory tract (URT) of horses during ridden exercise. With the advent of a wireless endoscope, this is now possible. However, there has been no detailed validation of the technique and findings have not been compared ...
Lepeule J - - 2009
Developmental Orthopaedic Disease (DOD) in limb joints of horses is frequent and is a common cause of pain and lameness. DOD is a multifactorial disease involving genetics, growth, feeding practices and exercise conditions leading to joint injuries. However, there is no clear understanding of the contribution of each factor. The ...
Decurnex V - - 2009
REASONS FOR PERFORMING STUDY: Most lameness in horses relates to foot problems and may be associated with changes in hoof shape, but there is a lack of information on the influence of normal exercise on hoof shape. OBJECTIVES: To investigate the effect of training on proximal hoof circumference in young ...
Breuhaus B A - - 2009
BACKGROUND: This study was performed to determine whether anhidrotic horses have altered thyroid function compared with horses that sweat normally. HYPOTHESIS: Anhidrotic horses have normal thyroid function. ANIMALS: Ten client-owned horses with clinical signs of anhidrosis were paired with 10 horses living in the same environment that had normal sweat ...
Baccarin R Y A - - 2009
A controlled study was designed in order to evaluate the effects of medial patellar desmotomy (MPD), combined with exercise restriction, on clinically and radiographically normal femoropatellar joints, and to identify the patellar instability by radiographic examination. MPD was performed on the right hind limb and the horses were rested for ...
Tobari Hiroko - - 2009
OBJECTIVES: Prevention of horse-related injuries is considered difficult because horse behavior is unpredictable. Therefore, risk factors for injuries related to professional horse racing need to be investigated. We conducted a study to determine whether body mass index (BMI) and gamma-glutamyltransferase (GGT) levels are associated with professional horse racing-related injuries. METHODS: ...
Fazio F - - 2009
The aim of the present work was to evaluate the influence of exercise on serum homocysteine and oxidative stress in Thoroughbreds during official races. For our study, ten Thoroughbred mares, 5 years old and clinically healthy, were used. The horses were trained to take part in an official 2100 meter ...
Hughes K J - - 2009
REASONS FOR PERFORMING STUDY: Acute monensin intoxication in equids is well described; however, the long-term effects of sublethal intoxication and ability to return to previous use are less well understood. Long-term observations may allow improved estimation of prognosis in cases of sublethal intoxication. OBJECTIVES: To assess horses and ponies exposed ...
Kawahara Hidejiro - - 2009
Dai-kenchu-to (DKT) has attracted attention as a drug that improves the symptoms of postoperative ileus. However, the detailed mechanism of its action still remains unknown. The effect of DKT on colonic motility was herein evaluated using an original method. Eight healthy male volunteers who understood the purpose of this study ...
Cappelli Katia - - 2009
The stress response is a critical factor in the training of equine athletes; it is important for performance and for protection of the animal against physio-pathological disorders.In this study, the molecular mechanisms involved in the response to acute and strenuous exercise were investigated using peripheral blood mononuclear cells (PBMCs). Quantitative ...
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