Background: Even though specific agents for the treatment of patients with pulmonary hypertension (PH) are available, in PH patients, physical capacity and quality of life (QoL) are often restricted and survival is reduced. Objectives: This study prospectively investigated the long-term effects of respiratory and exercise training in patients with severe ...

This study was undertaken to assess the effects of dehydroepiandrosterone (DHEA) administration and exercise training on muscular DHEA and 5α-dihydrotestosterone (DHT) levels and hyperglycemia in diet-induced obese and hyperglycemic rats. After 14 wk of a high-sucrose diet, obese male Wistar rats were assigned randomly to one of three 6-wk regimens: ...

Rodríguez-Marroyo, JA, Pernía, R, Cejuela, R, García-López, J, Llopis, J, and Villa, JG. Exercise intensity and load during different races in youth and junior cyclists. J Strength Cond Res 25(2): 511-519, 2011-This study analyzed and compared the exercise intensity exerted by Youth and Junior cyclists in single-day and stage races. ...

The present study examined the working hypothesis that moderate-intensity exercise is associated with coping-oriented marijuana use motives through its association with the fear of somatic arousal (ie, anxiety sensitivity). Using data from 146 young adult current marijuana users, we found evidence consistent with this hypothesis. Specifically, moderate-intensity exercise was associated ...

In cognitive-behavioral treatments for obesity, self-regulation is thought to be a strong predictor of behavioral change, but it is rarely directly measured in intervention research. Thus, how self-regulation interacts with other psychological variables regarding treatment effects is largely unknown. In this preliminary field study, self-regulatory skills were directly measured and ...

Lumbosacral radiculopathy is relatively common, and most cases resolve with appropriate conservative management. Along with pain control, the mainstay of treatment is a comprehensive rehabilitation program to correct for biomechanical factors that adversely affect spinal stability and predispose the patient to recurrent pain. Developing an appropriate treatment plan depends on ...

This study was conducted to determine the effects of Phellinus linteus (PL) on serotonin synthesis in the brain and on the expression of monocarboxylate transporters (MCTs) in muscles during exhaustive exercise in rats. In this study, 60 male Sprague-Dawley rats were divided into the following 6 groups: control; exercise; exercise ...

Cannabis dependence is a significant public health problem. Because there are no approved medications for this condition, treatment must rely on behavioral approaches empirically complemented by such lifestyle change as exercise. To examine the effects of moderate aerobic exercise on cannabis craving and use in cannabis dependent adults under normal ...

The purpose of this study was to determine if Omega 3 Chia seed loading is a viable option for enhancing sports performance in events lasting >90 minutes and allow athletes to decrease their dietary intake of sugar while increasing their intake of Omega 3 fatty acids. It has been well ...

Background: Major depressive disorder (MDD) in pregnancy or antenatal depression poses unique treatment challenges and has serious consequences for mothers, unborn babies, and families when untreated. This review presents current knowledge on exercise during pregnancy, antidepressant effects of exercise, and the rationale for the specific study of exercise for antenatal ...

Major depressive disorder (MDD) in pregnancy or antenatal depression poses unique treatment challenges and has serious consequences for mothers, unborn babies, and families when untreated. This review presents current knowledge on exercise during pregnancy, antidepressant effects of exercise, and the rationale for the specific study of exercise for antenatal depression. ...

To examine a 1-year follow-up of a 4-month, controlled clinical trial of exercise and antidepressant medication in patients with major depressive disorder (MDD). In the original study, 202 sedentary adults with MDD were randomized to: a) supervised exercise; b) home-based exercise; c) sertraline; or d) placebo pill. We examined two ...

Osteoarthritis (OA) is a degenerative joint disease with a high prevalence among older people. To date, the pathogenesis of the disease and the link between muscle function and OA is not entirely understood. As there is no known cure for OA, current research focuses on prevention and symptomatic treatment of ...

Treatment for exercise-induced bronchospasm and exercise-induced asthma includes both pharmacologic and nonpharmacologic options. Pharmacologic agents that have been proven to be effective for treating these conditions include short- and long-acting β2-adrenoceptor agonists, mast cell-stabilizing agents, anticholinergics, leukotriene receptor antagonists, and inhaled corticosteroids (ICS). When selecting the most appropriate medication, factors ...

In the last years, phototherapy has becoming a promising tool to improve skeletal muscle recovery after exercise, however, it was not compared with other modalities commonly used with this aim. In the present study we compared the short-term effects of cold water immersion therapy (CWIT) and light emitting diode therapy ...

The double product is the product of the heart rate and systolic blood pressure. The double product break point (DPBP) is a physiologic threshold that occurs at similar exercise intensities to that of the ventilatory threshold (VT). The influence of aerobic exercise training on the DPBP has not yet been ...

The purpose of this study was to determine if sex differences are present in exercise-induced inspiratory muscle function in untrained humans. Eight young untrained women (23.8 ± 1.5 y, VO2max = 33.7 ± 4.0 mL/kg/min) and men (26.1 ± 2.0 y, VO2max = 36.7 ± 1.2 mL/kg/min) performed high-intensity cycling ...

We examined the influence of operational lung volumes and mean inspiratory flow on the amplitude of the slow component of O₂uptake (V(O)₂(SC) ) during constant-load cycling performed below and above the respiratory compensation threshold (RCT) in young (24±1yr), healthy individuals (n=10). Subjects demonstrated a significantly greater rise in expiratory reserve ...

For many years, experts have been debating the pros and cons of exercise for depression. Proponents of exercise for depression point to those clinical trials which have shown that exercise improves mood, while sceptics point out the methodological problems in many of the apparently positive trials, and the uncertainties around ...

The purpose of this study was to test the transient hypofrontality theory (Dietrich, 2003) by examining the influence of exercise intensity on executive control processes during and following submaximal exercise. Thirty participants (13 female) exercised for 30 min at ventilatory threshold (VT) or at 75% of VT. The Contingent Continuous ...

To validate a new device designed to measure ventilation (V(E)), tidal volume (V(T)), inspiratory time (T(I)), and expiratory time (T(E)) during daily life activities. The anteroposterior displacement of the rib cage and abdomen and the axial displacements of the chest wall and the spine were measured using two pairs of ...

The aim of present study was to compare the alterations in electromyography signs with Ventilatory Threshold (VT). Had been part of the study eight men, amateur cyclists and triathletes (25.25 +/- 6.96 years), that they had exercised themselves in a mechanical cicloergometer, a cadence of 80 RPM and with the ...

The purpose of this study was to compare the prevalence and implications of expiratory flow limitation (EFL) during exercise in boys and girls. Forty healthy, prepubescent boys (B; n=20) and girls (G; n=20) were tested. Subjects completed pulmonary function tests and an incremental cycle maximal oxygen uptake (VO2max) test. EFL ...

OBJECTIVE: To determine whether two types of exercise--breathing retraining (BRT) and inspiratory muscle training (IMT)--improve on cardiopulmonary functions and exercise tolerance in patients with stroke. DESIGN: A randomized controlled trial. SETTING: Education and research hospital. SUBJECTS: Forty-five inpatients with stroke (24 men, 21 women) were recruited for the study. The ...

Expiratory flow limitation (EFL) during exercise may be overestimated or falsely detected when superimposing tidal breaths within a pre-exercise maximal expiratory flow volume (MEFV) curve due to thoracic gas compression (TGC) and bronchodilation. Accordingly, the purpose of this study was to determine the effects of TGC and bronchodilation on the ...

We hypothesized that heart failure patients with inspiratory muscle weakness (IMW) present greater peripheral chemoreflex responsiveness and augmented exercise ventilatory oscillation compared to patients with preserved inspiratory muscle strength. We studied 19 heart failure patients: 9 with IMW (maximal inspiratory pressure [PImax]<70% of predicted) and 10 with preserved inspiratory muscle ...

Affective responses to exercise may be important for improving adherence to regular programs of exercise. The present study sought to determine whether resting frontal EEG asymmetry, an individual difference measure of affective style, is predictive of affective responses to exercise performed at distinct intensities standardized relative to a metabolic landmark ...

The submaximal electromyographic fatigue threshold test (EMG(FT)) has been shown to be highly correlated to ventilatory threshold (VT) as determined from maximal graded exercise tests (GXTs). Recently, a prediction equation was developed using the EMG(FT) value to predict VT. The aim of this study, therefore, was to determine if this ...

The Scoliosis Rehabilitation model begins with the correct diagnosis and evaluation of the patient, to make treatment decisions oriented to the patient. The treatment is based on observation, education, scoliosis specific exercises, and bracing. The state of research in the field of conservative treatment is insufficient. There is some evidence ...

Dysfunction of spinal stability seems to be one of the causes of low back pain (LBP). It is thought that a large number of muscles have a role in spinal stability including the pelvic floor muscle (PFM). The purpose of this study was to investigate the effect of PFM exercise ...

: To assess differences between women and men in developing an action plan for the management of their type 2 diabetes mellitus (DM). : We chose a convenience sample of the first 153 patients who participated in a four-part educational class focused on the management of type 2 DM. The ...

Small increases in external dead space (V(D)) augment the exercise ventilatory response via a neural mechanism known as short-term modulation (STM). We hypothesized that breathing mechanics would differ during exercise, increased V(D) and STM. Men were studied at rest and during cycle exercise (10-50W) without (Control) and with added V(D) ...

Regular chest physiotherapy is advocated in non-cystic fibrosis bronchiectasis despite little evidence supporting its routine use. This study aimed to establish the efficacy of regular chest physiotherapy in non-cystic fibrosis bronchiectasis compared with no regular chest physiotherapy. 20 patients not practising regular chest physiotherapy were enrolled in a randomised crossover ...

The purpose of this study was to assess the efficacy of inspiratory flow resistive loading (IFRL) on respiratory muscle function, exercise performance and cardiopulmonary and metabolic responses to exercise. Twenty-four recreational road runners (12 male) were randomly assigned from each gender into an IFRL group (n=8) and sham-IFRL group (n=8), ...

To determine whether endurance-trained cyclists (T; n = 10) have a superior blood-respiratory buffering for metabolic acidosis relative to untrained subjects (UT; n = 10) during variable intensity exercise (VAR). On three occasions, T and UT pedaled for 24 min alternating high- and low-intensities as percentage of their second ventilatory ...

It is not known whether the high total work of breathing (WOB) in exercising women is higher due to differences in the resistive or elastic WOB. Accordingly, the purpose of this study was to determine which factors contribute to the higher total WOB during exercise in women. We performed a ...

We examined the relationship between skin surface lactate concentration on working muscle and heart rate during continuous graded cycling exercise. Sixteen healthy male volunteers participated in this study. A plastic container with 100 μl 1% ethanol was put on the skin surface on the belly of rectus femoris muscle. The ...

We examined 26 professional riders during time trial (TT) competitions of the Grand Tours of cycling (Tour de France and Vuelta Espana; 1997-2003) for the exertional characteristics of contending vs. non-contending (i.e., support) riders. We categorized HR time during TT into training impulse (TRIMP) defined from seasonal VO2max testing [Phase ...

INTRODUCTION: In patients with heart failure (HF), end-tidal CO2 pressure (PetCO2) is related to ventricular function at rest and has been shown to predict prognosis. However, little is known about the association between ventricular performance and PetCO2 responses to exercise. METHODS: Forty-eight patients with HF and 13 normal subjects underwent ...

We have previously shown that unilateral or bilateral lesions of the lateral parabrachial nucleus (LPBN) in anesthetized, vagotomized rats markedly and selectively attenuate the shortening of expiratory duration (T(E)) during hypoxia without appreciably affecting all other hypoxic response components. Here, we report that unilateral LPBN lesion by kainic acid in ...

Human ventilation at rest exhibits complexity and chaos. The aim of this study was to determine whether suprapontine interferences with the automatic breathing control could contribute to ventilatory chaos. We conducted a post hoc analysis of a previous study performed in awake volunteers exhibiting cortical pre-motor potentials during inspiratory loading. ...

Respiratory muscle fatigue has been reported following short bouts of high-intensity exercise, and prolonged, moderate-intensity exercise, as evidenced by decrements in inspiratory and expiratory mouth pressures. However, links to functionally relevant outcomes such as breathing effort have been lacking. The present study examined dyspnoea and leg fatigue during a treadmill ...

OBJECTIVE: We performed a systematic review to determine the effect of inspiratory muscle training (IMT) on inspiratory muscle strength and endurance, exercise capacity, dyspnoea and quality of life for adolescents and adults living with cystic fibrosis. DATA SOURCES: MEDLINE, EMBASE and CINAHL electronic databases were searched up to January 2008. ...

AIM: The aim of the investigation was to assess the effects of the resistive inspiratory muscle training (IMT) in elite male rowers. METHODS: Fifteen senior rowers were assayed for the maximal inspiratory mouth pressure (PImax) and maximal oxygen uptake (VO2max), and then randomized into two groups: the control and the ...

The aim of this study was to identify the physiological mechanisms of exertional respiratory discomfort (breathlessness) in pregnancy by comparing ventilatory (breathing pattern, airway function, operating lung volumes, oesophageal pressure (P(oes))-derived indices of respiratory mechanics) and perceptual (breathlessness intensity) responses to incremental cycle exercise in 15 young, healthy women in ...

Women have smaller airways and lung volumes and lower resting maximal expiratory flow rates relative to men. Female athletes develop expiratory flow limitation more frequently than male athletes, and they have greater increases in end-expiratory and end-inspiratory lung volume at maximal exercise. Women use a greater fraction of their ventilatory ...

Although reduced blood lactate concentrations ([lac(-)](B)) have been observed during whole-body exercise following inspiratory muscle training (IMT), it remains unknown whether the inspiratory muscles are the source of at least part of this reduction. To investigate this, we tested the hypothesis that IMT would attenuate the increase in [lac(-)](B) caused ...

The aim of this thesis was to examine the impact of modifications to ventilatory constraint in populations who have reductions in expiratory flow and ventilatory limitations during exercise. The first study examined the effect of the self-contained breathing apparatus (SCBA) regulator on work of breathing (WOB) and lung volume changes ...

BACKGROUND AND OBJECTIVE: Thixotropy conditioning of inspiratory muscles changes the end-expiratory position of the respiratory system during resting breathing. We examined the immediate effects of thixotropy conditioning of inspiratory muscles on chest wall inflation induced by CPAP. METHODS: A cross-over design study was performed in 13 healthy men. Operating chest ...

This study examined the patterning of acute affective responses to prescribed and self-selected exercise intensities in a young adolescent population. Twenty-two young adolescents (13.3 +/- .33 years) completed a maximal exercise test to identify ventilatory threshold (VT). Participants then completed two prescribed intensities (one set above and one below the ...