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Marini Cecilia C CNR Institute of Bioimaging and Molecular Physiology, Section of Genoa c/o Nuclear Medicine, Pad. Sommariva, IRCCS AOU San Martino-National Institute for Cancer Research, L.go R. Benzi, 10, 16132, Genoa, Italy, - - 2014
Reversible ischaemia at radionuclide myocardial perfusion imaging (MPI) accurately predicts risk of cardiac death and nonfatal myocardial infarction (major adverse cardiac events, MACE). This prognostic penetrance might be empowered by accounting for exercise tolerance as an indirect index of ischaemia severity. The present study aimed to verify this hypothesis integrating ...
Souza-Junior Tp T Department of Physical Education, Federal University of Parana (UFPR), Curitiba, PR, - - 2014
Reactive oxygen species are produced during anaerobic exercise mostly by Fe ions released into plasma and endothelial/muscle xanthine oxidase activation that generates uric acid (UA) as the endpoint metabolite. Paradoxically, UA is considered a major antioxidant by virtue of being able to chelate pro-oxidative iron ions. This work aimed to ...
Rosenbaum S S Musculoskeletal Division, The George Institute for Global Health and School of Public Health, University of Sydney, Sydney, NSW, Australia; St John of God Health Care Richmond Hospital, Sydney, NSW, - - 2014
To investigate the impact of a 12-week exercise programme in addition to usual care for post-traumatic stress disorder (PTSD). An assessor-blinded randomized controlled trial was conducted among 81 participants with a DSM-IV-TR diagnosis of primary PTSD. Participants were recruited after admission to an in-patient programme at a private hospital. Participants ...
Stelzer I I Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, - - 2014
Although amateur sports have become increasingly competitive within recent decades, there are as yet few studies on the possible health risks for athletes. This study aims to determine the impact of ultra-endurance exercise-induced stress on the number and function of circulating hematopoietic progenitor cells (CPCs) and hematological, inflammatory, clinical, metabolic, ...
Reilly E T C ET Urogynaecology Unit, Department of Obstetrics and Gynaecology, Derriford Hospital, Plymouth, - - 2014
To test whether supervised pelvic floor exercises antenatally will reduce the incidence of postpartum stress incontinence in at-risk primigravidae with bladder neck mobility, ultrasonically proven. Single blind, randomised controlled trial. Antenatal clinic in a UK NHS Trust Hospital. Two hundred and sixty-eight primigravidae attending an antenatal clinic at approximately 20 weeks ...
Yoon Gun-Ae GA Department of Food and Nutrition, College of Natural Science and Human Ecology, Dong-eui University, 176 Eomgwangno, Busanjin-gu, Busan 614-714, - - 2014
Isoflavones are widely believed to be beneficial to human health, in relation to their antioxidant potentials. Exercise can cause an imbalance between reactive oxygen species (ROS) and antioxidants. This study was conducted in order to investigate the ability of isoflavones in amelioration of oxidative stress induced by exercise. Male Sprague-Dawley ...
Inoue K K Laboratory of Exercise Biochemistry and Neuroendocrinology, Faculty of Health and Sport Sciences, University of Tsukuba, Tsukuba, - - 2014
Although exercise training improves hippocampus-related cognition, the optimum exercise intensity is still disputed. Based on the lactate threshold (LT, approximately 20 m/min on treadmill) of rats, we have shown that 2 weeks of training with stress-free mild exercise (ME, <LT), but not intense exercise (IE, >LT), comprising exercise stress, promotes adult ...
Peternelj Tina Tinkara TT Antioxidant Research Group, School of Human Movement Studies, The University of Queensland, St Lucia, Brisbane, QLD, 4072, Australia, - - 2014
Post-translational modification of intracellular proteins with O-linked β-N-acetylglucosamine (O-GlcNAc) profoundly affects protein structure, function, and metabolism. Although many skeletal muscle proteins are O-GlcNAcylated, the modification has not been extensively studied in this tissue, especially in the context of exercise. This study investigated the effects of glutathione depletion and acute exercise ...
Ciliberti P P Great Ormond Street Hospital for Children, London, WC1N 3JH, - - 2014
Although exercise stress echocardiography (ESE) is a well-validated technique in adult population, its use in children is quite limited. We aimed to assess the feasibility, the safety and the reproducibility of ESE, using on-line scanning in semi-supine cyclo-ergometer protocol in a large pediatric population. Between July 2008 and January 2013, ...
Abreu C C CC Graduate Program in Cardiovascular Sciences, Federal Fluminense University (UFF), Niteroi, Brazil. Electronic address: - - 2014
Patients with chronic kidney disease (CKD) have various metabolic disorders caused by a chronic state of oxidative stress and inflammation, and recently, nuclear factor-erythroid 2-related factor 2 (Nrf2) has emerged as a factor that plays a significant role in cellular protection against oxidative stress and inflammation. This transcription factor when ...
de Almeira Rodrigues Barbara B 1Laboratory of Molecular Biology of Exercise (LABMEX) and Center for Biological Assays (CEB), Center for Research in Sport Science (CEPECE), School of Applied Science, University of Campinas (UNICAMP), Limeira, São Paulo, Brazil; 2Laboratory of Exercise Biochemistry and Physiology, Health Science Unit, University of Extremo Sul Catarinense (UNESC), Criciúma, SC, Brazil; 3School of Physical Education and Sport of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil; 4São Paulo University State (UNESP), Rio Claro, SP, - - 2014
To evaluate the effects of acute exercise on the TRB3 protein levels and interaction between TRB3/Akt proteins in the hypothalamus of obese rats. In addition, we evaluated the relationship between TRB3 and endoplasmic reticulum stress (ER stress) and verified whether an acute exercise session is able to influence these processes. ...
Slattery Katie K Sport and Exercise Discipline Group, Faculty of Health, University of Technology, Sydney, NSW, Australia, - - 2014
During periods of intensified physical training, reactive oxygen species (ROS) release may exceed the protective capacity of the antioxidant system and lead to dysregulation within the inflammatory and neuroendocrinological systems. Consequently, the efficacy of exogenous antioxidant supplementation to maintain the oxidative balance in states of exercise stress has been widely ...
Tamm Maria M Institute of Psychology, University of Tartu, Estonia; Doctoral School of Behavioural, Social and Health Sciences, University of Tartu, Estonia. Electronic address: - - 2014
Cognitive performance is impaired during prolonged exercise in hot environment compared to temperate conditions. These effects are related to both peripheral markers of heats stress and alterations in CNS functioning. Repeated-exposure to heat stress results in physiological adaptations, and therefore improvement in exercise capacity and cognitive functioning are observed. The ...
Ryerson A Blythe AB Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, - - 2014
Surveillance for anthracycline cardiotoxicity in cancer survivors typically utilizes resting M-mode and two-dimensional echocardiography, which are insensitive to detection of subtle myocardial changes. We examined childhood cancer survivors treated with anthracyclines during exercise using various echocardiography techniques to investigate if these tools can better detect subclinical cardiac dysfunction. We recruited ...
Erdei Tamás T Wales Heart Research Institute, Cardiff University, Cardiff, - - 2014
Cardiac function should be assessed during stress in patients with suspected heart failure with preserved ejection fraction (HFPEF), but it is unclear how to define impaired diastolic reserve. We conducted a systematic review to identify which pathophysiological changes serve as appropriate targets for diagnostic imaging. We identified 38 studies of ...
Ghosh Reena M RM Division of Pediatric Cardiology, Department of Pediatrics, The Children's Hospital at Montefiore - Albert Einstein College of Medicine, 3415 Bainbridge Ave, Bronx, NY, 10467, - - 2014
Exercise testing is commonly performed in children for evaluation of cardiac disease. Few data exist, however, on the prevalence, types of arrhythmias, predictors for arrhythmias, and safety of exercise testing in children. A retrospective review of all patients ≤21 years undergoing exercise testing at our center from 2008 to 2012 was ...
Nordin Trevor C TC Department of Biological Sciences, Northern Arizona University, PO Box 5640, Flagstaff, AZ, 86011-5640, - - 2014
A single bout of acute exercise increases oxidative stress and stimulates a transient increase in antioxidant enzymes. We asked whether this response would induce protection from a subsequent oxidative challenge, different from that of exercise, and whether the effects were affected by aging. We compared young (20 ± 1 years, n = 8) and older ...
Davies N A - - 2014
ABSTRACT PPARγ is known to be activated via exercise-associated transient increases in oxidative stress. However, the precise mechanism(s) triggering PPARγ activation in monocytes during/following exercise remain to be confirmed. Here, two cohorts of five healthy male individuals undertook exercise bouts (cycling; 70%max; 45min) in the presence/absence of dietary antioxidant supplementation ...
Marques-Aleixo Inês I CIAFEL - Research Centre in Physical Activity, Health and Leisure, Faculty of Sport, University of Porto, Portugal. Electronic address: - - 2014
Doxorubicin (DOX) is an anti-cancer agent whose clinical usage results in a cumulative and dose-dependent cardiotoxicity. We have previously shown that exercise performed prior to DOX treatment reduces the resulting cardiac(mito) toxicity. We sought to determine the effects on cardiac mitochondrial toxicity of two distinct chronic exercise models (endurance treadmill ...
Duvall W Lane WL Division of Cardiology (Henry Low Heart Center), Hartford Hospital, South Building 2nd Floor, Hartford, CT, 06102, USA, - - 2014
Previous literature suggests that myocardial perfusion imaging (MPI) adds little to the prognosis of patients who exercise >10 metabolic equivalents (METs) during stress testing. With this in mind, we prospectively tested a provisional injection protocol in emergency department (ED) patients presenting for the evaluation of chest pain in which a ...
Bedno Sheryl S Department of Clinical Investigation, William Beaumont Army Medical Center, 5005 Piedras, El Paso, TX - - 2014
The aim of this study was to document risk factors for any injury and sports- and exercise-related injuries, including personal and occupational stress among active duty service members (SMs) in the Air Force, Army, Marine Corps, and Navy. A total of 10,692 SMs completed the April 2008 Status of Forces ...
Ploutz-Snyder Lori L 1 Exercise Physiology and Countermeasures, University Space Research Association , Houston, - - 2014
Abstract There is considerable variability among individuals in musculoskeletal response to long-duration spaceflight. The specific origin of the individual variability is unknown but is almost certainly influenced by the details of other mission conditions such as individual differences in exercise countermeasures, particularly intensity of exercise, dietary intake, medication use, stress, ...
Lindsay Angus A a School of Biological Sciences , University of Canterbury , Christchurch , New - - 2014
Abstract Rugby union is a sport governed by the impacts of high force and high frequency. Analysis of physiological markers following a game can provide an understanding of the physiological response of an individual and the time course changes in response to recovery. Urine and saliva were collected from 11 ...
Volpato Gustavo Tadeu GT Laboratory of Experimental Research on Gynecology and Obstetrics, Botucatu Medical School, Univ Estadual Paulista_Unesp, Botucatu, São Paulo, Brazil Laboratory of General Physiology and Reproductive Toxicology, Institute of Biological and Health Sciences, University Center of Araguaia, Federal University of Mato Grosso, Barra do Garças, Mato Grosso, Brazil - - 2014
The potential benefits and risks of physical exercise on fetal development during pregnancy remain unclear. The aim was to analyze maternal oxidative stress status and the placental morphometry to relate to intrauterine growth restriction (IUGR) from diabetic female rats submitted to swimming program after embryonic implantation. Pregnant Wistar rats were ...
Sharma Tripura T Discipline of Medicine, Sydney Medical School, University of Sydney, Sydney, Australia Dept of Cardiology, Royal Prince Alfred Hospital, Sydney, Australia Both authors contributed - - 2014
Right ventricular contractile response to pharmacological stress in pulmonary arterial hypertension (PAH) has not been characterised. We evaluated right ventricular contractile reserve in adults with PAH using dobutamine stress echocardiography. 16 PAH patients and 18 age-matched controls underwent low-dose dobutamine stress echocardiography. Contractile reserve was assessed by the change (Δ; ...
Dimitrow Pawel Petkow PP 2nd Department of Cardiology CMUJ, 31-501 Cracow, Poland. Electronic address: - - 2014
It has been proposed to use exercise stress echocardiography in the upright position with left ventricular outflow tract gradient monitoring both during and after exercise as a marker of genotype-positive/phenotype negative hypertrophic cardiomyopathy (HCM). Doppler measurement of gradient has been a very helpful and diagnostic examination in several subgroups of ...
Gerber Markus M 1 University of - - 2014
Summary.-This exploratory study was designed to compare four types of exercise activities in Swiss university students. A sample of 201 medical students (136 women, 65 men; M age = 23.2 yr., SD = 2.4) and 250 exercise and health sciences students (144 women, 106 men; M age = 22.3 yr., ...
Han Tae-Kyung TK School of Art and Physical Education, Andong University, Songcheon-dong, Andong-si, Gyeongsangbuk-do, 760-749, Republic of - - 2014
We assessed whether chronic treadmill exercise attenuated the depressive phenotype induced by restraint stress in ovariectomized mice (OVX). Immobility of OVX in the forced swimming test was comparable to that of sham mice (CON) regardless of the postoperative time. Immobility was also no difference between restrained mice (exposure to periodic ...
Zschucke Elisabeth E Jacobs Center on Lifelong Learning and Institutional Development, Jacobs University Bremen, Bremen, Germany; Department of Educational Sciences and Psychology, Freie Universität Berlin, Berlin, Germany; Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin, Charité Campus Mitte, Berlin, Germany. Electronic address: - - 2014
According to the cross-stressor adaptation hypothesis, physically trained individuals show lower physiological and psychological responses to stressors other than exercise, e.g. psychosocial stress. Reduced stress reactivity may constitute a mechanism of action for the beneficial effects of exercise in maintaining mental health. With regard to neural and psychoneuroendocrine stress responses, ...
Knapen Jan J Department of Rehabilitation Sciences, KU Leuven , Leuven , Belgium - - 2014
Abstract Purpose: to present clinical guidelines for exercise therapy in depressed patients derived from recent meta-analyses. Method: four meta-analyses on effects of physical exercise on mental and physical in depression were analysed. Results: For mild to moderate depression the effect of exercise may be comparable to antidepressant medication and psychotherapy; ...
Wang Jing J Institute of Vascular Medicine, Li Ka Shing Institute of Health Science, S.H. Ho Cardiovascular Disease and Stroke Centre, Division of Cardiology, Department of Medicine and Therapeutics, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong - - 2014
Although many prognostic variables have been reported, the risk stratification of patients with heart failure and preserved ejection fraction (HFPEF) has long been controversial due to considerable discordance. Ergometry stress echocardiography may provide a more clinical relevant evaluation in HFPEF. We aimed at evaluating the prognostic value of echocardiographic parameters ...
Haack Karla K V KK Department of Cellular and Integrative Physiology, University of Nebraska Medical Center, United - - 2014
The control of sympathetic outflow in the chronic heart failure (CHF) state is markedly abnormal. Patients with heart failure present with increased plasma norepinephrine and increased sympathetic nerve activity. The mechanism for this sympatho-excitation is multiple and varied. Both depression in negative feedback sensory control mechanisms and augmentation of excitatory ...
Corral Luisa L Intensive Care Unit and Neuropsychology Department, Bellvitge University Hospital, Barcelona, Spain Department of Physiological Sciences II, Pathology and Experimental Therapeutics and Physiology and Immunology of University of Barcelona, Barcelona, - - 2014
Circulating progenitor cells (CPC) treatments may have great potential for the recovery of neurons and brain function. To increase and maintain CPC with a program of exercise, muscle electro-stimulation (ME) and/or intermittent-hypobaric-hypoxia (IHH), and also to study the possible improvement in physical or psychological functioning of participants with Traumatic Brain ...
Li L L Department of Anesthesiology, Qilu Hospital, Shandong University, Jinan, Shandong, - - 2014
Obesity abolishes anesthetic pre-conditioning-induced cardioprotection due to impaired reactive oxygen species (ROS)-mediated adenosine monophosphate-activated protein kinase (AMPK) pathway, a consequence of increased basal myocardial oxidative stress. Exercise training has been shown to attenuate obesity-related oxidative stress. This study tests whether exercise training could normalize ROS-mediated AMPK pathway and prevent the ...
Hung Rupert K RK Johns Hopkins Ciccarone Center for the Prevention of Heart Disease, Baltimore, - - 2014
To examine the prognostic value of exercise capacity in patients with nonrevascularized and revascularized coronary artery disease (CAD) seen in routine clinical practice. We analyzed 9852 adults with known CAD (mean ± SD age, 61±12 years; 69% men [n=6836], 31% black race [n=3005]) from The Henry Ford ExercIse Testing (FIT) ...
Weiner Rory B RB Cardiovascular Performance Program, Cardiology Division, Massachusetts General Hospital, Yawkey Suite 5B 55 Fruit St. Boston, MA 02114, - - 2014
Exercise-induced cardiac remodeling (EICR) is the process by which the heart adapts to the physiologic stress of exercise. Non-invasive cardiovascular imaging has led to advances in the understanding of EICR, with sport-specific changes in left-ventricular (LV) structure and function being described; however, the majority of data stem from cross-sectional and ...
Boesch Maria M Clinical Psychology and Psychotherapy, University of Zurich, Zurich, - - 2014
Abstract The analysis of hair cortisol concentrations (HCC) is a promising new biomarker for retrospective measurement of chronic stress. The effect of basic military training (BMT) on chronic stress has not yet been reported. The aim of the present study was to investigate the effect of 10-week BMT on HCC, ...
Fonseca T R TR Departamento de Alimentos, Faculdade de Farmácia, Universidade Federal de Minas Gerais,Belo Horizonte, MG, Brasil - - - 2014
Physical exercise and soybean intake reduced oxidative stress and atherosclerosis. However, the associated effects of both interventions have not been yet investigated. Thus, we aimed to evaluate the combined effects of swimming exercise and soybean intake on lipid profile, oxidative stress and atherogenesis. Ten-week-old male Low-Density Lipoprotein Receptor Knockout mice ...
Ziolkowski Wieslaw - - 2014
ABSTRACT Exercise-induced changes in p66Shc-dependent signaling pathway are still not fully understood. The p66Shc protein is one of the key players in cell signaling, particularly in response to oxidative stress. Therefore, the aim of this study was to investigate the effect of prolonged swimming on the phosphorylation of p66Shc as ...
Jurczak I I Laboratory of Ergonomics and Exercise Physiology Medical University of Lodz, Lodz, Poland - - - 2014
It's known, controlled physical exercise which is a part of cardiac rehabilitation lead to positive changes in coronary circulation and contributes to minimizing other risk factors, such as lipid concentration in the blood or body weight as well as decreases the risk of another acute coronary disease. Monitoring cardiovascular activity ...
Sciolino N R NR Neuroscience Program, Biomedical and Health Sciences Institute, University of Georgia, Athens, GA 30602, USA. Electronic address: - - 2015
Exercise promotes resilience to stress and increases galanin in the locus coeruleus (LC), but the question of whether changes in galanin signaling mediate the stress-buffering effects of exercise has never been addressed. To test the contributions of galanin to stress resilience, male Sprague Dawley rats received intracerebroventricular (ICV) cannulation for ...
Conti Alberto A Emergency Medicine and Chest Pain Clinic, Department of Critical Care Medicine and Surgery, Careggi University Hospital, Florence, Italy. Electronic address: - - 2014
The novel exercise computer-assisted high-frequency QRS analysis (HF/QRS) has demonstrated improved sensitivity and specificity over the conventional ST/electrocardiogram-segment analysis (ST/ECG) in the detection of myocardial ischemia. The aim of the present study was to compare the diagnostic value of the validated exercise echocardiography (ex-Echo) with the novel exercise ECG (ex-ECG) ...
Tsou Yi-Hsien YH Department of Physiology, College of Medicine, National Cheng Kung University, Tainan, Taiwan, - - 2014
Exercise induces oxidative stress, which may activate adaptive antioxidant responses. Nuclear factor erythroid 2-related factor 2 (Nrf2) plays an important role in the defense of oxidative stress by regulating the expression of antioxidant enzymes, gamma-glutamylcysteine ligase (γGCL) and heme oxygenase-1 (HO-1). We investigated whether treadmill exercise protects dopaminergic neurons by ...
Sharman J E JE Menzies Research Institute Tasmania, University of Tasmania, Hobart, - - 2014
Blood pressure (BP) is a mandatory safety measure during graded intensity clinical exercise stress testing. While it is generally accepted that exercise hypotension is a poor prognostic sign linked to severe cardiac dysfunction, recent meta-analysis data also implicate excessive rises in submaximal exercise BP with adverse cardiovascular events and mortality, ...
Brugniaux Julien V JV Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Glamorgan, - - 2014
Elevated cardiorespiratory fitness improves resting cerebral perfusion, although to what extent this is further amplified during acute exposure to exercise stress and the corresponding implications for cerebral oxygenation remain unknown. To examine this, we recruited 12 moderately active and 12 sedentary healthy males. Middle cerebral artery blood velocity (MCAv) and ...
Booij Sanne H SH Interdisciplinary Center Psychopathology and Emotion Regulation, Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The - - 2014
The hypothalamic-pituitary-adrenal axis, autonomic nervous system, and immune system have been proposed to underlie the antidepressant effect of exercise. Using a population sample of 715 adolescents, we examined whether pathways from exercise to affective and somatic symptoms of depression were mediated by these putative mechanisms. Exercise (hours/week) and depressive symptoms ...
Cavkaytar S S Department of Obstetrics and Gynecology, Dr Zekai Tahir Burak Women's Health Research and Education Hospital , Ankara , - - 2014
The aim of this study was to assess the effects of home-based Kegel exercises in women with stress and mixed urinary incontinence. A total of 90 women with urodynamically proven urinary stress (SUI) and mixed (MUI) incontinence awaiting anti-incontinence surgery were recruited in the urogynaecology clinic of Ankara Zekai Tahir ...
Mellor Greg G Cardiovascular Sciences Research Centre, St. George's, University of London, London, United Kingdom - - 2014
-Sudden cardiac death (SCD) is a devastating event in the young. Referral to a specialist cardiac pathologist is recommended. Age, sex and circumstances of death may reflect underlying diagnoses. We aim to describe the demographics of victims and circumstances surrounding SCD with a normal heart (i.e. Sudden Arrhythmic Death Syndrome ...
Ho Rainbow Tin - - 2014
Patients with schizophrenia are characterized by high prevalence rates and chronicity that often leads to long-term institutionalization. Under the traditional medical model, treatment usually emphasizes the management of psychotic symptoms through medication, even though anti-psychotic drugs are associated with severe side effects, which can diminish patients' physical and psychological well-being. ...
Pearson Stephen John SJ Centre for Health, Sport and Rehabilitation Sciences Research, University of Salford, Manchester, M6 6PU, UK, - - 2014
It has traditionally been believed that resistance training can only induce muscle growth when the exercise intensity is greater than 65 % of the 1-repetition maximum (RM). However, more recently, the use of low-intensity resistance exercise with blood-flow restriction (BFR) has challenged this theory and consistently shown that hypertrophic adaptations can ...
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