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Peternelj Tina Tinkara TT Antioxidant Research Group, School of Human Movement Studies, The University of Queensland, St Lucia, Brisbane, QLD, 4072, Australia, - - 2014
Post-translational modification of intracellular proteins with O-linked β-N-acetylglucosamine (O-GlcNAc) profoundly affects protein structure, function, and metabolism. Although many skeletal muscle proteins are O-GlcNAcylated, the modification has not been extensively studied in this tissue, especially in the context of exercise. This study investigated the effects of glutathione depletion and acute exercise ...
Ciliberti P P Great Ormond Street Hospital for Children, London, WC1N 3JH, - - 2014
Although exercise stress echocardiography (ESE) is a well-validated technique in adult population, its use in children is quite limited. We aimed to assess the feasibility, the safety and the reproducibility of ESE, using on-line scanning in semi-supine cyclo-ergometer protocol in a large pediatric population. Between July 2008 and January 2013, ...
de Almeira Rodrigues Barbara B 1Laboratory of Molecular Biology of Exercise (LABMEX) and Center for Biological Assays (CEB), Center for Research in Sport Science (CEPECE), School of Applied Science, University of Campinas (UNICAMP), Limeira, São Paulo, Brazil; 2Laboratory of Exercise Biochemistry and Physiology, Health Science Unit, University of Extremo Sul Catarinense (UNESC), Criciúma, SC, Brazil; 3School of Physical Education and Sport of Ribeirão Preto, University of São Paulo (USP), Ribeirão Preto, São Paulo, Brazil; 4São Paulo University State (UNESP), Rio Claro, SP, - - 2014
To evaluate the effects of acute exercise on the TRB3 protein levels and interaction between TRB3/Akt proteins in the hypothalamus of obese rats. In addition, we evaluated the relationship between TRB3 and endoplasmic reticulum stress (ER stress) and verified whether an acute exercise session is able to influence these processes. ...
Slattery Katie K Sport and Exercise Discipline Group, Faculty of Health, University of Technology, Sydney, NSW, Australia, - - 2014
During periods of intensified physical training, reactive oxygen species (ROS) release may exceed the protective capacity of the antioxidant system and lead to dysregulation within the inflammatory and neuroendocrinological systems. Consequently, the efficacy of exogenous antioxidant supplementation to maintain the oxidative balance in states of exercise stress has been widely ...
Ryerson A Blythe AB Department of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, - - 2014
Surveillance for anthracycline cardiotoxicity in cancer survivors typically utilizes resting M-mode and two-dimensional echocardiography, which are insensitive to detection of subtle myocardial changes. We examined childhood cancer survivors treated with anthracyclines during exercise using various echocardiography techniques to investigate if these tools can better detect subclinical cardiac dysfunction. We recruited ...
Erdei Tamás T Wales Heart Research Institute, Cardiff University, Cardiff, - - 2014
Cardiac function should be assessed during stress in patients with suspected heart failure with preserved ejection fraction (HFPEF), but it is unclear how to define impaired diastolic reserve. We conducted a systematic review to identify which pathophysiological changes serve as appropriate targets for diagnostic imaging. We identified 38 studies of ...
Ghosh Reena M RM Division of Pediatric Cardiology, Department of Pediatrics, The Children's Hospital at Montefiore - Albert Einstein College of Medicine, 3415 Bainbridge Ave, Bronx, NY, 10467, - - 2014
Exercise testing is commonly performed in children for evaluation of cardiac disease. Few data exist, however, on the prevalence, types of arrhythmias, predictors for arrhythmias, and safety of exercise testing in children. A retrospective review of all patients ≤21 years undergoing exercise testing at our center from 2008 to 2012 was ...
Nordin Trevor C TC Department of Biological Sciences, Northern Arizona University, PO Box 5640, Flagstaff, AZ, 86011-5640, - - 2014
A single bout of acute exercise increases oxidative stress and stimulates a transient increase in antioxidant enzymes. We asked whether this response would induce protection from a subsequent oxidative challenge, different from that of exercise, and whether the effects were affected by aging. We compared young (20 ± 1 years, n = 8) and older ...
Davies N A - - 2014
ABSTRACT PPARγ is known to be activated via exercise-associated transient increases in oxidative stress. However, the precise mechanism(s) triggering PPARγ activation in monocytes during/following exercise remain to be confirmed. Here, two cohorts of five healthy male individuals undertook exercise bouts (cycling; 70%max; 45min) in the presence/absence of dietary antioxidant supplementation ...
Duvall W Lane WL Division of Cardiology (Henry Low Heart Center), Hartford Hospital, South Building 2nd Floor, Hartford, CT, 06102, USA, - - 2014
Previous literature suggests that myocardial perfusion imaging (MPI) adds little to the prognosis of patients who exercise >10 metabolic equivalents (METs) during stress testing. With this in mind, we prospectively tested a provisional injection protocol in emergency department (ED) patients presenting for the evaluation of chest pain in which a ...
Bedno Sheryl S Department of Clinical Investigation, William Beaumont Army Medical Center, 5005 Piedras, El Paso, TX - - 2014
The aim of this study was to document risk factors for any injury and sports- and exercise-related injuries, including personal and occupational stress among active duty service members (SMs) in the Air Force, Army, Marine Corps, and Navy. A total of 10,692 SMs completed the April 2008 Status of Forces ...
Ploutz-Snyder Lori L 1 Exercise Physiology and Countermeasures, University Space Research Association , Houston, - - 2014
Abstract There is considerable variability among individuals in musculoskeletal response to long-duration spaceflight. The specific origin of the individual variability is unknown but is almost certainly influenced by the details of other mission conditions such as individual differences in exercise countermeasures, particularly intensity of exercise, dietary intake, medication use, stress, ...
Lindsay Angus A a School of Biological Sciences , University of Canterbury , Christchurch , New - - 2014
Abstract Rugby union is a sport governed by the impacts of high force and high frequency. Analysis of physiological markers following a game can provide an understanding of the physiological response of an individual and the time course changes in response to recovery. Urine and saliva were collected from 11 ...
Volpato Gustavo Tadeu GT Laboratory of Experimental Research on Gynecology and Obstetrics, Botucatu Medical School, Univ Estadual Paulista_Unesp, Botucatu, São Paulo, Brazil Laboratory of General Physiology and Reproductive Toxicology, Institute of Biological and Health Sciences, University Center of Araguaia, Federal University of Mato Grosso, Barra do Garças, Mato Grosso, Brazil - - 2014
The potential benefits and risks of physical exercise on fetal development during pregnancy remain unclear. The aim was to analyze maternal oxidative stress status and the placental morphometry to relate to intrauterine growth restriction (IUGR) from diabetic female rats submitted to swimming program after embryonic implantation. Pregnant Wistar rats were ...
Sharma Tripura T Discipline of Medicine, Sydney Medical School, University of Sydney, Sydney, Australia Dept of Cardiology, Royal Prince Alfred Hospital, Sydney, Australia Both authors contributed - - 2014
Right ventricular contractile response to pharmacological stress in pulmonary arterial hypertension (PAH) has not been characterised. We evaluated right ventricular contractile reserve in adults with PAH using dobutamine stress echocardiography. 16 PAH patients and 18 age-matched controls underwent low-dose dobutamine stress echocardiography. Contractile reserve was assessed by the change (Δ; ...
Gerber Markus M 1 University of - - 2014
Summary.-This exploratory study was designed to compare four types of exercise activities in Swiss university students. A sample of 201 medical students (136 women, 65 men; M age = 23.2 yr., SD = 2.4) and 250 exercise and health sciences students (144 women, 106 men; M age = 22.3 yr., ...
Han Tae-Kyung TK School of Art and Physical Education, Andong University, Songcheon-dong, Andong-si, Gyeongsangbuk-do, 760-749, Republic of - - 2014
We assessed whether chronic treadmill exercise attenuated the depressive phenotype induced by restraint stress in ovariectomized mice (OVX). Immobility of OVX in the forced swimming test was comparable to that of sham mice (CON) regardless of the postoperative time. Immobility was also no difference between restrained mice (exposure to periodic ...
Knapen Jan J Department of Rehabilitation Sciences, KU Leuven , Leuven , Belgium - - 2014
Abstract Purpose: to present clinical guidelines for exercise therapy in depressed patients derived from recent meta-analyses. Method: four meta-analyses on effects of physical exercise on mental and physical in depression were analysed. Results: For mild to moderate depression the effect of exercise may be comparable to antidepressant medication and psychotherapy; ...
Corral Luisa L Intensive Care Unit and Neuropsychology Department, Bellvitge University Hospital, Barcelona, Spain Department of Physiological Sciences II, Pathology and Experimental Therapeutics and Physiology and Immunology of University of Barcelona, Barcelona, - - 2014
Circulating progenitor cells (CPC) treatments may have great potential for the recovery of neurons and brain function. To increase and maintain CPC with a program of exercise, muscle electro-stimulation (ME) and/or intermittent-hypobaric-hypoxia (IHH), and also to study the possible improvement in physical or psychological functioning of participants with Traumatic Brain ...
Li L L Department of Anesthesiology, Qilu Hospital, Shandong University, Jinan, Shandong, - - 2014
Obesity abolishes anesthetic pre-conditioning-induced cardioprotection due to impaired reactive oxygen species (ROS)-mediated adenosine monophosphate-activated protein kinase (AMPK) pathway, a consequence of increased basal myocardial oxidative stress. Exercise training has been shown to attenuate obesity-related oxidative stress. This study tests whether exercise training could normalize ROS-mediated AMPK pathway and prevent the ...
Weiner Rory B RB Cardiovascular Performance Program, Cardiology Division, Massachusetts General Hospital, Yawkey Suite 5B 55 Fruit St. Boston, MA 02114, - - 2014
Exercise-induced cardiac remodeling (EICR) is the process by which the heart adapts to the physiologic stress of exercise. Non-invasive cardiovascular imaging has led to advances in the understanding of EICR, with sport-specific changes in left-ventricular (LV) structure and function being described; however, the majority of data stem from cross-sectional and ...
Boesch Maria M Clinical Psychology and Psychotherapy, University of Zurich, Zurich, - - 2014
Abstract The analysis of hair cortisol concentrations (HCC) is a promising new biomarker for retrospective measurement of chronic stress. The effect of basic military training (BMT) on chronic stress has not yet been reported. The aim of the present study was to investigate the effect of 10-week BMT on HCC, ...
Fonseca T R TR Departamento de Alimentos, Faculdade de Farmácia, Universidade Federal de Minas Gerais,Belo Horizonte, MG, Brasil - - - 2014
Physical exercise and soybean intake reduced oxidative stress and atherosclerosis. However, the associated effects of both interventions have not been yet investigated. Thus, we aimed to evaluate the combined effects of swimming exercise and soybean intake on lipid profile, oxidative stress and atherogenesis. Ten-week-old male Low-Density Lipoprotein Receptor Knockout mice ...
Ziolkowski Wieslaw - - 2014
ABSTRACT Exercise-induced changes in p66Shc-dependent signaling pathway are still not fully understood. The p66Shc protein is one of the key players in cell signaling, particularly in response to oxidative stress. Therefore, the aim of this study was to investigate the effect of prolonged swimming on the phosphorylation of p66Shc as ...
Jurczak I I Laboratory of Ergonomics and Exercise Physiology Medical University of Lodz, Lodz, Poland - - - 2014
It's known, controlled physical exercise which is a part of cardiac rehabilitation lead to positive changes in coronary circulation and contributes to minimizing other risk factors, such as lipid concentration in the blood or body weight as well as decreases the risk of another acute coronary disease. Monitoring cardiovascular activity ...
Sciolino N R NR Neuroscience, Biomedical and Health Sciences Institute, University of Georgia, Athens, GA 30602 USA. Electronic address: - - 2014
Exercise promotes resilience to stress and increases galanin in the locus coeruleus (LC), but the question of whether changes in galanin signaling mediate the stress-buffering effects of exercise has never been addressed. To test the contributions of galanin to stress resilience, male Sprague Dawley rats received intracerebroventricular (ICV) cannulation for ...
Tsou Yi-Hsien YH Department of Physiology, College of Medicine, National Cheng Kung University, Tainan, Taiwan, - - 2014
Exercise induces oxidative stress, which may activate adaptive antioxidant responses. Nuclear factor erythroid 2-related factor 2 (Nrf2) plays an important role in the defense of oxidative stress by regulating the expression of antioxidant enzymes, gamma-glutamylcysteine ligase (γGCL) and heme oxygenase-1 (HO-1). We investigated whether treadmill exercise protects dopaminergic neurons by ...
Sharman J E JE Menzies Research Institute Tasmania, University of Tasmania, Hobart, - - 2014
Blood pressure (BP) is a mandatory safety measure during graded intensity clinical exercise stress testing. While it is generally accepted that exercise hypotension is a poor prognostic sign linked to severe cardiac dysfunction, recent meta-analysis data also implicate excessive rises in submaximal exercise BP with adverse cardiovascular events and mortality, ...
Brugniaux Julien V JV Neurovascular Research Laboratory, Faculty of Life Sciences and Education, University of South Wales, Glamorgan, - - 2014
Elevated cardiorespiratory fitness improves resting cerebral perfusion, although to what extent this is further amplified during acute exposure to exercise stress and the corresponding implications for cerebral oxygenation remain unknown. To examine this, we recruited 12 moderately active and 12 sedentary healthy males. Middle cerebral artery blood velocity (MCAv) and ...
Booij Sanne H SH Interdisciplinary Center Psychopathology and Emotion Regulation, Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The - - 2014
The hypothalamic-pituitary-adrenal axis, autonomic nervous system, and immune system have been proposed to underlie the antidepressant effect of exercise. Using a population sample of 715 adolescents, we examined whether pathways from exercise to affective and somatic symptoms of depression were mediated by these putative mechanisms. Exercise (hours/week) and depressive symptoms ...
Cavkaytar S S Department of Obstetrics and Gynecology, Dr Zekai Tahir Burak Women's Health Research and Education Hospital , Ankara , - - 2014
The aim of this study was to assess the effects of home-based Kegel exercises in women with stress and mixed urinary incontinence. A total of 90 women with urodynamically proven urinary stress (SUI) and mixed (MUI) incontinence awaiting anti-incontinence surgery were recruited in the urogynaecology clinic of Ankara Zekai Tahir ...
Mellor Greg G Cardiovascular Sciences Research Centre, St. George's, University of London, London, United Kingdom - - 2014
-Sudden cardiac death (SCD) is a devastating event in the young. Referral to a specialist cardiac pathologist is recommended. Age, sex and circumstances of death may reflect underlying diagnoses. We aim to describe the demographics of victims and circumstances surrounding SCD with a normal heart (i.e. Sudden Arrhythmic Death Syndrome ...
Ho Rainbow Tin - - 2014
Patients with schizophrenia are characterized by high prevalence rates and chronicity that often leads to long-term institutionalization. Under the traditional medical model, treatment usually emphasizes the management of psychotic symptoms through medication, even though anti-psychotic drugs are associated with severe side effects, which can diminish patients' physical and psychological well-being. ...
Pearson Stephen John SJ Centre for Health, Sport and Rehabilitation Sciences Research, University of Salford, Manchester, M6 6PU, UK, - - 2014
It has traditionally been believed that resistance training can only induce muscle growth when the exercise intensity is greater than 65 % of the 1-repetition maximum (RM). However, more recently, the use of low-intensity resistance exercise with blood-flow restriction (BFR) has challenged this theory and consistently shown that hypertrophic adaptations can ...
Diverio S S 1Laboratory of Ethology and Animal Welfare (LEBA),Department of Veterinary Medicine,via San Costanzo 4,0126 - - 2014
Exercise has been shown to increase mRNA expression of a growing number of genes. The aim of this study was to assess if mRNA expression of the metabolism- and oxidative stress-related genes GLUT4 (glucose transporter 4), COX2 (cyclooxygenase 2), SOD1 (superoxide dismutase 1) and HSP70 (heat shock protein 70) in ...
Ait-Ali Lamia L Institute of Clinical Physiology, CNR, Massa-Pisa, Italy. Electronic address: - - 2014
Patients with repaired tetralogy of Fallot often present residual hemodynamic abnormalities leading to right ventricular (RV) burden. Semisupine exercise echocardiography (Ex-Echo) is a validated method for diagnosis and prognosis in ischemic and valvular heart diseases and has potential for the evaluation of RV burden, pressure, and function. The aims of ...
Nichols Andrew W AW Family Medicine and Community Health, John A. Burns School of Medicine, University of Hawaii at Mānoa, University Health Services Mānoa, 1710 East-West Road, Honolulu, HI, 96822, USA, - - 2014
Exertional heat-related illness (EHRI) is comprised of several states that afflict physically active persons when exercising during conditions of high environmental heat stress. Certain forms of EHRI may become life threatening if not treated. Exertional heat stroke (EHS), characterized by a core body temperature of >40 ° C and mental status ...
Kuru Pinar P Marmara University School of Medicine, Istanbul, - - 2014
Physical activity has been found to be related with many health benefits. Our aim was to investigate the effect of chronic moderate exercise from acute stress on nicotine and cigarette smoke exposed rats. Male Sprague Dawley rats (200-250 g, n=48) were divided into 6 groups as non-exercised, exercised, smoke exposed, ...
Ross Amanda J AJ Penn State College of - - 2014
Patients with coronary artery disease have attenuated coronary vasodilator responses to physiological stress, which is partially attributed to a β-adrenergic receptor (βAR) mediated mechanism. Whether βARs contribute to impaired coronary vasodilation seen with healthy aging is unknown. The purpose of this study was to investigate the role of βARs in ...
Mut Fernando F Department of Nuclear Medicine, Spanish Association Hospital, Montevideo, - - 2014
Transient post-ischemic LV dysfunction due to myocardial stunning in patients with coronary artery disease can be missed by conventional gated SPECT (GSPECT) acquisitions. The aim of this IAEA-sponsored multi-center study was to determine whether early post-exercise imaging is more likely to detect stunning than conventional without adversely affecting image quality ...
Watson Kurt K Department of Neurobiology, Physiology, and Behavior, University of California Davis, United - - 2014
Exercise is the greatest physiological stress that our bodies experience. For example, during maximal endurance exercise in elite athlete's cardiac output can increase up to 8-fold and the working muscles receive 21-times more blood each minute than at rest. Given the physiological stress associated with exercise and the adaptations that ...
Lord Rachel R Research Institute for Sport and Exercise Sciences, Tom Reilly Building, Liverpool John Moores University, Byrom Street, Liverpool, L3 3AF, UK, - - 2014
There is contradictory evidence related to the impact of ultra-marathon running on right ventricular (RV) structure and function. Consequently, the aims of this study were to: (1) comprehensively assess RV structure and function before and immediately following a 100-mile ultra-marathon in highly trained runners, (2) determine the nature of RV ...
Mas-Stachurska Aleksandra A Servicio de Cardiología, Instituto Clínico del Tórax, Hospital Clínic, IDIBAPS, Universidad de Barcelona, Barcelona, - - 2014
Up to 4% of patients with acute chest pain, normal electrocardiogram, and negative troponins present major adverse cardiac events as a result of undiagnosed acute coronary syndrome. Our aim was to compare the diagnostic performance of multidetector computed tomography and exercise echocardiography in patients with a low-to-intermediate probability of coronary ...
Mas-Stachurska Aleksandra A Servicio de Cardiología, Instituto Clínico del Tórax, Hospital Clínic, IDIBAPS, Universidad de Barcelona, Barcelona, - - 2014
Up to 4% of patients with acute chest pain, normal electrocardiogram, and negative troponins present major adverse cardiac events as a result of undiagnosed acute coronary syndrome. Our aim was to compare the diagnostic performance of multidetector computed tomography and exercise echocardiography in patients with a low-to-intermediate probability of coronary ...
Krzeszowiak Jakub J Department of Hygiene, Medical University, Wroclaw, - - 2014
Background. The stimuli acting on a person in a high mountain environment (such as hypobaric hypoxia with subsequent reoxygenation, physical exercise) can significantly increase oxidative stress, stimulate erythropoiesis, lead to changes in the blood count and participate in the development of altitude sickness. Objective. The aim was to investigate changes ...
Ghaderi Fariba F Department of Physiotherapy, Faculty of Rehabilitation, Tabriz University of Medical Sciences, - - 2014
[Purpose] This review article is designed to expose physiotherapists to a physiotherapy assessment of stress urinary incontinence (SUI) and the treatment and possibly preventive roles that they might play for women with SUI. Specifically, the goal of this article is to provide an understanding of pelvic floor muscle function and ...
Miliaresis Christa C Department of Pediatrics, Division of Pediatric Cardiology, New York Medical College/Maria Fareri Childrens Hospital, Valhalla, - - 2014
Cardiopulmonary exercise stress testing (CPET) is a vital tool used to assess patients with a history of congenital heart disease. There are several tests in the cardiologist's armamentarium that allow for assessment of cardiac anatomy and function. The majority of these tests are only performed with the body at rest ...
Dorfs Stephan S Klinik für Kardiologie und Angiologie II, Universitäts-Herzzentrum Freiburg • Bad Krozingen, Südring 15, Bad Krozingen 79189, Germany - - 2014
In patients with suspected heart failure with preserved ejection fraction (HFpEF), invasive exercise testing may be considered when measurements at rest are inconclusive. However, the prognostic impact of invasive exercise testing is uncertain, so far. We retrospectively analysed mortality in 355 patients [mean age 61.2 ± 11.3 years, 235 (66.2%) ...
Barlow Paul A PA Menzies Research Institute Tasmania, University of Tasmania, Medical Science 1 Building, Liverpool Street, Hobart 7000, Tasmania, Australia; School of Human Life Sciences, University of Tasmania, Launceston, Tasmania, - - 2014
The independent prognostic significance of abnormally low systolic blood pressure (SBP) during exercise stress testing (LowExBP) across different clinical and exercise conditions is unknown. We sought by systematic review and meta-analysis to determine the association between cardiovascular/all-cause outcomes and LowExBP across different patient clinical presentations, exercise modes, exercise intensities and ...
Tajiri Kimiko K Department of Nursing, School of Health Sciences, Bukkyo University, - - 2014
[Purpose] The purpose of this study was to devise a new urinary incontinence exercise using co-contraction of both the transverse abdominal muscle (TA) and pelvic floor muscle (PFM) and examine the intervention effect in middle-aged women with stress urinary incontinence (SUI). [Subjects] The subjects were fifteen women with SUI who ...
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