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Reuss Christina S - - 2005
Doppler tissue imaging variables were measured in 18 healthy men and women during supine bicycle stress exercise and upright exercise treadmill testing. From a color Doppler tissue imaging cineloop, tissue velocities in basal and mid segments of the standard 3 apical views during rest and peak exercise were assessed. Compared ...
Tanaka Hirokazu - - 2005
BACKGROUND: Exercise gated single-photon emission computed tomography (SPECT) using technetium-99m (99mTc)-sestamibi evaluates both myocardial perfusion during stress and wall motion >30 min after the stress, which has the potential to assess not only exercise-induced myocardial ischemia but also the development of myocardial stunning. METHODS AND RESULTS: To evaluate the incidence ...
Leitman Marina - - 2006
To compare non-invasive determination of cardiac index (CI) by whole body electrical bioimpedance using the NICaS apparatus and Doppler echocardiography, and the role of cardiac power index (Cpi) and total peripheral resistance index (TPRi) calculation during dobutamine stress echocardiography (DSE). We enrolled 60 consecutive patients undergoing DSE. Patients were prospectively ...
Dilsizian Vasken - - 2005
BACKGROUND: After myocardial ischemia, prolonged suppression of fatty acid metabolism may persist despite restoration of blood flow, which is called metabolic stunning. We hypothesized that a branched-chain fatty acid, beta-methyl-p-[(123)I]-iodophenyl-pentadecanoic acid (BMIPP), might identify the presence of myocardial ischemia late after demand ischemia at rest up to 30 hours later. ...
Naum Alexandru - - 2005
PURPOSE: Patient motion during dynamic PET studies is a well-documented source of errors. The purpose of this study was to investigate the incidence of frame-to-frame motion in dynamic ( 15)O-water myocardial perfusion PET studies, to test the efficacy of motion correction methods and to study whether implementation of motion correction ...
Heo Jaekyeong - - 2005
BACKGROUND: Prior studies with first-pass radionuclide angiography (RNA) during treadmill exercise used a single-crystal (Anger) or multicrystal gamma camera and technetium 99m tracers. Motion correction, when done, used point sources, which limited correction to only plane movement. METHODS AND RESULTS: We examined the performance of a multiwire gamma camera (MWGC), ...
Slater D N - - 2005
OBJECTIVE: This study assesses the accuracy of published quantitative and qualitative criteria in the Bethesda System (TBS) for squamous intra-epithelial lesions. METHODS: Quantitative image analysis was undertaken on illustrations from TBS publications and also from slides in Cytology Training Centre teaching sets. Comparisons were also made with the British Society ...
Jeong Hwan Jeong - - 2005
The purpose of this volunteer study was to investigate whether pretreatment with UDCA before the administration of (99m)Tc DISIDA affects the biliary excretion of the DISIDA, and whether it can shorten the total imaging time. Ten young, healthy volunteers (eight males, two females, mean age: 26.3 +/- 2.1 years) participated ...
Pierre-Justin Gilbert - - 2005
BACKGROUND: Evaluation and quantification of regional myocardial function remain a challenge for imaging techniques in stress test. Strain and strain rate can be calculated from velocity gradients in time and space. This new technique has been developed to allow quantifiable stress echocardiography. The aim of this study was to define ...
Schwarz Tobias - - 2005
An 8-year-old sexually intact male Golden Retriever with a history of collapse during exercise underwent an examination during which tachydysrhythmia was identified. At another institution, a 12.5-year-old spayed female Lhasa Apso was referred because of a cough and for evaluation of a heart murmur. In the Golden Retriever, radiographic examination ...
Gunn Rebekah G - - 2005
Alterations in an individual analyte rarely provide an indication of the initiating circumstances that caused the abnormality. It is obvious from the previous discussion that multiple organs or organ systems can cause abnormal results in the same analyte. This fact underscores the importance of evaluating a biochemical profile in an ...
Chow Benjamin J W - - 2005
OBJECTIVES: This study assessed the feasibility of treadmill exercise rubidium-82 ((82)Rb) positron emission tomography (PET) and compared image quality and diagnostic content with dipyridamole (82)Rb PET in patients referred for evaluation of coronary artery disease (CAD). BACKGROUND: Dipyridamole stress (82)Rb PET myocardial perfusion imaging (MPI) is an accurate imaging modality ...
Riksen Niels P - - 2005
The pressor response to exercise is of great importance in both physiology and pathophysiology. Whether endogenous adenosine is a trigger for this reflex remains controversial. Muscle interstitial adenosine concentration can be determined by microdialysis. However, there are indications that local muscle cell damage by the microdialysis probe confounds these measurements ...
Akutsu Yasushi - - 2005
BACKGROUND: The aim of this study was to evaluate the relationship between exercise-induced QT dispersion and condition of infarct-related myocardium including myocardial scar after angioplasty assessed with exercise perfusion single photon emission computed tomography (SPECT). METHODS: Exercise thallium-201 SPECT was performed 6 months after successful direct angioplasty in 67 male ...
Jaffe Tracy A - - 2005
OBJECTIVE: Our objective was to evaluate the role of Valsalva's maneuver during MDCT for the diagnosis and characterization of abdominal wall hernias. SUBJECTS AND METHODS: From September 2002 to May 2003, 100 consecutive patients (37 men and 63 women; mean age, 53 years) with suspected anterior abdominal wall hernias underwent ...
Scherhag A - - 2005
Stress echocardiography (SE) has become a widely accepted clinical tool for the non-invasive diagnosis of coronary artery disease (CAD). Previous studies have confirmed that SE has superior diagnostic value compared to exercise ECG testing. SE has also emerged as a cost-effective alternative to nuclear imaging techniques in patients where symptoms ...
Aktaş Ayşe - - 2005
BACKGROUND AND AIM: During recovery after exercise, the heart rate and blood pressure return to a resting state more rapidly than the end-systolic left ventricular dimensions and fractional shortening. The aim of this study was to assess how exercise-related cardiac changes affect the interpretation of myocardial perfusion images in normal ...
Kamínek Milan - - 2005
The second survey of nuclear cardiology in the Czech Republic was conducted to ascertain whether the activity had increased since the first survey in 2001; we also intended to identify new trends in clinical practice. All 46 departments of nuclear medicine in the Czech Republic completed a questionnaire concerning nuclear ...
Cavusoglu Yuksel - - 2005
BACKGROUND: Cardiac syndrome X is defined as angina-like chest pain with transient ischemic ST-segment changes during exercise and angiographically normal epicardial coronary arteries. Studies with myocardial perfusion imaging in this syndrome have indicated that some patients, but not all, have an abnormality on perfusion scan. However, the impact of these ...
Tehranipour Neda - - 2005
Combining exercise and adenosine during the stress phase of myocardial perfusion imaging (MPI) is known to reduce adverse effects and improve image quality. The aim of this study was to assess whether it can also improve the automatic calculation of left ventricular ejection fraction (LVEF) by QGS software package, during ...
Liao Lawrence - - 2005
Radionuclide exercise testing provides prognostic information in patients with known or suspected coronary artery disease (CAD). The relative contribution of 3 noninvasive tests--the Duke treadmill score (DTS), first-pass radionuclide angiography with calculation of the ejection fraction (RNA-EF), and perfusion SPECT--has not been comparatively assessed in a high-risk population undergoing all ...
Laake K O - - 2004
BACKGROUND: Pouchitis is a common and troublesome condition in patients operated on with ileal-pouch-anal-anastomosis (IPAA). A disturbed mucosal perfusion in the pouch has been suggested as a possible cause. Laser Doppler flowmetry (LDF) has been used successfully to measure gastric and colonic mucosal perfusion in humans. In a previous study, ...
Toba Masahiro - - 2004
BACKGROUND: This study determines the value of gated single photon emission computed tomography (SPECT) imaging soon after exercise to identify patients with single-vessel disease and exercise-induced prolonged myocardial dysfunction (ie, postischemic stunning). METHODS AND RESULTS: We examined 19 normal individuals and 52 patients with single-vessel disease by use of 2-day ...
Sand Niels Peter Rønnow - - 2004
Tracers for myocardial perfusion imaging during stress should not only have high cardiac uptake but they should also have a fast blood clearance to prevent myocardial tracer uptake after the ischaemic stimulus. The present study characterize the early phase of the arterial (99m)Tc-sestamibi (MIBI) time-activity curve after venous bolus injection ...
Scott James A - - 2004
AIM: To establish proof of the principle that a computer-based neural network method can be employed that will enhance diagnostic accuracy vis-a-vis image analysis alone in the interpretation of treadmill exercise tests performed in conjunction with myocardial perfusion imaging. MATERIALS AND METHODS: One-hundred-and-two patients underwent myocardial perfusion imaging in association ...
Gerhard Alexander A MRC Clinical Sciences Center and Division of Neuroscience, Faculty of Medicine, Imperial College, London, United Kingdom. - - 2004
Corticobasal degeneration (CBD) is a neurodegenerative parkinsonian disorder of unknown cause that shows considerable clinical heterogeneity. In CBD, activated microglia have been shown to be associated closely with the extensive tau pathology found in the affected basal ganglia, brainstem nuclei, and cortical regions. We report on the use of [(11)C](R)-(1-[2-chlorophenyl]-N-methyl-N-[1-methylpropyl]-3-isoquinoline ...
Lapeyre André C AC - - 2004
One hundred eight patients with single- or dual-chamber pacemakers underwent exercise myocardial perfusion imaging with thallium-201 or technetium-99m sestamibi. A high-risk scan (a large fixed defect, a large reversible defect, or evidence of cardiomyopathy) identified patients at high risk for cardiac death on both a univariate and multivariate basis.
Perin Emerson C - - 2004
BACKGROUND: We recently reported the safety and feasibility of autologous bone marrow mononuclear cell (ABMMNC) injection into areas of ischemic myocardium in patients with end-stage ischemic cardiomyopathy. The present study evaluated the safety and efficacy of this therapy at 6- and 12-month follow-up. METHODS AND RESULTS: Twenty patients with 6- ...
Thomas Gregory S - - 2004
Concomitant low-level treadmill exercise with adenosine pharmacologic stress (AdenoEx) during radionuclide myocardial perfusion imaging has become commonly used in recent years, particularly in large-volume laboratories. A number of studies have demonstrated a beneficial impact of AdenoEx protocols. These benefits include decreased side effects, improved safety and patient tolerance, improved target-to-background ...
Coan A C - - 2004
Mesial temporal lobe epilepsy (MTLE) is associated with hippocampal atrophy and hippocampal signal abnormalities. In our series of familial MTLE (FMTLE), we found a high proportion of hippocampal abnormalities. To quantify signal abnormalities in patients with FMTLE we studied 152 individuals (46 of them asymptomatic) with FMTLE. We used NIH-Image ...
Kim Hyung-Kwan - - 2004
Recently, it has become possible to measure coronary flow reserve (CFR) non-invasively with transthoracic echocardiography (TTE). Twenty-one hypertrophic cardiomyopathy (HCMP) patients with asymmetric septal hypertrophy who had either not started medication or had stopped medication for at least 24 h were enrolled, along with 29 normal subjects. Mean diastolic coronary ...
Graff-Guerrero A - - 2004
OBJECTIVE: This study was performed to evaluate the acute effect of a single repetitive transcranial magnetic stimulation (rTMS) session in a focal hyperperfusion epileptogenic region to induce a transitory decrease of epileptiform activity. CASE REPORT: Two epilepsia partialis continua (EPC)-diagnosed patients, received one session with 15 trains of rTMS (20 ...
Nettleton Jo S - - 2004
This study concerns the testicular uptake and dosimetry of Auger electron-emitting radionuclides that are used during routine diagnostic nuclear medicine procedures. To consider the possible effects of these radionuclides on spermatogenic cells, a study has been undertaken to obtain in vivo data for quantification of (111)In chloride and (201)Tl chloride ...
Rinne J O - - 2004
OBJECTIVE: To investigate dopamine reuptake sites (dopamine transporter) in the caudate nucleus and putamen in narcolepsy. PATIENTS AND METHODS: Ten patients with narcolepsy and 15 controls were studied with positron emission tomography. A cocaine analogue [11C]-CFT was used as a radioligand. RESULTS: The uptake of[11C]-CFT was within normal limits (89% ...
Kusunoki Kanji - - 2004
This study reports an evaluation of coronary arterial blood flow patterns in patients with diabetes mellitus and healthy subjects using magnetic resonance coronary angiography (MRCA). Twenty patients with diabetes mellitus (DM group) and 20 healthy subjects (N group) were studied using MRCA and myocardial SPECT images using (99m)Tc-tetrofosmin (TF). The ...
Charvat J - - 2004
BACKGROUND: Diabetes mellitus is known to be a risk factor of the coronary heart disease even in the asymptomatic patients. Only a limited number of reports comparing the significance of different noninvasive stress tests in establishing the diagnosis of the advanced coronary lesions exists. OBJECTIVES: The aim of the study ...
Shry Eric A - - 2003
BACKGROUND: Exercise treadmill testing has limited sensitivity for the detection of coronary artery disease, frequently requiring the addition of imaging modalities to enhance the predictive value of the test. Recently, there has been interest in using nonstandard electrocardiographic (ECG) leads during exercise testing. METHODS:We consecutively enrolled all patients undergoing exercise ...
Barrington S F - - 2004
The detection of hibernating myocardium is important because revascularisation results in improved function and prognosis in patients with hibernation but not in those with non-viable myocardium. The primary aim of this study was to compare the diagnostic accuracy of four techniques with respect to hibernation in the same study population ...
Ances B M - - 2003
This pilot study investigated the effect of menstrual cycle phase (late luteal and mid-follicular) on cerebral perfusion changes during photic stimulation in both controls (n = 5) and true menstrual migraine patients (n = 5). No significant differences in resting baseline perfusion were observed between the two groups during either ...
Ceravolo R - - 2003
The clinical differentiation of Lewy body dementia (LBD) from Alzheimer's disease (AD) may be difficult. The aim of the present study was to assess the dopamine transporter function and the perfusional pattern in LBD and AD in vivo. Twenty patients with probable LBD and 24 with probable AD underwent on ...
Hsu H B - - 2004
Patients with systemic lupus erythematosus (SLE) may develop premature atherosclerosis, notably peripheral vascular disease presenting with intermittent claudication or gangrene. This study evaluates the usefulness of thallium-201 muscle perfusion scan (Tl-201 muscle scan) for investigating perfusion reserve in the lower limbs of 25 asymptomatic, female SLE patients without peripheral ischemia ...
Marwick T H - - 2003
BACKGROUND: Patients with known or suspected coronary disease are often investigated to facilitate risk assessment. We sought to examine the cost-effectiveness of strategies based on exercise echocardiography and exercise electrocardiography. METHODS AND RESULTS: We studied 7656 patients undergoing exercise testing; of whom half underwent exercise echocardiography. Risk was defined with ...
Holly Thomas A - - 2003
BACKGROUND: Failure to achieve an adequate heart rate limits the sensitivity of exercise myocardial perfusion imaging (MPI) for the detection of coronary artery disease. In addition, it is often not possible to discontinue medications that may blunt the heart rate response to exercise, because of conditions such as hypertension or ...
Cortigiani Lauro - - 2003
Exercise electrocardiography (ECG) is of limited usefulness in hypertensive patients, whereas pharmacologic stress echocardiography can provide diagnostic and prognostic information. The aim of this study was to compare the prognostic value of clinical data, exercise ECG, and pharmacologic stress echocardiography in hypertensive patients with chest pain and to identify the ...
Kim Kyeong Min - - 2003
Correction of scatter and attenuation is essential for quantitative SPECT. In this work, we evaluated the accuracy gained from a method of transmission-dependent convolution subtraction (TDCS) in the quantitation of activity that is highly concentrated in the striatum (STR). METHODS: SPECT data were acquired from an (123)I-containing phantom with a ...
Dori G - - 2003
When chest symptoms recur in a patient who underwent percutaneous transluminal coronary angioplasty (PTCA), it is necessary to rule out restenosis (R). Three main noninvasive tests suggest the presence of R: exercise stress test (XT), myocardial perfusion imaging (MPI) and stress echocardiography (s-echo). The objectives of this review were: (1) ...
Agarwal Harish C - - 2003
PURPOSE: To study the characteristics of the optic nerve head using a scanning laser ophthalmoscope, the Heidelberg Retina Tomograph II (HRT II), in a normal population and to determine the specificity of HRT II diagnostic indices in the study population. METHODS: The optic nerve heads from 275 consecutive, randomly selected ...
Lapeyre André C AC - - 2003
BACKGROUND: Exercise thallium-201 imaging provides a noninvasive estimate of the amount of myocardium presumed to be at risk of infarcting should a complete occlusion of the coronary stenosis occur. The relationship between the size of the exercise thallium perfusion defect and the extent of myocardium supplied by a diseased coronary ...
Hrynchak Patricia - - 2003
The cup-to-disc (CD) ratio evaluated using stereoscopic biomicroscopy was compared with that evaluated by viewing a non-stereo digital image of the optic nerve head. Twenty normal subjects (mean age 26 +/- 4 years) were evaluated by two observers. The average CD ratio was 0.29 with a range of 0-0.80. The ...
Taniguchi Masayuki - - 2003
OBJECTIVE: The purpose of this study was to evaluate the prognostic and clinical significance of newly acquired complete right bundle branch block (CRBBB) in airline pilots. PATIENTS: This study included pilots with acquired CRBBB, identified from a group of over 2,700 Japan Airline pilots. When the pilots applied for employment, ...
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