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Takase Bonpei - - 2009
OBJECTIVE: The electrocardiographic index of QT dispersion (QTd) is related to the occurrence of arrhythmia. In patients with suspected or known coronary artery disease, QTd may be affected by exercise. We investigated whether QTd that is automatically calculated by a newly developed computer system could be used as a marker ...
Bouzas-Mosquera Alberto - - 2009
OBJECTIVES: We sought to assess the value of exercise echocardiography (EE) for predicting outcome in patients with known or suspected coronary artery disease and normal exercise electrocardiogram (ECG) testing. BACKGROUND: The prognostic value of EE in patients with normal exercise ECG testing has not been characterized. METHODS: We studied 4,004 ...
Patanè Salvatore - - 2011
Isometric handgrip exercise (HG) was proposed as one of alternative substitute test for the more conventional exercise stress testing but the value of this test alone is limited by a relatively low sensitivity for detecting the presence of coronary artery disease (CAD).On the contrary, the combination of dipyridamole-HG stress with ...
Choi Ran - - 2009
A 7-month-old, female jindo dog was presented with severe ascites, cyanosis, and exercise intolerance. Diagnostic imaging studies revealed Ebstein's anomaly with an atrial septal defect. The dog was managed medically with inotropics, diuretics, and vasodilators.
Thomas Gregory S - - 2009
BACKGROUND: Although vasodilator stress myocardial perfusion imaging (MPI) is increasingly performed with exercise, adenosine A(2A) receptor agonists have not been studied with exercise. OBJECTIVES: To determine the safety of administering regadenoson during exercise and, secondarily, to evaluate image quality, patient acceptance, and detection of perfusion defects. METHODS: Patients requiring pharmacologic ...
Dou Ke-Fei - - 2008
We have recently demonstrated the potential of (18)F-FDG as an imaging marker of myocardial ischemia if injected at peak exercise. However, how long increased (18)F-FDG uptake can be observed after an episode of exercise-induced myocardial ischemia is not known. We performed the current study to determine whether increased regional myocardial ...
Heinzel Alexander - - 2008
OBJECTIVE: We aimed to probe for regional cerebral effects of S-ketamine on in vivo GABA-A-receptor binding in healthy human subjects. METHODS: We investigated I-123-iomazenil SPECT before, during and after administration of S-ketamine in a blinded placebo-controlled study design (n = 12 in both groups). Analyses of SPECT were performed with ...
Rabinovici Gil D GD Memory and Aging Center, University of California San Francisco, San Francisco, CA 94143, USA. - - 2008
Alzheimer's disease (AD) is found at autopsy in up to one third of patients with primary progressive aphasia (PPA), but clinical features that predict AD pathology in PPA are not well defined. We studied the relationships between language presentation, Abeta amyloidosis, and glucose metabolism in three PPA variants using [11C]-Pittsburgh ...
Edison P P Imperial College London, MRC Cyclotron Building, Hammersmith Hospital, Du Cane Road, London W120NN, UK. - - 2008
Neuropathological studies have reported varying amounts of amyloid pathology in dementia with Lewy bodies (DLB) and Parkinson's disease dementia (PDD). [11C]PIB positron emission tomography (PET) is a marker of brain amyloid deposition. The aim of this study was to quantify in vivo amyloid load in DLB and PDD compared with ...
Cittanti Corrado - - 2008
Our purpose was to evaluate the safety profile and biodistribution behavior in healthy human volunteers of the new myocardial perfusion tracer bis[(dimethoxypropylphosphanyl)ethyl]ethoxyethylamine N,N'-bis(ethoxyethyl)dithiocarbamato nitrido technetium(V) (99mTc-N-DBODC). METHODS: Ten healthy male volunteers were injected with 99mTc-N-DBODC under both stress and rest conditions. Anterior and posterior planar gamma-camera images were collected at ...
Bhat Amogh - - 2008
Although exercise electrocardiography (ExECG) is commonly used to detect coronary artery disease, the diagnostic accuracy and reliability of positive (ischemic) results of ExECG in low- and intermediate-risk populations are limited. Accordingly, many patients with positive results of ExECG undergo secondary evaluation using noninvasive stress imaging such as exercise echocardiography. Functional ...
Bishop Gary A - - 2008
A multiyear, on-road emission measurement program carried out in the cities of Chicago, Illinois; Denver, Colorado; Los Angeles (LA), California; and Phoenix, Arizona shows large, fuel-specific tailpipe emissions reductions at all of the sites for carbon monoxide (CO), hydrocarbons (HC), and nitric oxide (NO). CO emissions decreased between 56% (Denver) ...
Sarullo Filippo Maria - - 2008
BACKGROUND: Exercise causes enhanced sympathetic discharge and results in physiologic tachycardia. However, in some patients with a diseased conduction system resulting from acute ischemia, exercise can precipitate heart block. METHODS AND RESULTS: In this report we describe a 51 years old male patient with transient advanced degree atrioventricular (AV) block ...
Haluska Brian A - - 2008
To date, the main cardiovascular application of TDI (tissue Doppler imaging) has been in myocardial evaluation. In the present study, we investigated the feasibility and reproducibility of assessing arterial elasticity using the DC (distensibility coefficient) measured by TDI, the correlation of this with the DC obtained by other methods and ...
Thambyrajah J - - 2008
AIMS: To determine the feasibility of strain rate imaging (SRI) in the objective detection of exercise-induced ischaemia. METHODS AND RESULTS: Sixteen patients undergoing elective percutaneous coronary intervention (PCI) underwent treadmill exercise stress echocardiography (ESE) pre- and post-PCI. Measurement of systolic SRI parameters was attempted in all myocardial segments at baseline, ...
Brinkman Niels - - 2008
BACKGROUND: The aim of this study was to assess whether adenosine impairs left ventricular ejection fraction (LVEF) obtained with gated SPECT in patients with a normal myocardial perfusion scintigram. MATERIALS AND METHODS: This prospective study included 160 consecutive patients with a normal myocardial perfusion scintigraphy (MPS), who were stressed with ...
Ahlberg Alan W - - 2008
BACKGROUND: Combining vasodilator and exercise stress reduces noncardiac side effects, improves image quality, and enhances the detection of ischemia, compared with suboptimal exercise or vasodilator stress alone. However, prognostic data with combined protocols are limited. METHODS AND RESULTS: Consecutive patients (n = 2064) who underwent symptom-limited exercise and dipyridamole stress ...
Tsujikawa Tetsuya - - 2008
OBJECTIVE: There is much controversy about the correlation between the degree of 2-[(18)F]fluoro-2-deoxy-D: -glucose (FDG) uptake and clinical aggressiveness of non-Hodgkin's lymphoma (NHL). In this study, we investigated whether partial volume corrected FDG uptake based on count recovery coefficient in 3D-positron emission tomography (PET)/computed tomography (CT) correlates with the clinical ...
Bedetti Gigliola - - 2008
Diagnosis costs for cardiovascular disease waste a large amount of healthcare resources. The aim of the study is to evaluate the clinical and economic outcomes of alternative diagnostic strategies in low risk chest pain patients. We evaluated direct and indirect downstream costs of 6 strategies: coronary angiography (CA) after positive ...
Jekic Mihaela - - 2008
Treadmill exercise stress testing is an essential tool in the prevention, detection, and treatment of a broad spectrum of cardiovascular disease. After maximal exercise, cardiac images at peak stress are typically acquired using nuclear scintigraphy or echocardiography, both of which have inherent limitations. Although CMR offers superior image quality, the ...
Iliodromitis Efstathios K - - 2008
BACKGROUND: In experimental studies, two windows of preconditioning have been identified, one lasting 1-2h and a second one (SWOP) starting 24h later and lasting 3-4 days. We sought to document SWOP in humans, using scintigraphy as an objective method of imaging. METHODS: Nineteen male patients, aged 62+/-7 years with documented ...
Prasad Asuri N - - 2007
Dysgenesis of the corpus callosum has been recognized as a marker for aberrant development of the central nervous system. It has been suggested that developmental defects of the corpus callosum may be more frequently encountered in patients with inborn errors of metabolism. The objectives of the present study were to ...
Verna Edoardo - - 2007
BACKGROUND: Previous studies have reported larger myocardial perfusion defects with exercise as compared with dipyridamole. The aim of this study was to assess the hypothesis that this mismatch may reflect differences in epicardial and microvascular coronary vasomotor function. METHODS AND RESULTS: The response to intracoronary acetylcholine, nitroglycerin, and adenosine was ...
Yoon Jung Han - - 2007
BACKGROUND: Paroxysmal exercise-induced dystonia is a rare hyperkinetic disease characterized by episodic dystonic attacks after prolonged exercise. However, its pathophysiological and anatomical basis are poorly understood. OBJECTIVE: To explore the exact anatomical location responsible for paroxysmal exercise-induced dystonia by conducting ictal-interictal single-photon emission computed tomography subtraction, which was coregistered to ...
Prajapat Laxman - - 2008
P-wave widening on the 12-lead electrocardiogram denotes abnormal atrial depolarization and has been shown to be associated with myocardial ischemia during treadmill exercise tolerance testing. However, its true significance during dipyridamole (Persantine) stress imaging remains questionable given the potential direct as well as indirect effects of dipyridamole on the atria. ...
Chen Yen-Kung - - 2007
A 31-year-old man underwent a whole-body F-18 fluorodeoxyglucose (FDG) positron emission tomography (PET) scan for cancer screening. There was no history of diabetes, thyroid disease, or noticeable exercise before imaging. The results demonstrated diffusely increased uptake of F-18 FDG in the thyroid and thymus. In addition, there was symmetrically increased ...
David Renaud - - 2008
OBJECTIVES: The aim of the present study was to stress the relationship between neuropsychiatric symptoms and most particularly apathy and striatal dopamine uptake in patients with Alzheimer's disease (AD) or dementia with Lewy body (DLB). PATIENTS AND METHODS: Twenty-two patients (AD n=14; DLB n=8) were included. All patients had neuropsychological ...
Litwiller Daniel V - - 2007
OBJECTIVE: The purpose of this study was to design and evaluate an MRI screening protocol for chronic exertional compartment syndrome (CECS) of the lower legs using an in-scanner exercise protocol and novel dual birdcage coil design for improved imaging. MATERIALS AND METHODS: Coil and phantom studies: a custom-made dual birdcage ...
Poerner Tudor C - - 2007
OBJECTIVE: The aim of this study was to investigate regional myocardial function after atrial switch operation for transposition of the great arteries (TGA) using tissue Doppler echocardiography with strain rate (SR) imaging. METHODS: In all, 24 patients with TGA aged 12 to 33 years and 10 control subjects underwent tissue ...
Candell-Riera Jaume - - 2007
There are no studies in which diagnostic yield of early rest myocardial perfusion gated single-photon emission computed tomography (SPECT), electrocardiographic exercise testing, and stress SPECT were compared in patients with atypical chest pain, nondiagnostic electrocardiograms (ECGs), and negative markers of myocardial damage in the emergency department. A prospective study of ...
Hambÿe Anne-Sophie E - - 2007
AIM: Digestive activity can interfere with the interpretation of myocardial perfusion single photon emission computed tomography using sestamibi or tetrofosmin. Compared with sestamibi, the liver clearance of tetrofosmin is more rapid, but its absolute cardiac uptake is lower. In this study, the activity of sestamibi and tetrofosmin was quantified after ...
Morandi Federica - - 2007
Transsplenic portal scintigraphy using sodium pertechnetate is superior to per-rectal portal scintigraphy due to improved visualization of the portal vasculature with decreased patient and personnel exposure. The purpose of this study was to describe the use of 99mTc-mebrofenin, the radiopharmaceutical of choice for the evaluation of hepatic function, in place ...
Nadig Murali R - - 2007
AIM: We compared the efficacy, side effects of combined handgrip exercise and dobutamine stress with dobutamine stress alone during myocardial perfusion imaging in patients unable to exercise, and in whom vasodilator stress was contraindicated. METHODS: We studied 126 consecutive patients (89 male, 37 female; mean age 63+/-8 years) referred for ...
Davies G R - - 2007
To investigate the presence and evolution of T(1) relaxation time abnormalities in normal-appearing white matter (NAWM) and grey matter (GM), early in the course of relapsing-remitting multiple sclerosis (MS). Twenty-three patients with early relapsing-remitting MS and 14 healthy controls were imaged six monthly for up to three years. Mean follow-up ...
Neglia Danilo - - 2007
To assess whether chronic treatment with carvedilol can increase myocardial blood flow (MBF) and MBF reserve in idiopathic dilated cardiomyopathy (IDC). In a double-blind, placebo-controlled trial, 16 consecutive patients with IDC were randomised to treatment with either carvedilol up to 25 mg twice a day (n = 8, 7 men, ...
Metz Louise D - - 2007
OBJECTIVES: The purpose of this work was to determine the prognostic value of normal exercise myocardial perfusion imaging (MPI) tests and exercise echocardiography tests, and to determine the prognostic value of these imaging modalities in women and men. BACKGROUND: Exercise MPI and exercise echocardiography provide prognostic information that is useful ...
Leischik Roman - - 2007
BACKGROUND: Appraisal of the risk to which outpatients with chest pain are exposed is a major clinical problem. Up to now, there have been no reports on the prognostic significance of exercise stress echocardiography in this patient cohort. PATIENTS AND METHODS: In order to investigate the prognostic significance of exercise ...
Nakajima Kenichi - - 2006
BACKGROUND: Cardiac involvement is an important factor for the appropriate management of systemic sclerosis (SSc). The possibility for detecting early myocardial damage was investigated using (99m)Tc methoxyisobutylisonitrile (MIBI) gated perfusion single photon emission computed tomography (SPECT) and (123)I metaiodobenzylguanidine (MIBG) sympathetic imaging. METHODS AND RESULTS: Twenty-three patients with SSc and ...
Ramakrishna Gautam - - 2006
OBJECTIVES: The purpose of this study was to compare the results and prognostic value of electron-beam computed tomography (EBCT) and exercise echocardiography. BACKGROUND: Although patients with elevated coronary artery calcium scores (CACS) might be referred for exercise echocardiography, the association of EBCT CACS with wall motion score index (WMSI) is ...
Béïque François - - 2006
PURPOSE: To establish Canadian guidelines for training in adult perioperative transesophageal echocardiography (TEE). METHODS: Guidelines were established by the Canadian Perioperative Echocardiography Group with the support of the cardiovascular section of the Canadian Anesthesiologists' Society (CAS) in conjunction with the Canadian Society of Echocardiography. Guidelines for training in echocardiography by ...
Ethell J - - 2006
One hundred and forty one male dental students and staff were screened for colour-defective vision. Ten colour-defective and 20 non colour-defective subjects then carried out a shade matching exercise using nine selected shades and another matched, shade tab (to test for consistency) from Vita shade guides. All shade matching took ...
Lundquist Pinelopi - - 2007
The purpose of this study was to compare two positron emission tomography (PET) tracers that were developed to follow serotonin (5HT) synthesis by performing sequential PET scanning of the same rhesus monkey (n=4) on the same day. alpha-[11C]Methyl-L-tryptophan ([11C]AMT) and 5-Hydroxy-L-[beta-11C]tryptophan ([11C]HTP) are substrates in the first and second enzymatic ...
Oturai P S - - 2006
Chronic exertional compartment syndrome (CECS) of the leg is a common, painful condition related to exercise and associated with increased muscle compartment pressure (CP). Invasive methods are currently the method of choice for diagnosing the condition. We investigated the use of Tc-99m-tetrofosmin perfusion single-photon emission computed tomography (SPECT) as a ...
Goebel Björn - - 2007
PURPOSE OF THE STUDY: The study was done to determine the clinical feasibility and reproducibility of tissue Doppler echocardiography (TDE) with strain rate imaging (SRI) at rest and under physical exercise in healthy young individuals and to report normal values for parameters of regional myocardial function under exercise. METHODS: Forty-five ...
Hummler Helmut D - - 2006
OBJECTIVE: To evaluate the effects of deteriorating perfusion caused by sepsis on the accuracy of pulse oximetry measurements using two more recently available techniques (Nellcor N-395 and Masimo Radical) and to evaluate the perfusion index as a marker of impaired peripheral perfusion to indicate that accuracy of pulse oximetry readings ...
Peteiro Jesús - - 2006
BACKGROUND: Although exercise echocardiography (EE) is not clearly indicated in patients with normal electrocardiogram (ECG) as the first evaluation, there is a lack of data regarding its superiority over the Duke score for prognosis. We investigate whether EE has incremental value over the Duke score for predicting outcome in patients ...
Gehlen Heidrun - - 2006
The purpose of this study was to determine whether the combination of dobutamine and atropine causes cardiac stress equivalent to treadmill exercise. Therefore, electrocardiography and echocardiography were performed on 10 warmblood horses before, during, and after different cardiac stress tests. Stressors consisted of a standardized treadmill exercise and combined administration ...
Masaki Nobuyuki - - 2006
BACKGROUND: The electrocardiographic indices of QT dispersion (QTd), QT peak dispersion (QTpd), and the principal component analysis ratio (PCAr) are related to the occurrence of fatal arrhythmia and are influenced by physical exercise. OBJECTIVE: The purpose of this study was to investigate whether or not the QT parameters can be ...
Anjos Dalton A - - 2006
The assessment of the functional status of the salivary glands has been used in the scintigraphic evaluation of xerostomia. Several quantitative methods derived from standard dynamic scintigraphy have been suggested. However, the indices proposed are quite variable and unlikely to be useful in clinical practice. The objectives of this study ...
Beeres Saskia L M A - - 2006
Bone marrow cell transplantation has been proposed as a novel therapeutic option for patients with coronary artery disease. This study investigated whether autologous bone marrow-derived mononuclear cell injection into the ischemic myocardium of patients with severe angina pectoris could safely reduce anginal symptoms, improve myocardial perfusion, and increase left ventricular ...
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