Search Results
Results 451 - 500 of 782
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Zaman M - - 1994
Exercise Thallium-201 myocardial perfusion imaging is a sensitive technique for detection of CAD. However, in patients unable to perform exercise pharmacological stress with intravenous dipyridamole can be used to dilate coronaries. Out of 125 patients (21 men and 104 women; mean age 52.03 years) evaluated, 110 were considered to be ...
Shammas R L - - 1994
Dipyridamole stress testing may be used in the diagnosis of coronary artery disease and risk assessment of patients who are unable to exercise. Although dipyridamole perfusion imaging has a good safety record, serious side-effects may rarely occur. We present a case in which dipyridamole induced high-grade atrioventricular (AV) block that ...
Alshami A A - - 1994
The purpose of this study was to determine the influence of left ventricular hypertrophy, based on electrocardiographic evidence, on the results of exercise thallium testing. Patients with electrocardiographic evidence of left ventricular hypertrophy (ECG-LVH) and suspected of having coronary artery disease underwent exercise thallium testing. Retrospective analysis of 107 consecutive ...
Blomstrand P - - 1994
To compare modern, digital exercise echocardiography and thallium 201 single-photon emission computed tomography (SPECT) in patients with unstable coronary artery disease, 65 men unselected with regard to echocardiography were prospectively investigated 1 month after an episode of unstable angina or non-Q-wave myocardial infarction. Exercise echocardiography and 201Tl SPECT were performed ...
Billotey C - - 1994
A rapid (25 min) single tracer scintigraphic method to localize parathyroid gland abnormalities was evaluated in 24 patients with hyperparathyroidism. METHODS: Scintigraphy was performed with 99mTc-sestamibi prior to surgery. A 25-min dynamic series centered on the neck was acquired immediately after injection of 99mTc-MIBI. Two planar static views were obtained ...
Raiker K - - 1994
BACKGROUND: The favorable prognostic significance of normal 201Tl stress perfusion images, even in the presence of known coronary artery disease, has been well documented. Relatively few data are available with regard to the prognostic significance of normal planar and single-photon emission computed tomographic (SPECT) stress 99mTc-labeled sestamibi (99mTc-sestamibi) images. METHODS ...
Zanco P L - - 1994
The effects produced on nuclear perfusion images by exercise-induced changes in the heart and respiration rate and possible transient myocardial stunning are not well understood. In this study we attempted to indirectly evaluate the potential artifacts created by exercise-induced changes in cardiac physiology. Twenty patients with prior myocardial infarction and ...
Beleslin B D - - 1994
BACKGROUND: Exercise and pharmacological stress echocardiography have emerged as convenient alternatives to myocardial scintigraphy. The objective of this study was to compare in the same patients the diagnostic values of exercise, dobutamine, and dipyridamole stress echocardiography tests for detection of myocardial ischemia. METHODS AND RESULTS: We performed exercise (maximal treadmill ...
Bisi G - - 1994
Previous studies demonstrate perfusion defect reversibility in 201Tl reinjection imaging performed after the administration of nitrates. This study tests whether the acute sublingual administration of isosorbide dinitrate (ISDN) could improve the capability of 99mTc-teboroxime to detect reversibility in exercise-induced perfusion defects. METHODS: Ten patients with previous myocardial infarction underwent exercise, ...
Szelies B - - 1994
Quantitative topographical EEG was compared with regional glucose metabolism measured by PET with respect to the sensitivity in the classification of mild to moderate dementia. In 24 patients with probable Alzheimer's disease (DAT), 19 patients with vascular dementia (VD) and 15 age-matched healthy controls, global and regional EEG and PET ...
Ambrosi P - - 1994
In patients with hypertrophic cardiomyopathy or systemic hypertension, exercise thallium perfusion defects have been observed but without significant angiographic stenoses. Hypertension and myocardial hypertrophy are common in transplanted heart recipients, and the aim of this study was to determine if exercise thallium scintigraphy false-positives are frequent in transplanted heart recipients. ...
Alazraki N P - - 1994
A detailed analysis of intrapatient reproducibility of exercise SPECT thallium studies is presented. METHODS: Twenty patients in stable condition were re-examined with exercise-redistribution SPECT201 Tl within 3-9 days without intervening procedures. At peak stress, 3.5 mCi 201Tl were given intravenously 1 min prior to exercise termination. SPECT imaging started at ...
Pennell D J - - 1994
Pharmacological stress is vital to the modern nuclear cardiological laboratory. In clinical practice only adenosine, dipyridamole and dobutamine are used. Both adenosine (directly) and dipyridamole (indirectly) work via activation of alpha 2 receptors, which causes vasodilatation. Adenosine has a very short half-life and any adverse effects can be rapidly controlled. ...
Mahmood S - - 1994
201Tl myocardial perfusion single photon emission tomography (SPET) with pharmacological coronary vasodilatation using adenosine is now often used in the investigation of a patient with ischaemic heart disease (IHD). In this study, we present data from two groups of patients. Group A (n = 40) experienced 201Tl SPET with adenosine ...
Mulder B J - - 1994
From 1987 until 1991 a large prospective randomized multicentre study was performed in The Netherlands, Germany and Switzerland entitled CABADAS (Prevention of Coronary Artery Bypass graft occlusion by Aspirin, Dipyridamole, and Acenocoumarol/Phenprocoumon Study). The aim of CABADAS was to evaluate the relative efficacy of (1) aspirin, (2) aspirin plus dipyridamole, ...
Rourk R M - - 1994
OBJECTIVES: It has recently been demonstrated that human esophageal mucosa, containing numerous submucosal mucous glands, has the ability to elaborate significant amounts of esophageal epidermal growth factor (eEGF). Because of its role in the maintenance of the integrity of the esophageal mucosa, we elected to study the rate of secretion ...
Cuocolo A - - 1994
We compared the results of adenosine and bicycle exercise 99mTc-methoxy isobutyl isonitrile (MIBI) myocardial SPECT in 22 patients (18 males and 4 females, mean age 51 +/- 11 yr) with angiographically documented coronary artery disease (CAD). METHODS: All patients were submitted on separate days to three intravenous injections of 99mTc-MIBI ...
Simons M - - 1994
BACKGROUND: The availability of clinical information often influences the interpretation of diagnostic imaging information. METHODS AND RESULTS: In this study we examined the impact of such data on interpretation of exercise thallium scans and the differences in analysis of such information between radiologists and clinicians. Two hundred thirty-seven exercise tolerance ...
Marangelli V - - 1994
OBJECTIVES: This study assessed and compared the diagnostic potential of exercise, transesophageal atrial pacing and dipyridamole stress echocardiography in a clinical setting. BACKGROUND: Although they have been widely studied, no data exist with regard to comparisons of these procedures in a head-to-head study in different clinical settings. METHODS: One hundred ...
Arora G D - - 1994
To determine the influence of tobacco abuse on thallium 201 lung uptake during exercise, we examined 185 consecutive subjects with normal myocardial perfusion scans and without electrocardiographic evidence of left ventricular hypertrophy. The subjects were divided into two groups: group 1 subjects (n = 60) had histories of smoking and ...
Nap A M - - 1994
Thyroidal 99mTcO4- (pertechnetate) uptake percentages were determined in unanesthetized euthyroid (n = 13) and hyperthyroid (n = 18) cats. Maximal uptakes were observed 60 minutes after IV injection of the radionuclide and ranged from 0.3 to 3.9% of the dose in euthyroid cats (median 2.23%) and from 5.2% to 23.9% ...
Marwick T H - - 1994
OBJECTIVE: To compare the ability of dobutamine and exercise stress to induce myocardial ischaemia and perfusion heterogeneity under routine clinical circumstances. DESIGN: 86 active patients without previous myocardial infarction were studied by dobutamine and exercise stress protocols and coronary angiography. During both tests patients underwent electrocardiography, digitised echocardiography, and perfusion ...
Denvir M A - - 1994
A detailed comparison of stress thallium images utilizing exercise (symptom-limited bicycle ergonometer) and adenosine (infused at 50 micrograms kg-1 min-1 increasing by 25 micrograms kg-1 min-1 every 2 min to a maximum tolerated dose) was performed in 20 patients with angiographically documented coronary disease. Ten patients were receiving beta-blockade at ...
Minoda K - - 1994
Exercise and hyperventilation tests are often used as the provocative tests for coronary artery spasm. To examine the distribution of myocardial blood flow during exercise-induced and hyperventilation-induced attacks of coronary spasm, thallium-201 myocardial scintigraphy was performed in 47 patients with variant angina. The extent and severity scores and severity index ...
Grover-McKay M - - 1994
In patients who cannot perform treadmill exercise, both intravenous dipyridamole and arm exercise have been used with thallium-201 scintigraphy to detect significant coronary artery disease. However, no study has directly evaluated the results of intravenous dipyridamole and arm exercise thallium scintigraphy as compared with coronary angiography. It was the purpose ...
Sakata K - - 1994
This study was performed to assess the value of washout rate analysis of quantitative exercise thallium-201 emission computed tomography in vasospastic angina patients without significant coronary stenosis. Quantitative analysis of both thallium-201 perfusion and washout rate before and after drug treatment was performed in 48 patients with vasospastic angina and ...
Walamies M - - 1994
Myocardial metabolism in exercise was determined by studying 21 syndrome X patients and 14 healthy volunteers with an aromatic fatty acid analogue IPPA and a gamma camera. We developed criteria for visual semiquantitative assessment of relative segmental radiotracer uptake and washout, and tested a new computer program for quantitative evaluation. ...
Hoffmann R - - 1994
Non-invasive documentation of restenosis after successful percutaneous transluminal coronary angioplasty (PTCA) remains a problem. Thus, transoesophageal pacing echocardiography (TPE) with simultaneous rapid atrial pacing via the same probe, a recently validated method for detection of coronary artery disease, was used in 60 patients for detection of restenosis after successful PTCA ...
Grip L - - 1994
Eighteen patients with stable exertional angina pectoris were investigated by thallium-201 (201Tl) exercise and redistribution single photon emission computed tomography (SPECT) after coronary angiography. Eight of the patients had a previous myocardial infarct. Six patients had single-, eight double- and four triple-vessel disease. An exercise SPECT was acquired 10 min ...
Takeishi Y - - 1994
Thallium-201 (Tl-201) distribution during adenosine infusion was assessed quantitatively and compared with that of exercise imaging. Adenosine and exercise Tl-201 single-photon emission computed tomography (SPECT) were performed in 40 patients with suspected coronary artery disease. In the whole-body images (n = 5) and the unprocessed anterior projection images acquired as ...
Wackers F J - - 1994
The role of physical exercise in myocardial perfusion imaging is critical for two reasons: (1) stress is essential to create heterogeneity of blood flow in myocardial regions supplied by normal versus stenosed coronary arteries and (2) exercise data provide invaluable information that can influence the interpretation of perfusion images. Image ...
Leppo J A - - 1994
Dipyridamole is a pharmacologic stressor used in place of exercise for myocardial perfusion imaging in patients who cannot exercise due to various physical limitations. Perfusion studies with dipyridamole can identify coronary artery disease (CAD) as accurately as maximal exercise stress testing. In addition, dipyridamole myocardial perfusion studies are useful to ...
Dovgan D J - - 1994
The purpose of this study is to determine the range of maximal diaphragmatic crural thickness during different phases of respiration and to correlate crural thickness with age and gender. Prospective evaluation of computed tomographic (CT) scans of 200 patients without juxtacrural abnormalities was performed. Maximal short-axis crural thickness measurements were ...
Lette J - - 1994
Exercise myocardial perfusion imaging with Tc-99m sestaMIBI is routinely used to detect underlying coronary stenoses. Ischemia is diagnosed in regions that display decreased tracer uptake during exercise as compared to rest. Tc-99m sestaMIBI SPECT images of 42 healthy volunteers were assessed both qualitatively (tomographic slices) and quantitatively (sectored polar map) ...
Verani M S - - 1994
Dobutamine, a pharmacologic stressor, is useful for myocardial perfusion imaging in patients who cannot exercise. Patients with asthma or severe chronic obstructive pulmonary disease who are at risk for adverse effects from either dipyridamole or adenosine are prime candidates for dobutamine perfusion studies. Dobutamine is a predominant beta-1 agonist that ...
Lee J - - 1994
There are currently four common types of stress used with thallium-201 imaging in the diagnosis of coronary artery disease and risk assessment. The objective of this study was to examine the thallium biokinetics during exercise, adenosine, dipyridamole and dobutamine stress testing in 15 healthy volunteers. METHODS: Each subject underwent planar ...
Gimple L W - - 1994
The use of physiologic testing for prognostication continues to be useful and widely applied in the predischarge evaluation of patients recovering from an uncomplicated acute myocardial infarction in the thrombolytic era. Because patients with abnormal exercise test results are now routinely sent for angiography, there are no randomized trials or ...
Pennell D J - - 1994
There are a number of stress techniques in common use for 201Tl myocardial imaging but few studies have been performed comparing the biodistribution of 201Tl in each case. METHODS: We studied 36 normal patients after six different stress regimens by whole-body imaging, 40 min after 201Tl injection. The stress regimens ...
Iskandrian A S - - 1994
BACKGROUND: This study compared the prognostic value of exercise single-photon emission computed tomographic (SPECT) thallium imaging with that of treadmill exercise score in medically treated patients with coronary artery disease (CAD). METHODS AND RESULTS: The treadmill exercise score was derived from exercise duration, degree of ST segment depression, and the ...
al-Tikriti M S - - 1994
The regional brain distribution and pharmacological specificity of three high affinity tracers for the dopamine (DA) D2 receptor: [123I]IBF, [123I]epidepride, and [123I]2'-ISP were assessed by SPECT imaging of non-human primates. The ratios of striatal-to-occipital activities at the time of peak striatal uptake were 2.2, 6.3 and 1.7, respectively. From the ...
Weindling S N - - 1994
OBJECTIVES: This study was conducted to determine the prevalence of myocardial perfusion abnormalities at rest and exercise and to assess exercise capacity in children after the arterial switch operation. BACKGROUND: There have been sporadic reports of myocardial ischemia or sudden death in children after the arterial switch operation for transposition ...
Tawarahara K - - 1994
To assess the clinical value of simultaneous dual myocardial imaging with iodine-123-beta-methyl-iodophenyl-pentadecanoic acid (123I-BMIPP) and thallium-201 (201Tl), myocardial imaging was performed at rest and during exercise in seven patients with coronary heart disease. When 123I-BMIPP and 201Tl images were compared, the initial exercise and resting images agreed 87% and 64%, ...
Herman S D - - 1994
Studies using dobutamine thallium-201 myocardial perfusion imaging have suggested a high sensitivity and specificity for the detection of coronary artery disease. However, few data are available comparing dobutamine with exercise stress for the detection and localization of perfusion defects. This study compared the effects of dobutamine and exercise stress using ...
Miletich R S - - 1994
Regional cerebral perfusion was assessed in six patients with asymmetric Parkinson's disease (PD) of mild to moderate severity and in six matched normal subjects using 99mTc-bicisate single photon emission computed tomography (SPECT). Regional activity was normalized to whole-brain activity. Each subject was studied twice, separated by 15.2 +/- 9.2 and ...
Barasch E - - 1994
Stress echocardiography has been developed in recent years as an effective noninvasive test for the detection and assessment of coronary artery disease. This method combines exercise with 2-dimensional echocardiography, which can assess regional and global left ventricular function during stress. Dobutamine infusion, a pharmacologic means of producing cardiovascular stress, appears ...
Santos-Ocampo C D - - 1994
BACKGROUND: Pharmacologic stress has been shown in animal studies to induce high degrees of myocardial hyperemia. At these levels of myocardial blood flow, the myocardial uptake of technetium 99m sestamibi may plateau and may affect the diagnostic accuracy. This study compared the effects of myocardial hyperemia induced by exercise, dipyridamole, ...
Yamagami H - - 1994
To test the clinical significance of technetium-99m teboroxime regional myocardial clearance in the detection of coronary artery disease, 25 patients underwent dynamic planar or single-photon emission tomographic (SPET) myocardial imaging with 99mTc-teboroxime after exercise and again 2 h later at rest. All patients underwent both thallium-201 exercise and redistribution SPET ...
Casanova R - - 1994
Restenosis remains the main limitation of percutaneous transluminal coronary angioplasty (PTCA). Since it seems likely that restenosis not severe enough to induce ischemia may be better detected with pharmacological testing than with exercise, we investigated whether dipyridamole thallium scintigraphy is better than exercise-electrocardiogram and exercise-thallium in predicting restenosis after PTCA. ...
Yoshioka H - - 1994
We evaluated the acute changes in exercised muscle using magnetization transfer contrast (MTC) MR imaging with a short repetition time sequence. Ten volunteers performed supine ankle dorsiflexion exercise. MTC gradient-recalled echo (GRE) images were obtained before and after exercise at 1.5 T. The effect of MTC was assessed by dividing ...
Ignaszewski A P - - 1993
Dipyridamole-induced coronary hyperemia with 201Tl myocardial perfusion scintigraphy can detect ischemic regions in individuals unable to perform adequate exercise, but it has several limitations. Symptom-limited exercise supplementation to intravenous dipyridamole can potentially overcome them, but the safety and diagnostic accuracy for this combination has not been established. Between 1987 and ...
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