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- - 2013
The 2013 Canadian Cardiovascular Society Heart Failure Management Guidelines Update provides focused discussions on the management recommendations on 2 topics: (1) exercise and rehabilitation; and (2) surgical coronary revascularization in patients with heart failure. First, all patients with stable New York Heart Association class I-III symptoms should be considered for ...
Ulimoen Sara R - - 2013
Rate control of atrial fibrillation (AF) has become a main treatment modality, but we need more knowledge regarding the different drugs used for this purpose. In this study, we aimed to compare the effect of four common rate-reducing drugs on exercise capacity and levels of N-terminal pro-B-type natriuretic peptide (NT-proBNP) ...
Buber Jonathan - - 2014
As the longevity of patients with congenital heart disease improves, the number surviving to adulthood will continue to rise. Consequently, practicing physicians can expect to encounter an increasing number of adult patients with various congenital cardiac conditions. Impaired exercise tolerance in this patient population is exceptionally common; adult patients with ...
Edelmann Frank - - 2013
To investigate the interaction of clinical characteristics with disease characterising parameters in heart failure with preserved ejection fraction (HFpEF). Methods and results In the multicenter, randomized, placebo-controlled, double-blinded, Aldo-DHF trial investigating the effects of spironolactone on exercise capacity (peakVO2) and diastolic function (E/e') n=422 patients with HFpEF (age 67±8years, 52% ...
Westhoff-Bleck Mechthild - - 2013
Exercise training safely and efficiently improves symptoms in patients with heart failure due to left ventricular dysfunction. However, studies in congenital heart disease with systemic right ventricle are scarce and results are controversial. In a randomised controlled study we investigated the effect of aerobic exercise training on exercise capacity and ...
Karner-Rezek Klaus - - 2013
Atrial natriuretic peptides (ANP) and Brain natriuretic peptides (BNP) stimulate fat cell plasma membrane receptors. They are potent lipolytic agents on isolated fat cells from subcutaneous adipose tissue. The physiological effects of continuous endurance exercise on ANP release and plasma free fatty acids (FFA) concentrations have been well described. The ...
Stewart Glenn M - - 2013
Although markers of myocyte injury, electrolyte disturbances and an autonomic imbalance have been reported following exercise, the effect of prolonged strenuous activity on cardiac electrical conduction is not well understood. This study examined atrial and ventricular conduction dynamics during recovery from exercise. Electrocardiographic intervals were obtained from eight highly-trained males ...
Badran Hala Mahfouz - - 2013
Although patients with hypertrophic cardiomyopathy (HCM) have normal ejection fractions at rest, the investigators hypothesized that these patients have differentially abnormal systolic function reserves, limiting their exercise capacity compared with patients with hypertension (HTN). Forty patients with HCM (mean age, 39.1 ± 12 years), 20 patients with HTN with LVH, and 33 ...
Wang Jing - - 2013
We evaluated the left ventricular (LV) performance in patients with heart failure and preserved ejection fraction (HFPEF) during exercise as compared to those with heart failure and reduced ejection fraction (HFREF) and healthy subjects. All subjects received echocardiographic (Vivid7, GE Healthcare) examination with symptom-limited exercise testing on a semi-recumbent and ...
Salvagno Gian Luca - - 2013
Abstract Background: The leading mechanisms responsible for the most prevalent and serious cardiac injuries include myocardiocyte stretch, myocardiocyte necrosis and cardiac fibrosis, which can now be reliably mirrored by measurement of natriuretic peptides, cardiospecific troponins and galectin-3, respectively. Although a large amount of knowledge has been gathered about the behavior ...
Molenaar M M D - - 2013
Although cardiac resynchronisation therapy (CRT) is an established treatment to improve cardiac function, a significant amount of patients do not experience noticeable improvement in their cardiac function. Optimal timing of the delay between atrial and ventricular pacing pulses (AV delay) is of major importance for effective CRT treatment and this ...
Compostella Leonida - - 2013
Axial-flow left ventricular assist devices (LVADs) are increasingly used as destination therapy in end-stage chronic heart failure (CHF), as they improve survival and quality of life. Their effect on exercise tolerance in the early phase after implantation is still unclear. The aim of this study was to evaluate the effect ...
Pardaens Sofie - - 2013
Exercise intolerance is a hallmark feature of chronic heart failure and is associated with poor prognosis. This review provides an update on cardiopulmonary exercise variables, proven to be prognostically important in heart failure. Besides the widely accepted peak oxygen consumption (peak VO2) and VEN/VCO2 slope, other exercise variables - exercise ...
Chrysohoou Christina - - 2013
The aim of this study was to evaluate the effect of high intensity, interval exercise on quality of life (QoL) and depression status, in chronic heart failure (CHF) patients. A randomized controlled trial (phase III). Of the 100 consecutive CHF patients (NYHA class II-IV, ejection fraction≤50%) that were randomly allocated ...
Gąsiorowski Adam - - 2013
Chronic heart failure (CHF) is a complex disease process connected with cardiovascular system as well as other organs and skeletal muscles. In connection with the above, cardiac rehabilitation, consisting of exercise training and diet supplementation, aims at recovery of physical, social and psychic function and removing risk factors influencing the ...
Holdsworth Clark T CT a Department of Anatomy and Physiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506-5802, - - 2014
Impaired vasomotor control in chronic heart failure (CHF) is due partly to decrements in nitric oxide synthase (NOS) mediated vasodilation. Exercising muscle blood flow (BF) is augmented with polyunsaturated fatty acid (PUFA) supplementation via fish oil (FO) in healthy rats. We hypothesized that FO would augment exercising muscle BF in ...
Fournier Sara B - - 2013
MetS is the manifestation of a cluster of cardiovascular (CV) risk factors and is associated with a three-fold increase risk of CV morbidity and mortality, which is suggested to be mediated, in part, by resting left ventricular (LV) systolic dysfunction. However, to what extent resting LV systolic function is impaired ...
Chan Kwan Leung - - 2013
-We have observed that elevated mitral gradients (EMG) can develop in some patients following mitral valve repair for degenerative mitral regurgitation. -We screened 275 patients who had mitral valve repair involving more than one leaflet scallop between October 2001 and July 2010. Mitral valve hemodynamics were assessed at rest and ...
Takagi Tsutomu - - 2013
To determine whether elevated left ventricular (LV) filling pressure estimated by raised Doppler E velocity to tissue Doppler E' velocity ratio (E/E') after exercise is associated with increased risk of new-onset atrial fibrillation (AF) in non-ischemic elderly patients. Prognostic importance of exercise induced LV diastolic dysfunction remains uncertain. We studied ...
Roentgen Philipp - - 2013
Cardiopulmonary exercise capacity is often reduced in patients with transposition of the great arteries after atrial switch operation. Reduced exercise capacity may be caused by deterioration of systemic right ventricular function over time. This study analyzed serial changes in systemic right ventricular function and cardiopulmonary exercise capacity in young adults ...
Fuchs Therese T Arrhythmia Service, Assaf Harofeh Medical Center, Zerifin, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel. - - 2013
Sudden death in athletes can occur during sport activities and is presumably related to ventricular arrhythmias. To investigate the long-term follow-up ofathletes with ventricular arrhythmias during an exercise test. From a database of 56,462 athletes we identified 192 athletes (35 years old who had ventricular arrhythmias during an exercise test. ...
Zizola Cynthia C Division of Cardiology, Department of Medicine, Center for Advanced Cardiac Care, Columbia University Medical Center, 622 West 168th Street, PH 10, Room 203, New York, NY, 10032, - - 2013
Physiologic endurance exercise performance is primarily limited by cardiac function. In patients with heart failure, there is dissociation between cardiac performance and exercise capacity, suggesting a distinct role of abnormal peripheral organ function, including skeletal muscle function. The impact of heart failure upon skeletal muscle and exercise performance will be ...
Bussoni M F - - 2013
Exercise capacity and quality of life (QOL) are important outcome predictors in patients with systolic heart failure (HF), independent of left ventricular (LV) ejection fraction (LVEF). LV diastolic function has been shown to be a better predictor of aerobic exercise capacity in patients with systolic dysfunction and a New York ...
Boissière Julien - - 2013
In adults, left ventricular (LV) systolic twist is an important factor that determines LV filling, both at rest and during exercise. In children, lower LV twist has been demonstrated at rest, but its adaptation during exercise and its functional consequences on LV filling are unknown. Using speckle-tracking echocardiography, LV twist-untwist ...
Blessberger Hermann - - 2013
Left atrial catheter ablation (LACA) is routinely used in the management of recurrent atrial fibrillation. We report a patient suffering from vasospastic angina 2months after a LACA procedure. Typical clinical symptoms, ST-segment changes during exercise test and successful treatment with nicorandil led to the diagnosis. According to our hypothesis, destruction ...
Klempfner Robert - - 2013
Recent data suggest that exercise training (ET) confers significant symptomatic and functional improvements in patients with diastolic dysfunction, and thus may be beneficial in patients with hypertrophic cardiomyopathy (HCM). However, there are no data regarding the safety or efficacy of ET in HCM patients. A prospective non-randomized intervention design was ...
King Gerard - - 2013
"To go too far is as bad as to fall short."Confucius (BC 551-BC 479) Chinese philosopher Echocardiography has contributed most to our current understanding and indeed our current dilemma regarding the heart of the endurance athlete. Echocardiography assesses and characterizes nicely the effects of Endurance exercise training. It allows us ...
Tabet Jean-Yves - - 2013
Exercise capacity, best reflected by peak exercise oxygen consumption (peak VO2), is a powerful prognostic factor in patients with chronic heart failure (CHF). However, the optimal time to assess exercise capacity for prognosis remains unclear and whether an exercise training program (ETP) to improve exercise capacity alters the prognostic value ...
Rajati Fatemeh F Department of Public Health, Faculty of Health, Kermanshah University of Medical Sciences, Kermanshah, - - 2013
Regular exercise has been associated with improved quality of life (QoL) in patients with heart failure (HF). However, less is known on the theoretical framework, depicting how educational intervention on psychological, social, and cognitive variables affects physical activity (PA). The purpose of this study is to assess the effectiveness of ...
Kosmala Wojciech W Wroclaw Medical University, Wroclaw, - - 2013
The aim of this study was to test the effects of treatment with ivabradine on exercise capacity and left ventricular filling in patients with heart failure with preserved ejection fraction (HFpEF). Because symptoms of HFpEF are typically exertional, optimization of diastolic filling time by controlling heart rate may delay the ...
Eindhoven Jannet A JA Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, the - - 2013
The aim of this study was to determine the value of N-terminal pro-B-type natriuretic peptide (NT-proBNP) in adults with congenital heart disease (CHD) and investigate its relationship with ventricular function and exercise capacity. NT-proBNP may detect early deterioration in cardiac function. In this cross-sectional study, extensive echocardiography, exercise testing, and ...
Oliveira Mayron F - - 2013
Exercise capacity and cerebral oxygenation are reduced in COPD-heart failure overlap compared to COPD in isolation.
Grundvold Irene I Department of Cardiology, Oslo University Hospital, Ullevaal, - - 2013
Low resting heart rate (HR) has been associated with atrial fibrillation (AF) in athletes. We aimed to study whether low HR at rest or during exercise testing was a predictor of AF in initially healthy middle-aged men. A total of 2014 healthy Norwegian men participated in a prospective cardiovascular survey, ...
Kaltsatou Antonia Ch - - 2013
Objective:To compare the effects of traditional dancing with formal exercise training in terms of functional and cardiovascular benefits and motivation in patients with chronic heart failure.Design:Randomized controlled trial.Setting:Sports Medicine Laboratory.Subjects:Fifty-one Greek male patients aged 67.1±5.5 years with chronic heart failure of New York Heart Association (NYHA) class II-III, participated in ...
Stockburger Martin - - 2013
Previous studies showed unfavourable effects of right ventricular (RV) pacing. Ventricular pacing (VP), however, is required in many patients with atrioventricular (AV) block. The PREVENT-HF study explored left ventricular (LV) remodelling during RV vs. biventricular (BIV) pacing in AV block without advanced heart failure. The pre-specified PREVENT-HF German Substudy examined ...
Schnell Frédéric - - 2013
Hypertrophic cardiomyopathy (HCM) and aortic stenosis (AS) may influence left ventricular (LV) systolic function, despite preservation of LV ejection fraction. The aim of this study was to determine the relative importance of cardiac afterload and myocardial hypertrophy in the potential dysfunction of myocardial deformation, at rest and during standardized exercise. ...
Chiari Stefania - - 2013
To assess the occurrence of tidal expiratory flow limitation (EFL) and/or dynamic pulmonary hyperinflation (DH) in chronic heart failure (CHF) during exercise 15 patients with stable systolic CHF, aged 69±6 yr, underwent pulmonary function testing and incremental cardio-pulmonary exercise testing. They subsequently performed constant load exercise testing at 30, 60 ...
Cox Emily J - - 2013
Exercise causes physiological cardiac hypertrophy and benefits the diabetic heart. Mammalian switch-independent 3A (mSin3A) and histone deacetylases (HDACs) 1 and 2 regulate hypertrophic genes through associations with the DNA binding proteins repressor element-1 silencing transcription factor (REST) and O-linked beta-N-acetylglucosamine transferase (OGT). O-linked beta-N-acetylglucosamine (O-GlcNAc) is a glucose derivative that ...
Ciurzyński Michał - - 2013
High prevalence of exaggerated pulmonary artery pressure response to exercise (EPAPR) was reported in patients with systemic sclerosis (SSc). However, pathophysiology of this phenomenon has not been well defined. Therefore, we evaluated the frequency and potential aetiology of EPAPR in SSc patients. We included 85 patients (79 female, 6 male, ...
Tanaka M - - 2013
Background: Evaluation of the contractile state of the left ventricle during exercise is important in drawing up a protocol of cardiac rehabilitation. It has been demonstrated that color Doppler- and echo tracking-derived carotid arterial wave intensity is a sensitive index of global left ventricular (LV) contractility.
Ma Zhichao - - 2013
Swimming exercise leads to a nonpathological, physiological left ventricular hypertrophy. However, the potential molecular mechanisms are unknown. We investigated the role of microRNAs (miRNA) regulating the cardiac signal cascades were studied in exercised rats. Female Wistar rats were assigned into two groups: (1) sedentary control (SC), (2) swimming exercise (SE). ...
Piña Ileana L - - 2013
Anemia is common in patients with chronic heart failure (HF), with a prevalence ranging from 10% to 56%, and may be a risk factor for poor outcomes. Anemia in HF remains poorly understood, with significant gaps in its impact on health-related quality of life (HRQoL), with most studies in HF ...
Lafitte Stéphane - - 2013
To analyze left ventricular (LV) obstruction in hypertrophic cardiomyopathy (HCM) during exercise echocardiography. Despite the association of symptoms with LV outflow tract obstruction in HCM, there exist paradoxical situations in which significant intraventricular gradients (>50 mmHg) at rest occur in conjunction with excellent exercise tolerance. To examine this phenomenon we ...
Ferreira Eloara Vm - - 2013
Increased ventilatory ($$\stackrel{\cdot }{\hbox{ V }}$$E) response to carbon dioxide output ($$\stackrel{\cdot }{\hbox{ V }}$$CO2) is a key finding of incremental cardiopulmonary exercise testing in both heart failure and pulmonary arterial hypertension (PAH). As with heart failure, measures of excessive exercise ventilation considering high-to-peak exercise $$\stackrel{\cdot }{\hbox{ V }}$$E-$$\stackrel{\cdot }{\hbox{ ...
Morvan Eduardo - - 2013
BACKGROUND: The increase in fructose consumption is paralleled by a higher incidence of metabolic syndrome, and consequently, cardiovascular disease mortality. We examined the effects of 8 weeks of low intensity exercise training (LET) on metabolic, hemodynamic, ventricular and vascular morphological changes induced by fructose drinking in male rats. METHODS: Male ...
Eleid Mackram F - - 2013
Retroperitoneal fibrosis is a rare condition characterized by the presence of inflammatory and fibrous retroperitoneal tissue that surrounds and often encases abdominal structures. In this report we describe an unusual presentation of retroperitoneal fibrosis and inferior vena cava (IVC) obstruction that was unidentified by noninvasive testing and ultimately diagnosed using ...
Reichenberger Frank - - 2013
Background A variation in right atrial and pulmonary arterial pressure might result in a shunt dynamic across a patent foramen ovale (PFO). In the present study we tested if peak exercise facilitates a restoration of right to left shunt (RLS) in stroke patients who demonstrated a functional PFO closure (no ...
Ito Daisuke - - 2013
There is an interaction between heart and kidney diseases, which is a condition termed cardiorenal syndrome. Exercise training has cardioprotective effects, involving upregulation of endothelial nitric oxide synthase (eNOS) in the cardiovascular system. However, the effects of exercise training on nitric oxide synthase (NOS) in the kidney with heart disease ...
Nunes Ramiro B - - 2013
The aim of the present study was to evaluate the effect of 8 weeks of aerobic exercise training on cardiac functioning and remodeling and on the plasma levels of inflammatory cytokines in chronic heart failure rats. Wistar rats were subjected to myocardial infarction or sham surgery and assigned to 4 ...
Boyle Kyndall L - - 2013
Lumbopelvic-femoral conditions are common and may be associated with asymmetrical musculoskeletal and respiratory impairments and postural mal-alignment called a Left Anterior Interior Chain (AIC) pattern. An inherent pattern of asymmetry involves the trunk/ribs/spine/pelvis/hip joints and includes the tendency to stand on the right leg and shift the center of gravity ...
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