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Stolker Joshua M - - 2006
In patients with heart failure (HF), peak exercise oxygen consumption (VO2) is an important prognostic tool on which critical clinical decisions are made. However, recent retrospective data have suggested that ventilatory equivalent (VE = ventilation [liters per minute]/VO2 [liters per minute]) may be a stronger predictor of outcomes than VO2 ...
Mercuro Giuseppe - - 2006
BACKGROUND: Healthy postmenopausal women reveal a series of peripheral vascular abnormalities, whose possible consequences on exercise performance has not been yet elucidated. METHODS: We studied the response to strenuous exercise in 25 postmenopausal women (mean age 50 +/- 3 years) without cardiovascular risk factors or disease through an integrative cardiopulmonary ...
Bussotti Maurizio - - 2006
BACKGROUND: Exercise-induced ST changes, suggestive of cardiac ischaemia, are found in asymptomatic patients. METHODS: Gas exchange kinetics were studied during exercise to help to separate patients affected by epicardial coronary disease from those without. Forty-eight patients, without angina symptoms and showing significant changes of ST during exercise, underwent a coronarography ...
Dufour Stéphane P - - 2006
This study investigates whether a 6-wk intermittent hypoxia training (IHT), designed to avoid reductions in training loads and intensities, improves the endurance performance capacity of competitive distance runners. Eighteen athletes were randomly assigned to train in normoxia [Nor group; n = 9; maximal oxygen uptake (VO2 max) = 61.5 +/- ...
Berger Nicolas J A - - 2006
PURPOSE: To examine the relative effectiveness of moderate-intensity continuous training and high-intensity interval training on pulmonary O2 uptake (VO2) kinetics at the onset of moderate- and severe-intensity cycle exercise in previously sedentary subjects. METHODS: Twenty-three healthy subjects (11 males; mean +/- SD age 24 +/- 5 yr; VO2peak 34.3 +/- ...
Turner Anthony P - - 2006
PURPOSE: To investigate the kinetics of O2 uptake (VO2) and m. vastus lateralis [deoxyhemoglobin] ([Hb]) (near-infrared spectroscopy) for supramaximal intermittent cycling. METHODS: Six males performed a ramp test for determination of VO2peak and lactate threshold. On different days, they completed four intermittent "work:recovery" tests (10 s:20 s, 30 s:60 s, ...
Kang J - - 2006
AIM: The present investigation was undertaken to elucidate the differences in the progression of metabolic responses during incremental exercise between men and women of similar maximal aerobic capacity. METHODS: Twenty males and 20 females served as subjects for the study. Each subject was randomly assigned to perform a graded exercise ...
Akbulut Tamer - - 2006
The aim of this study was to evaluate the effects of the combination of enalapril and losartan in patients with left ventricular systolic dysfunction by means of cardiopulmonary exercise test (CPET). Patients with left-ventricular systolic dysfunction and ejection fractions of 40% or less were included to the study. All patients ...
Ulubay G - - 2006
It is well known that reduced peak oxygen uptake (peak VO2) is a predictor for mortality in several chronic diseases and during the preoperative period. The aim of this study was to investigate the factors that influence peak VO2 in renal transplant candidates receiving continuous ambulatory peritoneal dialysis (CAPD) therapy. ...
Caputo F - - 2006
The objective of this study was to analyze, in triathletes, the possible influence of the exercise mode (running x cycling) on time to exhaustion (TTE) and oxygen uptake (VO2) response during exercise performed at the intensity associated with the achievement of maximal oxygen uptake (IVO2max). Eleven male triathletes (21.8 +/- ...
Carter H - - 2006
Accurate classification of VO2 kinetics is essential to correctly interpret its control mechanisms. The purpose of this study was to examine VO2 kinetics in severe and supra-maximal intensity running exercise using two modelling techniques. Nine subjects (mean +/- S.D: age, 27 +/- 7 years; mass, 69.8 +/- 9.0 kg; VO2max, ...
Sheel A William - - 2006
Ventilatory responsiveness to hypoxia (HVR) has been reported to be different between highly trained endurance athletes and healthy sedentary controls. However, a linkage between aerobic capacity and HVR has not been a universal finding. The purpose of this study was to examine the relationship between HVR and maximal oxygen consumption ...
Budts Werner - - 2006
BACKGROUND: After Mustard or Senning repair for transposition of the great arteries (d-TGA), qualitative assessment of the systemic right ventricle remains difficult. We wanted to evaluate the relationship between demographic and echocardiographic variables, and exercise performance. METHODS: In 22 consecutive d-TGA patients (9 Mustard and 13 Senning) a standard transthoracic ...
Elder Christopher P - - 2006
BACKGROUND: Oxygen cost of different muscle actions may be influenced by different recruitment and rate coding strategies. The purpose of this study was to account for these strategies by comparing the oxygen cost of dynamic and isometric muscle actions relative to the muscle mass recruited via surface electrical stimulation of ...
Maeder Micha - - 2006
PURPOSE: Guidelines suggest that individualized ramp protocols with treadmill times targeted between 8 and 12 minutes are most suitable to estimate exercise capacity. However, previous methods to determine individualized ramp rates and comparisons between ramp and standardized protocols have been limited to clinically referred populations. METHODS: Forty-three healthy volunteers [median ...
Widman Lana M LM Department of Physical Medicine and Rehabilitation, University of California, Davis Medical Center, 4860 Y Street, Suite 1113, Sacramento, CA 95817, USA. - - 2006
To determine whether a new upper extremity exercise device integrated with a video game (GameCycle) requires sufficient metabolic demand and effort to induce an aerobic training effect and to explore the feasibility of using this system as an exercise modality in an exercise intervention. Pre-post intervention. University-based research facility. SUBJECT ...
Østergård Torben - - 2006
First-degree relatives of type 2 diabetic patients (offspring) are often characterized by insulin resistance and reduced physical fitness (VO2 max). We determined the response of healthy first-degree relatives to a standardized 10-wk exercise program compared with an age-, sex-, and body mass index-matched control group. Improvements in VO2 max (14.1 ...
Ponsot Elodie - - 2006
This study investigates whether adaptations of mitochondrial function accompany the improvement of endurance performance capacity observed in well-trained athletes after an intermittent hypoxic training program. Fifteen endurance-trained athletes performed two weekly training sessions on treadmill at the velocity associated with the second ventilatory threshold (VT2) with inspired O2 fraction = ...
Chryssanthopoulos Stavros N - - 2005
AIM: The aim of the study was to correlate the score derived from Specific Activity Questionnaire (SAQ), Left Ventricular Dysfunction 36 (LVD 36) and the Minnesota Living with Heart Failure Questionnaire (LIhFE) with peak oxygen consumption measured during maximal treadmill exercise spirometry in patients with heart failure. METHODS: We prospectively ...
Trappe Todd - - 2006
To determine the influence of a 17-day exposure to real and simulated spaceflight (SF) on cardiorespiratory function during exercise, four male crewmembers of the STS-78 space shuttle flight and eight male volunteers were studied before, during, and after the 17-day mission and 17 days of -6 degrees head-down-tilt bed rest ...
Oudiz Ronald J - - 2006
In a clinical trial of 178 patients with pulmonary arterial hypertension, treatment improved the 6-minute walk (6MW) distance but not the peak VO2. To clarify this discrepancy, we examined the exercise data from all study sites. Patients received either the endothelin receptor antagonist sitaxsentan or placebo and underwent serial 6MW ...
Osborne Mark A - - 2006
The purpose of this study was to determine whether muscle glycogen reduction prior to exercise would alter muscle fibre recruitment pattern and change either on-transient O2 uptake (VO2) kinetics or the VO2 slow component. Eight recreational cyclists (VO2peak, 55.6 +/- 1.3 ml kg (-1) min(-1)) were studied during 8 min ...
Schmid Jean-Paul - - 2005
BACKGROUND: The protocol and the duration of an exercise test have considerable influence on peak oxygen consumption (VO2). On a bicycle ergometer, the use of a ramp protocol with a target exercise duration of 8 to 12 minutes is recommended to reliably measure maximal oxygen uptake. Because of cardiac denervation, ...
Giardini A - - 2005
The aim of this study was to evaluate the ability to recover from exercise in patients with a Mustard/Senning (M/S) repair for transposition of the great arteries and to identify the major determinants. A total of 40 consecutive patients with a M/S repair at a mean age of 10.0 +/- ...
Guazzi Marco - - 2005
OBJECTIVES: This study sought to define the relative prognostic value of cardiopulmonary exercise testing (CPET) variables in heart failure (HF) patients with preserved versus reduced systolic function. BACKGROUND: Cardiopulmonary exercise testing has an established role in the assessment of patients with systolic heart failure (SHF). Two variables, peak Vo2 and, ...
Takaki Hiroshi - - 2006
OBJECTIVES: At exercise testing with respiratory gas analysis in patients with inducible myocardial ischemia, we have occasionally observed abnormal transient oxygen uptake (VO2) components with a characteristic "Hump"-shaped morphology early after exercise, which may serve as an index for inducible ischemia. We examined this hypothesis in patients with anterior q-wave ...
Pakkala Amrith - - 2005
This study was aimed to determine during exercise the maximum related oxygen transport viz, maximum heart rate (max HR), dyspnoeic index (DI), oxygen pulse (O2 pulse), recovery heart rate in an athletic and a non-athletic group. Both study groups were subjected to graded treadmill exercise testing and pulmonary function test ...
Endo Masako - - 2005
The mechanism that alters the pulmonary VO2 response to heavy-intensity exercise following prior heavy exercise has been frequently ascribed to an improvement in pre-exercise blood flow (BF) or O(2) delivery. Interventions to improve O(2) delivery have rarely resulted in a similar enhancement of VO2. However, the actual limb blood flow ...
Bauer, Timothy Alan
Peripheral arterial disease (PAD) is a manifestation of the systemic disease of atherosclerosis that results in arterial stenoses of the lower extremities. Patients with PAD demonstrate slowed dynamics of pulmonary oxygen uptake (VO2 kinetics) following the onset of exercise and a profound reduction in peak oxygen uptake and work capacity. ...
De Caro E - - 2006
To evaluate cardiopulmonary exercise tolerance in a large cohort of apparently healthy paediatric cancer survivors in order to determine their participation in sporting activities. A total of 84 young (<21 years) asymptomatic childhood cancer survivors, who had been exposed to anthracyclines (mean dose 212 mg/m2) and/or chest irradiation (median dose ...
Budts W - - 2005
OBJECTIVE: In adult patients with repaired tetralogy of Fallot (TF) QRS duration at rest seems to be a predictor of maximal exercise. We examined the relationship between QRS duration during exercise and exercise performance. DESIGN: In 57 consecutive TF patients QRS duration in V1 (ms) was measured at rest, at ...
Austin, Krista Gail
ABSTRACT The primary purpose of this study was to examine the erythropoietic response to intermittent hypoxic exposure (IHE) vs. intermittent hypoxic training (IHT). A secondary purpose was to assess the effects of IHE and IHT on time trial performance (TT), maximal oxygen carrying capacity (VO2max), and submaximal exercise capacity. Six ...
Hill D W - - 2005
AIM: VO2peak can be achieved over the range of intensities that define the severe intensity domain. The purpose of this study was to help characterize the VO2 response during constant-load exercise in this domain. METHODS: Twelve participants performed cycle ergometer tests at 267+/-52 W, 238+/-45 W, and 216+/-37 W, which ...
Astorino T A - - 2005
BACKGROUND: A plateau in oxygen consumption (VO2) is the primary means of confirming that maximal oxygen uptake (VO2max) is attained during incremental exercise to fatigue. However, it is still unresolved what causes expression of a plateau in VO2 at the end of incremental exercise. OBJECTIVES: To elucidate incidence and identify ...
Keslacy S - - 2005
Humoral factors play an important role in the control of exercise hyperpnea. The role of neuromechanical ventilatory factors, however, is still being investigated. We tested the hypothesis that the afferents of the thoracopulmonary system, and consequently of the neuromechanical ventilatory loop, have an influence on the kinetics of oxygen consumption ...
MacPhee Shelley L - - 2005
Six male subjects [23 yr (SD 4)] performed repetitions (6-8) of two-legged, moderate-intensity, knee-extension exercise during two separate protocols that included step transitions from 3 W to 90% estimated lactate threshold (thetaL) performed as a single step (S3) and in two equal steps (S1, 3 W to approximately 45% thetaL; ...
Barrios Carlos - - 2005
STUDY DESIGN: A prospective evaluation of cardiopulmonary tolerance to maximal exercise in adolescent idiopathic scoliosis. OBJECTIVES: To evaluate ventilatory functional restrictions during a maximal exercise tolerance test in idiopathic scoliosis patients with mild and moderate curves and to compare them with the results obtained in healthy adolescents matched in age ...
Dupont Grégory - - 2005
The purpose of this study was to test the hypothesis that subjects having a shorter time constant for the fast component of VO2 kinetics in a transition from rest to constant exercise would maintain their speed for a longer time during repeated sprint exercise (RSE). Eleven male soccer players completed ...
Braun W A - - 2005
The purpose of the study was to evaluate the effects of circuit training (CT) and treadmill exercise performed at matched rates of oxygen consumption and exercise duration on elevated post-exercise oxygen consumption (EPOC) in untrained women, while controlling for the menstrual cycle. Eight, untrained females (31.3 +/- 9.1 years; 2.04 ...
Norman Anne-Caroline - - 2005
Relatively little is known about how excess body mass affects adolescents' capacity to perform sustained exercise. We hypothesized that most of the difficulty that severely overweight adolescents have with sustained exercise occurs because the metabolic costs of moving excess mass result in use of a high proportion of their total ...
Ferreira Leonardo F - - 2005
The kinetic characteristics of muscle capillary blood flow (Qcap) during recovery from exercise are controversial (e.g. one versus two phases). Furthermore, it is not clear how the overall Qcap kinetics are temporally associated with muscle oxygen uptake (VO2m) kinetics. To address these issues, we examined the kinetics of Qcap estimated ...
Hannukainen Jarna C - - 2005
Cross-sectional studies in athletes and untrained subjects suggest that exercise training induces adaptations in cardiac structure and function. However, the role of genetic variation on the results has largely been ignored in these studies. The purpose of this study was to investigate the effects of long-term volitionally increased physical activity ...
Paterson Nicole D - - 2005
It has been suggested that, during heavy-intensity exercise, O(2) delivery may limit oxygen uptake (.VO2) kinetics; however, there are limited data regarding the relationship of blood flow and .VO2 kinetics for heavy-intensity exercise. The purpose was to determine the exercise on-transient time course of femoral artery blood flow (Q(leg)) in ...
Koppo Katrien - - 2005
PURPOSE: To test the hypothesis that the initial O2 uptake kinetics during exercise where the rise in blood flow (and, by implication, O2 delivery) to the working muscles during an abrupt increase in exercise intensity is reduced (i.e., arm exercise performed above the level of the heart) would be faster ...
Kinugawa Shintaro - - 2005
BACKGROUND: We have reported that there is a limitation of exercise capacity in mice with defects in the expression of endothelial nitric oxide (NO) synthase, which is associated with a greater increase in whole-body oxygen consumption (VO2). We hypothesized that in states in which superoxide anion (O2-) is increased, especially ...
Sahlin K - - 2005
We investigated the hypothesis that the pulmonary oxygen uptake (VO2) slow component is related to a progressive increase in muscle lactate concentration and that prior heavy exercise (PHE) with pronounced acidosis alters VO2 kinetics and reduces work efficiency. Subjects (n= 9) cycled at 75% of the peak VO2 (VO2peak) for ...
Liang Michael T C - - 2005
The purpose of this study was to investigate whether a single 1,350-mg dose of Panax notoginseng (PNG) could enhance aerobic capacity, endurance, and mean blood pressure (MAP) in young adults. We randomly assigned 29 untrained adults, aged 20-35 years, to an experimental (EXP, n = 13) or a control (CON, ...
Favier F B - - 2005
Few studies evidenced an enhancement in oxygen uptake (VO2) during submaximal exercise in hyperoxia. This O2 "overconsumption" seems to increase above the lactate threshold. The aim of this study was to determine whether the hyperoxia-induced enhancement in VO2 may be related to a higher metabolism of lactate. Nine healthy males ...
Pianosi P - - 2005
BACKGROUND: Single measurements of peak oxygen uptake (VO2) have been shown to predict mortality in patients with cystic fibrosis (CF) although no longitudinal study of serial measurements has been reported in children. A study was undertaken to determine whether the initial, final, or the rate of fall of forced expiratory ...
Keefer Daniel J - - 2005
Within- and between-day stability in locomotor energy use was quantified in 13 children with hemiplegic cerebral palsy (CP). During testing, subjects were familiarized with the laboratory environment (Session 1), performed three 5 min level treadmill walks (Trials 1-3) at 0.67 m*s(-1) (Session 2), and completed a single 5 min walk ...
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