Search Results
Results 201 - 250 of 1079
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Guelfi Kym J - - 2007
Exercise is generally recommended for individuals with type 1 diabetes mellitus since it is associated with numerous physiological and psychological benefits. However, participation in exercise can also increase the risk of experiencing severe hypoglycaemia, a potentially life-threatening condition, both during exercise and for up to 31 hours of recovery. Fortunately, ...
Sari Ramazan - - 2007
Obese individuals are frequently hyperleptinemic and insulin resistant. Chronic exercise is associated with improvements in plasma leptin level and insulin sensitivity; however, little is known about the acute effect of exercise on these parameters. The aim of this study was to evaluate the acute effect of aerobic exercise on plasma ...
Azevedo John L - - 2007
Exogenous carbohydrate oxidation was assessed in 6 male Category 1 and 2 cyclists who consumed CytoMax (C) or a leading sports drink (G) before and during continuous exercise (CE). C contained lactate-polymer, fructose, glucose and glucose polymer, while G contained fructose and glucose. Peak power output and VO2 on a ...
Baum Klaus - - 2007
Although it is well documented that persons suffering from diabetes type 2 profit from muscular activities, just a negligible amount of patients take advantage of physical exercises. During the last decade, vibration exercise (VE) could be established as an effective measure to prevent muscular atrophy and osteoporosis with low expenditure ...
Wadley Glenn D - - 2007
The purpose of the present study was to determine in human skeletal muscle whether a single exercise bout and 7 days of consecutive endurance (cycling) training 1) increased insulin-stimulated Akt pSer(473) and 2) altered the abundance of the protein tyrosine phosphatases (PTPases), PTP1B and SHP2. In healthy, untrained men (n ...
Chalhoub E - - 2007
A model of reaction and transport in the liver was developed that describes the metabolite concentration and reaction flux dynamics separately within the tissue and blood domains. The blood domain contains equations for convection, axial dispersion, and transport to the surrounding tissue; and the tissue domain consists of reactions representing ...
Shojaee-Moradie F F Department of Diabetes, Endocrinology and Internal Medicine, GKT School of Medicine, King's College London, London, UK. - - 2007
It is not known whether the beneficial effects of exercise training on insulin sensitivity are due to changes in hepatic and peripheral insulin sensitivity or whether the changes in insulin sensitivity can be explained by adaptive changes in fatty acid metabolism, changes in visceral fat or changes in liver and ...
Iscoe Katherine E - - 2006
BACKGROUND: Hypoglycemia is the most common and serious side effect of insulin therapy in type 1 diabetes (T1DM), frequently occurring both during and after vigorous exercise. Late-onset hypoglycemia (LOH) is of great concern, occurring 1-36 h after exercise, often going unnoticed during sleep. Repeated exposure to LOH causes autonomic glucose ...
Ghanassia E - - 2006
OBJECTIVES: Exercise is a recommended treatment for type 2 diabetes but the actual pattern of metabolic adaptation to exercise in this disease is poorly known and not taken in account in the protocols used. Metabolic defects involved in the pathways of substrate oxidation were described in type 2 diabetes. We ...
McMahon Sarah K - - 2007
Exercise increases the risk of hypoglycemia in type 1 diabetes. This study aimed to investigate how the amount of glucose required to prevent an exercise-mediated fall in glucose level changes over time in adolescents with type 1 diabetes. The study took place at a tertiary pediatric referral center. Nine adolescents ...
Cade W Todd WT Department of Medicine, Washington University School of Medicine, 4444 Forest Park Blvd., St. Louis, MO 63108-2212, USA. - - 2007
The protease inhibitor (PI) ritonavir (RTV) has been associated with elevated resting lipolytic rate, hyperlipidemia, and insulin resistance/glucose intolerance. The purpose of this study was to examine relationships between lipolysis and fatty acid (FA) oxidation during rest, moderate exercise and recovery, and measures of insulin sensitivity/glucose tolerance and fat redistribution ...
Gill Jason M R - - 2007
Prior moderate exercise has been shown consistently to reduce postprandial triglyceride (TG) concentrations in non-diabetic adults, but its effects in men with type 2 diabetes are not known. This study aimed to determine the effect of moderate exercise on postprandial metabolism in men with type 2 diabetes. Ten middle-aged men ...
Hasson Rebecca E - - 2006
African Americans are more insulin resistant than Caucasians. A single bout of moderate-intensity exercise reduces insulin resistance in sedentary Caucasian individuals. The impact of a single bout of exercise on insulin resistance has never been studied in African Americans. The purpose of this experiment was to evaluate the impact of ...
Smirnova I V - - 2006
The focus of this study was to determine whether minimal levels of exercise could halt the formation of diabetes-induced heart pathology. Seven-week-old male rats were divided into four groups: sedentary nondiabetic, exercise-trained non-diabetic, sedentary diabetic and exercise-trained diabetic. Individualised exercise programmes were based on the animal's tolerance, and continued for ...
Brassard Patrice - - 2006
Conflicting results exist regarding the impact of glycemic control on peak oxygen uptake (VO2peak) in subjects with type 2 diabetes mellitus. The influence of glycemic control on submaximal oxygen uptake (VO2) in these subjects is unknown. The aim of this study was to evaluate the impact of fasting blood glucose ...
Petersen A M W - - 2006
Regular exercise offers protection against all cause mortality and there is evidence from randomised intervention studies that physical training is effective as a treatment in patients with chronic heart diseases, type 2 diabetes and symptoms related to the metabolic syndrome. Chronic diseases such as cardiovascular disease, type 2 diabetes and ...
Treiber, Kimberly Hoffer
Glucose is a fundamental energy source, the utilization and regulation of which impacts exercise performance and health. These studies have used modeling techniques to evaluate glucose kinetics and dynamics in equids and developed tests to evaluate the status of glucose metabolism. In Part I, 12 exercise-trained Arabians underwent insulin-modified FSIGT ...
De Filippis Elena - - 2006
The present study was undertaken to determine whether improved vasodilatory function accompanies increased insulin sensitivity in overweight, insulin-resistant subjects (OW) and type 2 diabetic patients (T2DM) who participated in an 8-wk exercise training regimen. Before and after training, subjects had euglycemic clamps to determine insulin sensitivity. Brachial artery catheterization was ...
Lang James A - - 2006
The purpose of this study was to determine the effects of exercise intensity on active and passive intestinal glucose absorption. Eight trained runners (age = 23 +/- 2 y; VO2max = 62.1 +/- 5.8 mL x kg(-1) x min(-1)) performed a 1 h resting experiment and three 1 h treadmill ...
- - 2006
Strategies for preventing hypoglycemia during exercise in children with type 1 diabetes have not been well studied. The Diabetes Research in Children Network (DirecNet) Study Group conducted a study to determine whether stopping basal insulin could reduce the frequency of hypoglycemia occurring during exercise. Using a randomized crossover design, 49 ...
Zhang John Q - - 2006
We examined the effect of exercise on postprandial lipemia (PPL) and insulin resistance in individuals with metabolic syndrome. Subjects were 10 hypertriglyceridemia (HTG) males with insulin resistance [age = 40.1 +/- 2.2 years, body weight = 96.3 +/- 3.3 kg, fasting triglyceride (TG) = 263 +/- 25 mg/dl, VO(2)max = ...
Ropelle Eduardo R - - 2006
Lifestyle interventions including exercise programmes are cornerstones in the prevention of obesity-related diabetes. In this study, we demonstrate that a single bout of exercise inhibits high-fat diet-induced insulin resistance. Diet-induced obesity (DIO) increased the expression and activity of the protein tyrosine phosphatase 1B (PTP1B) and attenuated insulin signalling in gastrocnemius ...
Sompol Sanguanrungsirikul, 1959-
Thesis (M.Sc.)--Chulalongkorn University, 2004
Fayolle C - - 2006
AIM: The GlucoDay allows continuous glucose monitoring by subcutaneous microdialysis in sedentary conditions. To validate it when glycaemia may undergo rapid and dramatic changes, we investigated its accuracy during two exercise sessions with markedly different glucose disposal rates. METHODS: Nine male diabetic patients, aged 32-61, treated by insulin pumps, first ...
Chang Full-Young - - 2006
The present study was to determine the effect of strenuous exercise on glucose utilization, lactate accumulation and small intestinal transit (SIT). In strenuous exercises, rats would be put on the runway of a moving treadmill for a one-hour compulsive running. Rats first performed running treadmill for 45 min. After orogastric ...
Haider Dominik G - - 2006
CONTEXT: Exercise training exerts beneficial effects on metabolic and vascular risk factors in patients with type 1 diabetes mellitus (T1DM). It is unknown whether training also influences concentrations of visfatin, a novel insulin-mimetic adipocytokine. OBJECTIVES: In this study, we have investigated whether plasma visfatin concentrations are altered by training in ...
Stewart-Hunt L - - 2006
REASONS FOR PERFORMING STUDY: Increased insulin sensitivity occurs after a period of exercise training, but the mechanisms underlying this training-associated increase in insulin action have not been investigated. OBJECTIVE: To examine the effects of short-term endurance training (7 consecutive days) and a subsequent period of inactivity (5 days) on whole ...
Kim Junghoon - - 2006
The purpose of this study was to characterize the effects of prior swim exercise on glucose uptake in isolated skeletal muscles of mice. Male and female mice (C57BL/6) performing 180 min of swimming had significantly decreased glycogen concentration compared to resting controls in soleus, extensor digitorum longus (EDL), and epitrochlearis ...
Choi Soo Bong - - 2006
Long-term dexamethasone (DEX) treatment is well known for its ability to increase insulin resistance in liver and adipose tissues leading to hyperinsulinemia. On the other hand, exercise enhances peripheral insulin sensitivity. However, it is not clear whether DEX and/or exercise affect beta-cell mass and function in diabetic rats, and whether ...
Howlett Kirsten F - - 2006
Exercise increases skeletal muscle insulin action but the underlying mechanisms mediating this are equivocal. In mouse skeletal muscle, prior exercise enhances insulin-stimulated insulin receptor substrate-2 (IRS-2) signaling (Diabetes 2002;51:479-83), but it is unknown if this also occurs in humans. Hyperinsulinemic-euglycemic clamps were performed on 7 untrained males at rest and ...
Vickers Kristin S - - 2006
OBJECTIVE: To examine the association between depressive symptoms and exercise-related variables among patients with type 2 diabetes. METHODS: Surveys were completed by 207 primary care patients diagnosed with type 2 diabetes (52% female; 95% white; mean age = 63 years). Multiple linear regression analyses were conducted. RESULTS: Lower use of ...
Wagner Henrik - - 2006
OBJECTIVE: The effect of exercise training and acarbose on glycemic control, insulin sensitivity, and phenotype was investigated in mild type 2 diabetes. RESEARCH DESIGN AND METHODS: Sixty-two men and women with type 2 diabetes were randomized to 12 weeks of structured exercise training with or without acarbose treatment or to ...
Yang Ai-Lun - - 2006
Improved vasorelaxant response is one of the beneficial effects of exercise training on vascular function. The mechanism for this response is, however, poorly understood. The aim of this study was to investigate the effects of exercise training on insulin-induced and insulin-like growth factor-1 (IGF-1)-induced vasorelaxation. Fourteen 6-week-old male Wistar rats ...
Hamada Taku - - 2006
The primary purpose of this study was to determine the effect of prior exercise on insulin-stimulated glucose uptake with physiological insulin in isolated muscles of mice. Male C57BL/6 mice completed a 60-min treadmill exercise protocol or were sedentary. Paired epitrochlearis, soleus, and extensor digitorum longus (EDL) muscles were incubated with ...
Nielsen Paul J - - 2006
This review applied meta-analytic procedures to integrate primary research that examined exercise fitness outcomes among adults with type 1 or type 2 diabetes. We used extensive literature searching strategies to locate published and unpublished intervention studies that tested exercise interventions. We conducted meta-analytic procedures using both fixed- and random-effects models. ...
Englert Virginia - - 2006
BACKGROUND: Acute exercise is associated with increased insulin sensitivity characterized by increased insulin-induced glucose transport for periods of up to 48 h after the bout of exercise. This suggests that the glycemic response to a meal may be altered by prior exercise. OBJECTIVE: We tested the hypothesis that the glycemic ...
Horton Tracy J - - 2006
As exercise can improve the regulation of glucose and carbohydrate metabolism, it is important to establish biological factors, such as sex, that may influence these outcomes. Glucose kinetics, therefore, were compared between women and men at rest, during exercise, and postexercise. It was hypothesized that glucose flux would be significantly ...
Brassard Patrice - - 2006
Subjects with Type 2 diabetes without cardiovascular disease have a reduced exercise capacity compared with nondiabetic subjects. However, the mechanisms responsible for this phenomenon are unknown. The purpose of this study was to evaluate the impact of exercise systolic blood pressure (SBP) response on diverse exercise tolerance parameters in Type ...
Tsai Yi-Ming - - 2006
Serum dehydroepiandrosterone sulfate (DHEA-S) concentration is known to be associated with the whole-body insulin sensitivity. The main purpose of the study was to investigate the effect of resistance exercise on DHEA-S concentration during a 72 h post-exercise recovery, and its relation to glucose tolerance and insulin sensitivity. Morning fasted serum ...
Sandoval Darleen A - - 2006
Type I diabetes mellitus patients who tightly control blood glucose levels toward normal have increased frequency of hypoglycemia, a major barrier to physical activity. This article presents the hypothesis that dysfunctional autonomic regulation of metabolism after recent bouts of exercise or hypoglycemia contributes to exercise-induced hypoglycemia in these patients.
Hickner Robert C - - 2006
PURPOSE: Oral L-arginine supplementation has been shown to improve treadmill time to exhaustion and resting insulin sensitivity in individuals with peripheral vascular disease and type 2 diabetes, respectively. Furthermore, L-citrulline supplementation increases plasma L-arginine concentration to a level higher than that achieved by oral L-arginine supplementation. The purpose of this ...
Kalmár Katalin - - 2006
The present study examines the differences in gastrointestinal hormone production at 3 different reconstruction types after total gastrectomy. Total gastrectomy causes significant weight loss, mainly due to a reduced caloric intake probably because of a lack of initiative to eat or early satiety during meals. Behind this phenomenon a disturbed ...
Chang Shih-Pei - - 2006
Aerobic exercise, including treadmill running has been widely used to treat insulin resistance and type 2 diabetes. We studied the effects of endurance training on gene expression of adiponectin receptor 1 (AdipoR1) in skeletal muscle of obese Zucker rats: the 8-week moderate exercise program consisted of treadmill running at 20 ...
Jamurtas A Z - - 2006
The purpose of this study was to investigate the effects of a submaximal aerobic exercise bout on adiponectin and resistin levels as well as insulin sensitivity, until 48 h post-exercise in healthy overweight males. Nine subjects performed an exercise bout at an intensity corresponding to approximately 65% of their maximal ...
Coker Robert H - - 2006
PURPOSE: Although data suggest that physical activity is associated with decreased insulin resistance, recommendations for exercise training are not specific for age or level of obesity. Therefore, we examined the influence of moderate-intensity (50% of VO2max) exercise training (MI) versus high-intensity (75% of VO2max) exercise training (HI) on insulin-stimulated glucose ...
Bussau Vanessa A - - 2006
OBJECTIVE: To investigate whether a short maximal sprint can provide another means to counter the rapid fall in glycemia associated with moderate-intensity exercise in individuals with type 1 diabetes and therefore decrease the risk of early postexercise hypoglycemia. RESEARCH DESIGN AND METHODS: In the study, seven male subjects with type ...
Hayashi, Tatsuya
HAYASHI, T., HIGAKI, Y. and L J GOODYEAR.,Exercise Regulation of Skeletal Muscle Glucose Transport. Adv. Exerc. Sports Physiol., Vol.5, No.1 pp1-8, 1999. Over the past several years considerable progress has been made in understanding the molecular mechanisms for the effect of exercise on glucose ...
Ohmori, Kazunobu
OHMORI, K., KUNO, S., KIMURA, Y., MIZUNO, M., NAKAMURA, Y., MURAOKA, I., OHTA, F., MISHIMA, M., TOYAMA, H. and SENDA, M., Assessment of Regional Change of Glucose Metabolism after High-Intensity Exercise in Exercised Muscle using Positron Emission. Adv. Exerc. Sports Physiol., Vol.6, No.3 pp81-84, 2000. This investigation was conducted to ...
Galassetti Pietro - - 2006
Hypoglycemia frequently occurs during or after exercise in intensively treated patients with type 1 diabetes mellitus (T1DM), but the underlying mechanisms are not clear. In both diabetic and nondiabetic subjects, moderate hypoglycemia blunts counterregulatory responses to subsequent exercise, but it is unknown whether milder levels of hypoglycemia can exert similar ...
Winnick, Jason J
Background: Previous investigations have examined the effect of aerobic exercise training on peripheral glucose uptake (PGU) and endogenous glucose production (EGP) in humans with type 2 diabetes mellitus (DM). These studies often use lengthy training durations that improve both body fat levels and maximal oxygen consumption. Improvements to either of ...
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