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Silveira Leonardo L Postgraduate Program in Respiratory Sciences, Federal University of Rio Grande do Sul (UFRGS), Novo Hamburgo, - - 2014
Reduced fat-free mass (FFM), a common finding in chronic obstructive pulmonary disease (COPD), may indirectly impact peak exercise capacity through a greater level of pulmonary hyperinflation. We aimed to investigate if FFM index (FFM/squared height) impacts exercise induced dynamic hyperinflation in COPD patients. Fifty-four patients with moderate-to-very severe COPD performed ...
Jolley Caroline J CJ King's College London Division of Asthma, Allergy and Lung Biology, King's College London School of Medicine, King's Health Partners, London, UK - - 2014
The aim of this study was to test the hypothesis that neural respiratory drive, measured using diaphragm electromyogram (EMGdi) activity expressed as a percentage of maximum (EMGdi%max), is closely related to breathlessness in chronic obstructive pulmonary disease. We also investigated whether neuroventilatory uncoupling contributes significantly to breathlessness intensity over an ...
Leung Nelson N Division of Nephrology and Hypertension; Division of - - 2014
A 74-year-old white male, lifetime non-smoker underwent evaluation for a three year history of dyspnea. Patient was a former professional athlete who was still working full time. He had remained physically fit and was able to perform his regular exercise routine which included 25 minutes on the elliptical machine plus ...
Dowman Leona L Department of Physiotherapy, La Trobe University, Melbourne, Australia, - - 2014
Interstitial lung disease (ILD) is characterised by reduced functional capacity, dyspnoea and exercise-induced hypoxia. Pulmonary rehabilitation, an intervention that includes exercise training, is beneficial for people with other chronic lung conditions; however its effects in ILD have not been well characterised. • To determine whether pulmonary rehabilitation in patients with ...
Pradella Cristiane O CO Pulmonary Rehabilitation Center, - - 2014
The aim of this study was to develop an efficient, low-cost, home-based pulmonary rehabilitation program and to evaluate the impact of the program on exercise as measured by the 6-min walk test (6MWT) and treadmill endurance test. Twenty-nine subjects with COPD (FEV1 = 62.4 ± 10.7% of predicted, 62.4 ± ...
Vernillo G G Department of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy; CeRiSM, Research Center "Sport, Mountain and Health", University of Verona, Rovereto, - - 2014
This study aimed to assess the effects of an extreme mountain ultramarathon (MUM, 330 km, 24 000 D+) on lung function. Twenty-nine experienced male ultramarathon runners performed longitudinally [before (pre), during (mid), and immediately after (post) a MUM] a battery of pulmonary function tests. The tests included measurements of forced vital capacity, ...
Hassel Erlend - - 2014
BackgroundRight ventricular dysfunction in COPD is common, even in the absence of pulmonary hypertension. The aim of the present study was to examine the effects of high intensity interval training (HIIT) on right ventricular (RV) function, as well as pulmonary blood vessel remodeling in a mouse model of COPD.Methods42 female ...
Wibmer Thomas T Department of Internal Medicine II, University Hospital of Ulm, Ulm, Germany. - - 2014
There is growing evidence that exercise-induced variation in lung volumes is an important source of ventilatory limitation and is linked to exercise intolerance in COPD. The aim of this study was to compare the correlations of walk distance and lung volumes measured before and after a 6-min walk test (6MWT) ...
Neder J Alberto JA 1Respiratory Investigation Unit, Queen's University & Kingston General Hospital , Kingston, Ontario , - - 2014
Abstract The difference between total lung capacity (TLC) by body plethysmography and alveolar volume (VA) from the single-breath lung diffusing capacity measurement provides an index of ventilation distribution inequalities in COPD. The relevance of these abnormalities to dyspnea and exercise intolerance across the continuum of disease severity remains unknown. Two-hundred ...
Fuschillo Salvatore S Pulmonary Rehabilitation Unit - - 2014
Patients with kyphoscoliosis and severe respiratory impairment frequently experience reduction in exercise tolerance, limitation in daily life activities, and deterioration in health-related quality of life (HRQOL). Noninvasive ventilation (NIV) as an add-on treatment to long-term oxygen therapy (LTOT) was shown to improve symptoms and HRQOL in these patients. Pulmonary rehabilitation ...
van Gestel Arnoldus J R AJ Department of Pulmonary Medicine, Cantonal Hospital, St. Gallen, - - 2014
Background: The 6-min walk test (6MWT) is representative of daily life activities and reflects the functional capacity of patients with chronic obstructive pulmonary disease (COPD). Information on the cardiopulmonary and gas exchange responses to the 6MWT is limited. Objectives: We aimed to analyze the breath-by-breath cardiopulmonary and gas exchange responses ...
López-García A A Department of Physiotherapy, Faculty of Physiotherapy, University of A Coruña (UDC), Spain - - - 2014
Muscular training is the corner stone of pulmonary rehabilitation programs. To evaluate the effects of a muscular training program -- carried out on COPD subjects with antecedents of moderate or severe exacerbation -- on exercise tolerance, Health Related Quality of Life (HRQoL) and illness prognosis. A quasi--experimental study. University Hospital ...
O'Donnell Denis E DE Queen's University and Kingston General Hospital, Kingston, Ontario, Canada;1Queen's University and Kingston General Hospital, Kingston, Ontario, Canada. - - 2014
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide and, although it is a preventable and treatable disease, it often remains undiagnosed in patients with mild disease. It is now evident that pathologic changes and physiologic impairment start early in disease progression, and even patients ...
Yeh Gloria Y - - 2014
Chronic obstructive pulmonary disease (COPD) is a chronic, progressively debilitating condition that is prevalent in the US and worldwide. Patients suffer from progressive dyspnea and exercise intolerance. Physical exercise is beneficial, but conventional pulmonary rehabilitation programs are underutilized. There remains a need for novel interventions that improve symptoms, quality-of-life, and ...
Guenette Jordan A JA Respiratory Investigation Unit, Queen's University and Kingston General Hospital, Kingston, ON, Canada Dept of Physical Therapy, University of British Columbia, Vancouver, BC, Canada Centre for Heart Lung Innovation, Providence Health Care Research Institute, University of British Columbia, St. Paul's Hospital, Vancouver, BC, - - 2014
The purpose of this study was to determine if a dissociation existed between respiratory drive, as estimated by diaphragmatic electromyography (EMGdi), and its pressure-generating capacity during exercise in mild chronic obstructive pulmonary disease (COPD) and whether this, if present, had negative sensory consequences. Subjects meeting spirometric criteria for mild COPD ...
Ho Jen-Yu JY a Department of Athletic Performance , National Taiwan Normal University , Taipei , - - 2014
This study examined hormonal responses to low-intensity resistance exercise under mild simulated hypoxia. Ten resistance untrained men performed five sets of 15 repetitions of squat exercise at 30% of 1RM under normobaric hypoxia (FiO2 = 15%) and normoxia in a cross-over and counter-balanced design. Blood lactate (LAC), growth hormone (GH), ...
Eliakim A A 1Child Health & Sports Center, Pediatric Department, Meir Medical Center, Sackler School of Medicine, Tel-Aviv University, Israel. 2The Zinman College of Physical Education and Sport Sciences, Wingate Institute, Netanya, - - 2014
Exercise-associated effects on the GH→IGF-I axis were studied, mainly following aerobic exercise. We determined the gender effect on the GH→IGF-I axis response to a standard all-out Wingate anaerobic test (WAnT) in healthy active young adult males and females (males=12, females=16, age range: 24-34 years). Blood samples for GH and IGF-I, ...
JanukonytÄ— J J Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark. Electronic address: - - 2014
Diurnal variation in serum growth hormone (s-GH) levels after exogenous GH delivery has previously been reported in patients with no endogenous GH secretion. Changes in postural position or physical activity, leading to changes in blood flow and/or lymphatic drainage may be underlying explanations. The primary aim of this study is ...
Moeller Chad R CR Arizona Diamondbacks Baseball Club, - - 2014
Context :  Alterations in scapular muscle activation, which are common with glenohumeral (GH) injuries, affect stability and function. Rehabilitation aims to reestablish activation between muscles for stability by progressing to whole-body movements. Objective :  To determine scapular muscle-activation ratios and individual muscle activity (upper trapezius [UT], middle trapezius [MT], lower ...
Voss Sven Christian SC Anti-Doping Lab Qatar, PO Box 27775, Doha, Aspire Zone, Doha, - - 2014
The major objective of this study was to investigate the effects of several days of intense exercise on the growth hormone marker approach to detect doping with human growth hormone (hGH). In addition we investigated the effect of changes in plasma volume on the test. Fifteen male athletes performed a ...
Andrews Leanne L School of Health and Human Sciences, University of Essex, Wivenhoe Park, Colchester CO4 3SQ, UK. Electronic address: - - 2014
To investigate changes and differences in patient outcomes over time for 6, 7 and 8 week pulmonary rehabilitation programmes in order to identify optimal duration. Community based pulmonary rehabilitation programmes in the East of England. In total 363 participants completed one of the three pulmonary rehabilitation programmes. Patients with a ...
Budnar Ronald G RG Jr 1Applied Physiology Laboratory Department of Kinesiology, Health Promotion and Recreation University of North Texas Denton, TX 76203 2Department of Biological Sciences University of North Texas Denton, TX - - 2014
The purpose of this investigation was to examine the acute hormonal response to the kettlebell swing exercise. Ten recreationally resistance trained men (24±4 y, 175±6 cm, 78.7±9.9 kg) performed 12 rounds of 30 seconds of 16 kg kettlebell swings alternated with 30 seconds of rest. Blood samples were collected before ...
Rezaee S S Department of Physiotherapy Tarbiat Modares University, Tehran, Iran - - - 2014
Aim: This study investigated the influence of resistance (R) following endurance (E) exercise or ER on acute hormonal responses, such as growth hormone (GH), total testosterone (TT), free testosterone (FT), IGF-1, and cortisol. Methods: Ten healthy young men with an average age of 23.9 years (±0.7 y), a height of ...
Ackerman James - - 2014
Antioxidant supplementation is known to increase human endogenous antioxidant (AOX) capacity providing a means of blunting exercise induced reactive oxygen species (ROS). The purpose of this study was to compare the effects of a single acute dose of an AOX (vs blinded placebo) on muscle contractile performance and hormonal responses ...
Nindl Bradley C BC 1Military Performance and 2Military Nutrition Divisions, U.S. Army Research Institute of Environmental Medicine, Natick, - - 2014
The pulsatile secretion pattern of growth hormone (GH) is an important parameter of GH action at peripheral tissues and more information is needed on how exercise impacts GH secretion. This study hypothesized that both aerobic and resistance exercise would exhibit dose-response relationships with respect to exercise duration and 20-h post-exercise ...
da Silva Davi Vieira Teixeira DV Chemistry Institute, Federal University of Rio de Janeiro, Rio de Janeiro, - - 2014
Nutritional supplements based on the amino acid L-arginine have been hypothesized to improve exercise performance by increasing levels of insulin and growth hormone (GH). Changes of these parameters in response to L-arginine supplementation may clarify the mechanisms underlying its putative physiological effects on physical performance. The aim of the study ...
Galy Olivier O Laboratory ACTES, (EA 3596: Department of Physiology), Faculty of Physical Activity and Sports, University of Guadeloupe, Pointe à Pitre, France; Laboratory CNEP (EA 4242), University of New Caledonia, Nouméa, New - - 2014
Growth hormone (GH) may stimulate water loss during exercise by activating sweating. This study investigated GH secretion and water loss during sequential cycling and running, taking postural changes into account. The two exercise segments had similar durations and were performed at the same relative intensity to determine their respective contributions ...
El Kafy Ehab Mohamed Abd EM Department of Physical Therapy for Disturbances of Growth and Developmental Disorders in Children and Its Surgery (Dr Kafy), Faculty of Physical Therapy, Cairo University, Cairo, Egypt; Physical Therapy Department (Drs Kafy and Helal), Faculty of Applied Medical Sciences, Umm Al Qura University, Makkah, Saudi - - 2014
To examine effects of a rowing exercise regimen versus a chest physical therapy program on pulmonary function in children with Down syndrome. Twenty-nine participants of both sexes, between 8 to 12 years of age, participated in this study. They were assigned randomly into 2 study groups. The first group (A) ...
Osterling Kristin K School of Physiotherapy, Dalhousie University, Halifax, NS, - - 2014
The objective of this systematic review was to determine whether people with moderate to severe COPD who are participating in pulmonary rehabilitation and exercising at high intensity demonstrate the changes in ventilatory parameters that are associated with decreased dyspnea. The authors searched EMBASE, The Cochrane Library, and CINAHL databases up ...
Trilk Jennifer L JL Exercise is Medicine Education Committee, Assistant Professor, Department of Biomedical Sciences, University of South Carolina School of Medicine Greenville, Greenville, South Carolina, - - 2013
Educating medical students and other health professionals in training on the importance of healthy lifestyles for prevention and treatment of disease is essential to transforming healthcare. At the University of South Carolina School of Medicine Greenville (USC SOM Greenville), we are incorporating the 'Exercise is Medicine' Knowledge, Skills and Abilities ...
Shaner Aaron A - - 2013
Resistance exercise can acutely increase concentrations of circulating neuroendocrine factors, but the effect of mode on this response is not established. The purpose of this study was to examine the effect of resistance exercise selection on the acute hormonal response using similar lower-body multi-joint movement free weight and machine weight ...
Forbes Scott C - - 2013
Acute resistance exercise and L-arginine have both been shown to independently elevate plasma growth hormone (GH) concentrations; however, their combined effect is controversial. The purpose was to investigate the combined effects of resistance exercise and L-arginine supplementation on plasma L-arginine, GH, GH secretagogues, and IGF-1 in strength trained participants. Fourteen ...
Alvares Thiago Silveira TS Nucleus of Basic Nutrition and Dietetics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil; Department of Biochemistry, Chemistry Institute, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil. Electronic address: - - 2014
It has been hypothesized that l-arginine improves exercise performance by increasing nitric oxide synthesis and levels of insulin and growth hormone (GH). Metabolic and hormonal responses to chronic l-arginine supplementation may clarify the mechanisms underlying its putative physiologic effects on physical performance. Therefore, the aim of this study was to ...
Oöpik Vahur - - 2013
The major objective of this study was to elucidate the effect of heat acclimation on blood growth hormone (GH) response to moderate intensity exhausting exercise in the heat. In addition, the potential relationship between inter-individual differences in GH response to exercise and variability in exercise-induced sweat loss was investigated. Twenty ...
Kraemer William J - - 2013
The anterior pituitary gland (AP) increases growth hormone (GH) secretion in response to resistance exercise (RE), but the nature of AP adaptations to RE is unknown. We examined the effects of RE on regional AP somatotroph GH release, structure, and relative quantity. Thirty-six Sprague-Dawley rats were assigned to one of ...
Yardley Jane E JE a Human and Environmental Physiology Research Unit, Montpetit Hall, University of Ottawa, Ottawa, ON K1N 6N5, - - 2014
We compared growth hormone (GH) and plasma glucose (PG) levels in type 1 diabetic individuals performing aerobic before resistance exercise (AR) to when resistance exercise was performed first (RA). In AR, GH secretion declined in late exercise while it rose throughout exercise in RA, resulting in higher GH in RA ...
Thomas Gwendolyn A - - 2013
Growth hormone (GH) is regulated, suppressed and stimulated by numerous physiological stimuli. However, it is believed that obesity disrupts the physiological and pathological factors that regulate, suppress or stimulate GH release. Pulsatile GH has been potently stimulated in healthy subjects by both aerobic and resistance exercise of the right intensity ...
Sartorio A - - 2013
Repeated bouts of GH-releasing stimuli (both pharmacological and physiological, such as aerobic exercise) at 2-h intervals are associated with a blunting of somatotropic responsiveness in normal adults, while a persistent GH responsiveness to consecutive stimuli is reported to occur in children and adolescents. Recently, a single bout of respiratory muscle ...
Giunta M - - 2013
In recent years, whole body vibration (WBV) has become an efficient complement or alternative to resistance training. Very limited data on the effects of different WBV protocols on anabolic hormones are available. In this study, we compared the growth hormone (GH), blood lactate (LA), and cortisol responses to different protocols ...
Girman Julia C JC a Department of Exercise Science and Sports Studies , Springfield College , Springfield , MA , - - 2014
Abstract Limited research exists on rest-pause or cluster-set (CS) protocols. Acute effects of a traditional set (TS) and CS protocols of resistance exercise on serum growth hormone (GH), cortisol (C), blood lactate (BL), countermovement vertical jump (CMVJ) and standing long jump (SLJ) were compared. Eleven resistance-trained males (22.9±2.6 year; 176.9±10.6 ...
Myers Valerie H VH Pennington Biomedical Research Center, Baton Rouge, Lousiana, USA. - - 2013
To establish whether exercise improves quality of life (QOL) in individuals with type 2 diabetes and which exercise modalities are involved. Health Benefits of Aerobic and Resistance Training in individuals with type 2 Diabetes (HART-D; n = 262) was a 9-month exercise study comparing the effects of aerobic training, resistance ...
Simão Roberto - - 2013
The aim of this study was to examine acute hormonal responses after different sequences of an upper-body resistance-exercise session. Twenty men completed 2 sessions (3 sets; 70% 1-repetition maximum; 2 min passive rest between sets) of the same exercises in opposite sequences (larger to smaller vs. smaller to larger muscle-group ...
Curzi D D Carlo Bo University of Urbino. - - 2013
Myotendinous junctions (MTJs) are specialized sites on the muscle surface where forces generated by myofibrils are transmitted across the sarcolemma to the extracellular matrix. At the ultrastructural level, the interface between the sarcolemma and extracellular matrix is highly folded and interdigitated at these junctions. In this study, the effect of ...
Mohammadizadeh Mahmoud Asle MA Department of Sport Physiology, School of Physical Education & Sport Science, Shahid Chamran University of Ahwaz - - - 2013
Overweight and obese children are at increased risk of a wide range of health conditions including respiratory diseases. In addition, inactivity can decrease pulmonary function. This study assessed the effect of obesity and inactivity on pulmonary function impairment in adolescents. This study was conducted on 80 adolescents. Subjects were divided ...
Apicella Jenna M - - 2012
Our aim was to examine the effect of betaine supplementation on selected circulating hormonal measures and Akt muscle signaling proteins after an acute exercise session. Twelve trained men (age 19.7 ± 1.23 years) underwent 2 weeks of supplementation with either betaine (B) (1.25 g BID) or placebo (P). Following a 2-week washout period, subjects underwent ...
Stokes Keith A - - 2012
Exercise is a potent stimulus for release of growth hormone (GH), cortisol, testosterone and prolactin, and prolonged exercise inhibits insulin secretion. These responses seem to be specific to the type of exercise but this has been poorly characterised primarily because they have not been compared during exercise performed by the ...
Zebrowska A - - 2012
The study aimed at evaluating changes in plasma levels of insulin-like growth factor 1 (IGF-1), insulin-like growth factor binding protein-3 (IGFBP-3), testosterone, growth hormone (GH), cortisol, and insulin in resistance-trained male athletes with (n=9) and without (n=9) left ventricular hypertrophy (LVH) in response to eccentric (ECC) and concentric (CON) arm ...
Patterson Stephen D - - 2012
It has been suggested that circulating hormones and cytokines are important in the adaptive response to low-load resistance training (LLRT) with blood flow restriction (BFR); however, their response following this type of training in older men is unclear. Seven healthy older men (age 71.0 ± 6.5 year, height 1.77 ± 0.05 m, body mass 80.0 ± 7.5 kg; mean ± SD) ...
Hamouti Nassim - - 2013
Blood serum osmolality (S (OSM)) is the gold standard to assess body fluid balance. Urine specific gravity (U (SG)) is also a body fluid balance index but it is not invasive. However, U (SG) capability to detect the minimal level of dehydration that affects athletic performance (i.e., 2 %) remains ...
Kamijo Yoshi-Ichiro - - 2012
We examined whether carbohydrate in beverages accelerated fluid retention during recovery from thermal and exercise-induced dehydration and whether it was caused in part by an enhanced renal Na(+) reabsorption rate due to insulin secretion. After dehydrating by ~2.3% body weight by exercise in a hot environment, seven young men underwent ...
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