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Pellegrino Riccardo Giovanni RG Allergologia e Fisiopatologia Respiratoria - - 2014
Current guidelines recommend severity of chronic obstructive pulmonary disease be graded using forced expiratory volume in 1 s (FEV1). But this measurements is biased by thoracic gas compression depending on lung volume and airflow resistance. The aim of this study was to test the hypothesis that the effect of thoracic ...
Elbehairy Amany F - - 2014
Smokers with persistent cough and sputum production [chronic bronchitis (CB)] represent a distinct clinical phenotype, consistently linked to negative clinical outcomes. However, the mechanistic link between physiological impairment, dyspnea and exercise intolerance in CB has not been studied, particularly in those with mild airway obstruction. We therefore compared physiological abnormalities ...
Emerson Sam R SR Departments of 1Kinesiology and 2Human Nutrition, Kansas State University, Manhattan, - - 2014
We recently reported a high prevalence of expiratory flow limitation (EFL) independent of sex in prepubescent children that exceeds the prevalence reported in adults. It is unknown how trans-pubertal maturation and growth affect pulmonary function, specifically EFL, during exercise. The purpose of this longitudinal study was to investigate the changes ...
Silveira Leonardo L Postgraduate Program in Respiratory Sciences, Federal University of Rio Grande do Sul (UFRGS), Novo Hamburgo, - - 2014
Reduced fat-free mass (FFM), a common finding in chronic obstructive pulmonary disease (COPD), may indirectly impact peak exercise capacity through a greater level of pulmonary hyperinflation. We aimed to investigate if FFM index (FFM/squared height) impacts exercise induced dynamic hyperinflation in COPD patients. Fifty-four patients with moderate-to-very severe COPD performed ...
Rosato Edoardo E Department of Clinical Medicine, Clinical Immunology Unit-Scleroderma Centre, Sapienza University of Rome, Rome, Italy. - - 2014
In systemic sclerosis (SSc) patients pulmonary vasculopathy (PV) is present in the early stage of disease and impairs dilation of affected pulmonary blood vessels, impeding pulmonary blood flow during exercise. Abnormal gas exchange findings were early investigated by cardiopulmonary exercise test (CPET). A total of 34 female and 6 male ...
Caminiti Giuseppe G Department of Medical Sciences, Cardiovascular Research Unit, San Raffaele IRCCS, Rome, Italy (Dr Caminiti); Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele Pisana, Rome, Italy (Dr Cardaci, Dr Conti, Dr Battaglia, Mr D'Antoni, and Dr Volterrani); and Dipartimento di Medicina Fisica e Riabilitazione, Università Tor Vergata, Rome, Italy (Mr - - 2014
To evaluate the impact of right ventricular dysfunction on exercise tolerance and potential changes resulting from exercise training in patients with chronic obstructive pulmonary disease (COPD) undergoing pulmonary rehabilitation. Subjects were 44 patients with a history of symptomatic (Global Initiative for Chronic Obstructive Lung Disease classes 2-4) COPD attending a ...
Neder J Alberto JA Respiratory Investigation Unit and Laboratory of Clinical Exercise Physiology, Queen's University and Kingston General Hospital, Kingston, ON, Canada Clinical Exercise Physiology Unit (SEFICE), Division of Respirology, Federal University of Sao Paulo, Sao Paulo, - - 2014
Ventilatory inefficiency during exercise is a key pathophysiological feature of chronic obstructive pulmonary disease. Currently, it is unknown how this physiological marker relates to clinically relevant outcomes as resting ventilatory impairment progresses across disease stages. Slope and intercept of the linear region of the ventilation-carbon dioxide output relationship and the ...
LeGear Tyler T Department of Physical Therapy/University of British Columbia, Canada. - - 2014
The chronic obstructive pulmonary disease (COPD) population can experience lower activity and fitness levels than the non-COPD population. The Nintendo Wii may be an appropriate at- home training device for the COPD population which could be used as a supplement for a pulmonary rehabilitation program. This study was a randomized, ...
Kern Lukas - - 2014
The 6-Minute Walk Test (6MWT) is representative of daily-life activities and reflects the functional capacity of patients. The change of oxygen uptake (VO2) in the initial phase of low-intensity exercise (VO2 kinetics) can be used to assess submaximal exercise performance of patients.The objective of the following study was to analyse ...
Vainshelboim Baruch B Pulmonary Institute (Messrs Vainshelboim and Fox, Ms Yehoshua, and Drs Fuks, Schneer, and Kramer), Department of Cardiothoracic Surgery (Dr Saute), and Echocardiography Unit, Department of Cardiology (Dr Sagie), Rabin Medical Center, Beilinson Hospital, Petach Tikva, Israel; and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel (Drs Sagie and - - 2014
Pneumonectomy results in impairments of pulmonary function and exercise intolerance associated with respiratory limitations. However, exercise capacity and functional capacity are less known at long-term followup. The aims of this study were to assess exercise tolerance and functional capacity among long-term postpneumonectomy patients and to identify the limiting factors in ...
Vainshelboim Baruch B Pulmonary Institute, Rabin Medical Center, Beilinson Hospital, Petach Tikva, - - 2014
Background: Idiopathic pulmonary fibrosis (IPF) is a chronic, devastating, interstitial lung disease, with few therapeutic options. IPF is characterized by pulmonary restriction, dyspnea, hypoxemia, exercise intolerance and poor quality of life (QOL). Objectives: We aimed to examine the effect of exercise training (ET) on clinical outcomes in IPF patients. Methods: ...
Casey Helen H Department of Cardiology, Musgrove Park Hospital, Taunton TA1 5DA, Somerset, - - 2014
Lesson Swimming-induced pulmonary oedema/edema (SIPO/SIPE) is likely to become commoner with increasing popularity of endurance sports meaning an increased awareness by participants, organisers and medical personnel is important, especially as individuals are at increased risk of future life threatening episodes and drowning if an accurate diagnosis and appropriate advice are ...
Andersen Mads J MJ Division of Cardiovascular Diseases, Department of Medicine, Mayo Clinic Rochester, Rochester, MN; Department of Cardiology, Aarhus University Hospital, Aarhus, - - 2014
-Invasive hemodynamic exercise testing is commonly used in the evaluation of patients with suspected heart failure with preserved ejection fraction (HFpEF) or pulmonary hypertension. Saline loading has been suggested as an alternative provocative maneuver, but the hemodynamic changes induced by the two stresses have not been compared. -Twenty-six subjects (aged ...
Nordvall Strömberg Petronella P Department of Community Medicine and Rehabilitation, Physiotherapy, Umeå University , Umeå , - - 2014
Abstract Purpose: The purpose of this study is to describe thoughts and attitudes of patients with chronic obstructive pulmonary disease (COPD) when talking about exercise training as treatment. Methods: Semi-structured interviews were performed and analyzed with the grounded theory method. Four men and six women were interviewed (ages 66-84 years), ...
Jolley Caroline J CJ King's College London Division of Asthma, Allergy and Lung Biology, King's College London School of Medicine, King's Health Partners, London, UK - - 2014
The aim of this study was to test the hypothesis that neural respiratory drive, measured using diaphragm electromyogram (EMGdi) activity expressed as a percentage of maximum (EMGdi%max), is closely related to breathlessness in chronic obstructive pulmonary disease. We also investigated whether neuroventilatory uncoupling contributes significantly to breathlessness intensity over an ...
Leung Nelson N Division of Nephrology and Hypertension; Division of - - 2014
A 74-year-old white male, lifetime non-smoker underwent evaluation for a three year history of dyspnea. Patient was a former professional athlete who was still working full time. He had remained physically fit and was able to perform his regular exercise routine which included 25 minutes on the elliptical machine plus ...
Dowman Leona L Department of Physiotherapy, La Trobe University, Melbourne, Australia, - - 2014
Interstitial lung disease (ILD) is characterised by reduced functional capacity, dyspnoea and exercise-induced hypoxia. Pulmonary rehabilitation, an intervention that includes exercise training, is beneficial for people with other chronic lung conditions; however its effects in ILD have not been well characterised. • To determine whether pulmonary rehabilitation in patients with ...
Tanaka Takako T Department of Cardiopulmonary Rehabilitation Science, Nagasaki University Graduate School of Biomedical Sciences, - - 2014
[Purpose] To examine the long-term effects of air pollution on the physical functioning of a group of officially acknowledged victims of pollution-related illnesses (Victims group) who were exposed to air pollution more than 50 years ago, we compared them with age-matched patients with chronic obstructive pulmonary disease (COPD group). [Subjects and ...
Seo KyoChul K Department of Physical Therapy, Korea Nazarene University, Republic of - - 2014
[Purpose] The purpose of this study was to determine whether proprioceptive neuromuscular facilitation (PNF) respiration exercise increases the pulmonary function of normal adults. [Subjects and Methods] Twenty-eight normal adults in their 20s were randomly assigned to an experimental group (n=14) or control group (n=14). Over the course of four weeks, ...
Pradella Cristiane O CO Pulmonary Rehabilitation Center, - - 2014
The aim of this study was to develop an efficient, low-cost, home-based pulmonary rehabilitation program and to evaluate the impact of the program on exercise as measured by the 6-min walk test (6MWT) and treadmill endurance test. Twenty-nine subjects with COPD (FEV1 = 62.4 ± 10.7% of predicted, 62.4 ± ...
Vernillo G G Department of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy; CeRiSM, Research Center "Sport, Mountain and Health", University of Verona, Rovereto, - - 2014
This study aimed to assess the effects of an extreme mountain ultramarathon (MUM, 330 km, 24 000 D+) on lung function. Twenty-nine experienced male ultramarathon runners performed longitudinally [before (pre), during (mid), and immediately after (post) a MUM] a battery of pulmonary function tests. The tests included measurements of forced vital capacity, ...
Hassel Erlend - - 2014
BackgroundRight ventricular dysfunction in COPD is common, even in the absence of pulmonary hypertension. The aim of the present study was to examine the effects of high intensity interval training (HIIT) on right ventricular (RV) function, as well as pulmonary blood vessel remodeling in a mouse model of COPD.Methods42 female ...
Wibmer Thomas T Department of Internal Medicine II, University Hospital of Ulm, Ulm, Germany. - - 2014
There is growing evidence that exercise-induced variation in lung volumes is an important source of ventilatory limitation and is linked to exercise intolerance in COPD. The aim of this study was to compare the correlations of walk distance and lung volumes measured before and after a 6-min walk test (6MWT) ...
Neder J Alberto JA 1Respiratory Investigation Unit, Queen's University & Kingston General Hospital , Kingston, Ontario , - - 2014
Abstract The difference between total lung capacity (TLC) by body plethysmography and alveolar volume (VA) from the single-breath lung diffusing capacity measurement provides an index of ventilation distribution inequalities in COPD. The relevance of these abnormalities to dyspnea and exercise intolerance across the continuum of disease severity remains unknown. Two-hundred ...
Fuschillo Salvatore S Pulmonary Rehabilitation Unit - - 2014
Patients with kyphoscoliosis and severe respiratory impairment frequently experience reduction in exercise tolerance, limitation in daily life activities, and deterioration in health-related quality of life (HRQOL). Noninvasive ventilation (NIV) as an add-on treatment to long-term oxygen therapy (LTOT) was shown to improve symptoms and HRQOL in these patients. Pulmonary rehabilitation ...
van Gestel Arnoldus J R AJ Department of Pulmonary Medicine, Cantonal Hospital, St. Gallen, - - 2014
Background: The 6-min walk test (6MWT) is representative of daily life activities and reflects the functional capacity of patients with chronic obstructive pulmonary disease (COPD). Information on the cardiopulmonary and gas exchange responses to the 6MWT is limited. Objectives: We aimed to analyze the breath-by-breath cardiopulmonary and gas exchange responses ...
López-García A A Department of Physiotherapy, Faculty of Physiotherapy, University of A Coruña (UDC), Spain - - - 2014
Muscular training is the corner stone of pulmonary rehabilitation programs. To evaluate the effects of a muscular training program -- carried out on COPD subjects with antecedents of moderate or severe exacerbation -- on exercise tolerance, Health Related Quality of Life (HRQoL) and illness prognosis. A quasi--experimental study. University Hospital ...
O'Donnell Denis E DE Queen's University and Kingston General Hospital, Kingston, Ontario, Canada;1Queen's University and Kingston General Hospital, Kingston, Ontario, Canada. - - 2014
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide and, although it is a preventable and treatable disease, it often remains undiagnosed in patients with mild disease. It is now evident that pathologic changes and physiologic impairment start early in disease progression, and even patients ...
Yeh Gloria Y - - 2014
Chronic obstructive pulmonary disease (COPD) is a chronic, progressively debilitating condition that is prevalent in the US and worldwide. Patients suffer from progressive dyspnea and exercise intolerance. Physical exercise is beneficial, but conventional pulmonary rehabilitation programs are underutilized. There remains a need for novel interventions that improve symptoms, quality-of-life, and ...
Guenette Jordan A JA Respiratory Investigation Unit, Queen's University and Kingston General Hospital, Kingston, ON, Canada Dept of Physical Therapy, University of British Columbia, Vancouver, BC, Canada Centre for Heart Lung Innovation, Providence Health Care Research Institute, University of British Columbia, St. Paul's Hospital, Vancouver, BC, - - 2014
The purpose of this study was to determine if a dissociation existed between respiratory drive, as estimated by diaphragmatic electromyography (EMGdi), and its pressure-generating capacity during exercise in mild chronic obstructive pulmonary disease (COPD) and whether this, if present, had negative sensory consequences. Subjects meeting spirometric criteria for mild COPD ...
Ho Jen-Yu JY a Department of Athletic Performance , National Taiwan Normal University , Taipei , - - 2014
This study examined hormonal responses to low-intensity resistance exercise under mild simulated hypoxia. Ten resistance untrained men performed five sets of 15 repetitions of squat exercise at 30% of 1RM under normobaric hypoxia (FiO2 = 15%) and normoxia in a cross-over and counter-balanced design. Blood lactate (LAC), growth hormone (GH), ...
Eliakim A A 1Child Health & Sports Center, Pediatric Department, Meir Medical Center, Sackler School of Medicine, Tel-Aviv University, Israel. 2The Zinman College of Physical Education and Sport Sciences, Wingate Institute, Netanya, - - 2014
Exercise-associated effects on the GH→IGF-I axis were studied, mainly following aerobic exercise. We determined the gender effect on the GH→IGF-I axis response to a standard all-out Wingate anaerobic test (WAnT) in healthy active young adult males and females (males=12, females=16, age range: 24-34 years). Blood samples for GH and IGF-I, ...
JanukonytÄ— J J Department of Endocrinology and Internal Medicine, Aarhus University Hospital, Aarhus, Denmark. Electronic address: - - 2014
Diurnal variation in serum growth hormone (s-GH) levels after exogenous GH delivery has previously been reported in patients with no endogenous GH secretion. Changes in postural position or physical activity, leading to changes in blood flow and/or lymphatic drainage may be underlying explanations. The primary aim of this study is ...
Moeller Chad R CR Arizona Diamondbacks Baseball Club, - - 2014
Context :  Alterations in scapular muscle activation, which are common with glenohumeral (GH) injuries, affect stability and function. Rehabilitation aims to reestablish activation between muscles for stability by progressing to whole-body movements. Objective :  To determine scapular muscle-activation ratios and individual muscle activity (upper trapezius [UT], middle trapezius [MT], lower ...
Voss Sven Christian SC Anti-Doping Lab Qatar, PO Box 27775, Doha, Aspire Zone, Doha, - - 2014
The major objective of this study was to investigate the effects of several days of intense exercise on the growth hormone marker approach to detect doping with human growth hormone (hGH). In addition we investigated the effect of changes in plasma volume on the test. Fifteen male athletes performed a ...
Andrews Leanne L School of Health and Human Sciences, University of Essex, Wivenhoe Park, Colchester CO4 3SQ, UK. Electronic address: - - 2014
To investigate changes and differences in patient outcomes over time for 6, 7 and 8 week pulmonary rehabilitation programmes in order to identify optimal duration. Community based pulmonary rehabilitation programmes in the East of England. In total 363 participants completed one of the three pulmonary rehabilitation programmes. Patients with a ...
Budnar Ronald G RG Jr 1Applied Physiology Laboratory Department of Kinesiology, Health Promotion and Recreation University of North Texas Denton, TX 76203 2Department of Biological Sciences University of North Texas Denton, TX - - 2014
The purpose of this investigation was to examine the acute hormonal response to the kettlebell swing exercise. Ten recreationally resistance trained men (24±4 y, 175±6 cm, 78.7±9.9 kg) performed 12 rounds of 30 seconds of 16 kg kettlebell swings alternated with 30 seconds of rest. Blood samples were collected before ...
Rezaee S S Department of Physiotherapy Tarbiat Modares University, Tehran, Iran - - - 2014
Aim: This study investigated the influence of resistance (R) following endurance (E) exercise or ER on acute hormonal responses, such as growth hormone (GH), total testosterone (TT), free testosterone (FT), IGF-1, and cortisol. Methods: Ten healthy young men with an average age of 23.9 years (±0.7 y), a height of ...
Ackerman James - - 2014
Antioxidant supplementation is known to increase human endogenous antioxidant (AOX) capacity providing a means of blunting exercise induced reactive oxygen species (ROS). The purpose of this study was to compare the effects of a single acute dose of an AOX (vs blinded placebo) on muscle contractile performance and hormonal responses ...
Nindl Bradley C BC 1Military Performance and 2Military Nutrition Divisions, U.S. Army Research Institute of Environmental Medicine, Natick, - - 2014
The pulsatile secretion pattern of growth hormone (GH) is an important parameter of GH action at peripheral tissues and more information is needed on how exercise impacts GH secretion. This study hypothesized that both aerobic and resistance exercise would exhibit dose-response relationships with respect to exercise duration and 20-h post-exercise ...
da Silva Davi Vieira Teixeira DV Chemistry Institute, Federal University of Rio de Janeiro, Rio de Janeiro, - - 2014
Nutritional supplements based on the amino acid L-arginine have been hypothesized to improve exercise performance by increasing levels of insulin and growth hormone (GH). Changes of these parameters in response to L-arginine supplementation may clarify the mechanisms underlying its putative physiological effects on physical performance. The aim of the study ...
Galy Olivier O Laboratory ACTES, (EA 3596: Department of Physiology), Faculty of Physical Activity and Sports, University of Guadeloupe, Pointe à Pitre, France; Laboratory CNEP (EA 4242), University of New Caledonia, Nouméa, New - - 2014
Growth hormone (GH) may stimulate water loss during exercise by activating sweating. This study investigated GH secretion and water loss during sequential cycling and running, taking postural changes into account. The two exercise segments had similar durations and were performed at the same relative intensity to determine their respective contributions ...
El Kafy Ehab Mohamed Abd EM Department of Physical Therapy for Disturbances of Growth and Developmental Disorders in Children and Its Surgery (Dr Kafy), Faculty of Physical Therapy, Cairo University, Cairo, Egypt; Physical Therapy Department (Drs Kafy and Helal), Faculty of Applied Medical Sciences, Umm Al Qura University, Makkah, Saudi - - 2014
To examine effects of a rowing exercise regimen versus a chest physical therapy program on pulmonary function in children with Down syndrome. Twenty-nine participants of both sexes, between 8 to 12 years of age, participated in this study. They were assigned randomly into 2 study groups. The first group (A) ...
Osterling Kristin K School of Physiotherapy, Dalhousie University, Halifax, NS, - - 2014
The objective of this systematic review was to determine whether people with moderate to severe COPD who are participating in pulmonary rehabilitation and exercising at high intensity demonstrate the changes in ventilatory parameters that are associated with decreased dyspnea. The authors searched EMBASE, The Cochrane Library, and CINAHL databases up ...
Larson Janet L JL Division of Acute, Critical and Long-Term Care Programs, School of Nursing, University of Michigan, Ann Arbor, MI, USA ; Department of Biobehavioral Health Science, College of Nursing, University of Illinois at Chicago, Chicago, IL, - - 2014
People with chronic obstructive pulmonary disease lead sedentary lives and could benefit from increasing their physical activity. The purpose of this study was to determine if an exercise-specific self-efficacy enhancing intervention could increase physical activity and functional performance when delivered in the context of 4 months of upper body resistance ...
Keusch Stephan S Clinic of Pulmonology, University Hospital of Zurich, 8091 Zurich, - - 2014
Data on exercise pulmonary hemodynamics in healthy people and patients with pulmonary hypertension (PH) are rare. We analyzed exercise right heart catheterization (RHC) data in a symptomatic collective referred with suspected PH to characterize the differential response by diagnostic groups, to correlate resting with exercise hemodynamics, and to evaluate safety. ...
Nardini Stefano S Pulmonary and TB Unit, Vittorio Veneto General Hospital, Vittorio Veneto, TV - - 2014
The most recent guidelines define COPD in a multidimensional way, nevertheless the diagnosis is still linked to the limitation of airflow, usually measured by the reduction in the FEV1/FVC ratio below 70%. However, the severity of obstruction is not directly correlated to symptoms or to invalidity determined by COPD. Thus, ...
Ijiri Naoki N Department of Respiratory Medicine, Graduate School of Medicine, Osaka City University, Osaka, - - 2014
New parameters in the 6-minute walk test (6MWT) are required for comprehensive analysis of exercise capacity in patients with chronic obstructive pulmonary disease (COPD). The aim of the present study was to apply a novel index, the desaturation distance ratio (DDR), to clinical research on COPD as an estimate of ...
Wu Weibing W Department of Sports Medicine, Shanghai University of Sport, Shanghai, People's Republic of - - 2014
Tai Chi is a traditional Chinese mind-body exercise that has been widely practiced in the People's Republic of China for many centuries. This exercise has also been applied as a training modality in pulmonary rehabilitation programs for stable chronic obstructive pulmonary disease (COPD). This systematic review and meta-analysis aimed to ...
Trilk Jennifer L JL Exercise is Medicine Education Committee, Assistant Professor, Department of Biomedical Sciences, University of South Carolina School of Medicine Greenville, Greenville, South Carolina, - - 2013
Educating medical students and other health professionals in training on the importance of healthy lifestyles for prevention and treatment of disease is essential to transforming healthcare. At the University of South Carolina School of Medicine Greenville (USC SOM Greenville), we are incorporating the 'Exercise is Medicine' Knowledge, Skills and Abilities ...
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