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Fell R D - - 1981
Rats were given a daily injection of L-epinephrine, 100 micrograms/100 g body wt, for 6 wk. The hearts of the epinephrine-treated animals were heavier (11.5%), and blood glucose and plasma insulin concentrations were lower than those of control rats. Acute responses to epinephrine were compared in the two groups. An ...
Hultén B - - 1981
1. The glycogen-depletion patterns were studies as a measure of muscle-fibre recruitment in patients after leg injuries (fractures, ligament injuries). Intermittent isometric and dynamic isokinetic knee extension were performed with 30 and 50% of the maximal isometric torque of the injured leg. In a third group isokinetic and dynamic exercise ...
Karlsson J - - 1981
Maximal voluntary contractions (MVC) were performed by five male subjects as repeated knee extensions separated by 13-s rest periods for the purposes of studying performance capability, physiologic responses, and recruitment patterns among fast-twitch (FT) and slow-twitch (ST) extrafusal muscle fibers for this type of exercise. Exercise was performed on an ...
Sherman W M - - 1981
This study examined the effect of three exercise-diet regimens on muscle glycogen supercompensation and subsequent performance during a 20.9-km run. A diet containing 15% carbohydrate (CHO,L), 50% CHO (M), or 70% (CHO (H) was arranged in three trials as follows: trial A = 3 days L, 3 days H; trial ...
Jacobs I - - 1981
The present study was designed to evaluate the effects of changes in glycogen concentrations on lactate accumulation in human skeletal muscle during a 1 min maximal muscle fatigue test (MFT). All subjects first performed the MFT during a control experiment. Four subjects then performed the MFT again 1 h after ...
Eriksson B O - - 1981
Muscle biopsies were taken from the quadriceps muscle during rest and exercise in 16 young men (ages 16-28 years) operated upon for coarctation of the aorta during childhood and 10 healthy men (ages 19-25 years). Resting values and depletion after exercise for ATP, CP and glycogen were similar in the ...
Sharman I M - - 1981
Carbohydrate loading enables an athlete to build up stores of muscle glycogen. Such raised levels increase work times and are therefore of real benefit to long-distance runners. It is unclear how frequently the regimen can be repeated with the same advantageous results. There are possible disadvantages in the regimen, and ...
Palmer W K - - 1981
Numerous cellular biochemical events caused by hormones are mediated through cyclic AMP. Although many changes occur in the cell during exercise that could be attributed to this nucleotide, little evidence is available implicating it as an important regulator of exercise metabolism. In this investigation it was found that a 60 ...
Conlee R K - - 1981
Glycogen supercompensation is the term used to denote the abnormally high levels of glycogen found in the heart shortly after an exercise-induced reduction of the substrate. Using rats, we tested whether this condition was linked to the use of plasma free fatty acids (FFA), which normally rise with exercise. Before ...
Terblanche S E - - 1981
Rats were fed either 1 g of glycerol or 1 g of glucose following exercise to exhaustion. Glucose feeding resulted in a rapid increase in blood glucose, with attainment of peak hyperglycemia within 1 h and of peak muscle glycogen in about 2 h. Feeding 1 g of glycerol resulted ...
Teramoto T - - 1981
Biopsies of the external and sphincter taken from 24 male patients with haemorrhoids were subjected to examination using histochemical techniques. Fibre size (type 1 mean: 33 micrometers +/- 11.0 SD and type 2 mean: 47.9 micrometers +/- 15.0 SD) was increased when compared with control subjects. The distribution of muscle ...
Phinney S D - - 1980
To study the capacity for moderate endurance exercise and change in metabolic fuel utilization during adaptation to a ketogenic diet, six moderately obese, untrained subjects were fed a eucaloric, balanced diet (base line) for 2 wk, followed by 6 wk of a protein-supplemented fast (PSF), which provided 1.2 g of ...
Poland J L - - 1980
Carbohydrate and lipid substrates were measured in rats during recovery following exercise or a 24-h fast and compared with values from time-matched control (rested, fed) rats. After exercise muscle glycogen recovered at the expense of liver glycogen repletion. Myocardial glycogen supercompensated whereas soleus, red vastus lateralis (RVL) and white vastus ...
Gaesser G A - - 1980
Patterns of postexercise glycogen repletion in heart, skeletal muscle, and liver in the absence of exogenously supplied substrates during the first 4 h of recovery were assessed. Female Wistar rats were run to exhaustion using continuous (1.0 mph, 15% grade) and intermittent (alternate 1-min intervals at 0.5 and 1.5 mph, ...
Estler C J - - 1980
The effect of naftidrofuryl (40 micrograms/g i.p.) on the ATP, phosphocreatine (PC), glycogen, lactate and pyruvate contents of the heart during respiratory arrest and postanoxic recovery was studied in mice. Naftidrofuryl increased he PC-content of the heart of normal mice. It did not prevent the metabolic changes brought about by ...
Fell R D - - 1980
Despite carbohydrate starvation (fasting or fat feeding) considerable glycogen accumulation, ranging from 20 to 30 mumol glucose/g, occurred in hindlimb muscles of rats following exhausting exercise that caused severe muscle and liver glycogen depletion and hypoglycemia. The largest increase in muscle glycogen occurred during the first 3 h after exercise ...
Lemon P W - - 1980
Serum urea increases with exercise duration suggest prolonged exercise may be analogous to starvation where protein catabolism is known to occur. The purpose of this investigation was to alter muscle glycogen levels and to study the effect on protein catabolism. Six subjects (27-30 yr) pedaled a cycle ergometer for 1 ...
Koeslag J H - - 1980
Post-exercise ketosis has been shown to occur in untrained subjects after 3--4 hours' walking, 1 1/2 hours' running or faster 20 minutes' cycling. Trained athletes appear to be resistant to post-exercise ketosis. The present study was undertaken to investigate whether post-exercise ketosis was related to the utilization of muscle glycogen ...
Dhalla N S - - 1980
Isolated rat hearts were perfused with aerobic substrate-free medium for different intervals during which changes in functional and metabolic events were examined. The contractile force was maintained for 30 min but thereafter declined toward zero over a period of 90 min. Before the onset of contractile failure, glycogen decreased by ...
Rahkila P - - 1980
Seven physically fit (well-trained, maximal oxygen uptake 69.6 +/- 4.4 ml x kg-1 min-1) and eight less fit (moderately trained, maximal oxygen uptake 56.1 +/- 5.7 ml x kg-1 x min-1) healthy male subjects were exercised for 4 h by bicycle ergometry against a pedalling resistance calculated to cause oxygen ...
Brzezińska Z - - 1979
Muscle biopsies for glycogen determinations were taken from dogs before (controls) and after prolonged treatment with thyroid hormones (T4 or T3). The glycogen content in quadriceps femoris was measured before exercise, immediately after its cessation, and during 24h of post-exercise recovery. The effect of thyroxine treatment on the liver glycogen ...
Winder W W - - 1979
Liver glycogenolysis may be controlled by glucagon or catecholamine-induced changes in cAMP or by cAMP-independent mechanisms. The purpose of these experiments was to determine whether an increase in liver cAMP occurs during exercise at a time when the rate of liver glycogenolysis is greatly accelerated. Rats were taught to run ...
Segal S S - - 1979
To study a possible relationship between blood lactate and O2 consumption (VO2) after exercise, 11 male subjects exercised on a bicycle ergometer at moderate and heavy work loads in both normal glycogen and glycogen-depleted states. At rest, glycogen depletion resulted in significantly lowered blood glucose and lactate concentrations, CO2 production ...
Clark J H - - 1979
The purpose of this study was to determine the influence of diurnal variations of muscle and liver glycogen stores on exercise endurance in male albino rats. Animals were swum to exhaustion at either 0700 or 1900 h, after which samples of soleus, white vastus lateralis, and red vastus lateralis muscles ...
Kochan R G - - 1979
We investigated the role of glycogen synthase in supranormal resynthesis (supercompensation) of skeletal muscle glycogen after exhaustive exercise. Six healthy men exercised 60 min by cycling with one leg at 75% VO2max, recovered 3 days on a low-carbohydrate diet, exercised again, and recovered 4 days on high-carbohydrate diet. Glycogen and ...
Taylor A W - - 1979
The effects of running or swimming regimens of 4 months duration, coupled with three different feeding patterns were investigated on the following parameters: (1) fat cell diameter, number, lipid content and free fatty acid mobilization; (2) skeletal muscle and liver glycogen storage and utilization; (3) work capacity. Regular enforced rigorous ...
Segerbo B E - - 1979
High pressure oxygen (HBO) and 1,1-dimethylhydrazine (UDMH) both cause grand mal seizures, brain glycogen degradation, and inhibition of glutamic acid decarboxylase (GAD). Brain glycogen degradation is a sudden process that is perhaps initiated by convulsions in the case of UDMH-poisoning, but a gradual decrease in glycogen is detectable before the ...
Pohoska E - - 1979
2-months restriction of physical activity of dogs markedly reduced their capacity for prolonged running. The rate of exercise-induced Tre increases was significantly higher in the cage-confined dogs in comparison with controls. At the point of exhaustion blood glucose concentration and muscle glycogen content were similar in the control and cage-confined ...
Brzezińska Z - - 1979
Post-exercise changes in muscle glycogen content and blood metabolites in the dogs treated with triiodothyronine. Acta Physiol. Pol., 1979, 30 (2) : 241--252. Prolonged T3-treatment markedly affected muscle glycogen content which was significantly lower than in controls both under resting conditions and after prolonged exercise. The post-exercise rate of the ...
Thomson J A - - 1979
Muscle glycogen depletion in ST, FTa and FTb fibres were studied in human subjects undergoing two distinctly different modes of bicycle exercise. Two hours of submaximal exercise (60% of VO2 max) produced a 77% decline in muscle glycogen concentration accompanied by only minor elevations in muscle and blood lactate levels ...
Ahmad M - - 1979
This study shows that significant changes in the pattern of glycogen deposition are brought about by irradiation with 2,000 R gamma-rays. The sharp fall during the 1st week can be attributed to its emergent mobilization. However, glycogen stored in the liver during the 2nd and 3rd week prior to the ...
Yashiro M - - 1979
The effects of voluntary exercise on the growth, glycogen of muscle and lipid contents of the liver and serum of mice fed different levels of dietary protein were investigated. In both the exercise and non-exercise groups, body weight gains were significantly greater in the 20% and 30% protein diet groups ...
Frenkl R - - 1979
In Experiment 1 a double-phase test diet (high-protein low-carbohydrate phase (HP): 5 days, high-carbohydrate phase (HC): 2 days) was compared to a normal diet by measuring all-out performance in rats trained by steady or interval swimming exercise. The tests carried out on the 8th day showed the swimming performance to ...
Stankiewicz-Choroszucha B - - 1978
Intramuscular triglycerides mobilization during prolonged physical exercise was examined in rats fed ad libitum, in rats fasted for 24 h and in rats treated with nicotinic acid. It has been found that during exercise the intramuscular triglyceride level was markedly reduced only in the red muscle but not in the ...
Björntorp P - - 1978
Recent information indicates that the capacity of man to store carbohydrate energy by transformation into fatty acids synthetized de novo is very limited in adipose tissue as well as in liver and intestine. This seems to be in contrast to other species such as the rat where de novo fatty ...
Górski J - - 1978
Effect of prolonged exercise, acute cold exposure, and 24-h fasting on the glycogen level in the uterus of rats spayed and than treated with peanut oil or estradiol was investigated. It has been found that exercise increases significantly though transitorily the glycogen level in the uterus of the oil-treated group. ...
Bławacka M - - 1978
Glycogen resynthesis was studied in muscles and liver of Wistar rats after a single bout of physical exercise, which included 30 min of enforced swimming in water at 32 degrees C. The experiment was carried out on untrained rats which rested after the exercise from 30 min to 24 h, ...
Maehlum S - - 1978
The influence of 12 h of fasting after prolonged severe exercise on the muscle glycogen concentration was studed in 5 normal subjects. The subjects exercised in the post absorptive state at 70% of max. Vo2 till exhaustion, then rested for 12 h. No food was allowed during recovery. Blood samples ...
Maehlum S - - 1978
Glucose (100 g) was ingested 15 min after bicycle exercise until exhaustion at a work load corresponding to 70% of maximal uptake (series 1), 14--15 h after an identical exercise period, no food being taken in the interval (series 2), and by nonexercised control subjects. Splanchnic glucose output in the ...
Lowenstein J M - - 1978
The following evidence demonstrates that ammonia production in muscle occurs via the reactions of the purine nucleotide cycle: i) Extracts of cytosol which lack glutamine dehydrogenase produce ammonia under conditions that mimic muscle doing work. In such extracts a member of the purine nucleotide cycle (AMP, IMP, or adenylosuccinate) must ...
Galbo H - - 1978
The importance of the sympatho-adrenal system for the pancreatic hormonal response to exercise and, furthermore, the role of glucagon and catecholamines for the hepatic glycogen depletion during exercise were studied. Rats were either surgically adrenomedullectomized and chemically sympathectomized with 6-hydroxydopamine or shamtreated. Two weeks later the rats had either rabbit-antiglucagon ...
Peute J - - 1978
The female zebrafish is capable of producing mature eggs on the fifth day of each reproductive cycle. During this five-day period the ultrastructure of hepatocytes undergoes several changes. The number of nuclear pores increases rapidly during spawning, followed by a proliferation of RER within 24 h. Two days after spawning, ...
Green H J - - 1978
The glycogen depletion patterns in the vastus lateralis muscle were studied during ice skating using eight hockey players. For each subject, exercise consisted of either repeated bouts (10) of high intensity work (120% Vo2 max) or continuous work (60 min) of low intensity (55% Vo2 max). During continuous skating, glycogen ...
MacDougall J D - - 1977
Nine healthy subjects were studied under control conditions and following 5 mo of heavy resistance training and 5 wk of immobilization in elbow casts. Needle biopsies were taken from triceps brachii and analyzed for adenosine triphosphate (ATP), adenosine diphosphate (ADP), creatine (C), creatine phosphate (CP, and glycogen concentrations. Training resulted ...
Costill D L - - 1977
Seven men were studied during 30 min of treadmill exercise (approximately 70% VO2 max) to determine the effects of increased availability of plasma free fatty acids (FFA) and elevated plasma insulin on the utilization of muscle glycogen. This elevation of plasma FFA (1.01 mmol/1) with heparin (2,000 units) decreased the ...
Blawacka M - - 1977
The effect of exercise of glycogen level in skeletal muscles and liver was studied in Wistar rats. The previously untrained animals were subjected to one-time exercise in form of swimming in water at 32 degrees C for 10, 20 and 30 min. The glycogen level in the muscles (in g ...
Goodman M N - - 1977
Ammonia production by hind limbs of rat was studied in perfused preparations during rest, exercise, and hypoxia, and while the perfusate contained epinephrine or cyanide. Ammonia production by hind limbs was also studied in situ during rest and exercise. Strong correlations were observed between ammonia, IMP, and lactate formation. Adenylosuccinate ...
McClellan M A - - 1977
Experiments were performed to measure the stability of opsonins during storage of whole blood collected in CPD solution and stored at 4 C. Three units were collected, and aliquots removed and recalcified on days 0, 3, 7, 14, 21, and 28. Reconstituted serum was immediately frozen and stored at -70 ...
MacDougall J D - - 1977
Six subjects exercised to exhaustion on a cycle ergometer at intensities corresponding to approximately 140% of their maximal aerobic power. Subjects attempted to pedal for 1-min intervals with 3-min rest periods between, and continued until 30 s of exercise could no longer be maintained. Venous blood was sampled for lactate ...
Conlee R K - - 1977
Previous studies have shown that cardiac glycogen content is replenished to supranormal levels after exercise. To better understand this phenomenon glycogen synthase (GS) %I activity as well as glucose 6-phosphate (G-6-P) and glycogen (G) concentrations were measured in hearts from normal and alloxan diabetic rats killed at various time intervals ...
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