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Results 201 - 250 of 911
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Chapman D W - - 2008
OBJECTIVES: Large inter-subject variability in responses to eccentric exercise has been reported. This study investigated the hypothesis that the variability of changes in indirect markers of exercise-induced muscle damage (EIMD) would be explained by work performed and/or torque generated during eccentric exercise. METHODS: Subjects (n = 53) performed 60 maximal ...
Bailey D M - - 2007
The aim of this study was to assess the effects of cold-water immersion (cryotherapy) on indices of muscle damage following a bout of prolonged intermittent exercise. Twenty males (mean age 22.3 years, s = 3.3; height 1.80 m, s = 0.05; body mass 83.7 kg, s = 11.9) completed a ...
Pettersson Jonas J AstraZeneca R&D Lund, Lund, - - 2008
The occurrence of idiosyncratic drug hepatotoxicity is a major problem in all phases of clinical drug development and the leading cause of postmarketing warnings and withdrawals. Physical exercise can result in transient elevations of liver function tests. There is no consensus in the literature on which forms of exercise may ...
Kubota Jun - - 2007
This study was designed to determine the regional differences of magnetic resonance (MR) measurements in the hamstrings [biceps femoris muscle long head (BFl) and short head (BFs), semimembranosus muscle (SM), and semitendinosus muscle (ST)] following eccentric knee-flexion exercise. Twelve male volunteers performed eccentric knee-flexion exercise. Maximum isometric torque, plasma creatine ...
Rice T L - - 2008
OBJECTIVE: Inflammatory mediators, such as tumour necrosis factor alpha (TNFalpha), may contribute to delayed-onset muscle soreness. The effect of neutralising TNFalpha with etanercept, a soluble TNFalpha receptor, on delayed-onset muscle soreness (DOMS) induced in the quadriceps muscle was analysed. DESIGN: On two separate occasions at least 6 weeks apart, etanercept ...
Lavender Andrew P - - 2008
This study investigated the hypothesis that a light eccentric exercise (ECC) that does not induce a loss of muscle function and delayed onset muscle soreness would confer a protective effect against a more strenuous ECC. Eighteen young men were randomly placed into two groups: 10-40% (n=9) and 40% (n=9). Subjects ...
Klossner Stephan - - 2007
The muscle has a wide range of possibilities to adapt its phenotype. Repetitive submaximal concentric exercise (i.e., shortening contractions) mainly leads to adaptations of muscle oxidative metabolism and endurance while eccentric exercise (i.e., lengthening contractions) results in muscle growth and gain of muscle strength. Modified gene expression is believed to ...
Givoni Nathan J - - 2007
This is a report of the effects of exercise on position matching at the knee. Young adult subjects were required to step down a set of stairs (792 steps), representing eccentric-biased exercise of the quadriceps muscle, or step up them, concentric-biased exercise. Immediately after eccentric exercise subjects showed a mean ...
Nedergaard A - - 2007
Unaccustomed exercise is known to produce strength loss, soreness, and myocellular disruption. With repeated application of exercise stimuli, the appearance of these indexes of muscle damage is attenuated, the so-called "repeated bout effect." No direct connection has been established between this repeated bout effect and exercise-induced increases in protein turnover, ...
Beck Travis W - - 2007
This investigation examined the effects of a protease supplement on selected markers of muscle damage and delayed-onset muscle soreness (DOMS). The study used a double-blinded, placebo-controlled, crossover design. Twenty men (mean +/- SD age = 21.0 +/- 3.1 years) were randomly assigned to either a supplement group (SUPP) or a ...
Kirk, Gregory
Recorded on July 27, 2007 by Eugene Barsky, Physiotherapy Outreach Librarian, UBC
Jensky Nicole E NE Division of Biokinesiology and Physical Therapy, Clinical Exercise Research Center, University of Southern California, 1540 E. Alcazar St. CHP-155, Los Angeles, CA, 90033 - - 2007
To evaluate change in myostatin, follistatin, MyoD and SGT mRNA gene expression using eccentric exercise to study mechanisms of skeletal muscle hypertrophy. Young (28+/-5 years) and older (68+/-6 years) men participated in a bout of maximal single-leg eccentric knee extension on an isokinetic dynamometer at 60 degrees /s: six sets, ...
Costa Andreas - - 2007
Evidence indicates that repeated-bouts of eccentric exercise (EE) do not exacerbate the extent of muscle damage indices, as compared to a single-bout. We hypothesized that molecular adaptations, under repeated-bouts of EE, would include suppression of muscle repair inhibitory factors such as myostatin and up-regulation of muscle repair positive regulatory factors ...
Yeung S S - - 2008
This study aims to investigate the changes in the mechanical properties of quadriceps muscle following a sub-maximal concentric-eccentric stepping exercise protocol. Twenty-four untrained healthy subjects aged 21.9 +/- 0.55 years were asked to perform a 10-minute stepping exercise where the dominant leg worked eccentrically and the non-dominant leg worked concentrically ...
Fahie-Wilson Michael N - - 2007
BACKGROUND: Macro creatine kinase type 1 (MCK1) may be the cause of elevated total serum CK activity, which can lead to diagnostic confusion. There is evidence that this problem is poorly recognized perhaps due to a lack of information on its prevalence. Precipitation with polyethylene glycol (PEG) has been described ...
Wasielewski Noah J - - 2007
To critically review evidence for the effectiveness of eccentric exercise to treat lower extremity tendinoses. Databases used to locate randomized controlled trials (RCTs) included PubMed (1980-2006), CINAHL (1982-2006), Web of Science (1995-2006), SPORT Discus (1980-2006), Physiotherapy Evidence Database (PEDro), and the Cochrane Collaboration Database. Key words included tendon, tendonitis, tendinosis, ...
Semmler John G - - 2007
The purpose of this study was to determine the effect of eccentric exercise on the ability to exert steady submaximal forces with muscles that cross the elbow joint. Eight subjects performed two tasks requiring isometric contraction of the right elbow flexors: a maximum voluntary contraction (MVC) and a constant-force task ...
Crameri R M - - 2007
Disruption to proteins within the myofibre after a single bout of unaccustomed eccentric exercise is hypothesized to induce delayed onset of muscle soreness and to be associated with an activation of satellite cells. This has been shown in animal models using electrical stimulation but not in humans using voluntary exercise. ...
Murphy Robyn M - - 2007
The function and normal regulation of calpain-3, a muscle-specific Ca(2+)-dependent protease, is uncertain, although its absence leads to limb-girdle muscular dystrophy type 2A. This study examined the effect of eccentric exercise on calpain-3 autolytic activation, because such exercise is known to damage sarcomeric structures and to trigger adaptive changes that ...
McKenzie Erica C - - 2007
OBJECTIVE: To determine the impact of successive days of endurance exercise on select serum chemistry values in conditioned Alaskan sled dogs. DESIGN: Prospective cohort study. ANIMALS: 10 conditioned Alaskan sled dogs. PROCEDURES: All dogs ran 160 km/d for 5 consecutive days. Serum was obtained prior to exercise and immediately after ...
Chung Yuen-Li YL King's College London School of Medicine, and the MRC Clinical Science Centre, Hammersmith Hospital, Imperial College School of Medicine, London, UK. - - 2007
To test the hypothesis that oral creatine supplements with exercise are more effective than exercise alone in improving muscle function in patients with established dermatomyositis or polymyositis receiving chronic medical therapies who are clinically weak yet stable. In a 6-month, 2-center, double-blind, randomized controlled trial, patients were randomized to receive ...
Hotta Norio - - 2007
We examined the effect of the amount of eccentric exercise (ECC) on ventilatory response at the onset of exercise. The first 10 s of ventilatory response to exercise while using the leg that had performed a relatively greater number of ECC repetitions was greater than that of the leg that ...
Heled Yuval - - 2007
Exertional rhabdomyolysis (ERB) is a syndrome of severe skeletal muscle breakdown. Blood levels of creatine kinase (CK) are widely used as a marker to reflect muscle breakdown. Some individuals exhibit extreme increases in blood CK after exercise and have been characterized as high responders (HR), but no clinical definition of ...
Hoang Phu D - - 2007
INTRODUCTION: In this study, we used a newly developed method for measuring passive length-tension relations of a single human muscle in vivo to quantify changes in the mechanical properties of the human gastrocnemius after eccentric exercise. METHODS: Twelve subjects performed eccentric exercise on the right leg for 1 h by ...
Schulpis Kleopatra H - - 2007
OBJECTIVE: To investigate the effect of alpha-Tocopherol (alpha-T) supplementation on S100B elevated serum levels in basketball players' training. DESIGN: Blood was obtained from 10 basketball players pre-exercise (group A), post-exercise (group B) and after 30 days on alpha-T (200 mg/24 h orally) supplementation pre- (group C) and post-training (group D). ...
Roth H J - - 2007
BACKGROUND: The reasons for the appearance of cardiacspecific troponin (cTnT) after strenuous exercise are unclear. The aim of the present study was to evaluate the cardiospecificity of the 3(rd) generation cardiac cTnT assay during and after an ultra-endurance race of 216 km at extreme environmental conditions in Death Valley. STUDY ...
KawczyƄski A - - 2007
The aim of this study was to investigate changes in mechanomyographic (MMG) and the surface electromyographic (EMG) signals during and after fatiguing shoulder eccentric contractions in a group consisting of 12 males and 12 females. Exerted force, MMG, EMG, pain and rate of perceived exertion were assessed before, during and ...
Smith Lucille L - - 2007
The purpose of this study was to examine changes in serum cytokines after repeated bouts of aerobically biased eccentric exercise. Six untrained males ran down a -13.5% treadmill grade for 60 min on two occasions (RUN1 and RUN2) at a speed equal to 75% of their VO2 peak on a ...
García-López David - - 2007
PURPOSE: Changes in nuclear factor kappaB (NF-kappaB) activation induced in peripheral blood mononuclear cells (PBMC) by acute eccentric exercise and by submaximal eccentric training were investigated. METHODS: Eleven subjects carried out two bouts of eccentric exercise separated by 6 wk of training. RESULTS: Soreness, vertical jump height, and plasma creatine ...
Paschalis V - - 2007
Impaired position sense and impaired joint reaction angle of the lower limbs after muscle-damaging activities is a serious functional limitation that may lead to an increased risk of injury, particularly in older populations. The purpose of the present study was to examine whether position sense and joint reaction angle to ...
Jeon Sang-Beom - - 2007
BACKGROUND: Intracerebral microbleeds (MBs) are frequently observed in intracerebral hemorrhage (ICH) patients. Although MBs have been shown to be pathogenetically related with ICH, it is not known whether MBs are predictors of recurrent ICHs. METHODS: Among 220 acute symptomatic primary ICH patients, 112 patients who underwent gradient-echo T2*-weighted MR imaging ...
Howatson G - - 2007
We hypothesized that a bout of high or low volume eccentric exercise would protect against muscle damage following a subsequent high volume bout and that adaptation would be attributable to neural changes, independent of the initial exercise volume. Sixteen males performed either 45 (ECC45) or 10 (ECC10) maximal eccentric contractions ...
Schneider D A - - 2007
The purpose of this study was to determine if exercise-induced delayed onset muscle soreness (DOMS) would alter O2 uptake kinetics during heavy cycling in 9 untrained females. O2 uptake kinetics were characterised during 8-min of constant-load cycling performed with and without DOMS. DOMS was caused by completing 30 min of ...
Torres R - - 2007
With the aim to analyze the influence of stretching on muscle stiffness after eccentric exercise, 30 young men (18 - 32 years old), were divided into three groups: STR, undergoing a stretching program (SP) of the dominant quadriceps muscle, ECC, undergoing exhaustive eccentric exercise, and ECC/STR, undergoing eccentric exercise, followed ...
Lavender Andrew P - - 2008
It is well documented that unaccustomed eccentric exercise induces muscle damage, but the responses of middle-aged individuals to a bout of eccentric exercise have not been reported. The purpose of this study was to compare changes in indirect markers of muscle damage following eccentric exercise of the elbow flexors between ...
Duffield Rob - - 2007
To compare the effects of three types of full-body compression garments (Skins, Adidas and Under Armour) on repeat-sprint and throwing performance in cricket players. Following familiarisation, 10 male cricket players performed four randomised exercise sessions (3 garments and a control). Each session involved a 30 min repeat-sprint exercise protocol comprising ...
Gerber J Parry - - 2007
BACKGROUND: Thigh muscle atrophy is a major impairment that occurs early after reconstruction of the anterior cruciate ligament and persists for several years. Eccentric resistance training has the potential to induce considerable gains in muscle size and strength that could prove beneficial during postoperative rehabilitation. The purpose of this study ...
Dousset Erick - - 2007
INTRODUCTION/PURPOSE: Recovery of force and stretch reflex from exhaustive stretch-shortening cycle (SSC) exercise is usually bimodal, characterized as immediate exercise-induced performance reduction, with its quick recovery followed by a longer-lasting reduction in performance. A clear parallel exists between the respective changes in performance, neural activation, and metabolic or structural exercise-induced ...
Chaler Joaquim J Department of Physical Medicine and Rehabilitation, Mútua Egara, Terrassa, Spain. - - 2007
To examine the efficiency of the difference between the isokinetic eccentric to concentric strength ratios at high and low velocities (DEC) for identifying feigned maximal shoulder external rotation effort. Previous studies have indicated that the DEC is a powerful identifier of feigned maximal effort. However comparison of maximal versus feigned ...
Piitulainen Harri - - 2008
It has been shown that intensive eccentric muscle actions lead to prolonged loss of muscle force and sarcolemmal damage. This may lead to a reduction in the excitability of the sarcolemma and contribute to the functional deficit. Experiments were carried out to test sarcolemmal excitability after eccentric elbow flexor exercise ...
Lavender Andrew P - - 2007
This study compared force fluctuations during isometric contraction following eccentric exercise of the elbow flexors between young, middle-aged, and old subjects. Ten young (20 +/- 2.0 years), 12 middle-aged (48 +/- 7.3 years), and 10 old (71 +/- 4.1 years) men performed six sets of five eccentric actions of the ...
Nottle Carmel - - 2007
Few studies have examined the effects of eccentric exercise-induced muscle damage on power despite power being a key performance variable in a number of sporting events. The aim of this study was to examine changes in anaerobic power (30-second Wingate Test), isometric strength of the knee extensors and flexors, muscle ...
Kilgallon M - - 2007
To examine the effects of eccentric and concentric progressive resistance training on muscle torque-angle relationship, 30 young adults were randomly allocated into three groups of 10, control (CTL), eccentric training (ECC) and concentric training (CON). The ECC and CON groups performed seven sessions over 3 weeks of progressive resistance training ...
Visnes Håvard - - 2007
Eccentric training has become a popular treatment for patellar tendinopathy. Our purpose was to review the evolution of eccentric strength training programmes for patellar tendinopathy with a focus on the exercise prescriptions used, to help clinicians make appropriate choices and identify areas needing further research. A computerised search of the ...
Sellwood Kylie Louise - - 2007
To determine if ice-water immersion after eccentric quadriceps exercise minimises the symptoms of delayed-onset muscle soreness (DOMS). A prospective randomised double-blind controlled trial was undertaken. 40 untrained volunteers performed an eccentric loading protocol with their non-dominant leg. Participants were randomised to three 1-min immersions in either ice water (5+/-1 degrees ...
Croisier Jean-Louis - - 2007
Lateral epicondylitis represents a frequent overuse injury. In spite of many conservative treatment procedures, prolonged symptoms and relapse are frequently observed. To compare the outcome of patients performing an isokinetic eccentric training with that of age-, gender-, activity-matched patients receiving a non-strengthening classical rehabilitation. Ninety-two patients with unilateral chronic lateral ...
FARR, Trevor
The present study investigated the hypothesis that maximal voluntary contractions (MVC) peak torque, VJ, muscle tenderness, and plasma creatine activity would be significantly less for the condition that subjects were exposed to hypoxic (H) condition for 4 hours after eccentric exercise compared with the normoxic (N) condition.
Law Roberta Y W - - 2007
QUESTION: Does warm-up or cool-down (also called warm-down) reduce delayed-onset muscle soreness? DESIGN: Randomised controlled trial of factorial design with concealed allocation and intention-to-treat analysis. PARTICIPANTS: Fifty-two healthy adults (23 men and 29 women aged 17 to 40 years). INTERVENTION: Four equally-sized groups received either warm-up and cool-down, warm-up only, ...
Brughelli Matt - - 2007
The effects of eccentric exercise on muscle injury prevention and athletic performance are emerging areas of interest to researchers. Of particular interest are the adaptations that occur after a single bout, or multiple bouts of eccentric exercise. It has been established that after certain types of eccentric exercise, the optimum ...
LaStayo Paul - - 2007
BACKGROUND AND PURPOSE: Elderly individuals participate in resistance exercise to induce an anabolic response and grow muscle to help overcome functional deficits. It is thought that a muscle damage and inflammatory response to resistance exercise is a necessary prerequisite for an anabolic and muscle growth response. METHODS: This is a ...
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