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Shave R E - - 2002
Cardiac damage has recently been implicated in the aetiology of "exercise induced cardiac dysfunction". The humoral markers of cardiac damage that have been utilised to date are not sufficiently cardio-specific to investigate this hypothesis. The aim of the present study was to examine cardiac function following prolonged exercise, and investigate ...
Totsuka Manabu - - 2002
We investigated whether there is a break point of creatine kinase (CK) release after daily endurance exercise and whether CK response depends on individual physical characteristics. Fifteen healthy young men performed 90 min of bicycle exercise for 3 consecutive days. Body composition, properties of the quadriceps femoris muscle (QFM), and ...
Ng Gabriel Y F - - 2002
STUDY DESIGN: Normative descriptive study. OBJECTIVES: Exploring the isokinetic work ratios of eccentric antagonist/concentric agonist shoulder rotators in the late cocking and deceleration phases of a forehand overhead smash in badminton players. Comparing the work ratios between dominant and nondominant shoulders. BACKGROUND: The strength of shoulder muscles for badminton players ...
Prisby, Rhonda Dianne
Purpose: This investigation evaluated the effects of a high-load (50% body weight) eccentric exercise training protocol on reloading myofibrillar damage in soleus (SOL) and extensor digitorum longus (EDL) muscles in rats following 7 days (d) of hindlimb suspension unloading (HSU). Methods: 48 female Sprague-Dawley rats were randomly stratified to four ...
Toft Anders Dyhr - - 2002
To examine the plasma interleukin (IL)-6 response in elderly (E) and young (Y) humans, 10 E and 10 Y subjects completed 60 min of eccentric lower limb exercise at the same relative oxygen uptake. Plasma IL-6 was measured before, immediately after, and 5 days into recovery from exercise, as were ...
Savage Kathleen J - - 2002
Endogenous estrogen appears to attenuate muscle damage in animals; however, similar evidence in humans is not as strong. This investigation tested the hypothesis that women taking oral contraceptives, thereby having higher exogenous estrogen levels, would be more susceptible to damage or have an attenuated recovery from exercise-induced muscle damage. Muscle ...
Haddad Fadia - - 2002
Training protocols apply sequential bouts of resistance exercise (RE) to induce the cellular and molecular responses necessary to produce compensatory hypertrophy. This study was designed to 1) define the time course of selected cellular and molecular responses to a single bout of RE and 2) examine the effects of interbout ...
Yu Ji-Guo - - 2002
Lack of staining for desmin in muscles in animal models of eccentric exercise has been suggested to reflect disruption of the desmin intermediate filament network and proposed to cause disruption of the myofibrillar apparatus and deterioration of muscle fibers. In a recent study, we examined muscle biopsies from persons who ...
Michaut Anne - - 2002
PURPOSE: This study was designed to determine whether torque decrease following an acute eccentric exercise is contraction type dependent. METHODS: Ten active males performed an exercise session consisting of five sets of ten maximal eccentric muscle actions of the elbow flexors. Before and immediately after the exercise, maximal voluntary eccentric ...
Walter T - - 2002
BACKGROUND: ACE inhibitors may have a cardioprotective effect by enhancing bradykinin levels during cardiopulmonary bypass (CPB). However, ACE inhibition could lead to unwelcome effects on the kallikrein contact phase during CPB (since reduction of kallikrein activity by aprotinin has been shown to be beneficial) and may alter the hemostasis. We ...
- - 2002
(1) Creatine occurs naturally in the body. Some is derived from dietary sources, but endogenous synthesis covers individual requirements. Creatine deficiency occurs only in subjects with genetic disorders. (2) Oral creatine supplementation at supraphysiological doses seems to slightly improve the performance of some types of muscle exercise, but only those ...
Burelle Yan - - 2002
The present study was conducted to investigate the potential role of changes in the apparent K(m) for ADP and in the functional coupling of the creatine (Cr) kinase (CK) system (CK efficiency) in explaining the tighter integration of ATP supply and demand after exercise training. Mitochondrial function was assessed in ...
Nosaka Kazunori - - 2002
This study compared maximal (MAX-ECC) and submaximal (50%-ECC) eccentric exercise of the elbow flexors. Untrained male students (n = 8) performed 3 sets of 10 repetitions of MAX-ECC with one arm and 50%-ECC with the other arm, separated by 4 weeks. In MAX-ECC, the elbow joint was forcibly extended from ...
Beaton Louise J - - 2002
PURPOSE: Vitamin E supplementation may confer a protective effect against eccentrically biased exercise-induced muscle damage through stabilization of the cell membrane and possibly via inhibition of free radical formation. Evidence supporting a protective role of vitamin E after contraction-induced muscle injury in humans is, however, inconsistent. The present study sought ...
Chanoit G P - - 2002
Changes in plasma creatinine (Pl-Creat), glucose, total proteins (Pl-TP), creatine kinase (Pl-CK), lactate dehydrogenase, aspartate aminotransferase and packed cell volume were evaluated in untrained Beagle dogs before, during and after a 60 min race at an average speed of 9 km/h. There was no major effect of exercise on those ...
Webster Anthony L - - 2002
OBJECTIVE: To determine whether hyperbaric oxygen (HBO) therapy could accelerate recovery from exercise-induced muscle damage in humans. DESIGN: Pretest-posttest design with random assignment to either a treatment (HBO) or placebo control (sham) group. SETTING: University of Alberta and Misericordia Hospital, Edmonton. PARTICIPANTS: 12 healthy male students (24.2 +/- 3.2 years) ...
Byrne Christopher - - 2002
In this study, we assessed the effect of exercise-induced muscle damage on knee extensor muscle strength during isometric, concentric and eccentric actions at 1.57 rad x s(-1) and vertical jump performance under conditions of squat jump, countermovement jump and drop jump. The eight participants (5 males, 3 females) were aged ...
O'Connor Patrick J - - 2002
PURPOSE: The primary aim was to describe perceived exertion responses to different intensities of eccentric exercise in women and men. METHODS: 42 adults (21 men and 21 women, 7 per condition) completed elbow extension exercises with a weight corresponding to 80%, 100%, or 120% of maximal voluntary concentric strength. Total ...
Shave Robert - - 2002
PURPOSE: The purpose of the present study was to examine the cardiospecificity of cTnI and the new third-generation cTnT assay, in the presence of exercise-induced muscle damage in highly trained individuals, and to examine the impact of a maximal-ramping treadmill test on cardiac function. METHODS: Eight highly trained male triathletes ...
Bajaj Prem - - 2002
Mechanomyography (MMG) and electromyography (EMG) recordings from the first dorsal interosseous muscle of the hand were compared for pre-exercise and immediately after, 24-hour, and 48-hour postexercise muscle soreness. Thirteen healthy male subjects performed progressively increasing number of eccentric contractions from bout 1 (10.34 +/- 1.96) to bout 6 (27.46 +/- ...
Carson Richard G - - 2002
Fatigue was induced in the triceps brachii of the experimental arm by a regimen of either eccentric or concentric muscle actions. Estimates of force were assessed using a contralateral limb-matching procedure, in which target force levels (25 %, 50 % or 75 % of maximum) were defined by the unfatigued ...
Rudolph G - - 2002
PURPOSE: To demonstrate the possibility of topographic mapping of retinal function under simultaneous control of fixation in humans, by scanning laser ophthalmoscope evoked multifocal electroretinography (SLO-m-ERG). METHODS: A confocal scanning laser ophthalmoscope was used as a stimulator and trigger unit to take m-ERGs. Short m-sequences based on a modified algorithm ...
Cleary Michelle A - - 2002
OBJECTIVE: To determine the temporal pattern of the repeated bout effect of eccentric exercise on perceived pain and muscular tenderness associated with delayed-onset muscle soreness (DOMS). DESIGN AND SETTING: Subjects completed 2 identical eccentric exercise bouts separated by 6, 7, 8, or 9 weeks. The experiment was conducted in a ...
Lee Joohyung - - 2002
PURPOSE: This study examined the effects of a single bout of high-intensity eccentric exercise (EE) on blood protein carbonyls, glutathione status, and muscle damage indicators to ascertain whether blood markers of oxidative stress are elevated at the time delayed onset of muscle soreness (DOMS) occurs. METHODS: Eight healthy men (26.5 ...
Doan Brandon K - - 2002
The purpose of this study was to measure the effects of additional eccentric loading on subsequent concentric strength. Eight subjects with some experience in weight training volunteered to perform maximal attempts in the barbell bench press using detaching hooks that allowed them to lower 105% of their concentric 1 repetition ...
Trappe Todd A - - 2002
We measured titin and nebulin content in muscle biopsies from the vastus lateralis before and 24 h after one bout of high-intensity eccentric knee extensor resistance exercise in seven men (26 +/- 3 years). Titin and nebulin content were significantly (P < 0.05) reduced after exercise by 30 and 15%, ...
Nosaka K - - 2002
This study developed an electrical stimulation model for human elbow flexors to examine eccentric exercise-induced muscle damage and adaptation. Male students (n=17) were randomly placed into one of two groups; isometric (ES-ISO, n=8) and eccentric (ES-ECC, n=9). The elbow joint was fixed at 90 degrees (1.57 rad) and the elbow ...
Nosaka Kazunori - - 2002
This study examined whether performing repeated bouts of eccentric exercise 2 and 4 days after an initial damaging bout would exacerbate muscle damage. One arm performed 3 sets of 10 eccentric actions of the elbow flexors (ECC1) using a dumbbell set at 50% of the maximal isometric force at 90 ...
Volek Jeff S - - 2002
We examined the influence of L-carnitine L-tartrate (LCLT) on markers of purine catabolism, free radical formation, and muscle tissue disruption after squat exercise. With the use of a balanced, crossover design (1 wk washout), 10 resistance-trained men consumed a placebo or LCLT supplement (2 g L-carnitine/day) for 3 wk before ...
Nosaka Kazunori - - 2002
PURPOSE: The purpose of this study was to compare changes in muscle damage indicators following 24 maximal eccentric actions of the elbow flexors (Max-ECC) between the arms that had been previously trained either eccentrically or concentrically for 8 wk. METHODS: Fifteen subjects performed three sets of 10 repetitions of eccentric ...
Thompson H S - - 2002
Exercise-induced damage significantly and predictably alters indirect indicators of muscle damage after one bout of damaging exercise but this response is dampened following a second bout of the same exercise performed 1-6 weeks later. Previously we have described a marked increase in the levels of heat shock proteins (HSPs) HSP27 ...
Mesa José L M - - 2002
Creatine is the object of growing interest in the scientific literature. This is because of the widespread use of creatine by athletes, on the one hand, and to some promising results regarding its therapeutic potential in neuromuscular disease on the other. In fact, since the late 1900s, many studies have ...
Percival, Robyn Suzanne
Purpose: To examine the effects of deer antler velvet on muscular strength, performance, and markers of delayed onset muscle soreness following a 10-week resistance training period. Participants: 16 resistance-trained males (18-35) volunteered. Measures: DEXA, 1-RM, a power test, and a 70% performance trial were measured. Creatine kinase and self-reported soreness ...
Paddon-Jones D - - 2001
PURPOSE: We examined the effects of short-term beta-hydroxy-beta-methylbutyrate (HMB) supplementation on symptoms of muscle damage following an acute bout of eccentric exercise. METHODS: Non-resistance trained subjects were randomly assigned to a HMB supplement group (HMB, 40mg/kg bodyweight/day, n = 8) or placebo group (CON, n = 9). Supplementation commenced 6 ...
Proske U - - 2001
In eccentric exercise the contracting muscle is forcibly lengthened; in concentric exercise it shortens. While concentric contractions initiate movements, eccentric contractions slow or stop them. A unique feature of eccentric exercise is that untrained subjects become stiff and sore the day afterwards because of damage to muscle fibres. This review ...
Clarkson P M - - 2001
Investigations using animal models show that estrogen is related to enzyme release, specifically creatine kinase, from exercised skeletal muscle. In humans, women have lower resting blood creatine kinase levels than men and have an attenuated blood creatine kinase response after prolonged endurance exercise. These results have led to the common ...
Eijnde B O - - 2001
A double-blind randomized study was performed to evaluate the effect of oral ribose supplementation on repeated maximal exercise and ATP recovery after intermittent maximal muscle contractions. Muscle power output was measured during dynamic knee extensions with the right leg on an isokinetic dynamometer before (pretest) and after (posttest) a 6-day ...
Matheson J W - - 2001
PURPOSE: The aim of this study was to quantify and compare mean quadriceps muscle activity and applied load for eight seated quadriceps exercises using four types of resistance. METHODS: Using surface electromyography (EMG), the right rectus femoris (RF), vastus lateralis (VL), and vastus medialis oblique (VMO) muscles of 52 university ...
Stupka N - - 2001
Eccentrically biased exercise results in skeletal muscle damage and stimulates adaptations in muscle, whereby indexes of damage are attenuated when the exercise is repeated. We hypothesized that changes in ultrastructural damage, inflammatory cell infiltration, and markers of proteolysis in skeletal muscle would come about as a result of repeated eccentric ...
Kilmer D D - - 2001
Although the response to intense eccentric muscle contractions is well described in normal subjects, concern exists about possible untoward effects in persons with myopathic diseases. We investigated 14 subjects with slowly progressive muscular dystrophies including myotonic muscular dystrophy (n = 9), facioscapulohumeral dystrophy (n = 2), limb-girdle syndrome (n = ...
Chanoit G P - - 2001
OBJECTIVE: To assess the effects of moderate exercise on plasma creatine kinase (CK) pharmacokinetics and to estimate exercise-induced muscle damage in dogs. ANIMALS: 6 untrained adult Beagles. PROCEDURE: The study was divided into 3 phases. In phase 1, dogs ran for 1 hour at a speed of 9 km/h, and ...
Kraemer W J - - 2001
The purpose of this study was to investigate the potential differences in peak isokinetic concentric end eccentric torque following low- and high-intensity cycle exercise fatigue protocols. Ten healthy, recreationally-active men were tested in a balanced, randomized testing sequence for peak eccentric and concentric isokinetic torque (60 degrees/sec) immediately before and ...
KlapciƄska B - - 2001
BACKGROUND: High intensity exercise may induce muscle damage especially in individuals unaccustomed to regular physical efforts. Our aim was to compare the impact of 300 m sprint running on muscle enzymes release into blood in competitive hurdlers and untrained but physically fit adults. METHODS: EXPERIMENTAL DESIGN: Comparative study. SETTING: General ...
Durstine J L - - 2001
PURPOSE: Most studies that use either a single exercise session, exercise training, or a cross-sectional design have failed to find a relationship between exercise and plasma lipoprotein(a) [Lp(a)] concentrations. However, a few studies investigating the effects of longer and/or more strenuous exercise have shown elevated Lp(a) concentrations, possibly as an ...
Sorichter S - - 2001
The aim of this study was to examine the relationship between myosin heavy chain (MHC) release as a specific marker of slow-twitch muscle fibre breakdown and magnetic resonance imaging (MRI) of skeletal muscle injury after eccentric exercise. The effects of a single series of 70 high-intensity eccentric contractions of the ...
Carter A - - 2001
This study tested the hypothesis that estrogen levels of women influences the development of a muscle-tissue damage (creatine kinase, CK) marker and delayed onset muscle soreness (DOMS) following eccentric exercise. Seventeen oral contraceptive (OC) users and ten eumenorrheic (EU) subjects completed a 30-min downhill running bout at approximately 60% VO2max. ...
Nosaka K - - 2001
PURPOSE: One bout of eccentric exercise produces an adaptation that reduces muscle damage in subsequent bouts. Because it is not known how long this adaptation lasts, the present study investigated the maximal length of the attenuated changes in muscle damage indicators after high-force eccentric exercise. METHODS: Male students (N = ...
Baldwin A C - - 2001
BACKGROUND: Aging is associated with greater susceptibility to muscle injury and soreness after exercise. Although elderly persons regularly consume nonsteroidal anti-inflammatory drugs (NSAIDs), it is not clear that NSAIDs alleviate muscle dysfunction and/or inflammation following injurious exercise. METHODS: In this double-blind crossover study, 10 men and 5 women (aged 60 ...
Nosaka K - - 2001
In this study we investigated the extent to which an initial eccentric exercise consisting of two (2ECC) or six maximal eccentric actions (6ECC) of the elbow flexors would produce a similar effect to 24 maximal eccentric actions (24ECC), on a second bout of 24ECC performed 2 weeks later. Male students ...
Hortobágyi T - - 2001
PURPOSE: According to the force-velocity relationship of human skeletal muscle, the maximal load one can lift is limited by the concentric movement phase, and the eccentric phase is always underloaded. In the present study, we hypothesized that acute exercise training using an eccentric overload compared with standard loading would lead ...
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