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Al-Asoom L I LI Physiology Department, College of Medicine, University of Dammam, P.O. Box 2114, Ad Dammām, 31451, Saudi Arabia, - - 2014
Exercise training is employed as supplementary therapy to patients with heart failure due to its multiple beneficial cardiac effects including physiological remodeling of the heart. However, precautions might be taken for the concomitant high oxidant release. Nigella sativa (NS) has been found to induce cardiac hypertrophy and enhance cardiac function. ...
Lagundžin Dragana - - 2013
Physical activity is accompanied by the changes in Insulin-like Growth Factor I (IGF-I)/IGF-Binding Protein 1 (IGFBP-1) axis. Inconsistent results concerning IGF-I and IGFBP-1 levels were reported. In this study we have raised some questions on the events that occur at the molecular level of the exercise-related IGFBP-1 changes. We have ...
Sánchez-Gurmaches J - - 2013
Herein, we studied whether sustained exercise positively affects growth of gilthead sea bream by alterations in a) plasma concentrations of insulin and IGF-I, b) signaling pathways in muscle, or c) regulation of lipid metabolism. Specifically, we evaluated the effects of moderated swimming (1.5 body lengths per second; BL/s) on the ...
Fain John N - - 2013
Exercise training elevates circulating irisin and induces the expression of the FNDC5 gene in skeletal muscles of mice. Our objective was to determine whether exercise training also increases FNDC5 protein or mRNA expression in the skeletal muscles of pigs as well as plasma irisin. Castrated male pigs of the Rapacz ...
Mason Caitlin - - 2013
Background: We hypothesized that weight loss induced by a diet and/or exercise would reduce IGF-1 in humans. Methods: 439 overweight/obese (BMI ≥25kg/m2) post-menopausal women (50-75 y) were randomly assigned to: i) exercise (N=117), ii) dietary weight-loss (N=118), iii) diet + exercise (N=117), or iv) control (n=87). The diet intervention was ...
Vissing K - - 2013
The influence of adenosine mono phosphate (AMP)-activated protein kinase (AMPK) vs Akt-mammalian target of rapamycin C1 (mTORC1) protein signaling mechanisms on converting differentiated exercise into training specific adaptations is not well-established. To investigate this, human subjects were divided into endurance, strength, and non-exercise control groups. Data were obtained before and ...
Karabulut Murat - - 2013
The goal of this study was to examine anabolic hormone, muscle damage marker and inflammation marker responses to two types of resistance training protocols in older men. Thirty-six healthy older males (mean age = 56·6 ± 0·6 years) completed 6 weeks of high-intensity resistance training (HI-RT), low-intensity resistance training with vascular restriction (LI-BFR) or no exercise ...
Lagundzin Dragana - - 2013
Physical activity is accompanied by the changes in insulin-like growth factor I (IGF-I)/IGF-binding protein 1 (IGFBP-1) axis. Inconsistent results concerning IGF-I and IGFBP-1 levels were reported. In this study we have raised some questions on the events that occur at molecular level of the exercise-related IGFBP-1 changes. We have examined ...
Gallagher Philip M - - 2013
The effects of resistance exercise on fiber-type-specific expression of insulin-like growth factor I receptor (IGF-1R) and glucose transporter 4 (GLUT4) was determined in 6 healthy males. The expression of both genes increased in Type I fibers (p < 0.05), but only GLUT4 increased (p < 0.05) in Type II fibers. ...
Velloso C P - - 2013
OBJECTIVE: Recombinant human growth hormone (rhGH) is used by some athletes and body builders with the aim of enhancing performance, building muscle and improving physique. Detection of the misuse of rhGH has proved difficult for a number of reasons. One of these is the effect of preceding exercise. In this ...
Hatipoglu Esra - - 2013
In acromegaly the impact of therapy on well-being and self-perception of patients is not clearly defined. The data existing on the effect of treatment on health-related quality of life in patients with acromegaly is inconclusive. In this study we addressed the effect of exercise on health-related quality of life, symptoms ...
Aucouturier Julien - - 2013
Our purpose was to investigate the effect of obesity in prepubertal children on the hormonal response to exercise performed under different conditions of nutrient availability. Prepubertal obese (age, 10.3 ± 1.8 years; %body fat, 36.1 ± 6.1; n = 9) and lean (age, 9.2 ± 1.6 years; %body fat, 22.2 ...
Chyu Ming-Chien MC Graduate Healthcare Engineering, Whitacre College of Engineering, Texas Tech University, Lubbock, - - 2013
Various exercise interventions have been shown to benefit weight control and general health in different populations. However, very few studies have been conducted on martial arts exercise (MAE). The objective of this pilot study is to evaluate the efficacy of 12 weeks of MAE intervention on body composition, serum biomarkers ...
Kawai M - - 2012
REASONS FOR PERFORMING STUDY: Although satellite cells are well known as muscle stem cells capable of adding myonuclei during muscle repair and hypertrophy, the response of satellite cells in horse muscles to a run to exhaustion is still unknown. OBJECTIVES: To investigate the time course of satellite cell activation in ...
Gregory Sara M - - 2012
INTRODUCTION: This study examined the effects of short-term physical training on the acute hormonal response (i.e. growth hormone [GH], total and free IGF-I, and IGFBP-1, -2, and -3) to resistance exercise (RE) in women. METHODS: Forty six women (20.3 ± 0.3 y, mass 64.1 ± 7.3 kg, height 165.7 ± ...
Nindl Bradley C - - 2012
IGF-I resides across different biocompartments (blood, interstitial fluid (ISF) and muscle). Whether circulating IGF-I responses to exercise reflect local events remains uncertain. We measured the IGF-I response to plyometric exercise across blood, ISF, and muscle biopsy from the vastus lateralis. 20 volunteers (8 men, 12 women, 22±1 yr) performed 10 ...
Yu Fang - - 2012
Background: The subjective experience of participating in aerobic exercise is unknown in Alzheimer's disease (AD). Objective: The purpose of this study was to understand the subjective perceptions of the feasibility and impact of a 6-month, moderate-intensity aerobic exercise intervention by older adults with AD and their family caregivers. Methods: Ten ...
Marquez David X - - 2012
Few studies have been conducted on physical activity (PA) in older caregivers, a population at risk for mental and physical decline. To assess and compare PA, PA preferences, psychosocial determinants of PA, and mental health indicators between older non-exercising caregivers and non-caregivers. Caregivers (N = 24) and non-caregivers (N = 48) ...
Yao Lan - - 2012
Whether persons with dementia benefit from fall prevention exercise is unclear. Applying the Positive Emotion-Motivated Tai Chi protocol, preliminary findings concerning adherence and effects of a dyadic Tai Chi exercise program on persons with Alzheimer's disease (AD) are reported. Using pre/posttest design, 22 community-dwelling AD-caregiver dyads participated in the program. ...
Greenwood Benjamin N - - 2011
Voluntary exercise reduces the incidence of stress-related psychiatric disorders in humans and prevents serotonin-dependent behavioral consequences of stress in rodents. Evidence reviewed herein is consistent with the hypothesis that exercise increases stress resistance by producing neuroplasticity at multiple sites of the central serotonergic system which all help to limit the ...
Dischl B - - 2011
During recovery from a maximal or submaximal aerobic exercise, augmentation of central (aortic) systolic pressure by reflected pressure waves is blunted in healthy humans. However, the extent to which reflected pressure waves modify the central pulse in diastole in these conditions remains unknown. We evaluated systolic and diastolic central reflected ...
Heck Thiago Gomes - - 2011
Integrative physiology studies have shown that immune system and central nervous system interplay very closely towards behavioural modulation. Since the 70-kDa heat shock proteins (HSP70s), whose heavy expression during exercise is well documented in the skeletal muscle and other tissues, is also extremely well conserved in nature during all evolutionary ...
Hilty Lea - - 2011
We investigated the influence of spinal opioid receptor-sensitive muscle afferents on cortical changes following fatiguing unilateral knee-extensor exercise. On separate days, seven subjects performed the identical five sets of intermittent isometric right-quadriceps contractions, each consisting of eight submaximal contractions [63±7% maximal voluntary contraction (MVC)] and one MVC. The exercise was ...
Noakes Timothy David - - 2011
In 1923, Nobel Laureate A.V. Hill proposed that maximal exercise performance is limited by the development of anaerobiosis in the exercising skeletal muscles. Variants of this theory have dominated teaching in the exercise sciences ever since, but 90 years later there is little biological evidence to support Hill's belief, and much ...
Kowalik S - - 2011
The effect of interval vs. continuous exercise on plasma leptin and ghrelin concentration in young Standardbred horses was studied. The experiment was conducted on 27 trotters, in the age between 2 and 3 years. They were divided into two groups according to the type of exercise. Blood samples were collected ...
Ferreira Aparecido Pimentel - - 2011
Postprandial lipemia is characterized by an increased concentration of circulating lipids after fat intake and is an independent risk factor for cardiovascular disease. Exercise is known to reduce postprandial lipemia and its negative clinical outcomes. This study investigated the effect of intense intermittent versus moderate continuous exercise using the same ...
Makimoto Hisaki - - 2010
The goal of this study was to evaluate the prevalence and the clinical significance of ST-segment elevation during recovery from exercise testing. During recovery from exercise testing, ST-segment elevation is reported in some patients with Brugada syndrome (BrS). Treadmill exercise testing was conducted for 93 patients (91 men), 46 ± ...
Rethorst Chad D - - 2010
Exercise is effective in the alleviation of depressive symptoms and may have physiological effects similar to those of selective serotonin reuptake inhibitors (SSRI). Recent research has identified the difference in treatment effects across genetic polymorphisms of the serotonin transporter polymorphic region (5-HTTLPR), in which the l allele has been associated ...
Stone Peter H - - 2010
The purpose of this explanatory analysis was to investigate the relationship between ST-segment depression and the rate-pressure product (RPP) during exercise to determine whether ranolazine's mechanism of action was related to a reduction in myocardial oxygen demand or preservation of myocardial oxygen supply. In patients with stable ischemic heart disease, ...
Petrie C J - - 2010
A male smoker already on atenolol therapy, presented with chest pain and dramatic exercise induced ST segment elevation. Coronary angiography demonstrated non-obstructive disease and treatment with diltiazem abolished ST segment elevation on subsequent exercise testing.
Maganis Jonathan C - - 2010
It is well recognized that ST-segment depression is due to subendocardial ischemia secondary to an increase in left ventricular end-diastolic pressure. The increase in left ventricular end-diastolic pressure is associated with increased left atrial pressure, resulting in left atrial wall distension that contributes to increasing P-wave duration (PWD). The objective ...
Rich Jonathan D - - 2010
ST-segment depression during stress testing predicts future risk for adverse cardiovascular events and routinely prompts further noninvasive imaging or invasive evaluation for coronary artery disease (CAD). A subset of patients develop ST depression at peak exercise that rapidly resolves early in the recovery period (ST-rapid). The goal of this study ...
Shaikh Ayaz Hussain - - 2010
OBJECTIVE: To determine the association of prolonged ST segment depression after an exercise test with severity of coronary artery disease. METHODS: A cross sectional study of 100 consecutive patients referred to the cardiology laboratory for stress myocardial perfusion imaging (MPI) conducted between April-August 2008. All selected patients were monitored until ...
Michaelides Andreas P - - 2010
Exercise testing (ET) stands as one of the most easy, affordable, cost effective, non invasive methods for diagnosing coronary heart disease. Its sensitivity, specificity and prognostic value, especially in the prime era of its implementation in the cardiac diagnostic procedure, is relatively limited. Novel exercise criteria and indices based either ...
Stein Ricardo - - 2010
Exercise-induced (EI) right bundle branch block (RBBB) is an infrequent electrocardiographic phenomenon, and controversy exists regarding its association with cardiovascular disease. We compared the prevalence and prognostic significance of RBBB, abnormal ST depression, and normal electrocardiographic findings in response to exercise testing in 9,623 consecutive veterans who underwent exercise testing ...
Curtis Jeffrey M - - 2010
We examined maximal graded exercise test (GXT) results in 5,783 overweight/obese men and women, aged 45-76 years, with type 2 diabetes, who were entering the Look AHEAD (Action for Health in Diabetes) study, to determine the prevalence and correlates of exercise-induced cardiac abnormalities. Participants underwent symptom-limited maximal GXTs. Questionnaires and ...
Hasan-Ali H - - 2010
To determine the best combination of parameters that would improve the diagnostic performance of exercise testing, coronary angiography plus exercise testing were done on 112 patients with angina pectoris and normal electrocardiogram. The univariate predictors of coronary artery disease included: age > or = 40 years, male sex, hypertension, smoking, ...
Zwart Bastiaan - - 2010
Although (very) late coronary stent thrombosis is a rare complication after percutaneous coronary interventions (PCI), its consequences are devastating with a high morbidity and mortality. Previous studies have identified several clinical, procedural and angiographic characteristics that are associated with stent thrombosis but little is known about the underlying mechanisms that ...
Baker Julien S - - 2010
High-intensity exercise can result in up to a 1,000-fold increase in the rate of ATP demand compared to that at rest (Newsholme et al., 1983). To sustain muscle contraction, ATP needs to be regenerated at a rate complementary to ATP demand. Three energy systems function to replenish ATP in muscle: ...
Lipinski Michael J - - 2009
BACKGROUND: While the role of hemoglobin in heart failure and renal disease has been investigated, little is known about its effect on clinical exercise test performance and mortality in patients referred for routine exercise treadmill testing (ETT). HYPOTHESIS: Patients with low hemoglobin will have poor exercise capacity and would be ...
Hughes Carroll W - - 2009
There is an important need for non-medication interventions for depressed youth. The aim of this study is to evaluate the feasibility of using a standardized aerobic exercise regime to treat non-medicated clinically depressed adolescents based on adherence and completion rates, including 1) establishing effect sizes for the primary outcomes including ...
Kronander Håkan - - 2010
Exercise electrocardiography is widely used for initial identification of patients with coronary artery disease (CAD). This study compares the measurements of ST-segment changes during exercise and during early postexercise recovery in terms of diagnostic discrimination capacity and optimal partition values. Data from 1876 patients undergoing a routine bicycle exercise test ...
Michaelides Andreas P - - 2010
BACKGROUND: The appearance of a discrete upward deflection of the ST segment, termed the ST hump sign during exercise testing has been associated with resting hypertension and exaggerated blood pressure response to exercise. OBJECTIVE: We investigated the correlation between the presence of hump sign during exercise testing with coexisting impaired ...
Juneau Martin - - 2009
Current guidelines for exercise training in coronary patients state that in the presence of exercise-induced ischemia, the heart rate during exercise should be at least 10 beats/min below the heart rate associated with an ST segment depression of 1 mm or greater. For patients with a relatively low ischemic threshold, ...
Palevo Gregory - - 2009
PURPOSE: This study determined the effect of a structured isotonic strength training (ST) program on left ventricular (LV) function (ejection fraction, stroke volume, and end-diastolic and end-systolic volumes) and physical fitness (6-minute walk test, upper body strength, lower body strength, and body composition) in patients with New York Heart Association ...
Sordi Martina - - 2009
Exercise-induced ST-segment elevation in patients without previous myocardial infarction is a relatively uncommon finding. When it does occur, it may be associated with significant coronary artery disease or coronary vasospasm. Here we describe a case of exercise-induced ST-segment elevation in both anterior and inferior leads in a patient with a ...
Wang Ningfu - - 2009
Hepatocyte growth-promoting factor (pHGF) has the greatest potential as a therapeutic agent for vascular growth factor. The aim of this study was to investigate the effect of pHGF on myocardial ischemia and exercise capacity in patients with severe coronary artery disease (CAD). Forty-nine patients were enrolled for a two week ...
Michaelides Andreas P - - 2009
BACKGROUND: The appearance of a discrete upward deflection of the ST segment termed "the ST hump sign" (STHS) during exercise testing has been associated with resting hypertension and exaggerated blood pressure response to exercise. OBJECTIVE: We investigated the prevalence and clinical significance of this sign in a population of patients ...
de Abreu Samantha Bagolan - - 2009
The paraventricular nucleus (PVN) of the hypothalamus is an important site for autonomic regulation, where gamma-aminobutyric acid (GABA) system plays an important role. The central mechanisms underlying modulatory effects of exercise training have yet to be characterized. Our objective was to analyze the effects on the autonomic modulation and hemodynamic ...
Michaelides Andreas P - - 2009
PURPOSE: It is well known that patients with arterial hypertension frequently present with ischemic electrocardiographic changes during exercise testing without actually having coronary artery disease (CAD). The purpose of this study was to establish additional electrocardiographic criteria during exercise testing for detecting CAD in hypertensive patients with ischemic ST-segment response. ...
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