Search Results
Results 401 - 450 of 923
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Matsubara K - - 1995
We compared cardiohemodynamic response to dynamic exercise in 32 patients with exercise-induced silent or symptomatic myocardial ischemia. All patients had coronary artery disease without prior myocardial infarction and left ventricular hypertrophy. Patients underwent supine leg-exercise testing and received right heart catheterization. All patients exhibited ischemic ST-segment depression on electrocardiogram during ...
Taylor A J - - 1995
This study sought to determine the relation between the magnitude of exercise-induced ST depression and the ischemic burden as determined by quantitative thallium-201 scintigraphy. One hundred forty-four consecutive patients were prospectively studied with symptom-limited exercise testing and thallium-201 scintigraphy. Of these patients, 37 had between 1.0 and < 2.0 mm ...
Cha K - - 1995
Multifrequency bioelectrical impedance analysis (MFBIA) was used to determine the intracellular (ICW) and extracellular water (ECW) compartments in rats. Resistance and reactance were measured on various body segments with frequencies ranging from 1 KHz to 1 MHz. After initial measurements, 0.9% NaCl was injected intravenously or intraperitoneally, and changes in ...
Rauramaa R - - 1995
The association between cardiorespiratory fitness (VO2max) and carotid atherosclerosis was analyzed in 163 men, aged 50 to 60 years. VO2max was assessed using breath-by-breath respiratory gas analyses during maximal exercise stress test. Atherosclerosis was evaluated quantitatively as intima-media thickness (IMT) of the right and left carotid arteries by high-resolution B-mode ...
Colasurdo G N - - 1994
We investigated the functional existence of the nonadrenergic noncholinergic inhibitory (NANCi) system in developing rabbit airways in vitro. Furthermore, we evaluated the effect of parenteral exposure to a specific allergen (ragweed) on the maturation of this neural pathway. NANCi responses were studied on tracheal smooth muscle (TSM) segments obtained from ...
Lanza G A - - 1994
BACKGROUND: Sublingual nitrates are much more effective in relieving angina pectoris in patients with coronary artery disease than in patients with syndrome X, but it is not known whether their effect on exercise tolerance is also different in these two groups of patients. METHODS AND RESULTS: Treadmill exercise testing was ...
Paul S D - - 1994
Myocardial ischemia is an indicator of adverse prognosis. In patients with stable angina and positive exercise tests, prolonged cumulative ischemia on ambulatory electrocardiographic monitoring identifies a high-risk group with severe coronary artery disease and poor survival. To determine whether features of the exercise test can accurately (1) predict the occurrence ...
Chou M M - - 1994
OBJECTIVE: Our purpose was to compare intramyometrial 15-methyl prostaglandin F2 alpha with intravenous oxytocin for controlling blood loss at elective cesarean section. STUDY DESIGN: A double-blind, randomized trial was performed with intramyometrial 15-methyl prostaglandin F2 alpha, 125 micrograms, or intravenous oxytocin, 20 U, in 60 women undergoing elective lower segment ...
Katori R - - 1994
Changes in hemodynamics and plasma norepinephrine levels during supine bicycle exercise after myocardial infarction were measured to investigate the mechanism of exercise-induced ST-segment elevation. Seventy-eight patients were divided into groups which showed either ST elevation (STE), ST depression (STD), or no ST changes (STU). Most of the STE group had ...
Kochiadakis G E - - 1994
INTRODUCTION: Transtelephonic electrocardiographic transmission is a diagnostic technique which has been systematically applied in recent years, mainly for the detection of arrhythmias or pacemaker malfunction. The purpose of this study was to assess the efficacy of this method in the recording and transmission of ST segment and T wave changes. ...
Bigi R - - 1994
The demonstration of extensive coronary artery disease (CAD) after acute myocardial infarction (AMI) has important prognostic implications. Exercise-induced ST segment depression is commonly used for detecting the presence of CAD and evaluating its extension. However, even though there have been many attempts to increase its diagnostic yield, the accuracy of ...
Arstall M A - - 1994
BACKGROUND: In individuals with no known ischaemic heart disease, the prevalence and significance of ST-segment depression on ambulatory electrocardiographic monitoring is unclear. We therefore determined the prevalence of ST-segment depression among middle-aged male police officers, an occupational group in whom an increased risk of ischaemic heart disease has been reported, ...
Lan X - - 1994
To assess the ability of 3 established analysis methods in exercise stress electrocardiography to non-invasively detect the presence of coronary artery disease (CAD), 67 consecutive patients who had typical angina, positive exercise stress electrocardiography (ST segment depression > or = 1 mm) and coronary arteriography were studied. Thirty-three patients had ...
Rossetti E - - 1994
Diazepam (DZP) is commonly used in treatment of patients with acute ischemic syndromes to allay anxiety, but benzodiazepines reduce myocardial contractility and increase myocardial blood flow. To investigate the antiischemic effect of DZP, we studied 13 patients with a positive exercise test and angiographically documented coronary artery disease. All patients ...
Entwistle M D - - 1994
The effect of hypoxaemia on the heart at rest was studied using the electrocardiogram (ECG) in 38 patients. The majority had symptoms of cardiac disease and all were scheduled to have an exercise ECG test under standard conditions. Two ECG variables were examined; (i) depression of the ST segment at ...
Medbø J I - - 1994
Active muscle releases K+, and the plasma K+ concentration is consequently raised during exercise. K+ is removed by the Na,K pump, and training may influence the number of pumps. The plasma K+ concentration was therefore studied in five endurance-trained (ET) and six sprint-trained (ST) subjects during and after 1 min ...
Michaelides A P - - 1994
Two patients with coronary artery disease appearing as "walkthrough" angina underwent a treadmill exercise test. During the exercise, the patients appeared to have anginal pain associated with ST-segment depression and increased QRS duration. As the patients continued walking, anginal pain disappeared and a concomitant lessening in ST-segment depression and QRS ...
Mazzotta G - - 1994
BACKGROUND: In 183 patients with uncomplicated myocardial infarction, exercise-induced angina, ST segment depression, decrease in ejection fraction, or inadequate increase in systolic blood pressure and low exercise tolerance were significantly associated with 4-year incidence of hard ischemic events. METHODS AND RESULTS: Only the onset of both ST segment depression and ...
Klein J - - 1994
BACKGROUND: The clinical significance of exercise-induced chest pain remains controversial, as reflected by sharply discordant clinical results within the medical literature. Thus, we developed a prospective study to compare the functional significance of silent versus symptomatic ischemia and to evaluate whether patient selection biases influence this analysis. METHODS AND RESULTS: ...
Luurila O J - - 1994
To evaluate the occurrence of arrhythmias and silent ischaemia during a prolonged exhaustive exercise in cold climate conditions, we monitored 37 healthy middle-aged men (age 40-56 years) who were randomly selected from participants of a ski marathon. Completing the 75-90 km race took 7-12 h. The highest and lowest mean ...
Chester A H - - 1994
A study was performed to investigate the duration of action of papaverine applied either intraluminally or in a combined intraluminal and extraluminal fashion in vitro, and how the reactivity of the internal mammary artery (IMA) to a range of vasoconstrictors is affected. Segments of IMA exposed to only intraluminal papaverine ...
Brockmeier K - - 1994
Twenty healthy male subjects (age range, 15-25 years; median, 21 years) underwent magnetocardiography during physical exercise. Significant ST-segment displacements of the magnetic signal were found during exercise at a heart rate of 120 beats/min compared to the magnetic signal at rest (P < .001). Since no significant ST-segment changes were ...
Okin P M - - 1994
Determinants of the ST-segment response to exercise can be mathematically modeled by solid-angle theory, and heart rate adjustment of the magnitude of exercise-induced ST-segment depression can remodel the solid-angle relationship to provide a theoretic and practical basis for application of heart rate-adjusted indexes of ST depression in exercise electrocardiography. Solid-angle ...
Schedl H P - - 1994
Formulation of oral rehydration solutions (ORS) is reviewed in the context of methods for measuring absorption of water and component substrates, transport mechanisms of substrates and water, requirements of the athlete, and effects of exercise on absorption. The triple lumen tube intubation perfusion method is the optimal technique for obtaining ...
Ruf G - - 1994
The anti-ischemic effect of 5 mg nebivolol o.i.d., a newly developed beta 1-selective adrenoceptor blocking drug with vasodilating properties, was compared with that of atenolol (100 mg o.i.d.) following a treatment period of 6 days. The study was performed in 24 patients with documented coronary artery disease and stable angina ...
Kaski J C - - 1994
OBJECTIVES: This study was conducted to test the hypothesis that angiotensin-converting enzyme inhibition may lessen myocardial ischemia in patients with microvascular angina. BACKGROUND: Patients with syndrome X (angina pectoris, positive findings on exercise testing and normal coronary arteriogram) have a reduced coronary vasodilator reserve ("microvascular angina") and may show an ...
Hecht H S - - 1994
OBJECTIVES: The objectives of this study were 1) to determine the relationship between the amount of exercise-induced ischemic myocardium and the presence or absence of chest pain and ST segment depression, and 2) to define the incidence and characteristics of "truly silent ischemia," that is, ischemia that is not manifested ...
Thürmann P - - 1994
In a randomized double-blind, placebo-controlled, crossover trial, the potential anti-ischaemic action of the angiotensin-converting enzyme (ACE) inhibitor spirapril was studied in 19 patients with coronary artery disease (CAD) and reproducible exercise-induced ST-segment depression, but without hypertension or congestive heart failure. Measurements of blood pressure and heart rate as well as ...
Kedem J - - 1994
We determined the capabilities and limitations of an experimental approach to measure segment work (force x distance) of myocardial regions in the in vivo beating heart. In 18 open-chest anesthetized dogs, segment length was measured using ultrasonic dimension transducers, and developed force was measured with miniature force transducers. Work was ...
Lehtinen R - - 1994
To improve the diagnostic power of the exercise electrocardiographic test in detecting myocardial ischemia, the authors have recently developed a diagnostic method called multivariate ST-segment/heart rate (ST/HR) analysis (MUSTA). The goal of this study was to evaluate the validity of MUSTA in different clinical populations and to compare its performance ...
Rohrschneider W - - 1994
A donut-shaped intestinal structure in the lower right abdomen, observed during abdominal ultrasound investigation following nonoperative intussusception reduction, may create a diagnostic problem concerning differentiation from a residual or recurrent intussusception or underlying small bowel disease. In 30 cases of ileocolic intussusception an abdominal ultrasound examination was performed after reduction, ...
Mercier J - - 1994
We investigated whether the spontaneous transition between walking and running during moving with increasing speed corresponds to the speed at which walking becomes less economical than running. Seven active male subjects [mean age, 23.7 (SEM 0.7) years, mean maximal oxygen uptake (VO2max), 57.5 (SEM 3.3) ml.kg-1.min-1, mean ventilatory threshold (VTh), ...
Currie P - - 1994
The relative value of ambulatory ST segment monitoring for assessing prognosis following acute myocardial infarction is currently uncertain. Ambulatory monitoring was performed in 177 patients at a mean of 38 days (range 22-93) post-myocardial infarction and its prognostic value was compared with exercise treadmill testing (n = 170). Cardiac events ...
Karlsson J E - - 1993
One month after an episode of unstable coronary artery disease, 95 male patients performed coronary angiography, 48 hours ambulatory ST-recording and also an exercise test. ST-depression occurred in 29.5% during the ST-recording and in 44.2% during the exercise test (p < 0.05). In patients with ST-depression at ambulatory monitoring, 79% ...
Tousoulis D - - 1993
OBJECTIVES: This study was designed to assess the relation between rest left ventricular function and exercise capacity in patients with syndrome X. BACKGROUND: Clinical observation has suggested that some patients with syndrome X have a high rest left ventricular ejection fraction. In this study we determined the relation between left ...
Karlsson J E - - 1993
After an episode of unstable coronary artery disease, 190 patients performed a predischarge exercise test. A postdischarge exercise test and coronary angiography was performed by 172 patients after 1 month. A subgroup of 104 men performed both exercise tests with a computer-aided system. More sophisticated methods of evaluating the ECG ...
Quyyumi A A - - 1993
OBJECTIVES: The study was designed to assess the feasibility of conducting a trial to investigate whether exercise and low molecular weight heparin therapy with dalteparin sodium (Fragmin) would improve collateral function to the ischemic myocardium in patients with coronary artery disease. BACKGROUND: The severity of myocardial ischemia in patients with ...
Benhorin J - - 1993
OBJECTIVES: The aim of this study was to examine the dependence of the ischemic threshold during exercise testing on the exercise protocol employed and to determine the relation between the ischemic thresholds observed during exercise and during daily activity. BACKGROUND: The ischemic threshold (heart rate at 1-mm ST segment depression) ...
Thurkow E W - - 1993
In the literature, discussions continue on the question whether the distal portion of the cardiac outlet segment (ventriculoarterial portion, outflow tract of the embryonic heart) is subject to a shortening (absorption, retraction) during development. In 28 human embryos ranging from 4-42 mm crown-rump length, stereological estimates of volume fractions and ...
Yamabe H - - 1993
This study evaluated the clinical value of the ST/HR slope and exercise hemodynamic variables for the severity of coronary artery lesions. Twenty-nine patients with effort angina pectoris underwent ergometer exercise during right side heart catheterization. The ST/HR slope failed to differentiate three groups stratified by the number of involved coronary ...
Rodriguez M - - 1993
The objective of the study was to optimize the accuracy of the exercise test for predicting the presence of significant angiographic coronary artery disease. A retrospective analysis of stored digital exercise electrocardiographic data on 147 men who had undergone exercise testing and cardiac catheterization was performed. With significant coronary artery ...
Robertson G - - 1993
To investigate the effect of aerobic exercise on total gastrointestinal and segmental colon transit, 16 male health care workers with a sedentary life-style were studied during 1 week of rest and 1 week of exercise. The exercise phase consisted of walking 4.5 km on a level treadmill for 1 h ...
Dargie H J - - 1993
The Total Ischaemic Burden European Trial (TIBET) affords the opportunity to investigate the prognostic value of both exercise testing and ambulatory monitoring on and off medical treatment; 682 patients were followed for two years. Patients with < 1 mm ST segment depression on exercise testing have very low risk indeed ...
Haber H L - - 1993
Scant data are available concerning the application and results of exercise thallium-201 (Tl-201) scintigraphy after acute myocardial infarction (AMI) treated with thrombolytic therapy. The goals of this study were to determine the ability of exercise Tl-201 scintigraphy to detect inducible ischemia and to identify multivessel coronary artery disease (CAD) in ...
Okazaki Y - - 1993
OBJECTIVES: The aim of this study was to test the hypothesis that the warm-up phenomenon is attributable to a reduction of increased myocardial oxygen consumption rather than to increased coronary blood flow during exercise. BACKGROUND: The underlying mechanism of the warm-up phenomenon is not elucidated. METHODS: Thirteen patients with effort ...
Herreras O - - 1993
The propagation of sustained potential shifts associated with spreading depression (SD) was studied by microelectrodes placed in diverse layers at different locations in hippocampus of anesthetized rats. SD was induced by raising interstitial potassium concentration ([K+]0) focally in the CA1 region of the dorsal hippocampus either by microdialysis or by ...
Myers J - - 1993
Although important strides have been made in related procedures, exercise ECG remains an invaluable tool in the initial assessment of coronary disease and yields a great deal of prognostic information. Access to limited health care resources often hinges on its outcome. Proper methodology is critical to patient safety and to ...
Jajoo U N - - 1993
In 1983, we carried out a cross-sectional, rural community based study and highlighted an abysmally low prevalence of probable coronary heart disease in resting electrocardiogram. A seven year follow-up (1983-1990) of 179 suspects showed no morbidity or mortality from coronary heart disease. Eighty one out of 98 suspects tested negative ...
Montorsi P - - 1993
Patients with syndrome X have been found to have an abnormal coronary blood flow reserve. The physical performance during exercise, however, has been incompletely investigated. Cardiopulmonary exercise testing (CPX) is a reliable noninvasive method to provide indexes of lung, heart, circulation, and muscle functions. In 15 patients (10 women) with ...
Schmidt P - - 1993
We studied the release of immunoreactive somatostatin, VIP, and galanin during net aboral propulsive complexes (NAP) in isolated, perfused, 80-cm segments of porcine ileum. Net aboral propulsive complexes were induced by controlled infusion of liquid (perfusion medium, 3.5 ml/min) into the proximal opening of the ileum segment. In response to ...
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