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Baydemir Gözde G Department of Chemistry, Biochemistry Division, Hacettepe University, Ankara, - - 2014
A molecularly imprinted composite cryogel (MICC) was prepared for depletion of hemoglobin from human blood prior to use in proteome applications. Poly(hydroxyethyl methacrylate) based MICC was prepared with high gel fraction yields up to 90%, and characterized by Fourier transform infrared spectrophotometer, scanning electron microscopy, swelling studies, flow dynamics and ...
Kumar Naresh N Department of Orthopaedic Surgery, NUHS Tower Block, Level 11, National University Health System, Singapore, 119228, Singapore, - - 2014
Intraoperative cell salvage (IOCS) has not been widely adopted in oncological surgery due to the hypothetical concern of reinfusion of malignant cells. We evaluated the feasibility of IOCS in combination with leucocyte depletion filter (LDF) in metastatic spine tumour surgery (MSTS). Patients with known primary epithelial tumour, operated for metastatic ...
Deguchi K K Department of Mathematics, Imperial College London, South Kensington Campus, London SW7 2AZ, - - 2014
The applications and implications of two recently addressed asymptotic descriptions of exact coherent structures in shear flows are discussed. The first type of asymptotic framework to be discussed was introduced in a series of papers by Hall & Smith in the 1990s and was referred to as vortex-wave interaction theory ...
Lázaro Guillermo R GR Departament d'Estructura i Constituents de la materia, Universitat de Barcelona, Av. Diagonal 647, E08028 Barcelona, Spain. - - 2014
We study the focusing of red blood cells and vesicles in pressure-driven flows in highly confined microchannels (10-30 μm), identifying the control parameters that dictate the cell distribution along the channel. Our results show that an increase in the flow velocity leads to a sharper cell distribution in a lateral ...
Bompiani Kristin M KM Department of Surgery, Duke University Medical Center, DUMC 3704, Durham, North NC 27710, USA; University Program in Genetics and Genomics, Duke University Medical Center, DUMC Box 103855, Durham, NC 27710, - - 2014
Coordinated enzymatic reactions regulate blood clot generation. To explore the contributions of various coagulation enzymes in this process, we utilized a panel of aptamers against factors VIIa, IXa, Xa, and prothrombin. Each aptamer dose-dependently inhibited clot formation, yet none was able to completely impede this process in highly procoagulant settings. However, ...
Sharma R K RK Graduate School of Life Science, Hokkaido University, Sapporo, 060-0810, Hokkaido, - - 2014
The effects of a flow field on the amyloid fibrillogenesis of β-lactoglobulin (βLG) were investigated using a flow birefringence method and AFM imaging experiments. A 4wt % βLG aqueous solution was incubated at pH 2 and 80(∘)C. A flow field was then applied by stirring at 250 and 474rpm. An ...
Zhu Jieqing J DSAPM Lab, PCFM Lab, OFCM Institute, School of Chemistry and Chemical Engineering, Sun Yat-Sen University, Guangzhou 510275, China. - - 2014
The assemblies and transformations of dendritic polyethylene (DPE)-poly(oligo(ethyleneglycol) methacrylate) (POEGMA) amphiphilic micelles have been demonstrated by cryo-TEM and DLS techniques under elongation flow stimuli. The flow rate-dependence of the dissymmetry ratio suggests the possibility that a combination of shear and elongation could also be responsible for the transitions of DPE-POEGMAs, ...
Kornblith Lucy Z LZ From the Department of Surgery (L.Z.K., B.M.H., C.K.C., R.A.C., R.F.V., B.J.R., M.F.N., M.J.C.), San Francisco General Hospital and the University of California, San Francisco; Department of Laboratory Medicine (Y.D., S.P., M.P.B., S.P.), University of California, San Francisco; and Blood Systems Research Institute (Y.D., S.P., M.P.B., S.P.), San Francisco, - - 2014
Mounting evidence highlighting the benefits of hemostatic resuscitation has led to a renewed interest in whole blood (WB) and reconstituted WB (RWB). However, few data exist to characterize the clotting profiles of these variants. This study characterizes banked WB variants and RWB in standard 1:1:1 and 2:1:1 transfusion ratios of ...
Zhou Yang Y Key Laboratory of Industrial Ecology and Environmental Engineering (Ministry of Education), School of Environmental Science and Technology, Dalian University of Technology, Dalian, 116024, - - 2014
Soluble anthraquinone compounds including anthraquinone-2-sulfonate (AQS) and anthraquinone-2,6-disulfonate can accelerate anaerobic decolorization of azo dyes. To realize the application of these compounds, the catalytic performance and stability of AQS-modified polyurethane foam (AQS-PUF) for Reactive Red K-2G decolorization were investigated in an up-flow anaerobic bioreactor under saline conditions. The results showed ...
Fukuda Kenji K Department of Neurosurgery, National Cerebral and Cardiovascular Center, Suita, Osaka, - - 2014
To evaluate the quantitative assessment of flow dynamics during surgery for arteriovenous malformations (AVMs) with FLOW 800 using ICG videoangiography. Changes in flow dynamics in the superficial AVM components (feeder, nidus, and drainer), the adjacent cortical artery, and the cortical vein surrounding AVMs were evaluated. Analysis was performed at pre-dissection, ...
G Upendar Reddy UR Organic Chemistry Division, CSIR-National Chemical Laboratory, Pune-411008, India. - - 2014
A new Cu(ii)-complex is used as a "Turn-On" luminescence probe for specific detection of endogenous Cys in live Hct116 cells and Cys present in human blood plasma without any interference from other amino acids, especially GSH and Hcy. Difference in the mechanistic pathway for Cys and His recognition is discussed.
Sanfins Elodie - - 2014
Nanoparticles (NPs) are increasingly used in diagnostic and drug delivery. After entering the blood stream a protein corona will form around NPs. The size and curvature of NPs is one of the major characteristics affecting the composition of bound protein in the corona. Key initiators of the intrinsic pathway of ...
Veale Margaret F MF Research & Development, Australian Red Cross Blood Service, Melbourne, Victoria, - - 2014
Extended room temperature (RT) hold of whole blood (WB) may affect the quality of red blood cell (RBC) components produced from these donations. The availability of better RBC additive solutions (ASs) may help reduce the effects. A new AS, AS-7 (SOLX, Haemonetics Corporation), was investigated for improved in vitro quality ...
Lotko William W Thayer School of Engineering, Dartmouth College, Hanover, NH, USA. Research Affiliate, High Altitude Observatory, National Center for Atmospheric Research, Boulder, CO, USA. - - 2014
Observed distributions of high-speed plasma flows at distances of 10 to 30 Earth radii (R(E)) in Earth's magnetotail neutral sheet are highly skewed toward the premidnight sector. The flows are a product of the magnetic reconnection process that converts magnetic energy stored in the magnetotail into plasma kinetic and thermal ...
Imran Ul-Haq Muhammad M Centre for Blood Research, Department of Pathology and Laboratory Medicine, 2350 Health Sciences Mall, Vancouver BC, V6T 1Z3, Canada; Department of Chemistry, The University of British Columbia, Life Sciences Centre, 2350 Health Sciences Mall, Vancouver BC, V6T 1Z3, - - 2014
Multifunctional polymers with defined structure and biocompatibility are critical to the development of drug delivery systems and bioconjugates. In this article, the synthesis, in vitro blood compatibility, cell viability, in vivo circulation, biodistribution, and clearance of hybrid copolymers based on linear and branched polyglycerol are reported. Hybrid polyglycerols (M‾n ≈ 100 kDa) are ...
Chaleckis Romanas R Graduate School of Biostudies, Kyoto University, Sakyo-ku, Kyoto, - - 2014
Metabolomics, a modern branch of chemical biology, provides qualitative and quantitative information about the metabolic states of organisms or cells at the molecular level. Here we report non-targeted, metabolomic analyses of human blood, using liquid chromatography-mass spectrometry (LC-MS). We compared the blood metabolome to the previously reported metabolome of the ...
Mao Ruinan R Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL 60208, USA. - - 2014
We report in situ small-angle X-ray scattering (SAXS) studies of a cylindrically ordered styrene-ethylene butylene-styrene (SEBS) triblock copolymer melt subjected to uniaxial extensional flow. The flow is applied by stretching strips of polymer melt using a counter-rotating drum extensional flow fixture housed in a custom oven designed to provide X-ray ...
Vitry Marie-Alice MA Unité de Recherche en Biologie des Microorganismes, Laboratoire d'Immunologie et de Microbiologie, NARILIS, University of Namur (UNamur). Rue de Bruxelles 61, 5000 Namur, - - 2014
Brucella spp are facultative intracellular Gram-negative coccobacilli responsible for brucellosis, a worldwide zoonosis. We observed that Brucella melitensis is able to persist for several weeks in the blood of intraperitoneally infected mice and transferred blood at any time point tested is able to induce infection in naïve recipient mice. Bacterial ...
Ranucci Marco M Department of Cardiothoracic, Vascular Anesthesia and Intensive Care, IRCCS Policlinico San Donato, Milan, - - 2014
During the coagulation process, blood changes from a liquid to a solid gel phase. These changes are reflected by changes in blood viscosity; however, blood viscosity at different shear rates (SR) has not been previously explored during the coagulation process. In this study, we investigated the viscosity changes of whole ...
Sommerey Cora-Costanze CC Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, United Kingdom. Electronic address: - - 2014
Thromboelastography is a whole blood-based coagulation assay that can be used to investigate hypocoagulability and hypercoagulability, as seen with thromboembolic diseases and disseminated intravascular coagulation. Numerous coagulopathies due to different causes are reported in cows. The objective was to establish reference intervals for thromboelastography using the TEG 5000 (Haemonetics GmbH, ...
He Xiaoxiao - - 2014
This paper describes a sensitive and specific determination strategy for Staphylococcus aureus (S. aureus) detection using aptamer recognition and fluorescent silica nanoparticles (FSiNPs) label based dual-color flow cytometry assay (Aptamer/FSiNPs-DCFCM). In the protocol, an aptamer, having high affinity to S. aureus, was first covalently immobilized onto chloropropyl functionalized FSiNPs through ...
- - 2014
To get a larger, more holistic view of the patient flow process, a multidisciplinary improvement team at Children's Hospital of Philadelphia (CHOP) developed a five-domain patient flow scorecard. Each domain has several weighted sub-metrics that add up to 20 points, so the maximum number of points in the composite score ...
Gentile Luigi - - 2014
The formation of multilamellar vesicles (MLVs) from the lamellar phase of the non-ionic surfactant system C12E5/D2O under shear flow is studied by time resolved small angle neutron and light scattering during shear flow. A novel small angle neutron scattering sample environment enables tracking the lamellae alignment in the velocity-velocity gradient ...
Kim Hanah - - 2014
Abstract Background: The Sysmex XN (XN) modular system (Sysmex, Kobe, Japan) is a new automated hematology analyzer equipped with different principles from its previous version, Sysmex XE-2100. We compared the performances of Sysmex XN and XE-2100 in umbilical cord blood (CB) specimens. Methods: In 160 CB specimens, complete blood count ...
Cai Yunbo Y MOE Key Laboratory of Macromolecule Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China. - - 2014
A novel tetraphenylethene-based fluorescent H2S probe was designed and synthesized, which exhibited high selectivity and tuneable sensitivity, making direct indication of H2S concentration in blood and unknown samples possible.
Hashimoto Kazuki K Institute of Microbial Chemistry (BIKAKEN), Tokyo , 3-14-23 Kamiosaki, Shinagawa-ku, Tokyo 141-0021, - - 2014
An anti-selective catalytic asymmetric nitroaldol reaction was manifested in a continuous-flow platform. The requisite Nd/Na heterogeneous catalyst was readily prepared by self-assembly of an amide-based chiral ligand, NdO1/5(O(i)Pr)13/5, NaHMDS, and a multiwalled carbon nanotube without covalent linkage. A stainless-steel column filled with the Nd/Na catalyst was incorporated in a flow ...
Nguyen Phi-Hung PH College of Pharmacy, Catholic University of Daegu, Hayang, 712-702, Gyeongbuk, - - 2014
A phytochemical study of the grains of S. bicolor, resulting in the isolation of twelve flavonoid glycosides 1-12. Their chemical structures were elucidated on the basis of spectroscopic (1D and 2D NMR) and MS data analyses. All compounds were tested on thrombin time (TT) assay and α-glucosidase assay in order ...
Petersen Trine P TP Ludwig-Maximilians-Universität München, Department Chemie Butenandtstrasse 5-13, Haus F, 81377 München - - 2014
A flow procedure for the metalation of functionalized heterocycles (pyridines, pyrimidines, thiophenes, and thiazoles) and various acrylates using the strong, non-nucleophilic base TMPMgCl⋅LiCl is reported. The flow conditions allow the magnesiations to be performed under more convenient conditions than the comparable batch reactions, which often require cryogenic temperatures and long ...
Luther S K SK Lehrstuhl für Technische Thermodynamik (LTT) and Erlangen Graduate School in Advanced Optical Technologies (SAOT), Friedrich-Alexander Universität Erlangen-Nürnberg (FAU), Erlangen, Germany. - - 2014
An intensifier based Raman measuring strategy is introduced which allows for a phase-specific signal detection of one single phase in segmented flows at droplet generation frequencies of potentially up to several kHz.
Akbar Noreen - - 2014
This article deals with the influence of heat transfer and nanofluid on the peristaltic flow of a third order fluid. Numerical solutions are evaluated for temperature, nanofluid phenomenon, streamlines and pressure rise. Graphical illustrations investigate the influence of various embedded parameters. It is seen that with high buoyancy forces and ...
Pertinhez Thelma A TA CIM Laboratory, Technopole Parma, University of Parma, Parma, - - 2014
Blood transfusion is an established therapeutic practice. The characteristics of blood components at different storage times are expected to affect the efficacy of transfusion therapy. Metabolic profiling by nuclear magnetic resonance (NMR) spectroscopy requires little or no sample treatment and allows identification of more than 50 soluble metabolites in a ...
Nawrocka-Bogusz Honorata H The Department of Biophysics, Poznań University of Medical Sciences, Poznań, - - 2014
In this study we attempted to assess the effect of light of 855 nm wavelength (IR-light) on the rheological parameters of blood in vitro. As an anticoagulant, heparin was used. The source of IR-light was an applicator connected to the special generator - Viofor JPS®. The blood samples were irradiated ...
Gosiewski Tomasz - - 2014
The study describes the application of the PCR method for the simultaneous detection of DNA of Gram-negative bacteria, Gram-positive bacteria, yeast fungi and filamentous fungi in blood and, thus, a whole range of microbial etiological agents that may cause sepsis. Material for the study was sterile blood inoculated with four ...
Viallat A A Laboratoire Adhésion and Inflammation, Inserm U1067, CNRS UMR 7333, Aix-Marseille Université, Marseille, - - 2014
There is a number of publications on red blood cell deformability, that is, on the remarkable cell ability to change its shape in response to an external force and to pass through the narrowest blood capillaries and splenic sinuses. Cell deformability is postulated to be a major determinant of impaired ...
Revenfeld Anne Louise Schacht AL Laboratory for Medical Mass Spectrometry, Section for Biomedicine, Aalborg University, Aalborg, - - 2014
Extracellular vesicles (EVs) are small, membrane-enclosed entities released from cells in many different biological systems. These vesicles play an important role in cellular communication by virtue of their protein, RNA, and lipid content, which can be transferred among cells. The complement of biomolecules reflects the parent cell, and their characterization ...
Werlang T T Instituto de Física, Universidade Federal de Mato Grosso, Cuiabá MT, - - 2014
We study the effect of ultrastrong coupling on the transport of heat. In particular, we present a condition for optimal rectification, i.e., flow of heat in one direction and complete isolation in the opposite direction. We show that the strong-coupling formalism is necessary for correctly describing heat flow in a ...
Ohkubo Takeshi T College of Agriculture, Ibaraki University, Ami, Ibaraki 300-0393, Japan. Electronic address: - - 2014
Leptin is a multi-functional adipokine in vertebrates. The leptin gene and protein are found in many vertebrates; however, the existence of leptin in birds remains controversial. Here we detected leptin-like activity in avian blood using chicken leptin receptor (chLEPR) and green fluorescent protein (GFP)-fused chicken signal transducer and activator of ...
Chung Henry H HH Department of Biomedical Engineering, University of Rochester, Rochester, NY, USA. - - 2014
Microfluidic systems are powerful tools for cell biology studies because they enable the precise addition and removal of solutes in small volumes. However, the fluid forces inherent in the use of microfluidics for cell cultures are sometimes undesirable. An important example is chemotaxis systems where fluid flow creates well-defined and ...
Minasyan Hayk H Yerevan - - 2014
It is an axiom that blood cellular immunity is provided by leukocytes. As to erythrocytes, it is generally accepted that their main function is respiration. Our research provides objective video and photo evidence regarding erythrocyte bactericidal function. Phase-contrast immersion vital microscopy of the blood of patients with bacteremia was performed, ...
Fambri Francesco F Department of Physics, University of Trento, I-38123 Trento, - - 2014
Blood flow in arterial systems can be described by the three-dimensional Navier-Stokes equations within a time-dependent spatial domain that accounts for the elasticity of the arterial walls. In this article, blood is treated as an incompressible Newtonian fluid that flows through compliant vessels of general cross section. A three-dimensional semi-implicit ...
Vigolo Daniele D Department of Mechanical and Aerospace Engineering, Princeton University, Princeton, NJ 08544, USA. - - 2014
The integration of Microbial Fuel Cells (MFCs) in a microfluidic geometry can significantly enhance the power density of these cells, which would have more active bacteria per unit volume. Moreover, microfluidic MFCs can be operated in a continuous mode as opposed to the traditional batch-fed mode. Here we investigate the ...
Shih Yu-Ju - - 2014
In this work, hemocompatibility of polyampholyte copolymers from the mixed charge copolymerization of the negatively charged 3-sulfopropyl methacrylate (SA) and positively charged [2-(Methacryloyloxy)ethyl] trimethylammonium (TMA) were studied. Charge-bias variation of the prepared poly(SA-co-TMA) copolymers can be controlled using the regulated SA and TMA monomer ratio via homogeneous free radical copolymerization. ...
Meehan Stephen S Department of Genetics, Stanford University School of Medicine, Stanford, CA, 94305, - - 2014
Nowadays, one can hardly imagine biology and medicine without flow cytometry to measure CD4 T cell counts in HIV, follow bone marrow transplant patients, characterize leukemias, etc. Similarly, without flow cytometry, there would be a bleak future for stem cell deployment, HIV drug development and full characterization of the cells ...
Kubo Yoshiyuki Y Department of Pharmaceutics, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, 2630, Sugitani, Toyama 930-0194, - - 2014
The elimination of spermine, the end product of cellular polyamine, from the retina to the blood across the blood-retinal barrier (BRB) was investigated. The in vivo microdialysis study revealed that the elimination of [(3)H]spermine from vitreous humor after vitreous bolus injection was in a biexponential manner. The rate constant for the ...
Amtul Zareen - - 2014
Abstract Currently, there is great interest in the assembly and function of cerebral endothelial, glial and neuronal cells that form the anatomical basis of the neurovascular unit (NVU) to maintain blood-brain barrier (BBB) and cerebral blood flow. Recent studies have provided considerable insight into the assembly of the components of ...
Kent M W MW Research Laboratory, Bonfils Blood Center, Denver, Colorado, USA; Department of Pediatrics, University of Colorado, Denver, Colorado, - - 2014
Microparticles (MPs) are submicron size cell fragments that are released from cells. We hypothesise that MPs increase during red blood cell (RBC) storage and are part of the pro-inflammatory activity, which accumulates in the RBC supernatant. RBC units were separated from whole blood of eight healthy donors: 5 U were split, ...
Prieto-García Alicia A Allergy Service, Hospital Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, Dr Esquerdo 46, Madrid 28007, Spain. Electronic address: - - 2014
Tetramer-forming tryptase (hTryptase-β) was recently discovered to have a prominent role in preventing the internal accumulation of life-threatening fibrin deposits and fibrin-platelet clots. The anticoagulant activity of hTryptase-β is an explanation for the presence of hemorrhagic disorders in some patients with anaphylaxis or mastocytosis. The fragments of hFibrinogen formed by ...
Beng Tan Swee - - 2014
This study aimed to evaluate the bioefficacy and blood feeding inhibition of mosquitoes under laboratory conditions using the WHO tunnel test method on unwashed and washed long-lasting insecticide impregnated net with extrinsic heat treatment of 30 degrees C followed by 80 degrees C on the same net during washing. PermaNet ...
Edner A A Departments of Clinical Sciences, Faculty of Veterinary Medicine and Animal Science, University of Agricultural Sciences, Uppsala, - - 2014
Static magnetic blankets are often claimed to induce increases in blood flow, reduce muscle tension and tenderness, and be beneficial in both prevention and treatment of musculoskeletal injuries in horses. However, there are no studies that confirm alleged beneficial effects of magnets on muscles of the back in healthy horses. ...
Hartwig Jan J Institut für Organische Chemie, Leibniz Universität Hannover, Schneiderberg 1B, 30167 Hannover, - - 2014
Continuous flow chemistry as a process intensification tool is well known. However, its ability to enable chemists to perform reactions which are not possible in batch is less well studied or understood. Here we present an example, where a new reactivity pattern and extended reaction scope has been achieved by ...
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