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Viallat A A Laboratoire Adhésion and Inflammation, Inserm U1067, CNRS UMR 7333, Aix-Marseille Université, Marseille, - - 2014
There is a number of publications on red blood cell deformability, that is, on the remarkable cell ability to change its shape in response to an external force and to pass through the narrowest blood capillaries and splenic sinuses. Cell deformability is postulated to be a major determinant of impaired ...
Prieto-García Alicia A Allergy Service, Hospital Universitario Gregorio Marañón, Instituto de Investigación Sanitaria Gregorio Marañón, Dr Esquerdo 46, Madrid 28007, Spain. Electronic address: - - 2014
Tetramer-forming tryptase (hTryptase-β) was recently discovered to have a prominent role in preventing the internal accumulation of life-threatening fibrin deposits and fibrin-platelet clots. The anticoagulant activity of hTryptase-β is an explanation for the presence of hemorrhagic disorders in some patients with anaphylaxis or mastocytosis. The fragments of hFibrinogen formed by ...
Fedosov Dmitry A DA Theoretical Soft Matter and Biophysics, Institute of Complex Systems and Institute for Advanced Simulation, Forschungszentrum Jülich, 52425 Jülich, Germany. - - 2014
The motion of red blood cells (RBCs) in microcirculation plays an important role in blood flow resistance and in the cell partitioning within a microvascular network. Different shapes and dynamics of RBCs in microvessels have been previously observed experimentally including the parachute and slipper shapes. We employ mesoscale hydrodynamic simulations ...
Zhang Ye - - 2014
While living systems have developed highly efficient ways to convert chemical energy (e.g., ATP hydrolysis) to mechanical motion (e.g., movement of muscle), it remains a challenge to build muscle-like biomimetic systems to gen-erate mechanical force directly from chemical reactions. Here we show that a continuous flow of reactant solution leads ...
Hebels Dennie G A J DG Department of Toxicogenomics, Maastricht University, Universiteitssingel 50, 6229 ER Maastricht, The - - 2014
In the context of environmental health research, biobank blood samples have recently been identified as suitable for high-throughput omics analyses enabling the identification of new biomarkers of exposure and disease. However, blood samples containing the anti-coagulant heparin could complicate transcriptomic analysis because heparin may inhibit RNA polymerase causing inefficient cRNA ...
Depoorter M M Cliniques Universitaires Saint-Luc, Brussels, - - 2014
Corelab automation needs increasingly more efficient hematology analyzers and algorithms to adequately detect abnormal samples. The aim of this study is to assess the effect of combining flags or to adjust their trigger level to identify positive samples for further detection within a smear. Five hundred and seventeen EDTA samples ...
de Grandmont M J MJ Héma-Québec, Operational Research, R&D, Quebec, QC, - - 2014
Many international standards state that red blood cell (RBC) products should be discarded if left out of controlled temperature storage for longer than 30 min to reduce the risk of bacterial growth and RBC loss of viability. This study aimed to verify whether repeated short-time exposures to room temperature (RT) influence ...
Zhu M F MF MOE Key Laboratory of Laser Life Science & Laboratory of Photonic Chinese Medicine, College of Biophotonics, South China Normal University, Guangzhou, P.R. - - 2014
Raman spectroscopy has been shown to have the potential for revealing oxygenated and spin ability of hemoglobin. In this study, confocal micro-Raman spectroscopy is developed to monitor the effect of sodium nitrite on oxyhemoglobin (HbO2 ) in whole blood. We observe that the band at 1,638 cm(-1) which is sensitive to ...
Trigo P P Center of Biotechnology in Reproduction (CEBIOR-BIOREN), La Frontera University, Temuco, - - 2014
The short-term storage of salmonid semen is a viable method for in vitro fertilisation. Previous studies have found that short-term storage affects sperm motility, compromising quality and fertilising capacity. However, the functional characteristics of the spermatozoa of O. mykiss during storage time and its relation to the spawning period are little ...
Basey-Fisher Toby H TH Department of Materials, Imperial College London, London, SW7 2AZ, - - 2014
The electric field component of the microwaves emanating from the dielectric resonator is able to penetrate the microfluidic channel, serum, and individual blood cells. Subsequently, it interacts with every hemoglobin molecule present within each red blood cell. On page 536 , Toby H. Basey-Fisher and team conclude that the dielectric ...
Rocha Silvia Faria da SF Unit Operation Laboratory, School of Chemistry and Food, Federal University of Rio Grande - FURG, Rio Grande, RS, Brazil. - - 2014
In this study was evaluated a preparation of vegetable paste with bovine blood in order to maximize the protein content using linear programming, and to analyze the product characteristics and quality of bovine blood enriched vegetable paste in a spouted bed. The drying experiments were performed by evaluating the effects ...
Nam Yun Sik YS Advanced Analysis Center, Korea Institute of Science and Technology, P.O. Box 131, Cheongryangri, Seoul, 130-650, - - 2014
A guidebook detailing the process of forensic investigation was written in 1440 A.C.E. It outlines the fundamentals and details of each element of criminal investigation during the era of the Chosun dynasty in Korea. Because this old guidebook was written in terms of personal experience rather than on scientific basis, ...
Denis-Robichaud J J Faculté de Médecine Vétérinaire, Université de Montréal, C.P. 5000, St-Hyacinthe, Quebec, J2S 7C6, - - 2014
The objectives of this study were (1) to determine the correlations between blood β-hydroxybutyrate (BHBA) and milk components [BHBA, acetone, fat, protein, and fat:protein (F:P) ratio], and (2) to establish optimal thresholds for milk components to predict hyperketonemia in dairy cows. Data on 163 cows from 37 herds were used ...
Chan Kasey Sze-Kei KS Research and Development, Australian Red Cross Blood Service, Melbourne, Victoria, - - 2014
Microparticles (MPs) are small phospholipid-containing vesicles that have procoagulant properties. MPs are thought to contribute to the hemostatic potential of plasma. This study investigated the effects of whole blood (WB) hold time and leukoreduction (LR) on the MP profile and hemostatic potential of fresh-frozen plasma (FFP). WB units (n = 12) from ...
Park Jong-Myeon - - 2014
Full automation with high purity for circulating tumor cell (CTC) isolation has been regarded as a key goal to make CTC analysis a "bench to bedside" technology. Here, we have developed a novel centrifugal microfluidic platform that can isolate the rare cells from a large volume of whole blood. To ...
Lelliott Patrick M - - 2014
Malaria treatments are becoming less effective due to the rapid spread of drug resistant parasites. Increased understanding of the host/parasite interaction is crucial in order to develop treatments that will be less prone to resistance. Parasite invasion of the red blood cell (RBC) is a critical aspect of the parasite ...
Atigui Moufida M Livestock and Wildlife Laboratory, Arid Lands Institute, 4119 Médenine, - - 2014
In order to evaluate milking ability in dromedary camels, 124 milk flow curves were registered during morning milking of 20 dairy Maghrebi dromedary camels. Animals were in lactations 1-8, were 6-19 years old and were 4-15 months of their current lactation. Milk flow curves were recorded using an electronic milk ...
Stoffel M M Climatic Change and Climate Impacts, Institute for Environmental Sciences, University of Geneva, Chemin de Drize 7, CH-1227 Carouge, Switzerland; Department of Earth Sciences, University of Geneva, Rue des Maraîchers 13, CH-1211 Geneva 4, Switzerland; Dendrolab.ch, Institute of Geological Sciences, University of Bern, Baltzerstrasse 1+3, CH-3012 Bern, Switzerland. Electronic address: - - 2014
This paper addresses the current knowledge on climate change impacts on mass movement activity in mountain environments by illustrating characteristic cases of debris flows, rock slope failures and landslides from the French, Italian, and Swiss Alps. It is expected that events are likely to occur less frequently during summer, whereas ...
McLaughlin Gregory G Department of Chemistry, University at Albany, State University of New York,, 1400 Washington Avenue, Albany, NY 12222, United - - 2014
The characterization of suspected blood stains is an important aspect of forensic science. In particular, determining the origin of a blood stain is a critical, yet overlooked, step in establishing its relevance to the crime. Currently, assays for determining human origin for blood are time consuming and destructive to the ...
Winter Kelly M KM Research and Development, Australian Red Cross Blood Service, Sydney, NSW, - - 2014
Over the past decade there has been a growth in the development of pathogen reduction technologies to protect the blood supply from emerging pathogens. This development has proven to be difficult for red blood cells (RBCs). However the S-303 system has been shown to effectively inactivate a broad spectrum of ...
Qin Jianbing - - 2014
The enumeration and characterization of circulating tumor cells (CTCs) in the blood of cancer patients is useful for cancer prognostic and treatment monitoring purposes. The number of CTCs present in patient blood is very low; thus, robust technologies have been developed to enumerate and characterize CTCs in patient blood samples. ...
Pan Qingjun Q a Institute of Nephrology Affiliated Hospital of Guangdong Medical College , Zhanjiang , - - 2014
To evaluate the effect of four widely used red blood cell lysing solutions on counting and measurement of activation marker of peripheral basophils in normals and SLE patients by flow cytometry. Our results showed that the light scatter properties including FS and SS value of leukocytes in whole blood were ...
Karabacak Nezihi Murat NM 1] Department of Surgery and Center for Engineering in Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA. - - 2014
The ability to isolate and analyze rare circulating tumor cells (CTCs) has the potential to further our understanding of cancer metastasis and enhance the care of cancer patients. In this protocol, we describe the procedure for isolating rare CTCs from blood samples by using tumor antigen-independent microfluidic CTC-iChip technology. The ...
van Beers Eduard J EJ Hematology Branch, Electron Microscopy Core Facility and Flow Cytometry Core Facility, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, MD, - - 2014
In preclinical and early phase pharmacologic trials in sickle cell disease, the percentage of sickled erythrocytes after deoxygenation, an ex vivo functional sickling assay, has been used as a measure of a patient's disease outcome. We developed a new sickle imaging flow cytometry assay (SIFCA) and investigated its application. To ...
Herbert Corentin C National Center for Atmospheric Research, P.O. Box 3000, Boulder, Colorado 80307, - - 2014
Equilibrium statistical mechanics tools have been developed to obtain indications about the natural tendencies of nonlinear energy transfers in two-dimensional and quasi-two-dimensional flows like rotating and stratified flows in geostrophic balance. In this article we consider a simple model of such flows with a nontrivial vertical structure, namely, two-layer quasigeostrophic ...
Suryadi Alexandre A Linné FLOW Centre, KTH Mechanics, SE-100 44 Stockholm, - - 2014
For pressure-driven turbulent channel flows undergoing spanwise system rotation, it has been observed that the absolute vorticity, i.e., the sum of the averaged spanwise flow vorticity and system rotation, tends to zero in the central region of the channel. This observation has so far eluded a convincing theoretical explanation, despite ...
Zhao Yurong Y Department of Mechanics and Engineering Science, College of Engineering, Peking University, Beijing 100871, People's Republic of - - 2014
Transition from a Taylor-Couette turbulent flow to a completely two-dimensional axisymmetric turbulent state is realized numerically by increasing gradually the strength of the azimuthal magnetic field produced by electric current flowing through the axial rod. With the increase of the Hartmann number, the Taylor-vortex-like structures shrink, move closer to the ...
Papoutsis Ioannis - - 2014
The stability of drugs in biological specimens is a major concern during the evaluation of the toxicological results. The stability of morphine, codeine, and 6-acetyl-morphine in blood was studied after different sampling conditions: (i) in glass, polypropylene or polystyrene tubes, (ii) with addition of dipotassium ethylene diamine tetraacetic acid (K2EDTA) ...
Connes Philippe P UMR Inserm 1134, Université des Antilles et de la Guyane, Pointe-à-Pitre, Guadeloupe, France; Institut Universitaire de France, Paris, France; Laboratory of Excellence GR-Ex (The red cell: from genesis to death), PRES Sorbonne Paris Cité, Paris, France; Laboratoire ACTES (EA 3596), Département de Physiologie, Université des Antilles et de la Guyane, Pointe-à-Pitre, Guadeloupe, - - 2014
Although pulmonary hypertension, leg ulcers, priapism, stroke and glomerulopathy in sickle cell anaemia (SCA) result from the adverse effects of chronic haemolysis on vascular function (haemolytic phenotype), osteoneocrosis, acute chest syndrome and painful vaso-occlusive crises are caused by abnormal vascular cell adhesion and increased blood viscosity (viscosity-vaso-occlusion phenotype). However, this ...
Kuruvilla Denison J DJ Department of Pharmaceutics and Translational Therapeutics, College of Pharmacy, University of Iowa, Iowa City, - - 2014
The quality of transfused red blood cells (RBCs) to treat anemia depends on its potential for oxygen delivery, governed by two properties: 1) initial posttransfusion recovery and 2) life span of initially surviving RBCs. The latter property is poorly evaluated by the traditional mean potential life span (MPL) or mean ...
Graham Richard S RS School of Mathematical Sciences, University of Nottingham, Nottingham NG7 2RD, UK. - - 2014
Flow profoundly influences the crystallisation kinetics and morphology of polymeric materials. By distorting the configuration of polymer chains, flow breaks down the kinetic barriers to crystallisation and directs the resulting crystallisation. This flow-induced crystallisation (FIC) in polymers is a fascinating, externally driven, non-equilibrium phase transition, which is controlled by kinetics. ...
Santacruz Stalin S Division of Analytical Chemistry, Department of Chemistry, Centre for Chemistry and Chemical Engineering, Faculty of Engineering LTH, Lund University, P.O. Box 124, SE-221 00 Lund, Sweden. Electronic address: - - 2014
The properties of a paper sheet depend on the absorption together with the physico-chemical properties of additives used in the paper processing. The effect of ionic strength and degree of substitution of cationic potato starch on the elution pattern of asymmetrical flow field-flow fractionation was analysed. The effect of starch ...
Wuest Diane M DM Department of Chemical and Biomolecular Engineering and Delaware Biotechnology Institute, University of Delaware, 15 Innovation Way, Newark, DE 19711, - - 2014
Intravenous immunoglobulin (IVIG) contains anti-amyloid-β antibodies as well as antibodies providing immunomodulatory effects that may modify chronic inflammation in Alzheimer's disease. Answers to important questions about IVIG transport into the central nervous system and assessing any impact amyloid-β has on this transport can be provided by in vitro models of ...
Hosono Takahiro T Priority Organization for Innovation and Excellence, Kumamoto University, 2-39-1 Kurokami, Kumamoto 860-8555, Japan. Electronic address: - - 2014
We present an approach for determining the major anaerobic bacterial processes in aquifers, using the combined stable isotope ratios of major elements (C, N, and S) as net recorders of the biogeochemical reactions. The Kumamoto groundwater is constituted of two major flow systems, A-A' and B-B', within 10(3) km-scale area. Previous ...
Yu Zeta Tak For ZT Integrated Biosystems and Biomechanics Laboratory, University of Michigan, Ann Arbor, Michigan, USA; Department of Mechanical Engineering, University of Michigan, Ann Arbor, Michigan, - - 2014
Blood plays an important role in homeostatic regulation with each of its cellular components having important therapeutic and diagnostic uses. Therefore, separation and sorting of blood cells hasa been of a great interest to clinicians and researchers. However, while conventional methods of processing blood have been successful in generating relatively ...
Schilcher Gernot G Clinical Division of Nephrology, Department of Internal Medicine, Medical University of Graz, Graz, - - 2014
Due to its reported antimicrobial effects, hypertonic citrate (46.7%) is a widely used catheter lock solution, but following instillation, citrate inevitably spills into the systemic circulation. This process is mainly driven by hydraulic effects during instillation and density differences between blood and lock solution. Hence, in haemodialysis catheters, intra-luminal citrate ...
Gross Elad - - 2014
Analysis of catalytic organic transformations in flow reactors and detection of short-lived intermediates under reaction conditions are essential for the optimization and understanding of these complex reactions. In this study, spectral mapping of a multi-step catalytic reaction in a flow micro-reactor was performed with a spatial resolution of 15µm, employing ...
Schroedl Wieland W Institute of Bacteriology and Mycology, Veterinary Faculty, University of Leipzig, Germany, An den Tierkliniken 29, D-04103, Leipzig, - - 2014
Little is known about the bovine intestinal microbiota influence on systemic innate immune responses. The objective of the present study was to determine relationships between acute phase proteins in blood serum of cows, [C-reactive protein (CRP), LPS-binding protein (LBP) and haptoglobin (Hp)] and the faecal microbiota. Fifty-two healthy cows (2-8 ...
Roback John D JD Center for Transfusion and Cellular Therapies, Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, GA. Electronic address: - - 2014
Population-based investigations suggest that red blood cells (RBCs) are therapeutically effective when collected, processed, and stored for up to 42 days under validated conditions before transfusion. However, some retrospective clinical studies have shown worse patient outcomes when transfused RBCs have been stored for the longest times. Furthermore, studies of RBC ...
Yadav Maya M Department of Botany, Faculty of Science, Banaras Hindu University, Varanasi 221005, - - 2014
Biodegradation of chlorpyrifos (CP) by Pseudomonas (Iso 1) sp. was investigated in batch as well as continuous bioreactors packed with polyurethane foam pieces. The optimum process parameters for the maximum removal of CP, determined through batch experiments, were found to be: inoculum level, 300×10(6)CfumL(-1); CP concentration, 500mgL(-1); pH 7.5; temperature, ...
Mosher Ruby A RA Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan, KS - - 2014
Objective-To determine the effects of protease inhibitors and holding times and temperatures before processing on the stability of substance P in bovine blood samples. Samples-Blood samples obtained from a healthy 6-month-old calf. Procedures-Blood samples were dispensed into tubes containing exogenous substance P and 1 of 6 degradative enzyme inhibitor treatments: ...
Devanesan Sandhanasamy S King Saud University, College of Science, Physics and Astronomy Department, Riyadh 11451, Saudi ArabiadBharathiar University, Research and Development Centre, Coimbatore 641046, - - 2014
ABSTRACT. Thalassemia (Thal), sickle cell anemia, and iron deficiency anemia (IDA) are the most common blood disorders in many parts of the world, particularly in developing countries like India and Bangladesh. The well-established diagnostic procedure for them is the complete blood count (CBC); however, there is substantial confusion in discrimination ...
Nakada Kojin K Department of Molecular and Applied Bioscience, Graduate School of Biosphere Sciences, Hiroshima - - 2014
Peripheral blood cells from ayu, Plecoglossus altivelis altivelis, were separated using a density gradient. Blood cells were then smeared using Shandon Cytospin and subjected to cytochemical staining. Blood cells were categorized based on morphological and cytochemical characteristics, and the density fractionation range and nuclear area/cell area ratio were observed. Lymphocytes ...
Shokrzadeh M M Pharmaceutical Sciences Research Center, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, - - 2014
Hesperidin (Hes), a natural bioflavonoid, is abundant in citrus fruit and has been reported to exert a wide range of pharmacological effects. Diazinon (DZN) can be mutagenic, or capable of inducing genetic damage, in human blood cells. The protective effect of Hes against DZN-induced micronucleus formation, an index of DNA ...
Michelle W M WM Center for Biomedical Research, Population Council, 1230 York Ave, NY, New York 10065 Revision - - 2014
Two important events that occur during mammalian spermatogenesis are the release of elongated spermatids at late stage VIII of the seminiferous epithelial cycle and the restructuring of the blood-testis barrier during stages VIII-XI. Still, it is not completely understood how these cellular events are accomplished within the seminiferous epithelium. In ...
Shen Hai-Yan HY Key Laboratory of Biology and Genetic Resources of Tropical Crops, Ministry of Agriculture, Institute of Tropical Bioscience and Biotechnology, Chinese Academy of Tropical Agricultural Sciences, 571101, Haikou, PR China; Horticultural and Garden College, Hainan University, Haikou 570228, - - 2014
Six new steroidal saponins, cambodianosides A-F (1-6), together with seven known ones, were isolated from the dragon's blood of Dracaena cambodiana. The structures of 1-6 were elucidated on the basis of detailed spectroscopic analysis, including 1D and 2D NMR techniques and chemical methods. The cytotoxicities of all the isolated compounds ...
Wang Qi Q Key Laboratory of Drug Targeting and Novel Drug Delivery Systems, Ministry of Education, West China School of Pharmacy, Sichuan University, Chengdu 610041, People's Republic of China. State Key Laboratory of Oncogenes and Related Genes, Shanghai Cancer Institute, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200032, People's Republic of - - 2014
Biodegradable chitosan-graft-polylactide (PLA-CS) copolymers were prepared by the grafting of a poly(L-lactide) (PLLA) or poly(D-lactide) (PDLA) precursor to the backbone of chitosan using 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC ⋅ HCl) and N-hydroxysuccinimide (NHS) as a coupling agent. The blood and cell compatibility of the graft copolymers were investigated in comparison to PLLA and ...
Naziruddin B B Annette C. and Harold C. Simmons Transplant Institute, Baylor University Medical Center at Dallas, Dallas, - - 2014
A nonspecific inflammatory and thrombotic reaction termed instant blood-mediated inflammatory reaction (IBMIR) has been reported when allogenic or xenogenic islets come into contact with blood. This reaction is known to cause significant loss of transplanted islets. We hypothesized that IBMIR occurs in patients undergoing total pancreatectomy followed by autologous islet ...
Sagaidachnyi A A - - 2014
It is well established that skin temperature oscillations in fingertips coexist with blood flow oscillations and there is a certain correlation between them. At the same time, the reasons for differences in waveform and the delay between the blood flow and temperature oscillations are far from being fully understood. In ...
Lu Jiangang J State Key Laboratory of Industrial Control Technology, Department of Control Science and Engineering, Zhejiang University, Hangzhou 310027, - - 2014
In this paper, a miniature methanol fuel processor and its controller design is introduced for onboard hydrogen production. The hydrogen is generated via autothermal reforming of methanol. The control scheme consists of a hydrogen flow rate controller and a reforming temperature controller. To deal with uncertain system dynamics and external ...
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