Intraoperative graft flow responses in 15 patients who underwent coronary artery bypass grafting (CABG) were studied systematically. The mean blood flow for 13 left anterior descending (LAD) coronary artery grafts was 64 +/- 20 ml/min and for 12 right coronary artery (RCA) grafts was 53 +/- 13 ml/min. Of these, ...

The hemodynamics of extra-anatomic bypass were studied with the use of right to left iliac artery bypass grafts. An arteriovenous fistula on the recipient side was used to increase the flow through the graft. Flow measurements in this model under normotensive conditions showed proportionate increases in the suprarenal aortic blood ...

The Gould Statham Blood Flowmeter Model SP 2204 has been used to assess microanastomosis in 25 superficial femoral arteries of rabbits. When a pulsatile wave form has been achieved this correlates with a satisfactory anastomosis and vice versa. The digital read out of estimated volume flow past the anastomosis made ...

Fistula puncture site blood loss during and after hemodialysis was measured in 12 patients with end-stage renal disease. It was found to be 0.74 +/- 0.32 ml per dialysis and 115.4 +/- 49.9 ml per year in patients with Cimino A-V fistulas. Puncture site blood leak in patients with heterologous ...

The microvascular sleeve anastomosis, where one vessel is inserted into the other, was compared with the conventional end to end anastomosis. In an experimental study in rat femoral arteries 42 anastomoses of each kind were examined. Operating time, patency rates, flow rates and strength of the anastomoses were recorded at ...

Intra-operative measurement of leg blood flow is useful not only for the detection of a technical fault. It has also proved to be a sensitive method to disclose hypovolaemia. Thus, if the blood volume is not restored, the peripheral vasoconstrictor tone remains elevated. In such a state, the basal leg ...

The long-term effectiveness of a retrograde coronary venous bypass graft (CVBG) to an ischemic left ventricle was evaluated in 18 dogs. A saphenous vein was interposed between the aorta and left anterior descending (LAD) vein. The LAD vein was ligated cephalad to the CVBG to prevent an arteriovenous fistula. The ...

A videodensitometric method for estimating relative flow was employed in a patient with a bovine arteriovenous fistula. Analogous arteriovenous communications of different sizes were created in two dogs for comparison. Local and general hemodynamic parameters were measured. The videodensitometric method proved to be highly accurate compared to electromagnetic flow readings ...

Blood flow (133Xe clearance) and plasma exudation ([133I]HSA) have been measured in the immune lymphocyte transfer (ILT) reaction and skin grafts in rabbits. Injection of sensitised lymphocytes produced a dose-related increase in plasma exudation and blood flow at 48 hr, reached a maximum at day 3 and faded from day ...

On hundred forty six (146) vascular graft insertions have been examined to determine the best exposure media, the mode of exposure, and the time of exposure required to change the TP of knitted dacron fabric. Whole blood, plasma, albumin, and Ringer's lactate (as control) were the media used. The mode ...

The technique presented in this paper is based on the authors' previous observations in which they found that artificial decrease of blood flow to a portion of the heart muscle leads to an immediate and proportional drop in the regional myocardial temperature. It appeared to the authors as a logical ...

We have measured blood flows in 155 limbs with chronic arterial occlusive disease after revascularization procedures. Blood flows were recorded during standard electromagnetic flowmeter techniques. Base line flows after maximal vasodilatation with papaverine were recorded. The most important measurement to determine immediate results was the percentage increase of the basal ...

Popliteal artery injuries are followed, in many cases, by amputation of the leg. Results after re-construction depend on the time of ischemia. In this experimental work 12 dogs with injury of the popliteal artery had a direct end to end anastomosis or an anastomosis using saphenous vein graft. Blood flow ...

Histologic changes in canine autogenous femoral veins were studied after interposition into the femoral artery. After a 50 per cent reduction of distal blood flow, marked fibrosis of the intima, causing narrowing of the intima and focal destruction of the internal elastic membrane and media, were found in the vein ...

The prognostic value of Doppler-derived ankle systolic pressure indices for predicting the patency of vein bypass grafts in the lower extremity was analyzed in 126 vein bypass grafts performed for limb salvage. Early or late graft failure was not found to correlate with the preoperative ankle systolic pressure index (ASPI). ...

A rare case of hypertrophic osteoarthropathy (HO) limited to one lower extremity is described in a male with a history of familial polyposis coli and bilateral aortofemoral grafts. The precise etiology remains unknown. Radiography depicted the HO, but 99m Tc-methylene diphosphonate imaging showed more extensive involvement. An intra-aortic injection of ...

Few investigations have been made to date on the in vivo behavior of blood vessel grafts. An experimental model is described which permits continuous monitoring of grafted arteries both by gross examination and by in vivo microscopy. Allografts and autografts of the central ear arteries of rabbits, 0.5 mm in ...

Forty-six patients with ulnar artery thrombosis were evaluated. A comparison of the results was made between those patients who were treated by sympathectomy and those in whom we attempted to reestablish the blood flow. A reverse vein graft was often used in the latter group. Based on the results of ...

After auxiliary liver transplantation in the rat, partial liver grafts (30% of the liver) were perfused with mesentericosplenic venous blood. This means a decrease in the total liver blood flow by approximately 34%. Recipient livers retained their arterial and pancreaticoduodenal inflow. Surgical interventions were carried out on the recipient's liver ...

The immediate effect of lumbar sympathectomy on arterial blood flow was studied in 51 patients with peripheral arterial disease by means of electromagnetic flowmetry. Concomitant arterial reconstruction was performed in 37 cases. The measurement was made on the reconstructed segment or on the bypass graft, and on the femoral artery ...

In 1973 we reported significantly superior survival of kidneys transplanted to blood group O recipients compared with recipients of those from blood groups A, B, and AB taken together. In this extended series, the difference between these categories was less prominent and no longer significant. In the present study, blood ...

The proper biologic evaluation of biomaterials for blood-contacting applications must include considerations of hemorheologic parameters, species-related differences, and damages to the reticuloendothelial system. Although there are no materials currently available that are completely blood compatible, several smooth-surfaced polymers are quite tolerable in the physiological environment. These include chemically grafted polyacrylamide ...

With use of the Doppler ultrasonic flowmeter catheter, phasic aortocoronary bypass graft blood velocity was measured in 16 conscious subjects during ventricular arrhythmias. Ventricular extrasystoles reduced peak systolic and diastolic graft blood velocities by 20 to 80 percent, generally in relation to their respective coupling intervals. When extrasystoles appeared in ...

Vertebral artery blood flow was studied by a Doppler ultrasound technique in two patients with the subclavian steal syndrome. The Doppler probe was positioned in the region of the Chassaignac tubercle. The direction of vertebral artery flow corresponded with the angiographic flow direction preoperatively. Postoperatively, the technique was used to ...

With the use of a Doppler flowmeter catheter, phasic instantaneous aortocoronary saphenous vein bypass graft blood velocity was continuously measured during the inhalation of amyl nitrite in 20 closed-chest conscious subjects. Administration of amyl nitrite augmented peak diastolic and systolic graft blood velocity within 10 seconds and maximal blood velocities ...

Local flow characteristics were studied in 21 patients with end-to-side cephalic vein to radial artery fistulas, constructed in the wrist for chronic hemodialysis. Intraoperative electromagnetic flow studies indicated a mean fistula flow of 242+/-72 milliliters per minute. Approximately two-thirds of the total fistula flow was derived from antegrade flow in ...

Small fragments of kidney tissue were grafted into the right lung (Xenopus laevis) and the left lung was subsequently removed. This stimulated compensatory hyperplasia (increased mitotic rate) in alveolar tissue of the right lung and in the kidney graft. This suggests that the stimulus to compensatory hyperplasia is location-specific rather ...

The distensibility of arterial wall is an important factor in the haemodynamics of pulsatile blood-flow. Autogenous-vein grafts have a dynamic response to the arterial pressure pulse (compliance) which approaches that of normal arterial wall, whereas synthetic prostheses are generally incompliant, or become so shortly after implantation. Although synthetic grafts have ...

Leakage in anastomoses below the peritoneal reflection after resection of the upper rectum and lower sigmoid colon has been studied in an experimental model in the dog. With blood alone or with blood and E. coli in the pelvis about the anastomosis, there was no significant increase in the frequency ...

Skin allografts and xenografts are routinely used as dressings to control infection, pain and fluid loss from the burn wound. The procedure for preparing and storing grafts will be reviewed and suggested indications for use will be considered. A method for preparing porcine xenograft will be discussed in some detail. ...

A new microporous, expanded polytetrafluoroethylene arterial prosthesis was evaluated in dogs. The material appears to produce an adequate prosthesis for aortopulmonary anastomosis in animals and can conduct a high rate of blood flow. The graft has been used in 3 patients with pulmonary atresia aged 2 days, 2 months, and ...

Thirteen femoral vein autografts were placed into the corresponding ipsilateral femoral arteries of 8 mongrel dogs. Cuff-type Doppler (ultrasonic) flowmeters were placed around six of the grafts. None of the vessels thrombosed. Blood flow velocities were measured in all vessels up until the time of sacrifice (mean 95 +/- 5 ...

Post-reconstructive graft blood flow (basal flow') was measured by means of an electromagnetic flowmeter in 72 consecutive femoropopliteal reversed saphenous vein grafts performed for occlusive atherosclerosis causing leg ischaemia. In the last 48 operations, post-reconstructive pre- and post-graft intra-arterial pressures were recorded, and graft blood flow after papavarine-induced vasodilation ('maximal ...

Blood flow in aortocoronary saphenous vein grafts was studied in response to intragraft injection of sodium nitroprusside and papaverine hydrochloride. Following injection of 50 mug of sodium nitroprusside, mean graft flow increased from 40.1 +/- 4.5 to 81.3 +/- 8.5 ml per minute. Administration of 30 mg of papaverine hydrochloride ...

Phasic blood flow recorded in five unobstructed dog aortocoronary bypass grafts to the left coronary artery was similar to that of normal coronary arteries, with a high diastolic-to-systolic flow ratio which averaged 2.7 +/- 0.4. With an average of 52 +/- 7% and 72 +/- 6% stenosis in the coronary ...

The blood lost through the suture line holes of vessels closed with braided polyester sutures is compared with that lost when a monofilament polypropylene suture is employed. In a retrospective analysis of blood replacement during saphenous vein aortorenal bypasses, twice as much blood replacement was required when the braided polyester ...

To study aortocoronary vein graft flow, hemodynamic measurements were made in 17 patients with 22 grafts while on cardiopulmonary bypass during ventricular fibrillation and sinus rhythm and 15 minutes after termination of cardiopulmonary bypass. When compared with graft flow to the stable working heart, flow to the nonworking heart in ...

Myocardial blood flow was measured by the 133Xe clearance technique in 21 patients 6 to 31 months after saphenous vein grafting for coronary arterial disease. Preoperative measurements were made in 16. All patients had improved symptomatically, and 20 had returned to work. Thirty of 39 grafts were entered and selective ...

The effect of augmented and reduced blood flow rates through autogenous vein grafts (AVG) on the histological characteristics of veins used for arterial substitutes was studied in 22 dogs. In each animal autogenous jugular veins were implanted as conduits to replace excised segments of both iliac arteries. In one group ...

Blood flow and patency rates obtained by lingual to basilar artery anastomosis were compared with those obtained by saphenous vein bypass graft from the carotid to the basilar artey in two groups of ten dogs. Flow was measured by an electromagnetic technique while blood pressure and blood gases were monitored. ...

An anatomical study shows that the vascular junctions are always very well rounded in accordance with the direction of the blood flow. When performing an anastomosis, the further one departs from this configuration, which we can define as perfect, the more flow disturbances are likely to arise. This may jeopardize ...

Adult, embryonic, and tumor tissues were grafted to the chorioallantoic membrane of the chick embryo to determine whether blood vessels originally within implants were reused in the establishment of a new blood supply. Grafts were examined daily by in vivo stereomicroscopy and in histologic sections. Colloidal carbon injections into the ...

Previous studies have shown that a single transfusion with whole blood from the intended marrow donor 10 days before 1,200 R of total body irradiation (TBI) and marrow grafting can immunize a dog and lead to rejection of the subsequent marrow graft. The present study explored the effect of time ...

A case of massive shotgun injury to the left thigh and hip is reported. The patient received 116 units of blood, and a femoro-subscrotal-femoral vein graft was employed to save the left leg. A Teflon wool blood transfusion filter, used from the beginning of therapy, was believed to have been ...

A quantitative preoperative coronary angiographic index was defined in 148 patients undergoing coronary revascularization. Each diseased vessel was scored 0-3, for both diameter and quality of run-off. The sum of the scores for diameter and run-off constituted the numerical index for the diseased vessel. Correlations between the index and graft ...

To determine the blood flow in healthy femoral arteries electromagnetic measurements were made on common femoral, superficial femoral and profunda femoris artery in 20 patients during operation for varicose veins. The values obtained were 239 ml/min, 134 ml/min, and 104 ml/min respectively. These registrations were compared with those achieved during ...

Blood flow through aorta-to-coronary artery bypass grafts has been measured selectively in 16 patients at or within 6 wk after operation. Inert gas desaturation curves were obtained from coronary venous blood samples after a 7-15 min infusion of dissolved H(2) directly into the graft. Samples were analyzed chromatographically and curves ...

Human skin grafted upon the chorio-allantoic membrane of chick embryos adheres and becomes nourished for as long as 10 days. Occasionally regrafts upon a second egg have succeeded and thus prolonged the vitality of the graft to 14 days. In successful experiments the epithelium of the chorio-allantois fuses with that ...

The B blood group locus in chickens is shown to be associated with the graft-against-host reaction in chick embryos.

Segments of abdominal aorta in 25 dogs were replaced by knitted Dacron prostheses in studies concerned with limiting the blood loss which ordinarily occurs through the walls of porous prostheses when circulation is reestablished after the graft is inserted. Dacron prostheses which had been coated with Gelfoam permitted significant blood ...