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Durnford A A Clinical Neurosciences, Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK, - - 2015
Rapid and effective clearance of cell-free haemoglobin after subarachnoid haemorrhage (SAH) is important to prevent vasospasm and neurotoxicity and improve long-term outcome. Haemoglobin is avidly bound by haptoglobin, and the complex is cleared by CD163 expressed on the membrane surface of macrophages. We studied the kinetics of haemoglobin and haptoglobin ...
Mogicato G G Unité d'Anatomie - Imagerie - Embryologie, Université de Toulouse, INP, ENVT, F-31076, Toulouse, France; Institut National de la Santé et de la Recherche Médicale (INSERM), Imagerie Cérébrale et Handicaps Neurologiques UMR 825, CHU Purpan, F-31024, Toulouse, - - 2014
Liver anatomy, particularly its vascularization, has been investigated in many studies in dogs. Knowledge of blood flow from the main tributaries of the portal vein (PV) is necessary to explain the preferential sites of secondary lesions within the liver based on the site of the initial malignant lesion. How these ...
Gester Kathrin K Department of Cardiovascular Engineering, Institute of Applied Medical Engineering, Helmholtz Institute, RWTH Aachen University, Aachen, - - 2014
Even though the separation of blood into erythrocyte-rich and erythrocyte-poor areas is well known in physiological setups such as small vessels, it has recently come into focus in small gaps in cardiovascular applications. Studies show that separation effects occur, for example, in gaps in hydrodynamic bearings, where they can have ...
Cevheri Necmettin - - 2014
Colloidal particles suspended in aqueous electrolyte solutions flowing through microchannels are subject to lift forces that repel the particles from the wall due to the voltage and pressure gradients commonly used to drive flows in microfluidic devices. There are very few studies that have considered particles subject to both an ...
Hårdstedt Maria M Department of Immunology, Genetics and Pathology, Clinical Immunology, The Rudbeck Laboratory, Uppsala University , Uppsala , - - 2014
Abstract Aims. Interaction between blood and bio-surfaces is important in many medical fields. With the aim of studying blood-mediated reactions to cellular transplants, we developed a whole-blood model for incubation of small volumes for up to 48 h. Methods. Heparinized polyvinyl chloride tubing was cut in suitable lengths and sealed ...
Da Luz Luis - - 2014
IntroductionThe understanding of coagulopathies in trauma has increased interest in thromboelastography (TEG®) and thromboelastometry (ROTEM®), which promptly evaluate the entire clotting process and may guide blood product therapy. Our objective was to review the evidence for their role in diagnosing early coagulopathies, guiding blood transfusion and reducing mortality in injured ...
Georgiou Marios M Director of Nursing, American Medical Center Cyprus; Cyprus Resuscitation - - 2014
High quality chest compressions is the most significant factor related to improved short-term and long-term outcome in cardiac arrest. However, considerable controversy exists over the mechanisms involved in driving blood flow. The aim of this systematic review is to elucidate major mechanisms involved in effective compression-mediated blood flow during adult ...
Sá Michel Pompeu Barros Oliveira MP Division of Cardiovascular Surgery of Pronto Socorro Cardiológico de Pernambuco, PROCAPE, Recife, Brazil University of Pernambuco, UPE, Recife, Brazil Nucleus of Postgraduate and Research in Health Sciences of Faculty of Medical Sciences and Biological Sciences Institute (FCM/ICB), Recife, Brazil - - 2014
Many surgeons are concerned about the flow capacity of a skeletonized internal thoracic artery (ITA) in comparison with a pedicled ITA used during coronary artery bypass graft (CABG). This work aims to summarize the evidence comparing the flow capacity of a skeletonized versus pedicled ITA during CABG. We performed systematic ...
Tantanate C C Department of Clinical Pathology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, - - 2014
Presence of peripheral blood nucleated red blood cell (NRBC) is associated with pathological conditions and leads to the overestimation of white blood cell count in automated haematology analysers (HA). The authors evaluated NRBC enumeration by a new HA Sysmex XN (XN) to demonstrate the precision and comparability to manual count ...
Knight R R University Hospital Birmingham, Birmingham, UK - - 2014
Caffeine is one of the most commonly consumed pharmacologically active ingredients in the Western world. It is postulated to cause peripheral vasoconstriction and decreased digital blood flow. As a result, many hand surgeons forbid caffeine consumption post-operatively by patients undergoing replantation surgery for fear of compromising healing. We hypothesized that ...
Repsold Lisa - - 2014
Novel, in silico-designed anticancer compounds were synthesized in our laboratory namely, 2-ethyl-3-O-sulphamoyl-estra-1,3,5(10),15-tetraen-17-ol (ESE-15-ol) and 2-ethyl-3-O-sulphamoyl-estra-1,3,5(10)16-tetraene (ESE-16). These compounds were designed to have improved bioavailability when compared to their source compound, 2-methoxyestradiol. This theoretically would be due to their increased binding affinity to carbonic anhydrase II, present in erythrocytes. Since the ...
Bachok Mohd Faez MF Department of Nutrition and Dietetics, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, 43400 Serdang, Selangor, Malaysia. - - 2014
Ulam refers to a group of traditional Malaysian plants commonly consumed as a part of a meal, either in the raw form or after a short blanching process. Many types of ulam are thought to possess blood glucose-lowering properties, but relatively little is known on the effectiveness of ulam in ...
Bamford R F - - 2014
This study describes how a vascular centre rationalised their blood transfusion policy. A multidisciplinary panel reviewed data for blood transfusion protocols and implemented improvements that were analysed. The number of units cross-matched fell from 272 to 183 over a six month period. Unused blood reduced from 80% to 61%. The ...
Nieuwenhuis Lotte L LL Department of Obstetrics and Gynaecology, VU Medical Center, Amsterdam, The - - 2014
To evaluate the interobserver agreement and discriminating value of three-dimensional power Doppler ultrasound (3D PDUS) in patients with fibroids. An observational prospective cohort study in 19 patients with fibroids. 3D PDUS was performed by one examiner and evaluated by three independent examiners in order to evaluate various vascular parameters: vascular ...
McCloskey Laura J LJ Jefferson University Hospitals, Philadelphia, - - 2014
Non-cellulose dried matrix spotting (DMS) cards are an alternative to filter paper (FP) for bloodspots. We compared the interpatient distributions of bloodspot areas between DMS and FP for a fixed volume of application of whole blood, and examined correlations of areas with hematocrit. EDTA-whole blood adult patient samples (n=49; 25 ...
Denniff Philip - - 2014
Volumetric Absorbtive Micro Sampling is a novel approach to obtaining a dried blood sample for quantitative bioanalysis that overcomes the area bias and sample homogeneity issues associated with conventional DBS when a sub-punch is taken from the sample. The VAMS sampler absorbs a fixed volume of blood (~10 µL) in ...
Peuke Andreas D AD ADP International Plant Science Consulting, Talstraße 8, D-79194 Gundelfingen, Germany; Institute for Landscape Biogeochemistry, Leibniz-Zentrum für Agrarlandschaftsforschung (ZALF) e.V., Eberswalderstr. 84, 15374 Müncheberg, - - 2014
Anoxic conditions should hamper the transport of sugar in the phloem, since this is an active process. The canopy is a carbohydrate source and the roots are carbohydrate sinks. By fumigating the shoot with N2 or flooding the rhizosphere, anoxic conditions in the source or sink, respectively, were induced. Volume ...
Ng Wl W Department of Anaesthesia, Auckland City Hospital, Auckland, New - - 2014
We investigated the accuracy of i-STAT(®) (Abbott Point of Care Inc., Princeton, NJ, USA) haemoglobin (Hb) measurement in surgical patients with an estimated blood loss of ≥25% of total blood volume. Blood tests for i-STAT(®) Hb, laboratory Hb (Sysmex XE-2100(™), Sysmex Corporation, Kobe, Japan) and total plasma proteins were obtained ...
Agrawal Amit A Blood Bank-Fortis Escorts Hospital, Okhla, New Delhi, - - 2014
The study was undertaken with the objective to provide data on the ABO and Rh(D) blood group distribution and gene frequency across India. A total of 10,000 healthy blood donors donating in blood banks situated in five different geographical regions of the country (North, South, East and Center) were included ...
Bishop Cecily V CV Division of Reproductive & Developmental Sciences, Oregon National Primate Research Center, Beaverton, OR, - - 2014
The objective of the current study was to determine changes to vascular parameters of nonhuman primate dominant ovarian structures by dynamic contrast-enhanced ultrasound (DCE-US). Dynamic contrast-enhanced ultrasound with intravenous microbubble infusion was performed on the rhesus macaque ovary bearing the pre-ovulatory follicle and corpus luteum (CL) sequentially during the natural ...
Schade Henning H Department of Medicine, Medical University of South Carolina, Charleston, South - - 2014
Compared with growth factor (G) alone, the combination of G with plerixafor (G + P) increases peripheral blood CD34+ count (PB-CD34+) and improves CD34+ collection yield (yCD34+) in multiple myeloma and lymphoma patients undergoing autologous hematopoietic progenitor cell (AHPC) mobilization. It is unknown whether the improved yCD34+ with G + P results entirely from ...
Benedictus Marije R MR Alzheimer Center & Department of Neurology, Neuroscience Campus Amsterdam, VU University Medical Center, Amsterdam, the Netherlands. Electronic address: - - 2014
To better understand whether decreased cerebral blood flow (CBF) in patients with Alzheimer's disease (AD) reflects neurodegeneration or cerebral small vessel disease, we investigated the associations of normalized brain volume (NBV) and white matter hyperintensity (WMH) volume with CBF. We included 129 patients with AD (66 ± 7 years, 53% female) ...
Grioni Alessandro - - 2014
Reference intervals for blood biochemical analytes and packed cell volume are useful to veterinarians and conservation programs for monitoring the health of threatened species. Populations of the critically endangered Chinese three-striped box turtle, Cuora trifasciata (Bell, 1825), are heavily depleted in the wild because of overharvesting; and many individuals are ...
Maduell Francisco - - 2014
Introduction: On-line haemodiafiltration (OL-HDF) is based on the controlled administration of large volumes of replacement ultrapure dialysate to the extracorporeal blood circuit of dialysis. It is currently the most effective technique for eliminating small and large uraemic toxins. Recent studies have observed a direct association between a decrease in mortality ...
Abdelaal Mohammed Mahmoud MM Drs Abdelaal and Aboelatta are Associate Professors, Department of Plastic and Reconstructive Surgery, Faculty of Medicine, Ain-Shams University, Cairo, - - 2014
Laser-assisted liposuction has been associated with reduced blood loss. However, this clinical finding has not been evaluated objectively. In this study, the authors objectively estimated the blood loss volume associated with laser lipolysis vs traditional liposuction in various anatomic regions. In this prospective study, 56 patients underwent equal amounts of ...
Gray Kerryn K Forensic Science Service Tasmania, 20 St. Johns Avenue, New Town, Tasmania 7008, Australia. Electronic address: - - 2014
A significant number of evidence items submitted to Forensic Science Service Tasmania (FSST) are blood swabs or bloodstained items. Samples from these items routinely undergo phenol:chloroform:isoamyl alcohol organic extraction and quantitative Polymerase Chain Reaction (qPCR) testing prior to PowerPlex(®) 21 amplification. This multi-step process has significant cost and timeframe implications ...
Schneditz Daniel D 1Institute of Physiology, Medical University of Graz, Graz, Austria 2 Clinical Division of Nephrology, Department of Internal Medicine, Medical University of Graz, Graz, Austria 3KfH-Kuratorium für Dialyse und Nierentransplantation, KfH Kidney Center Berlin-Köpenick, Berlin, - - 2014
It was the aim to measure the distribution volume and the elimination of ultra-pure dialysate in stable hemodialysis patients during on-line hemodiafiltration (HDF).Dialysate was automatically infused as a volume indicator using standard on-line HDF equipment. Indicator concentration was non-invasively measured in the arterial blood-line (BVM, Fresenius Medical Care) and its ...
Popovic Katarina Surlan KS Institute of Radiology, University Medical Center Ljubljana, Ljubljana, Slovenia. Electronic address: - - 2014
We aimed to detect changes in the volume and perfusion parameters of the submandibular glands during and after radiochemotherapy. Twelve patients underwent computed tomography (CT) and perfusion CT before radiochemotherapy, after 40 Gy, after 70 Gy, and 3 months after radiochemotherapy. Submandibular gland volume, blood volume, permeability surface area product, and blood flow ...
Zuckerwise Lisa C LC Department of Obstetrics, Gynecology, and Reproductive Sciences, Section of Maternal Fetal Medicine, Yale School of Medicine, New Haven, - - 2014
Visual estimation of blood loss is often inaccurate and imprecise. Obstetric bleeding requires expedient identification and intervention to prevent maternal morbidity and mortality. We aimed to create a visual aid to improve accuracy of estimated obstetric blood loss. We designed a pocket card containing images of blood on common obstetric ...
Gómez Daniel O DO Instituto de Astronomía y Física del Espacio, C.C. 67 Suc. 28, 1428 Buenos Aires, - - 2014
We study the stability of shear flows in a fully ionized plasma. Kelvin-Helmholtz is a well-known macroscopic and ideal shear-driven instability. In sufficiently low-density plasmas, also the microscopic Hall magnetoshear instability can take place. We performed three-dimensional simulations of the Hall-magnetohydrodynamic equations where these two instabilities are present, and carried ...
Grady Mike M LifeScan Scotland Ltd, Inverness, UK - - 2014
There is a perception that patients with diabetes struggle to produce sufficient blood to fill glucose test strips, including strips with 1-µL fill requirements. The purpose of this study was to determine the volume of blood expressed when these patients perform routine fingersticks using their own lancing device and sampling ...
Miller Wayne L WL Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota. Electronic address: - - 2014
This study sought to quantitate total blood volume (TBV) in patients hospitalized for decompensated chronic heart failure (DCHF) and to determine the extent of volume overload, and the magnitude and distribution of blood volume and body water changes following diuretic therapy. The accurate assessment and management of volume overload in ...
Zaar Morten M aDepartment of Anaesthesia bDepartment of Clinical Immunology, Rigshospitalet cDepartment of Anaesthesia, Bispebjerg Hospital, University of Copenhagen, Copenhagen, Denmark dDepartment of Surgery, Center for Translational Injury Research, CeTIR, University of Texas Medical School, Houston, Texas, - - 2014
The coagulation system is activated by a reduction of the central blood volume during orthostatic stress and lower body negative pressure suggesting that also a blood loss enhances coagulation. During bleeding, however, the central blood volume is supported by fluid recruitment to the circulation and redistribution of the blood volume. ...
Park Chan-Seong CS Central District Office of National Forensic Service, Daejeon, 305-348, - - 2014
In bloodstain pattern analysis, the blood droplet volume and surface impact velocity play an important role, and many related experimental studies have been carried out. If an appropriate computational fluid dynamics (CFD) model that could solve bloodstain patterns, especially spine formation bloodstain patterns, can be obtained, the blood droplet volume ...
Whiting S D SD Faculty of Engineering, Health, Science and Environment, Charles Darwin University, Darwin, NT 0909, - - 2014
In recent years, the use of blood chemistry as a diagnostic tool for sea turtles has been demonstrated, but much of its effectiveness relies on reference intervals. The first comprehensive blood chemistry values for healthy wild hawksbill (Eretmochelys imbricata) sea turtles are presented. Nineteen blood chemistry analytes and packed cell ...
Schneditz Daniel D 1Institute of Physiology, Medical University of Graz, Graz, Austria 2 Clinical Division of Nephrology, Department of Internal Medicine, Medical University of Graz, Graz, - - 2014
A technique to measure absolute blood volume and hepato-splanchnic blood flow (Qh) during hemodialysis (HD) is explored.The dispersion and elimination of indocyanine-green (ICG) was measured using a non-invasive optical device attached to the extracorporeal system and compared to transcutaneous measurements. Distribution volume (V) and elimination rate constant (k) were determined ...
Lin Chun-Jen CJ Department of Neurology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; Department of Internal Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, - - 2014
Orthostatic intolerance (OI) is common but heterogeneous. There is a subgroup of OI patients who have excessive decrease in cerebral blood flow velocity (CBFV) of bilateral middle cerebral arteries (MCAs) during head-up tilt without systemic blood pressure change. This study evaluated the role of blood volume reduction in such patients. ...
Hodge Ashley B - - 2014
Whole blood from the heart-lung (bypass) machine may be processed through a cell salvaging device (i.e., cell saver [CS]) and subsequently administered to the patient during cardiac surgery. It was determined at our institution that CS volume was being discarded. A multidisciplinary team consisting of anesthesiologists, perfusionists, intensive care physicians, ...
Dusik Chris J CJ The Department of Surgery, Section of Orthopaedics, University of Calgary, Calgary, - - 2014
Arthroplasty entails considerable exposure to allogenic blood transfusion. Cell salvage with washing is a contemporary strategy that is not universally used despite considerable potential benefits. We searched Embase and Medline to determine if blood salvage with washing during primary and/or revision hip and knee arthroplasty results in lower rates of ...
Sharma Ashish A Departments of Radiation Oncology, Surgery and Medicine, Medical College of Wisconsin, Milwaukee, - - 2014
The collection of blood samples from laboratory rats requires the use of bleeding techniques that provide quality samples of sufficient volume for analysis without injury to the animal. Retro-orbital bleeding (ROB) is a phlebotomy technique that can yield high-quality samples of adequate volume, but it has been criticized for its ...
Pérez-Muñuzuri Vicente V Group of Nonlinear Physics, Faculty of Physics, University of Santiago de Compostela, E-15782, Santiago de Compostela, - - 2014
The effect of compressibility on the mixing of Lagrangian tracers is analyzed in chaotic stirred flows. Mixing is studied in terms of the finite-time Lyapunov exponents. Mixing and clustering of passive tracers surrounded by Lagrangian coherent structures is observed to increase with compressibility intensity. The role of the stirring rate ...
Caroff Jildaz J Beaujon Medical Center, NEURI-Interventional Neuroradiology, Paris Diderot University, 100, Boulevard Général Leclerc, 92110, Clichy, France, - - 2014
Cerebral blood volume (CBV) measurement by flat panel detector CT (FPCT) in the angiography suite seems to be a promising tool for patient management during endovascular therapies. A steady state of contrast agent distribution is mandatory during acquisition for accurate FPCT CBV assessment. To the best of our knowledge, this ...
Shaban Mona Mohamed MM Department of Obstetrics and Gynecology, Faculty of Medicine, Cairo University , Cairo , - - 2014
Abstract The aim of the study was to assess correlation of ultrasonographic markers of ovarian reserve and IVF/ICSI outcome. Two-hundred twelve IVF/ICSI patients were included. Upon pituitary suppression confirmation, antral follicle count (AFC), ovarian volume (OV), and ovarian stromal indices [vascularization index (VI), flow index (FI), and vascularization flow index ...
Reed Nicki N 1Royal (Dick) School of Veterinary Studies, University of Edinburgh, Easter Bush, Edinburgh, - - 2014
This retrospective study aimed to identify the most accurate formula for estimating the increase in packed cell volume (PCV) after whole blood transfusion of cats, as several formulae have been reported but not validated. Forty cats, of varying breeds and gender, were included from two referral institutions after database searches ...
Gao Hongzhi - - 2014
Subtracted blood volume spectrometry (SBVS) can eliminate the background information in near infrared spectroscopy (NIRS) noninvasive biochemical sensing. However, the spectrum obtained by this method is accompanied by serious noises which are to the disadvantage of the calibration models. Empirical mode decomposition (EMD) was applied to restrict the noises in ...
Bouwens Arno - - 2014
Quantitative three-dimensional blood flow imaging is a valuable technique to investigate the physiology of the brain. Two-photon microscopy (2PM) allows quantification of the local blood flow velocity with micrometric resolution by performing repeated line scans, but prohibitively long measurement times would be required to apply this technique to full three-dimensional ...
Philip Joseph J Department of Transfusion Medicine, Armed Forces Medical College, Pune, - - 2014
Vasovagal reactions (VVRs) in blood donors. To find an association of age, sex, donation status, weight, total blood volume and volume of blood collected with occurrence of immediate VVR. Retrospective single-centre study. The study was conducted from March 2000 to November 2010 at a tertiary care blood transfusion centre. All ...
Li Dachao D State Key Laboratory of Precision Measuring Technology and Instruments, Tianjin University, Tianjin 300072, China. - - 2014
It is difficult to accurately measure the volume of transdermally extracted interstitial fluid (ISF), which is important for improving blood glucose prediction accuracy. Skin resistance, which is a good indicator of skin permeability, can be used to determine the volume of extracted ISF. However, it is a challenge to realize ...
Farag Ehab E Department of General Anesthesiology, Anesthesiology Institute, Cleveland Clinic, Cleveland, OH ; Department of Outcomes Research, Anesthesiology Institute, Cleveland Clinic, Cleveland, - - 2014
Postoperative vision loss (POVL) after spine surgery is a rare but devastating outcome. We present the first case-control study from a single institution for POVL with the diagnoses of ischemic optic neuropathy or central vision loss after complex spine surgery. POVL cases following spine surgeries between December 1995 and December ...
Nicińska B B Department of Anesthesiology and Intensive Care Unit, Medical University of Warsaw, Clinical Hospital Dzieciątka Jezus, Warsaw, - - 2014
Dilutional coagulopathy might cause life-threatening hemorrhages in liver transplantation. Liver insufficiency is usually accompanied by alteration in fibrinogen (Fib) synthesis, which is one of the main clotting factors providing appropriate hemostasis. Intraoperative hemodilution results in further Fib concentration reduction enhancing coagulopathy and blood loss. Exogenous Fib substitution might prevent this. ...
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