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Chenouard Alexis A Pediatric Department, Nantes University Hospital, Boulevard Jean Monnet, 44093, Nantes, France, - - 2014
GLUT-1-deficiency syndrome (GLUT1-DS; OMIM 606777) is a treatable metabolic disorder caused by a mutation of SLC2A1 gene. The functional deficiency of the GLUT1 protein leads to an impaired glucose transport into the brain, resulting in neurologic disorders.We report on a 6-month-old boy with preprandial malaises who was treated monthly by ...
Aas Camilla Bakken - - 2014
Arctic animals undergo large seasonal fluctuations in body weight. The effect of body condition on the distribution and composition of 16 perfluoroalkyl substances (PFASs) was investigated in liver, blood, kidney, adipose tissue and muscle of Arctic foxes (Vulpes lagopus) from Svalbard (n=18, age 1-3 years). PFAS concentrations were generally highest ...
Schoknecht Karl K Institute for Neurophysiology, Charité-University Medicine Berlin, Berlin, - - 2014
Focal cerebral ischemia is among the main causes of death and disability worldwide. The ischemic core often progresses, invading the peri-ischemic brain; however, assessing the propensity of the peri-ischemic brain to undergo secondary damage, understanding the underlying mechanisms, and adjusting treatment accordingly remain clinically unmet challenges. A significant hallmark of ...
Golab Hd H Department of Cardiothoracic Surgery, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands - - 2014
Priming-related hemodilution is the culprit behind excessive body water accumulation, postoperative coagulopathy and enhanced blood transfusion in infant cardiac surgery patients. In this retrospective, observational study, clinical data were analyzed to assess the effect of conventional ultrafiltration on allogenic blood transfusion and patient clinical outcome. All infants with a bodyweight ...
Asıcıoglu Osman O Department of Obstetrics and Gynecology, Şişli Etfal Education and Research Hospital, Istanbul, - - 2014
Objective The aim of this study is to assess the effect of placental drainage during active management of the third stage of labor on reducing both blood loss and the length of the third stage. Study Design This prospective randomized controlled trial included 485 patients who underwent vaginal delivery in two tertiary ...
Tu Wen-Zhan WZ Department of Physical Medicine and Rehabilitation, the Second Affiliated Hospital of Wenzhou Medical College, Wenzhou, Zhejiang Province, 325027, - - 2014
Gua Sha and Blood-letting at the acupoints were Chinese traditional therapies for heatstroke. The purpose of present study was to assess the therapeutic effect of Gua Sha on the DU Meridian and Bladder Meridian combined with Blood-letting acupoints at Shixuan (EX-UE 11) and Weizhong (BL 40) on heatstroke. Anesthetized rats, ...
Credille B C BC Department of Population Health, College of Veterinary Medicine, University of Georgia, Athens, - - 2014
Acute puerperal metritis (APM) affects 30% of postpartum dairy cattle. Bacteremia negatively impacts survival in cattle with coliform mastitis. However, the prevalence of bacteremia in dairy cattle with APM is unknown. Bacteremia is detectable in a large proportion of cattle with APM. Seventeen dairy cows with APM and 17 healthy ...
Fazio Francesco F Department of Veterinary Sciences, Polo Universitario Annunziata, University of - - 2014
Haptoglobin (Hp), serum amyloid A (SAA), C-reactive protein (CRP), white blood cells (WBC), reactive oxygen metabolites (ROMs), the antioxidant barrier (Oxy-adsorbent) and thiol groups of plasma compounds (SHp) were measured in ten dogs that had been transported a distance of about 230 km within 2 h (experimental group) and in ...
Törnudd Mattias M Departments of Cardiovascular and Thoracic Anesthesia, Faculty of Health Sciences, Linköping University, Linköping, - - 2014
The purpose of this study was to examine the isovolumetric distribution kinetics of crystalloid fluid during cardiopulmonary bypass. Ten patients undergoing coronary artery bypass grafting participated in this prospective observational study. The blood hemoglobin and the serum albumin and sodium concentrations were measured repeatedly during the distribution of priming solution ...
Xu Qingyan - - 2014
To investigate the influence of heated moxa sticks ("moxibustion") and Daiwenjiu ointment (DO) on changes in temperature and blood perfusion volume on the skin of the backs of healthy subjects. DO was spread on the left side of the body, and the right side of the body was treated with ...
Ahmed Magdy Refaat MR Department of Obstetrics and Gynecology, Faculty of Medicine, Suez Canal University , Ismailia , Egypt - - 2014
Abstract Objective: To evaluate the efficacy of tranexamic acid (TA) in decreasing blood loss during and after elective caesarean section (CS). Methods: This prospective randomized trial was conducted among 124 pregnant women subjected to term elective CS. Patients were equally divided into two groups. Study group received 10 mg/kg TA intravenously ...
Busardò Francesco Paolo FP Department of Anatomical, Histological, Forensic and Orthopaedic Sciences, Sapienza University of Rome, Viale Regina Elena 336, 00161, Rome, Italy. Electronic address: - - 2014
Gamma-hydroxybutyrate (GHB) is a central nervous system depressant, primarily used as a recreational drug of abuse with numerous names. It has also been involved in various instances of drug-facilitated sexual assault due to its potential incapacitating effects. The first aim of this paper is to measure the post-mortem concentration of ...
Bertlich Mattis M * Department of Otorhinolaryngology, Head and Neck Surgery, University Medical Center Göttingen , - - 2014
Objective: Betahistine is a histamine-like drug that is used in the treatment of Ménière's disease. It is commonly believed that betahistine increases cochlear blood flow and thus decreases the endolymphatic hydrops that is the cause of Ménière's. Despite common clinical use, there is little understanding of the kinetics or effects ...
Romanò Carlo L CL Department of Bone and Joint Infections and Reconstructive Surgery, IRCCS Orthopaedic Institute Galeazzi, Via Riccardo Galeazzi 4, 20161, Milan, Italy, - - 2014
The aim of the present study was to assess the efficacy of a thrombin-based topical haemostatic in reducing blood requirements after total knee replacement (TKR) revision surgery. This prospective, randomized, controlled study was designed to evaluate the haemostatic efficacy and safety of a thrombin-based topical haemostatic (Floseal) versus standard treatment ...
Hao Na N Department of Neurology, First Norman Bethune Hospital of Jilin University, Changchun, - - 2014
We compared two contrast agents, agitated saline and agitated saline with blood, with respect to their efficacy in the diagnosis of right-to-left shunt with contrast-enhanced transcranial Doppler. Three hundred thirty Chinese patients underwent examinations with one of four different methods in random order: (i) 9 mL agitated saline solution with 1 mL ...
Frank Steven M - - 2014
BackgroundA relatively new method of electrocautery, the radiofrequency bipolar hemostatic sealer (RBHS), uses saline-cooled delivery of energy, which seals blood vessels rather than burning them. We assessed the benefits of RBHS as a blood conservation strategy in adult patients undergoing multilevel spinal fusion surgery.MethodsIn a retrospective cohort study, we compared ...
Salanova Marisa - - 2014
The aim of this study is to extend the Channel Model of Flow (Csikszentmihalyi, 1975, 1990) at the collective level (workgroups) by including collective efficacy beliefs as a predictor of collective flow based on the Social Cognitive Theory (Bandura, 1997, 2001). A two-wave longitudinal lab study was conducted with 250 ...
Forster Michael A MA ICT International, Armidale, New South Wales, Australia School of Agriculture and Food Sciences, The University of Queensland, St Lucia, Queensland, Australia - - 2014
Nocturnal sap flow (Qn) has been found to occur across many taxa, seasons and biomes. There is no general understanding as to how much Qn occurs and whether it is a significant contribution to total daily sap flow (Q). A synthesis of the literature and unpublished data was made to ...
Mulaj Muj M Department of Anesthesiology, Centre Hospitalier Universitaire Brugmann and Queen Fabiola Children's University Hospital, Brussels, - - 2014
Red blood cell (RBC) transfusion is frequently required in pediatric cardiac surgery and is associated with altered outcome and increased costs. Determining which factors predict transfusion in this context will enable clinicians to adopt strategies that will reduce the risk of RBC transfusion. This study aimed to assess predictive factors ...
Franchini Massimo - - 2014
ABO blood group antigens are complex carbohydrate molecules expressed on the surface of red blood cells and a variety of human cells and tissues. It is well known that ABO blood type exerts a profound influence on hemostasis, being a major determinant of von Willebrand factor (VWF), and consequently factor ...
Jackson Hope T HT Department of Surgery, George Washington University School of Medicine & Health Sciences, Washington, District of - - 2014
Blood products containing leukocytes have been associated with negative immunomodulatory and infectious effects. Transfusion-related acute lung injury is partially explained by leucocyte agglutination. The Food and Drug Administration has therefore recommended leukoreduction strategies for blood product transfusion. Our institution has been using leukocyte-reduced blood via filtration for neonates on Extracorporeal ...
Chinde Srinivas S Toxicology Unit, Biology Division, Indian Institute of Chemical Technology, Hyderabad, Andhra Pradesh, 500007, - - 2014
The genotoxicological effects in 200 lead acid storage battery recycling and manufacturing industry workers in Hyderabad along with matched 200 controls were studied. The genetic damage was determined by comet, micronucleus (MN), and chromosomal aberration (CA) test in peripheral blood lymphocytes (PBL). The MN test was also carried out in ...
Fong Shirley S M SS Institute of Human Performance, University of Hong Kong, Pokfulam, Hong Kong, China, - - 2014
Survivors of nasopharyngeal cancer (NPC) often sustain cardiovascular complications after conventional cancer treatments. Tai Chi (TC) Qigong training may be a viable way to improve peripheral circulatory status and aerobic capacity in this population. The objective of this study was to evaluate the effects of a 6-month TC Qigong training ...
Ferreira Rui R F RR Department of Veterinary Clinics, Institute for Biomedical Sciences of Abel Salazar, University of Porto, 4050-313 Porto, - - 2014
Objective-To evaluate the bone marrow regenerative response and iron status of canine blood donors subjected to repeated blood collections for 1 year. Design-Prospective cohort study. Animals-57 blood donor dogs. Procedures-Hematologic variables, including reticulocyte percentage, were evaluated before and 10 days after each blood collection in 16 dogs donating 13% of ...
Lim Mi Hyun MH Department of Physiology (M.H.L., A.R.S., S.R.P.), Inha Research Institute for Medical Sciences (J.K.), and Division of Biomedical and Bioengineering Sciences (B.H.C.), Inha University College of Medicine, Incheon, Korea; and Departments of Orthopedic Surgery (B.-H.M.) and Physiology (E.J.B.), Ajou University School of Medicine, Suwon, - - 2014
To determine whether low-intensity ultrasound (US) can reduce red blood cell (RBC) edema and, if so, whether the US activity is associated with aquaporin 1 (AQP-1), a water channel in the cell membrane. Red blood cell edema was induced by gramicidin D treatment at 40 ng/mL for 20 minutes and ...
Thomassen B J W BJ Medical Center Haaglanden, Department of Orthopaedic Surgery , Lijnbaan 32, 2501 CK Den Haag, The - - 2014
We hypothesised there was no clinical value in using an autologous blood transfusion (ABT) drain in either primary total hip (THR) or total knee replacement (TKR) in terms of limiting allogeneic blood transfusions when a modern restrictive blood management regime was followed. A total of 575 patients (65.2% men), with ...
Hui Lei L Department of Neurosurgery, The First Affiliated Hospital of Xinxiang Medical University, Weihui, Henan 453100, P.R. - - 2014
The aim of the present study was to investigate the effects of ulinastatin on cerebral oxygen metabolism and C-reactive protein (CRP) levels in patients with severe traumatic brain injury (sTBI). A total of 92 patients with sTBI, admitted to the First Affiliated Hospital of Xinxiang Medical University (Xinxiang, China), were ...
Hunter Allison A Radiology Oral Health and Diagnostic Sciences, Georgia Regents University, College of Dental Medicine, Augusta, GA, - - 2014
This study assessed the effectiveness of three antimicrobial mouthrinses in reducing microbial growth on photostimulable phosphor (PSP) plates. Prior to performing a full-mouth radiographic survey (FMX), subjects were asked to rinse with one of the three test rinses (Listerine®, Decapinol®, or chlorhexidine oral rinse 0.12%) or to refrain from rinsing. ...
Cem Arıtürk A Department of Cardiovascular Surgery, Acıbadem University School of Medicine, Atasehir, Istanbul, - - 2014
Introduction: Clear guidelines for red cell transfusion during cardiac surgery have not yet been established. The current focus on blood conservation during cardiac surgery has increased the urgency to determine the minimum safe hematocrit for these patients. The aim of this study was to determine whether monitoring of cerebral regional ...
Burgert James M - - 2014
This prospective, experimental, mixed study determined whether there were differences in intraosseous (IO) and intravenous (IV) whole blood transfusion relative to hemolysis and transfusion time. Swine were assigned to the IV group (n = 6) with an 18-gauge catheter in the auricular vein or the IO group (n = 7) ...
Vega Rafael A RA Departments of Neurosurgery - - 2014
Object Children with craniosynostosis may require cranial vault remodeling to prevent or relieve elevated intracranial pressure and to correct the underlying craniofacial abnormalities. The procedure is typically associated with significant blood loss and high transfusion rates. The risks associated with transfusions are well documented and include transmission of infectious agents, ...
McRobb Craig M CM Children's Hospital Colorado, Aurora, CO, USA - - 2014
There have been numerous recent advances geared specifically toward the practice of pediatric cardiopulmonary bypass (CPB). These advances include the development of the first oxygenator intended solely for the neonatal CPB patient; pediatric oxygenators with low prime volumes and surface areas, which allow flows up to 2 L/min; pediatric oxygenators ...
Li Qian Q Department of Anesthesiology and Translational Neuroscience Center, West China Hospital, Sichuan University , Chengdu, Sichuan , P. R. - - 2014
In order to investigate whether hemoglobin-based oxygen carrier (HBOC) attenuates cardiopulmonary bypass (CPB)-induced cerebral damage. Male adult Beagle dogs were randomly divided into sham, control, and HBOC groups. After establishment of CPB model, hearts were arrested for 2 h and reperfused for 2 h. HBOC improved intracerebral O2 tensions and ...
Karakuş Osman Z OZ Department of Pediatric Surgery, Dokuz Eylul University, Medical School, İzmir, - - 2014
Introduction Intestinal damage has been shown to occur when intra-amniotic meconium concentration exceeds threshold level. However, the mechanism of the meconium-induced intestinal damage is still unclear. Intestinal ischemia can cause intestinal damage in gastroschisis. This study was aimed to determine the effects of intra-amniotic meconium on the contractility of superior mesenteric ...
Amaratunga Chanaki C Laboratory of Malaria and Vector Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, - - 2014
The ring-stage survival assay (RSA) is a powerful tool for phenotyping artemisinin-resistant Plasmodium falciparum, but requires experienced microscopists to count viable parasites among 10,000 erythrocytes in Giemsa-stained thin blood smears. Here we describe a rapid flow cytometric assay that accurately counts viable parasites among 250,000 erythrocytes in suspension. This method ...
Seyfizadeh Nayer N MSc of clinical biochemistry, Tabriz University of Medical Science, Tabriz, - - 2014
Abstract There are four major blood groups in human based on the presence of A and B antigens. ABO gene encodes A and B antigens on the surface of red blood cells and there are reported relations between this blood phenotype and pregnancy outcomes in the women. In this study, ...
Ranucci M M Departments of Cardiothoracic - Vascular Anesthesia and Intensive Care, IRCCS Policlinico San Donato, Milan, Italy - - 2014
Excessive hemodilution during cardiopulmonary bypass (CPB) is associated with an increased rate of red blood cell (RBC) transfusion and acute kidney injury (AKI). Minimization of the oxygenator priming volume is a measure to contain hemodilution. In this study, we evaluated the new oxygenator, Sorin Inspire 6™, with respect to its ...
Yamamoto Koji - - 2014
Repair of thoracic aortic aneurysm (TAA) is often associated with massive hemorrhage aggravated by dilutional coagulopathy with severe hypofibrinogenemia. Although only fresh frozen plasma (FFP) is available for acquired hypofibrinogenemia in Japan, the hemostatic effect of FFP has not been enough for dilutional coagulopathy in TAA surgery. There are increasing ...
Vasile Francesca F Universita' degli Studi di Milano, Dipartimento di Chimica, via Golgi 19, 20133 Milano, - - 2014
Cholera is a diarrheal disease responsible for the deaths of thousands, possibly even hundreds of thousands of people every year, and its impact is predicted to further increase with climate change. It has been known since decades that blood group O individuals suffer more severe symptoms of cholera compared to ...
Yang Yang Y Third Hospital of Hebei Medical University, 050051, Shijiazhuang, People's Republic of - - 2014
The objective of this randomized controlled trial was to evaluate the efficacy and safety of intra-articular injections of tranexamic acid (TXA) on perioperative blood loss and transfusion in primary unilateral total knee arthroplasty (TKA) without drainage. Primary TKA was performed on a total of 80 patients (80 knees) affected to ...
Marinkovic Ivan I Department of Neurology, Helsinki University Central Hospital, Helsinki, Finland; Experimental MRI Laboratory, Biomedicum, Helsinki, Finland. Electronic address: - - 2014
Intracerebral hemorrhage (ICH) is the least treatable form of stroke and is associated with the worst prognosis. In up to 40% of cases, ICH is further complicated by intraventricular hemorrhage (IVH), which predisposes to hydrocephalus, and increases case-mortality to 80%. However, IVH is not present in widely used preclinical models ...
Jiwaji Zoeb Z Anaesthetics and Critical Care, Royal Infirmary of Edinburgh and the MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United - - 2014
Transfused blood may have immunomodulatory and proinflammatory effects. We report the first randomized study exploring whether leukoreduced red blood cell (RBC) transfusion increases circulating proinflammatory mediators, markers of neutrophil activation, and the acute-phase response in critically ill adults. Eighty-four patients were recruited from six general intensive care units in the ...
Donndorf Peter P Department of Cardiac Surgery, University of Rostock, Rostock, - - 2014
Closed minimal extracorporeal circulation (MECC) systems currently do not represent the standard of surgical care for open-heart surgery. Yet, considering the beneficial results reported for coronary artery bypass graft (CABG) surgery, we used an MECC system in aortic valve replacement (AVR) and analysed the effects on intraoperative microvascular perfusion in ...
Kanak Mazhar A MA 1 The Institute of Biomedical Studies, Baylor University, Waco, TX. 2 Islet Cell Laboratory, Baylor Research Institute, Dallas, TX. 3 Baylor Annette C. and Harold C. Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX. 4 Address correspondence to: Bashoo Naziruddin, Ph.D., 3410 Worth Street, Suite 950, Dallas, TX - - 2014
The instant blood-mediated inflammatory response (IBMIR) has been shown as a major factor that causes damage to transplanted islets. Withaferin A (WA), an inhibitor of nuclear factor (NF) κB, was shown to suppress the inflammatory response in islets and improve syngeneic islet graft survival in mice. We investigated how treating ...
Quirico P E PE Center for the Study of Natural and Physical Therapies (CSTNF), Corso Galileo Ferraris, 164, 10134, Turin, Italy, - - 2014
Acupuncture has been proven to be effective in the treatment of various cardiovascular disorders; it acts both on the peripheral flow and on the cerebral flow. Our study aimed to evaluate the effects of the insertion of PC 6 Neiguan and LR 3 Taichong acupoints on the cerebral blood flow ...
Raut Monish S MS Department of Cardiac Anaesthesia, BLK Hospital, New Delhi, - - 2014
An 11-year-old child, a known case of sickle cell anaemia with a history suggestive of sickling crisis in the past was scheduled for surgical pulmonary valvotomy. Pre-operative blood transfusion and hydroxyurea were administered. Pre-operative blood transfusion is indicated in sickle cell disease patients to raise the haematocrit level and lower ...
Sharif Saima S Dr. Saima Sharif, Assistant Professor, Department of Zoology, Lahore College for Women University, Lahore, - - 2014
To determine if there is any significant association between ABO blood groups and ischemic heart disease (IHD). The study was performed at Punjab Institute of Cardiology (PIC), Lahore. Study duration was from January 2012 to September 2012. This study included 200 IHD patients and 230 control individuals. Self design questionnaire ...
Dakir Abu A Reader, Department of Oral and Maxillofacial Surgery, Sree Balaji Dental College and Hospital , Pallikaranai, Chennai, India - - 2014
Tranexamic acid (TXA) is prescribed for short term management of haemorrhage. It is also administered prophylatically in surgeries where blood loss is anticipated. Tranexamic mouth washes are also used in oral surgical procedures for patients with coagulopathies. The purpose of this study was to assess the efficiency of the usage ...
van Leeuwen Sander S SS Microbial Physiology, Groningen Biomolecular Sciences and Biotechnology Institute (GBB), University of Groningen, Nijenborgh 7, NL-9747 AG Groningen, The - - 2014
Human milk oligosaccharides (HMOs) are a major constituent of human breast milk and play an important role in reducing the risk of infections in infants. The structures of these HMOs show similarities with blood group antigens in protein glycosylation, in particular in relation to fucosylation in Lewis blood group-type epitopes, ...
Sun Peng P State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, 651 Dong Feng RD East, 510060, Guangzhou, Guangdong Province, People's Republic of - - 2014
The association between clinical characteristics, prognosis, and the ABO blood group of esophageal squamous cell carcinoma (ESCC) is rarely discussed. The aims of the current study were to investigate the correlation of the ABO blood group with the clinicopathological characteristics in a consecutive cohort of patients with ESCC and to ...
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