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Carcillo Joseph A JA Department of Critical Care Medicine and Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, - - 2014
To review the past year's literature, and selected prior literature relevant to these most recent findings, regarding intravenous fluid choices in the management of critically ill children. Twenty-eight publications were identified using the keywords pediatrics and intravenous fluid in the PubMed database. The subjects identified included intravenous fluid choices related ...
Galarza Marcelo - - 2014
Based on a landmark study by Lin et al of the 2-dimensional flow in ventricular catheters (VC) via computational fluid dynamics (CFD), we studied in a previous paper the 3-dimensional flow patterns of 5 commercially available VC. We calculated that most of the total fluid mass flows through the catheter's ...
Madden Jesse L JL Divisions of 1Cardiothoracic Surgery and 2Cardiology and 3Department of Molecular Medicine, University of Utah, Salt Lake City, - - 2014
Continuous-flow left ventricular assist devices (LVADs) subject elements of the blood to significant stress, resulting in clinically significant and subclinical hemolysis. We sought to prospectively determine if baseline red cell osmotic fragility of an advanced heart failure patient - influences the hemolytic response to LVAD support. Osmotic fragility assesses the ...
Fullard Luke L Institute of Fundamental Sciences, Massey University, Palmerston North, New Zealand. - - 2014
Three longitudinal motions of the rabbit small intestine were modelled in the CFD software Polyflow using ex vivo experimental data previously reported in literature. Consideration was given to chyme rheology and mixing performance of the macro-scale lumenal motions, as triggered by the observed wall motions. Simulations were performed to qualitatively ...
Ruef Peter P Department of Pediatrics, Clinic of Neonatology, University of Heidelberg, Germany. - - 2014
The low shear viscometer LS300 permits measurements of viscosity with the same precision of the LS30 but is now fully controlled by the windows based software. That allows to determine viscosity at several shear rates and to establish flow curves enabling determination of the viscosity of non-Newtonian fluids. The viscosity ...
Nieto Jorge E JE Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California, Davis, - - 2014
To compare 3 portable handheld analyzers with a bench top blood gas analyzer for measurement of blood and peritoneal fluid L-lactate concentrations in horses admitted with signs of colic. Prospective clinical study. Blood and peritoneal fluid from horses with colic. L-lactate concentrations in heparinized blood and peritoneal fluid were measured ...
Lee C C Institut Lumière Matière, Université Claude Bernard Lyon 1-CNRS, UMR 5306, Université de Lyon, F-69622 Villeurbanne Cedex, France and School of Aerospace and Mechanical Engineering, Korea Aerospace University, Goyang 412-791, - - 2014
Osmosis across membranes is intrinsically associated with the concept of semipermeability. Here, however, we demonstrate that osmotic flow can be generated by solute gradients across nonselective, fully permeable nanochannels. Using a fluorescence imaging technique, we are able to measure the water flow rate inside single nanochannels to an unprecedented sensitivity ...
Sampaio Pedro P CEDOC, Faculdade de Ciências Médicas, Universidade Nova de Lisboa, 1169-056 Lisboa, - - 2014
Internal organs are asymmetrically positioned inside the body. Embryonic motile cilia play an essential role in this process by generating a directional fluid flow inside the vertebrate left-right organizer. Detailed characterization of how fluid flow dynamics modulates laterality is lacking. We used zebrafish genetics to experimentally generate a range of ...
Lorenz B B FZ-Jülich, PGI, D-52425, Jülich, - - 2014
The fluid flow through a seal interface depends on the percolating non-contact channels morphology, size and length, and on the interfacial surface energies. In particular, hydrophobic interfaces may expel fluids and decrease the fluid flow of seals, while increasing the sliding friction. We present results of interfacial fluid flow experiments ...
Bleyer J J Laboratoire Navier, Université Paris-Est, Champs sur Marne, - - 2014
We study the flow, through a model two-dimensional porous medium, of Newtonian fluids, power-law fluids, and viscoplastic fluids in the laminar regime and with moderate or dominant effects of the yielding term. A numerical technique able to take properly into account yielding effects in viscoplastic flows without any regularization is ...
Schönecker Clarissa C Max-Planck-Institut für Polymerforschung, Mainz, - - 2014
The effect of the secondary fluid enclosed in the indentations of a superhydrophobic surface on electro-osmotic flow is investigated. We derive analytical expressions for the net electro-osmotic flow over periodically structured surfaces, accounting for the influence of dissipation within the secondary fluid as well as for the role of charges ...
Chevalier T T Université Paris-Est, Laboratoire Navier (UMR 8205), CNRS, ENPC, IFSTTAR, F-77420 Marne-la-Vallée, - - 2014
The present work addresses the problem of using Pulsed Field Gradient (PFG) experiments to measure velocity probability density functions and/or distributions in restricted flows, without being subjected to the blurring due to diffusive molecular motions. It especially focuses on two important classes of complex yield-stress fluids, i.e. water based colloidal ...
Chrysikopoulos Constantinos V - - 2014
The role of gravitational force on colloid transport in water-saturated columns packed with glass beads was investigated. Transport experiments were performed with colloids (clays: kaolinite KGa-1b, montmorillonite STx-1b). The packed columns were placed in various orientations (horizontal, vertical, and diagonal) and a steady flow rate of Q=1.5 mL/min was applied ...
Bordin José Rafael JR Campus Caçapava do Sul, Universidade Federal do Pampa, Av. Pedro Anunciação, s/n, CEP 96570-000, Caçapava do Sul, RS, - - 2014
We investigate through non-equilibrium molecular dynamic simulations the flow of anomalous fluids inside rigid nanotubes. Our results reveal an anomalous increase of the overall mass flux for nanotubes with sufficiently smaller radii. This is explained in terms of a transition from a single-file type of flow to the movement of ...
McGah Patrick M PM * University of Washington, Department of Mechanical Engineering † Seattle Children's Hospital and University of Washington, Department of - - 2014
Central venous catheters are often filled when not in use with an anti-coagulating fluid, usually heparinized saline, known as the locking fluid. However, the use of the locking fluid is associated with known risks due to "leakage" of the lock. A new hypothesis is proposed here to explain the lock ...
Palmiere Cristian C University Center of Legal Medicine, Lausanne University Hospital, Rue du Bugnon 21, 1011 Lausanne, Switzerland. Electronic address: - - 2014
β-hydroxybutyrate concentrations were determined in blood and synovial fluid in a series of medico-legal cases including hypothermia fatalities, individuals found dead in a cold environment and non-hypothermia cases with various, non-traumatic causes of death. Hypothermia was considered to be the cause of death according to circumstantial elements indicating exposure to ...
Arora Sanjay - - 2014
ABSTRACTObjectives:Blood glucose can be lowered via insulin and/or fluid administration. Insulin, although efficacious, can cause hypoglycemia and hypokalemia. Fluids do not cause hypoglycemia or hypokalemia, but the most effective route of fluid administration has not been well described. This study compared the efficacy and safety of oral versus intravenous fluids ...
Steinrigl Adolf - - 2014
Recently, research into alternative sample materials, such as oral fluid or filter-dried blood has been intensified, in order to facilitate cost-effective and animal-friendly sampling of individuals or groups of pigs for diagnostic purposes. The objective of this study was to compare the sensitivity of porcine reproductive and respiratory syndrome virus ...
Escalona-Arranz J C JC a Pharmacy Department , Oriente University , Avenida Patricio Lumumba s/n, 90500 Santiago de Cuba , - - 2014
Tamarind leaves are edible; however, their saponin content could be toxic to human blood cells. In this article, the effect of tamarind leaf fluid extract (TFE) on human blood cells was evaluated by using several tests. Results revealed that TFE did not cause significant haemolysis on human red blood cells ...
Giusti Serena S Research Center "E. Piaggio", University of Pisa, - - 2014
Permeability studies across epithelial barriers are of primary importance in drug delivery as well as in toxicology. However, traditional in vitro models do not adequately mimic the dynamic environment of physiological barriers. Here we describe a novel two-chamber modular bioreactor for dynamic in-vitro studies of epithelial cells. The fluid dynamic ...
Yamamoto Ayako A 1Department of Clinical Laboratory Medicine, Hirosaki University Graduate School of Medicine, Hirosaki, - - 2014
This study investigated a new method of flow cytometry (FCM) for analysis of red blood cell (RBC) osmotic fragility. Venous peripheral blood collected in a sampling tube coated with EDTA 2Na was analyzed using FCM to determine RBC osmotic fragility. RBCs were represented as a double-peaked forward scatter (FSC) histogram ...
Zhurova Mariia M Department of Laboratory Medicine and Pathology, 8249-114 Street, Edmonton, AB T6G 2R8, Canada; Research and Development, Canadian Blood Services, 8249-114 Street, Edmonton, AB T6G 2R8, - - 2014
The transfusion of red blood cells from umbilical cord blood (cord RBCs) is gathering significant interest for the treatment of fetal and neonatal anemia, due to its high content of fetal hemoglobin as well as numerous other potential benefits to fetuses and neonates. However, in order to establish a stable ...
Zhao Yanan Y Public Health Research Institute Center, New Jersey Medical School, Rutgers, The State University of New Jersey, Newark, NJ - - 2014
Using E. rostratum-specific and pan-fungal real-time PCR, we studied 24 blood samples and 2 synovial fluid specimens from 20 patients with persistent or worsening pain following injections of contaminated methylprednisolone. Seven blood specimens from 6 patients were significantly positive for fungal DNA by pan-fungal PCR with multiple fungal species identified.
Zhou Jianwei - - 2014
To date, the complete mechanism of rheumatoid arthritis (RA) remain unclear, T cells have been proposed to play an important role in the disease initiation and progression. Presently, some researchers have reported that there were skewed TCR Vβ in different samples of experimental animals or RA patients, such as in ...
Mehri Rym - - 2014
Background: The aim of the work presented in this paper is to design a microfluidic apparatus capable of providing controlled flow conditions suitable for Red Blood Cell (RBC) aggregation analysis. The linear velocity engendered from the controlled flow provides constant shear rates used to qualitatively analyze RBC aggregates. These controlled ...
Blum Martin M Institute of Zoology, University of Hohenheim, 70593 Stuttgart, - - 2014
Morphological asymmetry is a common feature of animal body plans, from shell coiling in snails to organ placement in humans. The signaling protein Nodal is key for determining this laterality. Many vertebrates, including humans, use cilia for breaking symmetry during embryonic development: rotating cilia produce a leftward flow of extracellular ...
Su B-C BC Department of Anesthesiology, Chang Gung Memorial Hospital, Tao-Yuan, - - 2014
Corrected flow time (FTc) has been utilized as preload indicator in recent literature. Accurate estimation of preload status during living donor liver donation (LDLD) is important due to fluid restriction. We evaluate the effectiveness of FTc as a surrogate of preload indicator during LDLD. Twenty-five patients undergoing LDLD were enrolled ...
Govey Peter M PM Division of Musculoskeletal Sciences, Department of Orthopaedics and Rehabilitation, Penn State College of Medicine, Hershey, PA 17033, - - 2014
Osteocytes, positioned within bone׳s porous structure, are subject to interstitial fluid flow upon whole bone loading. Such fluid flow is widely theorized to be a mechanical signal transduced by osteocytes, initiating a poorly understood cascade of signaling events mediating bone adaptation to mechanical load. The objective of this study was ...
Guo Wei W Mechanical Engineering Department, Florida State University, Tallahassee, FL - - 2014
Cryogenic flow visualization techniques have been proved in recent years to be a very powerful experimental method to study superfluid turbulence. Micron-sized solid particles and metastable helium molecules are specifically being used to investigate in detail the dynamics of quantum flows. These studies belong to a well-established, interdisciplinary line of ...
Fardin M A MA Université de Lyon, Laboratoire de Physique, École Normale Supérieure de Lyon, CNRS UMR 5672, 46 Allée d'Italie, 69364 Lyon Cedex 07, France. - - 2014
The flow between concentric cylinders is routinely used in soft matter studies. In many cases, the purpose of the setup is rheometric: the idea is to relate macroscopic changes in material properties to microscopic changes in the structure of the material. The correspondence between the modifications of the microscopic structure ...
Pooyath Lekshmy Venugopalan - - 2014
Controlled motion of artificial nanomotors in biological environments, such as blood, can lead to fascinating biomedical applications, ranging from targeted drug delivery to microsurgery, and many more. In spite of the various strategies used in fabricating and actuating nanomotors, practical issues related to fuel requirement, corrosion, and liquid viscosity have ...
Chilukuri Sandeep S Howard P Isermann Department of Chemical and Biological Engineering, Rensselaer Polytechnic Institute, Troy, NY 12180, USA. Center for Biotechnology and Interdisciplinary Studies, Rensselaer Polytechnic Institute, Troy, NY 12180, - - 2014
Swimming microorganisms have been previously observed to accumulate along walls in confined systems both experimentally and in computer simulations. Here, we use computer simulations of dilute populations for a simplified model of an organism to calculate the dynamics of swimmers between two walls with an external fluid flow. Simulations with ...
Lenski Markus - - 2014
Aim of this study was to evaluate the role of synovial interleukin-6 and synovial lactate for predicting native septic arthritis. We analyzed retrospectively synovial fluid parameters (interleukin-6, total-protein, glucose, lactate, synovial-fluid-white-blood-cell-count) of 62 patients with culture-verified native septic arthritis and compared them to 57 patients with acute aseptic arthritis. Receiver-Operating-Characteristic-curves ...
Deplano Valérie V Aix-Marseille Université, CNRS, Centrale Marseille, IRPHE UMR 7342, F-13384 Marseille, France. Electronic address: - - 2014
The aim of this work is to develop a unique in vitro set-up in order to analyse the influence of the shear thinning fluid-properties on the flow dynamics within the bulge of an abdominal aortic aneurysm (AAA). From an experimental point of view, the goals are to elaborate an analogue ...
Schneditz Daniel D 1Institute of Physiology, Medical University of Graz, Graz, Austria 2Division of Nephrology, Department of Internal Medicine, Medical University of Graz, Graz, - - 2014
Hemodialysis is accompanied by osmotic perturbations with distinct effects on red blood cell, plasma, and blood volumes. A series of in-vitro studies was done to analyze the separate effect on cell volume.Whole porcine blood was circulated through an extracorporeal circulation maintaining a constant blood volume. Hemoconcentration was continuously measured by ...
Stieger Tillmann T Stranski-Laboratorium für Physikalische und Theoretische Chemie, Technische Universität Berlin, Straße des 17. Juni 115, 10623 Berlin, - - 2014
We perform molecular dynamics simulations of a nematic liquid crystal flowing around a colloidal particle. We study the flow-induced modifications of the topological defects in the liquid crystal due to the presence of the colloid. We show that flow distorts Boojum defects into an asymmetrically larger downstream lobe, and that ...
Moon Ji Young JY School of Mechanical Engineering, Yonsei University, Seoul, - - 2014
Despite recent development of computational fluid dynamics (CFD) research, analysis of computational fluid dynamics of cerebral vessels has several limitations. Although blood is a non-Newtonian fluid, velocity and pressure fields were computed under the assumptions of incompressible, laminar, steady-state flows and Newtonian fluid dynamics. The pulsatile nature of blood flow ...
Gjerde Hallvard H 1Division of Forensic Medicine and Drug Abuse Research, Norwegian Institute of Public Health, PO Box 4404 Nydalen, 0403 Oslo, - - 2014
Oral fluid is an easily available specimen for studying drug use in a cohort or population. The prevalence of drugs in samples of oral fluid is the same as the prevalence in blood if using equivalent cutoff concentrations. The cutoffs in oral fluid may be higher or lower than that ...
Medby Christian C 1Norwegian Armed Forces Medical Services 2Dept. of Anaesthesia and Intensive Care, St. Olav University - - 2014
Crystalloids and colloids are used in prehospital fluid resuscitation to replace blood loss and preserve tissue perfusion until definite surgical control of bleeding can be achieved. However, large volumes of fluids will increase bleeding by elevating blood pressure, dislodging blood clots and by diluting coagulation factors and platelets. Hypotensive fluid ...
Walski Tomasz T Institute of Biomedical Engineering and Instrumentation, Wrocław University of Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland ; Regional Specialist Hospital in Wrocław, Research and Development Centre, Kamieńskiego 73a, 51-124 Wrocław, - - 2014
The aim of our experiments was to characterise and to validate the osmotic fragility test when applied to human blood samples with no significant alterations of osmotic fragility but with a differentiating shape of the haemolysis curve. All experiments were carried out on human erythrocytes taken from the Regional Centre ...
Khaled A-R A AR Mechanical Engineering Department, King Abdulaziz University, P.O. Box 80204, Jeddah 21589, Saudi - - 2014
Enhancement of heat transfers in counterflow plate heat exchanger due to presence of an intermediate auxiliary fluid flow is investigated. The intermediate auxiliary channel is supported by transverse conducting pins. The momentum and energy equations for the primary fluids are solved numerically and validated against a derived approximate analytical solution. ...
Lăcătuşu Diana - - 2014
To study effects of a perfluorocarbon emulsion on plasma and whole human blood viscosity in the presence of albumin or modified fluid gelatin. We investigated the effects of several PFC concentrations on plasma and whole blood viscosity in the presence of human albumin solution (HAS) or modified fluid gelatine (MFG; ...
Bucher Andreas M AM Department of Radiology and Radiological Science, Medical University of South Carolina, 25 Courtenay Drive MSC 226, Charleston, SC 29425, USA ; Department of Diagnostic and Interventional Radiology, Johann Wolfgang Goethe University Hospital, 60590 Frankfurt am Main, - - 2014
The exact pathophysiology of contrast-induced nephropathy (CIN) is not fully clarified, yet the osmotic characteristics of contrast media (CM) have been a significant focus in many investigations of CIN. Osmotic effects of CM specific to the kidney include transient decreases in blood flow, filtration fraction, and glomerular filtration rate. Potentially ...
Munawar Sufian S 0000-0001-8737-4803 Department of Mathematics and Basic Sciences, Prince Mohammad Bin Fahd University, Al Khobar 31952, Saudi Arabia ; Department of Informatics and Systems, University of Management and Technology, Lahore 54000, - - 2014
This study aims to investigate the unsteady boundary-layer flow of a viscoelastic non-Newtonian fluid over a flat surface. The plate is suddenly jerked to move with uniform velocity in a uniform stream of non-Newtonian fluid. Purely analytic solution to governing nonlinear equation is obtained. The solution is highly accurate and ...
Haavisto Sanna S Fibres and Biobased Materials, Rheology and Process Flows, VTT Technical Research Centre of Finland Jyväskylä, - - 2014
Flow properties of complex fluids such as colloidal suspensions, polymer solutions, fiber suspensions and blood have a vital function in many technological applications and biological systems. Yet, the basic knowledge on their properties is inadequate for many practical purposes. One important reason for this has been the lack of effective ...
Xu Yan Y Department of Forensic Medicine, Shanghai Medical College, Fudan University, Shanghai, China; Shanghai Key Laboratory of Crime Science Evidence, Key Laboratory of Forensic Evidence and Science Technology, Ministry of Public Security, Institute of Forensic Science, Shanghai Public Security Bureau, Shanghai, - - 2014
The identification of human body fluids or tissues through mRNA-based profiling is very useful for forensic investigations. Previous studies have shown mRNA biomarkers are effective to identify the origin of biological samples. In this study, we selected 16 tissue specific biomarkers to evaluate their specificities and sensitivities for human body ...
Ferrás L L LL Institute for Polymers and Composites/I3N, University of Minho, Campus de Azurém, 4800-058 Guimarães, Portugal. Electronic address: - - 2014
In this work we present semi-analytical solutions for the electro-osmotic annular flow of viscoelastic fluids modeled by the Linear and Exponential PTT models. The viscoelastic fluid flows in the axial direction between two concentric cylinders under the combined influences of electrokinetic and pressure forcings. The analysis invokes the Debye-Hückel approximation ...
Birngruber Thomas - - 2013
The blood-brain barrier (BBB) limits substance transport to the brain and is therefore the major hurdle to overcome when developing neuroactive drugs. Herein, we report on cerebral open flow microperfusion (cOFM) as a new membrane-free technique for measuring substance transport across the intact BBB. The cOFM technique is based on ...
Kuranuki Sachi - - 2013
Objective: To develop a minimally invasive interstitial fluid extraction technology (MIET) to monitor postprandial glucose area under the curve (AUC) without blood sampling, we evaluated the accuracy of glucose AUC measured by MIET and compared with that by blood sampling after food intake. Methods: Interstitial fluid glucose AUC (IG-AUC) following ...
Talon Laurent - - 2013
Simulating flow of a Bingham fluid in porous media still remains a challenging task as the yield stress may significantly alter the numerical stability and precision. We present a Lattice-Boltzmann TRT scheme that allows the resolution of this type of flow in stochastically reconstructed porous media. LB methods have an ...
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