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Gao Youhe Y National Key Laboratory of Medical Molecular Biology, Department of Pathophysiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences/School of Basic Medicine, 5 Dong Dan San Tiao, Beijing, China, - - 2015
Change is the soul of biomarker definition. Changes are more likely to be removed from blood because of homeostasis mechanisms of the body. Therefore, urine is probably a better biomarker source than blood. The road map to the urinary biomarker era is proposed. Researchers are reminded the potential opportunities and ...
Hadjinicolaou Maria M School of Science and Technology, Hellenic Open University, 11 Sahtouri str., GR-26 222, Patras, Greece, - - 2015
The rheological behaviour of low-density lipoprotein (LDL) particles within the blood plasma and their role in atherogenesis, as well as their ability to aggregate under certain circumstances, is the subject of many clinical tests and theoretical studies aiming at the prevention of atherosclerosis. In the present study we develop a ...
Hadjinicolaou Maria M School of Science and Technology, Hellenic Open University, 11 Sahtouri str., Patras, Greece, GR-26 222, - - 2015
Arteriosclerosis is a disease in which the artery walls get thicker and harder. Atherosclerosis is a specific form of arteriosclerosis which allows less blood to travel through the artery and increases blood pressure. Low-density lipoproteins (LDLs) and their ability to aggregate are important in atherosclerosis. In the present study we ...
Sand Claire A CA King's College - - 2014
Objective: Sepsis and sepsis-associated multi-organ failure represent the major cause of mortality in intensive care units worldwide. Cardiovascular dysfunction, a key component of sepsis pathogenesis, has received much research interest, though research translatability remains severely limited. There is a critical need for more comprehensive preclinical sepsis models, with more clinically ...
Budczies Jan J Institute of Pathology, Charité University Hospital, Charitéplatz 1, 10117 Berlin, Germany German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120 Heidelberg, Germany German Consortium for Translational Cancer Research (DKTK), Berlin partner site - - 2014
Semiconductor sequencing directly translates chemically encoded information (A, C, G or T) into voltage signals that are detected by a semiconductor device. Changes of pH value and thereby of the electric potential in the reaction well are detected during strand synthesis from nucleotides provided in cyclic repeated flows for each ...
Kottapalli Ajay Giri Prakash - - 2014
Evolution bestowed the blind cavefish with a resourcefully designed lateral-line of sensors that play an essential role in many important tasks including object detection and avoidance, energy efficient maneuvering, rheotaxis etc. Biologists identified the two types of vital sensors on the fish bodies called the superficial neuromasts and the canal ...
Wada Yuka Y Division of Neonatology, Center for Maternal-Fetal and Neonatal Medicine, National Center for Child Health and - - 2014
Many neonatal intensive care and maternal units still use self-monitoring of blood glucose (SMBG) devices as a tool to aid diagnosis despite the introduction of point-of-care testing (POCT) devices, which are known to have higher accuracy. We evaluated the performance of two glucose meters, the StatStrip (Nova Biomedical), a POCT ...
Van Hirtum Annemie A GIPSA-Lab, UMR CNRS 5216, Grenoble University, 11 rue des Mathématiques (BP46), 38402 Grenoble, - - 2014
Sibilant fricative sound production depends on the geometric and flow properties of the production system. Nevertheless, few studies deal with the potential impact of flow properties other than the inlet volume flow rate on the noise produced. In this work, an experimental study is presented using a replica based on ...
Wei Fang F Key Laboratory of Biology and Genetic Resources of Rubber Tree, Ministry of Agriculture, Rubber Research Institute, Chinese Academy of Tropical Agricultural Sciences, Danzhou, Hainan 571737, China. Electronic address: - - 2014
The rubber tree, Hevea brasiliensis, is a major commercial source of natural rubber. Increasing the rubber yield of rubber trees is a very serious problem since the demands for high quality rubber materials are great. Establishment of a tapping system is based on an estimate of tapping intensity from the ...
Davis Jeffrey M JM Department of Chemical Engineering, University of Massachusetts, Amherst, MA, 01003, USA, - - 2014
Under the approximation that blood behaves as a continuum, a numerical implementation is presented to analyze the linear stability of capillary blood flow through model tree and honeycomb networks that are based on the microvascular structures of biological tissues. The tree network is comprised of a cascade of diverging bifurcations, ...
Doi Kentaro - - 2014
In recent years, the control of ionic currents has come to be recognized as one of the most important issues related to the efficient transport of single molecules and microparticles in aqueous solutions. However, the complicated liquid flows that are usually induced by applying electric potentials have made it difficult ...
Gadda Giacomo G University of Ferrara - - 2014
We developed a mathematical model of the cerebral venous outflow for the simulation of the average blood flows and pressures in the main drainage vessels of the brain. The main features of the model are that it includes a validated model for the simulation of the intracranial circulation, and it ...
Dobson Matthew M Department of Mathematics and Statistics, 710 N. Pleasant Street, University of Massachusetts, Amherst, Massachusetts 01003-9305, - - 2014
This work presents a generalization of the Kraynik-Reinelt (KR) boundary conditions for nonequilibrium molecular dynamics simulations. In the simulation of steady, homogeneous flows with periodic boundary conditions, the simulation box deforms with the flow, and it is possible for image particles to become arbitrarily close, causing a breakdown in the ...
Bachand Philip A M PA Bachand & Associates, 509D Fourth Street, Davis, California 94549, United - - 2014
The agriculturally productive San Joaquin Valley faces two severe hydrologic issues: persistent groundwater overdraft and flooding risks. Capturing flood flows for groundwater recharge could help address both of these issues, yet flood flow frequency, duration, and magnitude vary greatly as upstream reservoir releases are affected by snowpack, precipitation type, reservoir ...
Ochs Christopher J CJ Department of Bioengineering and Therapeutic Sciences, California Institute for Quantitative Biosciences, University of California San Francisco, San Francisco, California, USA. - - 2014
Single-layer membrane valves are simple to fabricate and to integrate into microfluidic devices. However, due to their rectangular flow channel geometry, they do not fully seal. Here, we show that liquid flow can be reduced by over 3 orders of magnitude, enabling the contents of forming droplets to be dynamically ...
Kral Ulrich U Vienna University of Technology, Institute for Water Quality, Resource and Waste Management, Karlsplatz 13/226, A-1040 Vienna, - - 2014
Besides recyclables, the use of materials inevitably yields non-recyclable materials such as emissions and wastes for disposal. These flows must be directed to sinks in a way that no adverse effects arise for humans and the environment. The objective of this paper is to present a new indicator for the ...
Besic Nikola - - 2014
In this paper, we propose a novel ultrasonic tomography method for pipeline flow field imaging, based on the Zernike polynomial series. Having intrusive multipath time-offlight ultrasonic measurements (difference in flight time and speed of ultrasound) at the input, we provide at the output tomograms of the fluid velocity components (axial, ...
Rorrer Nicholas A NA Department of Chemical and Biological Engineering, Colorado School of Mines, 1500 Illinois Street, Golden, Colorado 80401, - - 2014
The first ever molecular-scale simulation of cross-flow migration effects in dense polymer melts is presented; simulations for both unentangled and entangled chains are presented. At quiescence a small depletion next to the wall for the segmental densities of longer chains is present, a corresponding excess exists about one-half a radii ...
Guo Tianyi T School of Biomedical Engineering, McMaster University, 1280 Main St W, Hamilton, ON, L8S 4L8, Canada; Institute of Microelectronics, Chinese Academy of Science, Beijing, 100029, - - 2014
Counting of E. coli DH5α cell suspensions in phosphate buffered saline is performed using a micro-flow cytometer based on a photonic-microfluidic integrated device. Side-scattered light signals are used to count the E. coli cells. A detection efficiency of 92% is achieved when compared with the expected count from a haemocytometer. ...
Kalász H H Department of Pharmacology and Pharmacotherapy, Semmelweis University, 1089, Budapest, Nagyvárad tér 4, Hungary; Department of Pharmacology and Therapeutics, CMHS, United Arab Emirates University, Al Ain, P.O.Box 17666, United Arab - - 2014
This paper reviews the blood-brain barrier (BBB) penetration of newly developed pyridinium aldoximes. Pyridinium aldoximes are highly charged hydrophilic compounds used in the treatment of subjects exposed to organophosphonates because they are effective as acetylcholinesterase reactivators. Pyridinium aldoximes have antidotal effects against poisoning with cholinesterase inhibitors, a frequent problem affecting ...
Pihl Michael - - 2014
The 3-D transverse oscillation method is investigated by estimating 3-D velocities in an experimental flow-rig system. Measurements of the synthesized transverse oscillating fields are presented as well. The method employs a 2-D transducer; decouples the velocity estimation; and estimates the axial, transverse, and elevation velocity components simultaneously. Data are acquired ...
- - 2014
Essential facts Varicose veins are dilated, often palpable subcutaneous veins with reversed blood flow. Most commonly found in the legs, they are estimated to affect at least one third of the adult population. While for many people varicose veins do not present a serious health problem, for others they cause ...
Hupert Mateusz L ML Department of Biomedical Engineering, University of North Carolina, Chapel Hill, NC, USA ; BioFluidica, Inc., Chapel Hill, NC, - - 2014
Microsystem-based technologies are providing new opportunities in the area of in vitro diagnostics due to their ability to provide process automation enabling point-of-care operation. As an example, microsystems used for the isolation and analysis of circulating tumor cells (CTCs) from complex, heterogeneous samples in an automated fashion with improved recoveries ...
Venditti Jeremy G JG Department of Geography, Simon Fraser University, Burnaby, British Columbia V5A 1S6, - - 2014
Bedrock erosion in rivers sets the pace of landscape evolution, influences the evolution of orogens and determines the size, shape and relief of mountains. A variety of models link fluid flow and sediment transport processes to bedrock incision in canyons. The model components that represent sediment transport processes are increasingly ...
Alfadhel A A Computer, Electrical and Mathematical Sciences and Engineering Division (CEMSE), King Abdullah University of Science and Technology (KAUST), Thuwal 23955, Saudi Arabia. - - 2014
A magnetic nanocomposite has been implemented as artificial hair on a giant magnetoimpedance (GMI) thin-film sensor for flow sensing. The 500 μm long and 100 μm in diameter pillars are composed of iron nanowires incorporated in polydimethylsiloxane (PDMS). The nanowires' length and diameter are 6 μm and 35 nm, respectively. ...
Seriani Robson R Centro de Aquicultura, Instituto de Pesca, Avenida Francisco Matarazzo, 455, São Paulo, SP, 05001-900, Brazil, - - 2014
Fish bioassays are valuable tools that can be used to elucidate the toxicological potential of numerous substances that are present in the aquatic environment. In this study, we assessed the antagonistic action of selenium (Se) against the toxicity of mercury (Hg) in fish (Oreochromis niloticus). Six experimental groups with six ...
Schrauben Eric M EM Department of Medical Physics, University of Wisconsin, Madison, Wisconsin, - - 2014
To demonstrate a novel velocity sensitive acquisition and retrospective cardiorespiratory double-gated reconstruction scheme to examine respiratory effect on venous blood flow in healthy volunteers. Radial two dimensional (2D) phase contrast MR is performed at 3 Tesla in the internal jugular vein (IJV) of healthy volunteers (n = 6). Data are retrospectively partitioned ...
MartonĨíková Marcela M Institute of Neurobiology, Slovak Academy of Sciences, Šoltésovej 4, 040 01 Košice, Slovak Republic. - - 2014
New neurons are continuously being added to the olfactory bulb (OB) of adult rodents that are generated in the subventricular zone (SVZ), distant by a few millimeters. Neuronal precursors have to overcome this long distance without the radial-glial migratory scaffold, in contrast to migration mode during embryonic development. The previous ...
Aouane Othmane O Department of Experimental Physics, Saarland University, 66123 Saarbrücken, Germany and Université Grenoble Alpes, LIPHY, F-38000 Grenoble, France and LMPHE, URAC 12, Faculté des Sciences, Université Mohammed V-Agdal, Rabat, - - 2014
Red blood cells (RBCs) are the major component of blood, and the flow of blood is dictated by that of RBCs. We employ vesicles, which consist of closed bilayer membranes enclosing a fluid, as a model system to study the behavior of RBCs under a confined Poiseuille flow. We extensively ...
Tzeng Yu-Chieh YC University of Otago, Wellington - - 2014
Cerebral blood flow responses to transient blood pressure challenges are frequently attributed to cerebral autoregulation (CA) yet accumulating evidence indicates vascular properties like compliance are also influential. We hypothesized that middle cerebral blood velocity (MCAv) dynamics during or following a transient blood pressure perturbation can be accurately explained by the ...
Wang Xiaofei X a Sorbonne Universités , UPMC Univ Paris 6, UMR 7190, Institut Jean le Rond d'Alembert, Paris , - - 2014
A reliable and fast numerical scheme is crucial for the 1D simulation of blood flow in compliant vessels. In this paper, a 1D blood flow model is incorporated with a Kelvin-Voigt viscoelastic arterial wall. This leads to a nonlinear hyperbolic-parabolic system, which is then solved with four numerical schemes, namely: ...
Collard Keith James KJ Keith James Collard, Peninsula Allied Health Centre, School of Health Professions, Faculty of Health and Human Sciences, University of Plymouth, Plymouth, PL6 8BH, United - - 2014
Many premature babies, especially those with a low birth weight are given multiple transfusions during their first few weeks of life. The major serious complications of prematurity include bronchopulmonary dysplasia, with lesser incidences of retinopathy of prematurity, intraventricular haemorrhage, and necrotising enterocolitis. Many studies have shown correlations between the receipt ...
Oren Liran L Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati, Cincinnati, Ohio, - - 2014
During phonation, skewing of the glottal flow waveform (Q) refers to a phenomenon that occurs when the flow decelerates more rapidly than it accelerates. This skewing is clinically important because it increases the glottal efficiency, which is defined by the acoustic intensity (sound pressure level) divided by the subglottal pressure. ...
Felderhof B U BU Institut für Theorie der Statistischen Physik, RWTH Aachen University, Templergraben 55, 52056 Aachen, - - 2014
Swimming velocity and rate of dissipation of a sphere with surface distortions are discussed on the basis of the Stokes equations of low-Reynolds-number hydrodynamics. At first the surface distortions are assumed to cause an irrotational axisymmetric flow pattern. The efficiency of swimming is optimized within this class of flows. Subsequently, ...
Kunte Amit A Chemical Engineering Division, National Chemical Laboratory, Pune 411008, - - 2014
We show that the flow of granular material inside a two-dimensional flat bottomed hopper is altered significantly by having more than one exit orifice. For hoppers with small orifice widths, intermittent flow through one orifice enables the resumption of flow through the adjacent jammed orifice, thus displaying a sequence of ...
Gusmão Luiz Carlos Buarque LC Federal University of - - 2014
The objective is to reinforce the importance of blood reinfusion as a cheap, safe and simple method, which can be used in small hospitals, especially those in which there is no blood bank. Moreover, even with the use of devices that perform the collection and filtration of blood, more recent ...
Meattey Dustin E DE Biodiversity Research Institute, 652 Main Street, Gorham, ME 04038, United States. Electronic address: - - 2014
In North America and Europe, sea ducks are important indicators of ecological health and inshore marine pollution. To explore spatial variation in mercury accumulation in common eiders in the northeastern United States, we compared concentrations of total mercury in common eider blood at several New England locations between 1998 and ...
De Kesel Pieter M M PM Laboratory of Toxicology, Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Harelbekestraat 72, 9000, Ghent, - - 2014
Dried blood spot (DBS) sampling has gained wide interest in bioanalysis during the last decade and has already been successfully applied in pharmacokinetic and phenotyping studies. However, all of the available phenotyping studies used small datasets and did not include a systematic evaluation of DBS-specific parameters. The latter is important ...
Dubois Wil - - 2014
To measure the concentration of glucose in your blood, you put a strip in the meter, poke a hole in your finger to get a sample of blood, touch the tip of the test strip to the drop of blood, and wait for the result. It sounds pretty straightforward. But, ...
Assemat P P Department of Mechanical and Aerospace Engineering, Division of Biological Engineering, Monash University, Victoria 3800, - - 2014
Atherosclerotic plaques develop at particular sites in the arterial tree, and this regional localisation depends largely on haemodynamic parameters (such as wall shear stress; WSS) as described in the literature. Plaque rupture can result in heart attack or stroke and hence understanding the development and vulnerability of atherosclerotic plaques is ...
Kang Yang Jun YJ Department of Mechanical Engineering, Chosun University , Gwangju, South - - 2014
This study suggests a new erythrocyte sedimentation rate (ESR) measurement method for the biophysical assessment of blood by using a microfluidic device. For an effective ESR measurement, a disposable syringe filled with blood is turned upside down and aligned at 180° with respect to gravitational direction. When the blood sample ...
Wang Hsien-Yi - - 2014
Hemodialysis is the most common treatment for patients with end-stage renal disease. For hemodialysis, consistently functional vascular access must be surgically created with an anastomosis of artery and vein, referred to as an arteriovenous fistula (AVF). However, AVF dysfunction may occur over time. Angiography and Doppler ultrasound are usually used ...
Chan Aaron - - 2014
Recent hardware advances in optical coherence tomography (OCT) have led to ever higher A-scan rates. However, the estimation of blood flow axial velocities is limited by the presence and type of noise. Higher acquisition rates alone do not necessarily enable precise quantification of Doppler velocities, particularly if the estimator is ...
France Christopher R CR Department of Psychology, Ohio University, Athens, - - 2014
Evidence indicates that donor identity is an important predictor of donation behavior; however, prior studies have relied on diverse, unidimensional measures with limited psychometric support. The goals of this study were to examine the application of self-determination theory to blood donor motivations and to develop and validate a related multidimensional ...
Ong Frank F Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, California, - - 2014
To investigate four-dimensional flow denoising using the divergence-free wavelet (DFW) transform and compare its performance with existing techniques. DFW is a vector-wavelet that provides a sparse representation of flow in a generally divergence-free field and can be used to enforce "soft" divergence-free conditions when discretization and partial voluming result in ...
Oren Liran L Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati, 231 Albert Sabin Way, Cincinnati, Ohio - - 2014
Previous flow velocity measurements during phonation in canine larynges were done above the glottal exit. These studies found that vortical structures are present in the flow above the glottis at different phases of the glottal cycle. Some vortices were observed to leave the glottis during the closing phase and assumptions ...
Crimmins Eileen E a Davis School of Gerontology , University of Southern California , Los Angeles , California , - - 2014
Assessment of health in large population studies has increasingly incorporated measures of blood-based biomarkers based on the use of dried blood spots (DBS). The validity of DBS assessments made by labs used by large studies is addressed by comparing assay values from DBS collected using conditions similar to those used ...
Schudt Florian F Technische Hochschule Mittelhessen - University of Applied Sciences, Giessen, - - 2014
The respiratory flow is a good indicator of sleep-related breathing disorders. Common praxis is to use a pneumotachograph as the golden standard for flow measurement. However, it does not have to be necessarily the best possible test device for long-term condition, because the device is very uncomfortable and rarely suitable ...
Kumar Shailendra S Department of Surgery, King George's Medical University, Lucknow, Uttar Pradesh, - - 2014
Venous malformations (VMs) are slow-flow vascular malformations, caused by abnormalities in the development of the veins. Venous malformations vary in size and location within the body. When the skin or tissues just under the skin are affected, they appear as slightly blue-colored skin stains or swellings. These can vary in ...
Fitts Michelle K MK Department of Bioengineering, University of Utah, Salt Lake City, Utah, - - 2014
Surgically-created blood conduits used for chronic hemodialysis, including native arteriovenous fistulas (AVFs) and synthetic AV grafts (AVGs), are the lifeline for kidney failure patients. Unfortunately, each has its own limitations: AVFs often fail to mature to become useful for dialysis and AVGs often fail due to stenosis as a result ...
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