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De Kesel Pieter M M PM Laboratory of Toxicology, Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Harelbekestraat 72, 9000, Ghent, - - 2014
Dried blood spot (DBS) sampling has gained wide interest in bioanalysis during the last decade and has already been successfully applied in pharmacokinetic and phenotyping studies. However, all of the available phenotyping studies used small datasets and did not include a systematic evaluation of DBS-specific parameters. The latter is important ...
Wang Hsien-Yi - - 2014
Hemodialysis is the most common treatment for patients with end-stage renal disease. For hemodialysis, consistently functional vascular access must be surgically created with an anastomosis of artery and vein, referred to as an arteriovenous fistula (AVF). However, AVF dysfunction may occur over time. Angiography and Doppler ultrasound are usually used ...
Chan Aaron - - 2014
Recent hardware advances in optical coherence tomography (OCT) have led to ever higher A-scan rates. However, the estimation of blood flow axial velocities is limited by the presence and type of noise. Higher acquisition rates alone do not necessarily enable precise quantification of Doppler velocities, particularly if the estimator is ...
France Christopher R CR Department of Psychology, Ohio University, Athens, - - 2014
Evidence indicates that donor identity is an important predictor of donation behavior; however, prior studies have relied on diverse, unidimensional measures with limited psychometric support. The goals of this study were to examine the application of self-determination theory to blood donor motivations and to develop and validate a related multidimensional ...
Ong Frank F Department of Electrical Engineering and Computer Sciences, University of California, Berkeley, California, - - 2014
To investigate four-dimensional flow denoising using the divergence-free wavelet (DFW) transform and compare its performance with existing techniques. DFW is a vector-wavelet that provides a sparse representation of flow in a generally divergence-free field and can be used to enforce "soft" divergence-free conditions when discretization and partial voluming result in ...
Oren Liran L Department of Otolaryngology-Head and Neck Surgery, University of Cincinnati, 231 Albert Sabin Way, Cincinnati, Ohio - - 2014
Previous flow velocity measurements during phonation in canine larynges were done above the glottal exit. These studies found that vortical structures are present in the flow above the glottis at different phases of the glottal cycle. Some vortices were observed to leave the glottis during the closing phase and assumptions ...
Crimmins Eileen E a Davis School of Gerontology , University of Southern California , Los Angeles , California , - - 2014
Assessment of health in large population studies has increasingly incorporated measures of blood-based biomarkers based on the use of dried blood spots (DBS). The validity of DBS assessments made by labs used by large studies is addressed by comparing assay values from DBS collected using conditions similar to those used ...
Schudt Florian F Technische Hochschule Mittelhessen - University of Applied Sciences, Giessen, - - 2014
The respiratory flow is a good indicator of sleep-related breathing disorders. Common praxis is to use a pneumotachograph as the golden standard for flow measurement. However, it does not have to be necessarily the best possible test device for long-term condition, because the device is very uncomfortable and rarely suitable ...
Tuziuti Toru T National Institute of Advanced Industrial Science and Technology (AIST), Nagoya 463-8560, Japan. Electronic address: - - 2013
We measured longitudinal speed of sound for matrix[poly(lactic acid)]-additive(clay particles) composite rectangular-solid specimen prepared by injection molding. It was found that the speed of sound measured in the direction along the longer side of the specimen was the highest at the middle of the specimen. This trend corresponded with that ...
Nozaki K - - 2013
The sibilant /s/ is produced by raising the tongue against the roof of the mouth to form a narrow constriction, which is adjusted so that the airstream emerging from it impinges on the incisors. However, the location where the sibilant sound occurs is unclear, as are the details of the ...
Reif Roberto R University of Washington, Department of Bioengineering, Seattle, WA 98195, - - 2013
In this work we determined the contributions of loud sound exposure (LSE) on cochlear blood flow (CoBF) in an in vivo anesthetized mouse model. A broadband noise system (20 kHz bandwidth) with an intensity of 119 dB SPL, was used for a period of one hour to produce a loud ...
Kniesburges Stefan - - 2013
Within the fully coupled multiphysics phonation process, the fluid flow plays an important role for sound production. This study addresses phenomena in the flow downstream of synthetic self-oscillating vocal folds. An experimental setup consisting of devices for producing and conditioning the flow including the main test channel was applied. The ...
Timmerman Philip - - 2013
The European Bioanalysis Forum dried blood spots/microsampling consortium is reporting back from the experiments they performed on further documenting the potential hurdles of the DBS technology. Their experiments focused on the impact of hematocrit changes, IS addition, spot homogeneity, aging of spots and stability of fresh blood and cards. Results ...
de Vries Ronald - - 2013
Background: The European Bioanalysis Forum dried blood spots (DBS)/microsampling consortium is reporting back from the experiments they performed on further documenting the potential hurdles of the DBS technology. This paper is focused on the impact of hematocrit changes on DBS analyses. Results: The hematocrit can have an effect on the ...
Seo Jung Hee JH Johns Hopkins University, Baltimore, MD 21218, - - 2013
A multiphysics simulation approach is developed for predicting cardiac flows as well as for conducting virtual echocardiography (ECHO) and phonocardiography (PC) of those flows. Intraventricular blood flow in pathological heart conditions is simulated by solving the three-dimensional incompressible Navier-Stokes equations with an immersed boundary method, and using this computational hemodynamic ...
Tze Wei Chu Derek - - 2013
The technique presented here uses an impedance head to measure the input impedance spectrum of a physical model of a vocal tract, and then to inject a known glottal flow waveform into the tract. The sound measured outside the mouth is used to evaluate inverse filtering techniques by comparison with ...
Smith Simeon L - - 2013
The effect of subglottic stenosis on vocal fold vibration is investigated. An idealized stenosis is defined, parameterized, and incorporated into a two-dimensional, fully-coupled finite element model of the vocal folds and laryngeal airway. Flow-induced responses of the vocal fold model to varying severities of stenosis are compared. The model vibration ...
Klopsch Christian C Department of Neurobiology, University of Vienna, Vienna, Austria. - - 2013
When hungry, the wandering spider Cupiennius salei is frequently seen to catch flying insect prey. The success of its remarkable prey-capture jump from its sitting plant into the air obviously depends on proper timing and sensory guidance. In this study, it is shown that particular features of the airflow generated ...
Yu Lu - - 2013
BACKGROUND:: Undetected apnea can lead to severe hypoxia, bradycardia, and cardiac arrest. Tracheal sounds entropy has been proved to be a robust method for estimating respiratory flow, thus maybe a more reliable way to detect obstructive and central apnea during sedation. METHODS:: A secondary analysis of a previous pharmacodynamics study ...
Hammer Michael J - - 2013
Phonatory onset is important for speech and voice and may be substantially impaired in people with Parkinson's Disease (PD). However, the physiologic contributions of laryngeal and respiratory control to phonatory onset in PD are not well understood. Acoustic measurement of phonatory onset in neurological disease has been limited due to ...
Dai Xiwen - - 2012
In this paper, a theoretical model is developed to study the acoustical response of a Helmholtz resonator as a duct-branched acoustic absorber subjected to both high-intensity sound and grazing flow. The present model is comprised of a discrete vortex model in combination with a one-dimensional duct sound propagation model. The ...
Zhao Jing - - 2012
BACKGROUND AND AIMS: Disturbances of microcirculation and hemorheological changes in the inner ear are the results of noise-induced hearing loss (NIHL). Both the disturbances of microcirculation and hemorheological changes are the etiologies of NIHL development, but they are also the results. Although previous reports that inhalation of high concentration of ...
Nilsson Anders - - 2012
PURPOSE: To evaluate accuracy and noise properties of a novel time-resolved, three-dimensional, three-directional phase contrast sequence with variable velocity encoding (denoted 4D-vPC) on a 3 Tesla MR system, and to investigate potential benefits and limitations of variable velocity encoding with respect to depicting blood flow patterns. MATERIALS AND METHODS: A ...
Guzmán-Lastra Francisca - - 2012
Self-propelled microorganisms, such as unicellular algae or bacteria, swim along their director relative to the fluid velocity. Under a steady shear flow the director rotates in close orbit, a periodic structure that is preserved under an oscillatory shear flow. If the shear flow is subjected to small fluctuations produced by ...
Jing Xiaodong - - 2012
This paper addresses the problem how to measure acoustic impedance of microperforation panels (MPPs) under flow conditions. Since 1960s, many different methods have been proposed to tackle this problem, mainly motivated by the aim of reducing noise emission from aeroengines, ventilators and other fluid machines. It has been found that ...
Xu Yaoqiang - - 2012
ABSTRACT Background: Hypoperfusion of the pulmonary vascular bed under the condition of congenital cardiac malformations may lead to progressive pulmonary vascular disease. To improve the mechanistic understanding of this disease, we examined the biochemical and morphological changes of the lung in a relevant animal model and provided valuable insights into ...
Dehner Rick - - 2012
Broadband noise, accompanying the flow separation and turbulence, is studied for an automotive centrifugal compressor on a steady-flow turbocharger bench facility. When operated in the mid-flow region, the current compressor exhibited elevated broadband noise at high frequencies, which was evident both in the upstream compressor duct and external sound pressure ...
Zhang Yingze Y Division of Pulmonary, Allergy and Critical Care Medicine, Dorothy P. and Richard P. Simmons Center for Interstitial Lung Disease, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, - - 2012
This review examines the recent literature on molecular biomarkers of idiopathic pulmonary fibrosis (IPF). Specific attention is dedicated to the recent studies that identified the genes associated with IPF and the peripheral blood biomarkers that predict outcome in IPF. Multiple studies attempted to identify diagnostic and predictive biomarkers in IPF. ...
Ivanenko Natalya B - - 2012
Determination of aluminum (Al), beryllium (Be), cadmium (Cd), chromium (Cr), mercury (Hg), manganese (Mn), nickel (Ni), lead (Pb), and thallium (Tl) concentrations in human blood using high-frequency modulation polarization Zeeman graphite furnace atomic absorption spectrometry (GFAAS) was performed. No sample digestion was used in the current study. Blood samples were ...
Robbins Anthony - - 2012
When the US Centers for Disease Control met a hard wall of political restraint in attempting a full response to the emergency of AIDS in the early 1980s, it was possible to move toward protection of blood and blood products from the legislative branch of government instead - despite resistance ...
Meesters Roland Jw - - 2012
Background: The hematocrit effect is a hurdle for successful introduction of the dried blood spot (DBS) in a regulated environment. Recently, attempts were taken to overcome the hematocrit effect by whole-cut DBS analysis. This paper presents the next-generation whole-cut DBS; dried matrix on paper disks (DMPD). Results: DMPD eliminated the ...
Yang Ling - - 2012
Morbidity from allergic diseases is increasing. Basophils play a critical role in systemic anaphylaxis and chronic allergic inflammation. The prenatal environment must be regarded as a possible early risk factor for allergic diseases in children. Our objective was to determine if basophils harvested from neonates genetically predisposed to atopic disease ...
Nogueira R B - - 2012
Systemic vascular impedance represents the retrograde strength of the blood flow to the left ventricle, thus it is one of the main compounds of afterload. Mitral regurgitation is markedly sensitive to afterload alterations. The purpose of this study was to evaluate muscular arterial impedance in dogs with chronic degenerative mitral ...
Uhl J-F - - 2012
The aim of this paper is to demonstrate the location of the venous foot pump using an anatomical study. Four hundred cadaveric feet were injected with green neoprene latex followed by a dissection. A coloured segmentation of the venous system was achieved. The Lejars' concept of the venous sole of ...
Bonnin Philippe - - 2012
BACKGROUND AND AIMS: Active Crohn's disease affects intestine but may alter other locations as eyes vasculature. Previous studies provide evidence of elevated blood flow velocities (BFv) and volume (BFV) in superior mesenteric artery (SMA). We prospectively studied hemodynamics in feeding arteries of bowel and eyes before and 2weeks after treatment ...
Noizat-Pirenne F - - 2012
Transfusion remains a key treatment in sickle cell disease. The occurrence of a delayed haemolytic transfusion reaction is not rare and is a life-threatening event. The main cause of delayed haemolytic transfusion reaction is production of alloantibodies against red blood cell antigens. The high rate of alloimmunization in sickle cell ...
Bird James - - 2012
Transfusion of large amounts of blood products is a complex and changing practice. British and American military experience of the process in Afghanistan and Iraq, and the findings of the international CRASH 2 study (Shakur et al 2010), have led to changes in practice (Moor et al 2009). The procedure ...
Jeong Woo Kyoung - - 2012
Objectives- The purpose of this study was to categorize hepatofugal portal venous flow on Doppler sonography after liver transplantation and to investigate its clinical importance and presumed causes based on radiologic and pathologic findings. Methods- This retrospective study was approved by our Institutional Review Board, and the requirement for informed ...
Fast Loren D - - 2012
The transfusion of blood products can result in a variety of consequences, including transfer of pathogens and the induction of immune responses, such as the almost invariably fatal transfusion-associated graft-versus-host disease (TA-GVHD). Exposure of blood products to γ-irradiation is currently the standard of care for the prevention of TA-GVHD. Regulatory, ...
Tanhehco Yvette C - - 2012
Prior to the introduction of recombinant human erythropoietin (EPO), red blood cell (RBC) transfusions were frequently required when iron and anabolic steroids failed to improve the clinical symptoms of anemia associated with hemoglobin (Hb) levels that were commonly less than 7 g/dl. After the approval of EPO in the United ...
Owusu Benjamin Y - - 2012
Nitric oxide (NO) is a key modulator of vascular homeostasis controlling critical functions related to blood flow, respiration, cell death and proliferation, and protecting the vasculature from pro-inflammatory and coagulative stresses. Inhibition of NO formation, and/or diversion of NO away from its physiological signalling targets lead to dysregulated NO bioavailability, ...
Dake Michael D - - 2012
Multiple sclerosis (MS) is a chronic inflammatory disorder of the central nervous system (CNS) most commonly characterized by focal areas of myelin destruction, inflammation and axonal transection. The multicentric inflammation and demyelination of the brain and spinal cord are associated with variable neurologic symptoms ranging from mild dysfunction to debilitating. ...
Imrie Meghan N - - 2012
COMMENTARY ON: Long TR, Stans AA, Shaughnessy WJ, et al. Changes in red blood cell transfusion practice during the past quarter century: a retrospective analysis of pediatric patients undergoing elective scoliosis surgery using the Mayo database. Spine J 2012;12:455-62 (in this issue).
Sato Kota - - 2012
OBJECTIVE: To assess cerebrospinal fluid (CSF) flow dynamics involvement in the pathogenesis of amyotrophic lateral sclerosis (ALS), we conducted CSF flow studies on 40 individuals with motor neuron diseases (MNDs) including ALS, and 28 age-matched normal and disease [cervical spondylosis (CS)] controls. METHODS: The CSF pulsatile velocity anterior to the ...
Alhumaidan Hiba - - 2012
BACKGROUND: Human granulocytic anaplasmosis (HGA) is a tick-borne rickettsial infectious disease. To date four cases of transfusion-transmitted anaplasmosis (TTA) have been described in the literature, and only one from leukoreduced red blood cells (RBCs). CASE REPORT: A 64-year-old patient with acute gastrointestinal blood loss was admitted to the hospital and ...
Narita Mitsuo - - 2012
To the Editor, we read with great interest the article by Chung et al. which appeared recently in the journal. In that paper the authors reported that the decreased IL-18 response in severe pneumonia group vs. non-severe group was observed regardless of asthma status of the patients, whose findings were ...
Yazdanbakhsh Karina - - 2012
Red blood cell transfusions have reduced morbidity and mortality for patients with sickle cell disease. Transfusions can lead to erythrocyte alloimmunization, however, with serious complications for the patient including life-threatening delayed hemolytic transfusion reactions and difficulty in finding compatible units, which can cause transfusion delays. In this review, we discuss ...
Sato Ana Claudia - - 2012
Passion fruit (Passiflora edulis Sims f. flavicarpa) is popularly known for its sedative and calming properties and is consumed as a fresh fruit or as a juice. The clinical observation of blood incoagulability associated with excessive consumption of passion fruit juice, in a patient treated with warfarin, prompted the current ...
Chmelar Jindrich J Division of Vascular Inflammation, Diabetes and Kidney, Department of Medicine and Institute of Physiology, Technical University Dresden, 01307 Dresden, - - 2012
Ticks are mostly obligatory blood feeding ectoparasites that have an impact on human and animal health. In addition to direct damage due to feeding, some tick species serve as the vectors for the causative agents of several diseases, such as the spirochetes of the genus Borrelia causing Lyme disease, the ...
Kim Jihyun - - 2012
Melorheostosis is a rare disorder characterized by irregular, flowing hyperostosis in long bones, commonly described on radiographs as wax flowing down a candle. In addition to bony sclerosis, cutaneous manifestations overlying the involved bones have been reported including linear scleroderma, neurofibromatosis, and vascular and lymphatic malformations. Unilateral nevoid telangiectasia (UNT) ...
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