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Davitashvili D - - 2012
Present research aimed at investigation of the role of several inflammatory cytokines and free toxic radicals in Multiple Sclerosis (MS) course and disability progression as well as factors that can assist to the early transition of Relapse Remitting MS (RRMS) in Secondary Progressive MS (SPMS). Totally 22 MS patients, 14 ...
Roiz David - - 2012
Surveillance, research, and control of mosquito-borne diseases such as West Nile virus require efficient methods for sampling mosquitoes. We compared the efficacy of BG-Sentinel and Centers for Disease Control and Prevention (CDC)-CO(2) traps in terms of the abundances of host-seeking and blood-fed female mosquitoes and the origin of mosquito bloodmeals. ...
La Raja Massimo - - 2012
The incidental finding of monoclonal immunoglobulin in the sera of healthy blood donors is a relatively frequent event and in such cases the subjects are commonly deferred permanently from donating blood. However, no follow-up studies of these cases have been published so far. Since 2000, all regular blood donors at ...
Gladwin Mark T - - 2012
Blood transfusion represents the first and most prescribed cell-based therapy; however, clinical safety and efficacy trials are lacking. Clinical cohort studies have suggested that massive transfusion and/or transfusion of aged stored blood may contribute to multiorgan dysfunction in susceptible patients. In this issue of the JCI, Baek and colleagues report ...
Uçeyler Nurcan - - 2012
Objectives- The purpose of this study was to investigate cervical and cerebral blood flow characteristics in patients with Fabry disease at baseline and under enzyme replacement therapy. Methods- In this case-control study we prospectively studied 68 patients with Fabry disease with extracranial and transcranial Doppler sonography. We compared extracranial and ...
Phair Kristen A - - 2012
An 8-yr-old, captive, spayed, female maned wolf (Chrysocyon brachyurus) developed progressive lethargy and weakness over a 24-hr period. Clinical signs included vomiting, recumbency, horizontal nystagmus, possible blindness, pale icteric mucus membranes, and port-wine colored urine. A complete blood cell count revealed severe anemia (packed cell volume [PCV], 6%) and intraerythrocytic ...
Akinosoglou Karolina S - - 2012
Plasmodium falciparum malaria remains a major cause of mortality throughout the tropical world. Haematological abnormalities are considered a hallmark of malaria, bearing an impact on final outcome and representing indices of prognostic and follow-up value. These include severe anaemia, coagulation disturbances, leukocyte numerical or functional changes and spleen involvement. Anaemia ...
Risso Francesco - - 2012
Abstract The present overview is aimed at reporting the standard primary investigations that are mandatory in preterm and term newborns at admission to neonatal unit in the first hours after birth. Herein, the main neonatal screening tests for early detection of metabolic diseases are described as well as laboratory standard ...
Freitas José Cláudio Carneiro de - - 2012
Canine visceral leishmaniasis (CVL) is a zoonotic disease with different clinical manifestations. Parasitism often occurs in bone marrow, but changes have been observed in peripheral blood and serum biochemical parameters. The aim of this study was to evaluate the hematological and biochemical parameters in dogs naturally infected by Leishmania chagasi. ...
Calzetta Esteban - - 2012
We analyze a possible extension of Gioia and Chakraborty's momentum transfer model of friction in steady turbulent pipe flows [Phys. Rev. Lett. 96, 044502 (2006)] to the case of time- and/or space-dependent turbulent flows. The end result is an expression for the stress at the wall as the sum of ...
Triozzi Pierre L - - 2012
Uveal melanoma disseminates hematogenously, and blood biomarkers may be useful for prognosis and for monitoring disease progression. Melanoma-associated, metastatic and immune factors have been measured in the blood of patients with uveal melanoma, as have circulating melanoma cells. Most of the biomarkers were derived from studies in cutaneous melanoma. For ...
Murphy Matthew J - - 2012
Abstract We wished to longitudinally assess early changes in cerebral perfusion (CP) and its relationship to cognitive impairment (CI) in ALS. Fourteen ALS patients at time of diagnosis and 11 spousal controls, both without CI, were longitudinally assessed to determine a relationship between CP and incidence of CI in early ...
Ono Hirohisa - - 2012
We have treated 4 patients of acute erythematous skin diseases with fever and/or pain by H2 enriched intravenous fluid. We also added data from two volunteers for assessing the mode of H2 delivery to the skin for evaluation of feasibility of H2 treatment for this type of skin diseases. All ...
Giovannetti Antonello - - 2012
Aims: The aim of this work was to investigate whether systemic oxidative imbalance that occurs in patients with systemic sclerosis affects red blood cell integrity. Methods: Reactive oxygen species, intracellular content of total thiols and molecules involved in red blood cell aging (e.g., glycophorin A, band 3, CD47 and phosphatidylserine ...
Mansueto Pasquale - - 2012
Cobalamin (vitamin B(12)) deficiency occurs with several disorders, involving different organs and systems, including blood, bowel, nervous system and eyes. Although the most important features are usually haematological ones, presence of neurological involvement, in the absence of blood count alterations, has just been described in the literature. Here we report ...
Yakut Zeynep Ilerisoy - - 2012
Purpose: To evaluate ocular blood flow dynamics by color Doppler ultrasonography (CDU) in patients with end-stage renal disease (ESRD). Additionally, to investigate the effect of dialysis type on ocular blood flow by comparing the findings of peritoneal dialysis (PD) subjects, hemodialysis (HD) subjects, and healthy controls. Material and methods: Forty ...
Sands Gh - - 2012
Chronic use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with an increased risk of gastrointestinal (GI) toxicity, including occult blood loss and the development of clinically significant anemia. The aim of this study was to investigate the clinical importance of clinically significant anemia/blood loss. Pooled analysis of 51 blinded, controlled ...
Walkden Deborah - - 2012
To determine venesection patterns in hereditary haemochromatosis (HC) patients in Christchurch, New Zealand, their contribution to the blood supply, and reasons for deferral. Review of clinical records of 412 HC patients venesected by the NZ Blood Service at least once during 2009. Of 275 males and 137 females, 384 had ...
Eshoo Mark W - - 2012
Direct molecular tests in blood for early Lyme disease can be insensitive due to low amount of circulating Borrelia burgdorferi DNA. To address this challenge, we have developed a sensitive strategy to both detect and genotype B. burgdorferi directly from whole blood collected during the initial patient visit. This strategy ...
Zuhur Sayid Shafi - - 2012
To determine the role of peak systolic velocity, end-diastolic velocity and resistance indices of both the right and left inferior thyroid arteries measured by color-flow Doppler ultrasonography for a differential diagnosis between gestational transient thyrotoxicosis and Graves' disease during pregnancy. The right and left inferior thyroid artery-peak systolic velocity, end-diastolic ...
Bannach Oliver - - 2012
Prion diseases are transmissible neurodegenerative diseases affecting humans and animals. The agent of the disease is the prion consisting mainly, if not solely, of a misfolded and aggregated isoform of the host-encoded prion protein (PrP). Transmission of prions can occur naturally but also accidentally, e.g. by blood transfusion, which has ...
Lacroux Caroline - - 2012
The identification in the UK of 4 v-CJD infected patients thought to be due to the use of transfused Red Blood Cell units prepared from blood of donors incubating v-CJD raised major concerns in transfusion medicine. The demonstration of leucocyte associated infectivity using various animal models of TSE infection led ...
Andréoletti Olivier - - 2012
It is now clearly established that the transfusion of blood from variant CJD (v-CJD) infected individuals can transmit the disease. Since the number of asymptomatic infected donors remains unresolved, inter-individual v-CJD transmission through blood and blood derived products is a major public health concern. Current risk assessments for transmission of ...
Qvarnstrom Yvonne - - 2012
The laboratory diagnosis of Chagas disease is challenging because the usefulness of different diagnostic tests will depend on the stage of the disease. Serology is the preferred method for patients in the chronic phase, whereas PCR can be successfully used to diagnose acute and congenital cases. Here we present data ...
Sutherland Jayne S JS Medical Research Council Unit, Atlantic Road, Fajara, The Gambia, West Africa. - - 2012
Pleural TB is notoriously difficult to diagnose due to its paucibacillary nature yet it is the most common cause of pleural effusions in TB endemic countries such as The Gambia. We identified both cellular and soluble biomarkers in the pleural fluid that allowed highly accurate diagnosis of pleural TB compared ...
Pedroso Gabriela L GL Hospital de Clínicas de Porto Alegre, Centro de Pesquisa Experimental Laboratório de Hepatologia e Gastroenterologia Experimental, Porto Alegre, RS, Brasil. - - 2012
The zebrafish has been used as an animal model for studies of several human diseases. It can serve as a powerful preclinical platform for studies of molecular events and therapeutic strategies as well as for evaluating the physiological mechanisms of some pathologies. There are relatively few publications related to adult ...
Zalpuri Saurabh S Sanquin-LUMC Jon J van Rood Center for Clinical Transfusion Research, Leiden, the - - 2012
Individuals exposed to red blood cell alloantigens through transfusion, pregnancy or transplantation may produce antibodies against the alloantigens. Alloantibodies can pose serious clinical problems such as delayed haemolytic reactions and logistic problems, for example, to obtain timely and properly matched transfusion blood for patients in which new alloantibodies are detected. ...
Dake Michael D MD Department of Cardiothoracic Surgery, Standford University School of Medicine, Stanford, CA 94305-5407, USA. - - 2011
Chronic cerebrospinal venous insufficiency (CCSVI) is a term used to describe impaired venous drainage from the central nervous system (CNS) caused by abnormalities in anatomy and flow affecting the extracranial veins. Recently, it has been proposed that CCSVI may contribute to the pathogenesis of multiple sclerosis (MS). It is hypothesized ...
Bernstine Hanna - - 2011
Purpose: To prospectively determine whether fluorine 18 fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) early dynamic blood flow estimates could be used to discriminate hepatocellular carcinoma (HCC) from background liver and to characterize HCC in patients with and those without angioinvasion; and to evaluate the association between blood flow ...
Zhang Zhen-Du - - 2011
Coronary Flow Reserve (CFR) is an important index of coronary microcirculatory function. The objective of this study was to validate the reproducibility and accuracy of intravascular conductance catheter-based method for measurements of baseline and hyperemic coronary flow velocity (and hence CFR). The absolute coronary blood velocity was determined by measuring ...
King Deirdre M - - 2011
Polyvinyl alcohol cryogel (PVA-C) is presented as a vessel-mimicking material for use in anatomically realistic Doppler flow phantoms. Three different batches of 10% wt PVA-C containing (i) PVA-C alone, (ii) PVA-C with antibacterial agent and (iii) PVA-C with silicon carbide particles were produced, each with 1-6 freeze-thaw cycles. The resulting ...
Rice Thomas W - - 2011
The esophagus spans three body cavities and has no mesentery, continually borrowing or sharing vessels, lymphatics, and nerves with associated organs. However, constant along this path is an intricate mural structure. An understanding of the esophageal wall, its blood supply, lymphatic drainage, and innervation is essential for successful esophageal surgery.
Ragan Dustin K - - 2011
To test the ability of a multi-band RF pulse to reduce flow enhancement artifacts for steady state imaging without compromising temporal resolution or spatial coverage. Selectively spoiled composite RF pulses that provide simultaneous excitation and flow preparation were designed and tested by means of simulation, phantom, and in vivo measurements ...
Hyväluoma J - - 2011
On microstructured hydrophobic surfaces, geometrical patterns may lead to the appearance of a superhydrophobic state, where gas bubbles at the surface can have a strong impact on the fluid flow along such surfaces. In particular, they can strongly influence a detected slip at the surface. We present two-phase lattice Boltzmann ...
Nightingale M J - - 2011
Three EBA specified blood bag configurations ('Eurobloodpack') are described which are capable of meeting >80% of its member's requirements. These include a 'top-and-top' and two 'bottom-and-top' packs enabling aseptic, pre-donation collection of up to 40 ml of samples, 427·5-522·5 ml of whole blood and the preparation of an extensive range of blood ...
Krishnan Harinarayan - - 2011
Many flow visualization techniques, especially integration-based methods, are problematic when the measured data exhibits noise and discretization issues. Particularly, this is the case for flow-sensitive phase-contrast magnetic resonance imaging (PC-MRI) datasets which not only record anatomic information but also time-varying flow information. We propose a novel approach for the visualization ...
Huang Her-Hsiung - - 2011
Objectives: The goal of this study was to enhance the blood responses to titanium (Ti) surfaces used for dental implant application through the formation of a TiO(2) nano-mesh surface layer produced by a fast electrochemical anodization treatment. Material and methods: Electrochemical anodization treatments with different anodization currents and temperatures in ...
Koku Harun H Department of Chemical Engineering, University of Delaware, Newark, DE 19716, - - 2011
The flow behavior of a commercial polymeric monolith was investigated by direct numerical simulations employing the lattice-Boltzmann (LB) methodology. An explicit structural representation of the monolith was obtained by serial sectioning of a portion of the monolith and imaging by scanning electron microscopy. After image processing, the three-dimensional structure of ...
Mordant David J - - 2011
To assess the accuracy of human blood oximetry measurements in a model eye with a hyperspectral fundus camera. Seven human whole blood samples (two arterial, five venous) were obtained, the oxygen saturations measured with a CO oximeter, and the samples inserted into quartz tubes with internal diameters of 100 and ...
Xu Ying - - 2011
In this paper, numerical simulations are used to study the turbulent wind noise reduction effect of microphone windscreens with varying shapes and flow resistivities. Typical windscreen shapes consisting of circular, elliptical, and rectangular cylinders are investigated. A turbulent environment is generated by placing a solid circular cylinder upstream of the ...
Markl Michael - - 2011
To systematically investigate the scan-rescan reproducibility and observer variability of flow-sensitive four-dimensional (4D) MRI in the aorta for the assessment of blood flow and global and segmental wall shear stress. ECG and respiration-synchronized flow-sensitive 4D MRI data (spatio-temporal resolution = 1.7 × 2.0 × 2.2 mm(3) /40.8 ms) were acquired ...
Dunning K - - 2011
Abstract Wright-Giemsa staining is a common procedure that is performed routinely in hematology laboratories. Consistency in intra-laboratory staining quality is essential for accurate morphological interpretation of blood smears. Although the Wright-Giemsa stain can be challenging to perform, the methods illustrated here have provided consistent, high quality stains in the Special ...
Roeykens H - - 2011
An early determination of pulpal vitality is crucial with respect to a correct differential diagnosis of revascularisation or necrosis and its treatment. Sensibility tests (cold, heat, electrical pulp test) in combination with radiographs are commonly promoted. However these tests are arbitrary, based on sensations and therefore not always reliable. In ...
Hariharan Prasanna - - 2011
This study is part of a FDA-sponsored project to evaluate the use and limitations of computational fluid dynamics (CFD) in assessing blood flow parameters related to medical device safety. In an interlaboratory study, fluid velocities and pressures were measured in a nozzle model to provide experimental validation for a companion ...
Weyeneth N - - 2011
Abstract Eocene ocean currents and prevailing winds correlate with over-water dispersals of terrestrial mammals from Africa to Madagascar. Since the Early Miocene (about 23 Ma), these currents flowed in the reverse direction, from the Indian Ocean towards Africa. The Comoro Islands are equidistant between Africa and Madagascar and support an endemic ...
Faria David Pedro - - 2011
The permeability of gases through uncompressed cork was investigated. More than one hundred samples were assessed from different plank qualities to provide a picture of the permeability distribution. A novel technique based on a mass spectrometer leak detector was used to directly measure the helium flow through the central area ...
Walter Gary R - - 2011
Recharge through intermittent and ephemeral stream channels is believed to be a primary aquifer recharge process in arid and semiarid environments. The intermittent nature of precipitation and flow events in these channels, and their often remote locations, makes direct flow and loss measurements difficult and expensive. Airborne and satellite optical ...
Lester Felicia - - 2011
OBJECTIVE: The Non-pneumatic Antishock Garment (NASG) is a compression device that has shown significantly decreased blood loss in cases of obstetric hemorrhage. However, there are no physiologic studies of the NASG in postpartum women. This study used Doppler ultrasound to measure the resistive index (RI) in the internal iliac artery, ...
Kung Ethan O - - 2011
The purpose of this article is to validate numerical simulations of flow and pressure incorporating deformable walls using in vitro flow phantoms under physiological flow and pressure conditions. We constructed two deformable flow phantoms mimicking a normal and a restricted thoracic aorta, and used a Windkessel model at the outlet ...
Colucci G - - 2011
Introduction:  ROTEM(®) is considered a helpful point-of-care device to monitor blood coagulation. Centrally performed analysis is desirable but rapid transport of blood samples and real-time transmission of graphic results are an important prerequisite. The effect of sample transport through a pneumatic tube system on ROTEM(®) results is unknown. The aims ...
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