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Results 101 - 150 of 899
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Mansueto Pasquale - - 2012
Cobalamin (vitamin B(12)) deficiency occurs with several disorders, involving different organs and systems, including blood, bowel, nervous system and eyes. Although the most important features are usually haematological ones, presence of neurological involvement, in the absence of blood count alterations, has just been described in the literature. Here we report ...
Yakut Zeynep Ilerisoy - - 2012
Purpose: To evaluate ocular blood flow dynamics by color Doppler ultrasonography (CDU) in patients with end-stage renal disease (ESRD). Additionally, to investigate the effect of dialysis type on ocular blood flow by comparing the findings of peritoneal dialysis (PD) subjects, hemodialysis (HD) subjects, and healthy controls. Material and methods: Forty ...
Sands Gh - - 2012
Chronic use of nonsteroidal anti-inflammatory drugs (NSAIDs) is associated with an increased risk of gastrointestinal (GI) toxicity, including occult blood loss and the development of clinically significant anemia. The aim of this study was to investigate the clinical importance of clinically significant anemia/blood loss. Pooled analysis of 51 blinded, controlled ...
Walkden Deborah - - 2012
To determine venesection patterns in hereditary haemochromatosis (HC) patients in Christchurch, New Zealand, their contribution to the blood supply, and reasons for deferral. Review of clinical records of 412 HC patients venesected by the NZ Blood Service at least once during 2009. Of 275 males and 137 females, 384 had ...
Eshoo Mark W - - 2012
Direct molecular tests in blood for early Lyme disease can be insensitive due to low amount of circulating Borrelia burgdorferi DNA. To address this challenge, we have developed a sensitive strategy to both detect and genotype B. burgdorferi directly from whole blood collected during the initial patient visit. This strategy ...
Zuhur Sayid Shafi - - 2012
To determine the role of peak systolic velocity, end-diastolic velocity and resistance indices of both the right and left inferior thyroid arteries measured by color-flow Doppler ultrasonography for a differential diagnosis between gestational transient thyrotoxicosis and Graves' disease during pregnancy. The right and left inferior thyroid artery-peak systolic velocity, end-diastolic ...
Bannach Oliver - - 2012
Prion diseases are transmissible neurodegenerative diseases affecting humans and animals. The agent of the disease is the prion consisting mainly, if not solely, of a misfolded and aggregated isoform of the host-encoded prion protein (PrP). Transmission of prions can occur naturally but also accidentally, e.g. by blood transfusion, which has ...
Lacroux Caroline - - 2012
The identification in the UK of 4 v-CJD infected patients thought to be due to the use of transfused Red Blood Cell units prepared from blood of donors incubating v-CJD raised major concerns in transfusion medicine. The demonstration of leucocyte associated infectivity using various animal models of TSE infection led ...
Andréoletti Olivier - - 2012
It is now clearly established that the transfusion of blood from variant CJD (v-CJD) infected individuals can transmit the disease. Since the number of asymptomatic infected donors remains unresolved, inter-individual v-CJD transmission through blood and blood derived products is a major public health concern. Current risk assessments for transmission of ...
Qvarnstrom Yvonne - - 2012
The laboratory diagnosis of Chagas disease is challenging because the usefulness of different diagnostic tests will depend on the stage of the disease. Serology is the preferred method for patients in the chronic phase, whereas PCR can be successfully used to diagnose acute and congenital cases. Here we present data ...
Zalpuri Saurabh - - 2012
Individuals exposed to red blood cell alloantigens through transfusion, pregnancy or transplantation may produce antibodies against the alloantigens. Alloantibodies can pose serious clinical problems such as delayed haemolytic reactions and logistic problems, for example, to obtain timely and properly matched transfusion blood for patients in which new alloantibodies are detected. ...
Sutherland Jayne S JS Medical Research Council Unit, Atlantic Road, Fajara, The Gambia, West Africa. - - 2012
Pleural TB is notoriously difficult to diagnose due to its paucibacillary nature yet it is the most common cause of pleural effusions in TB endemic countries such as The Gambia. We identified both cellular and soluble biomarkers in the pleural fluid that allowed highly accurate diagnosis of pleural TB compared ...
Pedroso Gabriela L GL Hospital de Clínicas de Porto Alegre, Centro de Pesquisa Experimental Laboratório de Hepatologia e Gastroenterologia Experimental, Porto Alegre, RS, Brasil. - - 2012
The zebrafish has been used as an animal model for studies of several human diseases. It can serve as a powerful preclinical platform for studies of molecular events and therapeutic strategies as well as for evaluating the physiological mechanisms of some pathologies. There are relatively few publications related to adult ...
Dake Michael D MD Department of Cardiothoracic Surgery, Standford University School of Medicine, Stanford, CA 94305-5407, USA. - - 2011
Chronic cerebrospinal venous insufficiency (CCSVI) is a term used to describe impaired venous drainage from the central nervous system (CNS) caused by abnormalities in anatomy and flow affecting the extracranial veins. Recently, it has been proposed that CCSVI may contribute to the pathogenesis of multiple sclerosis (MS). It is hypothesized ...
Bernstine Hanna - - 2011
Purpose: To prospectively determine whether fluorine 18 fluorodeoxyglucose (FDG) positron emission tomography (PET)/computed tomography (CT) early dynamic blood flow estimates could be used to discriminate hepatocellular carcinoma (HCC) from background liver and to characterize HCC in patients with and those without angioinvasion; and to evaluate the association between blood flow ...
Zhang Zhen-Du - - 2011
Coronary Flow Reserve (CFR) is an important index of coronary microcirculatory function. The objective of this study was to validate the reproducibility and accuracy of intravascular conductance catheter-based method for measurements of baseline and hyperemic coronary flow velocity (and hence CFR). The absolute coronary blood velocity was determined by measuring ...
King Deirdre M - - 2011
Polyvinyl alcohol cryogel (PVA-C) is presented as a vessel-mimicking material for use in anatomically realistic Doppler flow phantoms. Three different batches of 10% wt PVA-C containing (i) PVA-C alone, (ii) PVA-C with antibacterial agent and (iii) PVA-C with silicon carbide particles were produced, each with 1-6 freeze-thaw cycles. The resulting ...
Rice Thomas W - - 2011
The esophagus spans three body cavities and has no mesentery, continually borrowing or sharing vessels, lymphatics, and nerves with associated organs. However, constant along this path is an intricate mural structure. An understanding of the esophageal wall, its blood supply, lymphatic drainage, and innervation is essential for successful esophageal surgery.
Ragan Dustin K - - 2011
To test the ability of a multi-band RF pulse to reduce flow enhancement artifacts for steady state imaging without compromising temporal resolution or spatial coverage. Selectively spoiled composite RF pulses that provide simultaneous excitation and flow preparation were designed and tested by means of simulation, phantom, and in vivo measurements ...
Hyväluoma J - - 2011
On microstructured hydrophobic surfaces, geometrical patterns may lead to the appearance of a superhydrophobic state, where gas bubbles at the surface can have a strong impact on the fluid flow along such surfaces. In particular, they can strongly influence a detected slip at the surface. We present two-phase lattice Boltzmann ...
Nightingale M J - - 2011
Three EBA specified blood bag configurations ('Eurobloodpack') are described which are capable of meeting >80% of its member's requirements. These include a 'top-and-top' and two 'bottom-and-top' packs enabling aseptic, pre-donation collection of up to 40 ml of samples, 427·5-522·5 ml of whole blood and the preparation of an extensive range of blood ...
Krishnan Harinarayan - - 2011
Many flow visualization techniques, especially integration-based methods, are problematic when the measured data exhibits noise and discretization issues. Particularly, this is the case for flow-sensitive phase-contrast magnetic resonance imaging (PC-MRI) datasets which not only record anatomic information but also time-varying flow information. We propose a novel approach for the visualization ...
Huang Her-Hsiung - - 2011
Objectives: The goal of this study was to enhance the blood responses to titanium (Ti) surfaces used for dental implant application through the formation of a TiO(2) nano-mesh surface layer produced by a fast electrochemical anodization treatment. Material and methods: Electrochemical anodization treatments with different anodization currents and temperatures in ...
Koku Harun H Department of Chemical Engineering, University of Delaware, Newark, DE 19716, - - 2011
The flow behavior of a commercial polymeric monolith was investigated by direct numerical simulations employing the lattice-Boltzmann (LB) methodology. An explicit structural representation of the monolith was obtained by serial sectioning of a portion of the monolith and imaging by scanning electron microscopy. After image processing, the three-dimensional structure of ...
Mordant David J - - 2011
To assess the accuracy of human blood oximetry measurements in a model eye with a hyperspectral fundus camera. Seven human whole blood samples (two arterial, five venous) were obtained, the oxygen saturations measured with a CO oximeter, and the samples inserted into quartz tubes with internal diameters of 100 and ...
Xu Ying - - 2011
In this paper, numerical simulations are used to study the turbulent wind noise reduction effect of microphone windscreens with varying shapes and flow resistivities. Typical windscreen shapes consisting of circular, elliptical, and rectangular cylinders are investigated. A turbulent environment is generated by placing a solid circular cylinder upstream of the ...
Markl Michael - - 2011
To systematically investigate the scan-rescan reproducibility and observer variability of flow-sensitive four-dimensional (4D) MRI in the aorta for the assessment of blood flow and global and segmental wall shear stress. ECG and respiration-synchronized flow-sensitive 4D MRI data (spatio-temporal resolution = 1.7 × 2.0 × 2.2 mm(3) /40.8 ms) were acquired ...
Dunning K - - 2011
Abstract Wright-Giemsa staining is a common procedure that is performed routinely in hematology laboratories. Consistency in intra-laboratory staining quality is essential for accurate morphological interpretation of blood smears. Although the Wright-Giemsa stain can be challenging to perform, the methods illustrated here have provided consistent, high quality stains in the Special ...
Roeykens H - - 2011
An early determination of pulpal vitality is crucial with respect to a correct differential diagnosis of revascularisation or necrosis and its treatment. Sensibility tests (cold, heat, electrical pulp test) in combination with radiographs are commonly promoted. However these tests are arbitrary, based on sensations and therefore not always reliable. In ...
Hariharan Prasanna - - 2011
This study is part of a FDA-sponsored project to evaluate the use and limitations of computational fluid dynamics (CFD) in assessing blood flow parameters related to medical device safety. In an interlaboratory study, fluid velocities and pressures were measured in a nozzle model to provide experimental validation for a companion ...
Weyeneth N - - 2011
Abstract Eocene ocean currents and prevailing winds correlate with over-water dispersals of terrestrial mammals from Africa to Madagascar. Since the Early Miocene (about 23 Ma), these currents flowed in the reverse direction, from the Indian Ocean towards Africa. The Comoro Islands are equidistant between Africa and Madagascar and support an endemic ...
Faria David Pedro - - 2011
The permeability of gases through uncompressed cork was investigated. More than one hundred samples were assessed from different plank qualities to provide a picture of the permeability distribution. A novel technique based on a mass spectrometer leak detector was used to directly measure the helium flow through the central area ...
Walter Gary R - - 2011
Recharge through intermittent and ephemeral stream channels is believed to be a primary aquifer recharge process in arid and semiarid environments. The intermittent nature of precipitation and flow events in these channels, and their often remote locations, makes direct flow and loss measurements difficult and expensive. Airborne and satellite optical ...
Lester Felicia - - 2011
OBJECTIVE: The Non-pneumatic Antishock Garment (NASG) is a compression device that has shown significantly decreased blood loss in cases of obstetric hemorrhage. However, there are no physiologic studies of the NASG in postpartum women. This study used Doppler ultrasound to measure the resistive index (RI) in the internal iliac artery, ...
Kung Ethan O - - 2011
The purpose of this article is to validate numerical simulations of flow and pressure incorporating deformable walls using in vitro flow phantoms under physiological flow and pressure conditions. We constructed two deformable flow phantoms mimicking a normal and a restricted thoracic aorta, and used a Windkessel model at the outlet ...
Colucci G - - 2011
Introduction:  ROTEM(®) is considered a helpful point-of-care device to monitor blood coagulation. Centrally performed analysis is desirable but rapid transport of blood samples and real-time transmission of graphic results are an important prerequisite. The effect of sample transport through a pneumatic tube system on ROTEM(®) results is unknown. The aims ...
Feng Rui - - 2011
Flow and stresses induced by blood flow acting on the blood cellular constituents can be represented to a certain extent by a continuum mechanics approach down to the order of the μm level. However, the molecular effects of, e.g., adhesion/aggregation bonds of blood clotting can be on the order of nm. ...
O'Brien Dominique S - - 2011
Passive samplers for phosphate were calibrated in the laboratory over a range of flow velocities (0-27 cm s(-1)) and ionic strengths (0-0.62 mol kg(-1)). The observed sampling rates were between 0.006 and 0.20 L d(-1). An empirical model allowed the estimation of these sampling rates with a precision of 8.5%. ...
Partal A - - 2011
Objectives: To create a low-cost protocol for the production of autologous serum eye drops (ASEs) by blood collection and processing centres using standard equipment and staff already available. The protocol must observe local and federal regulatory authorities' requirements for good manufacturing practice. Aim: The final aim is to improve accessibility ...
Bieging Erik T - - 2011
PURPOSE: To estimate surface-based wall shear stress (WSS) and evaluate flow patterns in ascending aortic dilatation (AscAD) using a high-resolution, time-resolved, three-dimensional (3D), three-directional velocity encoded, radially undersampled phase contrast magnetic resonance sequence (4D PC-MRI). MATERIALS AND METHODS: 4D PC-MRI was performed in 11 patients with AscAD (46.3±22.0 years) and ...
Conrado Luis Augusto Lupato - - 2011
Background  Therapeutic effects have been attributed to far-infrared (FIR) radiation emitted from different types of sources. One class of such infrared emitters consists of ceramics in a powdered form, which allows for its incorporation into creams and fabrics. Such ceramic materials emit in the FIR when subjected to body temperature. ...
Takagi Daisuke - - 2011
Many processes in geophysical and industrial settings involve the flow of granular materials down a slope. In order to investigate the granular dynamics, we report a series of laboratory experiments conducted by releasing grains at a steady rate from a localized source on a rough inclined plane. Different types of ...
Montanero J M - - 2011
The global stability of the steady jetting mode of liquid jets focused by coaxial gas streams is analyzed both theoretically and experimentally. Numerical simulations allow one to identify the physical mechanisms responsible for instability in the low viscosity and very viscous regimes of the focused liquid. The characteristic flow rates ...
Liu Biyue B Department of Mathematics, Monmouth University, West Long Branch, NJ 07764, - - 2011
The objective of this work is to investigate the effect of non-Newtonian properties of blood on the wall shear stress (WSS) in atherosclerotic coronary arteries using both Newtonian and non-Newtonian models. Numerical simulations were performed to examine how the spatial and temporal WSS distributions are influenced by the stenosis size, ...
Dorronsoro Carlos - - 2011
An Allegretto Eye-Q laser platform (Wavelight GmbH, Erlangen, Germany) was used to study the effect of air-flow speed on the ablation of artificial polymer corneas used for testing refractive surgery patterns. Flat samples of two materials (PMMA and Filofocon A) were ablated at four different air flow conditions. The shape ...
Chandra Ankur - - 2011
PURPOSE: Duplex surveillance of arterial stents has focused on detecting in-stent restenosis. Although velocity is commonly reported, that differs from blood flow, and patency of arterial prostheses is flow-dependent. Preliminary evaluation was performed to determine if postprocedure peak systolic blood flow (PSF) through stents correlates with rate of repeat intervention ...
Rogers Michelle - - 2011
The behaviour of droplets entering a microfluidic chamber designed to house microelectrode detectors for real time analysis of clinical microdialysate is described. We have designed an analysis chamber to collect the droplets produced by multiphase flows of oil and artificial cerebral spinal fluid. The coalescence chamber creates a constant aqueous ...
Mozharov Sergey - - 2011
A novel method has been devised to derive kinetic information about reactions in microfluidic systems. Advantages have been demonstrated over conventional procedures for a Knoevenagel condensation reaction in terms of the time required to obtain the data (fivefold reduction) and the efficient use of reagents (tenfold reduction). The procedure is ...
Leblanc Serge Emile - - 2011
It is well known that red blood cell scattering has an impact on whole blood oximetry as well as in vivo retinal oxygen saturation measurements. The goal of this study was to quantify the impact of small angle forward scatter on whole blood oximetry for scattering angles found in retinal ...
von Knobelsdorff-Brenkenhoff Florian - - 2011
Objective: The hemodynamics in proximity to stented aortic bioprostheses still differ from that under physiological conditions. This may prevent desired cardiac remodeling and promote aortic diseases. Further improvements in prosthetic technology require an accurate survey of the flow conditions on the prosthetic level and in the ascending aorta. Cardiovascular magnetic ...
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