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Results 401 - 450 of 1245
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Tessitore Nicola - - 2006
BACKGROUND: Clinical practice for stenosis detection and treatment in arteriovenous fistulas (AVFs) varies widely and is largely dictated by local customs and expertise. METHODS: In May 2003, a questionnaire was sent to 32 hemodialysis (HD) facilities in north-eastern Italy, to assess the prevalence of patients with an AVF; the screening ...
Pannu Neesh - - 2006
Long-term dialysis is often delivered through tunneled central venous catheters (CVC) despite their associated morbidity and mortality rates. Because poor solute clearance might contribute to this risk, we examined the relation between blood pump speed (QB), access recirculation (AR), and dialysis delivery in patients with CVC. We conducted a prospective ...
Mercadal L - - 2006
The optical blood volume curve sometimes presents either a positive or a negative rapid and reversible variation (spike) during the step of the dialysate conductivity, automatically set by the monitor for the ionic dialysance (ID) measurement. We studied whether this feature was in relation with access recirculation. Firstly, we studied ...
Lawrence E L - - 2006
The treatment for urinary incontinence, a common condition affecting a considerable number of older and disabled members of society, involves the use of a Foley catheter for drainage of the bladder. The basic design of the catheter has remained the same for over seventy years. Despite modifications to the materials ...
Van Biesen Wim - - 2006
BACKGROUND: The Genius dialysis system is advocated as a tool to perform slow extended daily dialysis (SLEDD) in patients with acute renal failure at the intensive care unit. At low blood flows however, it is sometimes problematic to maintain sufficient systemic pressure in the dialysate circuit, a problem that can ...
Bolasco P - - 2006
AIM: The purpose of this study was to optimize the operative and analytical methodologies to a more exact determination of intradialytic kinetics of the phosphates (P) tested in hemodialysis (HD) and in on-line hemodiafiltration with endogenous reinfusion (HFR - Hemo Filtrate Reinfusion). METHODS: The mass balance measurements of urea and ...
Ash S R - - 2006
Although highly successful as transcutaneous access devices, today's peritoneal dialysis catheters still have imperfect hydraulic function, biocompatibility and resistance to infection. Success of Tenckhoff catheters is greatly improved by the proper positioning of deep and subcutaneous cuffs and intraperitoneal segment. Newer peritoneal catheter designs are intended to improve hydraulic function, ...
Copeland Sandra D - - 2006
Patients, like those with ESRD, who have lost the ability to filter excess proteins from their bodies are at risk to develop beta-2-microglobin amyloidosis, also known as dialysis-related amyloidosis (DRA). When the kidneys do not work efficiently, a protein called beta-2-microglobulin can build up in the blood. Eventually, these molecules ...
Durand Pierre-Yves - - 2006
This chapter exposes the clinical effects of different APD schedules. Clinical studies have shown that Na removal is lower with APD compared to CAPD. Therefore the loss of residual renal function requires continuous therapy with long day-dwell of polyglucose dialysate. Peritoneal small molecule clearances are closely determined by the hourly ...
Testa Angelo - - 2006
BACKGROUND: Current methods of renal replacement therapy, combining convection and diffusion, are largely unsatisfactory in removing uremic toxins. Adsorption is a third mechanism that has been applied in extracorporeal therapy. This study evaluates the impact of hemodiafiltration with on-line regeneration of ultrafiltrate, a new two-step integrated sorbent system, on in ...
Patzer John F JF - - 2006
Bound solute dialysis (BSD), often referred to as "albumin dialysis" (practiced clinically as the molecular adsorbents recirculating system, MARS, or single-pass albumin dialysis, SPAD) or "sorbent dialysis" (practiced clinically as the charcoal-based Biologic-DT), is based upon the thermodynamic principle that the driving force for solute mass transfer across a dialysis ...
Tal Michael G - - 2006
Current literature suggests that side holes may be detrimental to dialysis catheter performance. Today, these catheters are primarily available with side holes. The purpose of this study was to compare flow rates, infection rate, and survival of side hole vs. non side hole hemodialysis catheters. Over a 16-month period patients ...
Ronco Claudio - - 2006
Peritoneal dialysis (PD) is still underutilized as home based renal replacement therapy and in-patient treatment of acute renal failure. Hindering the expansion of PD is poor solute clearance, which is a result of the intermittent dwell technique. Continuous flow PD is an old concept that has demonstrated urea clearances from ...
Braasch Matthew - - 2006
OBJECTIVES: To evaluate in an in vitro study the irrigation and drainage capabilities of a variety of available catheters. Three-way Foley catheters are used when irrigation of the bladder is anticipated to prevent or manage blood clots in the bladder. METHODS: Six operators applied maximal one-handed pressure irrigation with a ...
Griveas Ioannis - - 2006
The immune defect in hemodialysis (HD) patients is associated with a monocyte dysfunction, including an increase in the production of proinflammatory cytokines. Blood membrane contact leads to an increase in cellular activation and sequestration into the capillary bed of the lung. The influence of the sequestration on the number of ...
Fiore Gianfranco B - - 2006
The potential of convective solute transport for blood purification has been widely explored. New techniques (such as hemodiafiltration), based on a combination of diffusion and convection techniques, have been developed. Owing to the internal filtration/backfiltration (IF/BF) phenomenon, high-flux dialysis also relies on a convective component, which, however, is hard to ...
Belardi Jorge A - - 2005
OBJECTIVE: To report the safety and feasibility of a new occluding thermographic catheter in patients with coronary artery disease. BACKGROUND: Although plaque temperature heterogeneity is shown in atheromatous plaques, significant underestimation is encountered due to the cooling effect of the uninterrupted blood flow. METHODS: The catheter was positioned at the ...
Jonsson P - - 2005
Haemodialysis (HD) machines are IEC-classified as I type B. When central dialysis catheters (CDCs) are used for access, there will be close electrical contact with the heart. To investigate the risk for HD patients, the leakage of current through the tubing set was measured during in vitro dialysis performed according ...
Huisman Roel M - - 2005
BACKGROUND: Knowledge of the variability of a measurement method is essential for its clinical application. We investigated the variability of shunt flow measurements, since this is a relatively neglected area in the literature. In particular, no direct comparison of between-session and within-session variability was available until now. METHODS: During two ...
Brendolan A - - 2005
New dialyzers are designed to optimize the convective and diffusive components of solute transport. Asahi Kasei Medical Co.,Ltd.has developed a new high flux dialyzer series called Rexeed with improved flow distributions. We evaluated the in vivo dialytic performance of two dialyzers of the Rexeed series: Rexeed-18A and Rexeed-25A (1.8 m2 ...
Eloot Sunny - - 2005
Some studies found that the removal of middle molecules has a long-term effect on mortality and, even more, is enhanced by high-flux dialysis. In order to enhance middle molecule removal in a low-flux dialyzer, the present study aimed at investigating the combined impact of dialyzer flows and membrane surface area. ...
Tal Michael G - - 2005
PURPOSE: The purpose of this study was to evaluate in vivo recirculation of a new bi-directional dialysis catheter with a symmetric tip design and compare it to currently marketed staggered and split tip catheters. MATERIALS AND METHODS: Twelve catheters were placed in three 70-kg male swine. The catheters were connected ...
Price Corbett A - - 2005
Seven measures are indispensable to healthcare financial executives for assessing their organizations' financial well-being. Two are accrual based: Cleverley's Financial Strength Index Altman's modified Z score. The rest are cash-flow based: Operating cash flow ratio. Funds flow coverage ratio. Cash interest coverage ratio. Cash flow to total debt ratio. Total ...
Canales Benjamin K - - 2005
OBJECTIVES: To evaluate the impact of percutaneous nephrostomy catheter configuration on drainage flow and retention strength. METHODS: The Cook nephrostomy 16F (symmetric balloon), Bardex Council 16F (eccentric balloon), Microvasive Flexima 14F (pigtail), and Bardex Malecot 16F (flange) nephrostomy catheters were attached to an artificial renal pelvis (12-in.-round latex balloon). The ...
Stefanidis I - - 2005
BACKGROUND: Several effects of hemodialysis, including hemoconcentration, alterations of hemostasis or hemorheology and endothelial activation, could potentially interfere with cerebral blood flow (CBF) regulation. These treatment-specific changes may also be crucial for the enhanced incidence of stroke in uremic patients. Nevertheless, the influence of hemodialysis on CBF has not been ...
Franssen Casper F M - - 2005
BACKGROUND: In patients with primary hyperoxaluria (PH) and oliguric end-stage renal disease, oxalate removal is largely dependent on the clearance by dialysis. Data on the oxalate clearance of newer dialyser types are scarce or absent. Therefore, we measured oxalate clearances of seven dialysers in a single 52-year-old female patient with ...
Eloot S - - 2005
For a better insight in dialyzer efficiency with respect to local mass transport in a low flux dialyzer (Fresenius F6HPS), blood and dialysate flow distributions were visualized with computational fluid dynamic (CFD) simulations, which were validated with single photon emission computed tomography (SPECT) imaging. To visualize blood-side flow while avoiding ...
Mehmedović N - - 2005
On-line Clearance Monitoring (OCM) provides frequent and precise information about urea clearance values during haemodialysis. In the case of blood access recirculation, it is presumed that urea clearance values on OCM would be lower and suspect to blood access malfunction. In order to check the relation between significantly lower urea ...
Shiowatana Juwadee - - 2006
A system for dynamic continuous-flow dialysis during intestinal digestion for an in vitro simulation of gastrointestinal digestion is presented as an alternative to human and animal in vivo methods for estimation of the bioavailability of minerals. The method is based on the in vitro batch dialysis method described by Miller, ...
Bouts Antonia H M - - 2005
Children treated by peritoneal dialysis (PD) are at increased risk of infections. IgG receptors (FcgammaRs) and complement receptors (CRs) on white blood cells (WBCs) are important for the phagocytic process. We have investigated FcgammaR and CR expression on monocytes, macrophages and neutrophils in blood and in peritoneal dialysis effluent (PDE) ...
Bamgbola Oluwatoyin F - - 2005
Hemodialysis (HD) catheter occlusion is a common cause of poor blood flow and inadequate dialysis. In order to address this problem in our pediatric dialysis unit, we elected to use short (2-h) infusions of low-dose recombinant tissue plasminogen activator (rtPA) for thrombolysis of occluded catheters. Catheters meeting diagnostic criteria for ...
Mariano Filippo - - 2005
BACKGROUND: As removal of pro-inflammatory cytokines is limited in conventional diffusive or convective extracorporeal therapies, we studied in two polysulphone membranes with an industrial albumin sieving coefficient of 0.05 (Type A) and 0.13 (Type B) cytokine (IL-6, IL-8, IL-1beta, IL-1ra, TNF-alpha) and plasma protein (albumin, cystatin C, total proteins) permeability ...
Treacy P John - - 2005
BACKGROUND: Measurement of blood flow within native arteriovenous fistula during haemodialysis is recommended to detect incipient fistula failure. In the present study the value of such flow measurements was assessed in a group of patients on maintenance haemodialysis, with access via native arteriovenous fistulas. METHODS: Flow was measured using the ...
Everdell Nicholas L - - 2005
Babies weighing under 6 kg are difficult to dialyse, especially those as small as 1 kg. Peritoneal dialysis is easier than haemodialysis, but is not always possible, and clears molecules less efficiently. Two factors complicate haemodialysis. First, extracorporeal circuits are large relative to a baby's blood volume, necessitating priming with ...
Cortez Andrew J - - 2005
Vascular accesses consist of permanent arteriovenous (AV) accesses (autogenous fistulas and synthetic grafts) and venous accesses (central venous catheters [CVCs]). AV accesses have fewer complications than venous accesses, and are therefore the preferred hemodialysis access. An important additional issue is whether the type of access influences adequacy of dialysis (i.e. ...
Bihl Geoffrey R - - 2005
BACKGROUND: Specifications of dialyzer performance are generally based on in vitro measurements. There is, however, a shortage of data on dialyzer performance in vivo. The aim of this study was to use continuous measurement of technetium-99m-diethyltriaminepentaacetic acid (Tc-99m-DTPA) blood concentration as a means of continuously monitoring dialyzer function in vivo ...
Teraoka Tomohisa - - 2005
BACKGROUND: In clinical studies, it has been difficult to evaluate the influence of haemodialysis (HD) parameters on HD clearance (CL(HD)) and reduction rate (RR) of non-ionic contrast medium during HD sessions. We therefore predicted clinical values of CL(HD) and RR of iopromide, a non-ionic contrast medium, from findings obtained from ...
Gueler F - - 2005
BACKGROUND: We explored whether biocompatible dialyzer membranes modulate the inflammatory response during blood contact in patients with systemic inflammation. METHODS: 15 patients with end-stage renal disease and systemic inflammation (mean serum C-reactive protein 86 +/- 4 mg/l) were randomly treated with Cuprophan (CU), polyamide (PA) and vitamin-E coated (VEC) membrane-based ...
Morgera Stanislao - - 2005
BACKGROUND: Citrate anticoagulation is an excellent alternative to heparin anticoagulation for patients at high risk of bleeding requiring continuous renal replacement therapy. However, citrate anticoagulation has some potential adverse effects such as metabolic alkalosis and acidosis, hypernatremia, hypo- and hypercalcemia. Thus, most citrate anticoagulation protocols use specially designed dialysis fluids ...
Polaschegg Hans-Dietrich - - 2005
Basic functions of hemodialysis machines are described. The paper focuses on essential treatment parameters and safety aspects. The cause of safety hazards and protective systems for amelioration of these hazards are described. With the exception of hemolysis caused by obstructions in the extracorporeal circuit and blood losses caused by user ...
Zyga S - - 2005
The aim of this study was the exploration and correlation of the influence of variations in blood flow and dialysate flow on haemodialysis adequacy through the quantitative indexes Kt/V, TACurea and PCR. A prospective study of 48 patients subjected to haemodialysis was carried out. The collection of data included taking ...
Ronco Claudio - - 2005
Diffusion and convection are the main mechanisms involved in the membrane separation processes occurring in extracorporeal hemodialysis. Operational parameters should be optimized in hollow fiber hemodialyzers to achieve the maximal efficiency. The nature of blood which is a non Newtonian fluid, requires specific attention in the design of dialyzers to ...
O'Dwyer H - - 2005
PURPOSE: In a prospective randomized study a standard dual-tip hemodialysis catheter (PermCath, Sherwood Medical, St. Louis, MO, USA) was compared with a newer split-lumen catheter (Ash Split, Medcomp, Harleysville, PA, USA). METHODS: Sixty-nine patients (42 men, 27 women; mean age 62 years) were randomized to receive either the Ash Split ...
Niwayama Jun - - 2005
The management of blood pressure in hemodialysis patients greatly affects not only their quality of life, but also the duration of dialysis (dialysis life). Approximately 25% of dialysis patients suffer from continuous low blood pressure; however, the relationship between blood pressure and blood flow during dialysis has not been established. ...
Menegatti Elisa - - 2005
AIM: The aim of the study was to evaluate biocompatibility of anew polystyrene-type adsorbent (BetaSorb) designed for hemoperfusion, using second-level biomolecular analyses. The device has recently been developed to enhance beta2-microglobulin removal during hemodialysis. Molecular structure and chemical modifications of the surface beads of this cartridge should prevent exposure of ...
Adolfo Martinez Gustavo G U.D.E.F.A. SEDENA, Mexico, DEE, CREB, Technical University of Catalonia, Barcelona, - - 2005
The present work shows the development of a low-cost system to measure on-line blood urea concentration during dialysis procedures using optical sensor in the visible range. The objective in this project is obtaining the quantification of urea on-line during practices of the hemodialysis treatments. For which it has been considered ...
Goraca Anna - - 2004
OBJECTIVE: Magnocellular neuroendocrine cells of the supraoptic nucleus of the hypothalamus produce and release the hormones vasopressin and oxytocin in response to a variety of stimuli to regulate body water and salt as well as and parturition and lactation. The aim of the present study was to estimate oxytocin release ...
Di Filippo Salvatore - - 2004
BACKGROUND: An adequate estimation of urea distribution volume (V) in hemodialysis patients is useful to monitor protein nutrition. Direct dialysis quantification (DDQ) is the gold standard for determining V, but it is impractical for routine use because it requires equilibrated postdialysis plasma water urea concentration. The single pool variable volume ...
Tessitore Nicola - - 2004
BACKGROUND: Stenosis is the main cause of arteriovenous fistula (AVF) failure. It is unclear, however, if surveillance for stenosis enhances AVF function and longevity and if there is an ideal time for intervention. METHODS: In a 5-year randomized, controlled, open trial we compared blood flow surveillance and pre-emptive repair of ...
Jegger David - - 2004
Since the initiation of cardiac surgery using cardiopulmonary bypass, little progress has been made concerning the design of catheters for vascular access. However, in the last few years, research in this specialized field has established that catheter performance not only depends on size but also on the catheter's design. The ...
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