Search Results
Results 301 - 350 of 1236
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Lindley Elizabeth J - - 2009
BACKGROUND: The availability of haemodialysis machines equipped with on-line clearance monitoring (OCM) allows frequent assessment of dialysis efficiency and adequacy without the need for blood samples. Accurate estimation of the urea distribution volume 'V' is required for Kt/V calculated from OCM to be consistent with conventional blood sample-based methods. METHODS: ...
Dechmann-Sültemeyer Thomas - - 2009
BACKGROUND: A number of medical, mostly immune-mediated conditions call for a combination therapy consisting of plasmapheresis and haemodialysis. While the two treatments are most commonly applied separately, we describe here the technical details of providing a combined 'tandem' treatment. Method. The components of a dialyzer (polysulfon membrane) and plasma filter ...
Maynor Lena M - - 2008
STUDY OBJECTIVES: To assess the influence of in vitro and in vivo hemodialysis with a new high-flux dialyzer on the clearance of cefazolin and cefepime; to assess the correlation of in vivo dialytic clearance of these antibiotics with blood flow rate; and to assess the correlation between in vitro and ...
Tochihara Yuka - - 2008
BACKGROUND: Haemodialysis (HD) is associated with the acute loss through the dialysis membrane of biochemical factors either enhancing [folic acid (F)] or impairing [asymmetric dimethylarginine (ADMA)] arterial function. Changes in these opposing factors might explain the absence of significant modifications in arterial function during HD. We speculated that intra-HD, instead ...
Krieter Detlef H - - 2008
Optimizing solute removal at minimized albumin loss is a major goal of dialyzer engineering. In a prospective, randomized, crossover study on eight patients (age 63 +/- 14 years) on maintenance hemodialysis, the new Baxter Xenium 170 high-flux dialyzer (BX), which contains a 1.7-m(2) PUREMA H dialysis membrane, was compared with ...
Malik J - - 2008
Distal hypoperfusion ischemic syndrome (DHIS), commonly referred to as hand ischemia or 'steal' after dialysis access placement, occurs in 5-10% of cases when the brachial artery is used, or 10 times that of wrist arteriovenous fistulas (AVFs) using the radial artery. It is typically seen in elderly women with diabetes, ...
Prunet Bertrand - - 2008
BACKGROUND: To reduce the risk of accidental needlestick injuries, first active then passive safety devices were developed on IV catheters. However, whether these catheters are easy to implement and really protect personnel from accidental needlestick is untested. METHODS: In this prospective randomized survey, we compared a passive safety catheter with ...
Leffel Elizabeth K - - 2008
This study was originally designed to collect data on the natural history of inhalational anthrax in a new nonhuman primate model. An uncontrollable event created a new experimental condition which allowed us to retrospectively evaluate the power of the innate immune system to protect from an aerosol exposure of B. ...
Kim J C - - 2008
Perfusion computed tomography (PCT) is a means to rapidly and easily evaluate cerebral perfusion in patients presenting with acute stroke symptoms, which provides insights into capillary-level hemodynamics. In this study, we used PCT to analyze the 3-dimensional dialysate flow in a low-flux hemodialyzer equipped with a standard fiber bundle. The ...
Schlitt Axel - - 2008
BACKGROUND: The Organization to Assess Strategies in Acute Ischemic Syndromes trials showed that fondaparinux (fonda) is at least as effective and safe as unfractionated heparin (UFH) and enoxaparin (enoxa) in acute coronary syndromes. Unexpectedly, there was an increase in catheter-related thrombus formation during percutaneous coronary interventions in fonda-treated patients. METHODS: ...
Tessitore Nicola - - 2008
BACKGROUND: Access blood flow (Qa) measurement is the recommended method for fistula (AVF) surveillance for stenosis, but whether it may be beneficial and cost-effective is controversial. METHODS: We conducted a 5-year controlled cohort study to evaluate whether adding Qa surveillance to unsystematic clinical monitoring (combined with elective stenosis repair) reduces ...
Lin Chia-Hsun - - 2008
Autogenous arteriovenous fistula (AVF) has proven to be the optimal vascular access for the majority of hemodialysis patients due to its durability and low complication rates. The purpose of this study is to determine the value of intraoperative blood flow measurement with respect to AVF short-term outcome. A prospective cohort ...
Ben-Ami Ronen - - 2008
Candida spp. are important causes of nosocomial bloodstream infections. Around 80% of patients with candidemia have an indwelling central venous catheter (CVC). Determining whether the CVC is the source of candidemia has implications for patient management. We assessed whether the time to detection of Candida species in peripheral blood (time ...
Lee Kyungsoo - - 2008
Midsize molecule retention is related with renal-failure-associated mortality. Here, the authors describe a new dialysis modality, pulse push/pull hemodialysis (PPPHD), which increases convective clearance. Blood and dialysate are circulated by a pulsatile pump, but with pulsatile flow patterns that are 180 degrees out of phase. This causes blood-to-dialysate pressure gradients ...
Ashavaid Tester F - - 2008
Preanalytical errors contribute to a large proportion of total laboratory errors. In order to achieve continuous laboratory improvement, it is important to focus on all phases of patient specimen testing i.e. preanalytical, analytical and post-analytical. With large variations in the way venous blood specimens are collected using diverse devices in ...
Tonelli Marcello - - 2008
BACKGROUND: Observational studies indicate that routine measurements of access blood flow and use of Doppler ultrasound improve vascular access outcomes in hemodialysis patients, but randomized trials reached conflicting conclusions. STUDY DESIGN: Systematic review and meta-analysis. SETTING & POPULATION: Adult hemodialysis patients with arteriovenous accesses. Selection Criteria for Studies: Randomized trials. ...
Back Martin R - - 2008
BACKGROUND: Persistent poor patency rates of arteriovenous fistulae and bridge grafts for dialysis access prompted us to investigate whether flow parameters derived from an initial postconstruction, precannulation duplex study could predict access longevity or direct remedial procedures to salvage nonmaturing conduits. METHODS: We analyzed 125 consecutive dialysis access conduits (34 ...
Kanagasundaram Nigel S - - 2008
BACKGROUND: Blood-side dosing methods may overestimate urea removal in comparison to dialysate-side measurements during intermittent HD (IHD) for acute renal failure (ARF). The present study sought to quantify this mass balance error (MBE) and explore potential explanatory factors. METHODS: Prospective, formal, blood-side urea kinetic modelling was performed in serial sessions ...
Tiranathanagul K - - 2008
Measurement of the vascular access flow rate (Q(a)) is a widely accepted method for surveillance and predicting access failure. Among current practical methods, the ultrasound dilution technique is standard, but this requires a costly device available in few hemodialysis (HD) centers. Here, we devised a simple hemoglobin dilution technique to ...
Grouzmann Eric - - 2008
PURPOSE: A misleading blood tacrolimus concentration (BTC) value caused by the contamination of a central venous catheter previously used for tacrolimus administration is described. SUMMARY: A 59-year-old woman with severe chronic obstructive pulmonary disease successfully underwent double lung transplantation. In the intensive care unit, she received a continuous i.v. infusion ...
Watnick Suzanne - - 2008
BACKGROUND AND OBJECTIVES: Previous reports have described white particulate matter in banked blood components, but no prior public reports describe such matter in blood tubing during the course of routine in-center hemodialysis. This report describes the events, investigations, and preliminary conclusions associated with the spontaneous formation of adherent white thrombus ...
Válek Martin - - 2008
AIM: To assess the variability of blood flow (QVA) through a native arteriovenous fistula (AVF) in the long-term and to determine the QVA reduction at which an intervention is appropriate. PATIENTS AND METHODS: The study was performed in a group of 34 chronic hemodialysis patients with no history of a ...
Brummelhuis Walter J - - 2008
Methods to continuously measure absolute refill during dialysis are not available. It would be useful to have such a method because it would allow investigating the mechanism of refill the effect of interventions. We designed a feedback algorithm that adjusts ultrafiltration rate (QUF) according to hemoglobin (Hb) concentration changes in ...
Lee Kyungsoo - - 2008
A new dialysis modality was devised to increase convective mass transfer. Blood and dialysate are circulated by a pulsatile pump, but with pulsatile flow patterns that are 180 degrees out of phase, which causes blood-to-dialysate pressure gradients to oscillate between positive and negative. In the present study, hemodialytic performance of ...
Mandolfo Salvatore - - 2008
In the last few years, the number of hemodialysis patients with inadequate blood flow (Qb) rates has increased due to vascular access problems. To avoid a clinical status of underdialysis, these patients need long-lasting dialysis sessions. However, other factors aimed to optimize the dialysis dose have to be considered. High-efficiency ...
de Freitas Lilyan Walkyria Caleiro - - 2008
AIMS: The use of hemodialysis temporary dual-lumen catheters is often complicated by infections, which may be a significant cause of death among patients with end stage renal disease (ESRD). The aim of this study was to assess the incidence of bacteremia and bacterial colonization related to non-tunneled, non-cuffed, dual-lumen temporary ...
Ishida Hitoshi - - 2008
Recently, expired gases are analyzed non-invasively for monitoring the substances in the blood. Breath ammonia has been shown to correlate with BUN (blood urea nitrogen) and Cr (creatinine), both of which are indicators of solute removal in hemodialysis. In this study, breath ammonia concentration was continuously measured using a crystal ...
Winkler Roland E - - 2008
BACKGROUND: In CKD stage 5 diabetic patients (DM), only approximately half of the interdialytic weight gain was accounted for by sodium intake. The other half was due to pure water gain, probably caused by hyperglycemia. Dialysis treatment faces two major troubles: the removal of the extra amount of water and ...
Grzegorzewska Alicja E - - 2008
OBJECTIVE: The hemodialysis (HD) team should deliver single-pool variable-volume (SPVV) urea Kt/V>or=1.2. At present dialysis machines provide online assessment of Kt/V. The aim of our study is to assess if online Kt/V and SPVV urea Kt/V yield similar values and if it may be replaced in evaluation of HD adequacy. ...
Viganò Sara M - - 2008
The most appropriate dialysate composition is one of the central topics in dialysis treatment. The prescription of a certain dialysate composition could change in order to obtain not only an adequate blood purification but also a high tolerability. Sodium balance represents the cornerstone of cardiovascular stability and good blood pressure ...
Lacson Eduardo E - - 2008
Routine access flow (AF) surveillance is recommended by the Kidney Disease Outcomes Quality Initiative as one of several components for an arteriovenous vascular access maintenance program. A reliable, but affordable, measurement tool is needed for outpatient hemodialysis facilities. Diagnostic test study. 50 adult patients with 27 grafts and 23 fistulas ...
Mora-Bravo Franklin G - - 2008
In hemodialysis, extracorporeal blood flow (Qb) recommendation is 300-500 mL/min. To achieve the best Qb, we based our prescription on dynamic arterial line pressure (DALP). This prospective study included 72 patients with catheter Group 1 (G1), 1877 treatments and 35 arterio-venous (AV) fistulae Group 2 (G2), 1868 treatments. The dialysis ...
Reyns L-M LM Renal Division, Department of Internal Medicine, Ghent University Hospital, Belgium. - - 2008
We describe the case of a 70-year-old woman who presented with a pulsating mass in the left supraclavicular region during a haemodialysis session. The frequency of the pulsations, parallel to that of the dialysis-related blood flow cycle, without blood loss at the exit site, indicated that this observation could potentially ...
Eloot S - - 2008
Several studies have stressed the importance of dialysis time in the removal of uremic retention solutes. To further investigate this, nine stable chronic hemodialysis patients were dialyzed for 4, 6, or 8 h processing the same total blood and dialysate volume by the Genius system and high-flux FX80 dialyzers. Inlet ...
Gura V - - 2008
Ultrafiltration is effective for treating fluid overload, but there are no suitable machines for ambulatory treatment. This study summarizes the use of a light-weight wearable continuous ambulatory ultrafiltration device consisting of a hollow fiber hemofilter, a battery operated pulsatile pump, and two micropumps to control heparin administration and ultrafiltration. Six ...
Schneditz D - - 2007
It is well known that the measurement of access flow by one of the various dilution techniques requires the reversal of blood flow drawn from and returned to the peripheral vascular access. But it was only recently recognized that the line switch itself constitutes a dilution experiment for certain blood ...
Prado Manuel - - 2007
Emerging concepts in renal replacement therapies such as daily hemodialysis (HD) and wearable artificial kidney (WAK) meet the challenges derived from the aging of renal disease population. The successful results of blood recirculation to improve the dialysis clearance of medium-high uremic toxins suggest that this technique could be used both ...
Rafique Zahid - - 2007
Objective: To compare arteriovenous fistula recirculation by thermodilution technique and urea based two needle slow flow method. Design: Comparative cross-sectional study. Place and Duration of Study: Hemodialysis Unit of Nephrology Department of Shaikh Zayed Hospital, Lahore, from October 2005 to December 2005. Patients and Methods: Thirty one patients with end ...
Jaberi A - - 2007
PURPOSE: The creation of a vascular access is necessary in hemodialysis patients, including those with marginal vessels. Upper arm fistulae are attractive due to the ease of creation and of achieving high access flow rates. Cephalic arch stenosis (CAS) can lead to failure of upper arm fistulae and is increasingly ...
Donmez Ayhan - - 2007
We retrospectively evaluated 276 short-term femoral venous dialysis catheters (STFVCs) used for the collection of peripheral blood progenitor cells (PBPCs). Patients were not given any prophylactic antibiotic or anti-thrombotic therapy. Totally 877 leukapheresis sessions were performed. STFVCs were sufficient for continuous flow rate in all leukapheresis session. Side effects were ...
Gross M - - 2007
The measurement of ionic dialysance by conductivity variation is an established method in diffusive hemodialysis. To extend the validity of this method for use in highly convective therapies, such as online hemodiafiltration, we derived a new model for the measurement of ionic dialysance. This method was validated in a study ...
Tosun O - - 2007
BACKGROUND: Retrobulbar hemodynamic alterations can occur during hemodialysis sessions, and patients with chronic renal failure may experience visual problems. PURPOSE: To evaluate the effect of single-session hemodialysis on retrobulbar vessel hemodynamics by color Doppler ultrasonography. MATERIAL AND METHODS: Thirty-five patients were included in the study. Retrobulbar blood flows were examined ...
Lagali Neil S - - 2007
The diffuse reflection spectrum in the 500-1670 nm region for whole blood taken from healthy subjects and end-stage renal disease (ESRD) patients was measured to test the feasibility of optically monitoring ESRD and its treatment by hemodialysis. Spectral regions where optical absorption significantly differed between healthy subjects and ESRD patients ...
Zinovik Igor N - - 2007
A computational fluid dynamic (CFD) model was developed and used to simulate blood flow associated with our pulsating respiratory catheter. A principal goal of this CFD study was to evaluate how the balloon-generated flow permeated through the fiber bundle and interacted with the flow past the catheter. The simulation showed ...
Dasselaar Judith J - - 2007
Monitoring of relative blood volume changes (DeltaRBV) has been propagated for the prevention of hemodialysis hypotension. Although the influence of ultrafiltration volume on DeltaRBV is well-known, there is no mention in the literature that DeltaRBV results should be interpreted differently for the first, second, or third hemodialysis session of the ...
Schneditz Daniel - - 2007
The duration, accuracy, and reproducibility of a new access flow measuring technique was analyzed in a series of in vitro experiments using an extracorporeal line switch that allowed for almost instantaneous reversal of extracorporeal blood flow without disconnecting the blood lines. Access flow was modeled from the magnitude and time ...
Capodicasa E - - 2007
BACKGROUND: Isoprene, a volatile hydrocarbon produced by the human organism, is currently being extensively investigated because the mechanisms underlying its endogenous origin are unknown and because experiments suggest it is toxic and cancerogenous. Previous reports of increases in breath isoprene concentrations during 4-hour, thrice-weekly hemodialysis, but not during continuous ambulatorial ...
Thermann Florian - - 2007
BACKGROUND: Dialysis shunt-associated steal syndrome (DASS) is a rare complication of hemodialysis access (HA) which preferably occurs in brachial fistulas. Treatment options are discussed controversially. Aim of this study was to evaluate flow-controlled fistula banding. MATERIALS AND METHODS: Patients treated between 2002 and 2006 were included in this prospective survey. ...
Eloot Sunny - - 2007
BACKGROUND: To reduce infection risks in patients on hemodialysis with a long term central venous catheter, different types of closed luer lock access devices are used on the arterial and venous catheter hub. Although those connectors create a mechanically and microbiologically closed system in between two dialysis sessions, no data ...
Wijnen E - - 2007
A reduction in vascular access flow poses a risk for thrombosis. We present a new technique to measure vascular access flow during dialysis based on extracorporeal temperature gradients, and their changes, on reversing the extracorporeal bloodlines without having to inject an indicator. Fistula temperatures were measured by the blood temperature ...
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