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Results 251 - 300 of 1240
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Van Hoek Frank - - 2010
BACKGROUND: During haemodialysis, some patients experience intensification of symptoms of haemodialysis access-induced distal ischaemia. Aim of this study is to compare the effects of two different regimens of arterial blood flow in patients with an arteriovenous access. METHODS: A questionnaire identified 10 patients that subjectively experienced ischaemic symptoms during haemodialysis. ...
Oztürkmen Seda - - 2010
A 4-year-old boy with acute lymphoblastic leukemia (ALL) was inserted a central venous catheter into right vena jugularis interna, whereas on BFM-ALL (Protocol 1) therapy. He developed progressive anemia, thrombocytopenia, schistocytes with triangular or crescent shapes, microspherocytes and teardrop cells in the peripheric blood smear, elevated lactate dehydrogenase, and decreased ...
Castellarnau Alex - - 2010
Real-time determination of Kt/V can be provided by monitoring ultraviolet absorbance of solutes in spent dialysate. This not only overcomes dependency on error-prone pre- and post-dialysis blood sampling; it circumvents inaccuracies associated with estimating the urea distribution volume and its high measurement frequency tightly reflects the course of the dialysis. ...
Lindsay Robert M - - 2010
Measurement of blood flow rate (Qa) is used to monitor dialysis access, AV fistulas, and grafts. Indicator dilution measurements of the recirculation (R) induced by reversal of hemodialysis blood lines are commonly used. This plus the dialysis circuit flow (Qb) allows calculation of Qa. R also changes the conductivity, which ...
Bhimani Jai P - - 2010
Diffusive clearance depends on blood and dialysate flow rates and the overall mass transfer area coefficient (K(o)A) of the dialyzer. Although K(o)A should be constant for a given dialyzer, urea K(o)A has been reported to vary with dialysate flow rate possibly because of improvements in flow distribution. This study examined ...
Válek Martin - - 2010
The aim of this study was to investigate an association between vascular access blood flow (QVA), cardiac output(CO), and load of left ventricle (LLV) using a simple physical model calculation based on real data, specifically inpatients with high access blood flow arteriovenous fistula(AVF). Vascular access blood flow, CO, and peripheral ...
Shemesh David - - 2010
Dialysis-associated steal syndrome with rest pain and ischemic nonhealing ulcers dictates prompt surgical intervention. Distal revascularization with interval ligation is extensive surgery for frail patients in whom calcified distal arteries make anastomosis difficult. Simple banding is appropriate in high-flow fistulas. In low-flow accesses, further flow reduction by simple banding may ...
Meyer Jay J - - 2010
PURPOSE: To determine capsular breakage risk from contact by phacoemulsification needles by machine and tip type. DESIGN: Experimental laboratory investigation. METHODS: Infiniti (Alcon, Inc.) with Intrepid cartridges and Signature (Abbott Medical Optics, Inc.) phacoemulsification machines were tested using 19- and 20-gauge sharp and rounded tips. Actual and unoccluded flow vacuum ...
Santoro D - - 2010
Native arterio-venous fistula (AVF), is the first choice of the vascular access for hemodialysis treatment. In comparison with other vascular accesses such as prosthetic arterio-venous graft or permanent central venous catheter, AVF has shown a significant reduction in cardiovascular mortality. It needs, of course, an appropriate blood flow that provides ...
Hiremath Swapnil - - 2010
BACKGROUND: The incidence of congestive heart failure is 3-fold greater than that of acute coronary syndrome in haemodialysis (HD) patients. The purpose of this study was to determine if blood flow through an arteriovenous (AV) access contributes to an increase in left ventricular mass (LVM) that may increase the risk ...
Thomson Peter - - 2010
BACKGROUND: Central venous catheterization is a fundamental component in delivering haemodialysis yet is associated with significantly higher complication rates than other methods of vascular access. In this study, we report results of univariate and multivariate analyses designed to identify and quantify independent risk association for catheterization type, clinical variables and ...
Takatori M - - 2010
We developed an online continuous hemodiafiltration (CHDF) system with a central reverse osmosis (RO) fluid delivery system in 1996. This was improved to a system composed of a single-patient dialysis machine and RO module in 2003. This comprises a water treatment system, an RO module, a dialysis machine with 3 ...
Hudson Joanna Q - - 2010
Eptifibatide is a parenteral glycoprotein IIb-IIIa inhibitor that prevents platelet aggregation. Although contraindicated in dialysis patients due to limited safety and dialysis data, eptifibatide is prescribed in this population and is associated with bleeding complications. This study was done to determine dialysis clearance (CL(D)) of eptifibatide using an in vitro ...
Mistr?k Erik - - 2010
BACKGROUND: Cardiovascular mortality in hemodialysis (HD) patients remains high despite improvements in HD technique such as dialysis adequacy, dialysis fluid purity, and membrane biocompatibility. Optimal fluid balance to maintain optimal hemodynamic stability during hemodialysis (HD) procedure is essential. At the present time, hemodynamic stability is conventionally assessed as stability of ...
Maduell F - - 2010
Post-dilution on-line hemodiafiltration (OL-HDF) is the most efficient infusion mode to obtain maximum clearances of uremic toxins, with a recommended manual infusion flow (Qi) of 25% of the blood flow with the main limitation that causes alarms by hemoconcentration throughout the session. Recent technical advances allow automatic prescription of Qi ...
Szamosfalvi Balazs - - 2010
BACKGROUND: Large-scale adoption of regional citrate anticoagulation (RCA) is prevented by risks of the technique as practiced traditionally. Safe RCA protocols with automated delivery on customized dialysis systems are needed. METHODS: We applied kinetic analysis of solute fluxes during RCA to design a protocol for sustained low-efficiency dialysis (SLED) for ...
Shinozaki Koichiro - - 2010
Fulminant hepatic failure (FHF) can be described as a potentially fatal condition presenting with hepatic encephalopathy (HE) and coagulopathy associated with acute hepatic dysfunction, regardless of its etiology. Blood purification (BP) is expected to be effective against HE and coagulopathy in FHF. In this paper, we outline the objectives and ...
Eloot Sunny - - 2010
We compared three access flow (AF) monitoring techniques: blood dilution using ultrasound (US), blood temperature monitoring (BTM), and online clearance monitoring (OCM), and investigated the impact of dialyzer blood flow (Q(B)), measurement time point and patient's position. US, BTM and OCM were performed in 20 hemodialysis (HD) patients at Q(B)300. ...
Ding Weiping - - 2010
Hollow fiber modules are commonly used to conveniently and efficiently remove cryoprotective agents (CPAs) from cryopreserved cell suspensions. In this paper, a steady-state model coupling mass transfers across cell and hollow fiber membranes is theoretically developed to evaluate the removal of CPAs from cryopreserved blood using hollow fiber modules. This ...
Lim Ki Moo - - 2010
For blood purification systems using a semipermeable membrane, the convective mass transfer by ultrafiltration plays an important role in toxin removal. The increase in the ultrafiltration rate can improve the toxin removal efficiency of the device, ultimately reducing treatment time and cost. In this study, we assessed the effects of ...
du Cheyron Damien - - 2010
BACKGROUND/AIMS: Online monitoring devices for intermittent hemodialysis have been developed to improve intradialytic cardiovascular stability in chronic dialysis patients. We propose to test blood volume and blood temperature biofeedback control systems in critically ill patients with acute kidney injury (AKI). METHODS: Twenty patients were prospectively dialyzed with machines equipped with ...
Miguel Susana San - - 2009
AIM: The aim of the project is to determine the effectiveness of using online access flow measurement, thermodilution method (Fresenius BTM), in detecting and predicting thrombosis or stenosis of the haemodialysis fistula, so that early intervention could be instituted. METHODOLOGY: All haemodialysis patients with permanent vascular dialysis access, either arteriovenous ...
Saad Wael E A - - 2009
PURPOSE: To evaluate the feasibility of establishing a U-shaped inferior vena cava (IVC) catheter entirely from a transhepatic approach and to determine the catheter caliber that would provide adequate flow for hemodialysis. MATERIALS AND METHODS: Three pigs (weight, 45-50 kg) were used. A peripheral right hepatic vein was accessed transhepatically ...
Azar Ahmad Taher - - 2009
Clearance of urea depends on the dialysis solution flow rate as well. A faster dialysis solution flow rate increases the efficiency of diffusion of urea from blood to dialysate. An in vivo study was used in order to examine the effect of increasing dialysate flow rate (Q D ) on ...
Leonard Edward F - - 2009
Current efforts to prolong dialysis and make it ambulatory may, but need not, follow the established countercurrent contact of blood and dialysate through a membrane. Avoiding anticoagulation and addressing decremented performance of membranes used over long times suggests gentler blood contact and greatly reduced contact areas. This paper describes a ...
Ficheux Alain - - 2010
BACKGROUND: Urea kinetic modelling-based methods are widely used to assess dialysis efficacy. However, they require blood sampling and are susceptible to a number of errors, mainly from the calculated parameters (particularly V). Spent dialysate determinations have been used and have been shown to be reliable and simple to use. In ...
Klammt Sebastian - - 2009
Extracorporeal liver support procedures based on albumin dialysis require the use of pharmaceutical-grade human serum albumin (HSA). Those preparations contain octanoate, which is added as stabilizer during the production process. For octanoate, a direct involvement in the pathogenesis of liver failure complications as well as an indirect influence by competitive ...
Patel Jignes H - - 2009
BACKGROUND/AIMS: Telavancin is a lipoglycopeptide antimicrobial agent which has been approved in Europe and has been recently FDA approved in the United States. Telavancin's parenteral solution contains hydroxy propyl-beta -cyclodextrin (HP-beta -CD) to enhance its solubility. The disposition of telavancin and HP-beta -CD during continuous renal replacement therapies (CRRT ) ...
Maarek Jean-Michel I - - 2009
There is considerable interest in assessing cardiovascular function noninvasively in patients receiving hemodialysis. A possible approach is to measure the blood concentration of bolus-injected indocyanine green dye and to apply the dye-dilution method for estimating cardiac output and blood volume. Blood ICG concentration can be derived from a measurement of ...
Morel Hélène - - 2009
This paper proposes an in vitro hemodiafiltration (HDF) model in which the patient is represented by a 2 L bag of fresh heparinized bovine blood circulated by a 4008H monitor through a 0.6 m2 hemodialyzer to investigate kinetics of bicarbonate (HCO,) during online post-dilution HDF. Five tests were carried out, ...
Ergun Tarkan - - 2010
PURPOSE: The goal of the present study is to sonographically investigate the effects of hemodialysis on the hepatic and mesenteric circulation in end-stage renal disease (ESRD) patients on a regular-basis hemodialysis and compare with healthy subjects. MATERIALS AND METHODS: Twenty ESRD patients on regular hemodialysis and 20 control subjects were ...
Tuka Vladimir - - 2009
BACKGROUND: Vascular access is the lifeline for end-stage renal disease patients needing hemodialysis treatment. For dialysis treatment two needles are placed into the vascular access. Few studies on needle hemodynamics have been published. METHODS: We investigated needle hemodynamics by means of Doppler ultrasonography, both in B-mode and in pulsed Doppler ...
Borzou S R - - 2009
Inadequacy of dialysis is one of the determinants of morbidity and mortality in patients undergoing dialysis. The aim of this study was to assess the effect of increasing blood flow rate during hemodialysis (HD) on the adequacy of dialysis. In this study, 42 patients on maintenance HD were assessed. Body ...
Whittier William L - - 2009
Measurement of hemodialysis (HD) access flow (QA) is a noninvasive approach for arteriovenous graft or fistula surveillance. Flow dilution (FD) and in-line dialysance (DD) are two common methods for measuring QA. In a randomized fashion, we prospectively evaluated QA using FD and DD in 48 HD patients during three separate ...
Polaschegg Hans-Dietrich - - 2009
Blood damage is an unavoidable side effect of extracorporeal circulation. The effects of blood damage on patients' hematocrit and erythropoietin requirement as well as other potential side effects have not been studied for uneventful treatments. Comparing long nocturnal dialysis with regular 4-hour, three times per week dialysis allows for the ...
Thongboonkerd Visith - - 2010
Extracorporeal blood purification and peritoneal dialysis are widely used in renal replacement therapy for patients with end-stage renal disease (ESRD) and acute kidney injury (AKI). Additionally, extracorporeal blood purification can be used also for treatment of non-renal disorders to remove endogenous or exogenous toxins from the blood circulation. Efforts have ...
Yamamoto Ken-ichiro - - 2009
Dialyzer performance strongly depends on the flow of blood and dialysis fluid as well as membrane performance. It is necessary, particularly to optimize dialysis fluid flow, to develop a highly efficient dialyzer. The objective of the present study is to evaluate by computational analysis the effects of dialyzer jacket baffle ...
Davenport Andrew - - 2009
Intradialytic hypotension remains a frequent problem in routine outpatient hemodialysis. Although hypotension can be reduced by more frequent dialysis sessions and longer session duration, these options are not available for many patients. Advances in hemodialysis machine technology have led to the development of relative blood volume monitoring. However, multicenter trials ...
Kunikata Satoru - - 2009
Dialysis fluid flow and mass transfer rate of newly developed dialyzers were evaluated using mass transfer correlation equations of dialysis fluid-side film coefficient. Aqueous creatinine clearance and overall mass transfer coefficient for APS-15S (Asahi Kasei Kuraray) as a conventional dialyzer, and APS-15SA (Asahi Kasei Kuraray), PES-150Salpha (Nipro), FPX140 (Fresenius), and ...
Schneditz Daniel - - 2009
The classic assumption that a large fraction of blood creatinine remains sequestered within erythrocytes when blood is dialyzed has been challenged by recent observations where approximately 60% of erythrocyte water appeared accessible to diffusive creatinine transport during a dialyzer transit. This discrepancy provided the motivation to revisit and reanalyze the ...
van Hoek Frank - - 2009
A hemodialysis access may lead to cardiac overload (CO) or hand ischemia [hemodialysis access induced distal ischemia (HAIDI). Surgical banding restricts access flow and promotes distal perfusion. Aim of the study was to investigate short- and long-term clinical success of banding in these patient groups. After evaluation using a standard ...
Malík Jan - - 2009
BACKGROUND: Chronic heart failure is very common in hemodialyzed patients due to several factors such as intermittent volume overload, anemia, and hypertension. Dialysis access flow is usually considered to have a minor effect. We hypothesized that creation of dialysis access with "normal" flow would lead to elevation of B-type natriuretic ...
Manikandan Ramaswamy - - 2009
PURPOSE: We evaluated the flow characteristics of various 3-way catheters. MATERIALS AND METHODS: We evaluated 14, 3-way catheters, including 18Fr, 20Fr, 22Fr and 24Fr Rusch(R), 18Fr, 20Fr, 22Fr and 24Fr Bardex(R), 18Fr, 20Fr, 22Fr and 24Fr Dover, and 20Fr and 22Fr Mentor (Mentor, Santa Barbara, California) catheters. Ten operators applied ...
Schneditz Daniel - - 2009
BACKGROUND: Sequestration of creatinine, in both erythrocytes and other cells, has complicated the widespread application of creatinine kinetics in haemodialysis. The goal of this study was to determine whether creatinine kinetics could be described using a regional blood flow (RBF) model that also incorporated diffusion between intra- and extracellular fluids. ...
Kim Jeong Chul - - 2009
BACKGROUND/AIMS: Blood flow profiles in fiber bundles depend on the design of the arterial port and affects the biocompatibility of the hemodialyzer. We analyzed the effects of arterial port design on blood flow distribution in fiber bundles using nonintrusive imaging techniques. METHODS: The velocity fields in arterial ports and the ...
Gregory Martin C - - 2009
INTRODUCTION: Dialysis is an effective treatment for end-stage renal disease, but it is available to only approximately half of those who need it in the world. METHODS: Two prototype passive-flow dialysate delivery systems were constructed. RESULTS: Each dialysate delivery system provided a flow of dialysate in the range of 200-300 ...
Mineshima Michio - - 2009
In order to improve solute removal efficiency, several types of dialyzers with enhanced internal filtration (IF) were introduced for clinical applications. In these dialyzers, enhanced IF increased convective transport of the solute in addition to diffusive transport. Internal filtration-enhanced hemodialysis (IFEHD) defined as hemodialysis therapy using the enhanced IF dialyzer ...
Rostoker Guy - - 2009
It is widely believed that single-needle (SN) hemodialysis is inferior to conventional double-needle (DN) hemodialysis. The purpose of this study was to compare two SN dialysis regimens using different blood flow rates with conventional DN hemodialysis. The primary outcome measure was ionic dialysance. We studied eight patients (two women, six ...
Fleming Geoffrey M - - 2009
Etanercept is a tumor necrosis factor-alpha antagonist used in inflammation-mediated conditions. Continuous venovenous hemofiltration (CVVH) has also been used in patients with inflammatory conditions. This study evaluated etanercept clearance using an in vitro CVVH model. Etanercept clearance was assessed in vitro in bovine blood at 1-3 mg/l final serum concentration, ...
Moragianni Vasiliki A - - 2010
OBJECTIVE: To assess the effect of microscopic and macroscopic contamination of embryo transfer (ET) catheters with blood or mucus on in vitro fertilization (IVF)-ET success rates. DESIGN: Retrospective cohort study. SETTING: Infertility practice in teaching community hospital. PATIENT(S): Four hundred seventy patients undergoing IVF-ET. INTERVENTION(S): Controlled ovarian hyperstimulation and IVF-ET. ...
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