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Gao Feng - - 2013
Redox magnetohydrodynamics (MHD) is a promising technique for developing new electrochemical-based microfluidic flow devices with unique capabilities, such as easily switching flow direction, adjusting flow speeds and flow patterns as well as avoiding bubble formation. However, a detailed description of all the forces involved and predicting flow patterns in confined ...
Shastry Shamee - - 2013
BACKGROUND: The dedicated devices for blood irradiation are available only at a few centers in developing countries thus the irradiation remains a service with limited availability due to prohibitive cost. OBJECTIVE: To implement a blood irradiation program at our center using linear accelerator. MATERIALS AND METHODS: The study is performed ...
Ng Ronald - - 2013
BACKGROUND: A new version of international standard (ISO 15197) and CLSI Guideline (POCT12) with more stringent accuracy criteria are near publication. We evaluated the glucose test performance of the FreeStyle Precision Pro system, a new blood glucose monitoring system (BGMS) designed to enhance accuracy for point-of-care testing (POCT). METHODS: Precision, ...
Krajewski Stefanie - - 2013
Due to their antibacterial effects, the use of silver nanoparticles (AgNPs) in a great variety of medical applications like coatings of medical devices markedly increased in the last years. However, contact of blood with AgNPs may induce adverse effects thereby altering hemostatic functions. The objective of this study was to ...
Moog Rainer - - 2013
Two units of red blood cells (RBC) can be collected by modern apheresis devices. A short description of the collection process is given in the present review. Apheresis RBCs show improved functionality compared to RBCs collected by manual whole blood donation. Provided that double RBC donor eligibility criteria are respected, ...
Morris Michael J - - 2013
Managing blood loss in total hip arthroplasty (THA) minimizes complications and decreases cost. Tissue-sparing anterior supine intermuscular THA (ASI-THA) may offer a quicker recovery but increases blood loss and transfusion requirements. This double-blinded prospective study compared a bipolar sealer (Aquamantys 6.0 bipolar sealer) to standard monopolar electrocautery in reducing blood ...
Chueh Ju-Yu - - 2013
BACKGROUND AND PURPOSE: To evaluate the impact of proximal flow control on efficacy and safety of mechanical thrombectomy in an in vitro middle cerebral artery occlusion. METHODS: Three independent variables, including clot type, device (Merci Retriever, Solitaire FR, and Trevo devices), and use of a balloon guide catheter, were used ...
König Kai - - 2013
Background: Excessive ambient noise levels have been identified as a potential risk factor for adverse outcome in very preterm infants. Noise level measurements for continuous positive airway pressure (CPAP) devices demonstrated that these constantly exceed current recommendations. The use of high-flow nasal cannula (HFNC) as an alternative non-invasive ventilation modality ...
O'Shea Genevieve - - 2013
Ventricular assist devices provide therapeutic options for patients with severe heart failure who have exhausted available medical therapies. With restoration of organ perfusion with ventricular assist devices, the heart failure resolves and quality of life and functional status improve. The current generation of continuous-flow devices present novel challenges to the ...
Boeker Peter - - 2013
For olfactometric measurements in combination with gas chromatography a device is needed to split the GC effluent between the detector and the sniffing port. Fixed split ratios are obtained by simple flow splitters with appropriate restrictions towards the two outlets. Variable split ratios are possible with additional control flows. One ...
Guinn Nicole R - - 2013
BACKGROUND: Estimates of blood loss in the operating room are typically performed as a visual assessment by providers, despite multiple studies showing this to be inaccurate. Use of a less subjective measurement of blood loss such as direct measurement of the hemoglobin (Hb) mass lost from the surgical field may ...
Wu Qihua - - 2013
Microfluidic and nanofluidic devices have undergone rapid development in recent years. Functions integrated onto such devices provide lab-on-a-chip solutions for many biomedical, chemical, and engineering applications. In this paper, a lab-on-a-chip technique for direct visualization of the single- and two-phase pressure-driven flows in nano-scale channels was developed. The nanofluidic chip ...
Stewart William J - - 2013
The ability of fish to evade predators is central to the ecology and evolution of a diversity of species. However, it is largely unclear how prey fish detect predators in order to initiate their escape. We tested whether larval zebrafish (Danio rerio) sense the flow created by adult predators of ...
Ferrari Luca - - 2013
ABSTRACT. During extracorporeal circulation (ECC), blood is periodically sampled and analyzed to maintain the blood-gas status of the patient within acceptable limits. This protocol has well-known drawbacks that may be overcome by continuous monitoring. We present the characterization of a new pH sensor for continuous monitoring in ECC. This monitoring ...
Luo Zhong Hua - - 2013
Barium sulfate powder used for radiopacity of experimental blood clots (EBCs) for testing mechanical thrombectomy devices (MTD) has negative effects on EBCs mechanical properties. In vitro and in vivo exploration was performed to determine if the iodine based contrast medium will have less negative effects on the EBCs than barium. ...
Tian Yong Y Department of Chemistry and Biochemistry, University of Texas at Arlington, Arlington, TX 76019-0065, - - 2013
Deaths due to smoke inhalation in fires are often due to poisoning by HCN. Rapid administration of antidotes can result in complete resuscitation of the patient but judicious dosing requires the knowledge of the level of cyanide exposure. Rapid sensitive means for blood cyanide quantitation are needed. Hydroxocyanocobinamide (OH(CN)Cbi) reacts ...
Lee Jung-Jae - - 2013
Bacterial sepsis is a serious clinical condition that can lead to multiple organ dysfunction and death despite timely treatment with antibiotics and fluid resuscitation. We have developed an approach to clearing bacteria and endotoxin from the bloodstream, using magnetic nanoparticles (MNPs) modified with bis-Zn-DPA, a synthetic ligand that binds to ...
Tripathi Siddhartha - - 2013
In recent years, microfluidic chips have proven ideal tools for biochemical analysis, which, however, demands a unique and compatible plasma separation scheme. Various research groups have established continuous flow separation methods in microfluidic devices; however, they have worked with relatively small dimension microchannels (similar to the blood cell diameter). The ...
Dietrich Henry - - 2013
The purpose of this study was to show that acceptable blood samples can be collected through intravenous (IV) catheters. Hemolysis of blood samples and appropriate methods of blood sample collection can be a topic of controversy in an emergency department and throughout a hospital. This investigation was conducted by laboratory ...
Kellett-Gregory Lindsay M - - 2013
OBJECTIVE: To describe the use of automated blood salvage devices for autotransfusion in dogs. TECHNIQUE: Blood salvage devices can be used to collect blood from the intraoperative surgical field or postsurgical drainage sites. The salvage device washes cells in 0.9% saline, removing plasma proteins, other cellular components, and activators of ...
Stallard T - - 2013
It is well known that a wake will develop downstream of a tidal stream turbine owing to extraction of axial momentum across the rotor plane. To select a suitable layout for an array of horizontal axis tidal stream turbines, it is important to understand the extent and structure of the ...
Bedke Jens - - 2013
Ureterorenoscopy (URS) has revolutionized upper urinary tract stone therapy. However, the size of the working channel and the stone baskets limit irrigation flow as well as vision. This study determined further improvements of irrigation flow, deflection capacities and impairments of breaking resistance in a new 1.2 French (F) ultra-miniaturized basket. ...
Nagarsheth Nimesh P - - 2013
To determine whether cell salvage blood collection with a laparoscopic suction device is inferior to use of a traditional Yankauer suction device. Prospective, in vitro study. Academic teaching hospital. Individual units of donated packed red blood cells were diluted with normal saline solution to a hematocrit level of 21%. The blood ...
Kulinsky Lawrence - - 2013
This work reviews present technologies and developing trends in Point-of-Care (POC) microfluidic diagnostics platforms. First, various fluidics technologies such as pressure-driven flows, capillary flows, electromagnetically driven flows, centrifugal fluidics, acoustically driven flows, and droplet fluidics are categorized. Then three broad categories of POC microfluidic testing devices are considered: lateral flow ...
Yue Xiao-Yan - - 2013
Accurate and timely glucose monitoring is essential in intensive care units. Real-time continuous glucose monitoring system (CGMS) has been advocated for many years to improve glycemic management in critically ill patients. In order to determine the effect of calibration time on the accuracy of CGMS, real-time subcutaneous CGMS was used ...
Undar Akif - - 2013
Extracorporeal life support (ECLS) and mechanical circulatory support (MCS) have become indispensable treatment tools for pediatric patients with congenital heart defects undergoing peri-operative or end-stage heart and/or lung failure. ECLS and MCS can serve as bridges to recovery, transplantation (heart or lung), destination therapy, or "bridge to bridge" long-term MCS. ...
Nardini Giordano - - 2013
The presence of nucleated erythrocytes and thrombocytes in reptile blood limits the use of electronic cell-counting devices for leukocytes so that manual counting techniques and evaluation of blood smears are necessary, resulting in time-consuming procedures requiring good training and experience. The evaluation of most hematologic values is complicated by the ...
Kailasan Arunvel - - 2013
The heat generated during normal operation of an implantable Left Ventricular Assist Device (LVAD) can have a deleterious effect on the surrounding tissue as well as the blood flowing through the device. This effect is often overlooked and might also result in heart pump failure. Therefore, for a comprehensive design ...
Dragone Vincenza - - 2013
We present a study in which the versatility of 3D-printing is combined with the processing advantages of flow chemistry for the synthesis of organic compounds. Robust and inexpensive 3D-printed reactionware devices are easily connected using standard fittings resulting in complex, custom-made flow systems, including multiple reactors in a series with ...
Wójtowicz P - - 2013
Hydrodynamic flow regulators are used in environmental engineering as a replacement for traditional flow throttling devices. They are extremely efficient, reliable and free from the common disadvantages of traditional devices. Recent research by the authors indicated that the atomization of a liquid by hydrodynamic flow regulators accelerates oxygenation and may ...
Costa-da-Silva André Luis - - 2013
Aedes aegypti, the main vector of dengue virus, requires a blood meal to produce eggs. Although live animals are still the main blood source for laboratory colonies, many artificial feeders are available. These feeders are also the best method for experimental oral infection of Ae. aegypti with Dengue viruses. However, ...
Kasamoto Sawako - - 2013
The rodent micronucleus assay has been most widely and frequently used as a representative in vivo assay system to assess mutagenicity of chemicals, regardless of endpoint of mutagenicity. The micronucleus has been developed to assess induction of structural and numerical chromosomal aberrations of target chemical. In this chapter, we describe ...
Yoshikawa Takeki - - 2013
Medical staff members should match blood products with patients using a barcode authentication system for blood transfusion to prevent medical accidents. However, our hospital only verifies the blood products of the Japanese Red Cross Society and the preserved autologous blood, not the autologous blood salvaged during the operation or from ...
Seyler Helga - - 2013
There is an increasing demand for organic semiconducting materials with the emergence of organic electronic devices. In particular, large-area devices such as organic thin-film photovoltaics will require significant quantities of materials for device optimization, lifetime testing and commercialization. Sourcing large quantities of materials required for the optimization of large area ...
Klopp Rainer Christian - - 2013
Abstract As part of a placebo-controlled study, high-resolution measurement methods were used to examine, on the basis of representative functional characteristics of microcirculation, whether and to what extent six different, commercially available, physical treatment devices were suitable for influencing, through complementary therapy, deficient blood-flow regulation. Of the six commercially available ...
Lindner Gregor - - 2013
Trauma related haemorrhagic anaemia is rarely diagnosed by physical examination alone but typically includes measurement of blood haemoglobin, one of the most frequently ordered laboratory tests. Recently, noninvasive technologies have been developed that allow haemoglobin to be measured immediately without the need for intravenous access or having to take venous, ...
Lei Kin Fong - - 2013
Blood coagulation is an extremely complicated and dynamic physiological process. Monitoring of blood coagulation is essential to predict the risk of hemorrhage and thrombosis during cardiac surgical procedures. In this study, a high throughput microfluidic chip has been developed for the investigation of the blood coagulation process under temperature and ...
Hoyland Kimberley - - 2013
The risk of postoperative erectile dysfunction (ED) following radical prostatectomy (RP) is reported to be between 14% and 89%. With an increase in the detection of prostate cancer in younger men, there is a greater emphasis on the appropriate management of ED following RP. A number of options are available ...
Taylor David M - - 2013
Despite improved body armor, hemorrhage remains the leading cause of preventable death on the battlefield. Trauma to the junctional areas such as pelvis, groin, and axilla can be life threatening and difficult to manage. The Abdominal Aortic Tourniquet (AAT) is a prehospital device capable of preventing pelvic and proximal lower ...
Pfützner Andreas A IKFE-Institute for Clinical Research and Development, Parcusstr. 8, D-55116 Mainz, Germany. - - 2013
Accuracy of blood glucose readings is (among other things) dependent on the test strip being completely filled with sufficient sample volume. The devices are supposed to display an error message in case of incomplete filling. This laboratory study was performed to test the performance of 31 commercially available devices in ...
Pfützner Andreas A IKFE Services-Institute for Clinical Research and Development, D-55116 Mainz, Germany. - - 2013
Hematocrit (HCT) is known to be a confounding factor that interferes with many blood glucose (BG) measure-ment technologies, resulting in wrong readings. Dynamic electrochemistry has been identified as one possible way to correct for these potential deviations. The purpose of this laboratory investigation was to assess the HCT stability of ...
Pfützner Andreas A IKFE–Institute for Clinical Research and Development, Mainz, Germany. - - 2013
We performed a blood glucose meter hematocrit (HCT) interference test with lower sample manipulation requirements by using blood samples from patients with different blood glucose (BG) levels. Blood from five patients with different BG levels (2.8, 5.6, 8.3, 13.9, 19.4 mmol/liter) was manipulated to contain five different HCT concentrations (35/40/45/50/55%). ...
Ramljak Sanja S IKFE Institute for Clinical Research and Development, Mainz, - - 2013
Abnormal hematocrit levels may interfere with glucose readings of patient self-assessment blood glucose (BG) meters. The aim of this laboratory investigation was to assess the potential influence of hematocrit variations on a variety of BG meters applying different measurement technologies. Venous heparinized blood was manipulated to contain three different BG ...
Alvankarian Jafar J Institute of Microengineering and Nanoelectronics, Universiti Kebangsaan Malaysia, 43600 Bangi, Selangor, - - 2013
Our goal is to design, fabricate, and characterize a pillar-based microfluidic device for size-based separation of human blood cells on an elastomeric substrate with application in the low-cost rapid prototyping of lab-chip devices. The single inlet single outlet device is using parallel U-shape arrays of pillars with cutoff size of ...
Gong Max M MM Department of Mechanical and Industrial Engineering, University of Toronto, 5 King's College Road, Toronto, Ontario M5S 3G8, - - 2013
In this paper, we present a low cost and equipment-free blood filtration device capable of producing plasma from blood samples with mL-scale capacity and demonstrate its clinical application for hepatitis B diagnosis. We report the results of in-field testing of the device with 0.8-1 ml of undiluted, anticoagulated human whole blood ...
Jun Kang Yang Y Center for Biofluid and Biomimic Research, Pohang University of Science and Technology, Pohang, South - - 2013
Accurate measurement of blood viscoelasticity including viscosity and elasticity is essential in estimating blood flows in arteries, arterials, and capillaries and in investigating sub-lethal damage of RBCs. Furthermore, the blood viscoelasticity could be clinically used as key indices in monitoring patients with cardiovascular diseases. In this study, we propose a ...
Moon Hui-Sung HS In Vitro Diagnostics Lab, Bio Research Center, Samsung Advanced Institute of Technology, San 14, Nongseo-dong, Giheung-gu, Younin-si, Gyeonggi-do 446-712, South - - 2013
Circulating tumor cells (CTCs) are highly correlated with the invasive behavior of cancer; as such, the ability to isolate and quantify CTCs is of great biomedical importance. This research presents a multi-stage multi-orifice flow fractionation (MS-MOFF) device formed by combining three single-stage multi-orifice segments designed for separating breast cancer cells ...
Plutschack Matthew B MB Department of Chemistry and Biochemistry, Florida State University, Tallahassee, FL 32306, USA ; Max Planck Institute of Colloids and Interfaces, Am Mühlenberg 1, 14476 Potsdam, - - 2013
We describe the synthesis of 1-amino-2,5-anhydro-D-mannose ("mannitolamine"), a key intermediate to the 7-nitro-1,2,3-benzadiazole conjugate (NBDM), using commercially available fluidic devices to increase the throughput. The approach is the first example of a flow-based Tiffeneau-Demjanov rearrangement. Performing this step in flow enables a ~64-fold throughput enhancement relative to batch. The flow ...
Noeth Nadine - - 2013
For devices such as bio-/chemical sensors in microfluidic systems, flow fluctuations result in noise in the sensor output. Here, we demonstrate in-line monitoring of flow fluctuations with a cantilever-like sensor integrated in a microfluidic channel. The cantilevers are fabricated in different materials (SU-8 and SiN) and with different thicknesses. The ...
Borges Boniek Castillo - - 2013
This study aimed to evaluate whether preheated resin-based flowable restoratives would show increased hardness and softening susceptibility after an early cariogenic challenge. Fluroshield- Yellowed, Bioseal, Wave, Master Flow, Fluroshield-White, Conseal F, Filtek Z350 Flow, and Opallis Flow were tested. Preheating was performed using a microwave device. Five specimens of each ...
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