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Yakubu Sani Ibn - - 2013
An interaction between device resistance and inhalation flow provides the 'energy' to de-aggregate the metered dose of a dry powder inhaler (DPIs). Hence all dry powder inhalers demonstrate flow dependent dose emission but information on this at low flows is not available. We have adapted the compendial method for the ...
Nielsen Vance G - - 2013
Replacement of key components of the circulatory system with artificial devices has become the mainstay of therapy for conditions such as end-stage valvular disease or congestive heart failure. Unfortunately, device thrombosis and thromboembolic morbidity persist despite optimized anticoagulation. This work reviews the commonly known causes of device-associated thrombophilia, introduces recent ...
Lima-Oliveira Gabriel - - 2013
In vitro diagnostic tests play a key role in patients' management (e.g., guiding red blood cell transfusions). The aim of this study was to evaluate the impact of an innovative device (Buzzy(®)) which is claimed to be able to relieve venipuncture pain by means of cold and vibration. This device ...
Ambrisko T D - - 2013
A spirometry device equipped with mainstream CO2 /flow sensor is not available for large animal anaesthesia. To measure the resistance of a new large animal spirometry device and assess its agreement with reference methods for volume measurements. In vitro experiment and cross-over study using anaesthetised horses. A flow partitioning device ...
Nam Jeonghun - - 2013
Malaria is a serious disease that threatens the public health, especially in developing countries. Various methods have been developed to separate malaria-infected RBCs (i-RBCs) from blood samples for clinical diagnosis and biological and epidemiological researches. In this study, we propose a simple and label-free method for separating not only late-stage ...
Wiegmann Bettina - - 2013
Combined acute lung injury (ALI) and kidney injury (AKI) is a common problem in critically ill patients. By combining pulmonary (gas exchange) and renal (hemofiltration) support in one extracorporeal device with low-flow resistance, we seek to provide less artificial surfaces maintaining sufficient organ support. Modified Interventional Lung Assist (iLA) Membrane ...
Holmes Martin S - - 2013
Morbidity and mortality rates of chronic respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD) are rising. There is a strong requirement for more effective management of these chronic diseases. Dry powder inhalers (DPIs) are one kind of devices currently employed to deliver medication aimed at controlling asthma ...
Tsuruoka N - - 2013
Concentrations of biological substances are useful as indicators of physiological and pathological states. In order to monitor biological substances in daily life, we developed a minimally invasive needle type device with which biological substances are extracted through a microperfusion system inserted under the skin. The perfusion needle has a flow ...
Suzurikawa Jun - - 2013
Individuals with spinal cord injuries often experience thermoregulation disorders as well as sensory and motor disabilities. In order to prevent such individuals from becoming hyperthermic, we developed a body heat removal system (BHRS) with thermoelectric devices. Our BHRS comprises four Peltier devices mounted on a wheelchair backrest and continuously transfers ...
Grandjean-Thomsen Nicolas - - 2013
Obstructive Sleep Apnoea (OSA) is a prevalent disease. Reliable estimation of respiratory parameters by devices used to treat OSA is important for therapy initiation and maintenance. This is achieved by estimating patient flow in the presence of inadvertent leak from the total flow measured by the device. A method of ...
Sapkota Achyut - - 2013
Monitoring of thrombogenic process is very important in ventricular assistance devices (VADs) used as temporary or permanent measures in patients with advanced heart failure. Currently, there is a lack of a system which can perform a real-time monitoring of thrombogenic activity. Electrical signals vary according to the change in concentration ...
Haward S J SJ Faculdade de Engenharia da Universidade do Porto, Centro de Estudos de Fenómenos de Transporte, Rua Dr. Roberto Frias, 4200-465 Porto, - - 2013
We utilize a recently developed microfluidic device, the Optimized Shape Cross-slot Extensional Rheometer (OSCER), to study the elongational flow behavior and rheological properties of hyaluronic acid (HA) solutions representative of the synovial fluid (SF) found in the knee joint. The OSCER geometry is a stagnation point device that imposes a ...
Li Lizi - - 2013
Recent research on the use of bioactive paper for human blood typing has led to the discovery of a new method for identifying the haemagglutination of red blood cells (RBCs). When a blood sample is introduced onto paper treated with the grouping antibodies, RBCs undergo haemagglutination with the corresponding grouping ...
Nollet Kenneth E - - 2013
Twenty-first century demand for radio spectrum continues to increase with the explosive growth of wireless devices, but authorities reserve slices of the spectrum for licensed Amateur Radio operators, recognizing their value to the public, particularly with respect to providing emergency communications. Blood banking and transfusion medicine are among the specialties ...
Gordon Zachary L - - 2013
Reducing perioperative blood loss and transfusion requirements is important in the operative treatment of idiopathic scoliosis. This can be achieved with special frames, cell saver systems, pharmacologic aspects, and other techniques. Recently there has been interest in bipolar sealer devices as an adjunct to traditional monopolar electrocautery. However, there is ...
Noiphung Julaluk - - 2013
Electrochemical paper-based analytical devices (ePADs) with integrated plasma isolation for determination of glucose from whole blood samples have been developed. A dumbbell shaped ePAD containing two blood separation zones (VF2 membranes) with a middle detection zone was fabricated using the wax dipping method. The dumbbell shaped device was designed to ...
Del Rosal Blanca - - 2013
Thermal loading effects in flow-through electroporation microfluidic devices have been systematically investigated by using dye-based ratiometric luminescence thermometry. Fluorescence measurements have revealed the crucial role played by both the applied electric field and flow rate on the induced temperature increments at the electroporation sections of the devices. It has been ...
Gunaydin Serdar - - 2013
PURPOSE: The performance characteristics and clinical outcome of a novel hemoconcentrator, the HemoSep (Brightwake, Nottingham, United Kingdom), for reusing salvaged blood postoperatively were evaluated. DESCRIPTION: HemoSep concentrates blood by removing the fluid component from a pooled volume of blood salvaged at the end of the operation from the heart-lung machine. ...
Maji Debashis - - 2013
Development of micro-fabrication technology, along with an ever increasing demand for reliable, low cost clinical health care has led to the realization of various BioMEMS devices. Present study aims at developing a flexible flow sensor on polymer substrate to monitor real-time blood flow and determine plague formation satisfying sensitivity, biocompatibility, ...
Kadkhoda Ghamsari Ali - - 2013
Bucky gel is a gelatinous mixture of carbon nanotubes and an ionic liquid. This mixture was employed in fabrication of a low-voltage, rapid, and dry electroactive bimorph actuator: Bucky Gel Actuator (BGA). Feasibility studies were carried out on BGA to evaluate its potential application as a new interface for flow ...
Wittmann Andreas - - 2013
BACKGROUND: Protection against needlestick injuries has significantly improved in recent years thanks to so-called "safety devices." However, a potential drawback occasionally reported by users is a risk of blood splashing. If this blood comes in contact with the mucous membranes, it could lead to an infection. METHODS: Five safety peripheral ...
Wittrock J A M - - 2013
The purpose of this study was to evaluate the diagnostic performance of a hand-held electronic glucometer (Precision Xtra; Abbott Diabetes Care Inc., Mississauga, ON, Canada) for cow-side use in dairy cattle. This device has been validated for measuring blood concentrations of β-hydroxybutyrate in dairy cows. This study was designed to ...
Li Tingjie - - 2013
Lab-on-a-CD, as a main branch of Lab-on-a-chip technology, has led to several very successful commercial products. Most of these existing Lab-on-a-CD systems present complex system designs and thus are relatively expensive. In this work, we have developed a simple but robust Lab-on-a-CD system for parallel whole blood analyses. This Lab-on-a-CD ...
Bond Meaghan - - 2013
Anemia affects a quarter of the world's population, and a lack of appropriate diagnostic tools often prevents treatment in low-resource settings. Though the HemoCue 201+ is an appropriate device for diagnosing anemia in low-resource settings, the high cost of disposables ($0.99 per test in Malawi) limits its availability. We investigated ...
Goh Yuhan A - - 2013
Aqueous based controlled decoration of platinum nanoparticles on plasma treated carbon nano-onions (CNOs) occurs within the shear flow generated by a vortex fluidic device (VFD), using ascorbic acid as the reducing agent, with the electrocatalytic potential of the resulting Pt-NPs@CNOs nano-composites demonstrated.
Morshuis Michiel M Clinic for Heart, Thoracic and Cardiovascular Surgery, Heart and Diabetes Centre NRW, Ruhr University Bochum, Bad Oeynhausen, - - 2013
In patients with acute heparin-induced thrombocytopenia (HIT) needing urgent cardiac surgery, bivalirudin is recommended as a first-line strategy for intraoperative anticoagulation. However, due to the unique elimination process of bivalirudin, careful adjustment of the perfusion and surgical strategy is mandatory as blood stasis in the circuit or prolonged interruption of ...
Neely Lori A - - 2013
Candida spp. cause both local and disseminated infections in immunocompromised patients. Bloodstream infections of Candida spp., known as "candidemia," are associated with a high mortality rate (40%), which is mainly attributed to the long diagnostic time required by blood culture. We introduce a diagnostic platform based on T2 magnetic resonance ...
Dewhirst Elisabeth - - 2013
BACKGROUND: In recent years, the continuous noninvasive hemoglobin measurement has been offered by devices using advanced pulse oximetry technology. Accuracy has been established in healthy adults as well as in surgical and intensive care unit patients but not in the setting of acute hemorrhage. In this study, we evaluated the ...
Barlinn Kristian - - 2013
BACKGROUND AND PURPOSE: We aimed to evaluate safety and tolerability of a novel operator-independent ultrasound device among stroke-free volunteers. METHODS: A headframe containing 18 ultrasound transducers (each operating at 2 MHz, pulsed-wave) was used to expose both temporal windows and the suboccipital window. The transmission characteristics were set to emulate ...
Gao Feng F Department of Chemistry and Biochemistry, University of Arkansas, Fayetteville, Arkansas 72701, United - - 2013
Redox magnetohydrodynamics (MHD) is a promising technique for developing new electrochemical-based microfluidic flow devices with unique capabilities, such as easily switching flow direction and adjusting flow speeds and flow patterns as well as avoiding bubble formation. However, a detailed description of all the forces involved and predicting flow patterns in ...
Thorausch Kristin - - 2013
BACKGROUND: Donor granulocyte concentrates are routinely administered to patients with granulocyte function defects or transient neutropenia and (risk of) bacterial or fungal exacerbations, despite lack of definitive clinical proof for patient-relevant outcome improvement. Granulocytes are collected by apheresis from healthy donors treated with granulocyte-colony-stimulating factor and/or steroids for neutrophil mobilization ...
Zhao Guanjia - - 2013
Catalytic microjet bubble-propelled engines have attracted a large amount of interest for their potential applications in biomedicine, environmental sciences and natural resources discovery. One of the current efforts in this field is focused on the search of biocompatible fuels. However, only a minimal amount of effort has been made to ...
Zhang Zheng - - 2013
Assembled polydimethylsiloxane microfluidic devices were modified with a sulfobetaine polymer through continuous "tip-to-tip" modification, significantly reducing blood clotting and extending device patency under blood flow. This technology can be designed to enable the development of devices that can continuously work in whole blood, especially in an extracorporeal or in vivo ...
Smallwood Craig D - - 2013
Background: Gas exchange monitoring by indirect calorimetry (IC) during noninvasive ventilation (NIV) is desirable but currently not available. Leaks around the mask preclude reliable measurements of carbon dioxide production (VCO2) and oxygen consumption (VO2) in this population. We aimed to examine the impact of system leaks and gas flows on ...
Shastry Shamee - - 2013
BACKGROUND: The dedicated devices for blood irradiation are available only at a few centers in developing countries thus the irradiation remains a service with limited availability due to prohibitive cost. OBJECTIVE: To implement a blood irradiation program at our center using linear accelerator. MATERIALS AND METHODS: The study is performed ...
Ng Ronald - - 2013
BACKGROUND: A new version of international standard (ISO 15197) and CLSI Guideline (POCT12) with more stringent accuracy criteria are near publication. We evaluated the glucose test performance of the FreeStyle Precision Pro system, a new blood glucose monitoring system (BGMS) designed to enhance accuracy for point-of-care testing (POCT). METHODS: Precision, ...
Krajewski Stefanie - - 2013
Due to their antibacterial effects, the use of silver nanoparticles (AgNPs) in a great variety of medical applications like coatings of medical devices markedly increased in the last years. However, contact of blood with AgNPs may induce adverse effects thereby altering hemostatic functions. The objective of this study was to ...
Moog Rainer - - 2013
Two units of red blood cells (RBC) can be collected by modern apheresis devices. A short description of the collection process is given in the present review. Apheresis RBCs show improved functionality compared to RBCs collected by manual whole blood donation. Provided that double RBC donor eligibility criteria are respected, ...
Morris Michael J - - 2013
Managing blood loss in total hip arthroplasty (THA) minimizes complications and decreases cost. Tissue-sparing anterior supine intermuscular THA (ASI-THA) may offer a quicker recovery but increases blood loss and transfusion requirements. This double-blinded prospective study compared a bipolar sealer (Aquamantys 6.0 bipolar sealer) to standard monopolar electrocautery in reducing blood ...
Chueh Ju-Yu - - 2013
BACKGROUND AND PURPOSE: To evaluate the impact of proximal flow control on efficacy and safety of mechanical thrombectomy in an in vitro middle cerebral artery occlusion. METHODS: Three independent variables, including clot type, device (Merci Retriever, Solitaire FR, and Trevo devices), and use of a balloon guide catheter, were used ...
König Kai - - 2013
Background: Excessive ambient noise levels have been identified as a potential risk factor for adverse outcome in very preterm infants. Noise level measurements for continuous positive airway pressure (CPAP) devices demonstrated that these constantly exceed current recommendations. The use of high-flow nasal cannula (HFNC) as an alternative non-invasive ventilation modality ...
O'Shea Genevieve - - 2013
Ventricular assist devices provide therapeutic options for patients with severe heart failure who have exhausted available medical therapies. With restoration of organ perfusion with ventricular assist devices, the heart failure resolves and quality of life and functional status improve. The current generation of continuous-flow devices present novel challenges to the ...
Boeker Peter - - 2013
For olfactometric measurements in combination with gas chromatography a device is needed to split the GC effluent between the detector and the sniffing port. Fixed split ratios are obtained by simple flow splitters with appropriate restrictions towards the two outlets. Variable split ratios are possible with additional control flows. One ...
Guinn Nicole R - - 2013
BACKGROUND: Estimates of blood loss in the operating room are typically performed as a visual assessment by providers, despite multiple studies showing this to be inaccurate. Use of a less subjective measurement of blood loss such as direct measurement of the hemoglobin (Hb) mass lost from the surgical field may ...
Wu Qihua - - 2013
Microfluidic and nanofluidic devices have undergone rapid development in recent years. Functions integrated onto such devices provide lab-on-a-chip solutions for many biomedical, chemical, and engineering applications. In this paper, a lab-on-a-chip technique for direct visualization of the single- and two-phase pressure-driven flows in nano-scale channels was developed. The nanofluidic chip ...
Stewart William J - - 2013
The ability of fish to evade predators is central to the ecology and evolution of a diversity of species. However, it is largely unclear how prey fish detect predators in order to initiate their escape. We tested whether larval zebrafish (Danio rerio) sense the flow created by adult predators of ...
Ferrari Luca - - 2013
ABSTRACT. During extracorporeal circulation (ECC), blood is periodically sampled and analyzed to maintain the blood-gas status of the patient within acceptable limits. This protocol has well-known drawbacks that may be overcome by continuous monitoring. We present the characterization of a new pH sensor for continuous monitoring in ECC. This monitoring ...
Luo Zhong Hua - - 2013
Barium sulfate powder used for radiopacity of experimental blood clots (EBCs) for testing mechanical thrombectomy devices (MTD) has negative effects on EBCs mechanical properties. In vitro and in vivo exploration was performed to determine if the iodine based contrast medium will have less negative effects on the EBCs than barium. ...
Tian Yong Y Department of Chemistry and Biochemistry, University of Texas at Arlington, Arlington, TX 76019-0065, - - 2013
Deaths due to smoke inhalation in fires are often due to poisoning by HCN. Rapid administration of antidotes can result in complete resuscitation of the patient but judicious dosing requires the knowledge of the level of cyanide exposure. Rapid sensitive means for blood cyanide quantitation are needed. Hydroxocyanocobinamide (OH(CN)Cbi) reacts ...
Lee Jung-Jae - - 2013
Bacterial sepsis is a serious clinical condition that can lead to multiple organ dysfunction and death despite timely treatment with antibiotics and fluid resuscitation. We have developed an approach to clearing bacteria and endotoxin from the bloodstream, using magnetic nanoparticles (MNPs) modified with bis-Zn-DPA, a synthetic ligand that binds to ...
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