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He Jie - - 2013
Hydrodynamic flow in a microfluidic (MF) device offers a high-throughput platform for the continuous and controllable self-assembly of amphiphiles. However, the role of hydrodynamics on the assembly of colloidal amphiphiles (CAMs) is still not well understood. This article reports a systematic study of the assembly of CAMs, which consist of ...
Badr Bouchra - - 2013
Regularly monitoring blood flow through a vascular access (Qa) can predict a dysfunction and dramatically reduce the number of thromboses. The aim of our study was to compare two integrated access flow devices, thermodilution (Qa-BTM: BTM®, Fresenius Medical Care, Bad Homburg, Germany) and ionic dialysance (Qa-ID: OCM®, Fresenius Medical Care, ...
Basey-Fisher Toby H - - 2013
The non-destructive ex vivo determination of haemoglobin (Hgb) concentration offers the capability to conduct multiple red blood cell haematological measurements on a single sample, an advantage that current optical techniques are unable to offer. Here, a microwave method and device for the accurate and non-destructive determination of Hgb concentration in ...
Davidson Edward H - - 2013
The mechanotransduction mechanisms linking distraction device activation to new bone formation remain unknown. We hypothesize that the tension stress of activation during distraction osteogenesis is transmitted through lacunocanalicular fluid flow to initiate the osteogenic signaling cascade. Adult Sprague-Dawley rats (N = 24) were subjected to mandibular osteotomy and application of ...
Derman Peter B - - 2013
Blood conservation with saline-coupled bipolar sealing devices in primary total knee arthroplasty (TKA) has had mixed results. Moreover, investigators have not studied these devices in infected TKA cases in which conventional methods of blood management cannot be used. We conducted a single-surgeon, case-control study to evaluate how the choice of ...
Liang Jinyang - - 2013
A cross-correlation-based method is proposed to quantitatively measure transverse flow velocity using optical resolution photoacoustic (PA) microscopy enhanced with a digital micromirror device (DMD). The DMD is used to alternately deliver two spatially separated laser beams to the target. Through cross-correlation between the slow-time PA profiles measured from the two ...
Mut Fernando - - 2013
Quantifying the hemodynamic environment within aneurysms and its change after deployment of flow diverting devices is important to assess the device efficacy and understand their long-term effects. The purpose of this study was to estimate deviations in the quantification of the relative change of hemodynamic variables during flow diversion treatment ...
Boeker Peter - - 2013
The Deans'switch is an effluent switching device based on control flows of carrier gas instead of mechanical valves in the analytical flow path. This technique promises high inertness and a wear-free operation. Recently new monolithic microfluidic devices have become available. In these devices the whole flow system is integrated into ...
Korczyk Piotr M - - 2013
We present microfluidic modules (traps) that allow us to lock, shift, dose and merge micro-aliquots of liquid precisely. The precision is hard-wired into the geometry of the device: small values of the capillary number guarantee reproducibility of operation over a range of rates of flow that need not be controlled ...
Stemple C Christopher - - 2013
A novel smartphone-based detection device was created to detect infectious pathogens directly from diluted (10%) human whole blood. The model pathogen was histidine-rich protein 2 (HRP-2), an antigen specific to Plasmodium falciparum (malaria). Anti-HRP-2-conjugated submicrobeads were mixed with HRP-2-infused 10% blood in a lab-on-a-chip device. The white LED flash and ...
Nollet Kenneth E - - 2013
Twenty-first century demand for radio spectrum continues to increase with the explosive growth of wireless devices, but authorities reserve slices of the spectrum for licensed Amateur Radio operators, recognizing their value to the public, particularly with respect to providing emergency communications. Blood banking and transfusion medicine are among the specialties ...
Saunders Ashley B - - 2013
A left-to-right shunting muscular ventricular septal defect (VSD) was diagnosed in a 4-month-old, female, 1.8 kg Bichon Frise - poodle mix dog. Echocardiographic evidence of cardiac remodeling, calculated pulmonary blood flow (Qp) to systemic blood flow (Qs) ratio of 2.8, and radiographic evidence of pulmonary edema supported the diagnosis of a ...
Foinard A - - 2013
Stopping and restarting carrier fluid flow and performing simultaneous drug infusions can lead to hazardous disturbances in drug delivery. The present study was designed to assess in vitro whether using a multi-lumen infusion access device could prevent noradrenaline disturbances. In vitro laboratory work. Two infusion devices were studied: a standard ...
Warwick D - - 2013
Aim: Different mechanical devices for thromboprophylaxis have different flow characteristics. A new device (Vadoplex) has been developed to provide a short impulse around the calf, a concept derived from the efficacy of foot impulse technology. New devices should be compared with existing devices to establish whether it has a comparable ...
Yang Chin-Lung - - 2013
Point-of-care diagnostics (POCD) for blood coagulation benefit patients on-site, but available POCD devices are too expensive to be affordable in many countries. Optically based methodologies are cheap and reliable, and have been exploited in bench-top coagulometers to monitor coagulation with plasma, but not whole blood, which contains cellular components that ...
Yasmin Lyzu - - 2013
A vortex fluidic device (VFD) involving a rapidly rotating tube open at one end forms dynamic thin films at high rotational speed for finite sub-millilitre volumes of liquid, with shear within the films depending on the speed and orientation of the tube. Continuous flow operation of the VFD where jet ...
Yakubu Sani Ibn - - 2013
An interaction between device resistance and inhalation flow provides the 'energy' to de-aggregate the metered dose of a dry powder inhaler (DPIs). Hence all dry powder inhalers demonstrate flow dependent dose emission but information on this at low flows is not available. We have adapted the compendial method for the ...
Nielsen Vance G - - 2013
Replacement of key components of the circulatory system with artificial devices has become the mainstay of therapy for conditions such as end-stage valvular disease or congestive heart failure. Unfortunately, device thrombosis and thromboembolic morbidity persist despite optimized anticoagulation. This work reviews the commonly known causes of device-associated thrombophilia, introduces recent ...
Lima-Oliveira Gabriel - - 2013
In vitro diagnostic tests play a key role in patients' management (e.g., guiding red blood cell transfusions). The aim of this study was to evaluate the impact of an innovative device (Buzzy(®)) which is claimed to be able to relieve venipuncture pain by means of cold and vibration. This device ...
Ambrisko T D - - 2013
A spirometry device equipped with mainstream CO2 /flow sensor is not available for large animal anaesthesia. To measure the resistance of a new large animal spirometry device and assess its agreement with reference methods for volume measurements. In vitro experiment and cross-over study using anaesthetised horses. A flow partitioning device ...
Nam Jeonghun - - 2013
Malaria is a serious disease that threatens the public health, especially in developing countries. Various methods have been developed to separate malaria-infected RBCs (i-RBCs) from blood samples for clinical diagnosis and biological and epidemiological researches. In this study, we propose a simple and label-free method for separating not only late-stage ...
Wiegmann Bettina - - 2013
Combined acute lung injury (ALI) and kidney injury (AKI) is a common problem in critically ill patients. By combining pulmonary (gas exchange) and renal (hemofiltration) support in one extracorporeal device with low-flow resistance, we seek to provide less artificial surfaces maintaining sufficient organ support. Modified Interventional Lung Assist (iLA) Membrane ...
Holmes Martin S - - 2013
Morbidity and mortality rates of chronic respiratory diseases such as asthma and chronic obstructive pulmonary disease (COPD) are rising. There is a strong requirement for more effective management of these chronic diseases. Dry powder inhalers (DPIs) are one kind of devices currently employed to deliver medication aimed at controlling asthma ...
Tsuruoka N - - 2013
Concentrations of biological substances are useful as indicators of physiological and pathological states. In order to monitor biological substances in daily life, we developed a minimally invasive needle type device with which biological substances are extracted through a microperfusion system inserted under the skin. The perfusion needle has a flow ...
Suzurikawa Jun - - 2013
Individuals with spinal cord injuries often experience thermoregulation disorders as well as sensory and motor disabilities. In order to prevent such individuals from becoming hyperthermic, we developed a body heat removal system (BHRS) with thermoelectric devices. Our BHRS comprises four Peltier devices mounted on a wheelchair backrest and continuously transfers ...
Grandjean-Thomsen Nicolas - - 2013
Obstructive Sleep Apnoea (OSA) is a prevalent disease. Reliable estimation of respiratory parameters by devices used to treat OSA is important for therapy initiation and maintenance. This is achieved by estimating patient flow in the presence of inadvertent leak from the total flow measured by the device. A method of ...
Sapkota Achyut - - 2013
Monitoring of thrombogenic process is very important in ventricular assistance devices (VADs) used as temporary or permanent measures in patients with advanced heart failure. Currently, there is a lack of a system which can perform a real-time monitoring of thrombogenic activity. Electrical signals vary according to the change in concentration ...
Haward S J SJ Faculdade de Engenharia da Universidade do Porto, Centro de Estudos de Fenómenos de Transporte, Rua Dr. Roberto Frias, 4200-465 Porto, - - 2013
We utilize a recently developed microfluidic device, the Optimized Shape Cross-slot Extensional Rheometer (OSCER), to study the elongational flow behavior and rheological properties of hyaluronic acid (HA) solutions representative of the synovial fluid (SF) found in the knee joint. The OSCER geometry is a stagnation point device that imposes a ...
Li Lizi - - 2013
Recent research on the use of bioactive paper for human blood typing has led to the discovery of a new method for identifying the haemagglutination of red blood cells (RBCs). When a blood sample is introduced onto paper treated with the grouping antibodies, RBCs undergo haemagglutination with the corresponding grouping ...
Nollet Kenneth E - - 2013
Twenty-first century demand for radio spectrum continues to increase with the explosive growth of wireless devices, but authorities reserve slices of the spectrum for licensed Amateur Radio operators, recognizing their value to the public, particularly with respect to providing emergency communications. Blood banking and transfusion medicine are among the specialties ...
Gordon Zachary L - - 2013
Reducing perioperative blood loss and transfusion requirements is important in the operative treatment of idiopathic scoliosis. This can be achieved with special frames, cell saver systems, pharmacologic aspects, and other techniques. Recently there has been interest in bipolar sealer devices as an adjunct to traditional monopolar electrocautery. However, there is ...
Noiphung Julaluk - - 2013
Electrochemical paper-based analytical devices (ePADs) with integrated plasma isolation for determination of glucose from whole blood samples have been developed. A dumbbell shaped ePAD containing two blood separation zones (VF2 membranes) with a middle detection zone was fabricated using the wax dipping method. The dumbbell shaped device was designed to ...
Del Rosal Blanca - - 2013
Thermal loading effects in flow-through electroporation microfluidic devices have been systematically investigated by using dye-based ratiometric luminescence thermometry. Fluorescence measurements have revealed the crucial role played by both the applied electric field and flow rate on the induced temperature increments at the electroporation sections of the devices. It has been ...
Gunaydin Serdar - - 2013
PURPOSE: The performance characteristics and clinical outcome of a novel hemoconcentrator, the HemoSep (Brightwake, Nottingham, United Kingdom), for reusing salvaged blood postoperatively were evaluated. DESCRIPTION: HemoSep concentrates blood by removing the fluid component from a pooled volume of blood salvaged at the end of the operation from the heart-lung machine. ...
Maji Debashis - - 2013
Development of micro-fabrication technology, along with an ever increasing demand for reliable, low cost clinical health care has led to the realization of various BioMEMS devices. Present study aims at developing a flexible flow sensor on polymer substrate to monitor real-time blood flow and determine plague formation satisfying sensitivity, biocompatibility, ...
Page Catherine - - 2013
Anaemia is associated with inferior outcomes in critically ill patients. It is difficult to prevent and is treated commonly with the transfusion of packed red cells. However, transfusion to augment oxygen delivery has not been shown to consistently offer a survival advantage when the haemoglobin concentration exceeds 7 g/dL. Several ...
Kadkhoda Ghamsari Ali - - 2013
Bucky gel is a gelatinous mixture of carbon nanotubes and an ionic liquid. This mixture was employed in fabrication of a low-voltage, rapid, and dry electroactive bimorph actuator: Bucky Gel Actuator (BGA). Feasibility studies were carried out on BGA to evaluate its potential application as a new interface for flow ...
Wittmann Andreas - - 2013
BACKGROUND: Protection against needlestick injuries has significantly improved in recent years thanks to so-called "safety devices." However, a potential drawback occasionally reported by users is a risk of blood splashing. If this blood comes in contact with the mucous membranes, it could lead to an infection. METHODS: Five safety peripheral ...
Wittrock J A M - - 2013
The purpose of this study was to evaluate the diagnostic performance of a hand-held electronic glucometer (Precision Xtra; Abbott Diabetes Care Inc., Mississauga, ON, Canada) for cow-side use in dairy cattle. This device has been validated for measuring blood concentrations of β-hydroxybutyrate in dairy cows. This study was designed to ...
Li Tingjie - - 2013
Lab-on-a-CD, as a main branch of Lab-on-a-chip technology, has led to several very successful commercial products. Most of these existing Lab-on-a-CD systems present complex system designs and thus are relatively expensive. In this work, we have developed a simple but robust Lab-on-a-CD system for parallel whole blood analyses. This Lab-on-a-CD ...
Bond Meaghan - - 2013
Anemia affects a quarter of the world's population, and a lack of appropriate diagnostic tools often prevents treatment in low-resource settings. Though the HemoCue 201+ is an appropriate device for diagnosing anemia in low-resource settings, the high cost of disposables ($0.99 per test in Malawi) limits its availability. We investigated ...
Goh Yuhan A - - 2013
Aqueous based controlled decoration of platinum nanoparticles on plasma treated carbon nano-onions (CNOs) occurs within the shear flow generated by a vortex fluidic device (VFD), using ascorbic acid as the reducing agent, with the electrocatalytic potential of the resulting Pt-NPs@CNOs nano-composites demonstrated.
Morshuis Michiel - - 2013
In patients with acute heparin-induced thrombocytopenia (HIT) needing urgent cardiac surgery, bivalirudin is recommended as a first-line strategy for intraoperative anticoagulation. However, due to the unique elimination process of bivalirudin, careful adjustment of the perfusion and surgical strategy is mandatory as blood stasis in the circuit or prolonged interruption of ...
Neely Lori A - - 2013
Candida spp. cause both local and disseminated infections in immunocompromised patients. Bloodstream infections of Candida spp., known as "candidemia," are associated with a high mortality rate (40%), which is mainly attributed to the long diagnostic time required by blood culture. We introduce a diagnostic platform based on T2 magnetic resonance ...
Dewhirst Elisabeth - - 2013
BACKGROUND: In recent years, the continuous noninvasive hemoglobin measurement has been offered by devices using advanced pulse oximetry technology. Accuracy has been established in healthy adults as well as in surgical and intensive care unit patients but not in the setting of acute hemorrhage. In this study, we evaluated the ...
Barlinn Kristian - - 2013
BACKGROUND AND PURPOSE: We aimed to evaluate safety and tolerability of a novel operator-independent ultrasound device among stroke-free volunteers. METHODS: A headframe containing 18 ultrasound transducers (each operating at 2 MHz, pulsed-wave) was used to expose both temporal windows and the suboccipital window. The transmission characteristics were set to emulate ...
Thorausch Kristin - - 2013
BACKGROUND: Donor granulocyte concentrates are routinely administered to patients with granulocyte function defects or transient neutropenia and (risk of) bacterial or fungal exacerbations, despite lack of definitive clinical proof for patient-relevant outcome improvement. Granulocytes are collected by apheresis from healthy donors treated with granulocyte-colony-stimulating factor and/or steroids for neutrophil mobilization ...
Zhao Guanjia - - 2013
Catalytic microjet bubble-propelled engines have attracted a large amount of interest for their potential applications in biomedicine, environmental sciences and natural resources discovery. One of the current efforts in this field is focused on the search of biocompatible fuels. However, only a minimal amount of effort has been made to ...
Zhang Zheng - - 2013
Assembled polydimethylsiloxane microfluidic devices were modified with a sulfobetaine polymer through continuous "tip-to-tip" modification, significantly reducing blood clotting and extending device patency under blood flow. This technology can be designed to enable the development of devices that can continuously work in whole blood, especially in an extracorporeal or in vivo ...
Smallwood Craig D - - 2013
Background: Gas exchange monitoring by indirect calorimetry (IC) during noninvasive ventilation (NIV) is desirable but currently not available. Leaks around the mask preclude reliable measurements of carbon dioxide production (VCO2) and oxygen consumption (VO2) in this population. We aimed to examine the impact of system leaks and gas flows on ...
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