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Simpson Katharine M KM Department of Veterinary Clinical Sciences, Center for Veterinary Health Sciences, Oklahoma State University, Stillwater, OK - - 2014
Objective-To evaluate whether pedal bacteremia develops following regional IV perfusion (RIVP) of a 2% lidocaine hydrochloride solution in cattle with deep digital sepsis (DDS) and to determine which bacterial pathogens are most commonly isolated from the pedal circulation. Design-Prospective observational cohort study. Animals-9 adult cattle with DDS in 10 limbs ...
Silverstein Deborah C DC Department of Clinical Studies, Matthew J. Ryan Veterinary Hospital, University of Pennsylvania, Philadelphia, PA - - 2014
Objective-To assess the microcirculatory effects of IV fluid administration in healthy anesthetized dogs undergoing elective ovariohysterectomy. Animals-49 client-owned dogs. Procedures-Dogs were sedated, and anesthesia was induced with propofol and diazepam and maintained with isoflurane in oxygen. Dogs received lactated Ringer's solution (LRS) IV at rates of 0, 10, or 20 ...
Dunn Wendy J WJ Intensive Care Unit, Royal Melbourne Hospital, Melbourne, VIC. - - 2014
To examine the effects of patient and treatmentrelated variables on filter lifespan in critically ill adults receiving continuous renal replacement therapy (CRRT). This was a single-centre, retrospective, observational study conducted in a tertiary referral centre in metropolitan Melbourne, Australia. All CRRT filters used over a 44-month period from 1 January ...
De Kesel Pieter M M PM Laboratory of Toxicology, Faculty of Pharmaceutical Sciences, Ghent University, Ottergemsesteenweg 460, 9000, Ghent, - - 2014
Although dried blood spot (DBS) sampling is increasingly receiving interest as a potential alternative to traditional blood sampling, the impact of hematocrit (Hct) on DBS results is limiting its final breakthrough in routine bioanalysis. To predict the Hct of a given DBS, potassium (K(+)) proved to be a reliable marker. ...
Storry Jill R JR Division of Hematology and Transfusion Medicine, Department of Laboratory Medicine, Lund University, Lund, Sweden; Clinical Immunology and Transfusion Medicine, Laboratory Medicine, Office of Medical Services, Lund, - - 2014
Discrepancies in ABO grouping arise due to different reasons, posing a threat to patient safety. Underlying causes include mixed-field agglutination after transfusion, chimerism, fetomaternal exchange, or inheritance of unusual alleles resulting in weak A/B antigen expression. Cord blood from the infant of a group A2 B mother typed as group ...
Kildey Katrina K Research and Development, Australian Red Cross Blood Service, Brisbane, Australia; Faculty of Health, Queensland University of Technology, Brisbane, - - 2014
Transfusion of blood components has been associated with poor patient outcomes and, an overall increase in morbidity and mortality. Differences in the blood components arising from donor health, age and immune status may impact on outcomes of transfusion and transfusion-related immune modulation in recipients. The aim of this study was ...
Bennett Mj M Department of Cardiothoracic Anaesthesia, South West Cardiothoracic Centre, Plymouth, UK - - 2014
To determine the influence of haemodilution, bypass flow rates and calculated oxygen delivery during cardiopulmonary bypass (CPB) with either a conventional CPB (C-CPB) circuit or a miniaturised (Mini-CPB) circuit on cerebral oxygen desaturation. The effect of minimal haemodilution with a Mini-CPB was investigated. Eighty patients scheduled for elective cardiac surgery. ...
Hussain Shabneez S Section of Hematology, Department of Pathology, Microbiology, The Aga Khan University Hospital Karachi, Pakistan. Electronic address: - - 2014
This audit was conducted as a part of a quality assurance activity to assess the frequency of receiving completely filled out blood transfusion reaction forms which were accompanied by the required samples. Once this information is known, we will elevate the bar each year to achieve 100% compliance. The sub-aim ...
Igbokwe Nanacha Afifi - - 2014
Abstract Background: Heparinised blood was exposed to osmotic lysis in hypotonic buffered saline to evaluate erythrocyte membrane stability. When K3 EDTA blood was used, it added more to the ionic content of blood than heparin. The influence of suspending media's ionic strength on the osmotic stability of Sahel goat erythrocytes ...
Jang B B Sydney Knee Specialists, Edgecliff, NSW, - - 2014
PURPOSE. To evaluate the effect of intra-articular tranexamic acid (TXA) on blood loss after total knee arthroplasty (TKA). METHODS. Medical records of 73 men and 93 women (mean age, 68 years) who underwent primary TKA for osteoarthritis and received intra-articular TXA 1500 mg (n=56) or 3000 mg (n=56) or not ...
Wei Wei W Department of Orthopaedic, The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, - - 2014
The objective of this study was to determine whether topical tranexamic acid (TXA) carried similar hemostatic effect compared with intravenous TXA in total hip arthroplasty (THA). Three hundred and three THA patients were enrolled and randomized into 3 groups: no TXA group, topical and intravenous TXA group. The results showed ...
Guerci Philippe P 1Department of Anesthesiology and Critical Care Medicine, University Hospital Nancy, Vandoeuvre-Lès-Nancy, France. 2Department of Anesthesiology and Obstetric Critical Care Unit, Maternity Hospital, Nancy, France. 3Faculty of Medicine, University of Lorraine, Vandoeuvre-Lès-Nancy, - - 2014
To determine the regional cerebral oxygen saturation of hemoglobin (rcSO2) in severe preeclamptic parturients exhibiting neurologic symptoms compared with healthy pregnant women (control) and to describe the effects of MgSO4 infusion on rcSO2 and cerebral and systemic hemodynamic variables. Prospective, observational study. Obstetric critical care unit in a university-affiliated hospital. ...
Hasin Tal T Divisions of Cardiovascular Diseases*, Cardiothoracic Surgery†, Department of Anesthesiology§ and Department of Health Sciences Research‡ Mayo Clinic, USA. Division of Cardiac Surgery University Hospitals Case Medical Center, - - 2014
Cardiac output (CO) assessment is important in treating patients with heart failure. Durable left ventricular assist devices (LVAD) provide essentially all CO. In currently used LVADs estimated device flow is generated by a computerized algorithm. However LVAD flow estimate may be inaccurate in tracking true cardiac output. We correlated LVAD ...
Kanto-Nishimaki Yuko Y Department of Forensic Medicine, The Jikei University School of Medicine, Tokyo, Japan. Electronic address: - - 2014
Few large-scale investigations have looked at the oxyhemoglobin ratio (%O2-Hb) or the carboxyhemoglobin ratio (%CO-Hb) in fatal hypothermia and death by fire as applicable to forensic medicine. We therefore retrospectively examined right and left cardiac blood samples for both %O2-Hb and %CO-Hb in 690 forensic autopsy cases. We therefore sought ...
Jackson Mary L ML Department of Veterinary Medicine and Surgery, University of Missouri College of Veterinary Medicine, 900 East Campus Drive, Columbia, MO, - - 2014
To establish reference intervals for whole blood and plasma colloid osmotic pressure (COP) in healthy cats between the ages of 1 and 10 years using a cage-side colloid osmometer. Prospective, observational study. University veterinary teaching hospital. Sixty-three healthy cats. Phlebotomy. Whole blood COP mean was 24.4 (±2.78) mmHg and plasma ...
Egginton S S School of Biomedical Sciences, University of - - 2014
Dr Olga Hudlická, Professor Emeritus in the Department of Physiology, University of Birmingham Medical School, died suddenly on 3(rd) May not long after a fall. She was one of the best-known vascular physiologists of the last century, investigating control of blood flow and regulation of angiogenesis in skeletal and cardiac ...
Shih Andre C AC Departments of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL - - 2014
Objective-To assess the accuracy of an ultrasound velocity dilution cardiac output (UDCO) method, compared with that of the lithium dilution cardiac output (LiDCO) method, for determination of cardiac output (CO) in juvenile horses with experimentally induced hypovolemia. Animals-12 anesthetized 2- to 6-month-old horses. Procedures-For each anesthetized horse, CO was determined ...
M'baya B B Malawi Blood Transfusion Service, Blantyre, - - 2014
In 2009 Malawi introduced a new protocol to screen potential blood donors for anaemia, using the WHO Haemoglobin Colour Scale (HCS) for initial screening. Published studies of the accuracy of the HCS to screen potential blood donors show varying levels of accuracy and opinion varies whether this is an appropriate ...
Zhang Dan-Dan DD Department of Pediatric Dentistry, School of Stomatology, China Medical University, Shenyang, - - 2014
In regenerative endodontic treatment (RET) for immature permanent tooth, better treatment results could be obtained by applying platelet-rich plasma (PRP) as the scaffold rather than the blood clot. The goal of this study was to compare the histologic differences between using PRP and blood clot in RET. Three 6-month-old beagles ...
Hashimoto Shuichi S Research Center for Odontology, Tokyo, Japan. Electronic address: - - 2014
Epinephrine potentiates and prolongs the efficacy of local anesthetics by reducing blood flow. We investigated the effect of epinephrine on the pharmacokinetics of lidocaine and the pulpal blood volume after maxillary infiltration anesthesia in rats. We measured the (14)C-radioactivity and (14)C-distribution in the maxilla and the dental pulp after the ...
Hochwald Ori O Neonatal Intensive Care Unit, Rambam Medical Center, Haifa, - - 2014
To determine the relationship between left ventricular cardiac output (LVCO), superior vena cava (SVC) flow, and brain injury during whole-body therapeutic hypothermia. Sixteen newborns with moderate or severe hypoxic-ischemic encephalopathy were studied using echocardiography during and immediately after therapeutic hypothermia. Measures were also compared with 12 healthy newborns of similar ...
Wells Scott M SM New England Animal Medical Center, 595 W Center St, West Bridgewater, MA - - 2014
Objective-To determine whether measurement of blood cardiac troponin I (cTnI) concentrations with a cage-side analyzer could be used to differentiate cardiac from noncardiac causes of dyspnea in cats. Design-Prospective, multicenter study. Animals-44 client-owned cats with dyspnea and 37 healthy staff-owned cats. Procedures-Affected cats were examined because of dyspnea; treatment was ...
Carlier Jérémy J Laboratoire LAT LUMTOX, 800 av. Marie Curie, Z.I. Jean Jaurès, 07800 La Voulte-sur-Rhône, - - 2014
In March 2009, the body of a 51-year-old man was found in the boot of his car. The body had been frozen before being dismembered at the abdomen. The autopsy failed to determine the cause of death. Systematic toxicological analyses of the victim's peripheral blood and urine showed the presence ...
Waldén Katarina K Department of Cardiothoracic Surgery, Sahlgrenska University Hospital, Gothenburg, - - 2014
Data from small selected patient populations suggest that the preoperative plasma concentration of fibrinogen influences postoperative blood loss and red blood cell transfusion after cardiac operations, but there are also conflicting reports. We assessed the importance of preoperative fibrinogen concentration for excessive bleeding and red cell blood transfusion in a ...
Midgett Madeline M Department of Biomedical Engineering and Knight Cardiovascular Institute, Center for Developmental Health, Oregon Health and Science University Portland, OR, - - 2014
Embryonic heart formation results from a dynamic interplay between genetic and environmental factors. Blood flow during early embryonic stages plays a critical role in heart development, as interactions between flow and cardiac tissues generate biomechanical forces that modulate cardiac growth and remodeling. Normal hemodynamic conditions are essential for proper cardiac ...
Lindberg Lars L 1Department of Anesthesia and Intensive Care, Children's Hospital, Pediatric Intensive Care Unit, University Hospital of Lund, Lund, Sweden. 2Department of Pediatric Cardiac Surgery, Children's Hospital, University Hospital of Lund, Lund, - - 2013
To validate cardiac output measurements by ultrasound dilution technology (COstatus monitor) against those obtained by a transit-time ultrasound technology with a perivascular flow probe and to investigate ultrasound dilution ability to estimate pulmonary to systemic blood flow ratio in children. Prospective observational clinical trial. Pediatric cardiac operating theater in a ...
Henriksen Otto M - - 2013
Although both impaired cardiac function and reduced cerebral blood flow are associated with ageing, current knowledge of the influence of cardiac function on resting cerebral blood flow (CBF) is limited. The aim of this study was to investigate the potential effects of cardiac function on CBF. CBF and cardiac output ...
Gielen Chantal - - 2013
Fibrinogen concentrate is increasingly used in cardiac surgery when bleeding is anticipated or ongoing. Since randomized clinical studies to support this are lacking, it is relevant to know whether lower fibrinogen levels are associated with excessive bleeding. We performed a systematic review and meta-analysis to define the association between fibrinogen ...
Robbins Dan - - 2013
The purpose of this study was to investigate the physiological changes of the cardiovascular system in response to whole body vibration during quiet standing and identify whether there is a greater influence on the central or peripheral cardiovascular system. Twenty healthy participants (12 male and 8 female) were assessed over ...
Noori Shahab - - 2013
To investigate whether changes in cardiac function and cerebral blood flow (CBF) precede the occurrence of peri/intraventricular hemorrhage (P/IVH) in extremely preterm infants. In this prospective observational study, 22 preterm infants (gestational age 25.9 ± 1.2 weeks; range 23-27 weeks) were monitored between 4 and 76 hours after birth. Cardiac ...
Downing Tacy E TE Division of Cardiology and Department of Radiology, The Children's Hospital of Philadelphia, PA; and Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, - - 2013
Cardiac catheterization is routinely used as a diagnostic tool in single ventricle patients with superior cavopulmonary connection. This physiology presents inherent challenges in applying the Fick principle to estimate flow. We sought to quantitatively define the error in oximetry-derived flow parameters using phase-contrast cardiac MRI (CMR) as a reference. Thirty ...
Costa Isabel - - 2013
Tramadol is a widely used analgesic opioid for moderate-to-severe pain due to its efficacy and safety. Although tramadol induces less adverse effects compared with other opioids, an increased number of documented cases of dependence, abuse, intentional overdose or intoxication have been described. In fatal intoxication, the interpretation of the probable ...
Ambrisko T D - - 2013
/st>In a previous in vitro study using saline medium, the authors showed that certain drugs changed the voltages of lithium dilution cardiac output (LiDCO) sensors and also influenced their accuracy in measuring lithium concentrations. These two parameters correlated and so we examined whether such drug-sensor interaction exists when LiDCO sensor ...
Leslie A T F S - - 2013
Objective:To characterize and investigate the relationship between systemic blood flow and pre- and postoperative cerebral electrical activity in preterm neonates undergoing patent ductus arteriosus (PDA) ligation.Study design:A prospective observational study was conducted in 17 preterm neonates undergoing PDA ligation. All infants had amplitude-integrated electroencephalography (aEEG) recorded continuously from 4 h preoperatively ...
Juhl-Olsen Peter - - 2013
Ultrasonographic evaluation of the inferior vena cava (IVC) provides information on central hemodynamics and predicts fluid responsiveness during positive pressure ventilation. In spontaneously breathing patients, the correlations between IVC dynamics and the hemodynamic response to volume shifts remain to be described. We aimed to describe the correlation between IVC dynamics ...
Kohl Zachary F - - 2013
Amphibian pulmonary and systemic vascular circuits are arranged in parallel, with potentially important consequences for resistance (R) to blood flow. The contribution of the parallel anatomic arrangement to total vascular R (R T), independent of blood viscosity, is unknown. We measured pulmonary (R P) and systemic (R S) vascular R ...
Born Silvia - - 2013
Four-dimensional MRI is an in vivo flow imaging modality that is expected to significantly enhance the understanding of cardiovascular diseases. Among other fields, 4D MRI provides valuable data for the research of cardiac blood flow and with that the development, diagnosis, and treatment of various cardiac pathologies. However, to gain ...
Hansen Lasse Bremholm - - 2013
The 33 amino acid peptide hormone GLP-2 is produced by enteroendocrine L-cells, the density of which is highest in the ileum and the colon, in response to the presence of nutrients in the lumen. The biological effect of GLP-2 is mediated by activation of a G-protein-coupled 7-transmembrane receptor. GLP-2 receptors ...
Nakajima Kenichi - - 2013
Steel is not elemental iron, but rather a group of iron-based alloys containing many elements, especially chromium, nickel, and molybdenum. Steel recycling is expected to promote efficient resource use. However, open-loop recycling of steel could result in quality loss of nickel and molybdenum and/or material loss of chromium. Knowledge about ...
Whitney Gina - - 2013
AIM: The goal of this project is to measure the impact of standardization of transfusion practice on blood product utilization and postoperative bleeding in pediatric cardiac surgery patients. BACKGROUND: Transfusion is common following cardiopulmonary bypass (CPB) in children and is associated with increased mortality, infection, and duration of mechanical ventilation. ...
Born Silvia - - 2012
4D MRI is an in vivo flow imaging modality that is expected to significantly enhance the understanding of cardiovascular diseases. Among other fields, 4D MRI provides valuable data for the research of cardiac blood flow and with that the development, diagnosis, and treatment of various cardiac pathologies. However, to gain ...
Christensen Tine N - - 2012
Objective. Patients with cirrhosis often present with an abnormal distribution of blood volume with a reduced central blood volume (CBV) and central circulation time (CCT). In this group of patients it is important to determine the central haemodynamics as accurately as possible. The purpose of the present study was to ...
Crescenzi Giuseppe - - 2012
Abstract  Blood transfusion carries benefits and risks. Adult cardiac surgery accounts for a significant proportion of all red blood cells transfusions. However, the identification of the patient, who will truly benefit from transfusions, is still controversial. This review provides an overview on allogenic blood transfusions in adult cardiac surgery. (J ...
Li Peng - - 2012
During cardiac development, the cardiac wall and flowing blood are two important cardiac tissues that constantly interact with each other. This dynamic interaction defines appropriate biomechanical environment to which the embryonic heart is exposed. Quantitative assessment of the dynamic parameters of wall tissues and blood flow is required to further ...
Kobayashi Mariko - - 2012
Cleveland Clinic's continuous-flow total artificial heart has one motor and one rotating assembly supported by a hydrodynamic bearing. The right hydraulic output is self regulated by passive axial movement of the rotating assembly to balance itself with the left output. The purpose of this article is to present progress in ...
Yuki Koichi - - 2012
BACKGROUND:Although the traditional surgical approach for left hypoplastic heart syndrome is to perform staged, palliative procedures as a single ventricle lesion, certain anatomical subsets of patients are candidates for a 2-ventricle repair either as a primary or as a staged procedure. The pulmonary blood flow (Q(P))/systemic blood flow (Q(S)) range ...
Kobayashi Daisuke - - 2012
We report a neonate with left congenital diaphragmatic hernia and severe left ventricular dysfunction, in whom the blood flow in the transverse arch and its branches was supported in a retrograde fashion by patent ductus arteriosus. There was only minimal antegrade flow across the aortic valve and hemodynamic physiology resembled ...
Aoyama Kunihiro - - 2012
To detect symptomatic hemispheres during the postoperative course of subarachnoid haemorrhage (SAH) using arterial spin labelling (ASL). Eighteen patients with aneurysmal SAH were included; four exhibited symptomatic vasospasm postoperatively. All patients underwent ASL on days 9-10 (single time-point ASL). Nine patients underwent serial measurements of ASL (serial ASL) on days ...
Gade John - - 2012
ABSTRACT Objectives: Bronchial artery revascularization in lung transplantation is disputed. This study examined the physiological consequences of porcine bronchial transsection and reanastomosis with and without bronchial artery blood supply with relation to lung transplantation. Design: Translational, controlled animal study. Twelve pigs were operated through a left lateral thora-cotomy. The left ...
Jacobus Joanna - - 2012
The effects of adolescent marijuana use on the developing brain remain unclear, despite its prevalence. Arterial spin labeling (ASL) is a noninvasive imaging technique that characterizes neurovascular status and cerebral blood flow (CBF), potentially revealing contributors to neuropathological alterations. No studies to date have looked at CBF in adolescent marijuana ...
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