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Petersen Anja S AS Danish Headache Center, Department of Neurology, Glostrup Hospital, University of Copenhagen, - - 2014
Our aim was to review the existing literature to document oxygen's therapeutic effect on cluster headache. A PubMed search resulted in 28 hits, and from these and their references we found in total 11 relevant studies. We included six studies that investigated the efficacy of oxygen treatment. One study is ...
Voicu Sebastian S 1Medical and Toxicological Intensive Care Department, Lariboisière University Hospital, APHP, Paris, France. 2INSERM U942, Université Paris Diderot, Paris, France. 3Cardiology Department, Lariboisière University Hospital, APHP, Paris, France. 4Department of Anesthesiology and Critical Care, CHU Bicêtre, APHP, Le Kremlin-Bicêtre, France. 5INSERM U705, Université Paris Denis Diderot, Paris, France. 6Department of Anaesthesia and Intensive care, Lariboisière University Hospital, APHP, Paris, France. 7SAMU 75 and Department of Anesthesiology, Necker Hospital, APHP, Paris Descartes University, Medical School, Paris, France. 8Biochemical Laboratory, Lariboisière University Hospital, APHP, Paris, - - 2014
In patients treated with therapeutic hypothermia after out-of-hospital cardiac arrest, two blood gas management strategies are used regarding the PaCO2 target: α-stat or pH-stat. We aimed to compare the effects of these strategies on cerebral blood flow and oxygenation. Prospective observational single-center crossover study. ICU of University hospital. Twenty-one therapeutic ...
De Georgia Michael A MA Case Western Reserve University School of Medicine, Neurological Institute, University Hospitals Case Medical Center, Cleveland, OH, - - 2014
Brain injury results from ischemia, tissue hypoxia, and a cascade of secondary events. The cornerstone of neurocritical care management is optimization and maintenance of cerebral blood flow (CBF) and oxygen and substrate delivery to prevent or attenuate this secondary damage. New techniques for monitoring brain tissue oxygen tension (PtiO2) are ...
Kuliga Katarzyna Z KZ Human Development & Health, Faculty of Medicine, University of Southampton, - - 2014
We have evaluated the dynamics of skin microvascular blood flow (BF) and tissue oxygenation parameters (OXY) measured simultaneously at the same site using a combined non-invasive BF+OXY+temperature probe. Skin BF, oxygenated (oxyHb) and deoxygenated (deoxyHb) haemoglobin and mean oxygen saturation (SO2 ) were measured in 50 healthy volunteers at rest ...
De Vis J B JB Department of Radiology, University Medical Centre Utrecht, HP E 01.132, P.O. Box 85500, 3508GA, Utrecht, The Netherlands. Electronic address: - - 2014
Brain oxygen consumption reflects neuronal activity and can therefore be used to investigate brain development or neuronal injury in neonates. In this paper we present the first results of a non-invasive MRI method to evaluate whole brain oxygen consumption in neonates. For this study 51 neonates were included. The T1 ...
Weenink R P RP Diving Medical Center, Royal Netherlands Navy, PO Box 1000, 1780 CA, Den Helder, The Netherlands; Laboratory of Experimental Intensive Care and Anaesthesiology (L.E.I.C.A.), Department of Anaesthesiology, Academic Medical Center, University of Amsterdam, PO Box 22660, 1100 DD, Amsterdam, The Netherlands. Electronic address: - - 2014
Cerebral air emboli occur as a complication of invasive medical procedures. The sensitivity of cerebral monitoring methods for the detection of air emboli are not known. This study investigates the utility of electroencephalography and non-invasively measured cerebral oxygen saturation in the detection of intracerebrovascular air. In 12 pigs oxygen saturation ...
Tarumi Takashi T Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, TX, USA Department of Internal Medicine, Alzheimer's Disease Center, University of Texas Southwestern Medical Center, Dallas, TX, - - 2014
Background: Vascular disease and dysfunction are associated with the higher risk of Alzheimer's disease hypothetically due to cerebral hypoperfusion. Brain perfusion is protected by cerebral autoregulation, which, under normal conditions, maintains a constant cerebral blood flow and brain tissue oxygenation. Objective: To determine whether dynamic regulation of cerebral blood flow ...
Belohlavek J J 2Department of Internal Medicine, Cardiovascular Medicine, General University Hospital in Prague, Prague, Czech - - 2014
The adequacy of cerebral blood flow and the level of regional oxygen saturation during CPR and early post-resuscitation phases assuring favorable neurological outcome are not known. We demonstrate the feasibility of cerebral blood flow and oxygenation monitoring by a continuous transcranial Doppler combined with cerebral oximetry in a patient with ...
Gramer M M Max-Planck-Institute of Neurological Research, Gleueler Str. 50, 50825 Cologne, Germany. Electronic address: - - 2014
Brain function critically relies on the supply with energy substrates (oxygen and glucose) via blood flow. Alterations in energy demand as during neuronal activation induce dynamic changes in substrate fluxes and blood flow. To study the complex system that regulates cerebral metabolism requires the combination of methods for the simultaneous ...
Andrewartha Sarah Jane SJ - - 2014
Marsupial joeys are born ectothermic and develop endothermy within their mother's thermally stable pouch. We hypothesised that tammar wallaby joeys would switch from α-stat to pH-stat regulation during the transition from ectothermy to endothermy. To address this, we compared ventilation (VE), metabolic rate (VO2) and variables relevant to blood gas ...
Sørensen Henrik H Department of Anaesthesia, The Copenhagen Muscle Research Centre, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark; Zürich Centre for Integrative Human Physiology, University of Zürich, Zürich, - - 2014
Frontal lobe oxygenation (Sc O2 ) is assessed by spatially resolved near-infrared spectroscopy (SR-NIRS) although it seems influenced by extra-cerebral oxygenation. We aimed to quantify the impact of extra-cerebral oxygenation on two SR-NIRS derived Sc O2 . Multiple regression analysis estimated the influence of extra-cerebral oxygenation as exemplified by skin ...
Dunaev A V AV Photonics and Nanoscience Group, Division of Physics, School of Engineering, Physics and Mathematics, University of Dundee, Dundee DD1 4HN, UK. State University-Education-Science-Production Complex, Scientific-Educational Center of 'Biomedical Engineering', Oryol 302020, - - 2014
Multi-functional laser non-invasive diagnostic systems allow the study of a number of microcirculatory parameters, including index of blood microcirculation (Im) (by laser Doppler flowmetry, LDF) and oxygen saturation (StO2) of skin tissue (by tissue reflectance oximetry, TRO). This research aimed to use such a system to investigate the synchronization of ...
Sedlacik Jan J Neuroradiology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. Electronic address: - - 2014
The non-invasive assessment of (patho-)physiological parameters such as, perfusion and oxygenation, is of great importance for the characterization of pathologies e.g., tumors, which may be helpful to better predict treatment response and potential outcome. To better understand the influence of physiological parameters on the investigated oxygenation and perfusion sensitive MRI ...
Dawson J A JA Newborn Research Centre, The Royal Women's Hospital, , Melbourne, Victoria, - - 2014
Administration of oxygen in the delivery room is informed by oxygen saturation (SpO2). An oxygen saturation range of 60%-70% is the threshold for administering oxygen in the first minutes after birth. The accuracy of newer generation oximeters to measure SpO2 has not been compared against the 'gold standard', direct arterial ...
Nunes Liane Brescovici LB Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo, Emergency Department, Intensive Care Unit, São PauloSP, Brazil, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Emergency Department, Intensive Care Unit, São Paulo/SP, - - 2014
Veno-venous extracorporeal oxygenation for respiratory support has emerged as a rescue alternative for patients with hypoxemia. However, in some patients with more severe lung injury, extracorporeal support fails to restore arterial oxygenation. Based on four clinical vignettes, the aims of this article were to describe the pathophysiology of this concerning ...
Kolettas Alexander A 1 Anaesthesiology Department, "Saint Luke" Private Clinic, Thessaloniki, Panorama, Greece ; 2 Anaesthesiology Department, 3 Cardiology Department, "AHEPA" University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 4 Pulmonary Department, "G. Papanikolaou" General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece ; 5 Cardiothoracic Surgery Department, "Saint Luke" Private Clinic, Thessaloniki, Panorama, Greece ; 6 Surgery Department (NHS), University General Hospital of Alexandroupolis, Democritus University of Thrace, Alexandroupolis, Greece ; 7 Internal Medicine Department, "Theageneio" Cancer Hospital, Thessaloniki, Greece ; 8 Internal Medicine Department, Regional Hospital of Samos, Samos, Greece ; 9 Onocology Department, 10 Cardiology Department, "Saint Luke" Private Clinic, Thessaloniki, Panorama, - - 2014
Apnoeic oxygenation is an alternative technique of oxygenation which is recommended in the consecutive oxygen administration with varying flows (2-10 lt/min) through a catheter which is positioned over the keel of the trachea. Apnoeic oxygenation maintains for a significant period of time the oxygenation of blood in breathless conditions. This ...
Yessayan Lenar - - 2014
Optical hemoglobin and oxygen saturation sensor (OHOS) monitor when used in combination with other hemodynamic tools may be useful for continuous hemodynamic monitoring during ultrafiltration. The stand-alone OHOS monitor can easily be deployed pre-dialyzer into the extracorporeal circuit of continuous renal replacement therapy (CRRT) systems. To maximize the accuracy of ...
Vasicek Ondrej O Institute of Biophysics, Academy of Sciences of the Czech Republic, v.v.i., Kralovopolska 135, 612 65, Brno, Czech - - 2014
The diverse physiological functions of histamine are mediated through distinct histamine receptors. In this study we investigated the role of H2R and H4R in the effects of histamine on the production of reactive oxygen species by phagocytes in whole blood. Changes in reactive oxygen species (ROS) production by whole blood ...
Saller Elisabeth E Institute for Medical & Molecular Diagnostics Ltd. , Zürich , Switzerland - - 2014
Abstract In two unrelated families, several newborns developed cyanosis within the first days of life. For all of them, consecutive arterial blood gas analyses showed a right shift of the saturation curve, suggesting the presence of a hemoglobin (Hb) variant. A new (G)γ-globin variant was detected, namely (G)γ105(G7)Leu → His; HBG2: c.317T > A, ...
Tajima Yosuke Y Biophysics Program, Molecular Imaging Center, National Institute of Radiological Sciences, Chiba, Japan; Department of Neurological Surgery, Chiba University Graduate School of Medicine, Chiba, - - 2014
Cerebral hemodynamic response to acute hyperoxia was investigated in awake mice. Using laser-Doppler flowmetry (LDF), baseline cerebral blood flow (CBF) and the cerebrovascular responses to whisker stimulation were measured in awake mice during normoxia and hyperoxia. Using two-photon laser scanning microscopy (TPLSM), the changes in cortical microvasculature were measured during ...
Bur A Filip - - 2014
Traumatic hemorrhagic shock resulting in tissue hypoxia is a significant cause of morbidity and mortality in polytraumatized patients. Early identification of tissue hypoxia is possible with microdialysis. The aim of this study was to determine the correlation between a marker of tissue hypoxia (L/P; lactate to pyruvate ratio) and selected ...
Busch David R DR Division of Neurology, Children's Hospital of Philadelphia, Department of Physics and Astronomy, University of Pennsylvania, Philadelphia, PA, 19104. Electronic address: - - 2014
This study measures hemodynamic properties such as blood flow and hemoglobin concentration and oxygenation in the healthy human breast under a wide range of compressive loads. Because many breast-imaging technologies derive contrast from the deformed breast, these load-dependent vascular responses affect contrast agent-enhanced and hemoglobin-based breast imaging. Diffuse optical and ...
Lynch Jennifer M JM University of Pennsylvania, Department of Physics and Astronomy, 209 South 33rd St, Philadelphia, PA 19104. Electronic address: - - 2014
Cerebral oxygen extraction, defined as the difference between arterial and venous oxygen saturations (SaO2 and SvO2), is a critical parameter for managing intensive care patients at risk for neurological collapse. Although quantification of SaO2 is easily performed with pulse oximetry or moderately invasive arterial blood draws in peripheral vessels, cerebral ...
Wehrli Felix W FW Laboratory for Structural Nuclear Magnetic Resonance Imaging, Department of Radiology, Perelman School of Medicine, University of Pennsylvania Medical Center, 1 Founders, 3400 Spruce St, Philadelphia, PA 19104. Electronic address: - - 2014
This brief review of magnetic resonance susceptometry summarizes the methods conceived in the authors' laboratory during the past several years. This article shows how venous oxygen saturation is quantified in large draining veins by field mapping and how this information, in concert with simultaneous measurement of cerebral blood flow, yields ...
Devaraj Divya D Intern Student (CRRI), Department of Public Health Dentistry, Saveetha Dental College , India - - 2014
Hyperbaric oxygen therapy is a rapidly developing treatment modality in various fields of dentistry. It is the administration of 100% oxygen to the patient for a specified time period, to increase the oxygen tension in the tissues and also its dissolution in the blood. This review aims to briefly discuss ...
Malkarnekar Santoshi Balkrishna SB Department of Medicine, Sri Devaraj Urs Medical College, Tamaka, Kolar, Karnataka, - - 2014
Two young women, were reffered to our hospital on two different occasions with history of breathlessness and mental confusion, following consumption of two different bio-organic plant nutrient compounds with a suicidal intent. On examination, they had cyanotic mucous membranes, and their blood samples showed the classic 'dark chocolate brown' appearance. ...
Rosenthal Guy G Department of Neurosurgery, Hadassah-Hebrew University Medical Center, Jerusalem, Israel; - - 2014
Object Development of a noninvasive monitor to assess cerebral oxygenation has long been a goal in neurocritical care. The authors evaluated the feasibility and utility of a noninvasive cerebral oxygenation monitor, the CerOx 3110, which uses near-infrared spectroscopy and ultrasound to measure regional cerebral tissue oxygenation in patients with severe ...
Arikan Fuat F Departments of *Neurosurgery †Neurosurgery and Neurotraumatology Research Unit (UNINN) ‡Anesthesiology, Vall d'Hebron University Hospital, Vall d'Hebron Research Institute, Universitat Autonoma de Barcelona, Barcelona, - - 2014
In normal perfusion pressure breakthrough (NPPB) it is assumed that following arteriovenous malformation (AVM) resection, vasoparalysis persists in the margins of the lesion and that a sudden increase in cerebral blood flow (CBF) after AVM exclusion leads to brain swelling and postsurgical complications. However, the pathophysiology NPPB remains controversial.The aim ...
Merdin Alparslan A Department of Internal Medicine, Akdeniz University Hospital , Antalya, - - 2014
Red blood cells carry oxygen in the body and Glucose-6-Phosphate Dehydrogenase protects these cells from oxidative chemicals. If there is a lack of Glucose-6-Phosphate Dehydrogenase, red blood cells can go acute hemolysis. Convulsion is a rare presentation for acute hemolysis due to Glucose-6-Phosphate Dehydrogenase deficiency. Herein, we report a case ...
Golub Aleksander S AS Virginia Commonwealth University, United - - 2014
The prevailing metabolic theory of local blood flow regulation suggests the dilation of arterioles in response to tissue hypoxia via the emission of multiple metabolic vasodilators by parenchymal cells. We have proposed a mechanism of regulation, built from well-known components, which assumes that arterioles are normally dilated in metabolically active ...
Schlanstein Peter C PC * Both authors contributed equally to this - - 2014
Oxygenators have been used in neonatal extracorporeal membrane oxygenation (ECMO) since the 1970s. The need to develop a more effective oxygenator for this patient cohort exists due to their size and blood volume limitations. This study sought to validate the next design iteration of a novel oxygenator for neonatal ECMO ...
Oellermann Michael M Alfred Wegener Institute for Polar and Marine Research, - - 2014
Oxygen equilibrium curves have been widely used to understand oxygen transport in numerous organisms. A major challenge has been to monitor oxygen binding characteristics and concomitant pH changes as they occur in vivo, in limited sample volumes. Here we report a technique allowing highly resolved and simultaneous monitoring of pH ...
Kisielewicz C C Queen Mother Hospital for Animals, Royal Veterinary College, Hatfield, Hertfordshire, - - 2014
There are no standardized guidelines for determining the likelihood that euvolemic anemic dogs will benefit from transfusion of packed red blood cells (pRBC). To report clinical and laboratory variables of dogs receiving pRBC transfusion, which could guide transfusion of other anemic dogs. Twenty-four client-owned anemic dogs receiving pRBC transfusion. Prospective ...
Carhart-Harris Robin L RL Centre for Neuropsychopharmacology (RLC-H, DE, LTJW, LR, SB, RT, AS, TMW, MB, DJN) and C3NL (RL). Electronic address: - - 2014
The compound 3,4-methylenedioxymethamphetamine (MDMA) is a potent monoamine releaser that produces an acute euphoria in most individuals. In a double-blind, placebo-controlled, balanced-order study, MDMA was orally administered to 25 physically and mentally healthy individuals. Arterial spin labeling and seed-based resting state functional connectivity (RSFC) were used to produce spatial maps ...
Liu Peiying P Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, - - 2014
The cerebral metabolic rate of oxygen (CMRO2 ) is the rate of oxygen consumption by the brain, and is thought to be a direct index of energy homeostasis and brain health. However, in vivo measurement of CMRO2 is challenging, in particular for the neonatal population, in whom conventional radiotracer methods ...
Courtens Emilie N P EN Laboratory of Microbial Ecology and Technology (LabMET), Ghent University, Coupure Links 653, 9000 Gent, - - 2014
With oxygen supply playing a crucial role in an oxygen-limited autotrophic nitrification/denitrification (OLAND) rotating biological contactor (RBC), its controlling factors were investigated in this study. Disc rotation speeds (1.8 and 3.6rpm) showed no influence on the process performance of a lab-scale RBC, although abiotic experiments showed a significant effect on ...
Pavlisko Noah D ND Department of Small Animal Clinical Science, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Polytechnic Institute and State University, Blacksburg, VA - - 2014
Objective-To evaluate tissue oxygen saturation (Sto2) by use of near-infrared spectroscopy in experimental acute hemorrhagic shock and resuscitation in dogs. Animals-14 healthy adult purpose-bred Beagles. Procedures-Dogs were anesthetized with isoflurane via facemask, anesthesia was maintained with propofol and rocuronium bromide, and dogs were mechanically ventilated to maintain normocapnia. Dogs were ...
Pérez-Merino Eva M EM Department of Animal Medicine and Surgery, Veterinary Faculty, University of Extremadura, Avda. Universidad s/n, 10003 Cáceres, - - 2014
Our objectives were to standarize the procedure needed to reproduce a similar surgical scene which a pediatric surgeon would face on repairing a Bochdalek hernia in newborns and to define the optimal time period for hernia development that achieve a realistic surgical scenario with minimimal animal suffering. Twenty New Zealand ...
Hu Jichao J 0000-0002-7584-369X Harbin Institute of Technology, Xidazhi Street No. 92, Harbin, Heilongjiang 150001, - - 2014
A Rocket Based Combined Cycle combustor model is tested at a ground direct connected rig to investigate the flame holding characteristics with a small rocket exhaust using liquid kerosene. The total temperature and the Mach number of the vitiated air flow, at exit of the nozzle are 1505 K and 2.6, ...
Aynur Sebnem Koyunluoglu - - 2014
The objective of this research was to understand the influence of oxygenation at two different oxygen flow rates (0.105 and 0.210 L/L/h) on autothermal thermophilic aerobic digestion (ATAD), and on the overall performance of Dual Digestion (DD). Profile experiments on an ATAD reactor showed that a significant portion of volatile ...
Bain Anthony R AR Centre for Heart Lung and Vascular Health, University of British Columbia Okanagan, BC, - - 2014
Hyperthermia is associated with marked reductions in cerebral blood flow (CBF). Increased distribution of cardiac output to the periphery, increases in alveolar ventilation and resultant hypocapnia each contribute to the fall in CBF during passive hyperthermia; however, their relative contribution remains a point of contention, and probably depends on the ...
Nasseri Nassim N Biomedical Optics Research Laboratory, Division of Neonatology, University Hospital of Zürich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland, - - 2014
We recently introduced a novel textile-based NIRS sensor (TexNIRS). Here, we evaluate TexNIRS in ten subjects (16 legs, age 28.5 ± 2.32 years, adipose tissue thickness (ATT) 4.17 ± 1.71 mm). Three venous occlusions at 50 mmHg were performed on their calf muscle. After 3 min of occlusion, oxy/deoxy hemoglobin ...
Harrison David K DK Microvascular Measurements, 39030, St Lorenzen, Italy, - - 2014
Heterogeneity is a feature of both normal oxygen supply to tissue and of a supply that is disturbed due to a wide range of different pathologies. Here, the physiological importance of heterogeneity of tissue oxygenation is revisited. The anatomical and functional basis for heterogeneity of blood flow, local and regional ...
Takemura Naohiro N Laboratory of Integrative Biomedical Engineering, Department of Electrical and Electronics Engineering, College of Engineering, Nihon University, Koriyama, Fukushima, 963-8642, Japan, - - 2014
Patients with cerebral ischemia or brain tumor have been reported to exhibit an increase of deoxygenated hemoglobin (deoxy-Hb) together with an increase of oxygenated hemoglobin (oxy-Hb). However, the physiological mechanisms underlying this hemodynamic response pattern are unclear. In this study, we performed a simulation using the balloon model (Buxton et ...
Pape A A Department of Anesthesia, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt/Main, - - 2013
Background: During acellular replacement of an acute blood loss, hyperoxic ventilation (HV) increases the amount of O2 physically dissolved in the plasma and thereby improves O2 supply to the tissues. While this effect could be demonstrated for HV with inspiratory O2 fraction (FiO2) 0.6, it was unclear whether HV with ...
Tiba Mohamad H MH From the Department of Emergency Medicine (M.H.T., G.T.D., K.R.W.) and the Michigan Center for Integrative Research in Critical Care (M.H.T., G.T.D., K.R.W.), University of Michigan, Ann Arbor, Michigan; Departments of Emergency Medicine (R.W.B.) and Chemistry (J.T.), the Virginia Commonwealth University Reanimation Engineering Science Center (R.W.B., J.T.), Virginia Commonwealth University, Richmond, Virginia; Damage Control Resuscitation (I.T.F.), US Army Institute for Surgical Research, Fort Sam Houston, San Antonio, Texas; Pendar Medical (P.R., D.V.), Cambridge, - - 2013
The ability to monitor the patient of hemorrhage noninvasively remains a challenge. We examined the ability of resonance Raman spectroscopy to monitor tissue hemoglobin oxygenation (RRS-StO2) during hemorrhage and compared its performance with conventional invasive mixed venous (SmvO2) and central venous (ScvO2) hemoglobin oxygen saturation as well as with near-infrared ...
Fantini Sergio S Department of Biomedical Engineering, Tufts University, 4 Colby Street, Medford, MA 02155, - - 2014
A recent dynamic model relates the functional near-infrared spectroscopy (fNIRS) measurements to hemodynamic and metabolic parameters. This note reports modified expressions of the new model in terms of cerebral blood volume (CBV), blood flow (CBF) and metabolic rate of oxygen (CMRO2). On the basis of these modified expressions, the new ...
Jain Varsha - - 2013
Neonatal congenital heart disease (CHD) is associated with altered cerebral hemodynamics and increased risk of brain injury. Two novel noninvasive techniques, magnetic resonance imaging (MRI) and diffuse optical and correlation spectroscopies (diffuse optical spectroscopy (DOS), diffuse correlation spectroscopy (DCS)), were employed to quantify cerebral blood flow (CBF) and oxygen metabolism ...
Hansen Jan Hinnerk - - 2013
Low cerebral tissue oxygenation saturations have been observed by near-infrared spectroscopy (NIRS) after the Norwood procedure. Altered cerebral vascular resistance and pharmacological afterload reduction redirecting blood flow away from the cerebral circulation are possible mechanisms. Two different afterload reduction strategies were evaluated in patients with hypoplastic left heart syndrome or ...
Wachsmuth Nadine N Department of Sports Medicine/Sports Physiology, University of Bayreuth, , Bayreuth, - - 2013
The optimal strategy for soccer teams playing at altitude is not known, that is, 'fly-in, fly-out' versus short-term acclimatisation. Here, we document changes in blood gas and vascular volumes of sea-level (Australian, n=20) and altitude (Bolivian, n=19) native soccer players at 3600 m. Haemoglobin-oxygen saturation (Hb-sO₂), arterial oxygen content (CaO₂), ...
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