Search Results
Results 351 - 400 of 1554
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Lee Chih-Hung - - 2006
OBJECTIVE: The purpose of this study is to evaluate the effect of linear polarized light irradiation near the stellate ganglion area on cutaneous blood flow in fingers of patients with progressive systemic sclerosis. BACKGROUND DATA: Sympathetic overactivity is known to be present in patients with progressive systemic sclerosis. Recently introduced ...
Ohtani Maki - - 2007
We report an autopsy case of a man who suffered accidental chemical burns following exposure to 60% hydrofluoric acid. The extent of the burns covered about 30% of his body surface, and cardiopulmonary arrest occurred about 30min after the exposure. At autopsy, the skin of the affected area showed greenish ...
Gooding Kim M - - 2006
BACKGROUND: Maximum skin hyperaemia (MH) induced by heating skin to > or = 42 degrees C is impaired in individuals at risk of diabetes and cardiovascular disease. Interpretation of these findings is hampered by the lack of clarity of the mechanisms involved in the attainment of MH. METHODS: MH was ...
Yang Shih-Hung - - 2006
BACKGROUND: Palmar hyperhidrosis is effectively treated by thoracic sympathectomy. Previous reports revealed that palmar skin temperature and perfusion increased on focal palmar regions after treatment. This study aimed to investigate the blood flow change over the whole palmar surface after the procedure. METHODS: Thirty patients with severe palmar hyperhidrosis were ...
Wright Thomas C - - 2006
Palmar finger skin reacts to extension under mechanical load -- blanching over proximal (intercrease skin, ICS) and middle phalanges, while blushing in crease skin (CS), which we have called the Blanch-Blush Reaction (BBR). The idea that the BBR is a result of surface capillary blood flow changes that relate to ...
Bernard Francis - - 2006
Use of arginine vasopressin in the management of refractory vasodilatory shock has been associated with development of ischaemic skin lesions. Because of the increasing popularity of arginine vasopressin, it is important to evaluate its effects on microcirculatory blood flow. Such studies are crucial if we are to appreciate the microcirculatory ...
Jacobi Ute - - 2006
The topical application of drugs, such as nicotinates, affects cutaneous blood flow. Such a biological response, which is dependent on the drug and the individual, can be measured noninvasively using laser Doppler flowmetry. We illustrate the kinetics of vasodilation caused by topically applied benzyl nicotinate using a new frequency-selective laser ...
Martanto Wijaya - - 2006
PURPOSE: The aim of the study is to determine the effect of experimental parameters on microinfusion through hollow microneedles into skin to optimize drug delivery protocols and identify rate-limiting barriers to flow. METHODS: Glass microneedles were inserted to a depth of 720-1080 microm into human cadaver skin to microinfuse sulforhodamine ...
Torres M J - - 2006
Allergic drug reactions can be classified as immediate, accelerated or delayed. This classification usually correlates with the mechanism involved: immediate reactions are IgE mediated and delayed reactions are T cell dependent. We analyzed lymphocyte involvement in patients with these reactions by determining cell subpopulations, activation state and skin homing receptor ...
Hagermann Axel - - 2005
The year 2005 marks the 35th anniversary of the Apollo 13 mission, probably the most successful failure in the history of manned spaceflight. Naturally, Apollo 13's scientific payload is far less known than the spectacular accident and subsequent rescue of its crew. Among other instruments, it carried the first instrument ...
Negro Juan José - - 2006
So far overlooked as a pigment involved in visual communication, the haemoglobin contained in the blood of all birds is responsible for the red flushing colours in bare skin areas of some species. Our aim has been twofold: (1) to study sub-epidermical adaptations for blood circulation in two flushing species: ...
Klingel Reinhard - - 2005
Rheopheresis is a specifically designed application of double filtration plasmapheresis, for extracorporeal treatment of microcirculatory disorders. Safety and efficacy of Rheopheresis for wound healing and skin oxygenation were investigated in patients with critical limb ischemia. Twelve patients of Fontaine stage III-IV were treated with a series of 10 Rheopheresis sessions ...
Allen John - - 2006
Vascular and clinical assessments of arterio-venous fistula (AVF) function and access are important in patients undergoing or preparing to undergo renal dialysis. Objective assessment techniques include colour duplex ultrasound and more recently medical infrared thermography. Ideally, these should help assess problems relating to fistula failure or to vascular steal from ...
Yosipovitch Gil - - 2005
The aim of this study was to assess the effect of thermal stimuli or distal scratching on skin blood flow and histamine-induced itch in healthy volunteers. Twenty-one healthy volunteers participated in the study. Baseline measurements of skin blood flow were obtained on the flexor aspect of the forearm. These measurements ...
Nicotra Alessia - - 2005
OBJECTIVE: Spinal cord injury (SCI) results in disruption of descending tonic activation of sympathetic circuits in the spinal cord. The authors determined whether different stimuli that increase sympathetic activity induced cutaneous vasoconstriction (skin vasomotor reflex, SkVR) above and below the level of lesion in subjects with clinically complete SCI. METHODS: ...
Cui Jian - - 2006
Skin sympathetic nerve activity (SSNA) exhibits low- and high-frequency spectral components in normothermic subjects. However, spectral characteristics of SSNA in heat-stressed subjects are unknown. Because the main components of the integrated SSNA during heat stress (sudomotor/vasodilator activities) are different from those during normothermia and cooling (vasoconstrictor activity), we hypothesize that ...
Wright C I - - 2006
Vessels in the skin are arranged into superficial and deep horizontal plexuses and they are involved in thermoregulation, oxygen and nutritional support. The skin has a large number of functions and broad appeal spanning basic mechanistic and clinical research. Indeed, the skin can be used as a marker of normal ...
Wick Diane E - - 2006
Epidemiological evidence suggests decreased heat tolerance in patients with Type 2 diabetes mellitus (T2DM), but it is not known whether the mechanisms involved in thermoregulatory control of skin blood flow are altered in these patients. We tested the hypothesis that individuals with T2DM have a delayed internal temperature threshold for ...
Narbutt Joanna - - 2005
Background/purpose: Dendritic cells (DC) play a major role in the afferent immune response. They are found as a minor cell population in the blood as three main subtypes that can be distinguished phenotypically: plasmacytoid DC (PDC), and myeloid DC1 and 2 (MDC1 and 2). The aim of the study was ...
Mordon Serge - - 2005
BACKGROUND AND OBJECTIVES: Laser irradiation induces blood coagulation by heating of blood components. It is a complex phenomenon which encompasses a variety of processes, such as cell shape modification, cell membrane rupture, protein denaturation, aggregation, and finally blood gelation. An in vitro study was performed to investigate heating temperatures leading ...
Jay Ollie - - 2006
To assess the presence and magnitude of the effect of skin blood flow on finger skin cooling on contact with cold objects against the background of circulatory disorder risks in occupational exposures, this study investigates the effect of zero vs. close-to-maximal hand blood flow on short-term (< or =180 s) ...
Yamazaki Fumio - - 2006
Local cooling of nonglabrous skin without functional sympathetic nerves causes an initial vasodilation followed by vasoconstriction. To further characterize these responses to local cooling, we examined the importance of the rate of local cooling and the effect of nitric oxide synthase (NOS) inhibition in intact skin and in skin with ...
Lima Alexandre - - 2005
Early hemodynamic assessment of global parameters in critically ill patients fails to provide adequate information on tissue perfusion. It requires invasive monitoring and may represent a late intervention initiated mainly in the intensive care unit. Noninvasive monitoring of peripheral perfusion can be a complementary approach that allows very early application ...
Davis Scott L - - 2006
Near-infrared (NIR) spectroscopy is a noninvasive optical technique that is increasingly used to assess muscle oxygenation during exercise with the assumption that the contribution of skin blood flow to the NIR signal is minor or nonexistent. We tested this assumption in humans by monitoring forearm tissue oxygenation during selective cutaneous ...
Alekseev S I - - 2005
We investigated the influence of blood perfusion on local heating of the forearm and middle finger skin following 42.25 GHz exposure with an open ended waveguide (WG) and with a YAV mm wave therapeutic device. Both sources had bell-shaped distributions of the incident power density (IPD) with peak intensities of ...
Fujita Takeo - - 2005
OBJECTIVE: Postoperative compensatory sweating (PCS) is an important problem impacting on quality of life for patients after endoscopic thoracic sympathectomy (ETS). The present study investigated whether intraoperative palmar temperature and blood flow are useful for assessing PCS after ETS. METHODS: Retrospectively, results were evaluated for ETS in 27 consecutive patients ...
Jan Yih-Kuen - - 2005
The study of skin blood flow responses is confounded by temporal variability in blood flow measurements. Spectral analysis has been shown useful in isolating the effects of distinct control mechanisms on various stimuli in the microcirculatory system. However, the sensitivity of spectral analysis to temporal blood blow variability has not ...
Nishidate Izumi - - 2005
A simple method is proposed for visualizing the depth distribution of a local blood region in skin tissue by using diffuse reflectance images at two isosbestic wavelengths of hemoglobin, 420 and 585 nm. Monte Carlo simulation of light transport specifies a relation between optical densities and the depth of the ...
Youn Choon Shik - - 2005
BACKGROUND/PURPOSE: As most biochemical systems are affected by temperature, thermal changes before or after ultraviolet (UV) irradiation could influence skin vascular blood flow changes and inflammatory responses. In this study, our aim was to investigate the influence of thermal changes on UV-induced acute skin reactions, namely, erythema and pigmentation. METHODS: ...
Buono Michael J - - 2005
Skin blood flow affects NIRS. Leg skin blood flow (SkBF) was increased and decreased following local heating and intradermal epinephrine injection. Epinephrine decreased muscle saturation (StO(2)), and heating the leg increased StO(2). The results suggest that changes in SkBF can significantly affect resting StO(2) as measured by near-infrared tissue spectroscopy.
Dekker Teun - - 2005
Female mosquitoes are noted for their ability to use odours to locate a host for a blood meal. Two sensory organs contribute to their sense of smell: the maxillary palps, which measure the level of CO2, and the antennae, which detect other host-released odours. To establish the relative importance and ...
Tokumoto Seiji - - 2005
The effect of electroporation on the iontophoresis-produced electroosmosis across the skin was evaluated by measuring the permeability of hairless mouse skin, to mannitol, a non-electrolyte, in vitro. Immediately after electroporation by squared pulses (10 times/s) at 100, 150 or 200 V for 1 ms, anodal iontophoretic permeations were determined at ...
Meyer M F - - 2005
Early detection of synovitis in rheumatoid arthritis (RA) and distinction from osteoarthritis (OA) are important to establish the most appropriate treatment. Increased perfusion over affected joints observed by laser Doppler perfusion imaging was supposed to arise from the underlying joint, because it was detected only by a near-infrared laser and ...
Miyai Nobuyuki - - 2005
Measurements of changes in finger skin blood flow with laser Doppler perfusion imaging (LDPI) in response to cold provocation test (10 degrees C, 10 min) were performed in 12 men suffering from vibration induced white finger (VWF) and 13 exposed controls. The mean perfusion values in both groups reduced markedly ...
Dekker Pim - - 2005
In a study of biomarkers of ultraviolet-A1 radiation (UV-A1)-induced skin damage, living skin equivalent cultures (LSE) were treated with the antioxidants hesperetin and quercetin-3-glucoside and irradiated with 25 or 50 J/cm2 UV-A1. Changes in the following biomarkers were measured; Interleukin 1-alpha (IL-1alpha), Heme Oxygenase-1 (HO-1), TdT-mediated dUTP nick end labeling ...
Klaessens John H G M - - 2005
The influence of skin on the bias and reproducibility of regional cerebral oxygenation measurements is investigated using cw near-infrared spectroscopy (NIRS). Receiving optodes are placed over the left and right hemispheres of a piglet (C3, C4 EEG placement code) and one transmitting optode centrally (Cz position). Optical densities (OD) are ...
Kaufman J W - - 2006
Oral heat and water vapor transport may play a significant role in maintaining airway health. This study intended to develop a technique for measuring heat and mass transfer coefficients in the human oral cavity as a function of flow rate. A multi-thermocouple probe was developed which simultaneously measures dry and ...
Brienza David M - - 2005
OBJECTIVE: To differentiate blood flow control mechanisms associated with indentation from those associated with heating and to discern heat-induced and pressure-induced changes by comparing the effect of externally applied stress on skin blood flow (SBF) to the response to externally applied heat. DESIGN: Repeated-measures design. SETTING: A university research laboratory. ...
Murray A K - - 2005
BACKGROUND: Increased blood flow occurs in plaques of psoriasis, and an increase in blood flow has been shown to occur in uninvolved skin adjacent to the active edge. OBJECTIVES: In order to gain more insight into the pathophysiology of the active edges of plaques of psoriasis, we investigated different components ...
Clark T D - - 2005
To maximize the period where body temperature (Tb) exceeds ambient temperature (Ta), many reptiles have been reported to regulate heart rate (fH) and peripheral blood flow so that the rate of heat gain in a warming environment occurs more rapidly than the rate of heat loss in a cooling environment. ...
von Bülow Silvester - - 2005
Thrombomodulin (CD 141) is an endothelial surface transmembrane glycoprotein. It is involved in the activation of protein C in the inactivation of thrombin. In severe sepsis CD 141 is shed from the endothelial surface. This leads to disseminated intravascular coagulation (DIC), disturbed organ functions and multi organ failure (MOF). In ...
de Moraes Marcos F P G - - 2005
In light of the relationship of lungfish to the origin of tetrapods, information on the respiratory biology of lungfish can give insight into the functional morphological and physiological prerequisites for the conquest of land by the first tetrapods. Stereological methods were employed in order to determine the respiratory surface area ...
Petrofsky Jerrold - - 2005
BACKGROUND: Both endothelial cell function and autonomic function are influenced by age. However, the interrelationships between the 2 have not been carefully examined. MATERIAL/METHODS: Thirty nondiabetic control subjects (C) and 25 subjects with type 2 diabetes (D) participated. Endothelial cell function was assessed by 4 minutes of occlusion of the ...
Opazo Saez Anabelle M - - 2005
The purpose of this study was to evaluate the repeatability of forearm skin blood flow responses to intradermal injections of acetylcholine (ACh) and endothelin-1 (ET-1) using a double injection technique (DIT) and a laser Doppler imager (LDI) scanner in the human skin microcirculation. We used a laser Doppler imager (Moor ...
Bukiej Aleksandra - - 2005
We report on a 45-year-old female who developed eosinophilic fasciitis, characterized by scleroderma-like skin indurations, predominantly on the extremities and chest, with joint contractures and intermittent blood eosinophilia. Histologic examination revealed fibrosis of muscle fascia and eosinophilic infiltration. High-dose systemic corticosteroid therapy was ineffective, but cyclosporine treatment led to remission.
van der Sande Frank M - - 2005
The cause of the increase in core temperature (CT) during hemodialysis (HD) is still under debate. It has been suggested that peripheral vasoconstriction as a result of hypovolemia, leading to a reduced dissipation of heat from the skin, is the main cause of this increase in CT. If so, then ...
Kimel Sol - - 2005
BACKGROUND AND OBJECTIVES: Hypervascular skin lesions (HVSL) are treated with medical lasers characterized by a variety of parameters such as wavelength lambda, pulse duration t(p), and radiant exposure E that can be adjusted for different pathology and blood vessel size. Treatment parameters have been optimized assuming constant optical properties of ...
Bihari Imre - - 2005
BACKGROUND: The accepted pathophysiology of telangiectasias is reflux from superficial or deep veins. There are physical signs and scientific findings that do not fit this theory but support the possibility of arteriovenous (AV) shunt origin. OBJECTIVE: If there is a higher flow in spider veins than in the surrounding skin, ...
Wilson Thad E - - 2005
The purpose of this project was to test the hypothesis that, independent of neural control, glabrous and nonglabrous cutaneous vasculature is capable of autoregulating blood flow. In 10 subjects, spectral and transfer function analyses of arterial pressure and skin blood flow (laser-Doppler flowmetry) from glabrous (palm) and nonglabrous (forearm) regions ...
Wang Wen - - 2005
OBJECTIVE: Papillary loops in dermal papillae are believed to facilitate oxygen delivery to the germinal layer in the epidermis. The study aims to simulate the distribution of the oxygen partial pressure, pO2, in superficial layers of skin and to quantify oxygen supply from different sources. METHODS: A theoretical model that ...
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