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Gibb Herman - - 2011
This study evaluates biomarkers of mercury exposure among residents of Horlivka, a city in eastern Ukraine located in an area with geologic and industrial sources of environmental mercury, and residents of Artemivsk, a nearby comparison city outside the mercury-enriched area. Samples of urine, blood, hair, and nails were collected from ...
Lim K J - - 2012
To determine the frequency of intratumoural flow and peritumoural hepatofugal portal flow using colour Doppler sonography (CDS) on hepatic haemangiomas with arterioportal shunt (APS), and to investigate possible factors that may affect the capability of CDS to depict such findings. The study included 45 patients (35 men, 10 women; mean ...
Ruangwises Suthep - - 2011
Concentrations of total and inorganic arsenic were determined in 120 samples of eight marine animals collected from the Gulf of Thailand between March and May 2008. Two species with the highest annual catch from each of four marine animal groups were analyzed: fish (Indo-Pacific mackerel and goldstripe sardine), bivalves (green ...
Sun Zhenghui - - 2012
The aim of this study was to determine the effect of vagus nerve stimulation (VNS) on infarct size after transient and after permanent focal cerebral ischemia in rats and to test the hypothesis that VNS-induced neuroprotection is due to changes in cerebral blood flow. Ischemia was produced by either temporary ...
Tekin Deniz - - 2011
Metallothionein affects the metabolism, transport and storage of micronutrients such as zinc, copper and iron, and the detoxification of heavy metals, especially cadmium. Cd is a common, highly toxic environmental pollutant that accumulates in human placenta, elevated concentrations of which are associated with impaired zinc transfer to the fetus. This ...
Horii Yuko - - 2011
We observed that olfactory stimulation with scent of grapefruit oil elevated the activities of sympathetic nerves, and increased the plasma glycerol concentration and blood pressure. In contrast, olfactory stimulation with scent of lavender oil had opposite effects in rats. These suggest that changes in autonomic activities cause physiological functions via ...
Blaise S - - 2011
The treatment of scleroderma-related digital ulcers is still a therapeutic challenge. The most effective drugs are prostacyclin analogues. However, their usage is limited to an intravenous route of administration and by their frequent side effects. The objective of this study was to test whether treprostinil, iloprost and epoprostenol can induce ...
Wu Chin-Ching - - 2011
Prostate cancer associated with cadmium exposure may indicate a link between prostate specific antigen (PSA) and levels of blood cadmium (BCd) and urinary cadmium (UCd). Thus, these associations were investigated. We recruited 295 men, 50years of age and above from a health check-up program at a health center as subjects ...
Ramon R - - 2011
BACKGROUND: Mercury is a ubiquitous heavy metal that may negatively affect human health. It is desirable to investigate mercury exposure in vulnerable populations. OBJECTIVE: To determine the concentrations of total mercury (T-Hg) in cord blood and to evaluate the role of maternal fish consumption in a Spanish mother and child ...
Gil Fernando - - 2011
Heavy metal contamination from occupational origin is a cause for concern because of its potential accumulation in the environment and in living organisms leading to long term toxic effects. This study was aimed to assess Cd, Cr, Mn, Ni and Pb levels in whole blood, urine, axillary hair and saliva ...
Ho G - - 2011
A case of lead exposure resulting from the accidental ingestion of a lead-containing solution is reported. Because of clinical management rapidly performed through chelation therapy by 2,3-dimercaptopropane sulfonate sodium and meso-2,3-dimercaptosuccinic acid, blood lead levels of this 51-year-old patient were moderate (412.9 μg/L) and no clinical symptoms were observed. Numerous ...
Davis Diane - - 2011
To define entry level competencies in flow cytometry for CLS generalists. Flow cytometry practitioners completed an electronic survey. Of 134 respondents, 131 met the desired demographics and were analyzed. Links to the survey were mailed to 3 listservs (Medlab-L, CLSEduc, Purdue Cytometry) and 2 email groups (ASCLS and AMLI). Participants ...
Abadi Uri - - 2011
SUMMARY: BACKGROUND: Red blood cell (RBC) transfusion in hemorrhagic shock is life saving. However, several clinical trials have shown that blood transfusion in the critically ill patient might be associated with adverse outcomes. Furthermore, an association between prolonged blood storage and adverse effects of RBC transfusion has been postulated. The ...
Fricano Meagan M - - 2011
Blood is an ideal tissue for the identification of novel genomic biomarkers for toxicity or efficacy. However, using blood for transcriptomic profiling presents significant technical challenges due to the transcriptomic changes induced by ex vivo handling and the interference of highly abundant globin mRNA. Most whole blood RNA stabilization and ...
Groß T F - - 2011
A hysteresis effect in the pressure/flow rate relationship of nasal breathing has frequently been observed in clinical tests and in lab investigations. Explanations that have been given in the literature are missing a fluid mechanic storage effect coming into play in reciprocating flows. This effect depends primarily on the way ...
Sasaki Masanori - - 2011
Most experimental stroke research is carried out in rodents, but given differences between rodents and human, nonhuman primate (NHP) models may provide a valuable tool to study therapeutic interventions. The authors developed a surgical method for transient occlusion of the M1 branch of middle cerebral artery (MCA) in the African ...
Penteado Fernando Travaglini - - 2011
The aim of this study was to analyze the effect of high-energy extracorporeal shockwave therapy on tendon angiogenesis in the patellar tendons of rabbits. We sought to investigate whether different voltage and number pulses modify the angiogenesis pattern. High-energy extracorporeal shockwave therapy is an option in the treatment of orthopedic ...
Sipos Ferenc F 2nd Department of Internal Medicine, Semmelweis University, Budapest, Hungary. - - 2011
A molecular diagnostic assay using easily accessible peripheral blood would greatly assist in the screening and diagnosis of ulcerative colitis (UC) and Crohn's disease (CD). Transcriptional profiles in blood/biopsy samples from 12 UC (6/12), 9 CD (5/9), 6 non-inflammatory bowel disease (non-IBD) colitis (6/0), and 11 healthy (11/11) patients were ...
Reimann Katrin K Anatomy & Physiology Department, Kansas State University, Manhattan, Kansas, United States of - - 2011
Regulation of cochlear blood flow is critical for hearing due to its exquisite sensitivity to ischemia and oxidative stress. Many forms of hearing loss such as sensorineural hearing loss and presbyacusis may involve or be aggravated by blood flow disorders. Animal experiments and clinical outcomes further suggest that there is ...
Lin Chien-Mu - - 2010
Objectives Cadmium is known to be a significant health hazard, but most information comes from studies of adults. The effects of exposure to cadmium during fetal life on early growth and development remain uncertain. In this study we investigated the placental transport of cadmium and the effects of prenatal cadmium ...
Clark Scott - - 2011
The Evaluation of the US Department of Housing and Urban Development Lead-Based Paint Hazard Control Grant Program studied the effectiveness of the housing intervention performed in reducing the blood lead of children at four post-intervention times (6-months, 1-year, 2-years, and 3-years). A repeat measures analysis showed that blood lead levels ...
Lyon-Roberts Brianna - - 2011
Collecting duct (CD) endothelin-1 (ET-1) is an important autocrine inhibitor of CD Na(+) reabsorption. Salt loading is thought to increase CD ET-1 production; however, definitive evidence of this, as well as understanding of the mechanisms transducing this effect, is lacking. Tubule fluid flow increases in response to Na(+) loading; hence, ...
Aamodt K - - 2010
We report the first measurement of charged particle elliptic flow in Pb-Pb collisions at sqrt[S(NN)] =2.76 TeV with the ALICE detector at the CERN Large Hadron Collider. The measurement is performed in the central pseudorapidity region (|η|<0.8) and transverse momentum range 0.2<p t<5.0 GeV/c. The elliptic flow signal v₂, measured ...
Zhang Yun - - 2011
A convenient and efficient flow method for Ullmann condensations, Sonogashira couplings, and decarboxylation reactions using a commercially available copper tube flow reactor (CTFR) is described. The heated CTFR effects these transformations without added metals (e.g., Pd), ligands, or reagents, and in greater than 90% yield in most cases examined.
Louis Elan D - - 2011
Tremor is a widespread phenomenon in human populations. Environmental factors are likely to play an etiological role. Harmane (1-methyl-9H-pyrido[3,4-β]indole) is a potent tremor-producing β-carboline alkaloid. Lead is another tremor-producing neurotoxicant. The effects of harmane and lead with respect to tremor have been studied in isolation. We tested the hypothesis that ...
Varian-Ramos Claire W - - 2011
It is unclear whether mercury concentration in wildlife tissues changes appreciably after lengthy frozen storage. To test whether such freezer-archived samples are stable, small (~10-50 μL) avian blood samples stored in capped glass capillary tubes were analyzed for total mercury concentration, and then reanalyzed after being frozen for up to 3 years. ...
Wang Zhaoyue - - 2010
We report a typical case of hematidrosis in a Chinese girl who had experienced frequent bleeding episodes for more than 3 years. During hospitalization, spontaneous bleeding from her intact skin was witnessed by our staff on more than 20 occasions. Characteristically, bloody droplets from the intact skin contained all blood ...
Vinodhini Rajamanickam - - 2010
The objective of this study was to investigate the efficacy of Nelumbo nucifera and Aegle marmelos on common carp exposed to sub-lethal concentrations of combined heavy metals (5 ppm) under laboratory conditions. The fish were treated with Nelumbo nucifera (500 mg/kg bwt) and Aegle marmelos (500 mg/kgbwt) for 30 days ...
Bloom Michael S - - 2010
Trace exposures to the toxic metals mercury (Hg), cadmium (Cd) and lead (Pb) may interfere with in vitro fertilization (IVF). The aim of this study is to explore biologically plausible hypotheses concerning associations between metals and embryo quality indicators during IVF. For 24 female patients, a multivariable ordinal logistic regression ...
Simmons G H - - 2011
Hypoxia impairs body temperature regulation and abolishes the decline in skin temperature associated with cold exposure, suggesting that cutaneous vasoconstriction is impaired. Aim:  The purpose of this study was to test the hypothesis that cutaneous vasoconstriction to intradermal tyramine, an index of post-junctional vasoconstrictor responsiveness, is reduced during hypoxia. Methods:  ...
Kelemen Katalin - - 2010
In mycosis fungoides (MF) with blood involvement, T-cell immunophenotypes in skin and blood have not been compared. Our aim was to evaluate T-cell immunophenotypes in skin by immunohistochemical analysis and compare results with flow cytometric (FC) findings in blood. Of 20 patients with MF with blood involvement, the immunophenotype was ...
Välisuo Petri - - 2010
The colour of the skin reflects many physiological and pathological states of an individual. Usually, the skin colour is examined by the bare eye alone. Several scaling systems have been developed to quantify the sensory evaluation of skin colour. In this work, the reflectance of the skin is measured directly ...
Wong Brett J - - 2010
The initial, rapid increase in skin blood flow in response to direct application of heat is thought to be mediated by an axon reflex, which is dependent on intact cutaneous sensory nerves. We tested the hypothesis that inhibition of transient receptor potential vanilloid type 1 (TRPV-1) channels, which are putative ...
Xue Lei - - 2011
We explored the effect of electrochemical therapy for the treatment of high-flow venous malformations in the maxillofacial region in 32 patients. We used a method of anaesthesia that was suitable to the site and size of the lesion, and then inserted platinum needles into the lesion in a sterile environment. ...
Dean Brian - - 2010
The skin of fast-swimming sharks exhibits riblet structures aligned in the direction of flow that are known to reduce skin friction drag in the turbulent-flow regime. Structures have been fabricated for study and application that replicate and improve upon the natural shape of the shark-skin riblets, providing a maximum drag ...
Gryglewska B - - 2010
The aim of our study was to investigate, whether masked hypertension (MH) and sustained hypertension (HT) are associated with alteration of resting skin blood flow and flowmotion. Subjects recruited to the study were assigned to three groups according to the results of blood pressure (BP) measurements. Resting blood flow (RF) ...
Manorama Abinand Anbazhagan - - 2010
Decubitus ulcers (pressure ulcers) are localized areas of tissue breakdown in the skin and the underlying regions. Decubitus ulcers affect approximately 3 million people in the USA every year, including seniors, individuals with diabetes, and those who spend long periods in wheelchairs. Experimental studies demonstrate that static or dynamic normal ...
Lorenzo Santiago - - 2010
The aim of this study was to explore heat acclimation effects on cutaneous vascular responses and sweating to local ACh infusions and local heating. We also sought to examine whether heat acclimation altered maximal skin blood flow. ACh (1, 10, and 100 mM) was infused in 20 highly trained cyclists ...
Sathar Farzana - - 2010
This study examined the skin of two 1- to 2-year-old male giraffes and one adult male, determining skin thickness and histological structure with reference to it functioning as a component of the features required for the maintenance of blood pressure, dermal armor, or thermoregulation. It has been argued that a ...
Rajaram Narasimhan - - 2010
Diffuse reflectance spectroscopy (DRS) uses the steady-state diffuse reflectance measured from the tissue surface to determine absorption and scattering properties of sampled tissue. Many inverse models used to determine absorber properties have assumed a homogeneous distribution of blood. However, blood in tissue is confined to blood vessels that occupy a ...
Petrofsky Jerrold Scott - - 2010
As people age, and especially for older people with diabetes, there is increased susceptibility to burns. However, this is not true for all older people or all people with diabetes. The factors that predict burn susceptibility in specific members of the population with diabetes have not been elucidated. To understand ...
Mistrík Erik - - 2010
Difficulty healing wounds and skin defects is a frequent problem in patients on chronic hemodialysis (HD) because of malnutrition, inflammation, and atherosclerosis (MIA) syndrome. The aim of the present study was to estimate the influence of peripheral blood flow changes during HD on the development of foot defects and its ...
Fredriksson Ingemar - - 2010
Laser Doppler flowmetry (LDF) can be used for assessing the microcirculatory perfusion. However, conventional LDF (cLDF) gives only a relative perfusion estimate for an unknown measurement volume, with no information about the blood flow speed distribution. To overcome these limitations, a model-based analysis method for quantitative LDF (qLDF) is proposed. ...
Gulson Brian - - 2010
Metal oxide nanoparticles are commonly used in personal-care formulations as protective agents against exposure to ultraviolet radiation. Although previous research has concluded that nanoparticles do not penetrate healthy skin, it remains contentious whether this conclusion holds under normal conditions of sunscreen use. Humans (n = 20) were exposed to sunscreens ...
Wingo Jonathan E - - 2010
Sweat rate (SR) is reduced in locally cooled skin, which may result from decreased temperature and/or parallel reductions in skin blood flow. The purpose of this study was to test the hypotheses that decreased skin blood flow and decreased local temperature each independently attenuate sweating. In protocols I and II, ...
Hamilton Kathrin F - - 2010
Heat in blood pumps is generated by losses of the electrical motor and bearings. In the presented study the influence of tempered surfaces on bulk blood and adhesions on these surfaces was examined. Titanium alloy housing dummies were immersed in 25 mL heparinized human blood. The dummies were constantly tempered ...
Brothers R Matthew - - 2010
Skin blood flow responses in the human forearm, assessed by three commonly used technologies-single-point laser-Doppler flowmetry, integrated laser-Doppler flowmetry, and laser-Doppler imaging-were compared in eight subjects during normothermic baseline, acute skin-surface cooling, and whole body heat stress (Δ internal temperature=1.0±0.2 degrees C; P<0.001). In addition, while normothermic and heat stressed, ...
Ye Ying - - 2011
To investigate how temperature influences changes in finger circulation induced by hand-transmitted vibration in healthy subjects, and the variability in individual response to both vibration and temperature. With two room temperatures (20 and 28°C), finger blood flow (FBF) and finger skin temperature (FST) were measured on the left middle fingers ...
Sefton JoEllen M - - 2010
OBJECTIVE: This study's objective was to determine the effect of therapeutic massage on peripheral blood flow utilizing dynamic infrared thermography in a constant temperature/humidity thermal chamber to assess noncontact skin temperature. DESIGN: The design was a repeated-measures crossover experimental design; the independent variable was treatment condition (massage, light touch, control). ...
Kainerstorfer Jana M - - 2010
Multispectral images of skin contain information on the spatial distribution of biological chromophores, such as blood and melanin. From this, parameters such as blood volume and blood oxygenation can be retrieved using reconstruction algorithms. Most such approaches use some form of pixelwise or volumetric reconstruction code. We explore the use ...
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