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Moore Philip W PW Department of Internal Medicine, PinnacleHealth Hospitalists, 111 S. Front St, Harrisburg, PA, 17101; Department of Internal Medicine, PinnacleHealth Toxicology Center, 111 S. Front St, Harrisburg, PA, 17101; Department of Emergency Medicine, Penn State University College of Medicine, 500 University Dr, Hershey, PA, - - 2014
Opioid-related mortality happens, even in healthcare settings. We describe serial postmortem fentanyl blood concentrations in a hospital inpatient who fatally abused transdermal fentanyl. This is a single-patient case report. A 42-year-old man with lymphoma was started on transdermal fentanyl therapy while hospitalized for chronic abdominal pain. The patient was last ...
Spada Eva E Veterinary Transfusion Unit (REV), Department of Health, Animal Science and Food Safety (VESPA), University of Milan, Milan, Italy - - 2014
This prospective study investigated the effect on clinical and haematological variables of the anaesthetic combination of tiletamine and zolezapam in feline blood donors. Blood (10 ml/kg bodyweight to a maximum volume of 60 ml) was collected from the jugular vein of 31 owned healthy cats anaesthetised with 2.5 mg/kg of ...
Chen X X Department of Biomedical Engineering, Key Laboratory of Biomedical Engineering of Ministry of Education of China, Zhejiang University, Hangzhou, Zhejiang, - - 2014
Although pilot studies have reported that exhaled propofol concentrations can reflect intraoperative plasma propofol concentrations in an individual, the blood/exhaled partial pressure ratio RBE varies between patients, and the relevant factors have not yet been clearly addressed. No efficient method has been reported for the quick evaluation of RBE and ...
Mergan Zara Y ZY Department of Anesthesiology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, - - 2014
We present a case of a patient with acute lymphoblastic leukemia (ALL) undergoing an epidural blood patch (EBP) for post-puncture dural headaches despite the risks of spreading cancer cells to the epidural space. A 46-year-old male with a history of adult T-cell ALL presented with persistent positional headache and neutropenic ...
Pape Andreas A From the Department of Anesthesiology, Intensive-Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt am Main, Germany (A.P., C.F.W., M.L., M.S., S.K., O. Horn); Clinic of Anesthesiology, Ludwig Maximilians University Hospital, Munich, Germany (B.Z.); and Clinic of Anesthesiology, Surgical Intensive Care Medicine and Pain Management, Krankenhaus Nordwest, Frankfurt, Germany (O. - - 2014
The initial treatment of an acute blood loss with acellular fluids leads to the dilution of the red cell mass remaining in the vasculature, that is, to acute normovolemic anemia. Whether the compensation and, thus, the tolerance of acute anemia, are affected by sympathetic block induced by thoracic epidural anesthesia ...
Daradka Mousa M Faculty of Veterinary Medicine, Department of Veterinary Clinical Sciences, Jordan University of Science and Technology, Irbid, - - 2014
To evaluate the effects of subarachnoid propofol administration (SPA) on analgesia, sedation, ataxia, cardiopulmonary, blood gas variables, and its application in ovariectomy in Jennies. Prospective, randomized, clinical trial. Adult Jennies (n = 20; 100-120 kg; 5-7 years old). In study 1, 5 Jennies had SPA (n = 5; group 1) through Tuohy catheter, and another ...
Baumunk Daniel D Department of Urology and Paediatric Urology, Magdeburg University Medical Centre, Magdeburg, - - 2014
Introduction: Radical retropubic prostatectomy (RRP) is associated with an increased risk of intraoperative blood loss and the necessity of transfusions. This prospective randomised clinical study evaluates the influence of thoracic epidural analgesia (TEA) on blood loss in RRP. Materials and Methods: 235 patients were randomised: TEA in group 1 (n ...
Stein M H MH Department of Anesthesia, Rutgers, The State University of New Jersey- Robert Wood Johnson Medical School, New Brunswick, New Jersey, - - 2014
Epidural blood patch is a standard treatment for obstetric patients experiencing a severe post-dural puncture headache. Patients who sustained an accidental dural puncture during establishment of epidural analgesia during labour or at caesarean delivery were randomly assigned to receive a prophylactic epidural blood patch or conservative treatment with a therapeutic ...
Fransen VAN DE Putte E E EE Department of Urology, Martini Hospital, Groningen, The - - 2014
Priapism is a rare complication of epidural anaesthesia, and the pathophysiology is poorly understood. In general, 95% of all priapism episodes is ischemic because of decreased penile blood flow, and therefore requires immediate treatment. A case is reported of a 45-year-old male patient in which a clear relation is demonstrated ...
Juebner Martin M Institute of Legal Medicine, University Hospital of Cologne, Melatengürtel 60/62, 50823, Cologne, Germany, - - 2014
Herein, we report a case of an assisted suicide committed by application of 34 matrix-based fentanyl-containing transdermal therapeutic systems (TTS) with different release rates. The TTS were supplied by the husband but administered by the deceased herself. Besides routine systematic toxicological analysis (STA), the concentrations of fentanyl and norfentanyl were ...
Bale Gemma G Biomedical Optics Research Laboratory, University College London, Malet Place Engineering Building, Gower St., London, WC1E6BT, UK, - - 2014
The relationship between cerebral autoregulation (CA) and the neurotoxic effects of anaesthesia with and without surgery is investigated. Newborn piglets were randomly assigned to receive either 6 h of anaesthesia (isoflurane) or the same with an additional hour of minor surgery. The effect of the spontaneous changes in mean arterial ...
Silva Aura A 0000-0002-2044-6320 Toxicology Department, REQUIMTE, Faculdade de Farmacia, Universidade do Porto, Rua de Jorge Viterbo Ferreira, No. 228, 4050-313 Porto, - - 2014
Bleeding changes the haemodynamics, compromising organ perfusion. In this study, the effects of bleeding followed by replacement with hydroxyethyl starch 130/0.4 (HES) or lactated Ringer's (LR) on cerebral oxygenation and electroencephalogram-derived parameters were investigated. Twelve young pigs under propofol-remifentanil anaesthesia were bled 30 mL/kg and, after a 20-minute waiting period, volume ...
Henderson Fraser - - 2013
This study determined the effects of the peripherally-restricted μ-opiate receptor (μ-OR) antagonist, naloxone methiodide (NLXmi) on fentanyl (25μg/kg, i.v.)-induced changes in (1) analgesia, (2) arterial blood gas chemistry (ABG) and Alveolar-arterial gradient (A-a gradient), and (3) ventilatory parameters, in conscious rats. The fentanyl-induced increase in analgesia was minimally affected by ...
Boonmak Polpun - - 2013
This is an update of a Cochrane Review first published in Issue 2, 2002. Dural puncture is a common procedure, but leakage of cerebrospinal fluid (CSF) from the resulting dural defect may cause post-dural puncture headache (PDPH) after the procedure, and this can be disabling. Injecting an epidural blood patch ...
Lucangelo Umberto - - 2013
During low-flow manually-controlled anaesthesia (MCA) the anaesthetist needs constantly adjust end-tidal oxygen (EtO2) and anaesthetic concentrations (EtAA) to assure an adequate and safe anaesthesia. Recently introduced anaesthetic machines can automatically maintain those variables at target values, avoiding the burden on the anaesthetist. End-tidal-controlled anaesthesia (EtCA) and MCA provided by the ...
Heesen Michael - - 2013
Postpartum haemorrhage (PPH) remains a leading cause of maternal morbidity and mortality. The odds for PPH were about eight times higher following general anaesthesia compared with neuraxial anaesthesia in a recent retrospective study. We aimed to conduct a systematic review and meta-analysis of the effect of type of anaesthesia (general ...
Garg Rakesh R Department of Anaesthesiology, Pain and Palliative Care, Dr. BRAIRCH, AIIMS, New Delhi, - - 2013
The technical advancement in the anaesthesia workstations has made the peri-operative anaesthesia more safer. Apart from other monitoring options, respiratory gas analysis has become an integral part of the modern anaesthesia workstations. Monitoring devices, such as an oxygen analyser with an audible alarm, carbon dioxide analyser, a vapour analyser, whenever ...
Shipley Kyle K Mallinckrodt Institute of Radiology, Washington University School of Medicine, St. Louis, Missouri, United - - 2014
Study Design Retrospective evaluation of consecutively performed fluoroscopically guided cervical nerve root blocks. Objective To describe the incidence of injectate central epidural flow with respect to needle tip position during fluoroscopically guided extraforaminal cervical nerve root blocks (ECNRBs). Methods Between February 19, 2003 and June 11, 2003, 132 consecutive fluoroscopically guided ECNRBs performed ...
Yang X-Y - - 2013
Few studies look into cerebral blood flow (CBF) changes during emergence from general anaesthesia for craniotomy. The purpose of this study was to assess CBF changes during emergence from general anaesthesia for craniotomy, through monitoring blood oxygen saturation of jugular vein bulb (SjvO2 ) and transcranial Doppler (TCD). We enrolled ...
Kokki M - - 2013
Postdural puncture headache is common in parturients following lumbar puncture. If headache is severe and persistent, an epidural blood patch is recommended. In this paper we reviewed the efficacy of epidural blood patches over a 13-year period at two hospitals in Finland with a particular emphasis on its timing. The ...
Hönemann Christian - - 2013
During the inhalation of anaesthesia use of low fresh gas flow (0.35-1 L/min) has some important advantages. There are three areas of benefit: pulmonary - anaesthesia with low fresh gas flow improves the dynamics of inhaled anaesthesia gas, increases mucociliary clearance, maintains body temperature and reduces water loss. Economic - ...
Lötsch Jörn - - 2013
Surrogates may provide easy and quick access to information about pharmacological parameters of interest that can be directly measured only with difficulty. Surrogates have been proposed for opioid blood concentrations to replace invasive sampling, serving as a basis for target-controlled infusion systems to optimize analgesia. We aimed at identifying surrogates ...
Benato L - - 2013
OBJECTIVES: Blood gas analysis is a well-recognized method to monitor pulmonary function, blood oxygenation, ventilation and acid-base status during general anaesthesia. The aim of this study was to report blood gas analysis results in pet rabbits (Oryctolagus cuniculus) obtained during general anaesthesia using a portable clinical analyser. METHODS: Thirty-two rabbits ...
Kumar Shruti - - 2013
Kasabach-Merritt syndrome is characterised by giant haemangioma, thrombocytopenia and coagulopathy. Triggering of disseminated intravascular coagulation along with the need for massive blood transfusion is the major intraoperative complication. A 1-month-old boy was scheduled for excision and split skin grafting of a giant haemangioma over the left thigh. Investigations revealed severe ...
Chaaban Mohamad R MR Department of Surgery, Section of Otolaryngology–Head and Neck Surgery, University of Chicago Medical Center, Chicago, IL, - - 2013
Total intravenous anesthesia (TIVA) with propofol has been associated with reduced operative time, decreased perioperative risks, and decreased intraoperative blood loss compared with inhalational anesthesia (IA). During endoscopic sinus surgery (ESS), reduced bleeding from the mucosal surfaces could improve visualization of the anatomy and decrease the risk of serious complications. ...
Tsui Ban - - 2013
BACKGROUND:Color flow Doppler ultrasonography has been used to confirm caudal epidural injection, but its ability to detect accidental intrathecal injection is unknown. We hypothesized that, when using color flow Doppler, the injection of fluid into the epidural space would result in turbulent flow which would appear as a burst of ...
Vassal O O Département Anesthésie-Réanimation, Hôpital Mère Enfant, Bron, - - 2013
Epidural blood patch is the standard treatment for postdural puncture headache when symptomatic therapy is ineffective. We report the cases of two patients who received an epidural injection of hydroxyethyl starch when an epidural blood patch was contraindicated; one due to Streptococcus agalactiae bacteraemia and one due to acute leukaemia. ...
Conroy Patrick H - - 2013
Tumescent anaesthesia describes the practice of injecting a very dilute solution of local anaesthetic combined with epinephrine and sodium bicarbonate into tissue until it becomes firm and tense (tumescent). It was initially described in the field of liposuction but now surgical applications for the technique are widely varied ranging across ...
Kudo Tomoyuki - - 2013
We have developed a new detection method of blood remifentanil concentration using a gas chromatography-mass spectrometry(GC-MS) with fentanyl as the internal standard(IS). The detection was performed at m/z 168 and 245 for remifentanil and fentanyl, respectively. In addition, the retention times of remifentanil and fentanyl were 5 min 45 s and 6 min ...
Kawano Hiroaki H Department of Anesthesiology and Clinical Research, National Hospital Organization Zentsuji Hospital, Zentsuji, Japan. - - 2013
Remifentanil enhances intraoperative hemodynamic stability, suggesting that it may decrease intraoperative blood loss when included as an adjuvant to general anesthesia. This retrospective study compared intraoperative blood loss during spinal surgery in patients administered either remifentanil or fentanyl as an opioid adjuvant. We reviewed clinical and surgical data from 64 ...
Pathak Darshan - - 2012
OBJECTIVES: Gastric tube necrosis is a major cause of mortality after oesophagectomy. The construction of the gastric tube used for oesophageal reconstruction involves a division of several arteries leading to a reduction in the blood supply at the fundus, which is used for the oesophageal anastomosis. This study was undertaken ...
Richards E R - - 2012
BACKGROUND: Thoracic epidural anaesthesia (TEA) is used widely in colorectal surgery. However, there is increasing concern that epidurals are associated with postoperative hypotension, mediating a potential reduction in splanchnic flow. The aim was to review the literature on the effects of TEA on splanchnic blood flow. METHODS: PubMed and Cochrane ...
Subramanian Arulselvi - - 2012
Over ordering of blood is a common practice in elective surgical practice. Considerable time and effort is spent on cross-matching for each patient undergoing a surgical procedure. The aim of this study was to compile and review the blood utilization for two key departments (Neurosurgery and Surgery) in a level ...
Medvedev Denis - - 2012
Aims: This pilot prospective, randomised, crossover study of positive aspiration frequency in intra-ligamental anaesthesia (ILA) was conducted with the following aims: (1) to determine the frequency of positive aspiration of blood after the administration of ILA at lower first molars, and (2) to evaluate the depth of the pulpal anaesthesia ...
Swanson Eric - - 2012
: Bupivacaine levels have not been measured in cosmetic surgery patients to establish safety. Blood loss has been underestimated using the small volumes present in the aspirate. The proportion of wetting solution removed by liposuction has not been reliably ascertained. : To remedy these deficiencies, a prospective study was undertaken ...
Shek Noel Wan Man - - 2012
Abstract Objective: To study fetal acid-base status and its implications under different modes of anaesthesia for caesarean sections. Methods: A prospective cohort study was conducted of 196 consecutive women with singleton non-anomalous fetuses who underwent either elective or emergency caesarean section after 36 completed weeks. Immediately after the baby was ...
Baron David M - - 2012
Interventions to increase brown adipose tissue (BAT) volume and activation are being extensively investigated as therapies to decrease the body weight in obese subjects. Noninvasive methods to monitor these therapies in animal models and humans are rare. We investigated whether contrast ultrasound (CU) performed in mice could detect BAT and ...
Post Ivo C J H - - 2012
Intra-organ flow is the most critical parameter in machine-perfused organ preservation systems (MPS). Ultrasonic flow sensors (UFS) are commonly employed in MPS. However, UFS are sensitive to changes in fluid composition and temperature and require recalibration. Novel Coriolis-type mass flow sensors (CFS) may be more suitable for MPS because the ...
Llorens Susana - - 2012
The aims of this paper are to test (1) the factorial structure of the frequency of flow experience at work; (2) the flow analysis model in work settings by differentiating the frequency of flow and the frequency of its prerequisites; and (3) whether there are significant differences in the frequency ...
Delp William Woody - - 2012
This study assessed the performance of seven new residential cooking exhaust hoods representing common U.S. designs. Laboratory tests were used to determine fan curves relating airflow to duct static pressure, sound levels, and exhaust gas capture efficiency for front or back cooktop burners or the oven. Airflow rate sensitivity to ...
Ranganathan Priya - - 2012
Allogenic blood transfusion is associated with several potential complications, especially in patients with cancer. The objective of this prospective single-centre study was to identify the rates of perioperative blood transfusion and overtransfusion in a tertiary-level cancer hospital. Between March and May 2008, we studied all adult patients undergoing elective major ...
Lam Garret C Y - - 2012
Although merging flow at duct junction is always encountered in fluid-transporting systems, previous works were mainly devoted to study the acoustics of duct junction but the aeroacoustics of flow merging has received little attention. Therefore, this paper aims at revealing the mechanism of sound generation by a merging flow at ...
Yun Zhao - - 2012
Air-modulated speaker is one of the most famous high-intensity sources. Sound waves with SPL above 160 dB are generated by the modulation of sonic air flow through a time-varying valve. To overcome the source saturation at high chamber pressures, the performance and flow characteristics of a new design, in which ...
Wujtewicz Maria M Department of Anaesthesiology and Intensive Therapy, Medical University of GdaƄsk. - - 2012
The aim of this study was to assess renal morbidity, associated with the use of low flow anaesthesia (LFA), in cancer patients previously treated with nephrotoxic chemotherapeutic agents. Seventy-five patients, aged 30-70 years, scheduled for elective surgery, were randomly allocated to three groups: Group A included those patients who had ...
Sinayoko Samuel - - 2012
An algorithm to compute the silent base flow sources of sound in a jet is introduced. The algorithm is based on spatiotemporal filtering of the flow field and is applicable to multifrequency sources. It is applied to an axisymmetric laminar jet and the resulting sources are validated successfully. The sources ...
Paisley Kevin K Department of Orthopaedic Surgery, Missouri Orthopaedic Institute, University of Missouri, Columbia, - - 2012
Study Design Retrospective analysis of lumbar computed tomographic epidurograms. Objective To evaluate the dispersal pattern of injectate after interlaminar lumbar epidural steroid injections. Summary Prior studies have evaluated the dispersal patterns of injectate after lumbar epidural steroid injections using fluoroscopy with varying results. To date, there have been no studies evaluating the dispersal ...
Calzetta Esteban - - 2012
We analyze a possible extension of Gioia and Chakraborty's momentum transfer model of friction in steady turbulent pipe flows [Phys. Rev. Lett. 96, 044502 (2006)] to the case of time- and/or space-dependent turbulent flows. The end result is an expression for the stress at the wall as the sum of ...
Kupisiak Jacek - - 2011
The need to reduce pollution emissions in the operating room and to reduce treatment costs motivates more frequent use of general anaesthesia with a small or minimal fresh gas flow rate. Nevertheless, the reduction of the delivery of fresh gases should not influence the quality and safety of the anaesthesia. ...
Bertalli Nadine A - - 2011
BACKGROUND: Questionnaire-based studies investigating blood donation history rely on the accurate recall of information from participants for results to be valid. This study aimed to retrieve electronic records from a national blood donation service and link them to self-reported history of donation to assess agreement between the two sources. STUDY ...
Sharma Vijay K - - 2011
Ultrasonography provides a unique diagnostic perspective in cerebrovascular disorders, with extremely high temporal resolution and excellent spatial display of extracranial as well as intracranial arteries. Unlike other imaging modalities, cerebrovascular ultrasound provides real-time information about the blood flow in addition to the hemodynamic changes as a result of various physiological ...
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