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Ansari Shazia Akbar SA Immunology and Infectious Diseases Research Laboratory, Department of Microbiology, University of Karachi, Karachi, - - 2014
A and B blood group antigens are fucosylated carbohydrate present on human erythrocytes and body secretions. Their presence in body secretions depends on the expression of a dominant allele of secretor gene FUT2 and is correlated with susceptibility to various infectious and non-infectious diseases. We investigated the correlation of blood ...
Sethi Sean K SK From the MRI Institute of Biomedical Research, Detroit, Michigan (SKS, DTU, - - 2014
To determine if extracranial venous structural and flow abnormalities exist in patients with multiple sclerosis (MS). Magnetic resonance imaging was used to assess the anatomy and function of major veins in the neck in 138 MS patients and 67 healthy controls (HC). Time-of-flight MR angiography (MRA) was used to assess ...
Liumbruno G M GM Immunohematology and Trasfusion Medicine, San Giovanni Calibita Fatebenefratelli Hospital,AFAR, Rome, Italy - - - 2014
The overall use of allogeneic blood transfusions in clinical practice remains relatively high and still varies widely among centres and practitioners. Moreover, allogeneic blood transfusions have historically been linked with risks and complications: some of them (e.g. transfusion reactions and transmission of pathogens) have been largely mitigated through advancements in ...
Ishizaki Yoichi Y Department of Hepatobiliary Pancreatic Surgery, Juntendo University School of Medicine, Tokyo, - - 2014
Background: There is little information on whether living donor liver transplantation (LDLT) reduces the supply of blood to esophagogastric varices. The aim of the present study was to assess the effects of LDLT on esophagogastric varices using both endoscopy and transendoscopic microvascular Doppler sonography (EMDS). Patients and Methods: 16 LDLT ...
Theusinger Oliver M OM Institute of Anesthesiology, University Hospital of Zurich, University of Zurich, Zurich, - - 2014
To point out the tolerance of anemia, the possible use of alternatives to allogeneic blood products as well as the pathophysiological effects of transfusions in the context of multiple trauma patients. Restrictive transfusion triggers are beneficial for patient outcome in trauma.The actual European Trauma Treatment Guidelines suggest the use of ...
Akgün Hakan H Neurology Service, Etimesgut Military Hospital, Etimesgut, Ankara, Turkey, - - 2014
Migraine is a neurovascular disorder characterized by autonomic nervous system dysfunction and severe headache attacks. Studies have shown that changes in the intracranial vessels during migraine have an important role in the pathophysiology. Many studies have been conducted on the increased risk of stroke in patients with migraine, but insufficient ...
Kim Hun H School of Mechanical Engineering, Yonsei University, 50 Yonsei-ro, Seodaemun-gu, Seoul 120-749, Republic of - - 2014
We recently introduced an optical sensor, termed photothermal spectral-domain optical coherence reflectometer (PT SD-OCR), capable of direct measurement of hemoglobin concentration ([Hb]) without chemicals and pre-processing of blood. PT SD-OCR measures [Hb] by quantifying refractive index changes of blood samples due to photothermal effect under the irradiation of 532-nm light. ...
Johansson Pär I PI Section for Transfusion Medicine, Capital Region Blood Bank, Copenhagen University Hospital, Rigshospitalet, Denmark; - - 2014
Massive hemorrhage is associated with coagulopathy and high mortality. The transfusion guidelines up to 2006 recommended that resuscitation of massive hemorrhage should occur in successive steps using crystalloids, colloids and red blood cells (RBC) in the early phase, and plasma and platelets in the late phase. With the introduction of ...
Hébert Paul C PC From the Canadian Critical Care Trials Group, Department of Medicine and Centre de Recherche, Centre Hospitalier de l'Université de Montréal (CRCHUM), Montreal (P.C.H.); and the Division of General Internal Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ - - 2014
Holst and colleagues(1) now provide definitive evidence in the Journal that a restrictive approach to blood transfusion not only reduced blood use by half but also did not cause harm to 998 critically ill patients with septic shock. It has been 15 years since the publication of the results of ...
Fragkou Paraskevi C - - 2014
IntroductionBlood transfusion in the peri-operative period has frequently been associated with an excess of nosocomial infections. Whilst transfused whole blood induces specific host immune alteration that may predispose to nosocomial infections, the immunomodulating properties associated with leukodepleted blood remain incompletely understood. In this study, we explore the hypothesis that the ...
Baron Joel J Department of Obstetrics and Gynecology, Soroka University Medical Center, Faculty of Health Sciences, Ben-Gurion University of the Negev, - - 2014
Abstract Objectives: To evaluate peak systolic velocimetry (PSV) in the umbilical artery (UA) among patients with single umbilical artery (SUA) as compared to patients with three vessel cords. Methods: A prospective case-control study was performed. UA blood flow velocimetry was obtained from fetuses with SUA and from a control group ...
Michot Jean-Marie JM Service de Médecine Interne et Immunologie Clinique, Assistance Publique-Hôpitaux de Paris, Hôpital Universitaire Bicêtre, Le Kremlin-Bicêtre, France; Université Paris Sud 11, Le Kremlin-Bicêtre, - - 2014
Sickle cell disease (SCD) has become a major public health issue. Hydroxyurea and red blood cell (RBC) transfusion are the cornerstone treatments. Erythrocytapheresis (ECP) is an automated method for transfusion exchange. Given that ECP requires more blood than conventional transfusion, there is concern about alloimmunization and hemolytic transfusion reactions. We ...
Garcia Julio J Department of Radiology, Northwestern University, Chicago, - - 2014
To test the feasibility of velocity distribution analysis for identifying altered three-dimensional (3D) flow characteristics in patients with aortic disease based on 4D flow MRI volumetric analysis. Forty patients with aortic (Ao) dilation (mid ascending aortic diameter MAA = 40 ± 7 mm, age = 56 ± 17 years, 11 females) underwent cardiovascular MRI. Four groups were retrospectively ...
Moseley Brian D BD Department of Neurology and Rehabilitation Medicine, University of Cincinnati, Cincinnati, OH, USA. Electronic address: - - 2014
Based on previous fMRI and SPECT studies, it has been suggested seizures may be preceded by increased cerebral blood flow. Recently, we demonstrated transcutaneous regional cerebral oxygen saturation (rSO2) sensors are feasible for use in patients undergoing video EEG monitoring. We reanalyzed our data to determine if seizures were consistently ...
Saleh Anas A Department of Orthopaedic Surgery, Mail Code A41, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195. E-mail address for A.K. Klika: - - 2014
The large-scale utilization of allogenic blood transfusion and its associated outcomes have been described in critically ill patients and those undergoing high-risk cardiac surgery but not in patients undergoing elective total hip arthroplasty. The objective of this study was to determine the trends in utilization and outcomes of allogenic blood ...
Kredel Markus M * University of Würzburg, Department of Anaesthesia and Critical Care, Würzburg, Germany † University Medical Center Regensburg, Department of Internal Medicine II, Regensburg, Germany ‡ University of Würzburg, Department of Neurosurgery, Würzburg, Germany § University Medical Center Regensburg, Department of Cardiothoracic Surgery, Regensburg, Germany ¶ Equally contributing - - 2014
In an acute respiratory distress syndrome (ARDS) venovenous extracorporeal membrane oxygenation (vvECMO) can rapidly normalize arterial hypoxemia and carbon dioxide tension (PaCO2). Considering the positive relationship between PaCO2 and cerebral blood flow, the aim of the current study was to evaluate cerebral regional tissue oxygen saturation (rSO2) during the implementation ...
Sandek Anja A Division of Applied Cachexia Research, Department of Cardiology, Charité, Campus Virchow, Berlin, Germany; Department of Cardiology, Charité Medical School, Campus Virchow-Klinikum, Berlin, Germany. Electronic address: - - 2014
Blood flow in the intestinal arteries is reduced in patients with stable heart failure (HF) and relates to gastrointestinal (GI) symptoms and cardiac cachexia. The aims of this study were to measure arterial intestinal blood flow and assess its role in juxtamucosal bacterial growth, GI symptoms, and cachexia in patients ...
Shakur Sophia F SF From the Department of Neurosurgery, University of Illinois at - - 2014
The hemodynamic effects of extracranial carotid stenosis on intracranial blood flow are not well characterized. We sought to determine the impact of degree of stenosis, stenosis length, and residual lumen on intracranial blood flow in patients with extracranial carotid stenosis. Carotid stenosis patients who had undergone both vessel flow rate ...
Lavinskiene Simona S Department of Pulmonology and Immunology, Lithuanian University of Health Sciences, Kaunas, Lithuania, - - 2014
The aim of this study was to estimate relations between sputum neutrophilia and the chemotactic activity of peripheral blood neutrophils after the bronchial allergen challenge in asthma patients. Fifteen patients with allergic asthma (AA), 13 patients with allergic rhinitis (AR), all sensitized to Dermatophagoides pteronyssinus, and 8 healthy subjects (HS) ...
Gentile Mauro M Neurologic Clinic, University of Ferrara, Ferrara, Italy. Electronic address: - - 2014
Contrast-transcranial Doppler and contrast-transcranial color-coded duplex sonography (c-TCCD) have been reported to have high sensitivity in detecting patent foramen ovale as compared with transesophageal echocardiography. An international consensus meeting (Jauss and Zanette 2000) recommended that the contrast agent for right-to left-shunt (RLS) detection using contrast-transcranial Doppler be prepared by mixing ...
Ries Jutta J Department of Oral and Maxillofacial Surgery, Erlangen University Hospital, Erlangen, Germany - - 2014
Background/Aim: Aberrant microRNA (miRNA) expression in blood of cancer patients is a common finding. The present study aimed at evaluating the differences in miRNA expression in whole blood samples of oral squamous cell carcinoma (OSCC) patients compared to healthy controls. Materials and Methods: Microarray based miRNA profiling was performed on ...
Leli Christian C From the Microbiology Section, Department of Experimental Medicine, University of Perugia, Santa Maria della Misericordia Hospital , Perugia , - - 2014
Background: Procalcitonin (PCT) levels can be used to predict bacteremia and DNAemia in patients with sepsis. In this study, the diagnostic accuracy of PCT in predicting blood culture (BC) results and DNAemia, as detected by real-time PCR (RT-PCR), was compared with that of other markers of inflammation commonly evaluated in ...
Fujii Toshiharu T Department of Cardiology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, 259-1193, - - 2014
Routine use of distal protection for ST-segment elevation myocardial infarction (STEMI) is not recommended. The purpose of this study was to analyze the impact of slow flow on mortality after STEMI, and the efficacy of adjunctive distal protection following primary thrombus aspiration. We retrospectively analyzed 414 STEMI patients who underwent ...
Arellano Daniel L DL Division of Critical Care, Department of Medicine, Houston Methodist Hospital, 6550 Fannin Street, Suite SM1001, Houston, TX 77030, USA; Department of Family Health, School of Nursing, University of Texas Health Science Center at Houston, Room# 796, 6901 Bertner Avenue, Houston, TX 77030, USA. Electronic address: - - 2014
The purpose of this article is to propose optimal weaning of vasopressors in patients with septic shock. Topics discussed include pathophysiology of sepsis and septic shock, treatment guidelines for sepsis, autoregulation of blood flow, vasopressors used in septic shock, weaning recommendations, monitor alarms in the intensive care unit, and new ...
Soylu Korhan K Korhan Soylu, MD, Assistant Professor, Department of Cardiology, Faculty of Medicine, Ondokuz Mayis University, Samsun, - - 2014
The coronary slow flow phenomenon (CSFP) is a coronary artery disease with a benign course, but its pathological mechanisms are not yet fully understood.The purpose of this controlled study was to investigate the cellular content of blood in patients diagnosed with CSFP and the relationship of this with coronary flow ...
Lagana Maria Marcella MM Fondazione Don Carlo Gnocchi ONLUS IRCCS S. Maria Nascente, Milan, Italy Italy. - - 2014
We studied cerebrospinal fluid (CSF) flow dynamics at the cervical level in association with internal jugular veins (IJV) flow for 92 patients with multiple sclerosis (MS). Phase contrast magnetic resonance imaging was used to quantify flow of the CSF and major vessels (including the IJV and the carotid arteries) at ...
Lyra Juliana Maria Azevedo de JM Departamento de Imunologia, Centro de Pesquisas Aggeu Magalhães-Fiocruz, Recife, PE, - - 2014
The present study analysed the concordance among four different molecular diagnostic methods for tuberculosis (TB) in pulmonary and blood samples from immunocompromised patients. A total of 165 blood and 194 sputum samples were collected from 181 human immunodeficiency virus (HIV)-infected patients with upper respiratory complaints, regardless of suspicious for TB. ...
Era Sumiko S Center for Maternal, Fetal and Neonatal Medicine, Saitama Medical Center, Saitama Medical University, Kawagoe, - - 2014
Massive obstetric hemorrhage (MOH) requires prompt transfusion of red blood cells and coagulation factors. Because MOH has a diverse pathogenesis, the shock index (SI) alone may be insufficient for determining blood transfusion. Here, we retrospectively analyzed patients with MOH to determine usefulness of the indicators of shock including the SI ...
Cornwell William K WK 3rd Institute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital, Dallas, Texas; Department of Internal Medicine, Division of Cardiology, University of Texas Southwestern Medical Center, Dallas, - - 2014
Insertion of a left ventricular assist device (LVAD) is an accepted therapy for advanced heart failure patients. However, the effects on end-organ perfusion, including cerebral autoregulation, are unclear in the presence of reduced pulsatility. Therefore, the objective of this study was to determine whether cerebral autoregulation is impaired in patients ...
Hou Guojin G Department of Orthopaedic Surgery, Peking University Third Hospital, No 49, North Garden Rd, HaiDian District, Beijing 100191, China. Electronic address: - - 2014
The need exists for perioperative blood management measures aimed at improving patient outcomes and reducing the risks of allogeneic blood transfusion (ABT). Our study aim is to discuss an algorithm to predict the need for perioperative blood transfusion in old patients with pertrochanteric femoral fractures. We retrospectively analysed the data ...
Salisbury Adam C AC Department of Cardiology, Saint Luke's Mid America Heart Institute, Kansas City, Missouri; University of Missouri-Kansas City School of Medicine, Kansas City, Missouri. Electronic address: - - 2014
Blood transfusion is controversial for anemic patients with acute myocardial infarction (AMI), with some previous studies reporting increased risk of transfusion-associated mortality. The goal of this study was to examine variability in blood transfusions across hospitals and the relationship between blood transfusion and in-hospital mortality in a large, contemporary cohort ...
Komatsu Ryu R Anesthesiology Institute, Cleveland Clinic, 9500 Euclid Ave.,/E30, Cleveland, OH, 44195 USA. Electronic address: - - 2014
To investigate whether Type O blood group status is associated with increased intraoperative blood loss and requirement of blood transfusion in extensive spine surgery. Retrospective comparative study. University-affiliated, non-profit teaching hospital. Data from 1,050 ASA physical status 1, 2, 3, 4, and 5 patients who underwent spine surgeries involving 4 ...
Meijs Jessica J Department of Rheumatology, Leiden University Medical Center, Leiden, Department of Rheumatology, VU University Medical Center, Amsterdam, Medical Department, Actelion Pharmaceuticals Nederland BV, Woerden and Department of Rheumatic Diseases, Radboud University Medical Centre, Nijmegen, The Netherlands. - - 2014
The aim of the study was to examine the effect of bosentan on blood flow in the hand in a subset of patients who had reduced blood flow relative to healthy subjects. Additionally, the relationship between blood flow in the hands of SSc patients and the presence of digital ulcers ...
Tsao Yu-Chien YC Department of Internal Medicine, Yonghe Cardinal Tien Hospital, Taipei 234, Taiwan; Department of Neurology, Neurological Institute, Taipei Veterans General Hospital, Taipei 11217, Taiwan; School of Medicine, National Yang-Ming University, Taipei 11217, - - 2014
Panic disorder (PD) is characterized by panic attacks accompanied with respiratory symptoms. Internal jugular vein (IJV) alters its hemodynamics in response to respiration and which might cause cerebral blood flow (CBF) changes. In the present study, we compared (1) respiratory-related IJV hemodynamics and (2) CBF changes during Valsalva maneuver (VM) ...
Chou Chiu-Wen CW Department of Anesthesiology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China. Electronic address: - - 2014
Perioperative blood transfusion still takes a large proportion in inappropriate blood transfusion. As the data are limited in China, we reported a perioperative red blood cell (RBC) transfusion practices in a tertiary hospital in Guangzhou, China. In 2008-2009, patients who underwent elective surgeries receiving RBC transfusions were recorded and the ...
Geeraedts Leo M G LM Jr Department of Surgery and Institute for Cardiovascular Research, VU University Medical Center, De Boelelaan 1117, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands; Helicopter Emergency Medical Service, Northwestern Netherlands Trauma Area, VU University Medical Center, De Boelelaan 1117, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands. Electronic address: - - 2014
The ideal strategy for prehospital intravenous fluid resuscitation in trauma remains unclear. Fluid resuscitation may reverse shock but aggravate bleeding by raising blood pressure and haemodilution. We examined the effect of prehospital i.v. fluid on the physiologic status and need for blood transfusion in hypotensive trauma patients after their arrival ...
Wehry John J Division of Surgical Oncology, Department of Surgery, University of Louisville, 315 E. Broadway #312, Louisville, KY 40202, - - 2014
Management of anemia in surgical oncology patients remains one of the key quality components in overall care and cost. Continued reports demonstrate the effects of hospital transfusion, which has been demonstrated to lead to a longer length of stay, more complications, and possibly worse overall oncologic outcomes. The hypothesis for ...
Ali Muhammad Asghar MA Department of Anaesthesia, The Aga Khan University Hospital, - - 2014
Bombay blood group is a rare autosomal recessive phenotype within the ABO blood group. It represents genetically suppressed A, B and H genes. When considering such patients for transfusion, only blood of identical Bombay type can be safely transfused. We are reporting a patient having Bombay phenotypic blood, underwent emergency ...
Krinsky Clarissa S CS University of New Mexico Health Sciences Center, New Mexico Office of the Medical Investigator, MSC07 4040, 1 University of New Mexico, Albuquerque, NM, - - 2014
Fentanyl is a synthetic opioid agonist used for pain control. Often administered as a transdermal patch, it is an interesting drug for study of postmortem redistribution. We hypothesized that fentanyl concentrations would increase over time after death, as measured in blood drawn on the day prior to autopsy and in ...
Moore Philip W PW Department of Internal Medicine, PinnacleHealth Hospitalists, 111 S. Front St, Harrisburg, PA, 17101; Department of Internal Medicine, PinnacleHealth Toxicology Center, 111 S. Front St, Harrisburg, PA, 17101; Department of Emergency Medicine, Penn State University College of Medicine, 500 University Dr, Hershey, PA, - - 2014
Opioid-related mortality happens, even in healthcare settings. We describe serial postmortem fentanyl blood concentrations in a hospital inpatient who fatally abused transdermal fentanyl. This is a single-patient case report. A 42-year-old man with lymphoma was started on transdermal fentanyl therapy while hospitalized for chronic abdominal pain. The patient was last ...
Spada Eva E Veterinary Transfusion Unit (REV), Department of Health, Animal Science and Food Safety (VESPA), University of Milan, Milan, Italy - - 2014
This prospective study investigated the effect on clinical and haematological variables of the anaesthetic combination of tiletamine and zolezapam in feline blood donors. Blood (10 ml/kg bodyweight to a maximum volume of 60 ml) was collected from the jugular vein of 31 owned healthy cats anaesthetised with 2.5 mg/kg of ...
Chen X X Department of Biomedical Engineering, Key Laboratory of Biomedical Engineering of Ministry of Education of China, Zhejiang University, Hangzhou, Zhejiang, - - 2014
Although pilot studies have reported that exhaled propofol concentrations can reflect intraoperative plasma propofol concentrations in an individual, the blood/exhaled partial pressure ratio RBE varies between patients, and the relevant factors have not yet been clearly addressed. No efficient method has been reported for the quick evaluation of RBE and ...
Mergan Zara Y ZY Department of Anesthesiology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, - - 2014
We present a case of a patient with acute lymphoblastic leukemia (ALL) undergoing an epidural blood patch (EBP) for post-puncture dural headaches despite the risks of spreading cancer cells to the epidural space. A 46-year-old male with a history of adult T-cell ALL presented with persistent positional headache and neutropenic ...
Wiszniewski Dawid D Department of Intensive Therapy and Anaesthesiology, II Chair of Paediatrics, Maria Konopnicka Teaching Hospital No. 4 in Łódz, Medical University of Łódź, Poland. - - 2014
enous malformations are the second most common congenital vessel anomaly. In our hospital, we conduct up to 30 sclerotherapies with 1-3% aethoxysclerol annually in children of all ages. The procedure is invasive and painful and therefore requires general anaesthesia. A 16-year-old girl underwent sclerotherapy of a vast vascular malformation of ...
Das Sudipta Sekhar SS Department of Transfusion Medicine, Apollo Gleneagles Hospitals, Kolkata, West Bengal, - - 2014
Autoimmune hemolytic anemia (AIHA) is characterized by the production of autoantibodies directed against red cell antigens. Most patients of AIHA arrive in the emergency or out-patient department (OPD) with severe anemia requiring urgent blood transfusion. Here we share our experience of managing these patients with incompatible blood transfusions and suggest ...
Dhawan Hari Krishan HK Department of Transfusion Medicine, PGIMER, Chandigarh, - - 2014
The development of anti-red blood cell antibodies (both allo-and autoantibodies) remains a major problem in thalassemia major patients. We studied the frequency of red blood cell (RBC) alloimmunization and autoimmunization among thalassemia patients who received regular transfusions at our center and analyzed the factors, which may be responsible for development ...
G Suresh S Reader, Department of Oral Medicine and Radiology, Sibar Institute of Dental Sciences , Guntur, India - - 2014
To determine correlation between the Salivary Urea levels with that of Blood Urea levels. Subjects were selected from patients undergoing haemodialysis and patients who had underwent kidney transplantation at Ashwini Hospitals Guntur. The study comprised of 45 patients, of which Haemodialysis group (HD) with 20 patients, Transplant (T) group with ...
Prabhakar Hemanshu H Department of Neuroanaesthesiology, Neurosciences Centre, All India Institute of Medical Sciences, PGIMER, Chandigarh, - - 2014
Traumatic brain injury (TBI) consists of varied pathophysiological consequences and alteration of intracranial dynamics, reduction of the cerebral blood flow and oxygenation. In the past decade more emphasis has been directed towards optimizing cerebral perfusion pressure (CPP) in patients who have suffered TBI. Injured brain may show signs of ischemia ...
Matoshvili M M Tbilisi State Medical University, Department of Dermatology and Venereology, Department of Medical Physics and Biophysics, Department of Human Normal Anatomy, Georgia; University of Rome "Sapienza", Department of Dermatology and Venereology, - - 2014
The skin is constantly exposed to oxidative stress induced by reactive oxygen species (ROS) that are generated both from endogenous neutrophils and external pro-oxidant stimuli. The present study was planned to investigate the possible involvement of free radical oxidation in psoriatic patients. Study was carried out in the Department of ...
Pape Andreas A From the Department of Anesthesiology, Intensive-Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt am Main, Germany (A.P., C.F.W., M.L., M.S., S.K., O. Horn); Clinic of Anesthesiology, Ludwig Maximilians University Hospital, Munich, Germany (B.Z.); and Clinic of Anesthesiology, Surgical Intensive Care Medicine and Pain Management, Krankenhaus Nordwest, Frankfurt, Germany (O. - - 2014
The initial treatment of an acute blood loss with acellular fluids leads to the dilution of the red cell mass remaining in the vasculature, that is, to acute normovolemic anemia. Whether the compensation and, thus, the tolerance of acute anemia, are affected by sympathetic block induced by thoracic epidural anesthesia ...
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