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Izumi Yasukatsu Y Department of Pharmacology, Osaka City University Medical - - 2014
Aim: Highly concentrated carbon dioxide (CO2) is thought to be useful for ischemic diseases. We investigated whether treatment with a few micrometers of CO2 molecules atomized via two fluidnozzles (CO2 mist) exerts an angiogenic effect in a mouse ischemic hindlimb model. Methods: Mice with unilateral hindlimb ischemia were divided into ...
Moody Cm C Animal Welfare Program, Faculty of Land and Food Systems, University of British Columbia, Vancouver, - - 2014
Laboratory rodents are commonly euthanized by exposure to gradually increasing concentrations of carbon dioxide (CO2). Current recommended flow rates range between 10 and 30% chamber vol/min and result in insensibility before exposure to painful concentrations (<40%). However, this method causes dyspnea, indicated by deep, rapid breathing. In humans dyspnea is ...
Cater John E JE Department of Engineering Science, The University of Auckland, Private Bag 92019, Auckland 1142, New Zealand. Electronic address: - - 2014
Flow within a model surgical opening during insufflation with heated carbon dioxide was studied using computational fluid dynamics. A volume of fluid method was used to simulate the mixture of ambient air and carbon dioxide gas. The negative buoyancy of the carbon dioxide caused it to fill the wound and ...
Selleri Paolo P Clinic for Exotic Animals, Veterinary Specialty Center, Rome, Italy (P.S., N.D.) and Department of Veterinary Medical Sciences, University of Bologna, Ozzano Emilia, Italy - - 2014
Point-of-care testing is an attractive option in rabbit medicine, because it permits rapid analysis of a panel of electrolytes, chemistries, blood gases, hemoglobin, and hematocrit, requiring only 65 μL of blood. The purpose of this study was to evaluate the performance of a portable clinical analyzer for measurement of pH, ...
Coverdale Nicole S NS Western - - 2014
To establish the accuracy of transcranial Doppler ultrasound (TCD) measures of middle cerebral artery (MCA) cerebral blood flow velocity (CBFV) as a surrogate of cerebral blood flow (CBF) during hypercapnia (HC) and hypocapnia (HO) we examined whether the cross-sectional area (CSA) of the MCA changed during HC or HO and ...
Shahidi Ayda M AM Department of Ophthalmology and Vision Science, Toronto Western Research Institute, Toronto, Ontario, Canada School of Optometry and Vision Science, University of Waterloo, Waterloo, Ontario, - - 2014
The purpose of this study was to investigate changes in total retinal blood flow (RBF) using Doppler Fourier Domain Optical Coherence Tomography (Doppler FD-OCT) in response to the manipulation of systemic partial pressure of CO2 (PETCO2). Double circular Doppler blood flow scans were captured in nine healthy individuals (mean age ...
Sato Kohei K Research Institute of Physical Fitness, Japan Women's College of Physical Education, Tokyo, - - 2014
Recent studies have suggested that vertebral artery (VA) hypoplasia is a predisposing factor for posterior cerebral stroke. We examined whether anatomical vertebrobasilar ischemia, i.e., unilateral VA hypoplasia and insufficiency, impairs dynamic blood flow regulation. Twenty-eight female subjects were divided into three groups by defined criteria: (i) unilateral VA hypoplasia (n = 8), ...
Harter T S TS Department of Zoology, University of British Columbia, 6270 University Boulevard, Vancouver, BC, V6T 1Z4, Canada, - - 2014
Preferential intracellular pH (pHi) regulation, where pHi is tightly regulated in the face of a blood acidosis, has been observed in a few species of fish, but only during elevated blood PCO2. To determine whether preferential pHi regulation may represent a general pattern for acid-base regulation during other pH disturbances ...
Wu Jie J Department of Chemistry, Massachusetts Institute of Technology, 77 Massachusetts Ave., Cambridge, MA 02139 - - 2014
We describe an efficient continuous flow synthesis of ketones from CO2 and organolithium or Grignard reagents that exhibits significant advantages over conventional batch conditions in suppressing undesired symmetric ketone and tertiary alcohol byproducts. We observed an unprecedented solvent-dependence of the organolithium reactivity, the key factor in governing selectivity during the ...
Karagiannidis Christian - - 2014
While non-invasive ventilation aimed at avoiding intubation has become the modality of choice to treat mild to moderate acute respiratory acidosis, many severely acidotic patients (pH <7.20) still need intubation. Extracorporeal veno-venous CO2 removal (ECCO2R) could prove to be an alternative. The present animal study tested in a systematic fashion ...
Rettenmund Christy L - - 2014
Point of care devices can assess electrolyte, blood gas, biochemical, and hematologic values in a critical care setting. Although these devices are commonly used in humans and companion mammals, few studies have assessed their use in avian species. This study compares electrolyte, hemoglobin (Hgb), hematocrit (Hct), acid-base, and venous blood ...
Friedrich Benjamin B Institute for Surgical Research, University of Munich Medical Center, Munich, - - 2014
In addition to delayed vasospasm also early brain injury, which occurs during the first few days after subarachnoid hemorrhage (SAH) when large cerebral arteries are still fully functional, plays an important role for the outcome after SAH. In the current study, we investigated the hypothesis that carbon dioxide (CO2), a ...
Victor Suresh S 1] Institute of Human Development, University of Manchester, Manchester, United Kingdom [2] Central Manchester University Hospitals NHS Foundation Trust, The Manchester Academic Health Sciences Centre, Manchester, United - - 2014
Introduction:Permissive hypercapnia is routinely practiced on neonatal intensive care units. The effect of permissive hypercapnia on the preterm brain and brain electrical activity is unknown. In this study, we aimed to determine the effect of chronic changes in partial pressure of blood carbon dioxide (PCO2) on brain electrical activity in ...
Bhogal Alex A Department of Radiology, University Medical Center Utrecht , H.P. E 01.132, Heidelberglaan 100, 3584 CX Utrecht. Electronic address: - - 2014
Cerebrovascular reactivity (CVR) is a mechanism responsible for maintaining stable perfusion pressure within the brain via smooth muscle mediated modulations of vascular tone. The amplitude of cerebral blood flow (CBF) change in response to a stimulus has been evaluated using Blood Oxygen Level Dependent (BOLD) MRI, however the relationship between ...
Matos Juan J Department of Photocatalysis and Alternative Energies, Venezuelan Institute for Scientific Research (IVIC), 20632, Caracas, 1020-A, Venezuela, - - 2014
Photodegradation of methylene blue (MB) was studied on TiO2 in the presence of activated carbon (AC) prepared from the sawdust of a soft wood by physical activation under CO2 flow, by pyrolysis under N2 flow, and by chemical activation with ZnCl2 and H3PO4 under N2 flow. MB photodegradation was performed ...
Ogoh Shigehiko S 1Toyo - - 2014
The purpose of this study was to assess blood flow responses to changes in carbon dioxide (CO2) in the internal carotid artery (ICA), external carotid artery (ECA) and vertebral artery (VA) during normothermic and hyperthermic conditions. Eleven healthy subjects aged 22±2 (SD) years were exposed to passive whole body heating ...
Culp William C WC Jr From the Department of Anesthesiology, Texas A&M University Health Science Center College of Medicine, Scott & White Hospital, Temple, - - 2014
Operating room fires are sentinel events that present a real danger to surgical patients and occur at least as frequently as wrong-sided surgery. For fire to occur, the 3 points of the fire triad must be present: an oxidizer, an ignition source, and fuel source. The electrosurgical unit (ESU) pencil ...
Yang Jiachen - - 2014
End-tidal carbon dioxide (P<sub>ET</sub>CO<sub>2</sub>) monitoring has become an important tool in clinical monitoring, but there are still limitations in practice. Low-frequency modulation was used to reliably acquire respiratory information. Then the disturbances of humidity and flow rate were removed by signal decomposition. Finally, the real-time concentration of CO<sub>2</sub> was calculated ...
Marmarelis V Z VZ Department of Biomedical Engineering & Biomedical Simulations Resource, University of Southern California, United States. Electronic address: - - 2014
In our previous studies, we have introduced model-based "functional biomarkers" or "physiomarkers" of cerebral hemodynamics that hold promise for improved diagnosis of early-stage Alzheimer's disease (AD). The advocated methodology utilizes subject-specific data-based dynamic nonlinear models of cerebral hemodynamics to compute indices (serving as possible diagnostic physiomarkers) that quantify the state ...
Noori Shahab S Division of Neonatology and the Center for Fetal and Neonatal Medicine, Department of Pediatrics, Children's Hospital Los Angeles and the LAC+USC Medical Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, United - - 2014
High arterial carbon dioxide (PaCO2 ) and cerebral reperfusion are associated with peri/intraventricular haemorrhage. Our aim was to study the relationship between PaCO2 and cerebral blood flow (CBF) in preterm infants during postnatal transition. We prospectively studied ≤30 weeks' gestation haemodynamically stable preterm infants during the first three postnatal days ...
Caputi Luigi L Department of Cerebrovascular Diseases, Fondazione IRCCS Neurological Institute C. Besta, Via Celoria 11, 20133 Milan, Italy. Electronic address: - - 2014
Assessment of cerebrovascular reactivity (CVR) is essential in cerebrovascular diseases, as exhausted CVR may enhance the risk of cerebral ischemic events. Transcranial Doppler (TCD) with a vasodilatory stimulus is currently used for CVR evaluation. Scanty data are available for Quantitative Magnetic Resonance Angiography (QMRA), which supplies higher spatial resolution and ...
Belenkiy Slava M SM 1United States Army Institute of Surgical Research, Fort Sam Houston, Texas 2San Antonio Military Medical Center, Fort Sam Houston, - - 2014
Hemorrhagic shock (HS) is a setting in which both pulmonary and cutaneous perfusion may be impaired. The goals of this study were (1) to evaluate the relationship between end-tidal (etCO2), transcutaneous (tPCO2), arterial carbon dioxide (PaCO2), and lactate during lethal HS; and (2) to assess the effect of progressive HS ...
Strohm J J Department of Medical and Life Sciences, Hochschule Furtwangen University, - - 2014
Cerebrovascular reactivity (CVR) assesses the ability of the cerebral vasculature to adjust cerebral blood flow in response to changes in arterial carbon dioxide (CO2), and is used as an indicator of cerebrovascular health. A common method of estimating CVR is to measure the increase in blood flow velocity of the ...
Scaravilli Vittorio V *) U.S. Army Institute of Surgical Research, Fort Sam Houston, San Antonio TX, USA †) Department of Experimental Medicine, University Milano-Bicocca, Monza (MB), Italy ‡) Department of Perioperative Medicine and Intensive Care, San Gerardo Hospital, Monza (MB), Italy §) Department of Anesthesiology and Intensive Care Medicine, University Hospital Bonn, Bonn, Germany ¶) Pediatric Department, University Hospital Bonn, Bonn, Germany &) San Antonio Military Medical Center, San Antonio TX, - - 2014
The combination of extracorporeal carbon dioxide removal (ECCO2R) and hemofiltration is a possible therapeutic strategy for patients needing both lung and renal support. We tested the effects of the recirculation of ultrafiltrate on membrane lung (ML) CO2 removal (VCO2ML).Three conscious, spontaneously breathing sheep were connected to a commercially produced ECCO2R ...
Kamath Rahul R - - 2014
Three-dimensional (3D) carbon interdigitated electrode arrays (IDEAs) were fabricated using inexpensive, conventional, UV photolithography of SU-8 with modified exposure and post exposure bake settings followed by pyrolysis in an inert environment. The sensor performance was investigated as a function of both the IDEA digit width/gap ratio and digit height under ...
Battilocchio Claudio C Innovative Technology Centre, Department of Chemistry, University of Cambridge , Lensfield Road, CB2 1EW, Cambridge - - 2014
A sustainable flow chemistry process for the hydration of nitriles, whereby an aqueous solution of the nitrile is passed through a column containing commercially available amorphous manganese dioxide, has been developed. The product is obtained simply by concentration of the output stream without any other workup steps. The protocol described ...
Pereira A D AD Departamento de Nutrição, Universidade Federal do Tocantins, CEP, 77001-090 Palmas, TO, - - 2014
The proximate composition and color of mortadellas containing carbon monoxide-treated (COTB), untreated (UNTB), or CO-treated dried blood (CODB) were compared to that of control mortadella. Blood addition did not affect (P>0.05) the proximate composition and TBARS. The mortadella containing 10% UNTB were brown and those containing COTB or CODB were ...
Song Yongchen Y Key Laboratory of Ocean Energy Utilization and Energy Conservation of Ministry of Education, Dalian University of Technology, Dalian, Liaoning 116024 - - 2014
The objective of this study was to understand fluid flow in porous media. Understanding of fluid flow process in porous media is important for the geological storage of CO2. The high-resolution magnetic resonance imaging (MRI) technique was used to measure fluid flow in a porous medium (glass beads BZ-02). First, ...
Zanella Alberto A From the Dipartimento di Scienze della Salute, Università di Milano-Bicocca, Ospedale San Gerardo Nuovo dei Tintori, Monza, Italy (A.Z., P.M., S.R., V.S., M.G., D.F., N.P., and A.P.); Dipartimento di Patologia animale, Igiene e Sanità pubblica veterinaria, sez. di Biochimica e Fisiologia, Università degli studi di Milano, Milan, Italy (F.P. and M.A.); and Dipartimento di Scienze Farmacologiche e Biomolecolari (DiSFeB), Scuola di Scienze del Farmaco, Università degli studi di Milano, Milan, Italy - - 2014
Extracorporeal carbon dioxide removal has been proposed to achieve protective ventilation in patients at risk for ventilator-induced lung injury. In an acute study, the authors previously described an extracorporeal carbon dioxide removal technique enhanced by regional extracorporeal blood acidification. The current study evaluates efficacy and feasibility of such technology applied ...
Kennedy Rr R Department of Anaesthesia, Christchurch Hospital, Christchurch, New - - 2014
Reducing fresh gas flow (FGF) rates with volatile anaesthetics reduces waste, with positive financial and environmental consequences. We have audited FGF since 2001 by analysis of data collected from anaesthetic machines. We recently introduced Aisys(®) (GE Healthcare, Madison, WI, USA) machines that allow automated control of end-tidal levels of volatile ...
Maggio Paola P Neurologia Clinica, Università Campus Bio-Medico, Rome, - - 2014
Abstract PaCO2 affects cerebral blood flow (CBF) and its regulatory mechanisms, but the interaction between neurovascular coupling (NVC), cerebral autoregulation (CA), and cerebrovascular reactivity to CO2 (CVR), in response to hypercapnia, is not known. Recordings of cerebral blood flow velocity (CBFv), blood pressure (BP), heart rate, and end-tidal CO2 (EtCO2) ...
Blässer Katharina K Institute of Legal Medicine, Julius-Maximilians-Universität Würzburg, Versbacher Straße 3, 97078 Würzburg, Germany. Electronic address: - - 2013
The presented case deals with an unusual suicide by carbon monoxide poisoning. In a car parked in a highway rest area, the body of a middle-aged man was found. In the open trunk of the car there was a gas-powered generator which was switched on, but no longer running. The ...
Zanella Alberto A Dipartimento di Scienze della Salute, Università di Milano-Bicocca, Ospedale San Gerardo Nuovo dei Tintori, Monza, - - 2013
Extracorporeal (EC) carbon dioxide (CO2) removal (ECCO2R) may be a powerful alternative to ventilation, possibly avoiding the need for mechanical ventilation and endotracheal intubation. We previously reported how an infusion of lactic acid before a membrane lung (ML) effectively enhances ECCO2R. We evaluated an innovative ECCO2R technique based on ventilation ...
Fan Jui-Lin JL 1University of - - 2013
The present study is the first to examine the effect of high altitude acclimatisation and re-exposure on the responses of cerebral blood flow and ventilation to CO2. We also compared the steady-state estimates of these parameters during acclimatisation with the modified rebreathing method. We assessed changes in steady state responses ...
Desebbe Olivier O Department of Anesthesiology and Intensive Care; Laboratory EA4169, Louis Pradel Hospital, Claude Bernard Lyon 1 University, Lyon, France. Electronic address: - - 2013
To test whether the variations of tissue hemoglobin concentration (∆THb) measured by the FORE-SIGHT(TM) cerebral oximeter can accurately detect changes in arterial hemoglobin concentration (∆AHb) before, during, and after cardiopulmonary bypass. A prospective clinical study. Cardiac surgery operating room. Thirty patients scheduled for cardiac surgery. Tissue hemoglobin concentration (THb) was ...
Lindholm L - - 2013
Gas microembolisation is an identified risk in cardiac surgery. Flooding the wound with carbon dioxide is a method proposed to reduce this problem. The high solubility of carbon dioxide is beneficial, but may also cause problems. The gas solubility diminishes at warming and endogenous bubbles are formed when cold blood ...
Chowdhury Md Albarune - - 2013
Aeration is an important factor influencing CO2, CH4, N2O and NH3 emissions from the composting process. Both CH4 and N2O are potent greenhouse gases (GHG) of high importance. Here, we examined the effects of high and low aeration rates together with addition of barley straw with and without bio-char on ...
Bussy Cyrill - - 2013
Carbon nanotubes may enter into the bloodstream and interact with blood components indirectly via translocation following unintended exposure or directly after an intended administration for biomedical purposes. Once introduced into systemic circulation, nanotubes will encounter various proteins, biomolecules or cells which have specific roles in the homeostasis of the circulatory ...
Soleimanpour Hassan H Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz, - - 2013
Metabolic acidosis confirmed by arterial blood gas (ABG) analysis is one of the diagnostic criteria for diabetic ketoacidosis (DKA). Given the direct relationship between end-tidal carbon dioxide (ETCO2), arterial carbon dioxide (PaCO2), and metabolic acidosis, measuring ETCO2 may serve as a surrogate for ABG in the assessment of possible DKA. ...
Tarafder Abhijit - - 2013
This work demonstrates the possible advantages and the challenges of accurate on-line measurements of the CO2 mass flow rate during supercritical fluid chromatography (SFC) operations. Only the mass flow rate is constant along the column in SFC. The volume flow rate is not. The critical importance of accurate measurements of ...
Beekley Matthew D - - 2013
Abstract The purpose of this study was to examine the effect of changes in capillary blood pH on the resting soleus Hoffmann (H) reflex in the intact human. H-max size, H wave at 20% of M-max, M-max, and H-reflex latency were recorded in 10 subjects (apparently healthy, ages 19 - ...
Ringer S K - - 2013
The aim of the present study was to investigate changes in blood glucose concentration ([Glu]B), acid-base status and electrolyte concentrations during constant rate infusions (CRI) of two alpha2-adrenergic agonists in seven horses treated in a blinded, randomised, crossover design with xylazine or romifidine. An intravenous (IV) bolus of xylazine (1mg/kg) ...
Fierstra Jorn - - 2013
Cerebrovascular reactivity is the change in cerebral blood flow in response to a vasodilatory or vasoconstrictive stimulus. Measuring variations of cerebrovascular reactivity between different regions of the brain has the potential to not only advance understanding of how the cerebral vasculature controls the distribution of blood flow but also to ...
Bulucu Fatih - - 2013
Abstract Blood gas analyses are needed to reveal any kind of acid-base imbalance in some patients. Traditionally, arterial punctures are performed to obtain the blood samples for blood gas analyses. Arterial puncture is not a completely safe procedure. It may cause serious problems including arterial thrombosis, arteriovenous fistula, pseudoaneurysms and ...
Bailey Damian M - - 2013
Age-related impairments in cerebral blood flow and cerebrovascular reactivity to carbon dioxide (CVRCO2) are established risk factors for stroke that respond favorably to aerobic training. The present study examined to what extent cerebral hemodynamics are improved when training is sustained throughout the adult lifespan. Eighty-one healthy males were prospectively assigned ...
Hare Hannah V - - 2013
Measurement of cerebrovascular reactivity (CVR) can give valuable information about existing pathology and the risk of adverse events, such as stroke. A common method of obtaining regional CVR values is by measuring the blood flow response to carbon dioxide (CO2)-enriched air using arterial spin labeling (ASL) or blood oxygen level-dependent ...
Jeon Young-Chul - - 2013
By SF6 gas incorporation for relatively short time during the initial deposition stage, carbon coils could be formed on nickel catalyst layer-deposited silicon oxide substrate using C2H2 and H2 as source gases under thermal chemical vapor deposition system. The characteristics (formation density and morphology) of as-grown carbon coils were investigated ...
Kimmel J D - - 2013
Extracorporeal CO2 removal from circulating blood is a promising therapeutic modality for the treatment of acute respiratory failure. The enzyme carbonic anhydrase accelerates CO2 removal within gas exchange devices by locally catalyzing HCO3 (-) into gaseous CO2 within the blood. In this work, we covalently immobilized carbonic anhydrase on the ...
Kirmizis Dimitrios - - 2013
We studied the diagnostic accuracy of blood gas determination as a novel method for the estimation of arteriovenous fistula (AVF) recirculation (RC). In 25 patients on chronic haemodialysis, with failure of a previously well functioning native AVF (mean two-needle urea-based RC: 41±10%), arterial line (AL) as well as a peripheral ...
Liu Jia - - 2013
In this work, we proposed a novel method to investigate the underlying rapid pressure-to-flow dynamics induced by changes of arterial CO2. Autoregulation was modeled as a multivariate system. The instantaneous effect of CO2 to cerebral blood flow velocity (CBFV) was removed adaptively by the recursive least square (RLS) method from ...
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